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VVGFGRIDGGPRSAIVVGAGTVGLSAAWFLQERGVAVTVVDRVGVGTGASWGNAGWIAPALTIPANSPAM LRDGLRSLFDSQAPLHIPLAADSELANFLIQFAANCRRASWKRAMRANVPLNEESLEAFDVLFANGVDAP LTDAPITALFSTTAEAERMMRDLRALEDAGQTVSVSGLSGQQLREQVPLTSPAVAAALNVNGQRYVDPGR FVQALRRAVEERGATMRTMEVSDVLSSGNGVQVYPRIGKWLTADVAVVATGAWLPRLAGSRITVPVQAAR RYSFTVPVDRPIPTPIYLPEAGIACTPHKGALRVTGATELRDPYEPAMPSRVGAMVAAAEPLLEGVRWAE RSDIWVGPGALTPDGRPLIGEMSRGVYLAGGHGMWGLAHGPVTGRLLAEYITTGKQPEALRPFDPLRRTG ADP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1129 | - | - | 100% (423) | D-amino-acid dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6291 | - | e-154 | 63.31% (417) | D-amino-acid dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0175 | - | 1e-07 | 23.21% (418) | FAD dependent oxidoreductase, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0807 | - | 3e-05 | 33.90% (118) | hypothetical protein Mb0807 |
| M. gilvum PYR-GCK | Mflv_0955 | - | 7e-91 | 44.34% (415) | D-amino-acid dehydrogenase |
| M. tuberculosis H37Rv | Rv0785 | - | 3e-05 | 33.90% (118) | putative FAD-binding dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4421 | solA | 2e-05 | 26.34% (243) | dehydrogenase |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2138 | - | 1e-147 | 61.65% (412) | D-amino-acid dehydrogenase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_4780 | - | 1e-148 | 61.00% (418) | D-amino-acid dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0807|M.bovis_AF2122/97 MALTCTDMSDAVAGSDAEGLTADAIVVGAGLAGLVAACELADRGLRVLIL
Rv0785|M.tuberculosis_H37Rv MALTCTDMSDAVAGSDAEGLTADAIVVGAGLAGLVAACELADRGLRVLIL
MSMEG_1129|M.smegmatis_MC2_155 --------MVG--FGRIDGGPRSAIVVGAGTVGLSAAWFLQERGVAVTVV
Mvan_4780|M.vanbaalenii_PYR-1 --------MSG--GSGMDGGPRSVIVVGAGIVGLSTAWFLQERGVDVTVV
TH_2138|M.thermoresistible__bu --------MSQRFAERVDGGPRSAIVIGAGIVGLSTAWFLQERGVDVCVV
Mflv_0955|M.gilvum_PYR-GCK --------MES-MSERSGGRPQRVVVVGAGMVGLSTAWYLQEHGVEVTVV
MMAR_4421|M.marinum_M ----------------MATTGYDVIVIGLGGMGSAAAYHLAARGRRVLGL
.:*:* * * :* * :* * :
Mb0807|M.bovis_AF2122/97 DQE---NRANVGGQAFWSFGGLFLVNSPEQRRLGIRDSHELALQDWLGTA
Rv0785|M.tuberculosis_H37Rv DQE---NRANVGGQAFWSFGGLFLVNSPEQRRLGIRDSHELALQDWLGTA
MSMEG_1129|M.smegmatis_MC2_155 DRVGVGTGASWGNAGWIAPALTIPANSPAMLRDGLRSLFDSQAPLHIPLA
Mvan_4780|M.vanbaalenii_PYR-1 DRSGVAAGASWGNAGWVSPALTAPLNSPSVLREGLRALADPAAPLHIPVR
TH_2138|M.thermoresistible__bu DRTGVAAGASWGNAGWISPGLAIPLNEPGVLRYGLRNLLSPTAPLHLPLT
Mflv_0955|M.gilvum_PYR-GCK DSDGVAAGSSWGNAGWLTPSIATPLPEPAVLRYGVRALLSPSSPVYVPLT
MMAR_4421|M.marinum_M ERHQPAHDKGSSHGGSRIIRQSYFED-PGYVPLLLRSYELWERLAIDAQS
: . . . * :*
Mb0807|M.bovis_AF2122/97 AFDRPEDYWPEQWAHAYVDFAAGEKRS--WLRARGLKIF-----------
Rv0785|M.tuberculosis_H37Rv AFDRPEDYWPEQWAHAYVDFAAGEKRS--WLRARGLKIFPLVGWAERGGY
MSMEG_1129|M.smegmatis_MC2_155 ADSELANFLIQFAANCRRASWKRAMRANVPLNEESLEAFDVLFANGVD--
Mvan_4780|M.vanbaalenii_PYR-1 ADTALARFLLRFAANCRPSAWERAVRANAILNDEAIETFDVLVSNGVD--
TH_2138|M.thermoresistible__bu RDLRQWAFLTRFAANCRRSSWTRALLANKPLNDEAIEAYDVLTANGVD--
Mflv_0955|M.gilvum_PYR-GCK ADPRLIGFLLRFARNSTASRWQKAMKALIPLNRDALAAFDRMEVQSSE--
MMAR_4421|M.marinum_M DIYRLTGGLFIGPPDCATVAGSLRASREWDLPHEVLDAPQIAARFPNFT-
.. * :
Mb0807|M.bovis_AF2122/97 --------------RWWAGPSVV---------------------------
Rv0785|M.tuberculosis_H37Rv DAQGHGNSVPRFHITWGTGPALVDIFVRQLRDRPTVRFAHRHQVDKLIVE
MSMEG_1129|M.smegmatis_MC2_155 --------------APLTDAPITALFSTTAEAERMMRDLRALEDAGQTVS
Mvan_4780|M.vanbaalenii_PYR-1 --------------APVTDTSLAVAFRDAGHAELFLTELNHLRSTGQQLH
TH_2138|M.thermoresistible__bu --------------APVTDAPITAVFRDPREAGRLRDELRRVAETGRDVE
Mflv_0955|M.gilvum_PYR-GCK --------------QSSPAEPFIAAYRTAADREVLLEEFAQIRAAGQSVN
MMAR_4421|M.marinum_M --------------PQPTDIALYEAKAGLARPELTVRAHLELAKRSGATL
. ..
Mb0807|M.bovis_AF2122/97 ---VTTRRGTAT--------------------------------------
Rv0785|M.tuberculosis_H37Rv GNAVTGVRGTVLEPSDEPRGAPSSRKSVGKFEFRASAVIVASGGIGGNHE
MSMEG_1129|M.smegmatis_MC2_155 VSGLSGQQLREQVPLTSPAVAAALNVNGQRYVDPGRFVQALRRAVEERGA
Mvan_4780|M.vanbaalenii_PYR-1 VETLTGAALHEQVPLASSNVAAVVNVSGQRFVDPGRFTHALGFAVAERGA
TH_2138|M.thermoresistible__bu VTELSGADLRERVPLASAEITVGLEIHGQRYVDPARFVQALADSVVDRGA
Mflv_0955|M.gilvum_PYR-GCK FEVLDGATARAQEPALSPEVDAAIAIHDERFVNPSAYVDALAAQVLARGG
MMAR_4421|M.marinum_M QFEEPVLNWTTTASGVRVTTGRDTYTAEQLVVCPGAWAPELLSQLG----
Mb0807|M.bovis_AF2122/97 --------------------------------------------------
Rv0785|M.tuberculosis_H37Rv LVRKNWPRRMGRIPKQLLSGVPAHVDGRMIGIAQKAGAAVINPDRMWHYT
MSMEG_1129|M.smegmatis_MC2_155 TMRT------MEVSDVLSSGNGVQVYPRIGKWLTADVAVVATGAWLPRLA
Mvan_4780|M.vanbaalenii_PYR-1 TMLS------GEVCRVSGSRDGALLELRDRELLRGDAVVLATGAWLPALT
TH_2138|M.thermoresistible__bu TIHR------MDITGVDSGPGGVTVHSAGGQELSAGAVVIATGAWLHQLA
Mflv_0955|M.gilvum_PYR-GCK RIEAG-----VDVDSVSDTGDGVRVAG-----QRYDAAVVATGARLNKLL
MMAR_4421|M.marinum_M ----------------------IPITVQRQVMYWLDPVGGTAGFRDHPIF
Mb0807|M.bovis_AF2122/97 -------------------------------RCPVSTSPG----------
Rv0785|M.tuberculosis_H37Rv EGITNYDPIWPRHGIRIIPGPSSLWLDAAGKRLPVPLFPGFDTLGTLEYI
MSMEG_1129|M.smegmatis_MC2_155 GSR---------------------------ITVPVQAARRYSFTVPVDRP
Mvan_4780|M.vanbaalenii_PYR-1 GRR---------------------------IRVGLQAGRGYSFTVPVDRA
TH_2138|M.thermoresistible__bu QRW---------------------------VRVPVQAGRGYSFTVPVDRP
