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NFSILPPEINSARIFAGAGSGPMLQAAAAWDGLAAELSSAADSFGSVTSGLVGGSWQGPAAAAMTAAAAP YSAWLSVAAARAQSAAGQAKTVASTFEAAWAAMIHPVAVGQNRSQFVSLVRSNLFGFNAPAIAAVEAQYE QMWAQDVAAMSGYHAGVSASAAALAPWQTVLQNLPGLSGVNLGIGNIGNFNVGSGNFGSYNFGGGNSGPS STSGGIGNIGFGNYGNSNVGAGNGNAALGVPGSSYPGASSYNVGAGNIGQFNIGLGNFGSGNIGFGNGNL VTAVAGNPSASNVGAANIGSHNWGIGNIGINNIGLGNVGNNNIGIGLSGDNQIGIGGFNANGAGWNLGFG NDGSFNIGLGNTGNGNIGLANTGDGNIGIGLTGDNQIGFGGWNSGAGNTGLFNSGAGNSGFFNSGSDNWG LANTGSTNWGAVNSGSLNTGIGNTGSTNTGWWNAGSVNDGLFNAGNANLGLANSGNGNLGGFNSGGGTSA LFGHDIGFFNAGNHNVGMFNAGFANVGWANAGIGNTGAFNVGGNDANPVTGAGTIGQAGNTGFFNAGYAN TGLFNAGDSNTGLWNTGNVNTGVGGTGTHSGNSGFGNSGTGNSGFFNSGSYNSGLINSSAGGYSSGVGNS GGGGYNVGFFNSSAGGTDTGFFNYGDGGLHVGWLSSGDHVVGLASTGYYNTGLFNSGDHNTGVGNQGSNS SGFGNSGHYNSGGFNAGDYQSGFFGRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4218 | - | - | 100% (728) | PPE family protein |
| M. marinum M | MMAR_0926 | - | 0.0 | 68.67% (731) | PPE family protein |
| M. marinum M | MMAR_4554 | - | 0.0 | 52.80% (731) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3184c | PPE70 | 1e-168 | 48.84% (731) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 8e-34 | 28.75% (560) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv2356c | PPE40 | 1e-168 | 48.40% (721) | PPE family protein |
| M. leprae Br4923 | MLBr_01182 | - | 6e-31 | 42.33% (163) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-28 | 30.85% (603) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4704 | - | 1e-51 | 54.89% (184) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 6e-36 | 27.67% (571) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3569 | - | 2e-28 | 40.74% (162) | PUTATIVE PPE protein |
| M. ulcerans Agy99 | MUL_0965 | - | 1e-177 | 42.60% (892) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-34 | 27.65% (727) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4218|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------------MMFLAPPG
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4218|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---------------------------------------MVTFGGGATPT
Mvan_1264|M.vanbaalenii_PYR-1 GPGPISAAIQLTSTGSEATEP----------------WYVVSFGGSGAPT
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4218|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK PTSLGAA-------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 PNNLAAS-------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0965|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4218|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 ---------------------MN-----------------YSVLPPEINS
Rv2356c|M.tuberculosis_H37Rv --------------------MVN-----------------FSVLPPEINS
MUL_0965|M.ulcerans_Agy99 ---------------------MN-----------------FIMLPPEINS
MMAR_4218|M.marinum_M ---------------------MN-----------------FSILPPEINS
MAV_4704|M.avium_104 --------------------MTNPH---------------FAWLPPEVNS
Mflv_5091|M.gilvum_PYR-GCK --------------------AVDLSGTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 --------------------LVDLSGTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MLBr_01182|M.leprae_Br4923 --------------------MFD-----------------FAALSPETNS
MAB_4284c|M.abscessus_ATCC_199 ------------------MSIIDFILNLFR------DPVEAASYVADPEA
TH_3569|M.thermoresistible__bu --------------------MMTAP--------------IWMALPPEVHS
: .
Mb3184c|M.bovis_AF2122/97 LRMFTGAGSAPMLAASVAWDGLAAELAVAASSFGSVTSGLAG---QSWQG
Rv2356c|M.tuberculosis_H37Rv GRMFFGAGSGPMLAAAAAWDGLAAELGLAAESFGLVTSGLAGGSGQAWQG
MUL_0965|M.ulcerans_Agy99 ARIFAGAGVGPTLAAAAAWDALAADLASAAQSFAAITVGLVG---EAWQG
MMAR_4218|M.marinum_M ARIFAGAGSGPMLQAAAAWDGLAAELSSAADSFGSVTSGLVG---GSWQG
MAV_4704|M.avium_104 ALIYSGPGPGPLLAAAAAWDGLAEELASSAQSFSSVTSDLAS---GSWQG
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MLBr_01182|M.leprae_Br4923 TRMYLGPGSSPILTAAAAWVVLAKELTAAAQGLQSAVEALLT----TFEG
MAB_4284c|M.abscessus_ATCC_199 ALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNL
TH_3569|M.thermoresistible__bu ALLSSGPGPGSLLAAASAWHALSAEYASAAAELSSVLANVQAG---SWEG
. .
Mb3184c|M.bovis_AF2122/97 -AAAAMAAAAAPYAGWLAAAAARAAGASAQAKAVAS-----AFEAARAAT
Rv2356c|M.tuberculosis_H37Rv AAAAAMVVAAAPYAGWLAAAAARAGGAAVQAKAVAG-----AFEAARAAM
MUL_0965|M.ulcerans_Agy99 AAATAMAAAARPYASWLGTAAARAAVTAAQANAAAA-----VFEAAQAAT
MMAR_4218|M.marinum_M PAAAAMTAAAAPYSAWLSVAAARAQSAAGQAKTVAS-----TFEAAWAAM
MAV_4704|M.avium_104 ASSAAMMTVANQYVSWLSAAAAQAEEVSHQASAIAT-----AFEVALAAT
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
MLBr_01182|M.leprae_Br4923 ESAAALAERVTPYEKWLTQNAASAELTATQLTVAAN-----AYETAFTMT
MAB_4284c|M.abscessus_ATCC_199 QNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFAS--HNPIASGNQVMS
TH_3569|M.thermoresistible__bu PSAERYVAAHAPYLAWLTQQSANSAATAGRHETAAA-----AYSTALATM
.
Mb3184c|M.bovis_AF2122/97 VHPMLVAANRNAFVQLVLSNLFGQNAPAIAAAEAMY-----------EQM
Rv2356c|M.tuberculosis_H37Rv VDPVVVAANRSAFVQLVLSNVFGQNAPAIAAAEATY-----------EQM
MUL_0965|M.ulcerans_Agy99 AHPELVAANRNQLVSLVVSNLFGQNAPAIASTEAAY-----------DQL
MMAR_4218|M.marinum_M IHPVAVGQNRSQFVSLVRSNLFGFNAPAIAAVEAQY-----------EQM
MAV_4704|M.avium_104 VQPAVVAANRALVQALAATNWLGQNTPAIADIEAAY-----------EQM
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
MLBr_01182|M.leprae_Br4923 VPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKEAEY-----------TEM
MAB_4284c|M.abscessus_ATCC_199 PSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDGAV-------------A
TH_3569|M.thermoresistible__bu PTMAELTLNKTTHAVLVATNFLGINTIPIALNEADY-----------VRM
. . . .
Mb3184c|M.bovis_AF2122/97 WAADVAAMVGYHGGASAAAAALPSWQQALRGLPGLGQVASAISGGA----
Rv2356c|M.tuberculosis_H37Rv WAADVAAMVGYHGGASAAAAALAPWQQAVPGLSGL------LGGAA----
MUL_0965|M.ulcerans_Agy99 WAQDVAAMAGYHSGASAVAAQLAPWQQALRTLQNRVAGATTALPPP----
MMAR_4218|M.marinum_M WAQDVAAMSGYHAGVSASAAALAPWQTVLQNLPGLSGVNLGIGNIGNFNV
MAV_4704|M.avium_104 WASDVAAMFGYHADASAAVAKLPPWNEVLQ--------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
MLBr_01182|M.leprae_Br4923 WIQDAAAMTSYQASVLEAVGATKAFTAPPLG-------------------
MAB_4284c|M.abscessus_ATCC_199 VGGSNSGPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDYT
TH_3569|M.thermoresistible__bu WIQAATSMSTYQAVAGTAVMSAPASSPAPLLLAP----------------
.
