For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VALTCTDMSDAVAGSDAEGLTADAIVVGAGLAGLVAACELADRGLRVLILDQENRANVGGQAFWSFGGLF LVNSPEQRRLGIRDSHELALQDWLGTAAFDRPEDYWPEQWAHAYVDFAAGEKRSWLRARGLKIFRWWAGP SVVVTTRRGTATRCPVSTSPGVLGRLWSTYSCVSCVIAPRCALRTATRSTN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0807 | - | - | 100% (191) | hypothetical protein Mb0807 |
| M. bovis AF2122 / 97 | Mb3567 | - | 1e-07 | 40.30% (67) | 3-ketosteroid-delta-1-dehydrogenase |
| M. bovis AF2122 / 97 | Mb3195 | aofH | 1e-04 | 52.38% (42) | flavin-containing monoamine oxidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1621 | - | 1e-55 | 86.09% (115) | putative FAD-binding dehydrogenase |
| M. tuberculosis H37Rv | Rv0785 | - | 2e-75 | 100.00% (134) | putative FAD-binding dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0695 | - | 2e-55 | 72.86% (140) | putative FAD-binding dehydrogenase |
| M. marinum M | MMAR_4632 | - | 2e-40 | 67.83% (115) | hypothetical protein MMAR_4632 |
| M. avium 104 | MAV_0732 | - | 1e-59 | 85.37% (123) | putative FAD-binding dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5835 | - | 2e-54 | 84.96% (113) | putative FAD-binding dehydrogenase |
| M. thermoresistible (build 8) | TH_0564 | - | 1e-51 | 81.42% (113) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_4098 | - | 4e-06 | 37.31% (67) | 3-ketosteroid-delta-1-dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_5132 | - | 1e-55 | 86.73% (113) | putative FAD-binding dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1621|M.gilvum_PYR-GCK -------------------MTADVIVVGAGLAGLVAACELAERGRSVLIV
Mvan_5132|M.vanbaalenii_PYR-1 ---------MADVSSAPHVRAADVIVVGAGLAGLVAACELADRGRSVLIV
TH_0564|M.thermoresistible__bu ------------------MADADVIVVGAGLAGLVAACELVDRGRRVLIV
MAB_0695|M.abscessus_ATCC_1997 ----------------MGDTSTDVIVVGAGLAGLVAACELVDRGKRVVIV
MSMEG_5835|M.smegmatis_MC2_155 ----------------MAD--ADVIVVGAGLAGLVAACELVERGHSVIIV
Rv0785|M.tuberculosis_H37Rv MALTCTDMSDAVAGSDAEGLTADAIVVGAGLAGLVAACELADRGLRVLIL
MAV_0732|M.avium_104 -------MSD----SSVAAFGADAIVVGAGLAGLVAACELVDRGLRVLVL
MMAR_4632|M.marinum_M -------------------MDADVIVVGAGLAGLVATHELTRRGKKVAVV
Mb0807|M.bovis_AF2122/97 MALTCTDMSDAVAGSDAEGLTADAIVVGAGLAGLVAACELADRGLRVLIL
MUL_4098|M.ulcerans_Agy99 ----------------MTSQDYDVVVVGSGGAGMVAALAAAHKGLSTVVI
*.:***:* **:**: . :* . ::
Mflv_1621|M.gilvum_PYR-GCK DQENSANVGGQAYWSFGGLFFVDSPEQRRLGIRDSHELALQDWLGTAGFD
Mvan_5132|M.vanbaalenii_PYR-1 DQENSANIGGQAYWSFGGLFFVDSPEQRRVGIRDSHELALQDWLGTAGFD
TH_0564|M.thermoresistible__bu DQENAANLGGQAYWSFGGLFFVDSPEQRRLGIRDSYELAWQDWLGTAGFD
MAB_0695|M.abscessus_ATCC_1997 EQENAANLGGQAYWSFGGLFFVNSPEQRRLGIKDSHELALQDWLGTAGFD
MSMEG_5835|M.smegmatis_MC2_155 DQENAANIGGQAFWSFGGLFFVNSPEQRRLGIRDSQELALQDWLGTAGFD
Rv0785|M.tuberculosis_H37Rv DQENRANVGGQAFWSFGGLFLVNSPEQRRLGIRDSHELALQDWLGTAAFD
MAV_0732|M.avium_104 DQENSANLGGQAFWSFGGLFFVDSPEQRRLGIRDSHELALQDWLGTAAFD
MMAR_4632|M.marinum_M DQENEKNLGGQAFWSFGGLFLVDSPEQRHLGIKDSLELAWNDWSGSAAFD
Mb0807|M.bovis_AF2122/97 DQENRANVGGQAFWSFGGLFLVNSPEQRRLGIRDSHELALQDWLGTAAFD
MUL_4098|M.ulcerans_Agy99 EK--AAHYGGSTARSGGGVWIPNNQILKRARVSDTTEAARTYLHGIIGDS
:: : **.: * **::: :. :: : *: * * * . .
Mflv_1621|M.gilvum_PYR-GCK RA--EDHWPRQWAHAYVDFAAGEKRSWLRDRGLQIFPLVGWAERGGYDAN
Mvan_5132|M.vanbaalenii_PYR-1 RP--EDHWPRQWAHAYVDFAAGEKRSWLRDRGLQIFPLVGWAERGGYGAN
TH_0564|M.thermoresistible__bu RP--EDYWPRKWAEAYVNFATYEKRTWLRARGLQTFPVVGWAERGGYDAR
MAB_0695|M.abscessus_ATCC_1997 RP--EDHWPRQWAHAYVDFAAGEKRSWLRARGLQTFPVVAWAERGGKDAL
MSMEG_5835|M.smegmatis_MC2_155 RP--EDHWPREWAHAYVDFAAGEKRSWLRARGLQTFPLVGWAERGGYDAL
Rv0785|M.tuberculosis_H37Rv RP--EDYWPEQWAHAYVDFAAGEKRSWLRARGLKIFPLVGWAERGGYDAQ
MAV_0732|M.avium_104 RP--EDFWPRQWAHAYVDFAAGEKRSWLRARGLKLFPLVGWAERGGYDAQ
MMAR_4632|M.marinum_M RPDDEDFWATKWARAYVEFAAGEKRSYLTDLGIRFMPTVGWAERGDLRAE
Mb0807|M.bovis_AF2122/97 RP--EDYWPEQWAHAYVDFAAGEKRSWLRARGLKIF--------------
MUL_4098|M.ulcerans_Agy99 SVS---GVEPERIDTYLERGPEMLSFVLEHTPLKMCWVPGYSDYYSEAPG
: :*:: .. * ::
Mflv_1621|M.gilvum_PYR-GCK GHGNSVPRFHITWGTGPALVDIFARRLIGNP-----------RVRFAHRH
Mvan_5132|M.vanbaalenii_PYR-1 GHGNSVPRFHITWGTGPALVDIFARRLIGNP-----------RVRFAHRH
TH_0564|M.thermoresistible__bu GHGNSVPRFHITWGTGPAIVDIFARRLHAAAERS--------QVRFAFRH
MAB_0695|M.abscessus_ATCC_1997 GPGNSVPRFHITWGTGPGLVEIFARRVLAAVDRG--------QVRIAYRH
MSMEG_5835|M.smegmatis_MC2_155 GHGNSVPRFHITWGTGPALVEIFARRIRDSVR-----------VRFAHRH
Rv0785|M.tuberculosis_H37Rv GHGNSVPRFHITWGTGPALVDIFVRQLRDRP-----------TVRFAHRH
MAV_0732|M.avium_104 GHGNSVPRFHITWGTGPALVEIFARRLRDRS-----------TVRFAHRH
MMAR_4632|M.marinum_M GHGNSVPRFHIAWGTGTGVVEPFVDSALQSAKDK--------LVTFYHRH
Mb0807|M.bovis_AF2122/97 -----------RWWAGPSVVVTTR--------------------------
MUL_4098|M.ulcerans_Agy99 GRSGGRSIEPKPFDARKLGADMAELEPAYGKIPLNVVVMQQDYVRLNQLK
: : .
Mflv_1621|M.gilvum_PYR-GCK RVDELIVDDGSVIGVRGAVLEPSDAVRGAPSSRNVVGDFEFRGQAVIVAS
Mvan_5132|M.vanbaalenii_PYR-1 RVDELIVDDGAVVGVRGAVLEPSSAVRGAESSRNVVGDFEFRAQAVIVAS
TH_0564|M.thermoresistible__bu RVDELIVEDGVVVGVRGSVLEPSQAPRGFASSRKVVGDFEFRDAAVIVAS
MAB_0695|M.abscessus_ATCC_1997 QVDELVVDQGAVVGVRGTVLEPSTAARGIASSRIKLGEFEFRAQAVIVTS
MSMEG_5835|M.smegmatis_MC2_155 RVDELIVNAGLVAGVRGSILEPSNAPRGVASSRKVVGDFEFRASAVIVAS
Rv0785|M.tuberculosis_H37Rv QVDKLIVEGNAVTGVRGTVLEPSDEPRGAPSSRKSVGKFEFRASAVIVAS
MAV_0732|M.avium_104 RVDELIVEGGAVTGVRGSVLEPSAAPRGVASSRNTIAQFEFRADAVIVTS
MMAR_4632|M.marinum_M RVDELVITDGVATGIKGTVLAPDDAERATSSNRDEVGEFELSAQAVIITT
Mb0807|M.bovis_AF2122/97 --------------------------RGTATR------------CPVSTS
MUL_4098|M.ulcerans_Agy99 RHPRGVLRSMKVGARTMWAKATGKNLVGMGRALIGPLRIGLQRKGVPVQL
.
Mflv_1621|M.gilvum_PYR-GCK GGIGGNHELVRKYWPERMGRVPEQLLSGVPAHVDGRMLEISATAGASVIN
Mvan_5132|M.vanbaalenii_PYR-1 GGIGGNHELVRKCWPKRMGRVPEQLLSGVPAHVDGRMLEISATAGASVIN
TH_0564|M.thermoresistible__bu GGIGGNHDLVRQNWPPRMGRVPEQMLSGVPAYVDGRMMEIAEEAGANVIN
MAB_0695|M.abscessus_ATCC_1997 GGIGGNHDLVRENWPERLGRVPSQLLTGVPAHVDGRMLGISVAAGAHLIN
MSMEG_5835|M.smegmatis_MC2_155 GGIGGNLELVRKNWPARLGRVPDQLISGVPAHVDGRMIGIAESAGAHVIN
Rv0785|M.tuberculosis_H37Rv GGIGGNHELVRKNWPRRMGRIPKQLLSGVPAHVDGRMIGIAQKAGAAVIN
MAV_0732|M.avium_104 GGIGGNHELVRKNWPKRMGRVPEQLLSGVPAHVDGRMIEITQRAGARVIN
MMAR_4632|M.marinum_M GGIGGNHDMVRRYWPDRMGTPPASMITGVPAYVDGRMLDIANDSGVRLVN
Mb0807|M.bovis_AF2122/97 PGVLG---------------------------------------------
MUL_4098|M.ulcerans_Agy99 NTALTDLYLEDGVVRGIYVRSTDAHESEEPQLIRARKGVILACGGFDHNE
Mflv_1621|M.gilvum_PYR-GCK SDRMWHYTEGITNYDPIWPRHG-----IRILPGPSSLWLDATGKRLPVPL
Mvan_5132|M.vanbaalenii_PYR-1 SDRMWHYTEGITNYDPIWPRHG-----IRILPGPSSLWLDAAGKRLPVPL
TH_0564|M.thermoresistible__bu SDRMWHYTEGITNYDPIWPLHG-----IRILPGPSSLWLDAHGKRLPAPL
MAB_0695|M.abscessus_ATCC_1997 RDRMWHYTEGITNHNPIWPGHG-----IRILPGPSSLWLDANGSRIPAPL
MSMEG_5835|M.smegmatis_MC2_155 NDRMWHYTEGITNYDPVWPNHG-----IRILPGPSSLWLDANGDRLPVPL
Rv0785|M.tuberculosis_H37Rv PDRMWHYTEGITNYDPIWPRHG-----IRIIPGPSSLWLDAAGKRLPVPL
MAV_0732|M.avium_104 PDRMWHYTEGITNYEPIWPRHG-----IRIIPGPSSLWLDANGKRLPVPL
MMAR_4632|M.marinum_M RDRMWHYTEGVNNWDPIWPKHA-----IRIIPGPSSMWFDALGRRLPAPY
Mb0807|M.bovis_AF2122/97 --RLWSTYSCVS--CVIAPRCA-----LRTATRSTN--------------
MUL_4098|M.ulcerans_Agy99 QMRVKYQRAPITTDWTVGAKANTGDGIVAAEKLGAALDLMEDAWWGPTVP
*: :. : . : :
Mflv_1621|M.gilvum_PYR-GCK YPGFDTLGTLEHIAQT----GQDYTWFVLNSRIIDKEFGLSGQEQNPDLT
Mvan_5132|M.vanbaalenii_PYR-1 YPGFDTLGTLEYIAQT----GQDYTWFVLNSRIIAKEFGLSGQEQNPDLT
TH_0564|M.thermoresistible__bu YPGFDTLGTLEYITQT----GQDYTWFILNARIIAKEFALSGQEQNPDLT
MAB_0695|M.abscessus_ATCC_1997 FPGFDTLGTLEHICRS----GQDYSWFILNARIIAKEFALSGQEQNPDLT
MSMEG_5835|M.smegmatis_MC2_155 YPGYDTLGTLEHICRS----GQDYTWFILNARIIAKEFALSGQEQNPDLT
Rv0785|M.tuberculosis_H37Rv FPGFDTLGTLEYITKS----GHDYTWFVLNAKIIEKEFALSGQEQNPDLT
MAV_0732|M.avium_104 YPGFDTLGTLEYITKS----GFDYTWFVLNAKIIEKEFALSGQEQNPDLT
MMAR_4632|M.marinum_M LPGYDTLGTLRHLRTTPEIAKYDHSWFILNQKIIKKEFALSGSEQNPDIT
Mb0807|M.bovis_AF2122/97 --------------------------------------------------
MUL_4098|M.ulcerans_Agy99 LVGRPWFALSERNSPGSIIVNMSGQRFMNESMPYVEACHHMYGGQYGQGP
Mflv_1621|M.gilvum_PYR-GCK GRSIRAVLE--RSRKG-PAPVHAFVDKGVDFVTATSLRELVTRMNAIPGV
Mvan_5132|M.vanbaalenii_PYR-1 DRSIRAVLE--RGRKG-PAPVHAFVDKGVDFVTATSLRELVTKMNAVPDV
TH_0564|M.thermoresistible__bu GRSVRDVLA--RIRPGAPEPVQAFVDRGADFVSANSLQGLVAAMNELPDV
MAB_0695|M.abscessus_ATCC_1997 GKDVRGVLR--RGKAGAPAPVQAFVDNGVDFVTATNLPDLVAKMNALPDV
MSMEG_5835|M.smegmatis_MC2_155 SRNVRDLLS--RVKPGAPAPVQAFVDHGVDFVSATSLRDLVAGMNDLPDV
Rv0785|M.tuberculosis_H37Rv GRRLGQLLRS-RAHAGPPGPVQAFIDRGVDCVHANSLRELVAAMNELPDV
MAV_0732|M.avium_104 GQSVRELLRN-RARSGPPGPVQAFVDRGVDFVSANSLRELVTAMNKLPDV
MMAR_4632|M.marinum_M GKSRKAVLQERFLNKDATGPVEAFKRHGADFVVANSLEELVEKMNGLTDE
Mb0807|M.bovis_AF2122/97 --------------------------------------------------
MUL_4098|M.ulcerans_Agy99 GPGENIPAWLVFDQRYRDRYIFAGLQPGQRIPRKWLDSGVIVMADTLEEL
Mflv_1621|M.gilvum_PYR-GCK VPLEFGVVEAEVTARDRE--VTNRFTKDGQVTAIRAARAYLPDRISRVVA
Mvan_5132|M.vanbaalenii_PYR-1 VPLDFDVVEAEVTARDRE--VTNRFTKDGQITAIRAARAYLPDRISRVVA
