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TPVRPYRGIEAADRLAQRRGQLLAAGLDLLGDENAEVTVRAVCQRAGLAARYFYESFGDKDAFVSEVYDW VIAEIAASTQAAVASVPLAEQTTAAMTNIVRTIADDPRIGRLLFSAKLSNEVVVRKRVEGIGFFAGLLGQ HTVDALRLPENDQLRATAHFAVGGVTQTISAWLGGEVSFTPDELVQQLRSLLDALANLQSRK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0612 | - | - | 100% (203) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5768 | - | 4e-21 | 34.81% (181) | hypothetical protein MSMEG_5768 |
| M. smegmatis MC2 155 | MSMEG_1168 | - | 5e-19 | 32.47% (194) | putative transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0281c | - | 2e-67 | 62.94% (197) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0331 | - | 1e-59 | 58.88% (197) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0275c | - | 1e-66 | 62.44% (197) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2494c | - | 5e-44 | 45.55% (191) | putative transcriptional regulator |
| M. marinum M | MMAR_0536 | - | 2e-62 | 59.09% (198) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4882 | - | 1e-69 | 67.35% (196) | FadD27 protein |
| M. thermoresistible (build 8) | TH_0801 | fadD27 | 1e-64 | 60.41% (197) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY |
| M. ulcerans Agy99 | MUL_1200 | - | 2e-62 | 59.09% (198) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0409 | - | 2e-52 | 61.01% (159) | FadD27 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0281c|M.bovis_AF2122/97 ----MTRSD--RPYRGVEAAERLATRRRQLLSAGLDLLGSDQHDIAELTI
Rv0275c|M.tuberculosis_H37Rv ----MTRSD--RPYRGVEAAERLATRRRQSLSAGLDLLGSDQHDIAELTI
MAV_4882|M.avium_104 -MVCMSQTSGARPYRGVEAAERLATRRNRLLGAGLDLLGAEQQNIAAVTV
MMAR_0536|M.marinum_M ----------MRPYRGVEATERLAARRSQLLESGLELLGSSDRDIAELTV
MUL_1200|M.ulcerans_Agy99 ----------MRPYRGVEATERLATRRSQLLESGLELLGSSDRDIAELTV
Mflv_0331|M.gilvum_PYR-GCK MGCMA----QVRPYRGVDAPARVAERRRRLLEAGLDLLGG-QLNPPELTV
Mvan_0409|M.vanbaalenii_PYR-1 -------------------------------------------------M
TH_0801|M.thermoresistible__bu MGSMASPNRQVRPYRGVDPAERRAQRRRRLLEAGLELLGGEQRDPAELTV
MSMEG_0612|M.smegmatis_MC2_155 -------MTPVRPYRGIEAADRLAQRRGQLLAAGLDLLGD---ENAEVTV
MAB_2494c|M.abscessus_ATCC_199 -----MSSPAGRSYSGLPADERLARRRQRLLEVGLDILGTPD-GSGDLTL
:
Mb0281c|M.bovis_AF2122/97 RTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAVPAR
Rv0275c|M.tuberculosis_H37Rv RTICRRAGLSVRYFYESFTDKDEFVGRVFDWVVAELVATTQAAVTAVPAR
MAV_4882|M.avium_104 RGVCRRAGLAARYFYESFTDKDQFVACVFDWVVAELAATTQAAVTAVPAH
MMAR_0536|M.marinum_M RGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDLATTIQAAVATVPPP
MUL_1200|M.ulcerans_Agy99 RGICRQAGLSARYFYESFPDKDEFIGGVFDWVVGDLATTIQAAVATVPPP
Mflv_0331|M.gilvum_PYR-GCK RAICAQSGLAARYFYESFTDKDVFVGAVFDRVIADIATTTQAAVAAAPPR
Mvan_0409|M.vanbaalenii_PYR-1 RAICAQSGLAARYFYESFADKDVFVGAVFDWVVADIAATTQAAVAAAPVR
TH_0801|M.thermoresistible__bu RAICREAGLTMRYFYESFTDKDDFVSAVFDWVVSDIAATTQAAVAAAPRR
MSMEG_0612|M.smegmatis_MC2_155 RAVCQRAGLAARYFYESFGDKDAFVSEVYDWVIAEIAASTQAAVASVPLA
MAB_2494c|M.abscessus_ATCC_199 RTVCQRSGLAQRYFYESFADKDEYAAAIFDWAIEGLAATVEAEVAAAHPR
* :* .:**: ******* *** : . ::* .: :.:: :* *::.