Mb3184c|M.bovis_AF2122/97 ASMFAAPAAATAAVTPPALNTG--------LGNIGSWNLGGGN-------
Rv2356c|M.tuberculosis_H37Rv NAPAAAAQGAAQGLAELTLNLG--------VGNIGSLNLGSGN-------
MUL_0965|M.ulcerans_Agy99 GPAAAAALPGAAAVGFPVLHIGNIGFANLSVGNIGDYNLGSGN-------
MMAR_4218|M.marinum_M GSGNFGSYNFGGGNSGPSSTSGGIG--NIGFGNYGNSNVGAGNGNAALGV
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAG------
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATG------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 NVSGHGSADIDKSVTVVDDHSQ-----------RNTTNINDSFN------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 -------VGLLNLGSGNFGSLNLG--------------------GGNTGN
Rv2356c|M.tuberculosis_H37Rv -------IGGTNVGSGNVGGTNLG--------------------SGNYGS
MUL_0965|M.ulcerans_Agy99 -------TGSFNLGSGNIGDASLG--------------------SGNAGD
MMAR_4218|M.marinum_M PGSSYPGASSYNVGAGNIGQFNIG--------------------LGNFGS
MAV_4704|M.avium_104 -----------NLGFSNASTAVTR--------------------PAGSGA
Mflv_5091|M.gilvum_PYR-GCK ------GAGGLGETGTTGGAGGVG--------------------GQGTAG
Mvan_1264|M.vanbaalenii_PYR-1 ------QAGTAGETGVTGGVGGIG--------------------GQGTEG
MSMEG_0868|M.smegmatis_MC2_155 ------GDGGHSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDG
MLBr_01182|M.leprae_Br4923 -------VNEVGLAQEVVEEVVEEV-------------------VEEVVE
MAB_4284c|M.abscessus_ATCC_199 ------TDRSTNIGSGNTTNTEIGSHN-----------------QANIGT
TH_3569|M.thermoresistible__bu -------------GVSEAADAMAT--------------------TQQIGS
Mb3184c|M.bovis_AF2122/97 ANLGGGNWGFAN---------LGSGNIG----------------------
Rv2356c|M.tuberculosis_H37Rv LNWGSGNTGTGN---------AGSGNTG----------------------
MUL_0965|M.ulcerans_Agy99 SNVGFGNFGSNN---------VGIGNNGNNNIGIGLNGDDLIGIGALNSG
MMAR_4218|M.marinum_M GNIGFGNGNLVT---------AVAGNPS----------------------
MAV_4704|M.avium_104 VARGYTSRIAGF---------LAPRAPQ----------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGVGGIGGAG----------STGAVGG---------------------
Mvan_1264|M.vanbaalenii_PYR-1 GTGGVGGVGGVG----------ATGGAGG---------------------
MSMEG_0868|M.smegmatis_MC2_155 GTGGAGGMGEIYSGADGEATGISAGGDGGSATGADS--------------
MLBr_01182|M.leprae_Br4923 AEQAISQAALDQ--------------------------------------
MAB_4284c|M.abscessus_ATCC_199 STSAGGSAAVGG----------NAGLAGN---------------------
TH_3569|M.thermoresistible__bu QATAADSGTALN--------------------------------------
.
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0965|M.ulcerans_Agy99 AGNLGFGNSGTNNIGFFNSGDNNIGFFNSGSGNFGFENAGDINTGFWNGR
MMAR_4218|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------------VGGKG----IQGGQG-------------LQGGK
Mvan_1264|M.vanbaalenii_PYR-1 -----------------VGGKG----IQGGQG-------------LQGGQ
MSMEG_0868|M.smegmatis_MC2_155 -----------------LGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGK
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------------AGL
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 NTNFGNGNQGNLNFGSGNL-------------------LGNGNFGFGNA-
Rv2356c|M.tuberculosis_H37Rv DYNPGSGNFGSGNFGSGN--------------------IGSLNVGSGN--
MUL_0965|M.ulcerans_Agy99 DTNTGFGNSGLSNFGFGNSGVN----------NVGAGNGGSSNVGLGNAG
MMAR_4218|M.marinum_M ASNVGAANIGSHNWGIGN--------------------IGINNIGLGN--
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGDGGAGGKGGDADSMGS------------------AGATGGKGGNGGNG
Mvan_1264|M.vanbaalenii_PYR-1 GGDGGTGGTGGDATSMGE------------------AGATGGKGGNGGNG
MSMEG_0868|M.smegmatis_MC2_155 ASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAVGGNGGFT
MLBr_01182|M.leprae_Br4923 AVNEGMEATVVPQVDQQVN-------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGNAGLAGNAGLAGNAGLAG-------------------NAGLAGNAG--
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0965|M.ulcerans_Agy99 LLNTGSFNSGKFNTGDFNSGSMNTGYFNSSGHNTGLGNSGFTNTGFFNSG
MMAR_4218|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GRGGLFG---------------KGGNAGNGAD------------------
Mvan_1264|M.vanbaalenii_PYR-1 GRGSLFG---------------RGGNAGNGGN------------------
MSMEG_0868|M.smegmatis_MC2_155 NIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGPAGTTIDK
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0965|M.ulcerans_Agy99 DLNTGMGSPEDQSVANSGFRNAGSGNSGFNNTGSFSSGFFNSTNSNSEFL
MMAR_4218|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----GGTGGAGGAGGTGG-TGGAGGTGG-----------------TGGTG
Mvan_1264|M.vanbaalenii_PYR-1 ----GGTGGNGGNGGTGG-TGGNGGTGG-----------------TGGTG
MSMEG_0868|M.smegmatis_MC2_155 GKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQTDTGGNG
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 ------------FGDGNLGSGNVGSTNLGSG----NFGSFNVGSGNMG--
Rv2356c|M.tuberculosis_H37Rv ------------FGTLNLANGNNGDVNFGGG----NTGDFNFGGGNNG--
MUL_0965|M.ulcerans_Agy99 NAGGTVNSGINNSGNTNAGIGNLGDDNFGLF----NNGTFNTGAGNSSGG
MMAR_4218|M.marinum_M ------------VGNNNIGIGLSGDNQIGIGGFNANGAGWNLGFGNDG--
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGG
MLBr_01182|M.leprae_Br4923 ---------------VDVATPQTAVPDSSSAAAPQLWGGFAQHLSPIN--
MAB_4284c|M.abscessus_ATCC_199 -------------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG-
TH_3569|M.thermoresistible__bu -----------------LSDLIANLLQYYQDYLDQLFGPIVDFLRDP---
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv2356c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0965|M.ulcerans_Agy99 AVFPYTSGLFNSGNGSSGVFNAGDEQSGFFGTSGLVLTGTDGLAATTTSG
MMAR_4218|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGGTG---------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 DGGTG---------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 NGGTGGVGL-----------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 -------MSNIGFGNLG-----------NNNLGFGNNG-----------N
Rv2356c|M.tuberculosis_H37Rv -------TLNFGFGNTG-----------SGNFGFGNTG-----------N
MUL_0965|M.ulcerans_Agy99 LPALDLPAPNLGIGNAG-----------VGNLGLGNIG-----------D
MMAR_4218|M.marinum_M -------SFNIGLGNTG-----------NGNIGLANTG-----------D
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --GDGGTGGTGGTGGTG---------GTGGTGGTGGAG-----------D
Mvan_1264|M.vanbaalenii_PYR-1 --GTGGTGGTGGTGGTG---------GTGGTGGTGGAG-----------D
MSMEG_0868|M.smegmatis_MC2_155 --GNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGT
MLBr_01182|M.leprae_Br4923 ------DTLSMINNHAG-----------MANAGLSLVN------------
MAB_4284c|M.abscessus_ATCC_199 ------LAGNAGLAGNAG---------LAGNAGLAGNAG---------LA
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 NNIGFGLTGDNLVG---IGALNSGIG-----------------NMGFGNS
Rv2356c|M.tuberculosis_H37Rv NNIGIGLTGDGQIG---IGGLNSGTG-----------------NIGFGNS
MUL_0965|M.ulcerans_Agy99 YNLGSGNTGDANFGSGNIGALNLGSGNH------------GDANLGFGNT
MMAR_4218|M.marinum_M GNIGIGLTGDNQIG---FGGWNSGAGNTGL-------FNSGAGNSGFFNS
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGTGG----TGGQGGQGGQGG-----------------TGGTGGQ
Mvan_1264|M.vanbaalenii_PYR-1 GLGGTGGTGG----TGGFGGQGGQGG-----------------TGGTGGQ
MSMEG_0868|M.smegmatis_MC2_155 ATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGN
MLBr_01182|M.leprae_Br4923 ---------------------------------------------GMGSA
MAB_4284c|M.abscessus_ATCC_199 GNAGLAGNAG-------LAGNAGLAG-----------------NAGLAGN
TH_3569|M.thermoresistible__bu ----------------------------------------------IGNL
Mb3184c|M.bovis_AF2122/97 GNNNIGFFNSG------------------------NGNVGFFNSGDGNTG
Rv2356c|M.tuberculosis_H37Rv GNNNIGFFNSG------------------------DGNIGFFNSGDGNTG
MUL_0965|M.ulcerans_Agy99 GDNNIGLFNSG------------------------DNNVGFFNSGGANFG
MMAR_4218|M.marinum_M GSDNWGLANTG------------------------STNWGAVNSGSLNTG
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GG-LGGGGGTG-----------------------GQGGTGGTGGQGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GG-LGGVGGTG-----------------------GTGGTGGTGGQGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GGTLGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGG
MLBr_01182|M.leprae_Br4923 MKSLAPTTTKA-----------------------AESAFKAMGSAVQSTG
MAB_4284c|M.abscessus_ATCC_199 AAVAGNAAVAG------------------------NAAVAGNAAVGGVLN
TH_3569|M.thermoresistible__bu FQLIDDFLTNP------------------------AGALVTWWPLLFAVA
Mb3184c|M.bovis_AF2122/97 FGNAGDVN---------TGFWNGGPFNTGFGNGGNT--------------
Rv2356c|M.tuberculosis_H37Rv FGNAGNIN---------TGFWNAGNLNTGFGSAGNG--------------
MUL_0965|M.ulcerans_Agy99 LANSGDTN---------TGLWNAGSTNTGFGNAGSA--------------
MMAR_4218|M.marinum_M IGNTGSTN---------TGWWNAGSVNDGLFNAGNANLGLANSGNGNLGG
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TGGTGGTG--------GTGGAGGDGGLGGLGGFGGS--------------
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTG--------GTGGAGGDGGLGGLGGFGGV--------------
MSMEG_0868|M.smegmatis_MC2_155 QGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD--------------
MLBr_01182|M.leprae_Br4923 RGLLGSSS--------------GGHVTAQLGRAASIG-------------
MAB_4284c|M.abscessus_ATCC_199 TGVSGAIG---------GSSHVGGAINESLGGSGSVG-------------
TH_3569|M.thermoresistible__bu YQVFTNLVG-----------------------------------------
Mb3184c|M.bovis_AF2122/97 -------------NFGFGNAGFQNMGHGNAGGVNVGSGNAGLANTGDFNS
Rv2356c|M.tuberculosis_H37Rv -------------NVGIFDGGNSNSGSFNVGFQNTGFGNSGAGNTGFFNA
MUL_0965|M.ulcerans_Agy99 -------------DFGFGNAGDRNMGFGNAGAANMGAGNSGSYNTGSFNS
MMAR_4218|M.marinum_M FNSGGGTSALFGHDIGFFNAGNHNVGMFNAGFANVGWANAGIGNTGAFNV
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG-
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG-
MSMEG_0868|M.smegmatis_MC2_155 -----------GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGP
MLBr_01182|M.leprae_Br4923 -------------SLRVPQTWTTASQPVTAATRALSPARVAVATE-----
MAB_4284c|M.abscessus_ATCC_199 ------------GSTAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGG-
TH_3569|M.thermoresistible__bu -----------------WPTWAMILASPVLIPLAITLGVAG---------
Mb3184c|M.bovis_AF2122/97 GGVVS---------GIGGNTGSFNSGNLNTGFGNAG-------DLNTGLF
Rv2356c|M.tuberculosis_H37Rv G---------------DSNTGFANAGNVNTGFFNGG-------DINTGGF
MUL_0965|M.ulcerans_Agy99 G---------------TLNTGDFNGGDHNTGWGNSG-------NTNTGGI
MMAR_4218|M.marinum_M GGNDANPVTGAGTIGQAGNTGFFNAGYANTGLFNAG-------DSNTGLW
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-A
Mvan_1264|M.vanbaalenii_PYR-1 ---GSGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-A
MSMEG_0868|M.smegmatis_MC2_155 SWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVA
MLBr_01182|M.leprae_Br4923 ----------------SESAPLLGGGLPMAPMVPGG-------GSGTGGV
MAB_4284c|M.abscessus_ATCC_199 ----------------SGSVGGSTAVGGGAHTGVGG-------GVSTGVG
TH_3569|M.thermoresistible__bu --------------------LVMIADQAQPPAEEAAP------EEDVAAP
Mb3184c|M.bovis_AF2122/97 NSGDVNTGIGSTVDQPGSVSGFG------------NTGTSVSGFNNSGNL
Rv2356c|M.tuberculosis_H37Rv NGGNVNTGFGSALTQAGANSGFG------------NLGTGNSGWGNSD--
MUL_0965|M.ulcerans_Agy99 NSGDLNTGFGSSADQAVTNSGFG------------NNGSGNSGFNNTGDT
MMAR_4218|M.marinum_M NTGNVNTGVGGTGTHSG-NSGFG------------NSGTGNSGFFNSGSY
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NG
Mvan_1264|M.vanbaalenii_PYR-1 TGASGAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NG
MSMEG_0868|M.smegmatis_MC2_155 TGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNG
MLBr_01182|M.leprae_Br4923 NTALRLQPRAFVMPRNPAAG------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGSHVGGGISESLGGSGSVGGST-----------AVGGGAHTGVGGGVNT
TH_3569|M.thermoresistible__bu VRAEPQNPLPLTXXX-----------------------------------
Mb3184c|M.bovis_AF2122/97 TSGFGNMN----------------------SNVFDSTSGFQNIG--DANV
Rv2356c|M.tuberculosis_H37Rv PSGTGNSGF---------------------FNTGNGNSGFSNAG--PAML
MUL_0965|M.ulcerans_Agy99 NSGFHNANT---------------------SALFSGHSGLLNAGG-SQSV
MMAR_4218|M.marinum_M NSGLINSSAGGYSSGVGNSGGGGYNVGFFNSSAGGTDTGFFNYGDGGLHV
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ANGSQGAAGKAGATGTTGATG---------AAGEDGDAGSGGSG-INGGA
Mvan_1264|M.vanbaalenii_PYR-1 ANGSQGAAGKAGATGTTGATG---------AAGDAGDPGSEAVD-INGGA
MSMEG_0868|M.smegmatis_MC2_155 GNGGKGADGWVQAYDPAGPVGSKI-ANSSAVAGNGGDGGVNGTGGASGGD
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GVGVGSHVGGGISESLGGSGSVGG------STAVGGGAHTSAINDALGGS
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 G------------------FFNSGNSNEGFFNTGMFNNGIYNSGVASTGI
Rv2356c|M.tuberculosis_H37Rv P------------------GFNSG-----FANIGSFNAGIANSGNNLAGI
MUL_0965|M.ulcerans_Agy99 G------------------INNTG-----SFNTVLFNTGFRTAGIANSAT
MMAR_4218|M.marinum_M G------------------WLSSGDHVVGLASTGYYNTGLFNSGDHNTGV
MAV_4704|M.avium_104 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGAGG-----------AGGEGGEGGDGGKGGAGAE--------GGAGGGG
Mvan_1264|M.vanbaalenii_PYR-1 GGAGG-----------AGGEGGEGGAGGAGGDGSE--------GGAGGSG
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNG
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GSVGG-------------STAVGGGAHTSAINESMNSSINASHSSSMNES
TH_3569|M.thermoresistible__bu --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 ANSGNASSGVANSGDNSSGAFNQGDNQAGFFGQP-----
Rv2356c|M.tuberculosis_H37Rv SNSGDDSSGAVNSGSQNSGAFNAGVGLSGFFR-------
MUL_0965|M.ulcerans_Agy99 NGLLTATSGVANSGNNSSGGFNANPDQSGFFN-------
MMAR_4218|M.marinum_M GNQGSNSSGFGNSGHYNSGGFNAGDYQSGFFGRS-----
MAV_4704|M.avium_104 ---------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
MLBr_01182|M.leprae_Br4923 ---------------------------------------
MAB_4284c|M.abscessus_ATCC_199 FGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH
TH_3569|M.thermoresistible__bu ---------------------------------------