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FSAVAIPSASAEPCPDVEVVFARGTGEPPGLGPTGQAFVNSLRSHIGGRSLDVYPVNYPASDNWDTGLDG IRDAGTHVVSMAGQCPQTKMVLGGYSQGTAVMSFVTSAAVPAGVDPATVPKPLQPDVAEHVAAVVLFGMP NVRAMNFLGEPAVEIGPAYQAKTIKVCVPEDPVCSDGLNFAAHNAYADDGAVVDQGVAFAASRLGGDPGG PVPAPSSGFGN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1597 | cut1 | - | 100% (222) | cutinase Cut1 |
| M. ulcerans Agy99 | MUL_4327 | cut5 | 3e-60 | 53.55% (211) | cutinase, Cut5 |
| M. ulcerans Agy99 | MUL_0855 | cut4 | 6e-41 | 44.72% (199) | cutinase precursor, Cut4 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1788 | cut1 | 2e-66 | 57.89% (209) | cutinase Cut1 |
| M. gilvum PYR-GCK | Mflv_4439 | - | 2e-58 | 52.07% (217) | cutinase |
| M. tuberculosis H37Rv | Rv1758 | cut1 | 1e-52 | 57.74% (168) | cutinase Cut1 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3272c | - | 3e-46 | 48.68% (189) | cutinase Cut1 |
| M. marinum M | MMAR_2419 | cut1 | 1e-127 | 98.65% (222) | cutinase Cut1 |
| M. avium 104 | MAV_2169 | - | 2e-90 | 71.49% (221) | serine esterase cutinase |
| M. smegmatis MC2 155 | MSMEG_0194 | - | 2e-83 | 69.38% (209) | serine esterase, cutinase family protein |
| M. thermoresistible (build 8) | TH_0238 | - | 2e-94 | 71.43% (224) | serine esterase, cutinase family protein |
| M. vanbaalenii PYR-1 | Mvan_5804 | - | 7e-54 | 51.71% (205) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1788|M.bovis_AF2122/97 ---------------MVTTWALLFAP--VPAASADPPDPT----------
Rv1758|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1597|M.ulcerans_Agy99 -------------------------------MFSAVAIPS----------
MMAR_2419|M.marinum_M MGNYSGMN-ASHVVRFLG-PAVITACGLSASVFSAVAIPS----------
MAV_2169|M.avium_104 MGIFDGMF-ARHIVRSLGSALVMAASGVAASAVSGSVIPT----------
TH_0238|M.thermoresistible__bu ----LSRI-GSAVGAALTTASLITGTVITSTVVAGTAVPA----------
MSMEG_0194|M.smegmatis_MC2_155 ----------MKWIRALG---VCCASVAAPLSAMTAPQAF----------
Mflv_4439|M.gilvum_PYR-GCK MGLSECLSGVTAPGLALAAGLLLAPHAFAQPALTPAPGPAPPPIAAPAPE
MAB_3272c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_5804|M.vanbaalenii_PYR-1 -------------MNIFSRWLAVAASVVAVTGGLPLAAAP----------
Mb1788|M.bovis_AF2122/97 ---VSDGACPDVEVVFARGTGEPPGVGGIGEDFIDALRSKIGEKSMGVYG
Rv1758|M.tuberculosis_H37Rv ---------------------MP---GRFREDFIDALRSKIGEKSMGVYG
MUL_1597|M.ulcerans_Agy99 ---ASAEPCPDVEVVFARGTGEPPGLGPTGQAFVNSLRSHIGGRSLDVYP
MMAR_2419|M.marinum_M ---ASAEPCPDVEVVFARGTGEPPGLGPTGQAFVNSLRSHIGGRSLDVYP
MAV_2169|M.avium_104 ---AAAQ-CPDIQVVFARGTGEAPGVGPTGQAFVDALHQRVGGRSFDVYP
TH_0238|M.thermoresistible__bu ---AAAQPCPDVQVVFARGTGEPPGVGPTGQAFIDALRPRVGDRSLDVYA
MSMEG_0194|M.smegmatis_MC2_155 ---AAPESCADVEVIFARGTGEAPGVGPTGQAFIDALRPRLGDRSVDVYP
Mflv_4439|M.gilvum_PYR-GCK PLAAPVAGCPDVEIVFARGTTEAPGLGAMGQAFVEDLRSRLGGKTVGVYA
MAB_3272c|M.abscessus_ATCC_199 --------------MFARGTFEPPGVGGTGESFVNALRARTKGKSVEVYP
Mvan_5804|M.vanbaalenii_PYR-1 ---AYAAPCPDVEVVFARGTFEPPGIGATGQAFVDSLRSRAGGRTVDVYA
. * : *:: *: : ::. **
