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MAAPTEEPSRLALPATLVEVAGNRLRDAILSGELAPGEKIIEEQLCADFGISRAPLREALRRLAQQGLVE HLPRRGSRVTEWSPTDILQLFELRNVLERHAIESALPLADLDRDLEPVRAALEQMDASSDVLSLDDAHRA FHAAVVGLAKNRQLDIALEPILLKLQLPMARNMREEARQHAGPGRRHRPGAADEGIGRHKAILSALETND PAAVVTAIRDHGHLHYLGLAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3051 | - | - | 100% (231) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0931 | - | 3e-12 | 28.64% (213) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0130 | - | 3e-11 | 33.77% (151) | GntR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 2e-11 | 27.98% (218) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0715 | - | 5e-11 | 34.09% (132) | regulatory protein GntR, HTH |
| M. tuberculosis H37Rv | Rv0165c | - | 1e-11 | 32.14% (196) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4411c | - | 9e-21 | 32.08% (212) | GntR family transcriptional regulator |
| M. marinum M | MMAR_2244 | - | 1e-16 | 27.23% (224) | GntR family transcriptional regulator |
| M. avium 104 | MAV_0339 | - | 7e-13 | 33.80% (142) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_1317 | - | 3e-19 | 29.15% (223) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_3038 | - | 1e-15 | 33.54% (164) | PUTATIVE putative transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_1833 | - | 1e-16 | 27.23% (224) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2244|M.marinum_M ---------------------------------MLEEEAVVIPRADSPDQ
MUL_1833|M.ulcerans_Agy99 ---------------------------------MLEEEAVVIPRADSPDQ
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Mflv_0715|M.gilvum_PYR-GCK -----------------------------------MRAADAMNAP--ARA
MAV_0339|M.avium_104 --------------------------------------------------
Mvan_3051|M.vanbaalenii_PYR-1 --------------------------------------------MAAPTE
MAB_4411c|M.abscessus_ATCC_199 --------------------------------------------MTTLVP
MSMEG_1317|M.smegmatis_MC2_155 --------------------------------------------MSSTPS
TH_3038|M.thermoresistible__bu --------------------------------------------------
MMAR_2244|M.marinum_M TCGRLPARGTIGEQVADLIQESILSGEAKRGAPLREELIADRYQVSRRTV
MUL_1833|M.ulcerans_Agy99 TCGRLPARGTVGEQVADLIQESILSGEAKRGSPLREELIADRYQVSRRTV
Mb0170c|M.bovis_AF2122/97 RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Rv0165c|M.tuberculosis_H37Rv RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Mflv_0715|M.gilvum_PYR-GCK RTAGAVRREQLSDEVAARLRVEIMTGALRPESFIRLDETAARLGVSITPV
MAV_0339|M.avium_104 -MAAIDISGTVRERAARELRDRILTGALPAGSRIDLDAITAEFATSRTPV
Mvan_3051|M.vanbaalenii_PYR-1 EPSRLALPATLVEVAGNRLRDAILSGELAPGEKIIEEQLCADFGISRAPL
MAB_4411c|M.abscessus_ATCC_199 EEFAPLERQSTAELIAERLRIAIMRGVLAPGAQLGEASLAAQFAVSRGPL
MSMEG_1317|M.smegmatis_MC2_155 ADEGSPSNLMLRGRLIDALRSDVIRGRYPPGYRLVERDVADAYGVSRLPA
TH_3038|M.thermoresistible__bu MSRTVESNGDASERAYQAVLQMILDGEAPAGSWLREQTLAEQIGVSRTPV
: :: * : * .