Mb0281c|M.bovis_AF2122/97 EQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESSALFAMLSG
Rv0275c|M.tuberculosis_H37Rv EQTRAGMANIVRTITADARVGRLLFSTQLANAVITRKRAESSALFAMLSG
MAV_4882|M.avium_104 EQTRAGMANIVRTITEDARVGRLLFSTQLADPVVVRKRAESSALFAMLSG
MMAR_0536|M.marinum_M EQARAGIAEIVRTIVGDARIGRLLFSTHLANPVVVRKRTESSALFAMLSG
MUL_1200|M.ulcerans_Agy99 EQARAGIAEIVRTIVGDARIGRLLFSTHLANPVVVRKRTESSALFAMLSG
Mflv_0331|M.gilvum_PYR-GCK EQSRQGMANIVRAISEDARVGRLLFNAHLDNPVVVRKRAESGALFALLSG
Mvan_0409|M.vanbaalenii_PYR-1 EQSRQGMANIVNTISDDIRVGRLLFNTRLDNPVVVRKRAESGALFALLSG
TH_0801|M.thermoresistible__bu DQTRAGMANIVRTVSEDPRVGRLLFSRHLSTATVVRKRAESGALFAMLSG
MSMEG_0612|M.smegmatis_MC2_155 EQTTAAMTNIVRTIADDPRIGRLLFSAKLSNEVVVRKRVEGIGFFAGLLG
MAB_2494c|M.abscessus_ATCC_199 LQVRAGITSVVRAVSADRRIGQLLYSRHQVNPVLVRRRFDATAMFVSLFA
* .::.:*.:: * *:*:**:. : .:.*:* :. .:*. * .
Mb0281c|M.bovis_AF2122/97 QHAVDTLHAPANDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQLVDQLA
Rv0275c|M.tuberculosis_H37Rv QHAVDTLHAPANDHVKAVAHFAVGGVGQTISAWLAGDVRLDPDQLVDQLA
MAV_4882|M.avium_104 QHVGDALRMPANDRIKAAAHFVVGGVAQTISAWLAGEVRLEPDQLVDQLA
MMAR_0536|M.marinum_M QHAGDALRIPANDRIKVGAHFIVGGVAQTISAWIEGDVELEPGQLVDQLA
MUL_1200|M.ulcerans_Agy99 QHAGDALRIPANDRIKVGAHFIVGGVAQTISAWIEGDVELEPGQLVDQLA
Mflv_0331|M.gilvum_PYR-GCK QHAGSALRLERNDRITSAAHFVVGGVAQTLSAWLAGDLTFTEAQLAAQLG
Mvan_0409|M.vanbaalenii_PYR-1 QHAGTALQVEPNERIRAAAHFAVGGVAQTLSAWLAGDLAFTPEQLAGQLG
TH_0801|M.thermoresistible__bu QHVGSTMQLPENERIKATSHFVVGGVGQTIGAWLAGEVRLSPEALIDQLA
MSMEG_0612|M.smegmatis_MC2_155 QHTVDALRLPENDQLRATAHFAVGGVTQTISAWLGGEVSFTPDELVQQLR
MAB_2494c|M.abscessus_ATCC_199 QHLHDWFRRDDQGNLPVLAHFIVGGVGQAVTAWLHQEVTISEDELIEQLV
** :: : .: :** **** *:: **: :: : * **
Mb0281c|M.bovis_AF2122/97 ALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSSARPARRS
Rv0275c|M.tuberculosis_H37Rv ALLDELTDPNLSRPRVAATAAKSGANDPQPPEVAGQPPSSARPARRS
MAV_4882|M.avium_104 ALLDELAEPALYRR--TETPAQS------------------------
MMAR_0536|M.marinum_M SLLDELSDPRLYGLRGTRAGATAASPAQ-------------------
MUL_1200|M.ulcerans_Agy99 SLLDELSDPRLYGLRGTRAGATAASPAQ-------------------
Mflv_0331|M.gilvum_PYR-GCK ALIDQLADPALYRD---------------------------------
Mvan_0409|M.vanbaalenii_PYR-1 ALLDQLADPTLYRD---------------------------------
TH_0801|M.thermoresistible__bu SVIDQLAKPELFRAD--------------------------------
MSMEG_0612|M.smegmatis_MC2_155 SLLDALANLQSRK----------------------------------
MAB_2494c|M.abscessus_ATCC_199 DMLLAHGPAGSGQR---------------------------------
::