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SRPYPAGKPKKASPSNMLGDAAPRVVRPAPLRQAVYDAIIEMIIQGTLQRGQHLVEAELAEYLGVSRQPV REALQRLQTDGWIELRPAQGAFVHVPSEEEVDQLLGVRTVLETYSAALAAERATPEDVNRLWELQQDGLN ALTTNNSEGLVEANAALHAAITELAGNQVLADHISLVERKWRWYYLPIARPRGHDAWSEHAELIKAIAAH DVEQATDIMRRHTDRTRQTYHEERMAKAAQA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0166 | - | - | 100% (242) | GntR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1317 | - | 8e-25 | 31.51% (219) | transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4042 | - | 3e-18 | 31.28% (211) | transcriptional regulator, GntR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 7e-12 | 27.35% (234) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0715 | - | 2e-13 | 28.00% (200) | regulatory protein GntR, HTH |
| M. tuberculosis H37Rv | Rv0165c | - | 1e-08 | 25.41% (185) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0068 | - | 2e-18 | 32.49% (197) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0408 | - | 6e-13 | 26.76% (213) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0339 | - | 3e-15 | 31.09% (193) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3038 | - | 3e-19 | 33.84% (198) | PUTATIVE putative transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_1058 | - | 3e-12 | 26.29% (213) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1978 | - | 6e-14 | 27.00% (200) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
MMAR_0408|M.marinum_M -----------------------------------------MNIPLSARR
MUL_1058|M.ulcerans_Agy99 -----------------------------------------MNILLSARR
Mflv_0715|M.gilvum_PYR-GCK -----------------------------------MRAADAMNAPARART
Mvan_1978|M.vanbaalenii_PYR-1 -----------------------------------------MSIPEFA--
MAV_0339|M.avium_104 -----------------------------------------MAAIDIS--
MAB_0068|M.abscessus_ATCC_1997 ----------------------------------------MIRTVAIS--
MSMEG_0166|M.smegmatis_MC2_155 -----------------------------MSRPYPAGKPKKASPSNMLGD
TH_3038|M.thermoresistible__bu -----------------------------------------MSRTVES--
Mb0170c|M.bovis_AF2122/97 RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Rv0165c|M.tuberculosis_H37Rv RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
MMAR_0408|M.marinum_M KSRRPLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITPV
MUL_1058|M.ulcerans_Agy99 ESRRPLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITPV
Mflv_0715|M.gilvum_PYR-GCK AG--AVRREQLSDEVAARLRVEIMTGALRPESFIRLDETAARLGVSITPV
Mvan_1978|M.vanbaalenii_PYR-1 ------ARPQLAEDVARFVRRRIFEGTYPAGQYIRLEQLADELGISVTPV
MAV_0339|M.avium_104 --------GTVRERAARELRDRILTGALPAGSRIDLDAITAEFATSRTPV
MAB_0068|M.abscessus_ATCC_1997 ----------ASEEAYRSVKESILNGDIPGGELLSEGEISARMGCSRTPV
MSMEG_0166|M.smegmatis_MC2_155 AAPRVVRPAPLRQAVYDAIIEMIIQGTLQRGQHLVEAELAEYLGVSRQPV
TH_3038|M.thermoresistible__bu -------NGDASERAYQAVLQMILDGEAPAGSWLREQTLAEQIGVSRTPV
: . : *: * : : :. * **
Mb0170c|M.bovis_AF2122/97 REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
Rv0165c|M.tuberculosis_H37Rv REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
MMAR_0408|M.marinum_M REALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAVTAT
MUL_1058|M.ulcerans_Agy99 REALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAVTAT
Mflv_0715|M.gilvum_PYR-GCK REALRTLRGEGMVELEPHRGHRVIPLSRNDIEDIFWLQSTIAQELAATAT
Mvan_1978|M.vanbaalenii_PYR-1 REALFGLRAEGLLTQQPRRGFVVLPITRRDIADVADVQAHIGGVLASRAA
MAV_0339|M.avium_104 REALLELSFEGLVQVAPRSGVTVIGISPEDVLDSFTILGVLTGQAAAWAA
MAB_0068|M.abscessus_ATCC_1997 REAFLRLETEGWLRLYPKRGALVVPITPEERRHVVDARRVIEGAAAARIA
MSMEG_0166|M.smegmatis_MC2_155 REALQRLQTDGWIELRPAQGAFVHVPSEEEVDQLLGVRTVLETYSAALAA
TH_3038|M.thermoresistible__bu RQALNRLAAEGAIELVPNRGAQVVSFSDEDVEALFDLRARFEPLAVRLAV
*:*: * :* : * * * : .: : . .
