For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SSTPSADEGSPSNLMLRGRLIDALRSDVIRGRYPPGYRLVERDVADAYGVSRLPAREALQALKTEGFLEV RKTRGLVVRGWTERDVTELFDIRQALEAMACREAAENRTDEDIAALRGAAESADRAAERNDVTAAHDANA LFHQLLVTASHNRTLGEIMAPILYRVQWLVRQIPDPHAVSDDHHRLVDAIADRDARAAEKLAKDHADRNR TTTLQTLFGAGTRRSQLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1317 | - | - | 100% (229) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_0166 | - | 8e-25 | 31.51% (219) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4042 | - | 1e-20 | 33.64% (220) | transcriptional regulator, GntR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0505 | - | 3e-13 | 32.67% (202) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0016 | - | 4e-17 | 32.34% (201) | GntR domain-containing protein |
| M. tuberculosis H37Rv | Rv0494 | - | 3e-13 | 32.67% (202) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4411c | - | 2e-18 | 32.63% (190) | GntR family transcriptional regulator |
| M. marinum M | MMAR_2244 | - | 4e-11 | 24.07% (216) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0339 | - | 2e-16 | 29.00% (200) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3342 | - | 5e-17 | 30.98% (184) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_4564 | - | 4e-11 | 27.23% (213) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3051 | - | 3e-19 | 29.15% (223) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0505|M.bovis_AF2122/97 ---------MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGST
Rv0494|M.tuberculosis_H37Rv ---------MVEPMNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGST
MUL_4564|M.ulcerans_Agy99 -------------MNQSSILQPPDRQRVDEQIATSIADAILDGVFPPGSA
Mflv_0016|M.gilvum_PYR-GCK ---------MIGRKDIRVPLSTARRSGLVEQVIDQLRHAVAGQEWRIGDR
MSMEG_1317|M.smegmatis_MC2_155 -----------MSSTPSADEGSPSNLMLRGRLIDALRSDVIRGRYPPGYR
MAB_4411c|M.abscessus_ATCC_199 -----------MTTLVPEEFAPLERQSTAELIAERLRIAIMRGVLAPGAQ
Mvan_3051|M.vanbaalenii_PYR-1 -----------MAAPTEEPSRLALPATLVEVAGNRLRDAILSGELAPGEK
MMAR_2244|M.marinum_M MLEEEAVVIPRADSPDQTCGRLPARGTIGEQVADLIQESILSGEAKRGAP
MAV_0339|M.avium_104 ------------------MAAIDISGTVRERAARELRDRILTGALPAGSR
TH_3342|M.thermoresistible__bu ----------------VAVPEFAARPQLAEDVARYVRRRIFDGTYAAGEY
: : *
Mb0505|M.bovis_AF2122/97 LPPERDLAERLGVNRTSLRQGLARLQQMGLIEVRHGSGSVVRDPEGLTHP
Rv0494|M.tuberculosis_H37Rv LPPERDLAERLGVNRTSLRQGLARLQQMGLIEVRHGSGSVVRDPEGLTHP
MUL_4564|M.ulcerans_Agy99 LPPERELAEQLGVNRTSLRQGLARLQQMGLIETRQGSGNVVRDPQSLTHP
Mflv_0016|M.gilvum_PYR-GCK IPNETVLVEKFGVGRNTVREAVRALAHAGILEVRQGDGTYVR------AT
MSMEG_1317|M.smegmatis_MC2_155 L-VERDVADAYGVSRLPAREALQALKTEGFLEVRKTRG------------
MAB_4411c|M.abscessus_ATCC_199 L-GEASLAAQFAVSRGPLREAMQRLVSEGLLRSERNRG------------
Mvan_3051|M.vanbaalenii_PYR-1 I-IEEQLCADFGISRAPLREALRRLAQQGLVEHLPRRG------------
MMAR_2244|M.marinum_M L-REELIADRYQVSRRTVRDALRVLESNGLVRHQRHKG------------
MAV_0339|M.avium_104 I-DLDAITAEFATSRTPVREALLELSFEGLVQVAPRSG------------