Mb1788|M.bovis_AF2122/97 VDYPATTDFPTAMAGIYDAGTHVEQTAANCPQSKLVLGGFSQGAAVMGFV
Rv1758|M.tuberculosis_H37Rv VDYPATTDFPTAMAGIYDAGTHVEQTAANCPQSKLVLGGFSQGAAVMGFV
MUL_1597|M.ulcerans_Agy99 VNYPASDNWDTGLDGIRDAGTHVVSMAGQCPQTKMVLGGYSQGTAVMSFV
MMAR_2419|M.marinum_M VNYPASDNWDTGLDGIRDAGTHVVSMAGQCPQTKMVLGGYSQGAAVMGFV
MAV_2169|M.avium_104 VNYPASDQWDTGIEGIRDAGAHVNSMAHDCPNTKMVLGGYSQGAAVMGFV
TH_0238|M.thermoresistible__bu VNYPAIDVWNTGIDGIRDAGAHVVRMAEQCPDTRLVLGGFSQGAAVMGFV
MSMEG_0194|M.smegmatis_MC2_155 VNYPATDQWATGVDGVRDASTRIISMAETCPQTEMVLGGYSQGAAVAGFV
Mflv_4439|M.gilvum_PYR-GCK VDYPASPDFPTAVEGIADASTHVQQIAMNCPDTKLVLGGYSQGAAVMGFV
MAB_3272c|M.abscessus_ATCC_199 VEYPASLAFATAADGVIDASNRVKDVAARCPNTKIVMGGFSQGAAVVAYT
Mvan_5804|M.vanbaalenii_PYR-1 VNYPASFDFATAADGVIDASNRVVTMAANCPDTQLVLGGFSQGAAVAAYI
*:*** : *. *: **. :: * **::.:*:**:***:** .:
Mb1788|M.bovis_AF2122/97 TAAAIPDG--APLDAPRPMPPEVADHVAAVTLFGMPSVAFMHSIG--APP
Rv1758|M.tuberculosis_H37Rv TAAAIPDG--APLDAPRPMPPEVADHVAAVTLFGMPSVAFMHSIG--APP
MUL_1597|M.ulcerans_Agy99 TSAAVPAGV-DPATVPKPLQPDVAEHVAAVVLFGMPNVRAMNFLG--EPA
MMAR_2419|M.marinum_M TSAAVPAGV-DPATVPKPLQPDVAEHVAAVVLFGMPNVRAMDFLG--EPA
MAV_2169|M.avium_104 TSASVPDGV-DPNTVPKPLDPEVANHVSSVVLFGMPNVRAMNFLN--EPP
TH_0238|M.thermoresistible__bu TSAEVPAGV-DPATVPKPLDPDIAEHVAAVVLFGMPNARAMNFLG--TPP
MSMEG_0194|M.smegmatis_MC2_155 TSAAVPDGV-DPATVPKPLQPDIADHVAAVVLFGLPNERAMNFLG--EPR
Mflv_4439|M.gilvum_PYR-GCK TTELIPDGV-SLSEVPAPMPPDIADHVAAVALLGAPSDRFMDMIK--QPP
MAB_3272c|M.abscessus_ATCC_199 TADAVPPGFELPEGITGPMPAEVADHVAAVALFGKPSSGFLQRIDNTAPP
Mvan_5804|M.vanbaalenii_PYR-1 TEDTIPEGYTPPPGMTGPMPPSVADNVAAVALFGKPSSGFLQMIYTGAPP
* :* * . *: ..:*::*::*.*:* *. :. : *
Mb1788|M.bovis_AF2122/97 IVIGPLYAEKTIQLCAPGDPVCS-SGGNWAAHNGYADDG-MVEQAAVFAA
Rv1758|M.tuberculosis_H37Rv IVIGPLYAEKTIQLCAPGDPVCS-SGGNWAAHNGYADDG-MVEQAAVFAA
MUL_1597|M.ulcerans_Agy99 VEIGPAYQAKTIKVCVPEDPVCS-DGLNFAAHNAYADDGAVVDQGVAFAA
MMAR_2419|M.marinum_M VEIGPAYQAKTIKVCVPEDPVCS-DGLNFAAHNAYADDGAVVDQGVAFAA
MAV_2169|M.avium_104 VVIGPAYQDKTLKVCATEDPVCS-DGMNFAAHNTYANDNEMIDKGVAFAS
TH_0238|M.thermoresistible__bu VVIGPLYEDKTVKLCAVDDPVCS-NGMNFAAHNTYATNAAMVDQGAAFAA
MSMEG_0194|M.smegmatis_MC2_155 VVIGPLYETKTRTYCATEDPVCS-DGLNFAVHNPSSYDGDLTDQGAAFAA
Mflv_4439|M.gilvum_PYR-GCK VTIGALYQPKTLELCVPGDFVCS-PGNDLGAHARYISDG-LVVQAADFAV
MAB_3272c|M.abscessus_ATCC_199 INIGHLYVAKTMDMCVPEDPICSPDGSDNAAHGSYGDNG-MTSQAADFAA
Mvan_5804|M.vanbaalenii_PYR-1 INVGSRYAAKTLDLCIPEDPVCSPTGRDNAAHGGYALTG-MTDRAAEFAV
: :* * ** * * :** * : ..* : :.. **
Mb1788|M.bovis_AF2122/97 GRLG------------------
Rv1758|M.tuberculosis_H37Rv GRLG------------------
MUL_1597|M.ulcerans_Agy99 SRLGGDPGGPVPAPSSG--FGN
MMAR_2419|M.marinum_M SRLGGDPGGPVPAPSSG--FGN
MAV_2169|M.avium_104 SHLGLGGPATVAAPSGGG-FGS
TH_0238|M.thermoresistible__bu DRLGVASDKPLPTPSSGQNFGN
MSMEG_0194|M.smegmatis_MC2_155 DRINTG---PVTATN-------
Mflv_4439|M.gilvum_PYR-GCK GKLAETPAESGGAPA-------
MAB_3272c|M.abscessus_ATCC_199 RQIN-----SPTDTVSAAG---
Mvan_5804|M.vanbaalenii_PYR-1 RNMPRHGSEQPVDLAAGPR---
.: