For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
GIFDGMFARHIVRSLGSALVMAASGVAASAVSGSVIPTAAAQCPDIQVVFARGTGEAPGVGPTGQAFVDA LHQRVGGRSFDVYPVNYPASDQWDTGIEGIRDAGAHVNSMAHDCPNTKMVLGGYSQGAAVMGFVTSASVP DGVDPNTVPKPLDPEVANHVSSVVLFGMPNVRAMNFLNEPPVVIGPAYQDKTLKVCATEDPVCSDGMNFA AHNTYANDNEMIDKGVAFASSHLGLGGPATVAAPSGGGFGS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2169 | - | - | 100% (252) | serine esterase cutinase |
| M. avium 104 | MAV_2961 | - | 2e-61 | 54.41% (204) | cutinase Cut3 |
| M. avium 104 | MAV_0369 | - | 1e-54 | 48.66% (224) | serine esterase cutinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1788 | cut1 | 8e-62 | 55.73% (192) | cutinase Cut1 |
| M. gilvum PYR-GCK | Mflv_4439 | - | 3e-57 | 48.65% (222) | cutinase |
| M. tuberculosis H37Rv | Rv1758 | cut1 | 1e-50 | 53.57% (168) | cutinase Cut1 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3272c | - | 2e-42 | 46.56% (189) | cutinase Cut1 |
| M. marinum M | MMAR_2419 | cut1 | 3e-98 | 69.17% (253) | cutinase Cut1 |
| M. smegmatis MC2 155 | MSMEG_0194 | - | 2e-81 | 63.80% (221) | serine esterase, cutinase family protein |
| M. thermoresistible (build 8) | TH_0238 | - | 2e-92 | 65.83% (240) | serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_1597 | cut1 | 2e-90 | 71.49% (221) | cutinase Cut1 |
| M. vanbaalenii PYR-1 | Mvan_5793 | - | 4e-50 | 47.71% (218) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3272c|M.abscessus_ATCC_199 --------------------------------------------------
Mvan_5793|M.vanbaalenii_PYR-1 ------MKMSRVAGIAGAVALGACS-------------------AVTGLG
Mb1788|M.bovis_AF2122/97 --------------MVTTWALLFAP---------------VPAASADPPD
Rv1758|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_4439|M.gilvum_PYR-GCK MGLSECLSGVTAPGLALAAGLLLAPHAFAQPALTPAPGPAPPPIAAPAPE
MMAR_2419|M.marinum_M MGNYSGMNASHVVRFLG-PAVITAC--------------GLSASVFSAVA
MUL_1597|M.ulcerans_Agy99 --------------------------------------------MFSAVA
MAV_2169|M.avium_104 MGIFDGMFARHIVRSLGSALVMAAS--------------GVAASAVSGSV
TH_0238|M.thermoresistible__bu ----LSRIGSAVGAALTTASLITGT--------------VITSTVVAGTA
MSMEG_0194|M.smegmatis_MC2_155 ---------MKWIRALG---VCCAS--------------VAAPLSAMTAP
MAB_3272c|M.abscessus_ATCC_199 --------------MFARGTFEPPGVGGTGESFVNALRARTKGKSVEVYP
Mvan_5793|M.vanbaalenii_PYR-1 APSAAAQPCPDVEVVFARGTSEPPGVGGVGQAFVDALRAQAAPRTVGVYA
Mb1788|M.bovis_AF2122/97 PTVSDGA-CPDVEVVFARGTGEPPGVGGIGEDFIDALRSKIGEKSMGVYG
Rv1758|M.tuberculosis_H37Rv ---------------------MP---GRFREDFIDALRSKIGEKSMGVYG
Mflv_4439|M.gilvum_PYR-GCK PLAAPVAGCPDVEIVFARGTTEAPGLGAMGQAFVEDLRSRLGGKTVGVYA
MMAR_2419|M.marinum_M IPSASAEPCPDVEVVFARGTGEPPGLGPTGQAFVNSLRSHIGGRSLDVYP
MUL_1597|M.ulcerans_Agy99 IPSASAEPCPDVEVVFARGTGEPPGLGPTGQAFVNSLRSHIGGRSLDVYP
MAV_2169|M.avium_104 IPTAAAQ-CPDIQVVFARGTGEAPGVGPTGQAFVDALHQRVGGRSFDVYP
TH_0238|M.thermoresistible__bu VPAAAAQPCPDVQVVFARGTGEPPGVGPTGQAFIDALRPRVGDRSLDVYA
MSMEG_0194|M.smegmatis_MC2_155 QAFAAPESCADVEVIFARGTGEAPGVGPTGQAFIDALRPRLGDRSVDVYP
. * : *:: *: : ::. **
MAB_3272c|M.abscessus_ATCC_199 VEYPAS------LAFA-TAADGVIDASNRVKDVAARCPNTKIVMGGFSQG
Mvan_5793|M.vanbaalenii_PYR-1 VNYPAANNFTDRAAFAGTVIDGIRDASNRLQAMSVNCPNTRLVLGGFSQG
Mb1788|M.bovis_AF2122/97 VDYPAT------TDFP-TAMAGIYDAGTHVEQTAANCPQSKLVLGGFSQG
Rv1758|M.tuberculosis_H37Rv VDYPAT------TDFP-TAMAGIYDAGTHVEQTAANCPQSKLVLGGFSQG
Mflv_4439|M.gilvum_PYR-GCK VDYPAS------PDFP-TAVEGIADASTHVQQIAMNCPDTKLVLGGYSQG
MMAR_2419|M.marinum_M VNYPAS------DNWD-TGLDGIRDAGTHVVSMAGQCPQTKMVLGGYSQG
MUL_1597|M.ulcerans_Agy99 VNYPAS------DNWD-TGLDGIRDAGTHVVSMAGQCPQTKMVLGGYSQG
MAV_2169|M.avium_104 VNYPAS------DQWD-TGIEGIRDAGAHVNSMAHDCPNTKMVLGGYSQG
TH_0238|M.thermoresistible__bu VNYPAI------DVWN-TGIDGIRDAGAHVVRMAEQCPDTRLVLGGFSQG
MSMEG_0194|M.smegmatis_MC2_155 VNYPAT------DQWA-TGVDGVRDASTRIISMAETCPQTEMVLGGYSQG
*:*** : * *: **. :: : **::.:*:**:***
MAB_3272c|M.abscessus_ATCC_199 AAVVAYTTADAVPPGFELPEGITGPMPAEVADHVAAVALFGKPSSGFLQR
Mvan_5793|M.vanbaalenii_PYR-1 AVVSGFTTSDTVPSSVPAAAAPT-PLPPKVAEHVAAVVLFGAPSGSFMEK
Mb1788|M.bovis_AF2122/97 AAVMGFVTAAAIPDGAPL-DAPR-PMPPEVADHVAAVTLFGMPSVAFMHS
Rv1758|M.tuberculosis_H37Rv AAVMGFVTAAAIPDGAPL-DAPR-PMPPEVADHVAAVTLFGMPSVAFMHS
Mflv_4439|M.gilvum_PYR-GCK AAVMGFVTTELIPDGVSLSEVPA-PMPPDIADHVAAVALLGAPSDRFMDM
MMAR_2419|M.marinum_M AAVMGFVTSAAVPAGVDPATVPK-PLQPDVAEHVAAVVLFGMPNVRAMDF
MUL_1597|M.ulcerans_Agy99 TAVMSFVTSAAVPAGVDPATVPK-PLQPDVAEHVAAVVLFGMPNVRAMNF
MAV_2169|M.avium_104 AAVMGFVTSASVPDGVDPNTVPK-PLDPEVANHVSSVVLFGMPNVRAMNF
TH_0238|M.thermoresistible__bu AAVMGFVTSAEVPAGVDPATVPK-PLDPDIAEHVAAVVLFGMPNARAMNF
MSMEG_0194|M.smegmatis_MC2_155 AAVAGFVTSAAVPDGVDPATVPK-PLQPDIADHVAAVVLFGLPNERAMNF
:.* .:.*: :* . *: ..:*:**::*.*:* *. :.
MAB_3272c|M.abscessus_ATCC_199 IDNTAPPINIGHLYVAKTMDMCVPEDPICS--PDGSDNAAHGSYGDNG-M
Mvan_5793|M.vanbaalenii_PYR-1 YG--APAVTVGPLYADRTVELCAAGDSICDGAPNGGPNLAHALYPVNG-M
Mb1788|M.bovis_AF2122/97 IG--APPIVIGPLYAEKTIQLCAPGDPVCS---SGGNWAAHNGYADDG-M
Rv1758|M.tuberculosis_H37Rv IG--APPIVIGPLYAEKTIQLCAPGDPVCS---SGGNWAAHNGYADDG-M
Mflv_4439|M.gilvum_PYR-GCK IK--QPPVTIGALYQPKTLELCVPGDFVCS---PGNDLGAHARYISDG-L
MMAR_2419|M.marinum_M LG--EPAVEIGPAYQAKTIKVCVPEDPVCS---DGLNFAAHNAYADDGAV
MUL_1597|M.ulcerans_Agy99 LG--EPAVEIGPAYQAKTIKVCVPEDPVCS---DGLNFAAHNAYADDGAV
MAV_2169|M.avium_104 LN--EPPVVIGPAYQDKTLKVCATEDPVCS---DGMNFAAHNTYANDNEM
TH_0238|M.thermoresistible__bu LG--TPPVVIGPLYEDKTVKLCAVDDPVCS---NGMNFAAHNTYATNAAM
MSMEG_0194|M.smegmatis_MC2_155 LG--EPRVVIGPLYETKTRTYCATEDPVCS---DGLNFAVHNPSSYDGDL
* : :* * :* *. * :*. * .* : :
MAB_3272c|M.abscessus_ATCC_199 TSQAADFAARQINSPTDTVSAAG--------
Mvan_5793|M.vanbaalenii_PYR-1 VGQGASYAAGRL-------------------
Mb1788|M.bovis_AF2122/97 VEQAAVFAAGRLG------------------
Rv1758|M.tuberculosis_H37Rv VEQAAVFAAGRLG------------------
Mflv_4439|M.gilvum_PYR-GCK VVQAADFAVGKLAETPAESGGAPA-------
MMAR_2419|M.marinum_M VDQGVAFAASRLGGDPGGPVPAPSSG--FGN
MUL_1597|M.ulcerans_Agy99 VDQGVAFAASRLGGDPGGPVPAPSSG--FGN
MAV_2169|M.avium_104 IDKGVAFASSHLGLGGPATVAAPSGGG-FGS
TH_0238|M.thermoresistible__bu VDQGAAFAADRLGVASDKPLPTPSSGQNFGN
MSMEG_0194|M.smegmatis_MC2_155 TDQGAAFAADRINTG---PVTATN-------
:.. :* ::