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RSRGWSGRWPASDEEAINRILDAADDIVAEHGAAMRLTDVARALGVTRQTVYRYFPGPEAIVVACAMRAA DGFIDQLAAHVRGLTDPVAAMVESVSYSVERLAGDHQFENLLTSRRRGNVTTSLTSETAMTFARSILQRF DIDWKQHGFDETALDELAELSLRTMHSLLVDPGEPPRDGVALRRFVARWLGPAILYPRLARAVDVISPRR *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0372 | - | - | 100% (211) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5152 | - | 2e-49 | 47.69% (195) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3496 | - | 2e-44 | 45.92% (196) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3277c | - | 7e-07 | 27.12% (118) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0364 | - | 8e-86 | 73.08% (208) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 1e-08 | 24.59% (183) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02457 | - | 1e-05 | 23.20% (181) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4765 | - | 3e-44 | 44.62% (195) | putative regulatory protein TetR |
| M. marinum M | MMAR_0226 | - | 1e-40 | 43.37% (196) | hypothetical protein MMAR_0226 |
| M. avium 104 | MAV_2960 | - | 7e-75 | 61.35% (207) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5854 | - | 3e-53 | 50.77% (195) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1262 | - | 3e-53 | 50.77% (195) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4888 | - | 2e-31 | 40.24% (169) | hypothetical protein MUL_4888 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0372|M.vanbaalenii_PYR-1 ---------MRSRGWSGRWPASDEEAINRILDAADDIVAEHG-AAMRLTD
Mflv_0364|M.gilvum_PYR-GCK ---------MRSRGWSGQWPASDEEAITRILDAADELVAADA-SVLRIAD
MAV_2960|M.avium_104 ---------MRSHGWAGNTPASDAEAIERILDAADRIIAERG-SALRIAD
MSMEG_5854|M.smegmatis_MC2_155 ---------MRTHGWSGSAPATDEEAIARILAAAGKAIDERG-ADFSIAD
TH_1262|M.thermoresistible__bu ---------MRTHGWGGSAPASDEEAIARILEAAKRTIEERG-AEFSIAD
MMAR_0226|M.marinum_M --------MARRRGWNGAPPASDEEASRRIVDTAVRLIAETG-SDVSLAQ
MUL_4888|M.ulcerans_Agy99 --------MVSRPKRRGVSRIG------RGVRRHRRGIAETG-SDVSLAQ
MAB_4765|M.abscessus_ATCC_1997 --------MARRRGWDGQPPSSDEEAAERIVAAAVKLIGETG-SAVSLAD
Rv1255c|M.tuberculosis_H37Rv ---------MAGTDWLS--ARRTELAADRILDAAERLFTQRDPASIGMNE
Mb3277c|M.bovis_AF2122/97 --MSTPSATVAPVKRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSD
MLBr_02457|M.leprae_Br4923 MAEHIPAVAVKTDGRKRRWHQHKVERRNELVDGTIDAIRRQG-RFLSMDE
: . . : :
Mvan_0372|M.vanbaalenii_PYR-1 VARALGVTRQTVYRYFPGPEAIVVACAMRAADG-FIDQLAAHVRG-LTDP
Mflv_0364|M.gilvum_PYR-GCK VARALGVTRQTVYRYFPHPEAIRLACAMRAADG-FFDRLAKQVGG-MTDP
MAV_2960|M.avium_104 VARALGVTRQTVYRYFPGTQALLVASAMRSADG-FLDRMAAHLDG-VTDP
MSMEG_5854|M.smegmatis_MC2_155 VARTLGVTRQTVYRYFPSTDALLVAAAVHAASG-FLDRLAAHLSG-ITDP
TH_1262|M.thermoresistible__bu VARAVGVTRQTVYRYFPSTDALLVAAAMHAAGD-FLDRLAVHLQG-ITDP
MMAR_0226|M.marinum_M VAASLGVIRQTVYRYYPTADALMRAAAIASVDG-FLDRLTEAVRG-MRDP
MUL_4888|M.ulcerans_Agy99 VAASLGVIRQTVYRYYPTADALMRAAAIASVDG-FLDRLTEAVRG-MRDP
