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M. smegmatis MC2 155 MSMEG_0849 (-)

annotation: oxygenase
coordinates: 933768 - 934085
length: 105

VLVVGAGPTGPMPACEPTLGGVRAVLLDERTDAPGITRAFAVHARTLQLLDARGLTADLPARGLPVPEVA
PPGAVVSKLSELPTEFGMILMLPQSGTRRPAPRLH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0849--100% (105)oxygenase
M. smegmatis MC2 155MSMEG_1699-2e-0935.64% (101) pentachlorophenol 4-monooxygenase
M. smegmatis MC2 155MSMEG_2252-4e-0832.69% (104) flavin-type hydroxylase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_5009-2e-0642.19% (64) monooxygenase, FAD-binding
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0857-5e-0833.00% (100) hypothetical protein MAB_0857
M. marinum MMMAR_4271-2e-0937.00% (100) hypothetical protein MMAR_4271
M. avium 104MAV_2736-2e-1042.00% (100) hypothetical protein MAV_2736
M. thermoresistible (build 8)TH_1880-1e-1136.36% (99) flavin-type hydroxylase
M. ulcerans Agy99MUL_3663-2e-0532.65% (98) hypothetical protein MUL_3663
M. vanbaalenii PYR-1Mvan_2422-8e-0737.62% (101) hypothetical protein Mvan_2422

CLUSTAL 2.0.9 multiple sequence alignment


MAV_2736|M.avium_104                MRGVRFSE--RSVRG----------------------HAVLVAGAGPTGL
Mvan_2422|M.vanbaalenii_PYR-1       MTTTRHKDTHKDTREDTREDTRDDSRDDGGDPNGDTDHAVVVGGGGPTGM
MMAR_4271|M.marinum_M               MAD----------------------------------HAVVVVGAGPTGL
MAB_0857|M.abscessus_ATCC_1997      MAE----------------------------------HAVVVAGAGPTGL
TH_1880|M.thermoresistible__bu      ------------------------------------VYDVIVVGGGPTGM
Mflv_5009|M.gilvum_PYR-GCK          MPGAHR-------------------------------SDVVVVGAGPTGL
MSMEG_0849|M.smegmatis_MC2_155      ---------------------------------------MLVVGAGPTGP
MUL_3663|M.ulcerans_Agy99           MPQPSE------------------------------TTSVLVAGGGPAGM
                                                                           ::* *.**:* 

MAV_2736|M.avium_104                MLAGELGLAGVDVALVERRADQQLIGSRAGGLHARTLEILDQRGIVDRFL
Mvan_2422|M.vanbaalenii_PYR-1       MTAAELALAGVDVAVVERRTTPEITGSRAGGLLSRTLEILDQRGVVDRFL
MMAR_4271|M.marinum_M               MLAGELALAGVDVAVVERRVSQDLVGSRAGGLHSRTIEVLDQRGIADRFL
MAB_0857|M.abscessus_ATCC_1997      MLAGELALAGIDVALLERRGSHEEVGSRAAGLHSRTIEVFDQRGIAERFL
TH_1880|M.thermoresistible__bu      MLAGELRLHGVRVLVVEKN-SEPPAHVRSLGLHVRSIEMLDQRGLLDRFL
Mflv_5009|M.gilvum_PYR-GCK          TLACCLRLHGVSVRVLDAAAGPATT-SRANFLHARGSEVLDRMGALGTLP
MSMEG_0849|M.smegmatis_MC2_155      MPACEPTLGGVRAVLLDER-TDAPGITRAFAVHARTLQLLDARGLTADLP
MUL_3663|M.ulcerans_Agy99           VLGLLLARAGVDVTVMEKH-ADFLRDSRGDTVHASTLRLLDELGLGSQFA
                                      .      *: . :::          *.  :     .::*  *    : 