TH_3342|M.thermoresistible__bu V-RLDQLAVELGVSVTPVREALFQLRAEGLLVQQPRRG------------
: : . . *:.: * *:: *
Mb0505|M.bovis_AF2122/97 AVVEALVRKLGPDFLVELLEIRAALGPLIGR---LAAARSTPEDAEALCA
Rv0494|M.tuberculosis_H37Rv AVVEALVRKLGPDFLVELLEIRAALGPLIGR---LAAARSTPEDAEALCA
MUL_4564|M.ulcerans_Agy99 AVVEALVRKLGPDFLVEVLEIRAALGPLIGR---LAAERNSSEDAEALRA
Mflv_0016|M.gilvum_PYR-GCK SEVSGALRRLCGEELREVLEVRRALEVEAAR---LAASRRTPADVAEMRG
MSMEG_1317|M.smegmatis_MC2_155 ----LVVRGWTERDVTELFDIRQALEAMACR---EAAENRTDEDIAALRG
MAB_4411c|M.abscessus_ATCC_199 ----IFVIELTDDDVLDVYRSRSAIERAALE---CIMTGDTVTAYRRLLV
Mvan_3051|M.vanbaalenii_PYR-1 ----SRVTEWSPTDILQLFELRNVLERHAIE---SALP--LADLDRDLEP
MMAR_2244|M.marinum_M ----STVVDFSAEDITDMYRSREVLELDAAKRWCRAGEVDSGYRFHRLTE
MAV_0339|M.avium_104 ----VTVIGISPEDVLDSFTILGVLTGQAAA---WAAERIGPEELATLRE
TH_3342|M.thermoresistible__bu ----FMVLPVTERDLTDIANVQAHVGGELAA---RAAQNITDEQLRVLTA
: : : : :
Mb0505|M.bovis_AF2122/97 ALEVVQQADTA---AARQAADLAYFRVLIHSTRNRALGLLYRWVEHAFGG
Rv0494|M.tuberculosis_H37Rv ALEVVQQADTA---AARQAADLAYFRVLIHSTRNRALGLLYRWVEHAFGG
MUL_4564|M.ulcerans_Agy99 ALAEVADADTA---PARQAADLAYFRVLIHGTRNRALGLLYRWVEQAFGG
Mflv_0016|M.gilvum_PYR-GCK LLARRDERDSAGDVEAFARIDTEFHLAVVRCARNNTLIELYRGLLEAVTA
MSMEG_1317|M.smegmatis_MC2_155 AAESADRAAERNDVTAAHDANALFHQLLVTASHNRTLGEIMAPILYRVQW
MAB_4411c|M.abscessus_ATCC_199 PVAVMTEAAARGDVVAVTDADQDFHEVLVDCSGSPRLRRAMRTLLLETRM
Mvan_3051|M.vanbaalenii_PYR-1 VRAALEQMDASSDVLSLDDAHRAFHAAVVGLAKNRQLDIALEPILLKLQL
MMAR_2244|M.marinum_M ALGRLEQASRGTDSGLIVKSDLDFHAAIIGLLDSPRVDRFFAAIEAEMLY
MAV_0339|M.avium_104 LAAEVVAKSGD---DSIGEANWHFHQMIHRAAHSPRLANQIKHAARVVPT
TH_3342|M.thermoresistible__bu IQDELEEAYTRDDEDRAVRLNHEFHRAINVAADSPKLAQVMSQITRYAPE
. :. : . :
Mb0505|M.bovis_AF2122/97 REHALTGAYD----DADPVLTDLRAINGAVLAGDPAAAAATVEAYLNASA
Rv0494|M.tuberculosis_H37Rv REHALTGAYD----DADPVLTDLRAINGAVLAGDPAAAAATVEAYLNASA
MUL_4564|M.ulcerans_Agy99 REHDLTGAYE----DADPVIADLTAINDAVLAGDPETAAAAVEGYLNASA
Mflv_0016|M.gilvum_PYR-GCK S----VAHTR----HVPVDVCDHGVLLDHIAAGDPDLAARTAGEFLDRII
MSMEG_1317|M.smegmatis_MC2_155 L----VRQIP----DPHAVSDDHHRLVDAIADRDARAAEKLAKDHADRNR
MAB_4411c|M.abscessus_ATCC_199 LLGELQGAYP----DLSEQVREHEVLCAAIGAGDAPAAYRLIDEHMHDAV
Mvan_3051|M.vanbaalenii_PYR-1 PMARNMREEA----RQHAGPGRRHRPGAADEGIGRHKAILSALETNDPAA
MMAR_2244|M.marinum_M ALAILEASEGEYKTDAAKAFGEHKAMYEALRDRDEQRSTQLISEHLRINR
MAV_0339|M.avium_104 NFLTLFPEHE------KHSLDEHAQLLDALGDKDVERARAIAERHVLDAG
TH_3342|M.thermoresistible__bu SVFPTISGWP------ARSTEHHRRVLAALADRDPDGARAAMSEHLAAGA
. :
Mb0505|M.bovis_AF2122/97 LRMVKSYRDRA-------
Rv0494|M.tuberculosis_H37Rv LRMVKSYRDRA-------
MUL_4564|M.ulcerans_Agy99 LRMIMCYRAAYAGEDPER
Mflv_0016|M.gilvum_PYR-GCK NGLGSADSS---------
MSMEG_1317|M.smegmatis_MC2_155 TTTLQTLFGAGTRRSQLG
MAB_4411c|M.abscessus_ATCC_199 TRLMARRDPGSVE-----
Mvan_3051|M.vanbaalenii_PYR-1 VVTAIRDHGHLHYLGLAP
MMAR_2244|M.marinum_M DVLIRIVAS---------
MAV_0339|M.avium_104 RSLAEWLEQRRDGER---
TH_3342|M.thermoresistible__bu GPLIEHLKEHGVIAQ---