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VPWQRPSSRIRELIREGARRALNAGPEWIEELDRETVSANPTIANDPVLAKVVKRANRANLVHWAAANVR HPGAPVPANLGGEPLRMARDLVRRGLETLTLDIYRIGQYIAWRLWINIAFDLTSDPQELRELLDVSAKSV NEFIEATLAGIAAQVQLEHDELTRGNHADRLEVVGHLLEGAPISRERAETRLGYSLIRAHTAAIIWSDDF DGDHSNLDRAADAFCHAVGSSQDLTVVANAATRWVWLAEATNLDIDTIEQAVDNASDARIAIGTKASGIE GFRRSHLEALTTQRTLARLKSDQRVAFFSDVQIVALITQNPQAADEFITSTLGELESAAPELQATLLMFI NEQCNASRAAKRLYTHRNTLLRRIEAAQRLLPRPLAHTSVHVAVALEALQWRGDNIAKLPTPTSQDDEVP A
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4242 | - | - | 100% (421) | transcriptional regulatory protein |
| M. marinum M | MMAR_1127 | - | e-145 | 62.07% (406) | hypothetical protein MMAR_1127 |
| M. marinum M | MMAR_2258 | - | e-140 | 61.87% (396) | transcriptional activator protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1226c | - | 0.0 | 75.77% (421) | hypothetical protein Mb1226c |
| M. gilvum PYR-GCK | Mflv_4621 | - | 1e-15 | 25.31% (403) | hypothetical protein Mflv_4621 |
| M. tuberculosis H37Rv | Rv1194c | - | 0.0 | 75.77% (421) | hypothetical protein Rv1194c |
| M. leprae Br4923 | MLBr_01052 | - | 1e-170 | 70.57% (418) | hypothetical protein MLBr_01052 |
| M. abscessus ATCC 19977 | MAB_2657c | - | 6e-75 | 36.97% (403) | hypothetical protein MAB_2657c |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0579 | - | 7e-07 | 28.57% (189) | helix-turn-helix, Fis-type |
| M. thermoresistible (build 8) | TH_3143 | - | 3e-21 | 24.94% (393) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0944 | - | 0.0 | 98.81% (421) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4621|M.gilvum_PYR-GCK -------------------------MLDSSEVQDTPGHAVHHLFRDLGDL
TH_3143|M.thermoresistible__bu -------------------------VVVSGYNADDISSTVALIVDRLLEN
MMAR_4242|M.marinum_M --------------------------MPWQRPSSRIRELIREGARRALNA
MUL_0944|M.ulcerans_Agy99 --------------------------MPWQRPSSRIRELIREGARRALNA
Mb1226c|M.bovis_AF2122/97 --------------------------MAWQQPSPRIRELIREGARIALNP
Rv1194c|M.tuberculosis_H37Rv --------------------------MAWQQPSPRIRELIREGARIALNP
MLBr_01052|M.leprae_Br4923 --------------------------MARQHPSPRVRELIREGARIALNP
MAB_2657c|M.abscessus_ATCC_199 ----------MNEGSERVHTQSMTPDQLWPDASEPVRRLIRELAEKMLAR
MSMEG_0579|M.smegmatis_MC2_155 MVSVSEVVGVRALGLRGVLMGRGDADIRWVATSELPDPTPFLEGGEILLT
Mflv_4621|M.gilvum_PYR-GCK V-----------RELPESIHGLLIEQV--AELAADQQLKELLSDTVAANV
TH_3143|M.thermoresistible__bu S-----------GEDVERIQRRILADI--DELRSDPRLVELLRSSVAGNV
MMAR_4242|M.marinum_M G-----------PEWIEELDRETVSAN--PTIANDPVLAKVVKRANRANL
MUL_0944|M.ulcerans_Agy99 G-----------PEWIEELDRETVSAN--PTIANDPVLAKVVKRVNRANL
Mb1226c|M.bovis_AF2122/97 S-----------PEWIEELDRATIAAN--PAIANDPVLAKVVQTANRANL
Rv1194c|M.tuberculosis_H37Rv S-----------PEWIEELDRATIAAN--PAIANDPVLAKVVQTANRANL
MLBr_01052|M.leprae_Br4923 T-----------QEWIDQLDRATFAAN--PAIANDPVLAKVVRRASRAHL
MAB_2657c|M.abscessus_ATCC_199 S-----------GEVAGDLTAASLEDPRYRTIADDPVIAEVDARLTVSNL
MSMEG_0579|M.smegmatis_MC2_155 TGIETRTWGREWDDYVRRLAGAAVAAVGFGIGLTHERTPTALIAACREHD
: : . . :
Mflv_4621|M.gilvum_PYR-GCK DTWFSV-VRHSIPFDRMESP------TAALEHARRMAQREVPVNALLRAY
TH_3143|M.thermoresistible__bu ETVLTV-IRYGIDLDRVEPP------TAALEYARRAAQHGIALSALIRAY
MMAR_4242|M.marinum_M VHWAAANVRHPGAPVPANLG------GEPLRMARDLVRRGLETLTLD-IY
MUL_0944|M.ulcerans_Agy99 VHWAAANVRHPGAPVPANLG------GEPLRMARDLVRRGLEALTLD-IY
Mb1226c|M.bovis_AF2122/97 VYWAAANLRDPGARVPANLG------TEPLRMARDLVRRGLDTVAFN-IY
Rv1194c|M.tuberculosis_H37Rv VYWAAANLRDPGARVPANLG------TEPLRMARDLVRRGLDTVAFN-IY
MLBr_01052|M.leprae_Br4923 VHWATANLRDPGAPVPAHLG------PEPLTMARDLVRRGRDVLALD-IY
MAB_2657c|M.abscessus_ATCC_199 KHWLTSNISEPGHRVRPATG------SAMRTYARDVVLRGLTTDDIQ-SW
MSMEG_0579|M.smegmatis_MC2_155 VNLFEVPRRTTFVAISREVARLLSEQESAATQAALQTQRKLISAATKRHP
* . :
Mflv_4621|M.gilvum_PYR-GCK RLGHQYGLNLIIAGLRSADLPPEEKLALIEHITRVSFRYIDWMSEQVLET
TH_3143|M.thermoresistible__bu RLGQQEMLERILREVRETELDPDLRLSVYERISSTSFAYIDWISQQVSDT
MMAR_4242|M.marinum_M RIGQYIAWRLWINIAFDLTSDPQELRELLDVSAKSVNEFIEATLAGIAAQ
MUL_0944|M.ulcerans_Agy99 RIGQYIAWRLWINIAFDLTSDPQELHELLDVSAKSVNEFIEATLAGIAAQ
Mb1226c|M.bovis_AF2122/97 RTGEHIGWRFWMGIAFELTSDPQELRELLDVSARSVNDFIEATLTGIAAQ
Rv1194c|M.tuberculosis_H37Rv RTGEHIGWRFWMGIAFELTSDPQELRELLDVSARSVNDFIEATLTGIAAQ
MLBr_01052|M.leprae_Br4923 RVGQYTAWRRWMEIAFTLTSDPQELREILNVSAQSINEYVAATLEAIATH
MAB_2657c|M.abscessus_ATCC_199 RAVQRVGWKWWLAACFQVTDDKEQLCELIEVTSNSLTTFVDDSIAELAEH
MSMEG_0579|M.smegmatis_MC2_155 ATAVITALAQALDGAACLMSPDGRALTGPVGPRRGEFPFDDAAADVRRLQ
: :
Mflv_4621|M.gilvum_PYR-GCK YQTERAEWDERRRSLRAQAIRDILNGRD------VDLTEASSAMRYFLGA
TH_3143|M.thermoresistible__bu YDTERERWLEHRNNIRAVRVREILDSDEP-----IDIDTASAALGYPLRG
MMAR_4242|M.marinum_M VQLEHDELTRGNHADRLEVVGHLLEGAP------ISRERAETRLGYSLIR
MUL_0944|M.ulcerans_Agy99 VQLEHDELTRGNHADRLEVVGHLLEGAP------ISRERAETRLGYSLIR
Mb1226c|M.bovis_AF2122/97 VQSEHDELTRSTHAERLEVVGLILDGAP------ISPERAEAKLGYPLSR
Rv1194c|M.tuberculosis_H37Rv VQSEHDELTRSTHAERLEVVGLILDGAP------ISPERAEAKLGYPLSR
MLBr_01052|M.leprae_Br4923 MQLERDELTRSTHAERLEVVDLILEGAP------VTQERAEARLGYRLGL
MAB_2657c|M.abscessus_ATCC_199 VRRVREELAGGSQLQRYATVELLLQGAD------IAPARAEAQLGYALTG
MSMEG_0579|M.smegmatis_MC2_155 TQAGRSAATQSRPALSLSVQPIGLRGRPAAYLATMGPVRLSDAERDALTT
: * . : . *
Mflv_4621|M.gilvum_PYR-GCK THVALMVWLDRDAGADTDEFIAMERFMQHAVSATGAKQS-VYFSIDRLVG
TH_3143|M.thermoresistible__bu RHLALVLWMTR-SDLPGGELLRLERFARAVAEAFQLRNTPLFVAEDTVSG
MMAR_4242|M.marinum_M AHTAAIIWSDD----FDGDHSNLDRAADAFCHAVGSSQD-LTVVANAATR
MUL_0944|M.ulcerans_Agy99 AHTAAIIWSDD----FDGDHSNLDRAADAFCHAVGSSQD-LTVVANAATR
Mb1226c|M.bovis_AF2122/97 AHTAAIIWSDE----LDGDHSYLDRAADLFCHAVGSTRP-LTVVAGAASR
Rv1194c|M.tuberculosis_H37Rv AHTAAIIWSDE----LDGDHSYLDRAADLFCHAVGSTRP-LTVVAGAASR
MLBr_01052|M.leprae_Br4923 THTAAVIWSDD----LDGDHGYLDQAAEAFSHVVESTQQ-LIVVASAATR
MAB_2657c|M.abscessus_ATCC_199 SHIGAVVWVDS----EK-EIAALERASEQVMRACGADRR-LTVVAGTVAL
MSMEG_0579|M.smegmatis_MC2_155 SVAVLGLVDEQRRSRSTTRQHLHSRAIELLAGNDSRTAQLILEVDAPALV
: .: :
Mflv_4621|M.gilvum_PYR-GCK CAWMTV-HRPSDYLSQLRDFVRAQPD------------------------
TH_3143|M.thermoresistible__bu WAWLAINHVVTEPVRTIRELAETADN------------------------
MMAR_4242|M.marinum_M WVWLAEATNLD--IDTIEQAVDNAS-------------------------
MUL_0944|M.ulcerans_Agy99 WVWLAEATNLD--IDTIEQAVDNAS-------------------------
Mb1226c|M.bovis_AF2122/97 WAWVTDADGLD--IDTVQAAVDNAP-------------------------
Rv1194c|M.tuberculosis_H37Rv WAWVTDADGLD--IDTVQAAVDNAP-------------------------
MLBr_01052|M.leprae_Br4923 WVWLADALALD--VPEVQKALLNLS-------------------------
MAB_2657c|M.abscessus_ATCC_199 WLWIPAKTTPT--VAVLMDSLGRRS-------------------------
MSMEG_0579|M.smegmatis_MC2_155 IPERIRFLRATGGDSEITDAVTALERRGILAGTYADELCTVAVPERAEAA
:
Mflv_4621|M.gilvum_PYR-GCK GPRLSVGEPLPGIEGFRRTYRQAEQARVVAVAADGSSRHRIVAARDPGVA
TH_3143|M.thermoresistible__bu GVHVALGTVDDGLEGFRRSHRRARDARKVAAAS--AIPPRITAADDYGIS
MMAR_4242|M.marinum_M DARIAIGTKASGIEGFRRSHLEALTTQRTLARLK----SDQRVAFFSDVQ
MUL_0944|M.ulcerans_Agy99 DARIAIGTKASGIEGFRRSHLEALTTQRTLARLK----SDQRVAFFSDVQ
Mb1226c|M.bovis_AF2122/97 GARIAIGTTANGVEGFRRSHLEALITQRTLSRLR----STQRVAFFADVK
Rv1194c|M.tuberculosis_H37Rv GARIAIGTTANGVEGFRRSHLEALITQRTLSRLR----STQRVAFFADVK
MLBr_01052|M.leprae_Br4923 KARVAIGTSSAGIEGFRRSHLEALTAQRTLARLK----SHQQVAFFADVQ
MAB_2657c|M.abscessus_ATCC_199 GVRVALGRAATGMAGFRRTHMDAAAAQRLLARLG----SPLSVVRYEDVH
MSMEG_0579|M.smegmatis_MC2_155 GESMVDAGLQVGVGAAVPSDDGASGYRTAGLALAQTTPTAALVVWDRVVN
: . *: . : * : .. :
Mflv_4621|M.gilvum_PYR-GCK LASMLMTDDATLKEWIHDVLGPLAQNTASDQRLRDTLRVFLRAGSSFKAA
TH_3143|M.thermoresistible__bu VSALLTENLADTRRWVLDTLGPLASDTANDARLRETLLVFLHVGSSYTAA
MMAR_4242|M.marinum_M IVALITQNPQAADEFITSTLGELESAAP---ELQATLLMFINEQCNASRA
MUL_0944|M.ulcerans_Agy99 IVALITQNTQAANEFITSTLGELESAAP---ELQATLLMFINEQCNASRA
Mb1226c|M.bovis_AF2122/97 MVALISQNPDAASEFITSTLGDLESASP---DLQTALLTFINEQCNASRA
Rv1194c|M.tuberculosis_H37Rv MVALISQNPDAASEFITSTLGDLESASP---DLQTALLTFINEQCNASRA
MLBr_01052|M.leprae_Br4923 LVSLITQNPEDAKEFITSTLGDFESASP---ALQQTLLTFINEQCNASRA
MAB_2657c|M.abscessus_ATCC_199 LMDLLSADPASADQFVTDVLGEFQSASP---VLHQTVLTYVEEALNRTST
MSMEG_0579|M.smegmatis_MC2_155 DGPLGLIDPQRAAAFAESWLSGLDSEQL------ETLRCFLRHHGSRLKV
: : : . *. : . :: ::. . .
Mflv_4621|M.gilvum_PYR-GCK ANELQIHANTVKYRVNRALERRGRPIAAERLDVEVALLMCYWLGEVALNP
TH_3143|M.thermoresistible__bu AERLLLHPNSVRYRVNRAVERRARPIGEDRLEVELALLACRHFQQAVLQP
MMAR_4242|M.marinum_M AKRLYTHRNTLLRRIEAAQRLLPRPLAHTSVHVAVALEALQWRGDNIAKL
MUL_0944|M.ulcerans_Agy99 AKRLYTHRNTLLRRIEAAQRLLPRPLAHTSVHVAVALEALQWRGDNIAKL
Mb1226c|M.bovis_AF2122/97 AKRLHTHRNTFLRRLESAQRLLPRPLDHTSVHVAVALEALQWRGNKAHAL
Rv1194c|M.tuberculosis_H37Rv AKRLHTHRNTFLRRLESAQRLLPRPLDHTSVHVAVALEALQWRGNKAHAL
MLBr_01052|M.leprae_Br4923 AKRLFTHRNTLLRRIESAEKLLPRPLDHTSVHIAVALEALQWRGDQTNTS
MAB_2657c|M.abscessus_ATCC_199 AERLYTHRNTIDRRLARVDELLPKPFARNPIEVAAALTLLRVRAGR----
MSMEG_0579|M.smegmatis_MC2_155 AEELGLHRNTVRNRLDAIEALLPGRLDDPQTRVSAWIALQSLPPENRPVS
*:.* * *:. *: : : :
Mflv_4621|M.gilvum_PYR-GCK TQALGRS-----
TH_3143|M.thermoresistible__bu AD----------
MMAR_4242|M.marinum_M PTPTSQDDEVPA
MUL_0944|M.ulcerans_Agy99 PTPTSQDDEVPA
Mb1226c|M.bovis_AF2122/97 SSPGRRSNSVPA
Rv1194c|M.tuberculosis_H37Rv SSPGRRSNSVPA
MLBr_01052|M.leprae_Br4923 GPRAGRNDGVPA
MAB_2657c|M.abscessus_ATCC_199 ------------
MSMEG_0579|M.smegmatis_MC2_155 P-----------