MAV_2736|M.avium_104                AEG-QVAQVAG-FAQIRLDISDFP----TRHPYGLALWQNHIERILADWV
Mvan_2422|M.vanbaalenii_PYR-1       SAG-ETMQVHG-FAQVRLDVSDLP----TRHPYGLALWQKHIERILAEWV
MMAR_4271|M.marinum_M               AQG-TATQVAR-FAAIPLDISDFP----TRHNYGLALWQNRIERILAEWV
MAB_0857|M.abscessus_ATCC_1997      AQG-RTGQVTH-FSGIFMSIEDFP----TRHPYALGLLQHYTEKTLAAWI
TH_1880|M.thermoresistible__bu      AHG-QRHPVGGFFAAIAKPPAELD----TAHGYVLGIRQPVTDRLLAEWA
Mflv_5009|M.gilvum_PYR-GCK          QESLRALRITNYLGDRPLATLEFGDPGMRTAAPPMVVSQAKVEAALRARL
MSMEG_0849|M.smegmatis_MC2_155      ARGLPVPEVAP-PGAVVSKLSELP----TEFGMILMLPQSGTRRPAPRLH
MUL_3663|M.ulcerans_Agy99           QIPHRLIDTISMKVQGQPVDLDLKHLPGAHQHIALVPQWDFLELLAAAAE
                                                         ::           :               

MAV_2736|M.avium_104                GELGVPIYRGHRIATCTQDD---------TGVDVVASDGRTLRGQYLVGC
Mvan_2422|M.vanbaalenii_PYR-1       DELAVPVYRGREVVGVRQDG---------AGVDIELSDGRVLRAGYLVGC
MMAR_4271|M.marinum_M               AELRVRIYRGCEVTDITQDD---------NGVDLTLSDGPPLRADYVVGC
MAB_0857|M.abscessus_ATCC_1997      DELGVPIYYNAEAVGLGQDD---------VGVDVALADGSTLRGQYLVGC
TH_1880|M.thermoresistible__bu      AERGAVIRRGCAVVGLDQDA---------AGITVELADGSVQRARYLVGC
Mflv_5009|M.gilvum_PYR-GCK          ADLDVEPEWGRKVIDVREDA---------DGVVADLADGARVRGQWLVGC
MSMEG_0849|M.smegmatis_MC2_155      --------------------------------------------------
MUL_3663|M.ulcerans_Agy99           AEPTFRLLRSTEVTGVLWGDGPDPGRVVSATYRAQSGETKHMHADLTVAC
                                                                                      

MAV_2736|M.avium_104                DGGRSVIRKAAGIDFPGWEATTSYLLAEAEMDWRTGQPPQWG-IHHDSLG
Mvan_2422|M.vanbaalenii_PYR-1       DGGRSLIRKSAGIEFPGWEPTTSYLLAEVEIAPEDGREPEWG-IRRDALG
MMAR_4271|M.marinum_M               DGGRSLVRRAVGIDFPGWDPTTSSLIAEVEVAVGSESGPNLGEVRHDALG
MAB_0857|M.abscessus_ATCC_1997      DGGRSTIRKAAGIGFPGHDPSCSAMLVDAEIT---EQPLEFGLLRKPGQA
TH_1880|M.thermoresistible__bu      DGGRSTVRKLAGIGFPGEPARSETLLGEMSLSADPATVAAVVAEVRKTQL
Mflv_5009|M.gilvum_PYR-GCK          DGTTSVVRRQTGIEFPGVRLSERFLLADIHLDWAVDRAGTTGWIHPDGVV
MSMEG_0849|M.smegmatis_MC2_155      --------------------------------------------------
MUL_3663|M.ulcerans_Agy99           DGRGSTVRSALGMATRSFGAPMDVWWFR--LPRRPDDPTGLAGIFNSGHG
                                                                                      

