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MRDPEPAVSGAVGEVIRVRGLTFAYPKASTPAVRGMDFSVGRGEIFGFLGPSGAGKSTTQRILIGLLRGH GGEVAVWGKDPASWGSDYYERIGVSFELPNHYQKLTGLENLQFFASLYSAPTLDPMQLLEAVGLADHADT RAGKYSKGMQMRLTFARALLNDPELLFLDEPTSGMDPVNARSVKNMIMDLKARGRTVFLTTHDMATADEL CDRVAFVVDGSIVVSDRPAELKIARSQRLVTVEYRGNGGGLSAAEFSLDTLADDPAFHAVLREHQVETIH SREASLEDVFVEVTGRRLS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2026 | - | - | 100% (299) | antibiotic-transport ATP-binding protein ABC transporter |
| M. marinum M | MMAR_2263 | - | 2e-36 | 35.33% (317) | antibiotic ABC transporter ATP-binding protein |
| M. marinum M | MMAR_4220 | - | 1e-30 | 31.14% (289) | antibiotic ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2707c | - | 1e-134 | 79.79% (292) | antibiotic ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_2197 | - | 1e-36 | 34.25% (292) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2688c | - | 1e-133 | 79.45% (292) | antibiotic ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_00590 | - | 1e-35 | 35.83% (307) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_1858 | - | 1e-124 | 73.96% (288) | antibiotic ABC transporter ATP-binding protein |
| M. avium 104 | MAV_3321 | - | 6e-37 | 35.97% (303) | ABC transporter, ATP-binding subunit |
| M. smegmatis MC2 155 | MSMEG_1502 | - | 1e-130 | 76.21% (290) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_2745 | - | 3e-29 | 31.06% (293) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_1859 | - | 6e-36 | 35.53% (304) | antibiotic ABC transporter ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_0776 | - | 1e-125 | 76.14% (285) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1502|M.smegmatis_MC2_155 ----------MGSASEVIDVRDLTFTYPRAAEPAVRGMDFAVGNGEIFGF
Mvan_0776|M.vanbaalenii_PYR-1 ----------MNTES-VIDVRDLTYTYPKTAEPAVRGMDFAVGRGEIFGF
Mb2707c|M.bovis_AF2122/97 MTALNRAVASARVGTEVIRVRGLTFRYPKAAEPAVRGMEFTVGRGEIFGL
Rv2688c|M.tuberculosis_H37Rv MTALNRAVASARVGTEVIRVRGLTFRYPKAAEPAVRGMEFTVGRGEIFGL
MAB_1858|M.abscessus_ATCC_1997 -------------MTEVIQVRELTFTYPKTPEPAVRGMDFTVGEGEIFGF
MMAR_2026|M.marinum_M --MRDPEPAVSGAVGEVIRVRGLTFAYPKASTPAVRGMDFSVGRGEIFGF
MAV_3321|M.avium_104 -----------------MRLRGVSKHYG--STTAVRDLDLEVHAAEVLAL
MUL_1859|M.ulcerans_Agy99 ----------------MVRLRGVGKQYG--SVTAVSNLDLEVRAAEVMAL
MLBr_00590|M.leprae_Br4923 ---MSSACTVPETPEVVIRLRGVCKHYG--SILAVSNLDLDIHSAEVLAL
Mflv_2197|M.gilvum_PYR-GCK ----MPDTSP------VVEIRGLRKAFG--RTQALDGLDLAVAPGDVTGF
TH_2745|M.thermoresistible__bu ----MTTTSPRFDAEPAVEIHGLKKSFG--RTRAVDGLDLRVERGSVAGF
: :: : : *: .::: : ..: .:
MSMEG_1502|M.smegmatis_MC2_155 LGPSGAGKSTTQKLLIGLLRGHGGQALVWGRDPVDWGQDYYQRVGVSFEL
Mvan_0776|M.vanbaalenii_PYR-1 LGPSGAGKSTTQKLLIGLLRGHGGQALVWGRDPLDWGPRYYQRIGVSFEL
Mb2707c|M.bovis_AF2122/97 LGPSGAGKSTTQKLLIGLLRDHGGQATVWDKEPAEWGPDYYERIGVSFEL
Rv2688c|M.tuberculosis_H37Rv LGPSGAGKSTTQKLLIGLLRDHGGQATVWDKEPAEWGPDYYERIGVSFEL
MAB_1858|M.abscessus_ATCC_1997 LGPSGAGKSTTQKLLIGLLRGHGGRATVWGREPGAWGRNYYQRIGVSFEL
MMAR_2026|M.marinum_M LGPSGAGKSTTQRILIGLLRGHGGEVAVWGKDPASWGSDYYERIGVSFEL
MAV_3321|M.avium_104 LGPNGAGKTTTVEMCEGFVRPDAGTLEVLGLDPIADNARLRPRIGVMLQG
MUL_1859|M.ulcerans_Agy99 LGPNGAGKTTTVEMCEGFVRPDAGSIEVLGLDPIADNARLRPRIGVMLQG
MLBr_00590|M.leprae_Br4923 LGPNGAGKTTTVEMCEGFVRPDAGTIEVLGLDPITDNARLRARIGVMLQG
Mflv_2197|M.gilvum_PYR-GCK LGPNGAGKSTAIRVLLGLLRADGGDVRLLGADPWRDAVALHRRIAYVPGD
TH_2745|M.thermoresistible__bu LGPNGSGKSTTIRVLLGLLRADGGTARLLGGDPWHDAVELHRRLAYVPGD
***.*:**:*: .: *::* ..* : . :* *:.
MSMEG_1502|M.smegmatis_MC2_155 PNHYLRLTGLENLQFFASLYEKQTEDPMELLHAVGLADAAYTRVGEYSKG
Mvan_0776|M.vanbaalenii_PYR-1 PNHYLKLTGAENLQFFASLYDSAGPDPRSLLDDVGLTDAADTRVAKYSKG
Mb2707c|M.bovis_AF2122/97 PNHYQKLTGYENLRFFASLYAGATADPMQLLAAVGLADDAHTLVGKYSKG
Rv2688c|M.tuberculosis_H37Rv PNHYQKLTGYENLRFFASLYAGATADPMQLLAAVGLADDAHTLVGKYSKG
MAB_1858|M.abscessus_ATCC_1997 PNHYQKLTALENLRFFASLYAGPTRDPMELLDAVGLADDANTRVGAFSKG
MMAR_2026|M.marinum_M PNHYQKLTGLENLQFFASLYSAPTLDPMQLLEAVGLADHADTRAGKYSKG
MAV_3321|M.avium_104 GGGYPAARAGEMLNLVAAYAADP-LDPAWLLDTLGLTDAARTTYRRLSGG
MUL_1859|M.ulcerans_Agy99 GGGYPAARAGEMLDLVASYAADP-LDPRWLLDTLGLTDAARTTYRRLSGG
MLBr_00590|M.leprae_Br4923 GGGYPAARAGEMLNLVASYAADP-LDPEWLLETLGLTDVARTTYRRLSGG
Mflv_2197|M.gilvum_PYR-GCK VTLWPNLTGMQAIDFLTALRGDGVDTRRRDELIERFELDPHKKARTYSKG
TH_2745|M.thermoresistible__bu VTLWPNLTGGQAIDFLAGLR-DNFDTKRRDELIERFELDPDKKARTYSKG
: . : : :.:. : . . * *
MSMEG_1502|M.smegmatis_MC2_155 MQMRLTFARSLINKPELLFLDEPTSGLDPVNARRVKEIVLDLKSKGRTIF
Mvan_0776|M.vanbaalenii_PYR-1 MQMRLTFARSLVNDPELLFLDEPTSGLDPVNARRIKDIILDLKARGRTVF
Mb2707c|M.bovis_AF2122/97 MQMRLTFARSLINDPELLFLDEPTSGLDPVNARKIKDIIVDLKARGRTIF
Rv2688c|M.tuberculosis_H37Rv MQMRLPFARSLINDPELLFLDEPTSGLDPVNARKIKDIIVDLKARGRTIF
MAB_1858|M.abscessus_ATCC_1997 MQMRLTFVRALINDPELLFLDEPTSGLDPVNARKVKDMVLELKARGRTIF
MMAR_2026|M.marinum_M MQMRLTFARALLNDPELLFLDEPTSGMDPVNARSVKNMIMDLKARGRTVF
MAV_3321|M.avium_104 QQQRLALACALVGRPELVFLDEPTAGMDAHARLLVWELIDALRRDGVTVV
MUL_1859|M.ulcerans_Agy99 QQQRLALACALVGRPELVFLDEPTAGMDAHARLLVWELIDALRRDGVTVV
MLBr_00590|M.leprae_Br4923 QQQRLALACTLVGRPELVFLDEPTAGMDTHARLLVWELIDTLRRDGVTVV
Mflv_2197|M.gilvum_PYR-GCK NRQKVAIVAAFSTRSELFILDEPTSGLDPLMEKTFQECVREVAGRGAAVL
TH_2745|M.thermoresistible__bu NRQKVALVAAFSTNAEIYILDEPTSGLDPLMDKAFQMCVREAADNGAAVL
: ::.:. :: .*: :*****:*:*. . : * ::.
MSMEG_1502|M.smegmatis_MC2_155 LTTHDMSTADELCDRIAFVVDGSIVALDTPAELKIARSRRRVRVQYRV--
Mvan_0776|M.vanbaalenii_PYR-1 LTTHDMATADELCDRVAFVVDGRIVALDAPAELKIARSRRLVRVEYRS--
Mb2707c|M.bovis_AF2122/97 LTTHDMATADELCDRVAFVVDGRIVALDSPTELKIARSRRRVRVEYRG--
Rv2688c|M.tuberculosis_H37Rv LTTHDMATADELCDRVAFVVDGRIVALDSPTELKIARSRRRVRVEYRG--
MAB_1858|M.abscessus_ATCC_1997 ITTHAMSAADELCDRVAFVVDGRIVAMNSPAELKLEYGRRSVRVEYRG--
MMAR_2026|M.marinum_M LTTHDMATADELCDRVAFVVDGSIVVSDRPAELKIARSQRLVTVEYRG--
MAV_3321|M.avium_104 LTTHQLKEAEELADRLVIIDHGATVAAGTPAELMRSGAKDQLRFSAPPRL
MUL_1859|M.ulcerans_Agy99 LTTHQLKEAEELADRLVIIDHGVTVAEGTPSELMRSGAKDQLRFTAPPRL
MLBr_00590|M.leprae_Br4923 LTTHQLKEAEELADRLVIIDHGRMIAAGTPTELMHTGAKDQLRFSAPPRL
Mflv_2197|M.gilvum_PYR-GCK LSSHILAEVEKLCDSVTIVRSGRTVRSGTLAQMRQFMR-TTVTVRVRG--
TH_2745|M.thermoresistible__bu LSSHILAEVERLCDSVTIIRSGRTVRAGRLDELRHLMR-TTVKVRTRA--
:::* : .:.*.* :.:: * : . :: : .
MSMEG_1502|M.smegmatis_MC2_155 -------------ADGGLRTAEFGMDGLADDPEFHAVLR-----------
Mvan_0776|M.vanbaalenii_PYR-1 -------------AQGTLQTTEFPMDGLADDPEFRTVLR-----------
Mb2707c|M.bovis_AF2122/97 -------------DGGGLETAEFGMDGLADDPAFHSVLR-----------
Rv2688c|M.tuberculosis_H37Rv -------------DGGGLETAEFGMDGLADDPAFHSVLR-----------
MAB_1858|M.abscessus_ATCC_1997 -------------AAGELAGQDFPLDGLADNDAFHAVLR-----------
MMAR_2026|M.marinum_M -------------NGGGLSAAEFSLDTLADDPAFHAVLR-----------
MAV_3321|M.avium_104 DLSLLSAALPEDYKATELTPGEYLVEGPVDPQVLATVTAWCARI------
MUL_1859|M.ulcerans_Agy99 DLSLLVSALPEDYRVTEVTPGEYLVEGSVDPQVLAAVTAWCARI------
MLBr_00590|M.leprae_Br4923 DLSLLAFALPEDYKTTELTPGEYLVAGPIDPQVLATVTAWCAQI------
Mflv_2197|M.gilvum_PYR-GCK -------------DGRALVDAPYVHDLRTDDGALRFSVDRDHLDRAVLDL
TH_2745|M.thermoresistible__bu -------------PIDALRTAPYIHEFSTDDGLHTFSVDRTDLDRTMTEL
: : *
MSMEG_1502|M.smegmatis_MC2_155 -DHHVETIHSREASLDDVFVEVTGRQLA-
Mvan_0776|M.vanbaalenii_PYR-1 -DHHVETIHSREASLDEVFVDVTGRSLA-
Mb2707c|M.bovis_AF2122/97 -NHHVETIHSREASLDDVFVEVTGRQLT-
Rv2688c|M.tuberculosis_H37Rv -NHHVETIHSREASLDDVFVEVTGRQLT-
MAB_1858|M.abscessus_ATCC_1997 -GHHVETIHSEEASLDDVFVAVTGRRLA-
MMAR_2026|M.marinum_M -EHQVETIHSREASLEDVFVEVTGRRLS-
MAV_3321|M.avium_104 -DVLATDMRVEQRSLEDVFLDLTGRKLRQ
MUL_1859|M.ulcerans_Agy99 -DVLATDMRVEQRSLEDVFLDLTGRKLRS
MLBr_00590|M.leprae_Br4923 -NVLTTNMRVEQHSLEDVFLDLTGRKLR-
Mflv_2197|M.gilvum_PYR-GCK TALGIEDLAVAPASLEDMFLQEYQGANR-
TH_2745|M.thermoresistible__bu TTLGIEELTVTPASLEDLFLREYQEVPR-
: **:::*: