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AAPLGGARPLGERAGGRHRPAREGYPAVIWLLLGGNLVVRAAGFAYPFMAFHVAGRGFAAAAVGAVLAAF GVGWAVGQLVCGWLVDSLGPRATLAWTMTIAAGVLVGMAEARSVAALLVGAMITGMVYDAPRPVMGAAIA ELIPEPSRRAKLDAWRFGWIVSIGRAITGGVGGLLAAWSGVPVLFWINAVACALLALVAARCIPATAHRP PVAPAVHVRAARISYRRAFSDGRLVLLFASSLATLTAVRGLYATVPMLMADSGLGAGEFGWTQVANAAAG IGLTPVITPWLGRKVAARINPRLDILAIAGGWTALTMAGAALAHTTFGFAIAVAASAPGEIAWFVIAAGI VHRIAPPASGGRYHGIWSMTLAIASVVAPIVSSCSLTHGGHRLVALVTVTVGLAGAALCLPLARALNRSG DVGVRDSQYTAVAGAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4785 | - | - | 100% (437) | integral membrane protein |
| M. marinum M | MMAR_0690 | - | 5e-08 | 23.82% (382) | putative transport protein |
| M. marinum M | MMAR_1306 | - | 1e-05 | 24.45% (319) | transmembrane transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0865 | - | 1e-139 | 60.20% (402) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_1475 | - | 3e-11 | 27.21% (294) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv0842 | - | 1e-139 | 60.20% (402) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4615 | - | 2e-12 | 26.98% (189) | major facilitator transporter |
| M. avium 104 | MAV_4712 | - | 3e-08 | 24.94% (405) | transporter, major facilitator family protein |
| M. smegmatis MC2 155 | MSMEG_6245 | - | 2e-09 | 24.37% (398) | chloramphenicol resistance protein |
| M. thermoresistible (build 8) | TH_0476 | - | 5e-09 | 24.80% (383) | major facilitator superfamily protein MFS_1 |
| M. ulcerans Agy99 | MUL_0354 | - | 0.0 | 97.25% (437) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_5224 | - | 5e-11 | 26.67% (390) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4785|M.marinum_M --------------------------------------------------
MUL_0354|M.ulcerans_Agy99 MLTSGSMTTTATIAAGEAMRVSSSSSPDLPDAGDTTKFLRPRNAALRSKA
Mb0865|M.bovis_AF2122/97 --------------------------------------------------
Rv0842|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1475|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6245|M.smegmatis_MC2_155 --------------------------------------------------
TH_0476|M.thermoresistible__bu --------------------------------------------------
Mvan_5224|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4712|M.avium_104 --------------------------------------------------
MAB_4615|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_4785|M.marinum_M -----------------------------MAAPLGGA--RPLGERAGGRH
MUL_0354|M.ulcerans_Agy99 RGGSRSAARMANTKTNRKPRSARALCARAVAAPLGGA--RPLGERAGGRH
Mb0865|M.bovis_AF2122/97 ------------------------------MRYTGPE--RCSGD---GQV
Rv0842|M.tuberculosis_H37Rv ------------------------------MRYTGPE--RCSGD---GQV
Mflv_1475|M.gilvum_PYR-GCK ------------------------------MAPLSPTAQRAP--------
MSMEG_6245|M.smegmatis_MC2_155 -------------------------------MPFSLYP------------
TH_0476|M.thermoresistible__bu ------------------------------VRRFAFP-------------
Mvan_5224|M.vanbaalenii_PYR-1 ----------------------------MTVVAVAAATTRPSGR------
MAV_4712|M.avium_104 ------------------------------MTDSSPPAKGTFTVEMLS--
MAB_4615|M.abscessus_ATCC_1997 -------------------------------MPQRLSAWRFVTT------
MMAR_4785|M.marinum_M RPAREGYPAVIWLLLGGNLVVRAAGFAYPFMAFHVAGRGFAAAAVGAVLA
MUL_0354|M.ulcerans_Agy99 RPAREGYPAVIWLLLGGNLVVRAAGFAYPFMAFHVAGRGFAAAAVGAVLA
Mb0865|M.bovis_AF2122/97 RAAGDRYSTVIWLLGG-NLLVRSAGFGYPFLAYHVAGRGHGAGAVGAVVA
Rv0842|M.tuberculosis_H37Rv RAAGDRYSTVIWLLGG-NLLVRSAGFGYPFLAYHVAGRGHGAGAVGAVVA
Mflv_1475|M.gilvum_PYR-GCK ------------LLAAGFTTAFGAHAVAGTLGTTTTGTAASLLTLGAMLA
MSMEG_6245|M.smegmatis_MC2_155 ------------LAVAVFAMGTSEFMLAGLVPDIAADLGVSIGSAGLLTS
TH_0476|M.thermoresistible__bu -----------LLAYAFAAVMVGTTVPTPMYAVYAERLGFGVLTTTVVFA
Mvan_5224|M.vanbaalenii_PYR-1 -----SARRWLAVAAATFAIAWGGNEFTPLLVMYRTQDGFSALTVDLLLF
MAV_4712|M.avium_104 -------RAKRGVTAVFVAHGLLFASWAAHIPQVKAGLGLDDAALGTALF
MAB_4615|M.abscessus_ATCC_1997 ------------FGVISMLADIVYEGARSITGPLLASLGASALVVGVVTG
. .
MMAR_4785|M.marinum_M AFGVGWAVGQLVCGWLVDSLGPR-ATLAWTMTIAAGVLVGMAEARSVAAL
MUL_0354|M.ulcerans_Agy99 AFGVGWAVGQLVCGWLVDSLGPR-ATLAWTMTIAAGVLVGMAEARSVAAL
Mb0865|M.bovis_AF2122/97 AYGLGWAVGQLLCGWLVDRVGAR-VTLVSTMLVAAAVLVLMAGLHTVPGL
Rv0842|M.tuberculosis_H37Rv AYGLGWAVGQLLCGWLVDRVGAR-VTLVSTMLVAAAVLVLMAGLHTVPGL
Mflv_1475|M.gilvum_PYR-GCK IYDGAEVILKPLFGTLADRIGAR-TVLIAGLAVFAVASLSFAVADETAWL
MSMEG_6245|M.smegmatis_MC2_155 AFAVGMVVGAPSMAALTRRWRAR-VSLSAFLLTFALVHVLGAVTTSFGVL
TH_0476|M.thermoresistible__bu GYTAGVLFALVVFGRWSDALGRR-PMLLAGVGCAIVSALVFLIAGSVPQL
Mvan_5224|M.vanbaalenii_PYR-1 AYVLGIVPALLIGGPLSDRFGRRPLMLPAPVLAAVGSAILALGAQSAPVL
MAV_4712|M.avium_104 GAPLGSVLATLAGHWALPRWGSH-RLIPVTVAGYAAAGTTVGLARSGPAL
MAB_4615|M.abscessus_ATCC_1997 IGEAAALALRLVSGPLTDRTRKFWAWTISGYALTVVTVPFLGVSSVLWIA
.
MMAR_4785|M.marinum_M LVGAMITGMVYDAPRPVMGAAIAELIPEPSRRAKLDAWRFGWIVSIGRAI
MUL_0354|M.ulcerans_Agy99 LVGAMITGVVYDAPRPVMGAAIAELIPEPSRRAKLDAWRFGWIVSIGRAI
Mb0865|M.bovis_AF2122/97 LVGAMIAGLVCDAPRPVLGAVIAELVADPQRRAQLDGWRYGWVLNIGAAI
Rv0842|M.tuberculosis_H37Rv LVGAMIAGLVCDAPRPVLGAVIAELVADPQRRAQLDGWRYGWVLNIGAAI
Mflv_1475|M.gilvum_PYR-GCK WAARLGQGIGAAAFSPAASALVARLAPASGQGRAFG--TYGSYKSVGYTL
MSMEG_6245|M.smegmatis_MC2_155 LVTRLVAAVANAGFLAVALSTAATLVPAGRQGRGLAVLLAGTTLATIAGV
TH_0476|M.thermoresistible__bu IAARFVSGMSAGIFTGTATAAVIEAAPERRRSRAAAVATVANIG--GLGA
Mvan_5224|M.vanbaalenii_PYR-1 GVGRVFSGVALGLAMAVGGSWIKELSSPPWEDGDAGARRAAMSLTAGFGL
MAV_4712|M.avium_104 FAALALWGMFQGALDVAMNTQAGTVER--RAGAPMMARFHGMWSLGTLAG
MAB_4615|M.abscessus_ATCC_1997 ATLVIAERVGKAVRSPAKDTLLSHATAVTGRGKGFAVHEAMDQIGAITGP
. : . :
MMAR_4785|M.marinum_M TGGVGGLLAAWSGVPVLFWINAVACALLALVAARCIPATAHR-PPVAPAV
MUL_0354|M.ulcerans_Agy99 TGGVGGLLAAWSGVPVLFWINAVACALLALVAARCIPATAHR-PPVAPAV
Mb0865|M.bovis_AF2122/97 TGGVGGVVAGWLDTPVLYWINGIGCAIFAGLAGRCIPADVCRRTESGLRA
Rv0842|M.tuberculosis_H37Rv TGGVGGVVAGWLDTPVLYWINGIGCAIFAGLAGRCIPADVCRRTESGLRA
Mflv_1475|M.gilvum_PYR-GCK GPLIGGAIVTFGGLQALFAVMAALAAAVAVWAAVAVPR-------LAVLP
MSMEG_6245|M.smegmatis_MC2_155 PG--GAVLGTMLGWRATFWAIALLCLPAVVGIATALPAGAGR----AGWP
TH_0476|M.thermoresistible__bu GPLLAGILVQYAPWPLHLTFWVHIVLMVLAAAAIAVAPETSP------RT
Mvan_5224|M.vanbaalenii_PYR-1 GAGTAGVLAEWGPAPTVLPYAVNIAMALAAAVFVSTAPETRT---RHDSG
MAV_4712|M.avium_104 ALIGAACVGAGIGLTAQLTVLGAVVLLVVVMLTRRLLPDAAD--------
MAB_4615|M.abscessus_ATCC_1997 LLVAGMLALTHVNYLPTFAILALPGGATLLLLFWLRRRVPHP---ERYEH
.
MMAR_4785|M.marinum_M HVRAARISYRRAFSDGRLVLLFASSLATLTAVRGLYATVP-MLMADSGLG
MUL_0354|M.ulcerans_Agy99 HVRAAHNSYRRAFSDGRLVLLFASSLATLTAVRGLYATVP-MLMADSGLG
Mb0865|M.bovis_AF2122/97 CTAMSKVGYRQALSDKRLVLLAVSGLATLTTLMGFFAAVP-MLMSASGLG
Rv0842|M.tuberculosis_H37Rv CTAMSKVGYRQALSDKRLVLLAVSGLATLTTLMGFFAAVP-MLMSASGLG
Mflv_1475|M.gilvum_PYR-GCK RTRQTLLDTVRRFSESSFVTPTLALAAATAALSAGVGFLP-VLGTDFGLS
MSMEG_6245|M.smegmatis_MC2_155 VAGASLCDELAQLGRKRLALAMLLAALVNAGTFATFTFLAPIVTESAGLG
TH_0476|M.thermoresistible__bu GRLGVQRLSLPPQVRKVFAIASLAAFAGFAVTGLFTAVAPSFLAEVIGVR
Mvan_5224|M.vanbaalenii_PYR-1 RPWWTDLAVPGASHRRFLLVVVPVAPWVFGAGATAYAVLPALMAGRVSSA
MAV_4712|M.avium_104 SVAAPPEPAAGRRVTPAVAILAAVSFASFLCEGAATDWSATYLRDVVGAG
MAB_4615|M.abscessus_ATCC_1997 DDYIRGAADRPHKLSLPLSFWLYSGFTAITMIGFATFGVLSFHMVQRGVL
. .
MMAR_4785|M.marinum_M AGEFGWTQVANAAAGIGLTP-VITPWLGRKVAARINPRLDILAIAGGWTA
MUL_0354|M.ulcerans_Agy99 AGEFGWAQVANAAAGIGLTP-VITPWLGRKVAARINPRLDILAIAGGWTA
Mb0865|M.bovis_AF2122/97 VGAYGWVQLINALAVVAVTP-LLTPWLSKQLA--LGPRPDILAGAGVWVT
Rv0842|M.tuberculosis_H37Rv VGAYGWVQLINALAVVAVTP-LLTPWLSKQLA--LGPRPDILAGAGVWVT
Mflv_1475|M.gilvum_PYR-GCK P-----VVTGAVVSVLALTT-AVVQPLAGRAADSGRISLTSGLFTGVVVT
MSMEG_6245|M.smegmatis_MC2_155 R-----LWVSVVLLLFGFGS-FIGVTVAGRLS---DTRPGIVIGAGGPAL
TH_0476|M.thermoresistible__bu N----HAVAGAVAASIFAAS-AVTQVLGASVS--PRRAVAVGCALLIVGM
Mvan_5224|M.vanbaalenii_PYR-1 P-----IAFSALMCLVALGVGFTVQQLGRHLGAGGRRGVVTALALLVVGM
MAV_4712|M.avium_104 P-------SVAAASYAAYTLTMVVTRFAAGRLHARLPSRRLLPALAVLAV
MAB_4615|M.abscessus_ATCC_1997 P-----VPAVPIVYAAAMAADAVAALLSGWAYDRVGPKS---LAALPIVG
..
MMAR_4785|M.marinum_M LTMAGAALAHTTFGFAIAVAASAPGEIAWFVIAAGIVHRIAPPASGGRYH
MUL_0354|M.ulcerans_Agy99 LTMAGAALAHTTFGFAIAVAASAAGEIAWFVIAVGTVHRIAPPASGGRYH
Mb0865|M.bovis_AF2122/97 LCMAAAGLARTTVGFSVAAAACSPGEIAWFVVAAGIVHRIAPPAHGGRYH
Rv0842|M.tuberculosis_H37Rv LCMAAAGLARTTVGFSVAAAACSPGEIAWFVVAAGIVHRIAPPAHGGRYH
Mflv_1475|M.gilvum_PYR-GCK AAGVAAAALPGLVGLLGGAVVIGVGCGLITPLAFTMLARSTPEERLGQTM
MSMEG_6245|M.smegmatis_MC2_155 LAGWAALALLSSQPVALLPLAFVQG-ALSFAVGSTLITRVLYEASAAPTM
TH_0476|M.thermoresistible__bu VFLAAALVWSSLPALIATAVVAGAGQGLSFSRGLAAVSARTPSDQRGEVS
Mvan_5224|M.vanbaalenii_PYR-1 LLAGWAAAVLTVWSALVAAAVLGAGYGMALLAGLQEIQRIAGPDDLAGLT
MAV_4712|M.avium_104 AGMSVTLATADAAAGVLGFAALGVGVALLVPTAFSAAYGARGAGSAIAIV
MAB_4615|M.abscessus_ATCC_1997 ATVPMLAFTDSLPGIVLGALLWGAAVGIQESTLRAVVADLVPPPRRATAY
.
MMAR_4785|M.marinum_M G--IWSMTLAIASVVAPIVSSCSLTHGGHRLVALVTVTVGLAGAALCLPL
MUL_0354|M.ulcerans_Agy99 G--IWSMTLAIASVVAPIVSSCSLTHGGHRLVALVTVTVGLAGAALCLP-
Mb0865|M.bovis_AF2122/97 G--IWSMAVAASSVAAPILAAFNLANGGRLVLAATTVTVGFFGAALCLPL
Rv0842|M.tuberculosis_H37Rv G--IWSMAVAASSVAAPILAAFNLANGGRLVLAATTVTVGFFGAALCLPL
Mflv_1475|M.gilvum_PYR-GCK G--AAEIGRECGDAAGPLVVAA--------IAAASTVPFGFLGLAAVVA-
MSMEG_6245|M.smegmatis_MC2_155 GGAYATAALNVGAAGGPVAAAAALGNHAN-VVAPVWVSSVMVALALLIAV
TH_0476|M.thermoresistible__bu S---TYFVVAYVALLVPVIGEGWAAHHWGLRTAGISFAVGVAVLAIGCLI
Mvan_5224|M.vanbaalenii_PYR-1 A---VFYSLSYLGFAVPAVLAFAVR------SFSYPAMFGFGAFAAAVCL
MAV_4712|M.avium_104 A----ATGWLGYLLGPPLIGHLSEWVGLSGALVTIPVMMTIVAVAIRYTP
MAB_4615|M.abscessus_ATCC_1997 G------VYAAVLGTATAIGGALTGYLYGVSIPMLIAVVGVIQLVALITA
. . . .
MMAR_4785|M.marinum_M ARALNRSGDVGVRDSQYTAVAGAA
MUL_0354|M.ulcerans_Agy99 ---LNRSGDVGVRDSQYTAVAAAA
Mb0865|M.bovis_AF2122/97 ARVLAAAS-CGPLSSKEPSRDSYQ
Rv0842|M.tuberculosis_H37Rv ARVLAAAS-CGPLSSKEPSRDSYQ
Mflv_1475|M.gilvum_PYR-GCK ------ASGVGVRRGRGRVGGVG-
MSMEG_6245|M.smegmatis_MC2_155 PMLKIVAPRPNPATSTPPLGGNCG
TH_0476|M.thermoresistible__bu AILIQESRDPQAI-----------
Mvan_5224|M.vanbaalenii_PYR-1 LVAVLGSRRTAAIS----------
MAV_4712|M.avium_104 AFDTADEFHRAPAG----------
MAB_4615|M.abscessus_ATCC_1997 APTLLRHAGQV-------------