MAB_4765|M.abscessus_ATCC_1997 VAAELGVIRQTVYRYFPTADALMHAASLASVDG-FLDRLTHVVRG-ITDP
Rv1255c|M.tuberculosis_H37Rv IAKAAGCSRATLYRYFDSREALRTAYVHRETRR-LGREIMVKIAD-VVEP
Mb3277c|M.bovis_AF2122/97 VARAAGISRQTIYNEFGSRQGLAQGYALRLADR-LVDNVHASLDANVGNF
MLBr_02457|M.leprae_Br4923 IAGKIGVSKTVLYRYFIDKNDLTTAVMMRFAQTTLIPNMAAALST-NLDG
:* * : .:*. : : : . . : .: : :
Mvan_0372|M.vanbaalenii_PYR-1 VAAMVESVSYSVERLAGDHQFENLLTSRRRGNV-TTSLTSETAMTFARSI
Mflv_0364|M.gilvum_PYR-GCK VAVMVECVASAVERLAGDPQFEALVTARRHGAR-AVSLTSDTALTFARTI
MAV_2960|M.avium_104 VVAITEGMAFAVEELASDHQVEFVLNQRHRGGQ-KVSIISDTALAFGRSM
MSMEG_5854|M.smegmatis_MC2_155 VEAVTEAIATALEWVPQDKHLGLLISPGRADAH-TESVTSDVAVDFARAM
TH_1262|M.thermoresistible__bu VEAVAEAIATTLEWLPEDTHIGLLVAPGRPTAH-TESVTSDVAIDFANRM
MMAR_0226|M.marinum_M AEAMAEAVMFTLRDVVRTPHLGILIAQPYAHTH-PENLTSEEAQVFGVRM
MUL_4888|M.ulcerans_Agy99 AEAMAEAVMFTLRDVVRTPHLGILIAQPYAHTH-PENLTSEEAQVFGVRM
MAB_4765|M.abscessus_ATCC_1997 AEALTEGVLYTLEEVTRTPHLGIMMSEPYAHSH-TSDMTSDEAQAFGLRM
Rv1255c|M.tuberculosis_H37Rv AERLLVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSEVIAALAAAF
Mb3277c|M.bovis_AF2122/97 YEAFLQGFRSFFAESAADPLVISLLTGVAKPDL-LQLITTDSAPIITRAS
MLBr_02457|M.leprae_Br4923 FDLTREIIRVYVKTVAAEPEPYQFVMANSSASKSKVIADSERIIARMLAV
. . . ::
Mvan_0372|M.vanbaalenii_PYR-1 LQRFDIDWKQHGF-DETALDELAELSLRTMHSLLVDPGE-PPRDGVALRR
Mflv_0364|M.gilvum_PYR-GCK LHRFDIDWEQHGF-DTAGLDRLAELSIRTVHSILVDPGD-PAREGAELRR
MAV_2960|M.avium_104 LHRYDIDWESYGF-DEAGLEELNEFSLRVLHSFLTDPGR-PPRTGADLRR
MSMEG_5854|M.smegmatis_MC2_155 LRKFDVDWAGLGF-GDDDLDELAEHLLRIIQSFIIDPGR-PPRTGATLRS
TH_1262|M.thermoresistible__bu LRRFDVDWAAVGY-SDADLDELAEHLLRVIQSFVIDPGR-PPRDGQSLRA
MMAR_0226|M.marinum_M LERFDVDWAEYGFADESARHDLVEFLLRVLLSFFVAPNV-PSRSDDELKS
MUL_4888|M.ulcerans_Agy99 LERFDVDWAEYGFADESARHDLVEFLLRVLLSFFVAPNV-PSRSDDELKS
MAB_4765|M.abscessus_ATCC_1997 LDRFDVDWVQYGY-DDAAKRELVEFALRIMLSFFVSPNE-ATRSRDELRG
Rv1255c|M.tuberculosis_H37Rv LN-------SLGPDDPTTVERRARWVVRMLTSLLMFPGRDEADERAMIAE
Mb3277c|M.bovis_AF2122/97 ARLAPAFTDTWVATTDNDANVLSRAIVRLCLSYVSMPPEADHDVAADLAR
MLBr_02457|M.leprae_Br4923 MIRRRMQEAGMDAGGVEPWAYLIVGGVQLATHSWMSDPRMSADELIDYLT
::
Mvan_0372|M.vanbaalenii_PYR-1 FVAR-------WLGPAILYPRLARAVDVIS--------PRR-----
Mflv_0364|M.gilvum_PYR-GCK FVAG-------WLGPAILYPRLARAVDAITAPGVSPASPMRY----
MAV_2960|M.avium_104 YLTR-------WIGPAIAYPQLLRAMDALGAAEPQQRPRRRASKAS
MSMEG_5854|M.smegmatis_MC2_155 YLRR-------WVGAAVKPAQASVQSPRV-----------------
TH_1262|M.thermoresistible__bu YLRR-------WVGAAVTGAR-------------------------
MMAR_0226|M.marinum_M FIKR-------WVGGAILAQKR------------------------
MUL_4888|M.ulcerans_Agy99 FIRR-------WVGGAIVAQKR------------------------
MAB_4765|M.abscessus_ATCC_1997 FLKR-------WLGGAVLAQGR------------------------
Rv1255c|M.tuberculosis_H37Rv FVVP-------IVTPASAAARKAGHPGPE-----------------
Mb3277c|M.bovis_AF2122/97 LITP-------FAERHGVINVP------------------------
MLBr_02457|M.leprae_Br4923 MLSWNALCGIVEVGGSLEKFRKQPHPSPIIPPRGP-----------
: