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MARRRGWDGQPPSSDEEAAERIVAAAVKLIGETGSAVSLADVAAELGVIRQTVYRYFPTADALMHAASLA SVDGFLDRLTHVVRGITDPAEALTEGVLYTLEEVTRTPHLGIMMSEPYAHSHTSDMTSDEAQAFGLRMLD RFDVDWVQYGYDDAAKRELVEFALRIMLSFFVSPNEATRSRDELRGFLKRWLGGAVLAQGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4765 | - | - | 100% (201) | putative regulatory protein TetR |
| M. abscessus ATCC 19977 | MAB_2043 | - | 9e-13 | 32.93% (167) | putative transcriptional regulator, TetR |
| M. abscessus ATCC 19977 | MAB_2606c | - | 1e-06 | 32.00% (125) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3011 | - | 1e-71 | 65.48% (197) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1255c | - | 4e-05 | 29.25% (106) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0226 | - | 5e-80 | 67.82% (202) | hypothetical protein MMAR_0226 |
| M. avium 104 | MAV_2960 | - | 6e-47 | 45.36% (194) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2106 | - | 1e-88 | 77.61% (201) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_1262 | - | 2e-47 | 47.94% (194) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4888 | - | 6e-67 | 66.47% (173) | hypothetical protein MUL_4888 |
| M. vanbaalenii PYR-1 | Mvan_3496 | - | 1e-67 | 63.45% (197) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3011|M.gilvum_PYR-GCK ------------------MARKRRGWGGNPPETDEEATRRIVAAAVDLIA
Mvan_3496|M.vanbaalenii_PYR-1 MVTASPVRRQRLCYRRATMARKRRGWGGDPPATDSEAAQRIVVAAVDLIA
MAB_4765|M.abscessus_ATCC_1997 ------------------MAR-RRGWDGQPPSSDEEAAERIVAAAVKLIG
MSMEG_2106|M.smegmatis_MC2_155 ------------------MAR-RRGWDGRPPANDEEASARIVEAAVALIS
MMAR_0226|M.marinum_M ------------------MAR-RRGWNGAPPASDEEASRRIVDTAVRLIA
MUL_4888|M.ulcerans_Agy99 ------------------MVS-RPKRRGVSRIG------RGVRRHRRGIA
MAV_2960|M.avium_104 ------------------MRS--HGWAGNTPASDAEAIERILDAADRIIA
TH_1262|M.thermoresistible__bu ------------------MRT--HGWGGSAPASDEEAIARILEAAKRTIE
Rv1255c|M.tuberculosis_H37Rv ------------------MAG--TDWLS--ARRTELAADRILDAAERLFT
* . * : :
Mflv_3011|M.gilvum_PYR-GCK ETG-SAITIADVAESLGVIRQTVYRYFPTAQDLMREAAIASVDGFLDQLE
Mvan_3496|M.vanbaalenii_PYR-1 RTG-AAITIADVAESLEVTRQTVYRYFSTADELMRAAAIASVDGFLDQLA
MAB_4765|M.abscessus_ATCC_1997 ETG-SAVSLADVAAELGVIRQTVYRYFPTADALMHAASLASVDGFLDRLT
MSMEG_2106|M.smegmatis_MC2_155 ETG-SDVSIADVAASLGVIRQTVYRYFPTADALMRAAAIASVDGFLDRLT
MMAR_0226|M.marinum_M ETG-SDVSLAQVAASLGVIRQTVYRYYPTADALMRAAAIASVDGFLDRLT
MUL_4888|M.ulcerans_Agy99 ETG-SDVSLAQVAASLGVIRQTVYRYYPTADALMRAAAIASVDGFLDRLT