Mb0170c|M.bovis_AF2122/97 AH-ITDVEIDELDRINNALAGAIGSG--DAKTIASIEFAFHRVFNKASRR
Rv0165c|M.tuberculosis_H37Rv AH-ITDVEIDELDRINNALAGAIGSG--DAKTIASIEFAFHRVFNKASRR
MMAR_0408|M.marinum_M ER-ISEIDIGELEHINDALTAAVGAG--DTEAIAALEFAFHRVLNQSSGR
MUL_1058|M.ulcerans_Agy99 ER-ISEVVIGELEHINDALTAAVGAG--DTEAIAALEFAFHRVLNQSSGR
Mflv_0715|M.gilvum_PYR-GCK RR-ITEEQIEQLSRLNDTLASAVEQH--DVQRIAQAEFEFHRTFNRAAGR
Mvan_1978|M.vanbaalenii_PYR-1 ER-ITDEQLQALDHVQDQLEVAYHAD--DHEAAVRLNHEFHRGVNVAAGS
MAV_0339|M.avium_104 ER-IGPEELATLRELAAEVVAKSGD-----DSIGEANWHFHQMIHRAAHS
MAB_0068|M.abscessus_ATCC_1997 ERGAPQSLLSDLSALIEVQLGRAAQG--DAAGFAAADVDFHRAIVAKLGN
MSMEG_0166|M.smegmatis_MC2_155 ER-ATPEDVNRLWELQQDGLNALTTN--NSEGLVEANAALHAAITELAGN
TH_3038|M.thermoresistible__bu PQ-LTEERIAELADLATRMEALLDRRPLDTHQMSRLNNAFHGIFLAEAGN
: : * : : :* .
Mb0170c|M.bovis_AF2122/97 IKLAWF---LLNAAR--YMPAQVFAADPRWGADAVNSHRQLIAALRRRDT
Rv0165c|M.tuberculosis_H37Rv IKLAWF---LLNAAR--YMGAGVRGRP----AMGRGRGEQSSAADRR---
MMAR_0408|M.marinum_M IKLAWF---LLNAAR--YMPAQLYASDPQWGAAAVDNHRQLIAALRRRDT
MUL_1058|M.ulcerans_Agy99 IKLAWF---LLNAAR--YMPAQLYASDPQWGAAAVDNHRQLIAALRRRDT
Mflv_0715|M.gilvum_PYR-GCK VKLSWF---LLHAAR--YLPPQLFASDDDWGAQAVVSHAELIAALRRGDV
Mvan_1978|M.vanbaalenii_PYR-1 PKLAQL---MGQITK--FALESVYPTVEGWPAHSTRDHRELLAALKARDS
MAV_0339|M.avium_104 PRLANQ---IKHAAR--VVPTNFLTLFPEHEKHSLDEHAQLLDALGDKDV
MAB_0068|M.abscessus_ATCC_1997 PLLENFYDSLRERQR--RMAAAAIGVDPVRVARSVAGHRALVDALAAGDA
MSMEG_0166|M.smegmatis_MC2_155 QVLADH---ISLVER--KWRWYYLPIARPRGHDAWSEHAELIKAIAAHDV
TH_3038|M.thermoresistible__bu RHLTAA---MQAVVRPALVTLTFQKYSERALRLSMHHHAELVEAARARDP
* : : . *
Mb0170c|M.bovis_AF2122/97 AAVIEHTVWQFTDGARRLTEALAETEVFG---
Rv0165c|M.tuberculosis_H37Rv AAPPRHSRR---NRAHRLAVHRWGTQADGGPG
MMAR_0408|M.marinum_M AAVIEHSVWQFTDAAHRLTQMLETNGIFN---
MUL_1058|M.ulcerans_Agy99 AAVIEHSVWQFTDAAHRLTQMLETNGIFN---
Mflv_0715|M.gilvum_PYR-GCK DVVVELTRGQFTDGLHRLIAWLEQVGLWS---
Mvan_1978|M.vanbaalenii_PYR-1 EAARAAMSEHLCAASGPLIEHLTRRGVIQ---
MAV_0339|M.avium_104 ERARAIAERHVLDAGRSLAEWLEQRRDGER--
MAB_0068|M.abscessus_ATCC_1997 ARFST-----------ELVEHMKVVTEVD---
MSMEG_0166|M.smegmatis_MC2_155 EQATDIMRRHTDRTRQTYHEERMAKAAQA---
TH_3038|M.thermoresistible__bu EWAEAVMRAHILAARHAGE-------------