For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VSPTPDPQSAVPAREIAYRIVYDAIASGRYLPGQWIREDEVTAEAGVSRTPLREALQRLQSEGLVQLVRH RGALVVGWTSADLDDLFDIRVALETYGARRAAQRRGGAQLESLQKLCASMDEILPAAQEPELQQLGHLCI DFHRGIHEAADNRKLLSVMPMVLAPPFVSEAFHHHTRLELEQAFAHHRELVEAIAIGDEDWAEGVMRAHL RHGRRSLRRMERHLPLMTSHDAEPAVTDTGQPETTSSDPVHE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4042 | - | - | 100% (252) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_1317 | - | 1e-20 | 33.64% (220) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2209 | - | 3e-20 | 30.58% (206) | transcriptional regulator, GntR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 2e-13 | 32.26% (155) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0715 | - | 3e-17 | 30.54% (203) | regulatory protein GntR, HTH |
| M. tuberculosis H37Rv | Rv0165c | - | 2e-13 | 32.26% (155) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0068 | - | 1e-17 | 33.68% (190) | GntR family transcriptional regulator |
| M. marinum M | MMAR_4029 | - | 2e-21 | 35.05% (194) | GntR family transcriptional regulator |
| M. avium 104 | MAV_1576 | - | 3e-20 | 30.09% (226) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3038 | - | 9e-31 | 36.27% (204) | PUTATIVE putative transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3894 | - | 5e-21 | 34.54% (194) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1978 | - | 2e-18 | 31.82% (198) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4042|M.smegmatis_MC2_155 ------------------------------------------------MS
TH_3038|M.thermoresistible__bu ------------------------------------------------MS
MMAR_4029|M.marinum_M -------------------------------------------------M
MUL_3894|M.ulcerans_Agy99 -------------------------------------------------M
MAV_1576|M.avium_104 -------------------------------------------------M
Mvan_1978|M.vanbaalenii_PYR-1 -------------------------------------------------M
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Mflv_0715|M.gilvum_PYR-GCK -----------------------------------MRAADAMNAP--ARA
MAB_0068|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4042|M.smegmatis_MC2_155 PTPDPQSAVPAREIAYRIVYDAIASGRYLPGQWIREDEVTAEAGVSRTPL
TH_3038|M.thermoresistible__bu RTVE--SNGDASERAYQAVLQMILDGEAPAGSWLREQTLAEQIGVSRTPV
MMAR_4029|M.marinum_M TDPEFAARPQLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVTPV
MUL_3894|M.ulcerans_Agy99 TDPEFAARPQLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVTPV
MAV_1576|M.avium_104 SVPDFAARPQLSDDVAHLIRGRIFDGSYAAGSYVRLDQLAAELGISVTPV
Mvan_1978|M.vanbaalenii_PYR-1 SIPEFAARPQLAEDVARFVRRRIFEGTYPAGQYIRLEQLADELGISVTPV
Mb0170c|M.bovis_AF2122/97 RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Rv0165c|M.tuberculosis_H37Rv RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Mflv_0715|M.gilvum_PYR-GCK RTAGAVRREQLSDEVAARLRVEIMTGALRPESFIRLDETAARLGVSITPV
MAB_0068|M.abscessus_ATCC_1997 --MIRTVAISASEEAYRSVKESILNGDIPGGELLSEGEISARMGCSRTPV
: . : * * : : . * * **:
MSMEG_4042|M.smegmatis_MC2_155 REALQRLQSEGLVQLVRHRGALVVGWTSADLDDLFDIRVALETYGARRAA
TH_3038|M.thermoresistible__bu RQALNRLAAEGAIELVPNRGAQVVSFSDEDVEALFDLRARFEPLAVRLAV
MMAR_4029|M.marinum_M REALFALRAEGLVAQQPHRGFVVLPLTKRDLADVAYVQAHVGGELAARAA
MUL_3894|M.ulcerans_Agy99 REALFALRAEGLVAQQPHRGFVVLPLTKRDLADVAYVQAHVGGELAARAA
MAV_1576|M.avium_104 REALFALRAEGLISQQPRRGFVVLPVTRRDVTDVANVQAHVGGELAARAA
Mvan_1978|M.vanbaalenii_PYR-1 REALFGLRAEGLLTQQPRRGFVVLPITRRDIADVADVQAHIGGVLASRAA
Mb0170c|M.bovis_AF2122/97 REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
Rv0165c|M.tuberculosis_H37Rv REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
Mflv_0715|M.gilvum_PYR-GCK REALRTLRGEGMVELEPHRGHRVIPLSRNDIEDIFWLQSTIAQELAATAT
MAB_0068|M.abscessus_ATCC_1997 REAFLRLETEGWLRLYPKRGALVVPITPEERRHVVDARRVIEGAAAARIA
*:*: * ** : .** *: : : : : . . .
