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KWIRALGVCCASVAAPLSAMTAPQAFAAPESCADVEVIFARGTGEAPGVGPTGQAFIDALRPRLGDRSVD VYPVNYPATDQWATGVDGVRDASTRIISMAETCPQTEMVLGGYSQGAAVAGFVTSAAVPDGVDPATVPKP LQPDIADHVAAVVLFGLPNERAMNFLGEPRVVIGPLYETKTRTYCATEDPVCSDGLNFAVHNPSSYDGDL TDQGAAFAADRINTGPVTATN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0194 | - | - | 100% (232) | serine esterase, cutinase family protein |
| M. smegmatis MC2 155 | MSMEG_1184 | - | 3e-60 | 53.36% (223) | serine esterase, cutinase family protein |
| M. smegmatis MC2 155 | MSMEG_4465 | - | 3e-49 | 48.65% (222) | cutinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1788 | cut1 | 3e-59 | 52.34% (214) | cutinase Cut1 |
| M. gilvum PYR-GCK | Mflv_4439 | - | 2e-55 | 50.93% (214) | cutinase |
| M. tuberculosis H37Rv | Rv1758 | cut1 | 2e-47 | 53.29% (167) | cutinase Cut1 |
| M. leprae Br4923 | MLBr_00099 | - | 0.0001 | 26.98% (126) | hypothetical protein MLBr_00099 |
| M. abscessus ATCC 19977 | MAB_3272c | - | 6e-44 | 48.69% (191) | cutinase Cut1 |
| M. marinum M | MMAR_2419 | cut1 | 4e-85 | 67.12% (222) | cutinase Cut1 |
| M. avium 104 | MAV_2169 | - | 2e-81 | 63.80% (221) | serine esterase cutinase |
| M. thermoresistible (build 8) | TH_0238 | - | 2e-83 | 69.52% (210) | serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_1597 | cut1 | 1e-83 | 69.38% (209) | cutinase Cut1 |
| M. vanbaalenii PYR-1 | Mvan_5804 | - | 4e-51 | 48.65% (222) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1788|M.bovis_AF2122/97 ---------------------------MVTTWALLFAP------------
Rv1758|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4439|M.gilvum_PYR-GCK -------------MGLSECLSGVTAPGLALAAGLLLAPHAFAQPALTPAP
MMAR_2419|M.marinum_M ---------------------------MGNYSGMNASHVVRFLG-PAVIT
MUL_1597|M.ulcerans_Agy99 --------------------------------------------------
MAV_2169|M.avium_104 ---------------------------MGIFDGMFARHIVRSLGSALVMA
TH_0238|M.thermoresistible__bu -------------------------------LSRIGSAVGAALTTASLIT
MSMEG_0194|M.smegmatis_MC2_155 ------------------------------------MKWIRALG---VCC
MAB_3272c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_5804|M.vanbaalenii_PYR-1 ---------------------------------------MNIFSRWLAVA
MLBr_00099|M.leprae_Br4923 MVEKVPRKRHRVLAWTAALSMAAVVALAIVAVVILLRSAESPRSSLPPGV
Mb1788|M.bovis_AF2122/97 ---VPAASADPPDPTVSDGA-CPDVEVVFARGTGEPPGVGGIGE--DFID
Rv1758|M.tuberculosis_H37Rv ----------------------------------MP---GRFRE--DFID
Mflv_4439|M.gilvum_PYR-GCK GPAPPPIAAPAPEPLAAPVAGCPDVEIVFARGTTEAPGLGAMGQ--AFVE
MMAR_2419|M.marinum_M ACGLSASVFSAVAIPSASAEPCPDVEVVFARGTGEPPGLGPTGQ--AFVN
MUL_1597|M.ulcerans_Agy99 -------MFSAVAIPSASAEPCPDVEVVFARGTGEPPGLGPTGQ--AFVN
MAV_2169|M.avium_104 ASGVAASAVSGSVIPTAAAQ-CPDIQVVFARGTGEAPGVGPTGQ--AFVD
TH_0238|M.thermoresistible__bu GTVITSTVVAGTAVPAAAAQPCPDVQVVFARGTGEPPGVGPTGQ--AFID
MSMEG_0194|M.smegmatis_MC2_155 ASVAAPLSAMTAPQAFAAPESCADVEVIFARGTGEAPGVGPTGQ--AFID
MAB_3272c|M.abscessus_ATCC_199 ---------------------------MFARGTFEPPGVGGTGE--SFVN
Mvan_5804|M.vanbaalenii_PYR-1 ASVVAVTGGLPLAAAPAYAAPCPDVEVVFARGTFEPPGIGATGQ--AFVD
MLBr_00099|M.leprae_Br4923 LPIPSTAPHPRKPRPAFQDVSCPDVQLLVVPGTWESSLQDNPLDPVQFPD
. . : * :
Mb1788|M.bovis_AF2122/97 ALR--------SKIGEKSMGVYGVDYPATTD-----------FPTAMAGI
Rv1758|M.tuberculosis_H37Rv ALR--------SKIGEKSMGVYGVDYPATTD-----------FPTAMAGI
Mflv_4439|M.gilvum_PYR-GCK DLR--------SRLGGKTVGVYAVDYPASPD-----------FPTAVEGI
MMAR_2419|M.marinum_M SLR--------SHIGGRSLDVYPVNYPASDN-----------WDTGLDGI
MUL_1597|M.ulcerans_Agy99 SLR--------SHIGGRSLDVYPVNYPASDN-----------WDTGLDGI
MAV_2169|M.avium_104 ALH--------QRVGGRSFDVYPVNYPASDQ-----------WDTGIEGI
TH_0238|M.thermoresistible__bu ALR--------PRVGDRSLDVYAVNYPAIDV-----------WNTGIDGI
MSMEG_0194|M.smegmatis_MC2_155 ALR--------PRLGDRSVDVYPVNYPATDQ-----------WATGVDGV
MAB_3272c|M.abscessus_ATCC_199 ALR--------ARTKGKSVEVYPVEYPASLA-----------FATAADGV
Mvan_5804|M.vanbaalenii_PYR-1 SLR--------SRAGGRTVDVYAVNYPASFD-----------FATAADGV
MLBr_00099|M.leprae_Br4923 ALLRNSTMTIGQQFPTSRVQTYTIPYTAQFHNPLSGDKQMTYNDSRAEGT
* : . .* : *.* : *
Mb1788|M.bovis_AF2122/97 YDAGTHVEQTAANCPQSKLVLGGFSQGAAVMGFVTAAA------------
Rv1758|M.tuberculosis_H37Rv YDAGTHVEQTAANCPQSKLVLGGFSQGAAVMGFVTAAA------------
Mflv_4439|M.gilvum_PYR-GCK ADASTHVQQIAMNCPDTKLVLGGYSQGAAVMGFVTTEL------------
MMAR_2419|M.marinum_M RDAGTHVVSMAGQCPQTKMVLGGYSQGAAVMGFVTSAA------------
MUL_1597|M.ulcerans_Agy99 RDAGTHVVSMAGQCPQTKMVLGGYSQGTAVMSFVTSAA------------
MAV_2169|M.avium_104 RDAGAHVNSMAHDCPNTKMVLGGYSQGAAVMGFVTSAS------------
TH_0238|M.thermoresistible__bu RDAGAHVVRMAEQCPDTRLVLGGFSQGAAVMGFVTSAE------------
MSMEG_0194|M.smegmatis_MC2_155 RDASTRIISMAETCPQTEMVLGGYSQGAAVAGFVTSAA------------
MAB_3272c|M.abscessus_ATCC_199 IDASNRVKDVAARCPNTKIVMGGFSQGAAVVAYTTADA------------
Mvan_5804|M.vanbaalenii_PYR-1 IDASNRVVTMAANCPDTQLVLGGFSQGAAVAAYITEDT------------
MLBr_00099|M.leprae_Br4923 RAMVQEMINVNNKCPLTSYVLVGFSQGAVIAGDITSDIGNGHGPVDDDLV
.: ** : *: *:***:.: . *
Mb1788|M.bovis_AF2122/97 -----IPDGAPL--DAPRPMPPEVADHVAAVTLFGMPSVAFMHSIG--AP
Rv1758|M.tuberculosis_H37Rv -----IPDGAPL--DAPRPMPPEVADHVAAVTLFGMPSVAFMHSIG--AP
Mflv_4439|M.gilvum_PYR-GCK -----IPDGVSLS-EVPAPMPPDIADHVAAVALLGAPSDRFMDMIK--QP
MMAR_2419|M.marinum_M -----VPAGVDPA-TVPKPLQPDVAEHVAAVVLFGMPNVRAMDFLG--EP
MUL_1597|M.ulcerans_Agy99 -----VPAGVDPA-TVPKPLQPDVAEHVAAVVLFGMPNVRAMNFLG--EP
MAV_2169|M.avium_104 -----VPDGVDPN-TVPKPLDPEVANHVSSVVLFGMPNVRAMNFLN--EP
TH_0238|M.thermoresistible__bu -----VPAGVDPA-TVPKPLDPDIAEHVAAVVLFGMPNARAMNFLG--TP
MSMEG_0194|M.smegmatis_MC2_155 -----VPDGVDPA-TVPKPLQPDIADHVAAVVLFGLPNERAMNFLG--EP
MAB_3272c|M.abscessus_ATCC_199 -----VPPGFELPEGITGPMPAEVADHVAAVALFGKPSSGFLQRIDNTAP
Mvan_5804|M.vanbaalenii_PYR-1 -----IPEGYTPPPGMTGPMPPSVADNVAAVALFGKPSSGFLQMIYTGAP
MLBr_00099|M.leprae_Br4923 LGVTLIADGRRQQ-GVGNDIGPNPPGEGAEVTLHEVPVLSGLGMTMTGAR
:. * : .. . . : *.* * :
Mb1788|M.bovis_AF2122/97 PIVIGPLYAEKTIQLCAPGDPVCS-------------------SGGNWAA
Rv1758|M.tuberculosis_H37Rv PIVIGPLYAEKTIQLCAPGDPVCS-------------------SGGNWAA
Mflv_4439|M.gilvum_PYR-GCK PVTIGALYQPKTLELCVPGDFVCS-------------------PGNDLGA
MMAR_2419|M.marinum_M AVEIGPAYQAKTIKVCVPEDPVCS-------------------DGLNFAA
MUL_1597|M.ulcerans_Agy99 AVEIGPAYQAKTIKVCVPEDPVCS-------------------DGLNFAA
MAV_2169|M.avium_104 PVVIGPAYQDKTLKVCATEDPVCS-------------------DGMNFAA
TH_0238|M.thermoresistible__bu PVVIGPLYEDKTVKLCAVDDPVCS-------------------NGMNFAA
MSMEG_0194|M.smegmatis_MC2_155 RVVIGPLYETKTRTYCATEDPVCS-------------------DGLNFAV
MAB_3272c|M.abscessus_ATCC_199 PINIGHLYVAKTMDMCVPEDPICSP------------------DGSDNAA
Mvan_5804|M.vanbaalenii_PYR-1 PINVGSRYAAKTLDLCIPEDPVCSP------------------TGRDNAA
MLBr_00099|M.leprae_Br4923 PGGFG-VLHSRTNEICAPGDLICAAPAEAFSVANLPATLNTLASGAGQPI
.* :* * * :*: * .
Mb1788|M.bovis_AF2122/97 HNGYADDG-MVEQAAVFAAGRLG------------------
Rv1758|M.tuberculosis_H37Rv HNGYADDG-MVEQAAVFAAGRLG------------------
Mflv_4439|M.gilvum_PYR-GCK HARYISDG-LVVQAADFAVGKLAETPAESGGAPA-------
MMAR_2419|M.marinum_M HNAYADDGAVVDQGVAFAASRLGGDPGGPVPAPSSG--FGN
MUL_1597|M.ulcerans_Agy99 HNAYADDGAVVDQGVAFAASRLGGDPGGPVPAPSSG--FGN
MAV_2169|M.avium_104 HNTYANDNEMIDKGVAFASSHLGLGGPATVAAPSGGG-FGS
TH_0238|M.thermoresistible__bu HNTYATNAAMVDQGAAFAADRLGVASDKPLPTPSSGQNFGN
MSMEG_0194|M.smegmatis_MC2_155 HNPSSYDGDLTDQGAAFAADRINTG---PVTATN-------
MAB_3272c|M.abscessus_ATCC_199 HGSYGDNG-MTSQAADFAARQIN-----SPTDTVSAAG---
Mvan_5804|M.vanbaalenii_PYR-1 HGGYALTG-MTDRAAEFAVRNMPRHGSEQPVDLAAGPR---
MLBr_00099|M.leprae_Br4923 HAMYATAQFWDLDGAPATVWTLNWVHRLIEGAPHPKHG---
* .. : :