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MESTAWTDQPEPRVRSQGRPRDARIDAAVLRATTELLEEIGYARLTIPLVAARAGATPPAVYRRFPTKIE LVYEAVFPNPTSTELPLTDGLESGIRALLRAAIDLFSRPAVHSALSGLMAELPSEPGLSARLLSRLQSSS YGQLQRFLDHAAASGQATPDVDARILLDMIGGTVMMALANERDLDAAWMDHTTTLLLGGLAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2979 | - | - | 100% (202) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0340 | - | 7e-37 | 44.74% (190) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1394 | - | 2e-35 | 43.09% (188) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3192c | - | 6e-35 | 43.09% (188) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4384 | - | 5e-33 | 41.08% (185) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3167c | - | 6e-35 | 43.09% (188) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0832 | - | 6e-18 | 34.18% (158) | TetR family transcriptional regulator |
| M. avium 104 | MAV_5165 | - | 3e-39 | 45.95% (185) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2043 | - | 1e-32 | 41.94% (186) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0688 | - | 9e-31 | 39.57% (187) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_4780 | - | 2e-36 | 44.21% (190) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1870 | - | 5e-35 | 42.27% (194) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3192c|M.bovis_AF2122/97 --------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNL
Rv3167c|M.tuberculosis_H37Rv --------MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNL
MSMEG_2043|M.smegmatis_MC2_155 --------MKAEASPLGKGVGAGRPRDPRIDAAILRATAELLVEIGYANL
Mvan_1870|M.vanbaalenii_PYR-1 --------MNTDPSPGDKTPGAGRPRDPRIDAAILRATADLLVEIGYSNV
TH_0688|M.thermoresistible__bu --------MTTNSTSVDKAAGAGRPRDPRIDGAILRATADLLVEIGYSNL
MAV_5165|M.avium_104 -------------------MDFGRPRDPRIDAAVLRATVELLAETGYPGL
MUL_4780|M.ulcerans_Agy99 -----------------MVADFGRPRDPRIDGAVLRATVELLAETGYAGL
Mflv_4384|M.gilvum_PYR-GCK MPSVVSVTESYVTLSIVMTTDIGRPRNRAIADAVLRATVELLAESSYAEL
MMAR_2979|M.marinum_M -----MESTAWTDQPEPRVRSQGRPRDARIDAAVLRATTELLEEIGYARL
MAB_0832|M.abscessus_ATCC_1997 ----------------MDKRQGGRPRDPDKDDAVRETVRRMLAADGYQRT
****: *: :. :* .*
Mb3192c|M.bovis_AF2122/97 SLAAVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAGDIAADI
Rv3167c|M.tuberculosis_H37Rv SLAAVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAGDIAADI
MSMEG_2043|M.smegmatis_MC2_155 TMAAVAERAQTTKTALYRRWSSKAELVHEAVFPAVPTGLVAPAGDIAADV
Mvan_1870|M.vanbaalenii_PYR-1 TMAAVAERAGTTKTALYRRWSSKAELVHEAAFPVTPTAIQTPPGDIAADL
TH_0688|M.thermoresistible__bu TMSAVAERAGTTKTALYRRWSSKPELVYAATAPTDPVDTVESSDDVAGIV
