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AAIDISGTVRERAARELRDRILTGALPAGSRIDLDAITAEFATSRTPVREALLELSFEGLVQVAPRSGVT VIGISPEDVLDSFTILGVLTGQAAAWAAERIGPEELATLRELAAEVVAKSGDDSIGEANWHFHQMIHRAA HSPRLANQIKHAARVVPTNFLTLFPEHEKHSLDEHAQLLDALGDKDVERARAIAERHVLDAGRSLAEWLE QRRDGER*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0339 | - | - | 100% (218) | transcriptional regulator, GntR family protein |
| M. avium 104 | MAV_1576 | - | 8e-24 | 33.66% (202) | transcriptional regulator, GntR family protein |
| M. avium 104 | MAV_5020 | - | 8e-21 | 32.96% (179) | transcriptional regulator, GntR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 4e-19 | 29.41% (204) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0715 | - | 6e-23 | 33.82% (204) | regulatory protein GntR, HTH |
| M. tuberculosis H37Rv | Rv0165c | - | 1e-14 | 31.97% (147) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4571 | - | 7e-23 | 33.33% (201) | GntR family transcriptional regulatory protein |
| M. marinum M | MMAR_4029 | - | 3e-22 | 33.66% (202) | GntR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6639 | - | 2e-93 | 80.00% (215) | transcriptional regulator, GntR family protein, putative |
| M. thermoresistible (build 8) | TH_3342 | - | 1e-24 | 32.84% (204) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3894 | - | 6e-23 | 34.16% (202) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0130 | - | 7e-25 | 33.79% (219) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Mflv_0715|M.gilvum_PYR-GCK -----------------------------------MRAADAMNAP--ARA
Mvan_0130|M.vanbaalenii_PYR-1 -----------------------------------------MNAP--ART
MAB_4571|M.abscessus_ATCC_1997 -----------------------------------------MNAP---RA
MMAR_4029|M.marinum_M -------------------------------------------------M
MUL_3894|M.ulcerans_Agy99 -------------------------------------------------M
TH_3342|M.thermoresistible__bu -------------------------------------------------V
MAV_0339|M.avium_104 --------------------------------------------------
MSMEG_6639|M.smegmatis_MC2_155 --------------------------------------------------
Mb0170c|M.bovis_AF2122/97 RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Rv0165c|M.tuberculosis_H37Rv RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Mflv_0715|M.gilvum_PYR-GCK RTAGAVRREQLSDEVAARLRVEIMTGALRPESFIRLDETAARLGVSITPV
Mvan_0130|M.vanbaalenii_PYR-1 PVAGAVRREQLSDEVAARLRAEIMTGALRPDSFIRLDETAARLGVSITPV
MAB_4571|M.abscessus_ATCC_1997 RTR-EIRRPQLSEEVAGRLRAAIMTGDLRPGEYIRMDETAAQLGVSVTPV
MMAR_4029|M.marinum_M TDPEFAARPQLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVTPV
MUL_3894|M.ulcerans_Agy99 TDPEFAARPQLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVTPV
TH_3342|M.thermoresistible__bu AVPEFAARPQLAEDVARYVRRRIFDGTYAAGEYVRLDQLAVELGVSVTPV
MAV_0339|M.avium_104 -MAAIDISGTVRERAARELRDRILTGALPAGSRIDLDAITAEFATSRTPV
MSMEG_6639|M.smegmatis_MC2_155 -MVGMDIGGTVRERAARELRDRILTGALPAGTRIDLDAITAEFATSRTPV
: : .* :* * * . : :* :..:. * ***
Mb0170c|M.bovis_AF2122/97 REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
Rv0165c|M.tuberculosis_H37Rv REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
Mflv_0715|M.gilvum_PYR-GCK REALRTLRGEGMVELEPHRGHRVIPLSRNDIEDIFWLQSTIAQELAATAT
Mvan_0130|M.vanbaalenii_PYR-1 REALRTLRGEGMVELEPHRGHRVVPLTRTDIEDIFWLQSTIAQELAATAA
MAB_4571|M.abscessus_ATCC_1997 REALLTLRGEGMVDAVPHRGYAVAALSRKDVEDIFALQSHLAVELAKAAA
MMAR_4029|M.marinum_M REALFALRAEGLVAQQPHRGFVVLPLTKRDLADVAYVQAHVGGELAARAA
MUL_3894|M.ulcerans_Agy99 REALFALRAEGLVAQQPHRGFVVLPLTKRDLADVAYVQAHVGGELAARAA
TH_3342|M.thermoresistible__bu REALFQLRAEGLLVQQPRRGFMVLPVTERDLTDIANVQAHVGGELAARAA
MAV_0339|M.avium_104 REALLELSFEGLVQVAPRSGVTVIGISPEDVLDSFTILGVLTGQAAAWAA
MSMEG_6639|M.smegmatis_MC2_155 REALLELSFEGLVRVAPRSGITVIGISSADVLDSFTILGVLTGQAAAWAA
**** * **:: *: * * :: *: * : . : : * *:
Mb0170c|M.bovis_AF2122/97 AHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIKL
Rv0165c|M.tuberculosis_H37Rv AHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIKL
Mflv_0715|M.gilvum_PYR-GCK RRITEEQIEQLSRLNDTLASAVEQHDVQRIAQAEFEFHRTFNRAAGRVKL
Mvan_0130|M.vanbaalenii_PYR-1 RNITDAQIDELAQLNERLAEAVEQRDPDRVARAEFTFHRAFNRAGGRIKL
MAB_4571|M.abscessus_ATCC_1997 ARITPEQADALAELNDALRNATS---PDQVIWAEFEFHRLLNHVADRPKL
MMAR_4029|M.marinum_M INIGAAQLAELQQIQAQLEEAYAADDDERTVRLNHEFHRAINLAADSPRL
MUL_3894|M.ulcerans_Agy99 INIGAAQLAELQQIQAQLEEAYAADDDERTVRLNHEFHRAINLAADSPRL
TH_3342|M.thermoresistible__bu QNITDEQLRVLTAIQDELEEAYTRDDEDRAVRLNHEFHRAINVAADSPKL
MAV_0339|M.avium_104 ERIGPEELATLRELAAEVVAKSG---DDSIGEANWHFHQMIHRAAHSPRL
MSMEG_6639|M.smegmatis_MC2_155 ERVTDEELDQLRALAAGVAEHSG---DDAIGEANWRFHQAIHRAAHSPRL
.: : * : : . : **: :: .. :*
Mb0170c|M.bovis_AF2122/97 AWFLLNAARYMPAQVFAADPRWGADAVNSHRQLIAALRRRDTAAVIEHTV
Rv0165c|M.tuberculosis_H37Rv AWFLLNAARYMGAGVRGRP----AMGRGRGEQSSAADRR---AAPPRHSR
Mflv_0715|M.gilvum_PYR-GCK SWFLLHAARYLPPQLFASDDDWGAQAVVSHAELIAALRRGDVDVVVELTR
Mvan_0130|M.vanbaalenii_PYR-1 AWFLLHAARYLPPQLFASDETWGPVAVASHAELIEALRRRDVDTVVELTR
MAB_4571|M.abscessus_ATCC_1997 AWFLLQAVRYTPHQLFAEDASWIVPTTETHDKLIAALRAGDIAEVIAQTE
MMAR_4029|M.marinum_M SQLMSQITRYQPESVFPGIEHWPARAVKDHRRVLVALKKHDDKAARTAMS
MUL_3894|M.ulcerans_Agy99 SQLMSQITRYQPESVFPGIEHWPARAVKDHGQVLVALKKHDDKAARTAMS
TH_3342|M.thermoresistible__bu AQVMSQITRYAPESVFPTISGWPARSTEHHRRVLAALADRDPDGARAAMS
MAV_0339|M.avium_104 ANQIKHAARVVPTNFLTLFPEHEKHSLDEHAQLLDALGDKDVERARAIAE
MSMEG_6639|M.smegmatis_MC2_155 LAAIKQAARVVPTNFLVLFPEHEKHSLSEHEELLDALEKRDADHARVIAE
: : .* . . *
Mb0170c|M.bovis_AF2122/97 WQFTDGARRLTEALAETEVFG---------------
Rv0165c|M.tuberculosis_H37Rv R---NRAHRLAVHRWGTQADGGPG------------
Mflv_0715|M.gilvum_PYR-GCK GQFTDGLHRLIAWLEQVGLWS---------------
Mvan_0130|M.vanbaalenii_PYR-1 GQFTDGRARLIAWLEQVGLWS---------------
MAB_4571|M.abscessus_ATCC_1997 VQFIDGARRLIEYLDRTGMWSQD-------------
MMAR_4029|M.marinum_M EHLASSAVPLIDHLIARGVVAESAPSGSAAERARGG
MUL_3894|M.ulcerans_Agy99 EHLASSAVPLIDHLIARGVVAESAPSGSAAERARGG
TH_3342|M.thermoresistible__bu EHLAAGAGPLIEHLKEHGVIAQ--------------
MAV_0339|M.avium_104 RHVLDAGRSLAEWLEQRRDGER--------------
MSMEG_6639|M.smegmatis_MC2_155 HHVLEAGRSLADWLDRRNDHRSGSLPTAR-------
*