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MTGPGRGRPRDAAADRAILHAALDLFIERGVEGTSIEQIARRAGVGKPTIYRRWSTKEDLIAAAMETLVA EEVVWASPEEIESRSPHVLVEAAIESAAATTASPSYRALVARVYGSAVSHPGLMAVYWDRYILPRRAQAR RLLERARELGTVSEDTDLDVAIDMMVGAITYRVLQPDPPDVDGMRRYLRAVYRQIGLLS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1500 | - | - | 100% (199) | TetR family protein transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_5301 | - | 3e-18 | 33.33% (180) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3834 | - | 4e-17 | 32.14% (168) | putative TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 2e-14 | 31.07% (177) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_5008 | - | 5e-92 | 84.85% (198) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 2e-14 | 31.07% (177) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 1e-07 | 46.97% (66) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4749c | - | 2e-16 | 31.25% (176) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2979 | - | 6e-14 | 29.34% (167) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4057 | - | 8e-15 | 30.39% (181) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4110 | - | 3e-64 | 58.55% (193) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_2482 | - | 4e-13 | 28.07% (171) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0778 | - | 2e-81 | 77.72% (193) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1500|M.smegmatis_MC2_155 -----------MTGPG---RGRPRDAAADRAILHAALDLFIERGVEGTSI
Mflv_5008|M.gilvum_PYR-GCK -----------MTAPV---RGRPRDPDADRAILQAALDLFIERGVEGSSI
Mvan_0778|M.vanbaalenii_PYR-1 -----------MTAS----RGRPRDAGADVAILRAGLELFIERGVEGTSM
TH_4110|M.thermoresistible__bu --VTATDAAATGRAAA---RGRPRDPALDSAILDAALEIFVEQGISALSI
Mb3192c|M.bovis_AF2122/97 ---MKADLPSLDKAP---GAGRPRDPRIDSAILSATAELLVQIGYSNLSL
Rv3167c|M.tuberculosis_H37Rv ---MKADLPSLDKAP---GAGRPRDPRIDSAILSATAELLVQIGYSNLSL
MAV_4057|M.avium_104 ---MKADPSGLDKAP---GAGRPRDPRIDSAILSATAELLVQTGYSNISL
MUL_2482|M.ulcerans_Agy99 ---MKADPSSLDKAP---GAGRPRDPRIDFAILSATMELLVQIGYSNLSL
MMAR_2979|M.marinum_M ---MESTAWTDQPEPRVRSQGRPRDARIDAAVLRATTELLEEIGYARLTI
MAB_4749c|M.abscessus_ATCC_199 ---------MNGTRPRQPRRGRRPTEEVREEVLQAAGELLFTEGMGGFTI
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPAR--PLRADAARNRARILGVAYEAFATEGLS-VPI
. * :* . : : * .:
MSMEG_1500|M.smegmatis_MC2_155 EQIARRAGVGKPTIYRRWSTKEDLIAAAMETLVAEEVVWASPEEIESRSP
Mflv_5008|M.gilvum_PYR-GCK EQIAKRAGVGKPTVYRRWGTKEELIAAAMETLVAEEVGWTSPEAIETRSP
Mvan_0778|M.vanbaalenii_PYR-1 EQIARKAGVGKPTIYRRWATKEELISAAMETLVVAETGWASPEAIATESP
TH_4110|M.thermoresistible__bu EQVARRAGVGKPTIYRRWSDKEQLVADAIEHRVSAELAWPTPAEASVSDP
Mb3192c|M.bovis_AF2122/97 AAVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAGDIAAD---
Rv3167c|M.tuberculosis_H37Rv AAVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAGDIAAD---
MAV_4057|M.avium_104 AAVAERAGTTKSALYRRWSSKAELVHEAAFPTAPTALEAPAGDIAAD---
MUL_2482|M.ulcerans_Agy99 AAVAERAGTTKSALYRRWSSKAELVHEAAFPVTPSALSAPAGDFAGD---
MMAR_2979|M.marinum_M PLVAARAGATPPAVYRRFPTKIELVYEAVFPNPTSTELPLTDGLESG---
MAB_4749c|M.abscessus_ATCC_199 DKVAALSGASKMTIYKWWPSKGALALDGYFRKVEPDLNFPDSGEIER---
MLBr_00316|M.leprae_Br4923 DEIARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLKSAGPG
:* :*. ::*: : * *
MSMEG_1500|M.smegmatis_MC2_155 HVLVEAAIESAAATTASPSYRALVARVYGSAVSHPGLMAVYWDRYILPRR
Mflv_5008|M.gilvum_PYR-GCK HVLVEAAIDSAAAATAAPYYRALVARVYGSAVSHPELMTVYWDRYILPRR
Mvan_0778|M.vanbaalenii_PYR-1 YELVEAAIEGAAVATTTPQYRALVARVFGSAVSHPELMATYWRRYILPRR
TH_4110|M.thermoresistible__bu YELVRRNISAAARTAADPAFRGLIAAIYGSAVTHPALLRTYWEHYILPRR
Mb3192c|M.bovis_AF2122/97 ---IRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARF-ADLF
Rv3167c|M.tuberculosis_H37Rv ---IRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARF-ADLF
MAV_4057|M.avium_104 ---MRMMIEATRDVFTTPVVRAALPGLVADMTADPALNARVMSRF-ADLF
MUL_2482|M.ulcerans_Agy99 ---IRMMVAATRDVFTTPVVRAALPGLVADMTAEADLNARVLSRF-TELF
MMAR_2979|M.marinum_M ---IRALLRAAIDLFSRPAVHSALSGLMAELPSEPGLSARLLSRLQSSSY
MAB_4749c|M.abscessus_ATCC_199 --DLRAQMRAFLGVIRDTAAGAIIGELIGQAQVDPELKAAFLQRYSGPRR
MLBr_00316|M.leprae_Br4923 --EALFTYLRSLVLHWGATDRGLVDALAGAGGID---ILGVAPDAEDAFL
. . : : . .
MSMEG_1500|M.smegmatis_MC2_155 AQARRLLERARELGTVSEDTDLDVAIDMMVGAITYRVLQPDPPDVDGMRR
Mflv_5008|M.gilvum_PYR-GCK VQATRLLERARELGTVAADTDLDVAIDMMVGAITYRVLRPNPPDVDEMRR
Mvan_0778|M.vanbaalenii_PYR-1 RLAAALLERARELGTVAADANPDVAIDMMVGAVTYRVLQPDPPDVDEMRR
TH_4110|M.thermoresistible__bu TAAIALLRRARDLGTVAADADLDVLVDMLAGAVTYRVLQPEPPSARQLRC
Mb3192c|M.bovis_AF2122/97 AAVRMRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLDDAWV
Rv3167c|M.tuberculosis_H37Rv AAVRMRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLDDAWV
MAV_4057|M.avium_104 TAVRVRLGEAVDRGEAHPDVDPDRLIELIGGATMLRMLLRPEEELDDAWV
MUL_2482|M.ulcerans_Agy99 ATVRIRLQEAVDRGEAHPDVDPNRMIELIGGATMLRVLLYPDQMLDEAWV
MMAR_2979|M.marinum_M GQLQRFLDHAAASGQATPDVDARILLDMIGGTVMMALANERD--LDAAWM
MAB_4749c|M.abscessus_ATCC_199 ALAVAAIRRAQERGQLRANVDPEVMVDQLWGACYHRLLVPDQP-LTAGFV
MLBr_00316|M.leprae_Br4923 TILSDLLYAAQYAGTARTDVGVREVKSILVGCQAMEAY-------NSALA
: * * :.. . : *
MSMEG_1500|M.smegmatis_MC2_155 YLRAVYRQIGLLS--------
Mflv_5008|M.gilvum_PYR-GCK YLREVYRQAGLLPPG------
Mvan_0778|M.vanbaalenii_PYR-1 YLREVYRQVGLLPD-------
TH_4110|M.thermoresistible__bu YLEVAYRQVGLLP--------
Mb3192c|M.bovis_AF2122/97 DQTTAIVVRGVHRAAPGGSVV
Rv3167c|M.tuberculosis_H37Rv DQTTAIVVRGVHRAAPGGSVV
MAV_4057|M.avium_104 EQTTAIVVHGVRR--------
MUL_2482|M.ulcerans_Agy99 DQTTAILVHGVTR--------
MMAR_2979|M.marinum_M DHTTTLLLGGLAR--------
MAB_4749c|M.abscessus_ATCC_199 DALLDNLFKGIGA--------
MLBr_00316|M.leprae_Br4923 ERVTDVVVDGLRAAR------
*: