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STSLAQRVVAGLKDKIFAGDLPPGHKLPSEAELIDEFGVSRTVVREAVTRLRAEGLIETFQGRGSFVLAV PEPTAFTIESAAIRTQRDVLDMVDFRLGVECEAAALAAARIDARGRDAVRTALDEFVGAAPEDAVEADFR FHRTIAEVSGNRFYLDLLNSLGPMMIMLPRTRLGDAHSITDAAHAERVRREHDQVAAAVAAGDPDLARAA MRLHLGNTRRRLAGDR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0124 | - | - | 100% (227) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_3822 | - | 1e-17 | 31.28% (227) | regulatory protein GntR, HTH |
| M. smegmatis MC2 155 | MSMEG_2794 | - | 3e-16 | 28.85% (208) | transcriptional regulator, GntR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0505 | - | 1e-14 | 29.28% (222) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4061 | - | 1e-17 | 33.04% (224) | regulatory protein GntR, HTH |
| M. tuberculosis H37Rv | Rv0494 | - | 1e-14 | 29.28% (222) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2272c | - | 2e-15 | 29.38% (211) | putative transcriptional regulator, GntR |
| M. marinum M | MMAR_0749 | - | 8e-19 | 31.86% (226) | GntR family transcriptional regulator |
| M. avium 104 | MAV_2542 | - | 2e-14 | 29.13% (230) | regulatory protein GntR, HTH |
| M. thermoresistible (build 8) | TH_4115 | - | 2e-19 | 33.94% (221) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1381 | - | 2e-19 | 32.16% (227) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_2282 | - | 3e-17 | 33.48% (227) | regulatory protein GntR, HTH |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4061|M.gilvum_PYR-GCK -MAAPDPADS------------------------------SD--------
Mvan_2282|M.vanbaalenii_PYR-1 MSAVPEPTDERLREEQTASDERLREEQTASDERLREEQTASDGADATAEQ
MSMEG_0124|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0749|M.marinum_M --------------------------------------------------
MUL_1381|M.ulcerans_Agy99 --------------------------------------------------
MAB_2272c|M.abscessus_ATCC_199 --------------------------------------------------
Mb0505|M.bovis_AF2122/97 ----------------------------------------------MVEP
Rv0494|M.tuberculosis_H37Rv ----------------------------------------------MVEP
TH_4115|M.thermoresistible__bu --------------------------------------------------
MAV_2542|M.avium_104 -----------------------------------------MPKREPLAP
Mflv_4061|M.gilvum_PYR-GCK -ASEALLRPVRPLNAFEDTVERLLQTIRLGVLTPGESLPPERELAARLGV
Mvan_2282|M.vanbaalenii_PYR-1 IAADALLRPVRPLNAFEDTVERLLQTIRLGVLRPGESLPPERELATRLGV
MSMEG_0124|M.smegmatis_MC2_155 ----------MSTSLAQRVVAGLKDKIFAGDLPPGHKLPSEAELIDEFGV
MMAR_0749|M.marinum_M ------MQTVRRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCEMTGT
MUL_1381|M.ulcerans_Agy99 ---------MRRRTLIAQVSDQLRDEITSGRWKVGDRIPTEPELCEMTGT
MAB_2272c|M.abscessus_ATCC_199 ------MQPVRRQTLIGQVTEQLREEIVSGRWAIGARIPTEPELCELTGT
Mb0505|M.bovis_AF2122/97 MNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPERDLAERLGV
Rv0494|M.tuberculosis_H37Rv MNQSSVFQPPDRQRVDERIATTIADAILDGVFPPGSTLPPERDLAERLGV
TH_4115|M.thermoresistible__bu -----------VQSSYIQVADQLRDLILRGDLAVGQKLPSEAEMAPLLGV
MAV_2542|M.avium_104 MATSQNNGAVRSPKTAEIVADTLRRMIVEGQLKDGDFLPYEAELMDHFQV
: * * * :* * :: .
Mflv_4061|M.gilvum_PYR-GCK SRDTVREAIKSLADAGYLVSRRGRYGGTFLADALPA-----PRADGTEMH
Mvan_2282|M.vanbaalenii_PYR-1 SRDTVREAIKSLADAGYLVSRRGRYGGTFIADALPA-----PRTGDVAFS
MSMEG_0124|M.smegmatis_MC2_155 SRTVVREAVTRLRAEGLIETFQGRGSFVLAVPEPTA-----FTIESAAIR
MMAR_0749|M.marinum_M ARNTVREAVQALVHVGILERRQGSGTYVIADVEQGS-----ALAEYFAAA
MUL_1381|M.ulcerans_Agy99 ARNTVREAVQALVHVGILERRQGSGTYVIADVEQGS-----ALAEYFAAA
MAB_2272c|M.abscessus_ATCC_199 SRNTIREAVQALVHAGMLERRQGSGTYVLS-LGGSS-----AIADYFAAA
Mb0505|M.bovis_AF2122/97 NRTSLRQGLARLQQMGLIEVRHGSGSVVRDPEGLTH-----PAVVEALVR
Rv0494|M.tuberculosis_H37Rv NRTSLRQGLARLQQMGLIEVRHGSGSVVRDPEGLTH-----PAVVEALVR
TH_4115|M.thermoresistible__bu SRSTIREALRILTTEHLIETRRGIQGGAFVAVPDSERLEGMFNTSFSMLA
MAV_2542|M.avium_104 SRPSLREAVRVLESDRLVEVRRGSRTGARVRVPGPE----IVARPAGFLL
* :*:.: * : :* .
Mflv_4061|M.gilvum_PYR-GCK RD---DIDDAVRLREILEVGAARMAAVRT--LAAVEREALRSRLTDVRGA
Mvan_2282|M.vanbaalenii_PYR-1 RT---DIDDALRLREILETGAARMAACRT--LSATEREALWSRLLDVRGA
MSMEG_0124|M.smegmatis_MC2_155 TQR--DVLDMVDFRLGVECEAAALAAAR---IDARGRDAVRTALDEFVGA
MMAR_0749|M.marinum_M RE-----RDLWELREAVEVTAAVLSARRRDAADIEDLRALLARRNELWSR
MUL_1381|M.ulcerans_Agy99 RE-----RDLWELREAVEVTAAVLSARRRDAADIEDLRVLLARRNELWSR
MAB_2272c|M.abscessus_ATCC_199 NN-----RDLIELRQTLEVTAAGLAAQRRDEDDIEQLRALLVRRNELWAP
Mb0505|M.bovis_AF2122/97 KLGPDFLVELLEIRAALGPLIGRLAAARS---TPEDAEALCAALEVVQQA
Rv0494|M.tuberculosis_H37Rv KLGPDFLVELLEIRAALGPLIGRLAAARS---TPEDAEALCAALEVVQQA
TH_4115|M.thermoresistible__bu LTNQVDARSFLQAMRALEGPAAALAAAAR---GGDQVEELKRTAAMVDPA
MAV_2542|M.avium_104 EMAGTTLADVMTARMGIEPYAARLLAEDG---TAAAHRELRELIEEIPAA
. : . : * : .
Mflv_4061|M.gilvum_PYR-GCK DPADYR-RLDSRLHLAIAEAAG---VPSLVPLVAQNRMRLNELLDRIPLM
Mvan_2282|M.vanbaalenii_PYR-1 APQDYR-RLDSRLHLAITEAAG---VPSLVPLVAQNRMRLNEMLDCIPLL
MSMEG_0124|M.smegmatis_MC2_155 APEDAV-EADFRFHRTIAEVSGNRFYLDLLNSLGPMMIMLPRTRLGDAHS
MMAR_0749|M.marinum_M EPANDK-ERTEMTSADTALHRAIVAASHNEIYLQFYDLLLPTIHRAVEAG
MUL_1381|M.ulcerans_Agy99 EPANDK-ERTEMTSADTALHRAIVAASHNETYLQFYDLLLPTIHRAVEAG
MAB_2272c|M.abscessus_ATCC_199 HHVEPH-NVEEAISTDIAVHRAVVAASHNALYLELYDSLLGLMDHYMRGN
Mb0505|M.bovis_AF2122/97 DTAAAR-QAADLAYFRVLIHSTR--NRALGLLYRWVEHAFGGREHALTGA
Rv0494|M.tuberculosis_H37Rv DTAAAR-QAADLAYFRVLIHSTR--NRALGLLYRWVEHAFGGREHALTGA
TH_4115|M.thermoresistible__bu DQEAAM-QQSADFHSAILRASGN----KLLEAMGRPVSAVARSKFRRTVP
MAV_2542|M.avium_104 WETGKLGAASTALHRRLVELSGNATLTVIVGMLHEIFERHMTAAFLSVQN
Mflv_4061|M.gilvum_PYR-GCK TRNIAHSD---EQHEAIVSAILAGDADTAAQTMAAHVWGSAALLHGFLD-
Mvan_2282|M.vanbaalenii_PYR-1 PRNIAHSD---EQHEAIVMAILAGDADGAAQTMAAHVWGSAALLHGFLD-
MSMEG_0124|M.smegmatis_MC2_155 ITDAAHAERVRREHDQVAAAVAAGDPDLARAAMRLHLGNTRRRLAGDR--
MMAR_0749|M.marinum_M PVGTCTSY--EREHTELVEAIIAGDPQRAEAAAQVFIARLRP--------
MUL_1381|M.ulcerans_Agy99 PVGTCTSY--EREHTELVEAIIAGDPQRAEAAAQVFIARLRR--------
MAB_2272c|M.abscessus_ATCC_199 PIGAECSF--EHEHTRLVESVIAGDIGGATSATEQLFAELRLSRDQPGRN
Mb0505|M.bovis_AF2122/97 YDDADPVL---TDLRAINGAVLAGDPAAAAATVEAYLNASALRMVKSYRD
Rv0494|M.tuberculosis_H37Rv YDDADPVL---TDLRAINGAVLAGDPAAAAATVEAYLNASALRMVKSYRD
TH_4115|M.thermoresistible__bu GLEFWERN--QRAHQELLKAILAGDENLAYELATRHIDEDLSPYYLPPEE
MAV_2542|M.avium_104 VVPKAQYNKLMRSYTRLADLVAARDGAEAEAHWRRHMENASAELLKGHEK
: : * * * .
Mflv_4061|M.gilvum_PYR-GCK --------
Mvan_2282|M.vanbaalenii_PYR-1 --------
MSMEG_0124|M.smegmatis_MC2_155 --------
MMAR_0749|M.marinum_M --------
MUL_1381|M.ulcerans_Agy99 --------
MAB_2272c|M.abscessus_ATCC_199 FPHHPHD-
Mb0505|M.bovis_AF2122/97 RA------
Rv0494|M.tuberculosis_H37Rv RA------
TH_4115|M.thermoresistible__bu ADRDGAGA
MAV_2542|M.avium_104 TKVRDIMH