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MVSTLGTAFESRGTRCAAWFTRPAGPGPYPLVVLAHGLGANHTMALARYERHFAAAGIATLAFDYRNLGA SDGTPRQRLSLRRHRQDIAAALEFARSLPDVDASRVALWGTSLGAMHVLLIAARRRDLCAVVVQCPIVDG PATLRRLGLAATLRAGPAIVEDALRCAAGLRRRYIPIVGPPGSLAAVTAAGALQGWRSTVEPGGSFDNRI AASNLLGIGVTSTKRAARQISAPLLVCVSRRETLMDPRHAEVVAGRAPRGIARHYDGDHFEIYHRPLVDS LLADQTAFLREHLHVEDT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3680 | - | - | 100% (298) | hypothetical protein MMAR_3680 |
| M. marinum M | MMAR_0385 | - | 3e-51 | 40.43% (282) | hypothetical protein MMAR_0385 |
| M. marinum M | MMAR_1669 | - | 7e-05 | 33.07% (127) | lysophospholipase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2330c | - | 5e-08 | 29.84% (124) | hypothetical protein Mb2330c |
| M. gilvum PYR-GCK | Mflv_3976 | - | 4e-43 | 38.89% (288) | dienelactone hydrolase |
| M. tuberculosis H37Rv | Rv2307c | - | 5e-08 | 29.84% (124) | hypothetical protein Rv2307c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2608 | - | 4e-42 | 37.29% (295) | putative hydrolase, alpha/beta fold |
| M. avium 104 | MAV_2688 | - | 2e-05 | 31.82% (66) | alpha/beta hydrolase |
| M. smegmatis MC2 155 | MSMEG_4450 | - | 4e-45 | 36.70% (297) | alpha/beta hydrolase |
| M. thermoresistible (build 8) | TH_2570 | - | 2e-50 | 41.20% (284) | PUTATIVE alpha/beta hydrolase fold |
| M. ulcerans Agy99 | MUL_1035 | - | 4e-50 | 40.07% (287) | hypothetical protein MUL_1035 |
| M. vanbaalenii PYR-1 | Mvan_1417 | - | 4e-40 | 35.31% (303) | peptidase S15 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2688|M.avium_104 --------------------------------------------------
MUL_1035|M.ulcerans_Agy99 -----MTQRQDVRFPCGEALISAWLYRPAGADPARPVPMLVMAHGLGAVR
MSMEG_4450|M.smegmatis_MC2_155 MAQPLSYTRDDVTFMSDGTSCAAWLYRPDGVNNP---PIVVLAHGFAAFR
Mflv_3976|M.gilvum_PYR-GCK ---MPTRD--DVRIPAHGDEIAAYVYRPPAGVG--ATACVVMAHGFTGTR
TH_2570|M.thermoresistible__bu ---MATTDRRDLRIPAHGEQLAAYFY-PPAGAGP-TTPCIVMAHGFTATR
MAB_2608|M.abscessus_ATCC_1997 ------MNRQSIRFNSHGIDCEAWLYRAQTVEDT--APIVVMAHGVGGTK
MMAR_3680|M.marinum_M -----MVSTLGTAFESRGTRCAAWFTRPAGPGPY---PLVVLAHGLGANH
Mvan_1417|M.vanbaalenii_PYR-1 --MGVGFTTRQVSFSSGGSRIAAELYLPAGPGPY---PAVVFAHGFSGTM
Mb2330c|M.bovis_AF2122/97 ---MSLKRCRALPVVAIVALVASGVITFIWSQQR--RLIYFPSAGPVPSA
Rv2307c|M.tuberculosis_H37Rv ---MSLKRCRALPVVAIVALVASGVIMFIWSQQR--RLIYFPSAGPVPSA
MAV_2688|M.avium_104 --------------------------------------------------
MUL_1035|M.ulcerans_Agy99 TMRLDAYAQRFSAAGYACLVFDYRNFGDSEGQPRQLLDIRMQLQDWAAAV
MSMEG_4450|M.smegmatis_MC2_155 ELRLDAYAARFAQAGYAALVFDYRHWGASDGQPRRILDIPKQQTDWRAAI
Mflv_3976|M.gilvum_PYR-GCK DDGLPDYAEAFRDAGYVVVLFDYRHFGASSGQPRQLLDMARQREDFHTVI
TH_2570|M.thermoresistible__bu DDGLPAYAEAFHAAGYAVVLFDYRHFGASTGEPRQLLDITRQHDDYRAVV
MAB_2608|M.abscessus_ATCC_1997 DSGLEPFAVRLAEAGMHALAFDYRGFGASDGFPRQHVSFTHQIGDYHAAV
MMAR_3680|M.marinum_M TMALARYERHFAAAGIATLAFDYRNLGASDGTPRQRLSLRRHRQDIAAAL
Mvan_1417|M.vanbaalenii_PYR-1 DWILPDFASVFAAGGLAVLLFDYRHFGSSEGQPRQLVDTGCQLEDIRAAL
Mb2330c|M.bovis_AF2122/97 SSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRA
Rv2307c|M.tuberculosis_H37Rv SSVLPAGRDVVVETQDGMRLGGWYFPHTSGGSGPAVLVCNGNAGDRSMRA
MAV_2688|M.avium_104 --------------------------------------------------
MUL_1035|M.ulcerans_Agy99 AYARTCDGVDQARIGLWGTSFGGGHVIATAARLPGIAAVVAQCPFTDGIA
MSMEG_4450|M.smegmatis_MC2_155 AYARSLDNVDTTRLVGWGSSFGGGHVLTLAARDHEFAAAIVQVPHVSGPA
Mflv_3976|M.gilvum_PYR-GCK EWARRLDGVDPNRIVAWGSSFSGGHVLAVAAEDPRLAAVIAQAPFTDALA
TH_2570|M.thermoresistible__bu AWARTQPGVDPDRIVLWGSSFSGGHVLVVAADDPRIAAVISQAPFTDAVP
MAB_2608|M.abscessus_ATCC_1997 NMARRLPGVDPTRIVLWGVSLAGGHVMAVAGARNDVAAVIALTPLVDGIA
MMAR_3680|M.marinum_M EFARSLPDVDASRVALWGTSLGAMHVLLIAARRRDLCAVVVQCPIVDGPA
Mvan_1417|M.vanbaalenii_PYR-1 AYARAHEAIDARRIGLWGTSLGGSHVINVASADPRIAAVVATVPALDMYV
Mb2330c|M.bovis_AF2122/97 ELAVALHGLGLSVLLFDYRGYGG------NPGRPSEQGLAADARAAQEWL
Rv2307c|M.tuberculosis_H37Rv ELAVALHGLGLSVLLFDYRGYGG------NPGRPSEQGLAADARAAQEWL
MAV_2688|M.avium_104 --------------------------------------------------
MUL_1035|M.ulcerans_Agy99 SVL------------AIAPTTAIRVTARSMRDLIGSRLGRPPVMIPTAGK
MSMEG_4450|M.smegmatis_MC2_155 SAF------------SQSPKLVARLIAAGLRDQIGAWFGGAPHRVTSIGR
Mflv_3976|M.gilvum_PYR-GCK TLR------------NAPLRNIPPMVVAALRDQLGAWRNRPPRMLAAVGP
TH_2570|M.thermoresistible__bu TLR------------KVPPATIARLAVAGLRDQIGSWRGRPPRTASAVGA
MAB_2608|M.abscessus_ATCC_1997 AAR------------SAMTEHSAGTLLRSAVTGLRSRLGRQQRTIPIVGR
MMAR_3680|M.marinum_M TLR------------RLGLAATLRAGPAIVEDALRCAAGLRRRYIPIVGP
Mvan_1417|M.vanbaalenii_PYR-1 GLRGRHRPATFRPGPARTVIATLRLVGAAALDAIRGRCGLRPYYLPVYGP
Mb2330c|M.bovis_AF2122/97 SGQ----------------SDVDPARIAYFGESLGAAVAVG---LAVQRP
Rv2307c|M.tuberculosis_H37Rv SGQ----------------SDVDPARIAYFGESLGAAVAVG---LAVQRP
MAV_2688|M.avium_104 --------------------------------------------------
MUL_1035|M.ulcerans_Agy99 PGEVALMTAPDAYPGYLGLMP--------QGTQVPNEVAARIGIKVLGYR
MSMEG_4450|M.smegmatis_MC2_155 PGEFAMMTSPGAYELVEEMAGGEAAEHMRAQLEAENDVAARIALRVPLYS
Mflv_3976|M.gilvum_PYR-GCK PGDLAALTSPDAEPGFGAILG--------PESLWRNEFAARLMLRFAFER
TH_2570|M.thermoresistible__bu PGAVAAMTTPDAEPGFRAIVE--------PDSLWRNEFAARLMLRFPFYR
MAB_2608|M.abscessus_ATCC_1997 AGELAALTSDGYYEAHLAIAG----------PAWRNEIDATVGTQLVSYR
MMAR_3680|M.marinum_M PGSLAAVTAAGALQGWRSTVE--------PGGSFDNRIAASNLLGIGVTS
Mvan_1417|M.vanbaalenii_PYR-1 LG-HAVFSDPALAERFRHVES--------NSPTWRNEVTPRFLFHAPRYR
Mb2330c|M.bovis_AF2122/97 PAALVLRSPFTSLAEVGAVHY---------------PWLPLRRLLLDHYP
Rv2307c|M.tuberculosis_H37Rv PAALVLRSPFTSLAEVGAVHY---------------PWLPLRRLLLDHYP
MAV_2688|M.avium_104 -------MSCPILFAICENDTVAPAKATQKYAAQAPRGEIK----LYDAG
MUL_1035|M.ulcerans_Agy99 PGRSARKIACPILFCVCETDSVAPAGPTLRYAARAPRGEVSGEVIRYPEG
MSMEG_4450|M.smegmatis_MC2_155 PGRHAAKITAPTLVQLATKDDVTPYAKARKIVARIPNGEVR----SYDIT
Mflv_3976|M.gilvum_PYR-GCK PGRKAATLQMPVLFCVCDDDVVTPPGPTIEAARRAPCGELR----RYPYG
TH_2570|M.thermoresistible__bu PVRVAGRINAPLLVCVCDDDAVTPPEPAIEAARRAPRGQLR----RYPYG
MAB_2608|M.abscessus_ATCC_1997 PTRCASRIGCPILVQIADFDRAAPPHAAAKAAFKA-RAEVR----HYPCD
MMAR_3680|M.marinum_M TKRAARQISAPLLVCVSRRETLMDPRHAEVVAGRAPRGIAR----HYDGD
Mvan_1417|M.vanbaalenii_PYR-1 DG-TVERIRCPVLVTLARDDAEVSSPYVRRKLGHAADVEIM----EYPVA
Mb2330c|M.bovis_AF2122/97 SIERIASVHAPVLVIAGGSDDIVPATLSEWLVAAAAEPKRYVVVPGVGHN
Rv2307c|M.tuberculosis_H37Rv SIERIASVHAPVLVIAGGSDDIVPATLSERLVAAAAEPKRYVVVPGVGHN
: * *. :
MAV_2688|M.avium_104 HFDIYVGADF-ERNVTDQLNFLSRHVPVS------------
MUL_1035|M.ulcerans_Agy99 HFAIYLGDAF-EHVVADQLGFLDKHLKPAGQP---------
MSMEG_4450|M.smegmatis_MC2_155 HFEPYVDPHF-EQIVTDQIDFLNRHVGAGTR----------
Mflv_3976|M.gilvum_PYR-GCK HFDIYHDP----QVKADQLEFLHRALARGGR----------
TH_2570|M.thermoresistible__bu HFDIYHDP----QVKSDQLDFLRQVLGTG------------
MAB_2608|M.abscessus_ATCC_1997 HFGVYHGQECHELVIGHQISFLSRHLSIEAVSHTEALHG--
MMAR_3680|M.marinum_M HFEIYHRPLV-DSLLADQTAFLREHLHVEDT----------
Mvan_1417|M.vanbaalenii_PYR-1 HFDVYHGPVR-AEIARDQRDFLVRHLLRGPNRATNSSGCGR
Mb2330c|M.bovis_AF2122/97 DPELLDGR----VMLDAIRRFLTETAVLGQ-----------
Rv2307c|M.tuberculosis_H37Rv DPELLDGR----VMLDAIRRFLTETAVLGQ-----------
. ** .