MAV_2736|M.avium_104                VHALSETEP--AGGVRVLVTERQLRSA-AEPNLDDLRQALIAVYR-TDYG
Mvan_2422|M.vanbaalenii_PYR-1       VHALSRSD---DGPVRIMVTEQDLRRS-GVPDLAELREALVTVYG-TDFG
MMAR_4271|M.marinum_M               VHGFTRLPD--GGPLRVVVTERQLDAG-GEPSLGDLSAALTAVYG-TDYG
MAB_0857|M.abscessus_ATCC_1997      FLGILPFE---EGWCRLAFSTGLDRLG-VEPTLEEAKEALIAIAG-TDFG
TH_1880|M.thermoresistible__bu      RFGAMPLG---DGVYRVIVPAEGVAGDRAEPTLDEFRRRLKAFAG-TDFG
Mflv_5009|M.gilvum_PYR-GCK          GAMPMPSTDGRDDLWRLFVYDPSLDRKPTDSEILDRISELVPYRTGRRVK
MSMEG_0849|M.smegmatis_MC2_155      --------------------------------------------------
MUL_3663|M.ulcerans_Agy99           GIAIDRGDYYQIAYIIPKGSDAQLRAQ-GIEALHRALADLMPWLADRVDA
                                                                                      

MAV_2736|M.avium_104                IHSPRWISRFTDAARQAARYRDRRVLLAGDAAHIHHPVGGQGLNTGVQDA
Mvan_2422|M.vanbaalenii_PYR-1       IHSPTSISRFTDTARQAVAYRSGRILLVGDAAHVHHPVGGQGLNTGMQDA
MMAR_4271|M.marinum_M               IHSPTWISRFTDLTRQAATYRQGRVLIAGDAAHVHDPVGGQGLNTGVQDA
MAB_0857|M.abscessus_ATCC_1997      IHNPRWISRFSDMTRQADRYRDGRVFLAGDSAHIHFPFGGQGLNTGIQDA
TH_1880|M.thermoresistible__bu      AHTPRWLSRFGDATRLAERYRAGRVFLAGDAAHVHPPAGGQGLNLGIQDA
Mflv_5009|M.gilvum_PYR-GCK          IGDAEWLSMFTVHRRLADTYRRGRVLIAGDAAHVHAPFGGQGMLTGIGDA
MSMEG_0849|M.smegmatis_MC2_155      --------------------------------------------------
MUL_3663|M.ulcerans_Agy99           LKSFDDVKLLDVQLNRLRRWYCDGALCIGDAAHAMSPVGGVGINLALADA
                                                                                      

MAV_2736|M.avium_104                VNLGWKLALVVGG-ASPPALLDTYHAERHPVGERVLRNAIAQMALLRP-D
Mvan_2422|M.vanbaalenii_PYR-1       VNLGWKLAQVVQG-WSPDTLLDTYHDERQPVGARVLRNAVAQMALLRP-D
MMAR_4271|M.marinum_M               VNLGWKLAQVVNR-RSPESLLDTYHAERHPVAARVLRTTMAQVALRRL-D
MAB_0857|M.abscessus_ATCC_1997      VNLGWKLAAVIKG-HAPDALLDTYHLERHPVAERVLHNTMAQTPLSEA-G
TH_1880|M.thermoresistible__bu      FNLGWKLAAAVGG-WAPDGLLDTYHAERHPVAADVLNNTRAQMELMSP-E
Mflv_5009|M.gilvum_PYR-GCK          ENVGFKLALVVRG-LAADDLLDTYEAERRPLATQVLRGTSAITRVNVAGN
MSMEG_0849|M.smegmatis_MC2_155      --------------------------------------------------
MUL_3663|M.ulcerans_Agy99           VATARMLAPSLRVGRVSTGQLARVQARRWAPTAFLQGIQRAIHAAIVAVA
                                                                                      