MSMEG_4042|M.smegmatis_MC2_155 QRRGGAQLESLQKLCASMDEILPAAQEPELQQLGHLCIDFHRGIHEAADN
TH_3038|M.thermoresistible__bu PQLTEERIAELADLATRMEALLDRRP-LDTHQMSRLNNAFHGIFLAEAGN
MMAR_4029|M.marinum_M INIGAAQLAELQQIQAQLEEAYAADD---DERTVRLNHEFHRAINLAADS
MUL_3894|M.ulcerans_Agy99 INIGAAQLAELQQIQAQLEEAYAADD---DERTVRLNHEFHRAINLAADS
MAV_1576|M.avium_104 VNITDDQLRELKQIQAQLEDAYAGDE---HERTVRLNHEFHRAINIAADS
Mvan_1978|M.vanbaalenii_PYR-1 ERITDEQLQALDHVQDQLEVAYHADD---HEAAVRLNHEFHRGVNVAAGS
Mb0170c|M.bovis_AF2122/97 AHITDVEIDELDRINNALAGAIGSGD---AKTIASIEFAFHRVFNKASRR
Rv0165c|M.tuberculosis_H37Rv AHITDVEIDELDRINNALAGAIGSGD---AKTIASIEFAFHRVFNKASRR
Mflv_0715|M.gilvum_PYR-GCK RRITEEQIEQLSRLNDTLASAVEQHD---VQRIAQAEFEFHRTFNRAAGR
MAB_0068|M.abscessus_ATCC_1997 ER--GAPQSLLSDLSALIEVQLGRAAQGDAAGFAAADVDFHRAIVAKLGN
. * : : ** .
MSMEG_4042|M.smegmatis_MC2_155 RKLLSVMPMVLAPP-FVSEAFHHHTRLELEQAFAHHRELVEAIAIGDEDW
TH_3038|M.thermoresistible__bu RHLTAAMQAVVRPA-LVTLTFQKYSERALRLSMHHHAELVEAARARDPEW
MMAR_4029|M.marinum_M PRLSQLMSQITR---YQPESVFPGIEHWPARAVKDHRRVLVALKKHDDKA
MUL_3894|M.ulcerans_Agy99 PRLSQLMSQITR---YQPESVFPGIEHWPARAVKDHGQVLVALKKHDDKA
MAV_1576|M.avium_104 PKLAQLMSQITR---YAPESVFPAIQGWPEQSMKDHRRILSALKKRDDKL
Mvan_1978|M.vanbaalenii_PYR-1 PKLAQLMGQITK---FALESVYPTVEGWPAHSTRDHRELLAALKARDSEA
Mb0170c|M.bovis_AF2122/97 IKLAWFLLNAAR---YMPAQVFAADPRWGADAVNSHRQLIAALRRRDTAA
Rv0165c|M.tuberculosis_H37Rv IKLAWFLLNAAR---YMGAGVRGRP----AMGRGRGEQSSAADRR---AA
Mflv_0715|M.gilvum_PYR-GCK VKLSWFLLHAAR---YLPPQLFASDDDWGAQAVVSHAELIAALRRGDVDV
MAB_0068|M.abscessus_ATCC_1997 PLLENFYDSLRERQRRMAAAAIGVDPVRVARSVAGHRALVDALAAGDAAR
* . *
MSMEG_4042|M.smegmatis_MC2_155 AEGVMRAHLRHGRRSLRRMERHLPLMTSHDAEPAVTDTGQPETTSSDPVH
TH_3038|M.thermoresistible__bu AEAVMRAHILAARHAGE---------------------------------
MMAR_4029|M.marinum_M ARTAMSEHLASSAVPLIDHLIARGVVAESAPSGSAAERARGG--------
MUL_3894|M.ulcerans_Agy99 ARTAMSEHLASSAVPLIDHLIARGVVAESAPSGSAAERARGG--------
MAV_1576|M.avium_104 ARAAMSEHLAAGAVPLIDHLVARGVVVD----GGGPDPG-----------
Mvan_1978|M.vanbaalenii_PYR-1 ARAAMSEHLCAASGPLIEHLTRRGVIQ-----------------------
Mb0170c|M.bovis_AF2122/97 VIEHTVWQFTDGARRLTEALAETEVFG-----------------------
Rv0165c|M.tuberculosis_H37Rv PPRHSRR---NRAHRLAVHRWGTQADGGPG--------------------
Mflv_0715|M.gilvum_PYR-GCK VVELTRGQFTDGLHRLIAWLEQVGLWS-----------------------
MAB_0068|M.abscessus_ATCC_1997 FSTELVEHMKVVTEVD----------------------------------
MSMEG_4042|M.smegmatis_MC2_155 E
TH_3038|M.thermoresistible__bu -
MMAR_4029|M.marinum_M -
MUL_3894|M.ulcerans_Agy99 -
MAV_1576|M.avium_104 -
Mvan_1978|M.vanbaalenii_PYR-1 -
Mb0170c|M.bovis_AF2122/97 -
Rv0165c|M.tuberculosis_H37Rv -
Mflv_0715|M.gilvum_PYR-GCK -
MAB_0068|M.abscessus_ATCC_1997 -