MMAR_2244|M.marinum_M RDALRVLESNGLVRHQRHKGSTVVDFSAEDITDMYRSREVLELDAAKRWC
MUL_1833|M.ulcerans_Agy99 RDALRVLESNGLVRHQRHKGSTVVDFSAGDITDMYRSREVLELDAAKRWC
Mb0170c|M.bovis_AF2122/97 REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELAT---
Rv0165c|M.tuberculosis_H37Rv REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELAT---
Mflv_0715|M.gilvum_PYR-GCK REALRTLRGEGMVELEPHRGHRVIPLSRNDIEDIFWLQSTIAQELAA---
MAV_0339|M.avium_104 REALLELSFEGLVQVAPRSGVTVIGISPEDVLDSFTILGVLTGQAAA---
Mvan_3051|M.vanbaalenii_PYR-1 REALRRLAQQGLVEHLPRRGSRVTEWSPTDILQLFELRNVLERHAIE---
MAB_4411c|M.abscessus_ATCC_199 REAMQRLVSEGLLRSERNRGIFVIELTDDDVLDVYRSRSAIERAALE---
MSMEG_1317|M.smegmatis_MC2_155 REALQALKTEGFLEVRKTRGLVVRGWTERDVTELFDIRQALEAMACR---
TH_3038|M.thermoresistible__bu RQALNRLAAEGAIELVPNRGAQVVSFSDEDVEALFDLRARFEPLAVR---
*:*: * :* : * * : *: : :
MMAR_2244|M.marinum_M RAGEVDSGYRFHRLTEALGRLEQASRGT--DSGLIVKSDLDFHAAIIGLL
MUL_1833|M.ulcerans_Agy99 RAGEVDSGYRFHRLTEALGRLEQASRGT--DSGLIVKSDLDFHAAIIGLL
Mb0170c|M.bovis_AF2122/97 SATAHITDVEIDELDRINNALAGAIGSG--DAKTIASIEFAFHRVFN--K
Rv0165c|M.tuberculosis_H37Rv SATAHITDVEIDELDRINNALAGAIGSG--DAKTIASIEFAFHRVFN--K
Mflv_0715|M.gilvum_PYR-GCK TATRRITEEQIEQLSRLNDTLASAVEQH--DVQRIAQAEFEFHRTFN--R
MAV_0339|M.avium_104 WAAERIGPEELATLRELAAEVVAKSGD-----DSIGEANWHFHQMIH--R
Mvan_3051|M.vanbaalenii_PYR-1 --SALPLADLDRDLEPVRAALEQMDASS--DVLSLDDAHRAFHAAVVGLA
MAB_4411c|M.abscessus_ATCC_199 CIMTGDTVTAYRRLLVPVAVMTEAAARG--DVVAVTDADQDFHEVLVDCS
MSMEG_1317|M.smegmatis_MC2_155 EAAENRTDEDIAALRGAAESADRAAERN--DVTAAHDANALFHQLLVTAS
TH_3038|M.thermoresistible__bu LAVPQLTEERIAELADLATRMEALLDRRPLDTHQMSRLNNAFHGIFLAEA
* . ** .
MMAR_2244|M.marinum_M DSPRVDRFFAAIEAEMLYALAILEASEGEYKTDAAKAFGEHKAMYEALRD
MUL_1833|M.ulcerans_Agy99 DSPRVDRFFAAIEAEMLYALAILEASEGEYKTDAAKAFGEHKAMYEALRD
Mb0170c|M.bovis_AF2122/97 ASRRIKLAWFLLNAARYMPAQVFAADP----RWGADAVNSHRQLIAALRR
Rv0165c|M.tuberculosis_H37Rv ASRRIKLAWFLLNAARYMGAGVRGRP--------AMGRGRGEQSSAADRR
Mflv_0715|M.gilvum_PYR-GCK AAGRVKLSWFLLHAARYLPPQLFASDD----DWGAQAVVSHAELIAALRR
MAV_0339|M.avium_104 AAHSPRLANQIKHAARVVPTNFLTLFP----EHEKHSLDEHAQLLDALGD
Mvan_3051|M.vanbaalenii_PYR-1 KNRQLDIALEPILLKLQLPMARNMREE------ARQHAGPGRRHRPGAAD
MAB_4411c|M.abscessus_ATCC_199 GSPRLRRAMRTLLLETRMLLGELQGAYP----DLSEQVREHEVLCAAIGA
MSMEG_1317|M.smegmatis_MC2_155 HNRTLGEIMAPILYRVQWLVRQIPDPH--------AVSDDHHRLVDAIAD
TH_3038|M.thermoresistible__bu GNRHLTAAMQAVVRPALVTLTFQKYSER----ALRLSMHHHAELVEAARA
.
MMAR_2244|M.marinum_M RDEQRSTQLISEHLRINRDVLIRIVAS-----------
MUL_1833|M.ulcerans_Agy99 RDEQRSTQLISEHLRINRDVLIRIVAS-----------
Mb0170c|M.bovis_AF2122/97 RDTAAVIEHTVWQFTDGARRLTEALAETEVFG------
Rv0165c|M.tuberculosis_H37Rv ---AAPPRHSRR---NRAHRLAVHRWGTQADGGPG---
Mflv_0715|M.gilvum_PYR-GCK GDVDVVVELTRGQFTDGLHRLIAWLEQVGLWS------
MAV_0339|M.avium_104 KDVERARAIAERHVLDAGRSLAEWLEQRRDGER-----
Mvan_3051|M.vanbaalenii_PYR-1 EGIGRHKAILSALETNDPAAVVTAIRDHGHLHYLGLAP
MAB_4411c|M.abscessus_ATCC_199 GDAPAAYRLIDEHMHDAVTRLMARRDPGSVE-------
MSMEG_1317|M.smegmatis_MC2_155 RDARAAEKLAKDHADRNRTTTLQTLFGAGTRRSQLG--
TH_3038|M.thermoresistible__bu RDPEWAEAVMRAHILAARHAGE----------------