MAV_2960|M.avium_104 ERG-SALRIADVARALGVTRQTVYRYFPGTQALLVASAMRSADGFLDRMA
TH_1262|M.thermoresistible__bu ERG-AEFSIADVARAVGVTRQTVYRYFPSTDALLVAAAMHAAGDFLDRLA
Rv1255c|M.tuberculosis_H37Rv QRDPASIGMNEIAKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIM
. . : . : ::* * *:***: : * . : .:
Mflv_3011|M.gilvum_PYR-GCK ARVRGITDPADAMTEGFLFTLDAVVAIPHLGILLSSPSS-AATPGEVASA
Mvan_3496|M.vanbaalenii_PYR-1 AHVRGIHDPADAMTEGVMFTLDAVAAIPHLAILLSAPSE-AARPSEVTSD
MAB_4765|M.abscessus_ATCC_1997 HVVRGITDPAEALTEGVLYTLEEVTRTPHLGIMMSEPYA-HSHTSDMTSD
MSMEG_2106|M.smegmatis_MC2_155 AHVRGITDPAEAMTDGVLYTLEEVSRTPHLGIVLSEPYL-HANSGSLASD
MMAR_0226|M.marinum_M EAVRGMRDPAEAMAEAVMFTLRDVVRTPHLGILIAQPYA-HTHPENLTSE
MUL_4888|M.ulcerans_Agy99 EAVRGMRDPAEAMAEAVMFTLRDVVRTPHLGILIAQPYA-HTHPENLTSE
MAV_2960|M.avium_104 AHLDGVTDPVVAITEGMAFAVEELASDHQVEFVLNQRHR-GGQKVSIISD
TH_1262|M.thermoresistible__bu VHLQGITDPVEAVAEAIATTLEWLPEDTHIGLLVAPGRP-TAHTESVTSD
Rv1255c|M.tuberculosis_H37Rv VKIADVVEPAERLLVSITTTLRMVRDNPALAAWFTTTRPPIGGEMAGRSE
: .: :*. : .. :: : : . *
Mflv_3011|M.gilvum_PYR-GCK LAQDVGMRMITRFDVDWQRYGY-DDAALRDLVEFTLRTMLSFFVAPNDPS
Mvan_3496|M.vanbaalenii_PYR-1 LAQDFGMRMITRFDVDWQRYGY-DDAALRDLVEFTLRTMLSFFVAPN--V
MAB_4765|M.abscessus_ATCC_1997 EAQAFGLRMLDRFDVDWVQYGY-DDAAKRELVEFALRIMLSFFVSPNEAT
MSMEG_2106|M.smegmatis_MC2_155 EAQDFGMRMLKRFDVDWAAYGY-DEAAQRELVEFTLRIMLSFFVAPNEAT
MMAR_0226|M.marinum_M EAQVFGVRMLERFDVDWAEYGFADESARHDLVEFLLRVLLSFFVAPNVPS
MUL_4888|M.ulcerans_Agy99 EAQVFGVRMLERFDVDWAEYGFADESARHDLVEFLLRVLLSFFVAPNVPS
MAV_2960|M.avium_104 TALAFGRSMLHRYDIDWESYGF-DEAGLEELNEFSLRVLHSFLTDPGRPP
TH_1262|M.thermoresistible__bu VAIDFANRMLRRFDVDWAAVGY-SDADLDELAEHLLRVIQSFVIDPGRPP
Rv1255c|M.tuberculosis_H37Rv VIAALAAAFLN-------SLGPDDPTTVERRARWVVRMLTSLLMFPG---
.. :: * . : . :* : *:. *.
Mflv_3011|M.gilvum_PYR-GCK RSREELRRFLRRWLGSAILAQASPSRISPSISSTG------------
Mvan_3496|M.vanbaalenii_PYR-1 RPPEELRRFLTRWLGSAILAQSVKA----------------------
MAB_4765|M.abscessus_ATCC_1997 RSRDELRGFLKRWLGGAVLAQGR------------------------
MSMEG_2106|M.smegmatis_MC2_155 RSREELRRFIRRWLGGALLAQPRATAAPSSST---------------
MMAR_0226|M.marinum_M RSDDELKSFIKRWVGGAILAQKR------------------------
MUL_4888|M.ulcerans_Agy99 RSDDELKSFIRRWVGGAIVAQKR------------------------
MAV_2960|M.avium_104 RTGADLRRYLTRWIGPAIAYPQLLRAMDALGAAEPQQRPRRRASKAS
TH_1262|M.thermoresistible__bu RDGQSLRAYLRRWVGAAVTGAR-------------------------
Rv1255c|M.tuberculosis_H37Rv RDEADERAMIAEFVVPIVTPASAAARKAGHPGPE-------------
* . : : .:: :