Mflv_0955|M.gilvum_PYR-GCK APFG--------------------------VRRTVQAGRGYSFTVKVDHL
MMAR_4421|M.marinum_M IAE----------------------------NDSGAQIYGFPAIDGPRGG
Mb0807|M.bovis_AF2122/97 -----------------------------------VLGRLWST-------
Rv0785|M.tuberculosis_H37Rv TKSGHDYTWFVLNAKIIEKEFALSGQEQNPDLTGRRLGQLLRSRAHAGPP
MSMEG_1129|M.smegmatis_MC2_155 IPTPIYLPEAGIACTPHKGALRVTGATELRDPYEPAMPSRVGAMVAAAEP
Mvan_4780|M.vanbaalenii_PYR-1 LPGPVYLPEARVACTPYRGGLRVAGTMEFRRPSEPLAQRRIDAIIASATP
TH_2138|M.thermoresistible__bu VPAPVYLPEVRVACTPCAAGLRVAGTMEFRDPDAPLISKRVDAIVAAARP
Mflv_0955|M.gilvum_PYR-GCK PRGPVYFPTQRVACTPVGDRLRIAGMMEFRAVDAPLDPRRIEVLKNAAGE
MMAR_4421|M.marinum_M VKVAFFRKGIACTPDTIDRVVGPQEIHEMITRVGELLPALAGTCLQAATC
Mb0807|M.bovis_AF2122/97 ------------------------------------YSCVSCVIAPR---
Rv0785|M.tuberculosis_H37Rv GPVQAFIDRGVDCVHANSLRELVAAMNELPDVVPLDYETVAAAVTARDRE
MSMEG_1129|M.smegmatis_MC2_155 LLEGVRWAERSD--------IWVGPGALTPDGRPLIG-EMSRGVYLAGGH
Mvan_4780|M.vanbaalenii_PYR-1 LLDGVRWTERTD--------AWVGPRPVTDDGKPLIG-QLASAMYVAGGH
TH_2138|M.thermoresistible__bu LLDGVRWDERGP--------SWVGPRPVTPDGRPLIG-AVAEDVYVAAGH
Mflv_0955|M.gilvum_PYR-GCK LLTGAHLDTRED--------EWVGARPCTADGLPLIGRTRSSRVFAAGGH
MMAR_4421|M.marinum_M MYSN-----------------------TPDQHFVIARHPYCPAVTVACGF
. :
Mb0807|M.bovis_AF2122/97 -----------CALRTATRSTN----------------------------
Rv0785|M.tuberculosis_H37Rv VVNKYSKDGQITAIRAARRYRGDRFGRVVAPHRLTDPKAGPLIAVKLHIL
MSMEG_1129|M.smegmatis_MC2_155 GMWGLAHGPVTGRLLAEYITTGKQPEALRPFDPLRRTG-ADP--------
Mvan_4780|M.vanbaalenii_PYR-1 GMWGLAHGPATGRLLAEQIVTGKQPEAVRPFDPLRGRGRATPTEVLTLPL
TH_2138|M.thermoresistible__bu GMWGLTHGPVTGRLLAEQITTGKQPDVLDEFDPLR---------------
Mflv_0955|M.gilvum_PYR-GCK GMWGITLGPVTGRLLAEQIVTGRTPDALRAVDPLR---------------
MMAR_4421|M.marinum_M SGHGFKFVPVVGEILADLVTEGATSQPISLFDPQRLVTV-----------
: : .
Mb0807|M.bovis_AF2122/97 --------------------------------------------------
Rv0785|M.tuberculosis_H37Rv TRKTLGGIETDLDARVLKADGTPLAGLYAAGEVAGFGGGGVHGYRALEGT
MSMEG_1129|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4780|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_2138|M.thermoresistible__bu --------------------------------------------------
Mflv_0955|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_4421|M.marinum_M --------------------------------------------------
Mb0807|M.bovis_AF2122/97 ---------------------
Rv0785|M.tuberculosis_H37Rv FLGGCIFSGRAAGRGAAEDIR
MSMEG_1129|M.smegmatis_MC2_155 ---------------------
Mvan_4780|M.vanbaalenii_PYR-1 ---------------------
TH_2138|M.thermoresistible__bu ---------------------
Mflv_0955|M.gilvum_PYR-GCK ---------------------
MMAR_4421|M.marinum_M ---------------------