MAV_2736|M.avium_104                ERTRALRDLVT-ELLGMDEPRKRFAAMISGLDVRYD-----LGPGHPLLG
Mvan_2422|M.vanbaalenii_PYR-1       DRTTVLHGVVS-DMLDMDEPRRRFAAMMSGLDIHYD-----LGDGHPLLG
MMAR_4271|M.marinum_M               YRKKALSDTIS-ELLMMDEPRKRFAAMMSGLDIRYH-----LGGGHPLLG
MAB_0857|M.abscessus_ATCC_1997      PRIDALRDIVA-DLLAMDEPRKRIAGMMSGLDIHYM-----LGDGHQLLG
TH_1880|M.thermoresistible__bu      PGPRAVRWLLA-ELMDFEEVNRYLTEKITAIGVRYHT----MGDGHGLLG
Mflv_5009|M.gilvum_PYR-GCK          PIVRFLRDRVAPRVFGLPAVQRWTTYTASQLWVSYRNGPLGGRGSKPRPG
MSMEG_0849|M.smegmatis_MC2_155      --------------------------------------------------
MUL_3663|M.ulcerans_Agy99           VTGGPPQPPPVVRLVSRSVPVRRIMGYLVAIG--------PLPEHAPKYP
                                                                                      

MAV_2736|M.avium_104                RRMPDLDLVTADGASRVFALLRNARPVLLNFAGAGRRSVAGWADRVRVVD
Mvan_2422|M.vanbaalenii_PYR-1       LRMPDLDLETAHGPTRVSALLRQARPVLLDLGAPDAVDLTGWEARVRMVR
MMAR_4271|M.marinum_M               RRMPDLDLTTADGPRRVFTHLHAARPVLLNLAEPGRFDIAGWRHRVLLID
MAB_0857|M.abscessus_ATCC_1997      RRMPDLDVVTADGAVRVYEHLHTARPVLFNFGARQILNVEGWEDRVHVVD
TH_1880|M.thermoresistible__bu      RRMRDIPLTGG----RLYARMHAGRGVLLDRTG--TLSVSGWADRVDHIV
Mflv_5009|M.gilvum_PYR-GCK          DRIDDAPCSRPDGTATRLHGELGGRWALLLPRGVPAVGAAAVRGPAGYLA
MSMEG_0849|M.smegmatis_MC2_155      --------------------------------------------------
MUL_3663|M.ulcerans_Agy99           RRAR----------------------------------------------
                                                                                      

MAV_2736|M.avium_104                AKCVADWELPVLGRVSAPPAVLIRPDGHVAWAGDP--NDPGLHDALTTWC
Mvan_2422|M.vanbaalenii_PYR-1       ANAATVWELPVIGEVPAPAAVLIRPDGHVAWVAGD--SAAAPAEAAARWF
MMAR_4271|M.marinum_M               AKYVGVWELPVLGAIAAPAAALIRPDGYVAWVGDDL-TDRGLFDALTAWF
MAB_0857|M.abscessus_ATCC_1997      AKYSGIWELPVLGEVSAPDAVLVRPDGYVAWVGEG--SADGLRGALTRWV
TH_1880|M.thermoresistible__bu      DP----------GAALDVPAVLLRPDGHVAWVGADHPGQQDLTARLSRWF
Mflv_5009|M.gilvum_PYR-GCK          DHVVT-------LHHDRDDVMLVRPDAHLAWRGAHD-DPTGLDRWLATAL
MSMEG_0849|M.smegmatis_MC2_155      --------------------------------------------------
MUL_3663|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

MAV_2736|M.avium_104                GPPAAGG--------
Mvan_2422|M.vanbaalenii_PYR-1       GAPTGRR--------
MMAR_4271|M.marinum_M               GRPAVPSPRLRASAP
MAB_0857|M.abscessus_ATCC_1997      GSPSRA---------
TH_1880|M.thermoresistible__bu      GAPA-----------
Mflv_5009|M.gilvum_PYR-GCK          HPGGTQ---------
MSMEG_0849|M.smegmatis_MC2_155      ---------------
MUL_3663|M.ulcerans_Agy99           ---------------