TH_0564|M.thermoresistible__bu LPLDYATVAAEVAARDRE--VVNKFTKDTQVMAIRAARGYLGDRVSRVVA
MAB_0695|M.abscessus_ATCC_1997 SPLDYATIAQQVTARDRE--VANPFGKDPQIAAIRAARAYLADRVARVVA
MSMEG_5835|M.smegmatis_MC2_155 VPLDYAKVAAEVTARDRE--VANRFTKDGQITAIRAARNYLGDRFTRVVA
Rv0785|M.tuberculosis_H37Rv VPLDYETVAAAVTARDRE--VVNKYSKDGQITAIRAARRYRGDRFGRVVA
MAV_0732|M.avium_104 APLDYATVEAEVTARDRE--VANRFSKDGQITAIRAARGYLGDRLGRVVA
MMAR_4632|M.marinum_M PLLDPAAIRRQIEARDLQ--VANPFCKDVQVQGIRNARRALGDRLGRVAA
Mb0807|M.bovis_AF2122/97 --------------------------------------------------
MUL_4098|M.ulcerans_Agy99 AAKAGLPVDELTSTVSRFNGFARSGVDEDYHRGESAYDRYYGDPTNKPNP
Mflv_1621|M.gilvum_PYR-GCK PHRLTDPKAGPLIAVKLHILTRKSLGGLQTDLDSRVLRADGTVLPGLYAA
Mvan_5132|M.vanbaalenii_PYR-1 PHRLTDPKAGPLIAVKLHILTRKSLGGLQTDLDSRVLHDDGTVLPGLYAA
TH_0564|M.thermoresistible__bu PHRLTDSKAGPLIAVKLHILTRKTLGGLETDLDSRVLRGDGEVFDGLYAA
MAB_0695|M.abscessus_ATCC_1997 PHRLTDPKAGPLIAVKLHILTRKTLGGLETDLDSRVLRADGSCFEGLYAA
MSMEG_5835|M.smegmatis_MC2_155 PHRLTDPKAGPLIAVKLHILTRKTLGGLETDLDSRVLKEDGTTFGGLYAA
Rv0785|M.tuberculosis_H37Rv PHRLTDPKAGPLIAVKLHILTRKTLGGIETDLDARVLKADGTPLAGLYAA
MAV_0732|M.avium_104 PHRLTDPKAGPLIAVKLHILTRKTLGGIETDLASRVLGADGTPLTGLYAA
MMAR_4632|M.marinum_M PHRILDPKAGPLIATKLHILTRKTLGGIQTDLSSRAIGSNGEPIAGLYAA
Mb0807|M.bovis_AF2122/97 --------------------------------------------------
MUL_4098|M.ulcerans_Agy99 --NLGEINHAPYYAAKMVPGDLGTKGGIRTDVNGRALRDDGSIIDGLYAA
Mflv_1621|M.gilvum_PYR-GCK GEAAGFGGGGVHGYRSLEGTFLGGCVFSGRAAGRHAAVAVG
Mvan_5132|M.vanbaalenii_PYR-1 GEAAGFGGGGVHGYRSLEGTFLGGCVFSGRAAGRHAASAVG
TH_0564|M.thermoresistible__bu GEAAGFGGGGVHGYRSLEGTFLGGCIFSGRAAGRAAARDTA
MAB_0695|M.abscessus_ATCC_1997 GEVAGFGGGGVHGYRALEGTFLGGCIFSGRAAGRGAAEDIG
MSMEG_5835|M.smegmatis_MC2_155 GEAAGFGGGGVHGYRSLEGTFLGGCIFSGRAAGRGAAADIA
Rv0785|M.tuberculosis_H37Rv GEVAGFGGGGVHGYRALEGTFLGGCIFSGRAAGRGAAEDIR
MAV_0732|M.avium_104 GEAAGFGGGGVHGYRALEGTFLGGCIFSGRAAGRGVADDIT
MMAR_4632|M.marinum_M GEVAGFGGGGVHGYNALEGTFLGGCIFSGRAAGRAAADAV-
Mb0807|M.bovis_AF2122/97 -----------------------------------------
MUL_4098|M.ulcerans_Agy99 GNVSAPVMG--HTYPGPGGTIGPAMTFGYLAALHIAGDR--