MAV_5165|M.avium_104 LVSAIAQRAGTSKPAIYRRWPSKAHLVHEAVFPVGADTAIPDTGSTADDL
MUL_4780|M.ulcerans_Agy99 LVSAIAKRAGTSKPAIYRRWPSKAHLVHEAVFPIDAATAVPDTGSPVDDL
Mflv_4384|M.gilvum_PYR-GCK SLDAVAARAGTSKPAIYRRWRGKAHLVHEAVFPLGADTAIPGSGSLEADV
MMAR_2979|M.marinum_M TIPLVAARAGATPPAVYRRFPTKIELVYEAVFPNPTSTELPLTDGLESGI
MAB_0832|M.abscessus_ATCC_1997 TIPAVARAAGIGAPTIYRRWPTQAAMVESAIADRPWPEELAAPSEFRYYL
: :* * .::***: : :* * .. :
Mb3192c|M.bovis_AF2122/97 RMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADLFA-AVR
Rv3167c|M.tuberculosis_H37Rv RMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADLFA-AVR
MSMEG_2043|M.smegmatis_MC2_155 HAMIAAARDVFTSPVVRAALPGLIADVSADANLNARVMERFTGVFA-AVR
Mvan_1870|M.vanbaalenii_PYR-1 RAMIEAARDVFTSPVVRSALPGLIADLSADADLAGRVGARFTDLFA-AVR
TH_0688|M.thermoresistible__bu RALIERNRQITATPAARAAMPGLLVDMAADPRLHRGLLGRVGSLVE-ALR
MAV_5165|M.avium_104 REMVRRTMVFLTTPAAKAALPGLIGEMAADPSLHSALLERFAGAIGGGLA
MUL_4780|M.ulcerans_Agy99 REMVRRTTAVLSTPAAKAAQPGLIGEMAADPTLHSALLVRFGEIFGHGLT
Mflv_4384|M.gilvum_PYR-GCK REMTRRTLAVLSTPAALAALPGLVGEMASDPTLHTALLERFGDILVRGLT
MMAR_2979|M.marinum_M RALLRAAIDLFSRPAVHSALSGLMAELPSEPGLSARLLSRLQSSSYGQLQ
MAB_0832|M.abscessus_ATCC_1997 PVLVRAVVGYFADPATRAAMPGLLVEYYREPSQYVVLAERTEMPLREAFR
: : *.. :* .**: : :. : * .
Mb3192c|M.bovis_AF2122/97 MRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD----DAWV
Rv3167c|M.tuberculosis_H37Rv MRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLD----DAWV
MSMEG_2043|M.smegmatis_MC2_155 ERIVDGIARGEVHAAVSPDRLVEIIGGATMLRLLLVSDENLD----DEWV
Mvan_1870|M.vanbaalenii_PYR-1 NRLHDAVERGEVRAGVDPDQLVNLIGGATLLALLQAPDDLTA----PAWV
TH_0688|M.thermoresistible__bu RRLAEAAGRGEVQSGVDADRLTELIGGSVMFRMVLHPDEPIT----ERWA
MAV_5165|M.avium_104 DWLAAAAARGEARPDVTAAELAETIAGVTLVALLTRPTELD-----DAWV
MUL_4780|M.ulcerans_Agy99 TWLDNAAARGQVRADVTAPELAEAIAGIVLIGLLTRPGELEPGVG-DAWI
Mflv_4384|M.gilvum_PYR-GCK EFLESAVRRGDVRPDVTASDLAEAVAGMTLLALLTRGTAVD-----EVWL
MMAR_2979|M.marinum_M RFLDHAAASGQATPDVDARILLDMIGGTVMMALANE-RDLDA-----AWM
MAB_0832|M.abscessus_ATCC_1997 RAHAGAVGSGERADQPGADALFDTIVGMAVYHGVLRGTADDALVEQILDV
. *: . * : : * .:
Mb3192c|M.bovis_AF2122/97 DQTTAIVVRGVHRAAPGGSVV---
Rv3167c|M.tuberculosis_H37Rv DQTTAIVVRGVHRAAPGGSVV---
MSMEG_2043|M.smegmatis_MC2_155 HQTAAIVIHGVTVGR---------
Mvan_1870|M.vanbaalenii_PYR-1 DRTTDILLHGVMA-----------
TH_0688|M.thermoresistible__bu DEVAAILIRGVTKEG---------
MAV_5165|M.avium_104 DRTTRLLLKGISA-----------
MUL_4780|M.ulcerans_Agy99 DRTTTLLLKGIRKGTPQ-------
Mflv_4384|M.gilvum_PYR-GCK DRTARLITKGISA-----------
MMAR_2979|M.marinum_M DHTTTLLLGGLAR-----------
MAB_0832|M.abscessus_ATCC_1997 VDAASSVGRGLHLDETNSDKERKR
.: : *: