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VDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGVDSPEGLWQMVAEGRDVMSDFP TDRGWDLADLFDPDPDTPHKSYASTGGFVDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGI DPTGLRGSATGVFAGLIVQGYGMFAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALH MAVQSLRSGECDLALAGGATVNATPTVFVEFSRHRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDA QRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQ ALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVLPATLHVDVPSPHVDWSA GAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVVSAKSGSA LGAQAARLAAHVRSHDELDVADVGWSLAGRSTFEHRAVVLGVDRDGLLAGLDELAGDEFGGASVIRGVAG AAGKTVFVFPGQGSQWIGMGIELLDTAPVFARHIESCGQAFAEFVDWSLLDVLRGAAGAPGLDRVDVVQP VLFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDAAKVVTLRSKLLVGLAGPGGMVSVAC GEQQARELLEPFGDRVSIAAINGPSAVVVSGEVAALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQ LTEVLAGIEPLSSRTAFFSSVTGSRLDTAELDAEYWYRNIRQTVQFDQAVRSACGHGYRTFIESSPHPAL IAGIEDTYRNCAADSGADPIVVPTLGREDGGLQRFLASAAAAFVAGVNVDWRGPLDGAGLVELPTYAFEK RRFWLSGEGVSVDASGLGLSAGGHALLGAVVELPESGGVVLTGRLALGAHGWLADHAVSGVVVFPGTGFV ELAIRAGDEVGCSVVNELTLRTPLVLPASGSVAVQVVVGAAADSAERSVSIYSRTDTDAGSVWVCHAEGT LGADSAQPAADLSAWPPAGAIAVDVADGYERLDARGYGYGPAFRGLTAMWARGEELFAEVRLPEAAGSTS GFGVHPALLDAALHTAVIANPDAELVLPFSWQGVSLHAAGAASVRVRIAPVGPSSVSVELADDLGLPVLS VKAMVARPVSEQQMRAVVSASGPDRLFEVVWTPMTVAATDAAPAYELFESVAAEGDPLSGTYQRTHQALA AVQSWLTEHDSGVLVVATRGAMALAGEDVTDLAGAAVWGLVRSAQTENPGRLVLVDSDAAVDAAAVATAL AVGEPQVVLRNGQPYTARVHASRAADGILVPPVDGPWRLGLSSAGTFENLQLEPVPNAGAPLGPGQVRVA MRAIAANFRDIMITLGMFTHDALIGGEGAGVVVEIGPEVTEFAVGDAVYGFFPDGSGTLVAGDVRLLLPK PADWSYAEAAAISAVFTTAYYAFVHLANVQPGQRVLVHAATGGVGMAAVQLARHLGLEVYATASKGKWDI LRAMGFDEDHISDSRSLEFEEKFREVTGGRGVDVVLDSLAGEFVDASLRLLGPGGVFLEMGKTDIRDPGV IAQEYPGVRYRAFDLFEPGRPRMHQYMLDLAGLFDAGVLRPLPVTAFDVRRAPAALRYLSQARHIGKVVM TMPADQGGALGGGTVLITGGTGMAGSALARHLVAHHGVAHLVLISRRGPAAPGATELVAELSAAGAQVEV VACDAADRPALAKVIAEIPAQRPLSAVVHAGGVLDDAVISSLTPERVDTVLRAKVDAAWNLHELTRDLDL SAFVMFSSMAGVVGSSGQANYAAANTFVDGLAAHRRAHGLPAISLGWGLWDQASDMTGGMDAADRARLGR EGVLALSSDEAMELFDTALIVNQAFLAPARIDLAALRAHAVAVPPMFSDLVSAPTRRQVDDALAAAKSKS ALAHRLHGLPEPEQHAVVLDLVRSHIATVLGTITPEAIDPDKAFQELGFDSLTAVEMRNRIKTVTGLSLS PTLIFDYPTPNGLANYIRAELAGAPQEVKHTPAVRVTGDDPIAIVGMSCRYPGGIESPDDLWDMLMARRD VLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFDPAFFGVGPSEALAMDPQQRMFLELSWEA LERAGIEPGGLRGSATGVFAGVMTQGYGMFAAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACS SSLVALHMAVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLSADGRCKAFAGAADGTGFSEGGGMLV VERLSDAQRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL GDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVLPATLHVDVPS PHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVV SAKSGSALGAQAARLAAHVRSHDELDVADVGWSLAGRSTFEHRAVVLGVDRDGLLAGLDELAGDEFGGAS VIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVIWGHDENLLNT TEFAQPALFAVEVALYRLLESWGVRPDFVMGHSVGELSAAHVAGVLSLENAAVLVAARGRLMQALPDGGA MIAVQATEQEVLPLLGAQVSIAAINGPASVVISGAQDAVSAVAEQLRADGRRVHRLAVSHAFHSPLMDPM IDEFATVAGELTVNAPTIGIISNLTGQLAGEDFGSAAYWKRHVRDAVRFADSIRFAQSAGAARFLEVGPS SGLTASIEEVLSDAAVTNPVATASALRKDRPEPVSLVSAVAGVFVAGTAVDWRAVVGQSNFVELPTYAFE RRRFWLSGDAVAADAAGLGLQAGEHALLGAVVELPASGGVVLTGRLSLAAQGWLADHAVGGVVIFPGAGF VELAIRAGDEVGCRVVDELTLAAPLVLPSGGSVAVQVVVGSPDDSGARAVSVYSRGDAGSDWVLHAEGSL GSGSPEPATDLSTWPPVGAVEVENADGYQQLAERGYGYGPAFRGLNAMWRRGDEVFAEVALPADAGVSVS GFGIHPVMLDAALHAVILASDGADDFGVPEGSVLVPFAWQGVTLHAAGASAVRARIAPAGPSAVSIELSD GLGLPVLSVASMLARPVTDQQLRAAVSGAGPDRLFGVDWTAQPSAELQPVPVRIWGAVESEGDDDPGASV VFESVPQAGEVVAGVYAATAAVLEVLRSWLSRDGAGQLVITTRGAVALPDEDVTDLAGSAVWGLVRSAQT EHPGRIVLVDTDAQLDEHAVAAVLAAGEPQVLWRNGEVYTARVHGSRAVAGLLVPPGDGPWRLGMSTAGT FENLRLEPIPDADAALQPGHVRVALSAMAANFRDVMIALGLYPDPDAAMGVEGAGVVVETASTDGRFAVG DRVVGLFPEGTGTIAITDHRLLVKIPAGWSDTAAATTSVVFATAFYALRDLASVQPGQRILVHAATGGVG MAAVQLARHWGLEVFATASKGKWDTLRAMGFDEDHIGDSRSLEFEDKFRAATGGRGMDVVLDSLAGEFVD ASLRLVAPGGVFLEMGKTDIREAAVVAQQHTGVRYRAFDLFEAGPDHIAQILAELAALFSEDALRPLPVT TFDVRRAPAALRYLSQARHVGKVVLTMPDAWAAGTVLITGGTGMAGSALARHVVAHHGVRQLVLVSRRGP DAPGAAELAEELSAFGAQVQVVACDAADRAALAKLIADIPVQHPLSAVIHTAGALDDAVVTSLTPERMET VLRAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQGNYAAANSFLDGLAVHRQAHGLPAISLGWGL WDQASNMTGGLAAVDFKRFARDGIVAMSSDEALGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMF VDLINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIATVLGNSSPDAIDPDRAFQEL GFDSLTAVEMRNRLKSATGLALSPTLIFDYPNSAALAGYMHRELVGASPQSDITAEAPGEAELQRVVASI PVKRLRQAGVLELLLALANETGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_3025 | pks12 | - | 100% (4187) | polyketide synthase, Pks12 |
M. marinum M | MMAR_3798 | - | 0.0 | 45.23% (3111) | type I modular polyketide synthase |
M. marinum M | MMAR_2471 | pks7 | 0.0 | 60.28% (2062) | polyketide synthase Pks7 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2074c | pks12 | 0.0 | 82.98% (4188) | polyketide synthase pks12 |
M. gilvum PYR-GCK | Mflv_0405 | - | 0.0 | 36.64% (2549) | beta-ketoacyl synthase |
M. tuberculosis H37Rv | Rv2048c | pks12 | 0.0 | 83.19% (4188) | polyketide synthase pks12 |
M. leprae Br4923 | MLBr_00135 | - | 0.0 | 58.20% (2079) | putative polyketide synthase |
M. abscessus ATCC 19977 | MAB_3148c | - | 0.0 | 34.08% (2142) | polyketide synthase Pks5 |
M. avium 104 | MAV_2450 | - | 0.0 | 80.27% (4206) | erythronolide synthase, modules 3 and 4 |
M. smegmatis MC2 155 | MSMEG_0408 | - | 0.0 | 36.41% (2538) | type I modular polyketide synthase |
M. thermoresistible (build 8) | TH_4621 | - | 0.0 | 35.54% (1854) | PUTATIVE mycocerosic acid synthase |
M. ulcerans Agy99 | MUL_2266 | pks12 | 0.0 | 99.21% (4191) | polyketide synthase, Pks12 |
M. vanbaalenii PYR-1 | Mvan_1003 | - | 0.0 | 37.18% (2528) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0405|M.gilvum_PYR-GCK -----------------------MGSAAHQGE-SAHRFAIVGYAGRFPG- MSMEG_0408|M.smegmatis_MC2_155 -----------------------MVSAEHPIE-PTPSFAIIGYAARFPG- Mvan_1003|M.vanbaalenii_PYR-1 ---------MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPG- MMAR_3025|M.marinum_M -MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG MUL_2266|M.ulcerans_Agy99 -MVDQLQHATEALRKALVQVERLKRTKRALLERSSEPIAIVGMSCRFPGG Mb2074c|M.bovis_AF2122/97 -MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG Rv2048c|M.tuberculosis_H37Rv -MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG MAV_2450|M.avium_104 MMVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK ARDAESFWELLADGRDAISEVPEDR-WDVEAFFDPDPSTPGKVVTRRAGF MSMEG_0408|M.smegmatis_MC2_155 AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAGF Mvan_1003|M.vanbaalenii_PYR-1 AADADEFWDVLRGGRDAISEVPQDR-WDADEFFDADPEAAGKMVTRRAGF MMAR_3025|M.marinum_M VDSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHKSYASTGGF MUL_2266|M.ulcerans_Agy99 VDSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHKSYASTGGF Mb2074c|M.bovis_AF2122/97 VDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGF Rv2048c|M.tuberculosis_H37Rv VDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGF MAV_2450|M.avium_104 VDSPEALWQMVAEGRDVISEFPTDRGWDLAALYDPDPDARHKCYVNTGGF MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK VDDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANT MSMEG_0408|M.smegmatis_MC2_155 VDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANS Mvan_1003|M.vanbaalenii_PYR-1 VEDVAGFDAPFFGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGT MMAR_3025|M.marinum_M VDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGS MUL_2266|M.ulcerans_Agy99 VDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGS Mb2074c|M.bovis_AF2122/97 VDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGS Rv2048c|M.tuberculosis_H37Rv VDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGS MAV_2450|M.avium_104 VDNVADFDPAFFGIAPSEALAMDPQHRMLLELSWEALERAGIDPSGLRGS MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK NTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQ MSMEG_0408|M.smegmatis_MC2_155 NTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQ Mvan_1003|M.vanbaalenii_PYR-1 RTGVFMGLSTHDYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQ MMAR_3025|M.marinum_M ATGVFAGLIVQGYG------MFAEEIEGYRLTGMTSSVASGRVAYVLGLE MUL_2266|M.ulcerans_Agy99 ATGVFAGLIVQGYG------MFAEEIEGYRLTGMTSSVASGRVAYVLGLE Mb2074c|M.bovis_AF2122/97 ATGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLE Rv2048c|M.tuberculosis_H37Rv ATGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLE MAV_2450|M.avium_104 ATGVFAGLIVQGYG------MLAEEIEGYRLTGMTSSVASGRVSYVLGLE MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK GPAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVILTPATMITFS MSMEG_0408|M.smegmatis_MC2_155 GPAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFS Mvan_1003|M.vanbaalenii_PYR-1 GPAVAVDTACSSSLVAVHQACQALRLAECDVALAGGVNVLLSPATMINFS MMAR_3025|M.marinum_M GPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFS MUL_2266|M.ulcerans_Agy99 GPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFS Mb2074c|M.bovis_AF2122/97 GPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFS Rv2048c|M.tuberculosis_H37Rv GPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFS MAV_2450|M.avium_104 GPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFS MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK NAHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIR MSMEG_0408|M.smegmatis_MC2_155 NAHMLAPDGRCKTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIR Mvan_1003|M.vanbaalenii_PYR-1 RARMLAPDGRCKTFDATADGYVRGEGCGVVVVKRLADAIRHGDRIRAVIR MMAR_3025|M.marinum_M RHRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDAQRLGHPVLALVR MUL_2266|M.ulcerans_Agy99 RHRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDAQRLGHPVLALVR Mb2074c|M.bovis_AF2122/97 RHRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVV Rv2048c|M.tuberculosis_H37Rv RHRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVV MAV_2450|M.avium_104 RHRGLAPDGRCKAYAGAADGVGWSEGGAMLVVERLSDARRLGHPVLAVVR MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK GSAINQDGASGGLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTS MSMEG_0408|M.smegmatis_MC2_155 GSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVGYLEAHGTGTS Mvan_1003|M.vanbaalenii_PYR-1 GSAVNQDGASGGLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTP MMAR_3025|M.marinum_M GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT MUL_2266|M.ulcerans_Agy99 GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT Mb2074c|M.bovis_AF2122/97 GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT Rv2048c|M.tuberculosis_H37Rv GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT MAV_2450|M.avium_104 GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK LGDPIEAQAAGAALGPGREPQ----RPLLIGSAKTNIGHLEAAAGIAGVI MSMEG_0408|M.smegmatis_MC2_155 LGDPIEAQAAGEVLGAGRAPE----EPLLIGSAKTNIGHLEAAAGIAGVI Mvan_1003|M.vanbaalenii_PYR-1 LGDPIEVQAAGAVLGVGREPD----RPLLIGSVKTNIGHLEAASGIAGLL MMAR_3025|M.marinum_M LGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVI MUL_2266|M.ulcerans_Agy99 LGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVI Mb2074c|M.bovis_AF2122/97 LGDPIEAQALLATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVI Rv2048c|M.tuberculosis_H37Rv LGDPIEAQALLATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVI MAV_2450|M.avium_104 LGDPIEAQALLATYGQDRGQP------LWLGSIKSNMGHTQAAAGVAGVI MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK KVVLSLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPR MSMEG_0408|M.smegmatis_MC2_155 KVVMALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR---NGKPR Mvan_1003|M.vanbaalenii_PYR-1 KVILSLEHQVLPKHLNFRSPSPHIPWNRLPVRIVDDPVPWTR---SGRSR MMAR_3025|M.marinum_M KMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVR MUL_2266|M.ulcerans_Agy99 KMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVR Mb2074c|M.bovis_AF2122/97 KMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTR Rv2048c|M.tuberculosis_H37Rv KMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTR MAV_2450|M.avium_104 KMVLAMRHELLPATLHVDEPSPHVDWSAGAVSLLTEAQPWP----GERPR MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK IAGVSSFGFAGTNAHVILEEAPLAAEPAQES--VDDGRFTLLPLSARTPA MSMEG_0408|M.smegmatis_MC2_155 IAGVSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPE Mvan_1003|M.vanbaalenii_PYR-1 VAGISSFGFSGTNAHVLVEEAPRADRAGAAPQPAAPGGFGMLPLSARTPD MMAR_3025|M.marinum_M RAGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVVS---AKSGS MUL_2266|M.ulcerans_Agy99 RAGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVVS---AKSGS Mb2074c|M.bovis_AF2122/97 RAGVSSFGISGTNAHVIIEAVPVVPRR-EAGWAGPVVPWVVS---AKSES Rv2048c|M.tuberculosis_H37Rv RAGVSSFGISGTNAHVIIEAVPVVPRR-EAGWAGPVVPWVVS---AKSES MAV_2450|M.avium_104 RAGVSSFGISGTNAHVIIEAVPAVEPAHADAPALPVLPWVVS---AKSAA MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK ALMAVADRYRDWLVANPDATLADLCFTAGTARSHLEHRAALVVNTREAAL MSMEG_0408|M.smegmatis_MC2_155 ALVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAI Mvan_1003|M.vanbaalenii_PYR-1 ALAATAHRLRTWLAANPDASWPDLCFTAAVGRSHLRHRAALVVDSRSSVE MMAR_3025|M.marinum_M ALGAQAARLAAHVRSHDELDVADVGWSLAG-RSTFEHRAVVLGVDRDGLL MUL_2266|M.ulcerans_Agy99 ALGAQAARLAAHVRSHDELDVADVGWSLAG-RSTFEHRAVVLGADRDGLL Mb2074c|M.bovis_AF2122/97 ALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLL Rv2048c|M.tuberculosis_H37Rv ALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLL MAV_2450|M.avium_104 ALRAQAARLAEYVRAQGELDIADVGWTLAG-RATFEHRAVVVGGDRDRLL MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK DLLGALADDRPA-PGLVRGESHDTPKTAWLFTGQGSQYPGMSRELFDTEP MSMEG_0408|M.smegmatis_MC2_155 ELLGALADDRPA-PGLVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEP Mvan_1003|M.vanbaalenii_PYR-1 ELLGALAEDRPG-PGLARGECGDPPKTAWLFTGQGSQYPGMGRELFDTEP MMAR_3025|M.marinum_M AGLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQWIGMGIELLDTAP MUL_2266|M.ulcerans_Agy99 AGLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQWIGMGIELLDTAP Mb2074c|M.bovis_AF2122/97 AGLDELAGDQLG-GSVVRGTATAAGKTVFVFPGQGSQWLGMGIELLDTAP Rv2048c|M.tuberculosis_H37Rv AGLDELAGDQLG-GSVVRGTATAAGKTVFVFPGQGSQWLGMGIELLDTAP MAV_2450|M.avium_104 AGLDELAADDPA-ASIIRGVATPAGKTVFVFPGQGSQWLGMATELLDTAP MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK LFAETLRECAAAVDGMLEKPLLDVIFDTDGVLDTDSNETLRHTSYAQPAL MSMEG_0408|M.smegmatis_MC2_155 VFAETVRKCAEAVADILEKPLLDVIFDAD-ELDGDTESPLRHTTYAQPAL Mvan_1003|M.vanbaalenii_PYR-1 VYREVMTRCAEAVADVLERPLLDVVFDAD------GGEALRHTSYAQPAL MMAR_3025|M.marinum_M VFARHIESCGQAFAEFVDWSLLDVLRGAA------GAPGLDRVDVVQPVL MUL_2266|M.ulcerans_Agy99 VFARHIESCGQAFAEFVDWSLLDVLRGAA------GAPGLDRIDVVQPVL Mb2074c|M.bovis_AF2122/97 AFAQQIDACAEAFAEFVDWSLVDVLRGAP------GAPGLDRVDVVQPVL Rv2048c|M.tuberculosis_H37Rv AFAQQIDACAEAFAEFVDWSLVDVLRGAP------GAPGLDRVDVVQPVL MAV_2450|M.avium_104 VFAQHIQACEEAFAEFVDWSLIDALRGAP------GAAGMDRVDVVQPAL MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK FAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLSLRDGARLMAER MSMEG_0408|M.smegmatis_MC2_155 FAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAER Mvan_1003|M.vanbaalenii_PYR-1 YAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAER MMAR_3025|M.marinum_M FAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDAAKVVTLR MUL_2266|M.ulcerans_Agy99 FAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDAAKVVTLR Mb2074c|M.bovis_AF2122/97 FAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLR Rv2048c|M.tuberculosis_H37Rv FAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLR MAV_2450|M.avium_104 FAVMVSLAELWKSVGVSPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLR MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK GRLFGSLPSGGRMAAVFAAAERVEALTDEY-PALSVAAYNG-ANTVLSGP MSMEG_0408|M.smegmatis_MC2_155 GRLFGSLPAGGRMAAVFTAPERAERLTDEY-PSLSVAAYNG-ANTVLSGP Mvan_1003|M.vanbaalenii_PYR-1 GRLFGSLPEGGRMAAVFAPADRVESCTVDS-PLLSVAAYNG-DNTVLSGP MMAR_3025|M.marinum_M SKLLVGLAGPGGMVSVACGEQQARELLEPFGDRVSIAAINGPSAVVVSGE MUL_2266|M.ulcerans_Agy99 SKLLVGLAGPGGMVSVACGEQQARELLEPFGDRVSIAAINGPSAVVVSGE Mb2074c|M.bovis_AF2122/97 SKLLAGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGE Rv2048c|M.tuberculosis_H37Rv SKLLAGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGE MAV_2450|M.avium_104 SKLLRSLAGPGGMLSIACSTERARELLAPYGNRVSIAAVNGRSAVVVSGE MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK ATDLERAVAGLVADGVRCDWLETSHAFHSALLDPILDDFESYARGITFTA MSMEG_0408|M.smegmatis_MC2_155 AKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYRE Mvan_1003|M.vanbaalenii_PYR-1 AGDLERAVAGFSAAGVRCDWLDTSHAFHSALLDPVLEEFESCADRFEFGT MMAR_3025|M.marinum_M VAALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQLTEVLAGIEPLS MUL_2266|M.ulcerans_Agy99 VAALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQLTEVLAGIEPLS Mb2074c|M.bovis_AF2122/97 VGALEELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAEALSGIEPRS Rv2048c|M.tuberculosis_H37Rv VGALEELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAEALSGIEPRS MAV_2450|M.avium_104 GAALDELAAFCADLALRTRRIDVDYASHSVEVEAIREDLAQALTGIEPRS MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK PQRILIDNRTGAALGRSVTLDAAYWRRHARQPVEFAKSVHTLADMNCKLL MSMEG_0408|M.smegmatis_MC2_155 PQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVL Mvan_1003|M.vanbaalenii_PYR-1 PQRTLVCNRSGEVLSRHARLDGQYWRRHARQPVRFAESVRTLADLGCRLL MMAR_3025|M.marinum_M SRTAFFSSVTGSRLD-TAELDAEYWYRNIRQTVQFDQAVRSACGHGYRTF MUL_2266|M.ulcerans_Agy99 SRTAFFSSVTGSRLD-TAELDAEYWYRNIRQTVQFDQAVRSACGHGYRTF Mb2074c|M.bovis_AF2122/97 TRTVFFSTVTGNRLD-TAGLDADYWYRNVRQTVLFDQAVRNACEQGYRTF Rv2048c|M.tuberculosis_H37Rv TRTVFFSTVTGNRLD-TAGLDADYWYRNVRQTVLFDQAVRNACEQGYRTF MAV_2450|M.avium_104 SRIAFFSTVTGNRLD-TAGLDADYWYRNIRQTVQFDQTVRSAAEHGYRTF MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK VEIGPRPVLTAAALSAWP----DPATSPRVIASLRRTTADQRQITEAVAD MSMEG_0408|M.smegmatis_MC2_155 LEIGPRPVLTATALAAWP----DPATTPQVLASLRPTTADHRQITEAVAA Mvan_1003|M.vanbaalenii_PYR-1 MEIGPQPVLTAAAMRTWP----GTVTAPRVAASMRRKGSDRRQITEALAQ MMAR_3025|M.marinum_M IESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGREDGGLQRFLASAAA MUL_2266|M.ulcerans_Agy99 IESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGREDGGLQRFLASAAA Mb2074c|M.bovis_AF2122/97 IESSPHPALITGVEETFAACTDGD-SEAIVVPTLGRGDGGLHRFLLSAAS Rv2048c|M.tuberculosis_H37Rv IESSPHPALITGVEETFAACTDGD-SEAIVVPTLGRGDGGLHRFLLSAAS MAV_2450|M.avium_104 IESSPHPALVAGIEDTVNDSLPGD-TEAIVIPTLGRDDGGLERFLTSAAT MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK AYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDSR------EPVAA MSMEG_0408|M.smegmatis_MC2_155 AYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTASA Mvan_1003|M.vanbaalenii_PYR-1 AYVAGHRPETAARQHGRGRLLDLPTYPFQHRAYWFPQGQ--------ART MMAR_3025|M.marinum_M AFVAGVNVDWRGPLDG-AGLVELPTYAFEKRRFWLSGEGVSVDASGLGLS MUL_2266|M.ulcerans_Agy99 AFVAGVNVDWRGPLDG-AGLVELPTYAFEKRRFWLSGEGVSVDASGLGLS Mb2074c|M.bovis_AF2122/97 AFVAGVAVNWRGTLDG-AGYVELPTYAFDKRRFWLSAEGSGADVSGLGLG Rv2048c|M.tuberculosis_H37Rv AFVAGVAVNWRGTLDG-AGYVELPTYAFDKRRFWLSAEGSGADVSGLGLG MAV_2450|M.avium_104 AFVAGVNVAWRGVLDG-AGFVELPTYAFDRRRFWLSGEGAAADASGLGLG MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK APQRGARTETVRLLEDGRIEELAALLGG---------------------- MSMEG_0408|M.smegmatis_MC2_155 GSVTPHRTQAVRLLEDGQIEELAALIDG---------------------- Mvan_1003|M.vanbaalenii_PYR-1 APTDPVHTETVRFLDEERIDELAALLDG---------------------- MMAR_3025|M.marinum_M AGGHALLGAVVELPESGGVVLTGRLALGAHGWLADHAVSGVVVFPGTGFV MUL_2266|M.ulcerans_Agy99 AGGHALLGAVVELPESGGVVLTGRLALGAHGWLADHAVSGVVVFPGTGFV Mb2074c|M.bovis_AF2122/97 ASEHPLLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDVVLFPGTGFV Rv2048c|M.tuberculosis_H37Rv ASEHPLLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDVVLFPGTGFV MAV_2450|M.avium_104 TSEHPLLSAVVELPASGGVVLTGRLSPSLQGWLTDHAVSGTVVFPGAGFV MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK ----TVDDPFTFDVLNRLAAQHNQQRSTE--------------------- MSMEG_0408|M.smegmatis_MC2_155 ----ETVDEQTLRVLNKLAARHNQQRSTH--------------------- Mvan_1003|M.vanbaalenii_PYR-1 ----PTGSAQTVDVLSKLAARHRQQRGAQ--------------------- MMAR_3025|M.marinum_M ELAIRAGDEVGCSVVNELTLRTPLVLPAS----GSVAVQVVVGAAADSAE MUL_2266|M.ulcerans_Agy99 ELAIRAVDEVGCSVVNELTLRTPLVLPAS----GSVAVQVVVGAAADSAE Mb2074c|M.bovis_AF2122/97 ELAIRAGDEVGCSVLDELTLAAPLLLPAT----GSVAVQVVVDAGRDSNS Rv2048c|M.tuberculosis_H37Rv ELAIRAGDEVGCSVLDELTLAAPLLLPAT----GSVAVQVVVDAGRDSNS MAV_2450|M.avium_104 ELAIRAGDEVGCSTVEELTLQAPLMLPAKDSGIGSVAVQVLVGEADESGR MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK --------------SIADDRYQIRWETAAEPPVGADAADGITWLLVGDDT MSMEG_0408|M.smegmatis_MC2_155 --------------VDPDARYEIRWDAIASAAASTGAAA--DWILVGDDT Mvan_1003|M.vanbaalenii_PYR-1 --------------SIADARYQIRWEKSEAPGAARPTTEATTWLLVTHDS MMAR_3025|M.marinum_M RSVSIYSR----TDTDAGSVWVCHAEGTLGADSAQPAADLSAWPPAGAIA MUL_2266|M.ulcerans_Agy99 RSVSIYSRTDTDTDTDAGSVWVCHAEGTLGADSAQPAADLSAWPPAGAIA Mb2074c|M.bovis_AF2122/97 RGVSIFSR------ADAQAGWLLHAEGILRPGSVEPGADLSVWPPAGAVT Rv2048c|M.tuberculosis_H37Rv RGVSIFSR------ADAQAGWLLHAEGILRPGSVEPGADLSVWPPAGAVT MAV_2450|M.avium_104 RDVSIFSR------PDSDSPWVCHAQGTLSTGSIEPGADLAAWPPAGATK MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK DATRPLVDVLAARGHRY--RILGLPKSGAEEHELADTLRDAAADATDL-- MSMEG_0408|M.smegmatis_MC2_155 AAVLEFADALTAGGHRH--QIVALPGSDADEAQLVDTLR--AASAGEL-- Mvan_1003|M.vanbaalenii_PYR-1 RAAQPIAEVLERRGHPY--HIVGLPGSDADAAPAEEALR-ATVSQPRP-- MMAR_3025|M.marinum_M VDVADGYERLDARGYGYGPAFRGLTAMWARGEELFAEVRLPEAAGSTSGF MUL_2266|M.ulcerans_Agy99 VDVADGYERLDARGYGYGPAFRGLTAMWARGEELFAEARLPEAAGSTSGF Mb2074c|M.bovis_AF2122/97 VDVADGYERLATRGYRYGPAFRGLTAMWARGEEIFAEVRLPEAAGGVGGF Rv2048c|M.tuberculosis_H37Rv VDVADGYERLATRGYRYGPAFRGLTAMWARGEEIFAEVRLPEAAGGVGGF MAV_2450|M.avium_104 VDIADGYQRLAARGYGYGPAFQGLTAAWVRGDEVFAEVRLPDAAGGVTGF MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1003|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3025|M.marinum_M GVHPALLDAALHTAVI----ANPDAELVLPFSWQGVSLHAAGAASVRVRI MUL_2266|M.ulcerans_Agy99 GVHPALLDAALHTAVI----ANPDADLVLPFSWQGVSLHAAGAASVRVRI Mb2074c|M.bovis_AF2122/97 GVHPALLDAVLHAVVI----AGDPDELALPFAWQGVSLHATGASAVRARI Rv2048c|M.tuberculosis_H37Rv GVHPALLDAVLHAVVI----AGDPDELALPFAWQGVSLHATGASAVRARI MAV_2450|M.avium_104 GVHPALLDAAMHALIVGHQIAGDTDEVALPFAWQGVSLHAAGASAVRARL MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1003|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3025|M.marinum_M APVGPS------SVSVELADDLGLPVLSVKAMVARPVSEQQMRAVVSASG MUL_2266|M.ulcerans_Agy99 APVGPS------SVSVELADDLGLPVLSVKAMVARPVSEQQMRAVVSASG Mb2074c|M.bovis_AF2122/97 APAGPS------AVSVELADGLGLPVLSVASMVARPVTERQLLAAVSGSG Rv2048c|M.tuberculosis_H37Rv APAGPS------AVSVELADGLGLPVLSVASMVARPVTERQLLAAVSGSG MAV_2450|M.avium_104 APAQAPGTAASRAVSLELADGLGLPVLSVRAMVARSVSERQLRAAVSAAG MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK ----------RIVHVAALDAAESDTSMKSLLRMQHRVLGGTRRLFGAAVA MSMEG_0408|M.smegmatis_MC2_155 ----------YVVHIAAGDGAAAP--MRDLLRVQHRTLGGLRRLFRAAND Mvan_1003|M.vanbaalenii_PYR-1 ----------HILYLAALEEPGGS-AAETLGWMQHRVLAAARRLFQLAAT MMAR_3025|M.marinum_M PDRLFEVVWTPMTVAAT-DAAPAYELFESVAAEGDPLSGTYQRTHQALAA MUL_2266|M.ulcerans_Agy99 PDRLFEVVWTPMTVAAT-DAAPAYELFESIAADGDPLSGTYQRTHQALAA Mb2074c|M.bovis_AF2122/97 PDRLFEVIWSPASAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQALAA Rv2048c|M.tuberculosis_H37Rv PDRLFEVIWSPASAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQALAA MAV_2450|M.avium_104 PDRLFEVAWAPVTVPAAHGEPPVHQVFESLAAEGDPVGESYRRTHEALAA MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK AQ------LRSPMWLVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHP-- MSMEG_0408|M.smegmatis_MC2_155 AE------LRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELP-- Mvan_1003|M.vanbaalenii_PYR-1 AG------ARAPIWLITAGAQRITGDETVEPAQTSLWGFGRAAALEQP-- MMAR_3025|M.marinum_M VQSWLTEHDSGVLVVATRGAMALAGEDVTDLAGAAVWGLVRSAQTENPGR MUL_2266|M.ulcerans_Agy99 VQSWLTEHDSGVLVVATRGAMALAGEDVTDLAGAAVWGLVRSAQTENPGR Mb2074c|M.bovis_AF2122/97 VQSWLTDHESGVLVVATRGAMALPREDVADLAGAAVWGLVRSAQTEHPGR Rv2048c|M.tuberculosis_H37Rv VQSWLTDHESGVLVVATRGAMALPREDVADLAGAAVWGLVRSAQTEHPGR MAV_2450|M.avium_104 VQSWLTEHDSGVLVVVTRGAMALAGEDVTDLSGAAVWGLVRSAQTEHPGR MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1003|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3025|M.marinum_M LVLVDSDAAVDAAAVATALAVGEPQVVLRNGQPYTARVHASRAADGILVP MUL_2266|M.ulcerans_Agy99 LVLVDSDAAVDAAAVATALAVGEPQVVLRNGQPYTARVHASRAADGILVP Mb2074c|M.bovis_AF2122/97 IVLVDSDAATDDAAIAMALATGEPQVVLRGGQVYTARVRGSRAADAILVP Rv2048c|M.tuberculosis_H37Rv IVLVDSDAATDDAAIAMALATGEPQVVLRGGQVYTARVRGSRAADAILVP MAV_2450|M.avium_104 IVLIDSDAALDDSALTAALATGEPQVLLRDGTVYTARVHGSRAVDGIMTP MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1003|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3025|M.marinum_M PVDGPWRLGLSSAGTFENLQLEPVPNAGAPLGPGQVRVAMRAIAANFRDI MUL_2266|M.ulcerans_Agy99 PVDGPWRLGLSSAGTFENLQLEPVPNAGAPLGPGQVRVAMRAIAANFRDI Mb2074c|M.bovis_AF2122/97 PGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMRAIAANFRDI Rv2048c|M.tuberculosis_H37Rv PGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMRAIAANFRDI MAV_2450|M.avium_104 PEDRPWRLGISSAGTFENLQLEPVPNPDAALQPGQVRVALRAIATNFRDV MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1003|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3025|M.marinum_M MITLGMFTHDALIGGEGAGVVVEIGPEVTEFAVGDAVYGFFPDGSGTLVA MUL_2266|M.ulcerans_Agy99 MITLGMFTHDALIGGEGAGVVVEIGPEVTEFAVGDAVYGFFPDGSGTLVA Mb2074c|M.bovis_AF2122/97 MITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFFPDGSGTLVA Rv2048c|M.tuberculosis_H37Rv MITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFFPDGSGTLVA MAV_2450|M.avium_104 MITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVYGFFPDGSGTLVP MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1003|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3025|M.marinum_M GDVRLLLPKPADWSYAEAAAISAVFTTAYYAFVHLANVQPGQRVLVHAAT MUL_2266|M.ulcerans_Agy99 GDVRLLLPKPADWSYAEAAAISAVFTTAYYAFVHLANVQPGQRVLVHAAT Mb2074c|M.bovis_AF2122/97 GDVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQPGQRVLIHAGT Rv2048c|M.tuberculosis_H37Rv GDVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQPGQRVLIHAGT MAV_2450|M.avium_104 GDVRLLQHKPTHWSYPEAAGISAVFTTAYMAFIHLADVKPGQRVLVHAAA MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK ----------QIWGGLADLGGGTSDEWSRLLNR------IAATHDPAVME MSMEG_0408|M.smegmatis_MC2_155 ----------HIWGGLADLSG-ADTEWPRLIAR------ITSPRD---GE Mvan_1003|M.vanbaalenii_PYR-1 ----------ELWGGLADVTTGDAEEWSALIDH------IVAAPT---SE MMAR_3025|M.marinum_M GGVGMAAVQLARHLGLEVYATASKGKWDILRAMGFDEDHISDSRSLEFEE MUL_2266|M.ulcerans_Agy99 GGVGMAAVQLARHLGLEVYATASKGKWDILRAMGFDEDHISDSRSLEFEE Mb2074c|M.bovis_AF2122/97 GGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEFED Rv2048c|M.tuberculosis_H37Rv GGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEFED MAV_2450|M.avium_104 GGVGMAAVQLARHLGLEVFATASRGKWDTLRAMGFDDDHIGDSRTLEFED MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK DQVAVRGSTSYVPRLVHRDTLPSGKPLHLRA------------------- MSMEG_0408|M.smegmatis_MC2_155 DQIALRGDAVYAPRLVRRTGEPSDTPLPVRE------------------- Mvan_1003|M.vanbaalenii_PYR-1 DQIAVRGREIHVARLTRCAEKANAAALELRR------------------- MMAR_3025|M.marinum_M KFREVTGGRGVDVVLDSLAGEFVDASLRLLGPGGVFLEMGKTDIRDPGVI MUL_2266|M.ulcerans_Agy99 KFREVTGGRSVDVVLDSLAGEFVDASLRLLGPGGVFLEMGKTDIRDPGVI Mb2074c|M.bovis_AF2122/97 KFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGVI Rv2048c|M.tuberculosis_H37Rv KFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGVI MAV_2450|M.avium_104 KFRSATGGAGMDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGVV MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0408|M.smegmatis_MC2_155 -------------------------------------------------- Mvan_1003|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_3025|M.marinum_M AQEYPGVRYRAFDLFEPGRPRMHQYMLDLAGLFDAGVLRPLPVTAFDVRR MUL_2266|M.ulcerans_Agy99 AQEYPGVRYRAFDLFEPGRPRMHQYMLDLAGLFDAGVLRPLPVTAFDVRR Mb2074c|M.bovis_AF2122/97 AQQYPGVRYRAFDLFEAGPDRIAQILAELATLFGDGVLRPLPVTTFDVRR Rv2048c|M.tuberculosis_H37Rv AQQYPGVRYRAFDLFEPGRPRMHQYMLELATLFGDGVLRPLPVTTFDVRR MAV_2450|M.avium_104 AREYPGVRYRAFDLFEPGRPRMRQWMVELAGLFDAGVLNPLPVTTFDIRR MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK ------------------------------DATYLVTGGLGSLGLEIAGY MSMEG_0408|M.smegmatis_MC2_155 ------------------------------DRTYLVTGGLGAIGLEVAGY Mvan_1003|M.vanbaalenii_PYR-1 ------------------------------EATYLVTGGLGALGLEVAEF MMAR_3025|M.marinum_M APAALRYLSQARHIGKVVMTMPADQGGALGGGTVLITGGTGMAGSALARH MUL_2266|M.ulcerans_Agy99 APAALRYLSQARHVGKVVMTMPADQGGALGGGTVLITGGTGMAGSALARH Mb2074c|M.bovis_AF2122/97 APAALRYLSQARHTGKVVMLMPG----SWAAGTVLITGGTGMAGSAVARH Rv2048c|M.tuberculosis_H37Rv APAALRYLSQARHTGKVVMLMPG----SWAAGTVLITGGTGMAGSAVARH MAV_2450|M.avium_104 GRAALRYLSQARHIGKVVMTVPG----ALSAGTVLITGGTGMAGSTLARH MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK LAA-NGAGHLVLTSRRTPDEAAASRIEALRERHGCEVRVVTADVADAHAV MSMEG_0408|M.smegmatis_MC2_155 LAS-HGAGHVVLTSRREPGDDARRRLDGLREQYACDVRVITADVADAHDV Mvan_1003|M.vanbaalenii_PYR-1 LAS-HGAGHLVLTGRRSASDTVRQRIDAMRERFDCQVLVATADVADRDDV MMAR_3025|M.marinum_M LVAHHGVAHLVLISRRGPAAPGATELVAELSAAGAQVEVVACDAADRPAL MUL_2266|M.ulcerans_Agy99 LVAHHGVAHLVLISRRGPAAPGATELVAELSAAGAQVEVVACDAADRPAL Mb2074c|M.bovis_AF2122/97 VVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRAAL Rv2048c|M.tuberculosis_H37Rv VVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRAAL MAV_2450|M.avium_104 LVTGHGVRDLALLSRTGPDAPGAAEFVAELEAAGARVQVIACDAADRAAL MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK ARLLATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVDRVFAGKVWGAWH MSMEG_0408|M.smegmatis_MC2_155 ARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWH Mvan_1003|M.vanbaalenii_PYR-1 ARLFSTMRSELPPLAGIVHAAGEIGTSPLRTLDDAEMDRVFAGKVWGAVY MMAR_3025|M.marinum_M AKVIAEIPAQRP-LSAVVHAGGVLDDAVISSLTPERVDTVLRAKVDAAWN MUL_2266|M.ulcerans_Agy99 AKVIAENPAQRP-LSAVVHAGGVLDDAVISSLTPERVDTVLRAKVDAAWN Mb2074c|M.bovis_AF2122/97 AKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAAWH Rv2048c|M.tuberculosis_H37Rv AKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAAWH MAV_2450|M.avium_104 AGVIAGISAERP-LSGVIHAAGVLDDAMITSLTPERIDAVLRAKVDAAWN MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK LSEATSDLQ--LDFFISTSSIASVWGGFGQAAYGAANAFLDGLAWRLREQ MSMEG_0408|M.smegmatis_MC2_155 LSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRER Mvan_1003|M.vanbaalenii_PYR-1 LCEEVADMG--LDFFLATSSIASVWGSHGQTAYGAANAFLDGLADSLRAR MMAR_3025|M.marinum_M LHELTRDLD--LSAFVMFSSMAGVVGSSGQANYAAANTFVDGLAAHRRAH MUL_2266|M.ulcerans_Agy99 LHELTRDLD--LSAFVMFSSMAGVVGSSGQANYAAANTFVDGLAAHRRAH Mb2074c|M.bovis_AF2122/97 LHELTRDLD--VSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRRAH Rv2048c|M.tuberculosis_H37Rv LHELTRDLD--VSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRRAH MAV_2450|M.avium_104 LHELTRDMN--LSAFVMFSSMAGLVGSSGQGNYAAANSFLDALAAHRRAH MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK GVAGVSVNFGPWSAG-----MADAQSRARLEQRGIKTLSPADALAGLSDA MSMEG_0408|M.smegmatis_MC2_155 GVTAVSVNFGPWAAG-----MADAESRARLEQRGVRTLSPAEALAGMADV Mvan_1003|M.vanbaalenii_PYR-1 GIPGISVNFGPWAAG-----MADAKAREQLSRRGVKTLAPADALAGMADV MMAR_3025|M.marinum_M GLPAISLGWGLWDQASDMTGGMDAADRARLGREGVLALSSDEAMELFDTA MUL_2266|M.ulcerans_Agy99 GLPAISLGWGLWDQASDMTGGMDAADRARLGREGVLALSSDEAMELFDTA Mb2074c|M.bovis_AF2122/97 GLPAISLGWGLWDQASAMTSGLDAADLARLGREGVLALSTAEALELFDTA Rv2048c|M.tuberculosis_H37Rv GLPAISLGWGLWDQASAMTGGLDAADLARLGREGVLALSTAEALELFDTA MAV_2450|M.avium_104 GLPAISLAWGLWDQASAMTGGLDAADLARLGRDGILALSSDEAMELFDTA MLBr_00135|M.leprae_Br4923 -----------------MTASVEGADQK---------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK VISAAPHPVVARVDWSRFLPLYQQAGRRGFLAELERELPAAPAQQGPAVT MSMEG_0408|M.smegmatis_MC2_155 VAGPVQG-VVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATGAAAPAT Mvan_1003|M.vanbaalenii_PYR-1 IAASTAHAVVARIDWATFLPVYQLQRRRAFLSQLEREVPDVPDASAPAP- MMAR_3025|M.marinum_M LIVNQAFLAPARIDLA---ALRAHAVAVPPMFSDLVSAPTRRQVDDALAA MUL_2266|M.ulcerans_Agy99 LIVNQAFLAPARIDLA---ALRAHAVAVPPMFSDLVSAPTRRQIDAALAT Mb2074c|M.bovis_AF2122/97 MIVDEPFLAPARIDLT---ALRAHAVAVPPMFSDLASAPTRRQVDDSVAA Rv2048c|M.tuberculosis_H37Rv MIVDEPFLAPARIDLT---ALRAHAVAVPPMFSDLASAPTRRQVDDSVAA MAV_2450|M.avium_104 LIVDEPFLAPARIDLG---ALRAHAVAVPPMFADLVNAPTRRRVDDSLAA MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK ASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTR-VDAAEIREDAGFF MSMEG_0408|M.smegmatis_MC2_155 VPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAEVTR-VDADEIRDEAGFF Mvan_1003|M.vanbaalenii_PYR-1 -SGTTRFVEELTLAPVEQRRKLVLEYLRAAVAEVTR-VDAAEIRDEAGFF MMAR_3025|M.marinum_M AKSKSALAHRLHGLPEPEQHAVVLDLVRSHIATVLGTITPEAIDPDKAFQ MUL_2266|M.ulcerans_Agy99 AKSKSALAHRLHGLPELEQHAVVLDLVRSHIATVLGTITPEAIDPDKAFQ Mb2074c|M.bovis_AF2122/97 AKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQ Rv2048c|M.tuberculosis_H37Rv AKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQ MAV_2450|M.avium_104 AKSKSALAHRLDGLPEAEQHAVLLELVRSHIATVLGSPTAEAIDPDKAFQ MLBr_00135|M.leprae_Br4923 -------------------------------------------------- MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK DLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYLLGDVLGLT MSMEG_0408|M.smegmatis_MC2_155 DLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLG Mvan_1003|M.vanbaalenii_PYR-1 DLGMDSLMAIELRRRLEQGLGKELPVTLAMDHPHLSDAAEYVLGDVLGLS MMAR_3025|M.marinum_M ELGFDSLTAVEMRNRIKTVTGLSLSPTLIFDYPTPNGLANYIRAELAGAP MUL_2266|M.ulcerans_Agy99 ELGFDSLTAVEMRNRIKTVTGLSLSPTLIFDYPTPNGLANYIRAELAGAP Mb2074c|M.bovis_AF2122/97 DLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAGLP Rv2048c|M.tuberculosis_H37Rv DLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAGLP MAV_2450|M.avium_104 ELGFDSLTAVEMRNRLKTATGLALSPTLIFDYPTPNALAGYIRTELAGAP MLBr_00135|M.leprae_Br4923 ----------------------------------SEKLISYLKKVVVELD MAB_3148c|M.abscessus_ATCC_199 -------------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK EAATAPKAATVVSTAADEPIAIVAVSCRFPG-APNPEAFWDLLSGGVDAI MSMEG_0408|M.smegmatis_MC2_155 EQTNVRQASTVT-ARTDDPIAVVAVSCRFPG-APDPESFWELLAGGVDAI Mvan_1003|M.vanbaalenii_PYR-1 EHT-VAQPDTPSTVRTDDPIAIVGMACRFPG-ADDTDAFWSVLAEGADLI MMAR_3025|M.marinum_M QEVKHTPAVRVT---GDDPIAIVGMSCRYPGGIESPDDLWDMLMARRDVL MUL_2266|M.ulcerans_Agy99 QEVKHTPAVRVT---GDDPIAIVGMSCRYPGGIESPDDLWDMLMARRDVL Mb2074c|M.bovis_AF2122/97 QEIKHTPAVRTT---SEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVL Rv2048c|M.tuberculosis_H37Rv QEIKHTPAVRTT---SEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVL MAV_2450|M.avium_104 QETTHAPVVRAT---DDDPIAIVGMSCRFPGGVDSPEALWQMVAEGRDVL MLBr_00135|M.leprae_Br4923 ETRARLREYEQR---ATEPVAVVGIGCRFPGGVDSPDRLWDVVSECRDVV MAB_3148c|M.abscessus_ATCC_199 ------------------------MGCRLPGGIESPEQFWQALLRGEDFI TH_4621|M.thermoresistible__bu --------VNIVGDTPVNAVAVIGMACRLPGGIDSPQRLWEALLRGDDMV :.** ** ..: :*. : * : Mflv_0405|M.gilvum_PYR-GCK REVPEDR-FDIDEFYDPDPDAAGKTYTRYGGFLDHIDEFDPEFFGLSPRE MSMEG_0408|M.smegmatis_MC2_155 REVPEDR-WDIDEFYDPDPDTPGKTYTRFGGFLDGIDGFDPEFFGISPRE Mvan_1003|M.vanbaalenii_PYR-1 REIPDDR-FDINEFYDPDPEAAGKIYSRYGGFLDGVDGFDPEFFGISPRE MMAR_3025|M.marinum_M SDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFDPAFFGVGPSE MUL_2266|M.ulcerans_Agy99 SDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFEPAFFGVGPSE Mb2074c|M.bovis_AF2122/97 SEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSE Rv2048c|M.tuberculosis_H37Rv SEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSE MAV_2450|M.avium_104 SEFPTDRGWDLAGVYNPDPDVPGTCYTRTGGFVDNVADFDPAFFGIAPSE MLBr_00135|M.leprae_Br4923 SEFPTDRGWDVDGLFDPDPDAEGKTYTRWGAFLDDAAGFDAGFFGIAPSE MAB_3148c|M.abscessus_ATCC_199 TEVPPAR-WDLTEYYDPESGVPGKSPSKWGAFLEDVGGFDADFFSINERE TH_4621|M.thermoresistible__bu TEIPVDR-WDADDYFDPEPGVPGRTVSRWGAFLDDVAGFDPEFFGISERE :.* * :* ::*:. . * :: *.*:: *:. **.: * Mflv_0405|M.gilvum_PYR-GCK AVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTGVFVGVAANEYAHLLS MSMEG_0408|M.smegmatis_MC2_155 AVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLS Mvan_1003|M.vanbaalenii_PYR-1 AVWIDPQQRLVLETAWEGLERAGYSAAALRGSRSGVYVGVGANEYSHLLS MMAR_3025|M.marinum_M ALAMDPQQRMFLELSWEALERAGIEPGGLRGSATGVFAGVMTQGYGMFAA MUL_2266|M.ulcerans_Agy99 ALAMDPQQRMFLELSWEALERAGIEPGGLRGSATGVFAGVMTQGYGMFAA Mb2074c|M.bovis_AF2122/97 ALAMDPQQRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMFAA Rv2048c|M.tuberculosis_H37Rv ALAMDPQHRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMFAA MAV_2450|M.avium_104 ALAMDPQQRMFLELSWEALERAGIDPVKLRGSATGMFAGVYTQGYGMGAA MLBr_00135|M.leprae_Br4923 VLAMDPQQRLMLEVSWEALEYAGIDPLSLRGSATGVFTGIFAPSYGSRDT MAB_3148c|M.abscessus_ATCC_199 AVSIDPQHRVLLETSWQAVEHAGIDPRALAGSQTGVFVGVTHNDYQLVAA TH_4621|M.thermoresistible__bu AISIDPQQRLLLETSWEAMEHAGLTPADVEGSSTGVFVGLSHDDYALLTS .: ::**:*:.** *:.:* ** . : ** :*::.*: * : Mflv_0405|M.gilvum_PYR-GCK AESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTACSSSLVAVHQ MSMEG_0408|M.smegmatis_MC2_155 AESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQ Mvan_1003|M.vanbaalenii_PYR-1 GGSLDGIEAQFITGNALNVIAGRVSFTLGLEGPAVAVDTACSSSLVAVHQ MMAR_3025|M.marinum_M EP----VEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHM MUL_2266|M.ulcerans_Agy99 EP----VEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHM Mb2074c|M.bovis_AF2122/97 EP----VEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHM Rv2048c|M.tuberculosis_H37Rv EP----VEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHM MAV_2450|M.avium_104 PI----AEGFRLTGQSSSVASGRVSYVLGLEGPAVSVDTACSSSLVALHM MLBr_00135|M.leprae_Br4923 GG----LQGYGLTGTAVSVASGRVSYVLGLEGPAVSVDTACSSSLVAIHW MAB_3148c|M.abscessus_ATCC_199 DAA-DLGGPYGFAGTNFCMASGRISYALGVHGPSLTVDAGCAAGLATVHM TH_4621|M.thermoresistible__bu DAG-ALEEAYGFTGSAFSMASGRIAYRLGVHGPAVTVDTACSSSLLAVHM ::* :**::: **..**:::**:.*::.* ::* Mflv_0405|M.gilvum_PYR-GCK ATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASAD MSMEG_0408|M.smegmatis_MC2_155 ACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASAD Mvan_1003|M.vanbaalenii_PYR-1 ACQGLQSGDCDLALAGGVNVLLSPATTIATSRARMLSPDGRCKTFDAAAD MMAR_3025|M.marinum_M AVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLSADGRCKAFAGAAD MUL_2266|M.ulcerans_Agy99 AVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLSADGRCKAFAGAAD Mb2074c|M.bovis_AF2122/97 AVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAAD Rv2048c|M.tuberculosis_H37Rv AVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAAD MAV_2450|M.avium_104 AVQSLRSGECDLALAGGVTVNATPDIFVEFSRMRGLSVDGRCKAYAGAAD MLBr_00135|M.leprae_Br4923 AMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFARAAD MAB_3148c|M.abscessus_ATCC_199 GCQSLAAGESDLVLAGGVNLVLEPRRYVGASQQRMLSPTGRCHTFTGEAD TH_4621|M.thermoresistible__bu ACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGMLSPTGRCHAFDVAAD . .* *:.*:.****. : * * *: ***::: ** Mflv_0405|M.gilvum_PYR-GCK GYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGASSGLTVPNGG MSMEG_0408|M.smegmatis_MC2_155 GYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGG Mvan_1003|M.vanbaalenii_PYR-1 GYVRGEGCGILVLKRLSDAVRDGDRIQAVIRGSAVNQDGASGGLTVPNGG MMAR_3025|M.marinum_M GTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQDGASNGLTAPNGP MUL_2266|M.ulcerans_Agy99 GTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQDGASNGLTAPNGP Mb2074c|M.bovis_AF2122/97 GTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGP Rv2048c|M.tuberculosis_H37Rv GTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGP MAV_2450|M.avium_104 GTGFSEGGGMLVVERLSDARRLGHPVLAVVRGSAVNQDGASNGLTAPNGP MLBr_00135|M.leprae_Br4923 GTGWGEGAGVVVLERLSDAQRLGHTVLAVVRGSAVNQDGASNGLTAPNGL MAB_3148c|M.abscessus_ATCC_199 GFVMSEGCVMVLLKRLDDAVRDGDRILAVVRGTASNQDGRTVNQSTPSSE TH_4621|M.thermoresistible__bu GFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAANQDGRTENISTPSIQ * .** :::::** ** * .. : *:: .:: **** : . :.*. Mflv_0405|M.gilvum_PYR-GCK AQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQAAAAAYAGARD MSMEG_0408|M.smegmatis_MC2_155 AQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQAAAAAYGAGRD Mvan_1003|M.vanbaalenii_PYR-1 AQQRVIAAALTRAGLSGSDIDYLEAHGTGTSLGDPIEVQAAGAVLGAGRD MMAR_3025|M.marinum_M SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRG MUL_2266|M.ulcerans_Agy99 SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRG Mb2074c|M.bovis_AF2122/97 SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRG Rv2048c|M.tuberculosis_H37Rv SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRG MAV_2450|M.avium_104 SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRG MLBr_00135|M.leprae_Br4923 AQQRVIQAALTNAGLSSADVDVVEAHGTATTLGDPIEAQALLATYGQGRP MAB_3148c|M.abscessus_ATCC_199 AQAAACRTALAVAGVEADTVGLIEAHGTGTPVGDPIEYTGLAQVYGVDGP TH_4621|M.thermoresistible__bu AQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDPIEYNSLTQVYGKTGP :* :.*: **: :. :*.***.*.:***** . . . Mflv_0405|M.gilvum_PYR-GCK AD----RPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHETLPQSLHFDT MSMEG_0408|M.smegmatis_MC2_155 AD----RPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFEN Mvan_1003|M.vanbaalenii_PYR-1 PD----RPLLMGSVKTNVGHLESASGVAGLIKVVLSLQHEMLPRHLHFKT MMAR_3025|M.marinum_M SAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVLPATLHVDV MUL_2266|M.ulcerans_Agy99 SAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVLPATLHVDV Mb2074c|M.bovis_AF2122/97 EP---GEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDV Rv2048c|M.tuberculosis_H37Rv EP---GEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDV MAV_2450|M.avium_104 QP------LWLGSIKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDE MLBr_00135|M.leprae_Br4923 AD----QPLWVGSIKSNMGHTQAAAGVAGVIKMVQAMRHHVMPATLHVDE MAB_3148c|M.abscessus_ATCC_199 CA--------VGSVKTNFGHTMSAAGALGLMKIVLAVEHGVVPPNLHFTG TH_4621|M.thermoresistible__bu CA--------LTSVKTNFGHAESAAGALGMMKAILALQHGVVPQNLHFTR : *:*:*.** :*:*. *::* : ::.* :* **. Mflv_0405|M.gilvum_PYR-GCK PSPHIPWDSLPVRVVDTAMPWQ---PNGRPRRAGVSSFGFTGTNAHVLIE MSMEG_0408|M.smegmatis_MC2_155 PSPHIPWDALPVRVIDEPVPWQ---TNGRVRRAGVSSFGFTGTNAHVLVE Mvan_1003|M.vanbaalenii_PYR-1 PSPHIPWDRLAVRVVAEPTPWR---ADGRPRRAGVSSFGFSGTNAHVVLE MMAR_3025|M.marinum_M PSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAHVIVE MUL_2266|M.ulcerans_Agy99 PSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAHVIVE Mb2074c|M.bovis_AF2122/97 PSPHVDWSAGAVELLTAPRVWP---AGARTRRAGVSSFGISGTNAHVIIE Rv2048c|M.tuberculosis_H37Rv PSPHVDWSAGAVELLTAPRVWP---AGARTRRAGVSSFGISGTNAHVIIE MAV_2450|M.avium_104 PSPHVDWSAGAVSLLTEAQPWP----GERPRRAGVSSFGISGTNAHVIIE MLBr_00135|M.leprae_Br4923 PSPRVDWTTGAVSVLTEARDWS---VEGRPRRAGVSSFGISGTNAHVILE MAB_3148c|M.abscessus_ATCC_199 IPDKLAPVKTNLFVPQTVIPWP--GKAQGPRRAGVSAYGMSGSNVHAVVE TH_4621|M.thermoresistible__bu LPDEMAAIETNLFVPQATTLWP--VREGCPRRAAVSSYGMSGTNVHAVLE . .: : : * ***.**::*::*:*.*.::* Mflv_0405|M.gilvum_PYR-GCK EAPTDLAGPTEPTAPAE-PVDEDAAADP-APAPVEVLPLSARSPEALVAL MSMEG_0408|M.smegmatis_MC2_155 EAPPQLH-----TADAA-PVEPAATAEAGTDDSPQVLALSARSPEALVEL Mvan_1003|M.vanbaalenii_PYR-1 EPPAQSADLRQPPTDGK--DGAAGLESATAPEPAGVLPISARSPEALTAL MMAR_3025|M.marinum_M AAP-----------------RVEVGGSSGGAVPVVPWVVSAKSGSALGAQ MUL_2266|M.ulcerans_Agy99 AAP-----------------RVEVGGSSGGAVPVVPWVVSAKSGSALGAQ Mb2074c|M.bovis_AF2122/97 AVP-----------------VVPRR-EAGWAGPVVPWVVSAKSESALRGQ Rv2048c|M.tuberculosis_H37Rv AVP-----------------VVPRR-EAGWAGPVVPWVVSAKSESALRGQ MAV_2450|M.avium_104 AVP-----------------AVEPAHADAPALPVLPWVVSAKSAAALRAQ MLBr_00135|M.leprae_Br4923 EAP--------------TPVEASYSTADQQRLSVVPWVVSGRSTAALMAQ MAB_3148c|M.abscessus_ATCC_199 QAP--------------PVESSTPPAVESPLGSQLIFPVSSTSAEELRRT TH_4621|M.thermoresistible__bu QAP--------------EPVQRPEESADTDAAGPLVFALSSTSAEELRRT * :*. * * Mflv_0405|M.gilvum_PYR-GCK AQRYETWLTAHP-EADLADVCRTAGTGRSHFEHRAALVVDSVESARIALT MSMEG_0408|M.smegmatis_MC2_155 ARRYDDWLSATP-GLDIADVCHTAGVGRSHFEYRAALVVDSVERAREGLA Mvan_1003|M.vanbaalenii_PYR-1 ARRYESWLTAHP-DADIADVCYTAGAGRSHFEHRAALVVDSVDGARDLLA MMAR_3025|M.marinum_M AARLAAHVRSHD-ELDVADVGWSLAG-RSTFEHRAVVLGVDRDGLLAGLD MUL_2266|M.ulcerans_Agy99 AARLAAHVRSHD-ELDVADVGWSLAG-RSTFEHRAVVLGADRDGLLAGLD Mb2074c|M.bovis_AF2122/97 AARLAAYVRGDD-GLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLLAGLD Rv2048c|M.tuberculosis_H37Rv AARLAAYVRGDD-GLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLLAGLD MAV_2450|M.avium_104 AARLAEYVRAQG-ELDIADVGWTLAG-RATFEHRAVVVGGDRDRLLAGLD MLBr_00135|M.leprae_Br4923 ASRLAFYVQADP-EVDPVDVGCALAA-RSVFEHRAVVVGESREQLIAGLA MAB_3148c|M.abscessus_ATCC_199 AARLADWVAERP-EVAPGDVGYTLARRRAHRSVRTAVVADGADELIDALR TH_4621|M.thermoresistible__bu AGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVRTTVIADGVEALTAGLR * * : *: : . *: *:.:: . : * Mflv_0405|M.gilvum_PYR-GCK DLAQNRLR-PGVVRGEHLNHPTTAWMFTGQGSQYPGMARELFDTEPVFAD MSMEG_0408|M.smegmatis_MC2_155 ALAEGRTP-AGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQ Mvan_1003|M.vanbaalenii_PYR-1 GLAEDRLG-PGAVRGVCGDPPKTAWLFTGQGSQYPGMARELFDTEPVFRD MMAR_3025|M.marinum_M ELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHAGYPVFAE MUL_2266|M.ulcerans_Agy99 ELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHAGYPVFAE Mb2074c|M.bovis_AF2122/97 ELAGDQLG-GSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAE Rv2048c|M.tuberculosis_H37Rv ELAGDQLG-GSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAE MAV_2450|M.avium_104 ELAADDPA-ASIIRGVATPAGKTVFVFPGQGSQTLGMGRQLHAGYPVFAE MLBr_00135|M.leprae_Br4923 GLAVGESG-AGVAIGQAAPLGKTVVVFPGQGAQRIGMGRELCSQLPVFAE MAB_3148c|M.abscessus_ATCC_199 GVAEGDAP---YPAAVAQDDRGPVWLFSGQGSQWAGMGAELLGKEPVFAE TH_4621|M.thermoresistible__bu EVADGDAP---YQPAVGMDDKAPVWVFSGQGSQWAGMGAELLATEQVFAA :* . . .. :*.***:* **. * ** Mflv_0405|M.gilvum_PYR-GCK TVTRCADAVADLLPRPLLDVMFAGGREAGVPPTETLRHTSFAQPALFAVE MSMEG_0408|M.smegmatis_MC2_155 TVRQCAEAVADMLPRPLLDVLFATDRET----ADLLQHTSFAQPALFAVE Mvan_1003|M.vanbaalenii_PYR-1 TVTRCAEAIGDTLPRPLLEVLFDTDGDN----GQTLRHTSYAQPALFAIE MMAR_3025|M.marinum_M AFNTVVGELDRHLLRPLREVIWGHDENL-------LNTTEFAQPALFAVE MUL_2266|M.ulcerans_Agy99 AFNTVVGELDRHLLRPLREVIWGHDENL-------LNTTEFAQPALFAVE Mb2074c|M.bovis_AF2122/97 AFNTVVGELDRHLLRPLREVMWGHDENL-------LNSTEFAQPALFAVE Rv2048c|M.tuberculosis_H37Rv AFNTVVGELDRHLLRPLREVMWGHDENL-------LNSTEFAQPALFAVE MAV_2450|M.avium_104 AFDAVVAELDRHLLRPLRDVIWGDDENV-------LNSTEFAQPALFAVE MLBr_00135|M.leprae_Br4923 EFDAVTGELDRHMRLPLRDVVWGADAGL-------LDSTEFAQPALFAVE MAB_3148c|M.abscessus_ATCC_199 TIARLEPLIHAESGFSVTDAISAPETVTG---------IDRVQPTLFAMQ TH_4621|M.thermoresistible__bu KIAEIEPLVARESGFSVTEAMTASETVTG---------IDRVQPTLFAIQ . : .: :.: . .**:***:: Mflv_0405|M.gilvum_PYR-GCK MGLARLWQSWGIVPDVVLGHSVGQYAAACVAGVFSLEDGARLMAERGRLF MSMEG_0408|M.smegmatis_MC2_155 MGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMF Mvan_1003|M.vanbaalenii_PYR-1 MGLARLWQARGIEPDVVLGHSVGQYAAACVAGVFGLEDGARLVADRGRLF MMAR_3025|M.marinum_M VALYRLLESWGVRPDFVMGHSVGELSAAHVAGVLSLENAAVLVAARGRLM MUL_2266|M.ulcerans_Agy99 VALYRLLESWGVRPDFVMGHSVGELSAAHVAGVLSLENAAVLVAARGRLM Mb2074c|M.bovis_AF2122/97 VALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLM Rv2048c|M.tuberculosis_H37Rv VALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLM MAV_2450|M.avium_104 VALFRLLESWGVRPDFVMGHSIGELSAAHVAGVLSLQNAAVLVAARGRFM MLBr_00135|M.leprae_Br4923 VALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPADAAMLVVARGRLM MAB_3148c|M.abscessus_ATCC_199 VSLAATLASYGVRPGAVIGHSMGEVAAAVVSEALSLEDGVKVICRRSQLM TH_4621|M.thermoresistible__bu VALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLEDGVKVICRRSRLC :.* .: *. *:***:*: :** *: .:. :.. :: *.:: Mflv_0405|M.gilvum_PYR-GCK GSLPEGGRMVAVFADAKRVEQVAAD--FPRVSVGAYNGPN-TVLSGPGED MSMEG_0408|M.smegmatis_MC2_155 GSLPEGGRMVAVFADAEHVEQVAGE--FPRVSVGAYNGPN-TVLSGPGED Mvan_1003|M.vanbaalenii_PYR-1 GGLPVGGRMVAVFTDAEVVEDFADE--FPQVSVAAYNGPN-TVLAGPASD MMAR_3025|M.marinum_M QALPDGGAMIAVQATEQEVLPLLG----AQVSIAAINGPASVVISGAQDA MUL_2266|M.ulcerans_Agy99 QALPDGGAMIAVQATEQEVLPLLG----AQVSIATINGPASVVISGAQDA Mb2074c|M.bovis_AF2122/97 QALPAGGAMVAVQAAEEEVRPLLS----AEVDIAAVNGPASLVISGAQNA Rv2048c|M.tuberculosis_H37Rv QALPAGGAMVAVQAAEEEVRPLLS----AEVDIAAVNGPASLVISGAQNA MAV_2450|M.avium_104 QALPEGGAMIAVQATEAQVRPLLG----PDVGIAAVNGPAAVVISGDHDA MLBr_00135|M.leprae_Br4923 QSMPAGGTMWAVAASEDEVVSLLG----EGVGIAAINAPESVVISGPQAA MAB_3148c|M.abscessus_ATCC_199 LRISGAGAMASVDLPAQQVVSELADRDIHDVVLAVVASPQSTVVGGATET TH_4621|M.thermoresistible__bu LRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPESTVIGGATDT :. .* * :: * * :.. .* *:.* Mflv_0405|M.gilvum_PYR-GCK LEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFESYAAQLQFAAPTL MSMEG_0408|M.smegmatis_MC2_155 LEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDEFEAYAAQFQFAAPTL Mvan_1003|M.vanbaalenii_PYR-1 LEQIVAGCSGEGIRTTWLDTSHAFHSALLDPVLDEFESCAARLAYAAPTR MMAR_3025|M.marinum_M VSAVAEQLRADGRRVHRLAVSHAFHSPLMDPMIDEFATVAGELTVNAPTI MUL_2266|M.ulcerans_Agy99 VSAVAEQLRADGRRVHRLAVSHAFHSPLMDPMIDEFATVAGELTVNAPTI Mb2074c|M.bovis_AF2122/97 VAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTI Rv2048c|M.tuberculosis_H37Rv VAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTI MAV_2450|M.avium_104 AVAIAERLRAEGHRVHRLSVSHAFHSPLMEPMIDEFGTVAAGLAIDKPVI MLBr_00135|M.leprae_Br4923 VSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEEFVRVAAQVEVRKPQI MAB_3148c|M.abscessus_ATCC_199 VRQLIAEWSDRGLMAREVAVDVASHSPQVDPILDDLADALEDLTPRTPVV TH_4621|M.thermoresistible__bu VRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILADLQPMTPTV : * : .. * ** ::*::::: . * Mflv_0405|M.gilvum_PYR-GCK PLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEI MSMEG_0408|M.smegmatis_MC2_155 PLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEI Mvan_1003|M.vanbaalenii_PYR-1 PLVCNRTGAVVTGPGVIDAQYWRRHARQPVQFAESVRTLADLGCSVLMEI MMAR_3025|M.marinum_M GIISNLTG-QLAGEDFGSAAYWKRHVRDAVRFADSIRFAQSAGAARFLEV MUL_2266|M.ulcerans_Agy99 GIISNLTG-QLAGEDFGSAAYWKRHVRDAVRFADSIRFAQSAGAARFLEV Mb2074c|M.bovis_AF2122/97 GVISNVTG-QLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEV Rv2048c|M.tuberculosis_H37Rv GVISNVTG-QLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEV MAV_2450|M.avium_104 PIISNLTG-QPAADDFGSPEYWKCHVRDAVRFADSVRFAQSAGATRFLEV MLBr_00135|M.leprae_Br4923 GLVSNVTG-ELAGPDFGSPQYWGEHVSRAVRFVDSARHLQTLGATHFIES MAB_3148c|M.abscessus_ATCC_199 PLYS-SVSFDPRERPIMDADYWVDNLRHTVRFAAAVQAALDDGYRVFGEL TH_4621|M.thermoresistible__bu PYYS-ATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAALEDGFRVFGEL . .. .. ** : *:*. : : * : * Mflv_0405|M.gilvum_PYR-GCK GPQPVLTGAAVQVWPEHLAAPR--AIASLRKGVADRRQIADALAAAYIGG MSMEG_0408|M.smegmatis_MC2_155 GPQPVLTGAAVQVWPEHMAAPR--AVASLRKGVADRRQIADALASAYVGG Mvan_1003|M.vanbaalenii_PYR-1 GPQPFLIAAALRVWPESAATPR--AIPSLRKGPDARRQLAEAVAAAYIAG MMAR_3025|M.marinum_M GPSSGLTASIEEVLSDAAVTNPVATASALRKDRPEPVSLVSAVAGVFVAG MUL_2266|M.ulcerans_Agy99 GPSIGLTASIEEVLSDAAVTNPVATASALRKDRPEPVSLVSALAGVFVAG Mb2074c|M.bovis_AF2122/97 GPSGGLVASIEESLPDVAVT----TMSALRKDRPEPATLTNAVAQGFVTG Rv2048c|M.tuberculosis_H37Rv GPSGGLVASIEESLPDVAVT----TMSALRKDRPEPATLTNAVAQGFVTG MAV_2450|M.avium_104 GPSSGLTAAIEETLADAPVV----TVSALRKDRPEPVALVNAVAQGWVCG MLBr_00135|M.leprae_Br4923 GPSSGLMGAIEQSLAPAEAV----VVSMMGKDRPELASVLGAAGQLFATG MAB_3148c|M.abscessus_ATCC_199 APHPLLVYPAEQTARSLDIP--MVALAGMRREQELPHGLRDFVGDLYTAG TH_4621|M.thermoresistible__bu SPHPLLTRAVEQTARGLDMP--VAALPAMRREQEMPHGVRTMVGDLFAAG .* * . . . . : : : . : * Mflv_0405|M.gilvum_PYR-GCK HKPDFAALHEQR-GVRLELPTYPFQRRRFWPK---SAGMAIDGRVGASAG MSMEG_0408|M.smegmatis_MC2_155 HRPDFAAVHRQP-RRPVELPTYPFQRRRFWPK---ASSIAVDG---GTAA Mvan_1003|M.vanbaalenii_PYR-1 HRLDFTGHDGGP-HRRLPLPTYPFQHRSYWPK---TAGIRSDG----SSG MMAR_3025|M.marinum_M TAVDWRAVVGQS--NFVELPTYAFERRRFWLS-GDAVAADAAGLGLQAGE MUL_2266|M.ulcerans_Agy99 TAVDWRAVVGQS--HFVELPTYAFERRRFWLS-GDAVPADAAGLGLQAGE Mb2074c|M.bovis_AF2122/97 MDLDWRAVVGEA--QFVELPTYAFQRRRFWLS-GDGVAADAASLGLAASE Rv2048c|M.tuberculosis_H37Rv MDLDWRAVVGEA--QFVELPTYAFQRRRFWLS-GDGVAADAAGLGLAASE MAV_2450|M.avium_104 MDVDWRGALGTG--HLVDLPTYAFDRRRFWLS-GDGAASDAAGLGLAAGD MLBr_00135|M.leprae_Br4923 MPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPGTDGTASVSGLGLGSTE MAB_3148c|M.abscessus_ATCC_199 GAVDFSVLYPTG--QLVDVPLPSWTRRSYLLD--LSAQAQQGHGTHTVAV TH_4621|M.thermoresistible__bu AAVDFAALYPSG--RLVDAPLPTWTRRKLVLS--RENGEQQTRGGCTITV :: : * .: :* Mflv_0405|M.gilvum_PYR-GCK SGILGSGKD-LASGD-SVYTSRLSVKTQPWLSDHVIYGTVVVPGATYAAM MSMEG_0408|M.smegmatis_MC2_155 SGILGSGKD-LASGD-TIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAM Mvan_1003|M.vanbaalenii_PYR-1 SGLLGSAQD-LASGD-IVHTSRLSVKTQPWLSDHVIYGTVVVPGATYAAM MMAR_3025|M.marinum_M HALLGAVVELPASGG-VVLTGRLSLAAQGWLADHAVGGVVIFPGAGFVEL MUL_2266|M.ulcerans_Agy99 HALLGAVVELPASGG-VVLTGRLSLAAQGWLADHAVGGVVIFPGAGFVEL Mb2074c|M.bovis_AF2122/97 HALLGAVIDLPASGG-VVLTGRLSPSVQGWLADHSVAGVTIFPGAGFVEL Rv2048c|M.tuberculosis_H37Rv HALLGAVIDLPASGG-VVLTGRLSPSVQGWLADHSVAGVTIFPGAGFVEL MAV_2450|M.avium_104 HALLGAVVELPASGG-VLLTGRLSPASQGWLADHAVGGVVLFPGAGFVEL MLBr_00135|M.leprae_Br4923 HALLGAVVERPDSGG-VVLTGRLSLANQPWLADHVIGGVVLFPGAGFVEL MAB_3148c|M.abscessus_ATCC_199 HPLLGAHVRLAEEPERHIWQADVGTVGQPWIADHQVRHVAVYPGAAYCEM TH_4621|M.thermoresistible__bu HPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAAYCEM :**: . : . :. * *::** : .. *** : : Mflv_0405|M.gilvum_PYR-GCK ALAAVGTP--AHAKDVFFYEPIILPEKSSREVQLTVHPSVDGESK-FQVH MSMEG_0408|M.smegmatis_MC2_155 ALAAVGTP--ARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIH Mvan_1003|M.vanbaalenii_PYR-1 ALAAMPTP--ARVQEVFFYEPIILGDKDSREVQLMLHRTDDADGWTFEVH MMAR_3025|M.marinum_M AIRAGDEVGCRVVDELTLAAPLVLPSGGSVAVQVVVGSPDDSGARAVSVY MUL_2266|M.ulcerans_Agy99 AIRAGDEVGCRVVDELTLAAPLVLPSGGSVAVQVVVGSPDDSGARAVSVY Mb2074c|M.bovis_AF2122/97 AIRAGDEVGCGVVDELTLAAPLVLPASGSVAVQVVVNGPDESGVRGVSVY Rv2048c|M.tuberculosis_H37Rv AIRAGDEVGCGVVDESTLAAPLVLPASGSVAVQVVVNGPDESGVRGVSVY MAV_2450|M.avium_104 AIRAGDEVGCGIIDELNLAAPLVLPAGGSVAIQVVVDGPDDSGARAVSVF MLBr_00135|M.leprae_Br4923 VIRAGDEVGCAGVEELVLAAPLVLHPGSGVQVQVVVAAADESSRRAVSVY MAB_3148c|M.abscessus_ATCC_199 ALSAAAAVFG-EGSAVQSISFEQLLTLGESTPISATATAKSADILEFVVE TH_4621|M.thermoresistible__bu ALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAVEPGTLEFAVE .: * : . . : Mflv_0405|M.gilvum_PYR-GCK SRPYGERGAE-WALNAEGVVASGVGDSPAAAGDLEDPVDE----AIERLN MSMEG_0408|M.smegmatis_MC2_155 SRPYGERGAD-WSLNAEGTVDTAGSDPDAAADEQSDPVDE----VIERLE Mvan_1003|M.vanbaalenii_PYR-1 SRPYGDRDAD-WSRNASGTVAAGVG--DAAPDAAADPVDN----AIERLT MMAR_3025|M.marinum_M SR--GDAGSD-WVLHAEGSLGSGSP--EPATDLSTWPPVG----AVE--- MUL_2266|M.ulcerans_Agy99 SR--GDAGSD-WVLHAEGSLGSGSP--EPATDLSTWPPVG----AVE--- Mb2074c|M.bovis_AF2122/97 SR--GDVGTG-WVLHAEGALRAGSA--EPTADLAMWPPAG----AVP--- Rv2048c|M.tuberculosis_H37Rv SR--GDVGTG-WVLHAEGALRAGSA--EPTADLAMWPPAG----AVP--- MAV_2450|M.avium_104 SR--ADAGAG-WLLHAEGVLRAGSA--QPATDLSAWPPVG----AVP--- MLBr_00135|M.leprae_Br4923 SR--GDQSHGGWLLNAEGLLEVDAA--EATVDLSLWPPEG----AES--- MAB_3148c|M.abscessus_ATCC_199 THDEGDVVKR-----ATAVLGNGGDVDMPIAYDLSALRAEHPHR------ TH_4621|M.thermoresistible__bu TAKDGEHERR-----ATAVLGAADDTEPPQAHDIDALLAEHPTR------ : .: * . : . Mflv_0405|M.gilvum_PYR-GCK RMRPQELFETFADLELAWGPTWSGSLKSLWLGEGE--AIGDILVGAELAE MSMEG_0408|M.smegmatis_MC2_155 RMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGE--AVGDILVGAELAE Mvan_1003|M.vanbaalenii_PYR-1 RTRPQQLFDAFADNDLAWGPAWCSSLRSLWVGTGE--AVGDIAVGAELGE MMAR_3025|M.marinum_M -VENADGYQQLAERGYGYGPAFRG-LNAMWRRGDE--VFAEVALPADAGV MUL_2266|M.ulcerans_Agy99 -VENADGYQQLAERGYGYGPAFRG-LNAMWRRGDE--VFAEVALPADAGV Mb2074c|M.bovis_AF2122/97 -VEVADGYQQLAERGYGYGPAFRG-LTAMWRRGDE--VFAEVALPADAGV Rv2048c|M.tuberculosis_H37Rv -VEVADGYQQLAERGYGYGPAFRG-LTAMWRRGDE--VFAEVALPADAGV MAV_2450|M.avium_104 -VDLGDGYEQLAERGYRYGPAFRG-LTSMWRRGDE--IFAEVNLPTDAGV MLBr_00135|M.leprae_Br4923 -VDISDAYPQLAERGYAYGPAFQG-LVAIWRRGSE--LFAEVVAPT--GV MAB_3148c|M.abscessus_ATCC_199 -ESGDDLRASFDERGVQYGPAFQGLAAAYRGDETVRSVLAEVTLPRDVRA TH_4621|M.thermoresistible__bu -IEGDELRQWFDQRGVQFGPAFTGLTAARIPEGTVTSVLAEVGLPGQIRS : : : :**:: . : ..:: Mflv_0405|M.gilvum_PYR-GCK QLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYGQVSLQEK MSMEG_0408|M.smegmatis_MC2_155 QLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLAEK Mvan_1003|M.vanbaalenii_PYR-1 HLGREPIHPVLLDLCTGIAGAALLAAAAQTDADPELFLPLRYGRVEVRER MMAR_3025|M.marinum_M SVSGFGIHPVMLDAALHAVILASDGADDFGVPEGSVLVPFAWQGVTLHAA MUL_2266|M.ulcerans_Agy99 SVSGFGIHPVMLDAALHAVILASDGADDFGVPEGSVLVPFAWQGVTLHAA Mb2074c|M.bovis_AF2122/97 SVTGFGVHPVLLDAALHAVVLSAESAERG---QGSVLVPFSWQGVSLHAA Rv2048c|M.tuberculosis_H37Rv SVTGFGVHPVLLDAALHAVVLSAESAERG---QGSVLVPFSWQGVSLHAA MAV_2450|M.avium_104 STTGFGVHPVMLDAALHAVMLASDGDDLP---AGSMLVPFSWQRVSLHAA MLBr_00135|M.leprae_Br4923 VVDGMGMHPALLDAVLHALGLAIENTQAT----TEMRLPFCWRGVSLHAG MAB_3148c|M.abscessus_ATCC_199 QQGSYIVHPALLDACFQSVIALPDVQEASK---DALPLPKGVRSLHAYES TH_4621|M.thermoresistible__bu QQAPYGIHPALLDACFQSVAAHPDVQGAG----SGLLLPLGVRRLQAFGP :**.::* : :* : Mflv_0405|M.gilvum_PYR-GCK MPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVREFTVKRAPREA MSMEG_0408|M.smegmatis_MC2_155 MPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREA Mvan_1003|M.vanbaalenii_PYR-1 MPRRFYCRARWQTGGIDSETQVFDLDFLDHDGRNLGGIREFTVKRAPREA MMAR_3025|M.marinum_M GASAVRARIAPAG------PSAVSIELSDGLGLPVLSVASMLARPVTDQQ MUL_2266|M.ulcerans_Agy99 GASAVRARIAPAG------PSAVSIELSDGLGLPVLSVASMLARPVTDQQ Mb2074c|M.bovis_AF2122/97 GASAVRARIAPVG------PSAVSIELADGLGLPVLSVASMLARPVTDQQ Rv2048c|M.tuberculosis_H37Rv GASAVRARIAPVG------PSAVSIELADGLGLPVLSVASMLARPVTDQQ MAV_2450|M.avium_104 GAAAVRARIVPVS------PSAVSIELADGLGLPVLSVASMVARPVTDQQ MLBr_00135|M.leprae_Br4923 GAGRVRARFTSAG------ADAIAVDIADSAGLPVLTVRSLVTRAMTAEQ MAB_3148c|M.abscessus_ATCC_199 ARATQYCYTRVTKVV--GNEVEADIDLLDETGSVLIAVRGFRFGTGSSDD TH_4621|M.thermoresistible__bu TRGARYCYARVTDAD--GSKAEADLDVLDEHGNVLLRVQGLLMGGAAADG . :: * * : : : . : Mflv_0405|M.gilvum_PYR-GCK LLRGLGGDA---TRLLYTLGWHEVPVPESGDGAAP-QGTWLIGGFDELAV MSMEG_0408|M.smegmatis_MC2_155 LLRGLGGDA---TRLLYTLGWHEVPPPPSADDAV---GTWLIAGFDELAA Mvan_1003|M.vanbaalenii_PYR-1 LLRGLGADA---TRLIYRVGWRETSPPVRDDGALGPSSTWLVAGLDALAD MMAR_3025|M.marinum_M LRAAVSGAG---PDRLFGVDWTAQPSAELQP--------VPVRIWGAVES MUL_2266|M.ulcerans_Agy99 LRAAVSGAG---PDRLFGVDWTAQPSAELQP--------VPVRIWGTVES Mb2074c|M.bovis_AF2122/97 LRAAVSSSG---PDRLFEVTWSPQPSAAVEP--------LPVCAWGTTED Rv2048c|M.tuberculosis_H37Rv LRAAVSSSG---PDRLFEVTWSPQPSAAVEP--------LPVCAWGTTED MAV_2450|M.avium_104 LLAAVSNSG---PDRLFELIWSAQPSTAVQP--------VSLLNWGATEL MLBr_00135|M.leprae_Br4923 LRTAVTAAGGALEQGPMDLVWSPIPLSSDGHGGGL----PSVVSWADYCA MAB_3148c|M.abscessus_ATCC_199 EQRDQLLNN-----RLLAIEWQQQRLPESVSGAPRRWLLVSTGESVDPWA TH_4621|M.thermoresistible__bu DDRDRVLGE-----RLLTIEWQRRDLPEADS-AAGKWLLVSTSATADVSA : * . Mflv_0405|M.gilvum_PYR-GCK SVPGCIPADR----------------TNPESLRQLLTDAHGRGLPFSGVV MSMEG_0408|M.smegmatis_MC2_155 KVPGCVPIDRN---------------TDLQVLGEVLSQAHARGAGFSGVV Mvan_1003|M.vanbaalenii_PYR-1 DVPGSIRIGFDRIWDPDRDGRVVLDPADDEHWRRLFALADERRAPVAGVV MMAR_3025|M.marinum_M EGDDDPG---------------------------------------ASVV MUL_2266|M.ulcerans_Agy99 EGDDDPG---------------------------------------ASVV Mb2074c|M.bovis_AF2122/97 S---------------------------------------------AAVV Rv2048c|M.tuberculosis_H37Rv S---------------------------------------------AAVV MAV_2450|M.avium_104 DATDTDSDSGR-----------------------------------FAVL MLBr_00135|M.leprae_Br4923 GRGNDTG----------------------------------------VVV MAB_3148c|M.abscessus_ATCC_199 AELIDSLKVRES---------EVSLIQWRPNTDRVAALKLLYDQLESGTF TH_4621|M.thermoresistible__bu TRLSDALKQAGA---------ESTSMCWPQQADHADNVDRFRAGIADG-V . Mflv_0405|M.gilvum_PYR-GCK WRAARSDGDESD--AEVAARLEAEIAELLGAVHTVQGGEVKLPGGLWIVT MSMEG_0408|M.smegmatis_MC2_155 WRCATPGRKESGSASAESARLEAEITNLLSAVHAAQGPSVKLPGGLWIVT Mvan_1003|M.vanbaalenii_PYR-1 LGVTGRARPEEPS-ADFAARLEAQIRDVLGAVHSLSALGAKPAAGLWIVT MMAR_3025|M.marinum_M FESVPQAG-------EVVAGVYAATAAVLEVLRSWLSR--DGAGQLVITT MUL_2266|M.ulcerans_Agy99 FESVPQAG-------EVVAGVYAATAAVLEVLRSWLSR--DGAGQLIITT Mb2074c|M.bovis_AF2122/97 FESVPLAG-------DVVAGVYAATSSVLDVLQSWLTR--DGAGVLVVMT Rv2048c|M.tuberculosis_H37Rv FESVPLAG-------DVVAGVYAATSSVLDVLQSWLTR--DGAGVLVVMT MAV_2450|M.avium_104 FESAPVAG-------DVVTEVYAATRAVLPVLQSWLAR--DGAGTLVVST MLBr_00135|M.leprae_Br4923 WEFGSASAGAQAP-VDSVAAVYSATHAALQVLQFWFGQ--DRAGTLVVLT MAB_3148c|M.abscessus_ATCC_199 DGVLVVTAPGSEGGADRVVLQGADQVRHLVRITRELVDLPGEPPRLFVVT TH_4621|M.thermoresistible__bu TGVVVLTGPKNGNPDDAAARRGSDYVRHLVRITRELAEIDGDAPRLFVVT . : * : . * : * Mflv_0405|M.gilvum_PYR-GCK ERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLVDCDGSPQAVQAL MSMEG_0408|M.smegmatis_MC2_155 EHGVACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDLL Mvan_1003|M.vanbaalenii_PYR-1 ERAVAAEAGEPVDPVQSALWGLGRTLIAEEPGLRCLLVDLDGSEDAGPAL MMAR_3025|M.marinum_M RGAVALPDEDVTDLAGSAVWGLVRSAQTEHPG-RIVLVDTD-AQLDEHAV MUL_2266|M.ulcerans_Agy99 RGAVALPDEDVTDLAGSAVWGLVRSAQTEHPG-RIVLVDTD-AQLDEHAV Mb2074c|M.bovis_AF2122/97 RGAVALPGEDVTDLAGAAVWGLVRSAQTEHPG-RIVLVDSD-APLDDSAL Rv2048c|M.tuberculosis_H37Rv RGAVALPGEDVTDLAGAAVWGLVRSAQTEHPG-RIVLVDSD-APLDDSAL MAV_2450|M.avium_104 RGAMTLPGEDVTDLAGAAVWGLVRSAQTEHPG-RIVLVDTD-APLDADAV MLBr_00135|M.leprae_Br4923 RGAVGLVGEGISDLAAAAVWGMVRSAQSEHSG-KIVLIDTD-SAVD---V MAB_3148c|M.abscessus_ATCC_199 RNAQTVVDGDITNLEQAGLRGLVRVIGAEYPHLRVTHIDVDRHTAAQNVA TH_4621|M.thermoresistible__bu RGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIADDADLDRVA . . : :.: *: * * . : :* Mflv_0405|M.gilvum_PYR-GCK AALLSTP-VDEPELAVRQGKLLASRLLPWSRSGH----LTVPRG-GDYVL MSMEG_0408|M.smegmatis_MC2_155 AALLAAPGIQEPEIAVRQGKLLASRLLPWARSGH----LTLPRG-GDFVL Mvan_1003|M.vanbaalenii_PYR-1 ARLLGAP-GDEPELALRQGRLLVPRLLPWSRSGQ----LAIPRG-TDYVL MMAR_3025|M.marinum_M AAVLAAG---EPQVLWRNGEVYTARVHGSRAVAG----LLVPPGDGPWRL MUL_2266|M.ulcerans_Agy99 AAVLAAG---EPQVLWRNGEVYTARVHGSRAVAG----LLVPPGDGPWRL Mb2074c|M.bovis_AF2122/97 AAVVTTG---EPQVLWRRGEVYTARVHGSRAVGG----LLVPPSDRPWRL Rv2048c|M.tuberculosis_H37Rv AAVVTTG---EPQVLWRRGEVYTARVHGSRAVGG----LLVPPSDRPWRL MAV_2450|M.avium_104 AAVLAVG---EPQTLLRNGTVYTARVLGSRAVGA----LLVPPEDGPWRL MLBr_00135|M.leprae_Br4923 AVLADLG---ESQLLVRCNTVHAARLS--PAPQL----LALPVGESMWRL MAB_3148c|M.abscessus_ATCC_199 GELVSGS--EEDETAWREDHWYRARLNLGPLGPDDWRSTVATPNNEGVRF TH_4621|M.thermoresistible__bu VQLLGGG--AEDETAWRDGQWYTARLSLSPLRPEERKQAVVDCERDGMRL : * : * . .*: : Mflv_0405|M.gilvum_PYR-GCK APTERGAIDNLRLTDS-EVPPPAE-GYVQVRVEAAGLNFRDVLNVLGLYP MSMEG_0408|M.smegmatis_MC2_155 APTERGAIDNLRLTET-DVPEPDE-GYVQVRVEAAGLNFRDVLNVLGLYP Mvan_1003|M.vanbaalenii_PYR-1 APTERGVLDNLRVSET-EVTAPPE-GHVQVRVEAAGLNFRDVLNALGLYP MMAR_3025|M.marinum_M GMSTAGTFENLRLEPIPDADAALQPGHVRVALSAMAANFRDVMIALGLYP MUL_2266|M.ulcerans_Agy99 GMSTAGTFENLRLEPIPDADAALQPGHVRVALSAMAANFRDVMIALGLYP Mb2074c|M.bovis_AF2122/97 AMSTAGTFENLRLELIPDADAPLGPGQVRVAVSAIAANFRDVMIALGLYP Rv2048c|M.tuberculosis_H37Rv AMSTAGTFENLRLELIPDADAPLGPGQVRVAVSAIAANFRDVMIALGLYP MAV_2450|M.avium_104 GMSSYGTIENLRLEPIPDADAPLGPGQVRVATSALAANFRDVMIALGLYP MLBr_00135|M.leprae_Br4923 AADGGGTLEDLVIQPCPEVQAPLQAGHMRVAVAAVGVNFRDVVAALGMYP MAB_3148c|M.abscessus_ATCC_199 EVRTPGDLQSLGFVAFDRVAPGPG--QIEVSVTATSINFADVLNVYGRYS TH_4621|M.thermoresistible__bu EIRTPGDLETMELAAFDRVPPGPG--QIEVAVTASSINFADVLIAFGRYP * :: : . . :.* * . ** **: . * *. Mflv_0405|M.gilvum_PYR-GCK ---GDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQGAFA-SRFNVPG MSMEG_0408|M.smegmatis_MC2_155 ---GDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFA-SRFNVPA Mvan_1003|M.vanbaalenii_PYR-1 ---GDPGPIGGELAGVVTAPGPDVDGFDVGQRVFGFAVGAFA-SRVNVPV MMAR_3025|M.marinum_M ---DPDAAMGVEGAGVVVETASTDGRFAVGDRVVGLFPEGTG-TIAITDH MUL_2266|M.ulcerans_Agy99 ---DPDAAMGVEGAGVVVETASPDGRFAVGDRVVGLFPEGTG-TIAITDH Mb2074c|M.bovis_AF2122/97 ---DPDAVMGVEACGVVIETSLNKGSFAVGDRVMGLFPEGTG-TVASTDQ Rv2048c|M.tuberculosis_H37Rv ---DPDAVMGVEACGVVIETSLNKGSFAVGDRVMGLFPEGTG-TVASTDQ MAV_2450|M.avium_104 ---DPDAVMGIEASGVVIETASQDGRVAVGDRVMGLFPDGTG-TVATTDQ MLBr_00135|M.leprae_Br4923 ---GQAPPLGAEGAGVVIEIGPEVTGVAVGDAVMG-FLGGAG-PLAVVHQ MAB_3148c|M.abscessus_ATCC_199 SFEGRQ-ELGVDFAGVVTAVGEGVTQHQVGDRVGGMTPTGAWRSFVVVDA TH_4621|M.thermoresistible__bu TFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGCWSTFVTCDA . :* : .*.* . :*: * * . . Mflv_0405|M.gilvum_PYR-GCK QFLAPIPDGVSAVEAATIPAAALTVRLSF-DWAQVKSGDKVLIHAASGGV MSMEG_0408|M.smegmatis_MC2_155 QFLAPIPDGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKVLIHAASGGV Mvan_1003|M.vanbaalenii_PYR-1 QFLAPVPEGISAVAAATTPAAVLTAGLAF-DWAALRAGDRVLIHAASGGV MMAR_3025|M.marinum_M RLLVKIPAGWSDTAAATTSVVFATAFYALRDLASVQPGQRILVHAATGGV MUL_2266|M.ulcerans_Agy99 RLLVKIPAGWSDTAAATTSVVFATAFYALRDLASVQPGQRILVHAATGGV Mb2074c|M.bovis_AF2122/97 RLLVKVPAGWSHTAAATTSVVFATAHYALVDLADVQPGQRVLIHAGTGGV Rv2048c|M.tuberculosis_H37Rv RLLVKVPAGWSHTAAATTSVVFATAHYALVDLAAARSGQRVLIHAGTGGV MAV_2450|M.avium_104 RLLVKVPAGWSHTAAATASVVFATAYYALVDLADARPGQRVLVHAAAGGV MLBr_00135|M.leprae_Br4923 QLITQMPQGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLIHAGTGGV MAB_3148c|M.abscessus_ATCC_199 NLAATLPAEVPDREAAAVPGAHVTAWYGLHELARISAGDKVLIHSGTGGV TH_4621|M.thermoresistible__bu DLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLIHSATGGV : . :* **: . . *. .: : * .*: :*:*:.:*** Mflv_0405|M.gilvum_PYR-GCK GLAAVQMAQQCGAEVYATAST-FKRATLRKLG--VKHVYDSRTTDFAEQI MSMEG_0408|M.smegmatis_MC2_155 GLAAIQMAQQSGAEVFATAST-FKRSTLRRLG--VKYVYDSRTTDFADQI Mvan_1003|M.vanbaalenii_PYR-1 GLAAVQLARQRGATVFATASG-YKRPMLRAMG--VDHVYDSRTTDFADQI MMAR_3025|M.marinum_M GMAAVQLARHWGLEVFATASK-GKWDTLRAMGFDEDHIGDSRSLEFEDKF MUL_2266|M.ulcerans_Agy99 GMAAVQLARHWGLEVFATASK-GKWDTLRAMGFDEDHIGDSRSLEFEDKF Mb2074c|M.bovis_AF2122/97 GMAAVQLARHLGLEVFATASK-GKWDTLRAMGFDDDHISDSRSLEFEDKF Rv2048c|M.tuberculosis_H37Rv GMAAVQLARHLGLEVFATASK-GKWDTLRAMGFDDDHISDSRSLEFEDKF MAV_2450|M.avium_104 GMAAVQLARHLGLEVFATASR-GKWDTLRDMGFDDDHLGDSRGLDFEDKF MLBr_00135|M.leprae_Br4923 GMAAVQFARHWGVEIFVTASR-GKWDTLRDMGFDDDHIGDSRTLEFEEKF MAB_3148c|M.abscessus_ATCC_199 GQAAIAIARAAGAEIYATAGSPERRDLLRSWG--IKHVYDSRSTDFAELI TH_4621|M.thermoresistible__bu GLAAIAIARSVGAQIYATAGSPARRDLLRDMG--IEHVYDSRSTAFADEI * **: :*: * ::.**. : ** * .:: *** * : : Mflv_0405|M.gilvum_PYR-GCK LADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDIW--TVEQ MSMEG_0408|M.smegmatis_MC2_155 LADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIW--SHEQ Mvan_1003|M.vanbaalenii_PYR-1 LADTDGAGVDVVLNSLTNDGFVAATVRATARNGRFAEIAKRDIW--SPEQ MMAR_3025|M.marinum_M RAATGGRGMDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDIR--EAAV MUL_2266|M.ulcerans_Agy99 RAATGGRGMDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDIR--EAAV Mb2074c|M.bovis_AF2122/97 RAATGGRGFDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDIR--DPGV Rv2048c|M.tuberculosis_H37Rv RAATGGRGFDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDIR--DPGV MAV_2450|M.avium_104 RAVTGGAGMDIVLDSLSGD-SVDASLRLVAPGGIFLEMGKTDIR--DPEV MLBr_00135|M.leprae_Br4923 LAVTDGRGVDVVLDSLAGD-FVDASLRLLVRGGRFLEMGKTDIR--DAQE MAB_3148c|M.abscessus_ATCC_199 RRDTDGYGVDIVLNSLTGA-AQRAGVELLTFGGRFIEIGKRDIYGDTRLG TH_4621|M.thermoresistible__bu RRDTDGYGVDVVLNSLPGA-AQRAGLELLSFGGRFIEIGKRDIYGDTRLG *.* *.*:**:**.. * :. * * *:.* ** Mflv_0405|M.gilvum_PYR-GCK MAAARPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDGAWTPLPAEVY MSMEG_0408|M.smegmatis_MC2_155 MAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIY Mvan_1003|M.vanbaalenii_PYR-1 MAAARPDIDYEVLALDAVMQQDPDRIQLLLADLADSLARGETAPLPFEAY MMAR_3025|M.marinum_M VAQQHTGVRYRAFDLFEAG---PDHIAQILAELAALFSEDALRPLPVTTF MUL_2266|M.ulcerans_Agy99 VAQQHTGVRYRAFDLFEAG---PDHIAQILAELAALFSEDVLRPLPVTTF Mb2074c|M.bovis_AF2122/97 IAQQYPGVRYRAFDLFEAG---PDRIAQILAELATLFGDGVLRPLPVTTF Rv2048c|M.tuberculosis_H37Rv IAQQYPGVRYRAFDLFEPG---PDRIAQILAELATLFGDGVLRPLPVTTF MAV_2450|M.avium_104 VAAEHPGVRYRAFDLFEAG---PDRIARLLDELAAMFGEDVLRPLPVTRF MLBr_00135|M.leprae_Br4923 IAANYPGVQYRAFDLSEAG---PVRMQEMLCEVRELFDTQVLHRLPVTSW MAB_3148c|M.abscessus_ATCC_199 LFPFRRNLSFHAVDLVLVAKTRPEAIYRTLTALYGQMAEGVLPLPEISPS TH_4621|M.thermoresistible__bu LFPFRRNLAFHGVDLGLMADSHPHKIRELLETVYRLTADGVLPMPQSTHY : .: :. . * * : * : Mflv_0405|M.gilvum_PYR-GCK PLTEARAAFRRMQQARHIGKIVVQIPNP------------LQPQPDRSYL MSMEG_0408|M.smegmatis_MC2_155 PITEARSAFRRMQQARHIGKIVLQVPKP------------LQPQQDRSYL Mvan_1003|M.vanbaalenii_PYR-1 PLAEATTAFRRMQQARHTGKIILQMPKP------------LQPHGDRSYL MMAR_3025|M.marinum_M DVRRAPAALRYLSQARHVGKVVLTMP---------------DAWAAGTVL MUL_2266|M.ulcerans_Agy99 DVRRAPAALRYLSQARHVGKVVLTMP---------------DAWAAGTVL Mb2074c|M.bovis_AF2122/97 DVRRAPAALRYLSQARHTGKVVMLMP---------------GSWAAGTVL Rv2048c|M.tuberculosis_H37Rv DVRCAPAALRYLSQARHTGKVVMLMP---------------GSWAAGTVL MAV_2450|M.avium_104 DVRRAPAALRYLSQARHVGKVVMTMP---------------DAWTAGTVL MLBr_00135|M.leprae_Br4923 DVRCAPAAFRFMSQARHIGKVVLTMPSA-----------LADGLAEGTVL MAB_3148c|M.abscessus_ATCC_199 PLQEAAESIRVMGAAGHTGKLVLDLPKAGEVSAVIPPSHAPAFRRDGAYV TH_4621|M.thermoresistible__bu PLAEAATAIRVMSAAEHVGKLVLDVPHTGRADVVVPPEQASPFRSDGAYI : * ::* : * * **::: :* : : Mflv_0405|M.gilvum_PYR-GCK ITGGLGAIG-LHTAGYLAQLGAGDIVLTSRRAPDAAAQQAIADIADRTKA MSMEG_0408|M.smegmatis_MC2_155 ITGGLGAIG-LHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKC Mvan_1003|M.vanbaalenii_PYR-1 ITGGLGALG-LHAAAYLAQLGAGDIVLTGRRMPDAATERAISEIAERYHC MMAR_3025|M.marinum_M ITGGTGMAGSALARHVVAHHGVRQLVLVSRRGPDAPGAAELAEELSAFGA MUL_2266|M.ulcerans_Agy99 ITGGTGMAGSALARHVVAHHGVRQLVLVSRRGPDAPGAAELAEELSAFGA Mb2074c|M.bovis_AF2122/97 ITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGA Rv2048c|M.tuberculosis_H37Rv ITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGA MAV_2450|M.avium_104 ITGATGMAGSAVARHVVTRHGARNLVLVSRRGLDAPDAAELVAELTAAGA MLBr_00135|M.leprae_Br4923 ITGASGAIGGVLARHMVSAYGVRHLVLASRRGDRAEGAVELAAELVGAGA MAB_3148c|M.abscessus_ATCC_199 VTGGLGGLG-LFLARKLAAAGVGRIILNGRSAPKPEALAAIEQIRQGGTE TH_4621|M.thermoresistible__bu VTGGMGGLG-LYLAGEMAAAGAGCIVLNGRSAPSGEALRTIEQLRAAGTE :**. * * :: *. ::* .* : Mflv_0405|M.gilvum_PYR-GCK RLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQQSVE MSMEG_0408|M.smegmatis_MC2_155 RIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPE Mvan_1003|M.vanbaalenii_PYR-1 RIHTFAADVGDESAVRDLLERIRTELPPLAGVAHLAGVLDDALLPQQSPE MMAR_3025|M.marinum_M QVQVVACDAADRAALAKLIADIPVQHP-LSAVIHTAGALDDAVVTSLTPE MUL_2266|M.ulcerans_Agy99 QVQVVACDAADRAALAKLIADIPMQHP-LSAVIHTAGALDDAVVTSLTPE Mb2074c|M.bovis_AF2122/97 QVQVVACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPD Rv2048c|M.tuberculosis_H37Rv QVQVVACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPD MAV_2450|M.avium_104 HAEVVACDAADREALAKVIADIPMQHP-LTGVIHAAGVLDDAVVTSLTPQ MLBr_00135|M.leprae_Br4923 KIQVVACDVADNDAVRGLFAQLSREFPPVRGVIHAAGVLDDGAITSLTPD MAB_3148c|M.abscessus_ATCC_199 IDVALGDIAEPDTAQRLVAAATETGKPVRGVLHAAALVHDATLANITDEL TH_4621|M.thermoresistible__bu VIVECGXX----XRGQPVEVAVPT------ELRHADEHPDRRGAQLCDEF : : * Mflv_0405|M.gilvum_PYR-GCK RFRTALAPKAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSPGQSNYATAN MSMEG_0408|M.smegmatis_MC2_155 RFRTTLAPKAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANYATAN Mvan_1003|M.vanbaalenii_PYR-1 RFRTTLAPKAFGAWHLHRLTRDTELEFFIVYSSGSSVLGSPGQANYATAN MMAR_3025|M.marinum_M RMETVLRAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQGNYAAAN MUL_2266|M.ulcerans_Agy99 RIETVLRAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQGNYAAAN Mb2074c|M.bovis_AF2122/97 RVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAAAN Rv2048c|M.tuberculosis_H37Rv RVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAAAN MAV_2450|M.avium_104 RIDTVLRAKVDAAWNLHELTRDLDVGAFVMFSSIAGLAGASGQGNYAAGN MLBr_00135|M.leprae_Br4923 RVDTVLRAKVDAAWNLHEATRDLDLLMFVLCSSIAATVGSPGQGNYSAAN MAB_3148c|M.abscessus_ATCC_199 IDRGDWRPKVHGAWNLHEATADQPLDWFCSFSSIAALVGSPGQGAYAAAN TH_4621|M.thermoresistible__bu A-----RGEQGAQRNQHRTDAGEGQRDAHPPGAVGHDQPDPG----ALSD : . : .. .: . .* : .: Mflv_0405|M.gilvum_PYR-GCK AFLDGLVAQRRAQGLPATGVNFGPWARGGMASSEAAAANIS---AQGLIP MSMEG_0408|M.smegmatis_MC2_155 AMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANIT---AQGLIP Mvan_1003|M.vanbaalenii_PYR-1 AVLDGLVAHRKARGLPATGVNWGPWAQGGMATSDAARANLG---AQGLIP MMAR_3025|M.marinum_M SFLDGLAVHRQAHGLPAISLGWGLWDQASNMTGGLAAVDFKRFARDGIVA MUL_2266|M.ulcerans_Agy99 SFLDGLAVHRQAHGLPAISLGWGLWDQASNMTGGLAAVDFKRFARDGIVA Mb2074c|M.bovis_AF2122/97 SFLDALAAHRRAHGLPAISLGWGLWDQASAMTSGLATVDFKRFARDGIVA Rv2048c|M.tuberculosis_H37Rv SFLDALAAHRRAHGLPAISLGWGLWDQASAMTGGLATVDFKRFARDGIVA MAV_2450|M.avium_104 SFLDGLAAHRRAHGLPAISLGWGLWDQASAMTGGLGAADLARFGRDGIVA MLBr_00135|M.leprae_Br4923 AFLDGLAAYRQAAGLAGTSLAWGLWEQPGGMNAHLSSRDLARISRSGLAP MAB_3148c|M.abscessus_ATCC_199 SWLDGFTHWRRAQGLPATVIAWGAWSEIGQGTHLAQNAEAA--------- TH_4621|M.thermoresistible__bu TGLD----ERGGQFPGVGVQIPVADPGVGIDHRGAVRVDSG--------- : ** * . . : Mflv_0405|M.gilvum_PYR-GCK LEPSAALTAMAEVVANGTAQATVLKANWQR-AAKVLGSSRPPILDLVLPS MSMEG_0408|M.smegmatis_MC2_155 LDPSAALHALAEVIANGSGQATVLKANWQR-AAKVLGSARPPILDLVLPS Mvan_1003|M.vanbaalenii_PYR-1 LEPTAALNALGEIVAHGIASAVVLKANWQR-AAKLLGATRPPILDHVLPS MMAR_3025|M.marinum_M MSSDEALGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMFVDLINA MUL_2266|M.ulcerans_Agy99 MSSDEALGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMFVDLINA Mb2074c|M.bovis_AF2122/97 MSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMFVDLINA Rv2048c|M.tuberculosis_H37Rv MSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMFVDLINA MAV_2450|M.avium_104 MSSQEALELMDTALIVDEPFLLPAHIDLAALRVKFDGGTLPPMFVDLINA MLBr_00135|M.leprae_Br4923 MNPAQALELFDAALVIDHPFMVTALLDRAALDAQAQAGALPPLFSRLVRR MAB_3148c|M.abscessus_ATCC_199 ILPDEGAYAFDTVLRHNRAYTAYAPMAGISWLADFVERSPFAQAFRDAGQ TH_4621|M.thermoresistible__bu VPAQQGVDG--EVVRH-RTLSSVRSGRSSRWTAP---GSRCGSGRRYGGE : . . : . : Mflv_0405|M.gilvum_PYR-GCK AVGEITGDS--------ELLKQLQEIPVPQRAGFVTEFLQKEVQNFLRLA MSMEG_0408|M.smegmatis_MC2_155 AAGEATGDS--------ELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLA Mvan_1003|M.vanbaalenii_PYR-1 AVAAGPGDS--------ALLKQLQDVPEAQRGSFVTEHLQRELQQILGLA MMAR_3025|M.marinum_M PTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIATVLGNS MUL_2266|M.ulcerans_Agy99 PTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIATVLGNS Mb2074c|M.bovis_AF2122/97 PTRRQVDDSLAAAKSKSALAHRLHGLPEDEQHAVLLDLVRSHIATVLGSA Rv2048c|M.tuberculosis_H37Rv PTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAVLLDLVRSHIATVLGSA MAV_2450|M.avium_104 PTRRQVDDSLAAAKSKSALLQRLEGLPEDEQQAVLLDLVRSNIATVLGSS MLBr_00135|M.leprae_Br4923 SRRRQIEDPGDATQSKLALVQRLQGLAANRQLELLVGVVCLQAAAVLGRP MAB_3148c|M.abscessus_ATCC_199 NQTET---------------NKFLDELRALPREEWPTRLRKLVAEQVGLV TH_4621|M.thermoresistible__bu S------------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK QPPAATS--RFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIG MSMEG_0408|M.smegmatis_MC2_155 SPPAASS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIG Mvan_1003|M.vanbaalenii_PYR-1 QPPAATG--RFLELGMDSLMAVELRNRLVGQFGSGFTITATAVFDYPTIG MMAR_3025|M.marinum_M SPDAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPNSA MUL_2266|M.ulcerans_Agy99 SPDAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPNSA Mb2074c|M.bovis_AF2122/97 SPEAIDPDRAFQDLGFDSLTAVEMRNRLKSATG--LSLSPTLIFDYPNSA Rv2048c|M.tuberculosis_H37Rv SPEAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPNSA MAV_2450|M.avium_104 SPEAIHPDRAFQELGFDSLTAVEMRNRLKAATG--LALSPTLIFDYPNSA MLBr_00135|M.leprae_Br4923 SPEDIDPNTKFQDLGFDSLTAVELRNRLKSATG--LTLPPTVIFDHPTPT MAB_3148c|M.abscessus_ATCC_199 LRRSIDPDRSLPDYGLDSLGNLEIRTRIQADTGVRIGPADVSTVRSLAAH TH_4621|M.thermoresistible__bu CRRTTGP----------AAGAAARRGRTRRRRRPRRPPPPPDRVRHRAGP : * * . Mflv_0405|M.gilvum_PYR-GCK GLAEYLVAQLPDAETP---------------------------------- MSMEG_0408|M.smegmatis_MC2_155 GLAEYLVGQLPDAEAP---------------------------------- Mvan_1003|M.vanbaalenii_PYR-1 ALAEYLAAQTPESTEE---------------------------------- MMAR_3025|M.marinum_M ALAGYMHRELVGASPQSDITAEAPGEAELQRVVASIPVKRLRQAGVLELL MUL_2266|M.ulcerans_Agy99 ALAGYMHRELVGASPQSDTTAEAPGEAELQRVVASIPVKRLRQAGVLELL Mb2074c|M.bovis_AF2122/97 ALAGYMRRELLGSSPQ-DTSAVAAGEAELQRIVASIPVKRLRQAGVLDLL Rv2048c|M.tuberculosis_H37Rv ALAGYMRRELLGSSPQ-DTSAVAAGEAELQRIVASIPVKRLRQAGVLDLL MAV_2450|M.avium_104 ALAGYMYRELVGTSEQ-PTAAAAPGEAEIQRVVGSIPVKRLRQAGVLELL MLBr_00135|M.leprae_Br4923 AVAEYVAQQMLKSRPA---------------------------------- MAB_3148c|M.abscessus_ATCC_199 IYDRLAEQESEVASS----------------------------------- TH_4621|M.thermoresistible__bu AHGPVRR------------------------------------------- Mflv_0405|M.gilvum_PYR-GCK -----QAAPQSESEPGPDVTE---------------------- MSMEG_0408|M.smegmatis_MC2_155 -----ETA----------------------------------- Mvan_1003|M.vanbaalenii_PYR-1 -----GTEMKTADPDGQPATVGHADVVLQTS------------ MMAR_3025|M.marinum_M LALANETGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE- MUL_2266|M.ulcerans_Agy99 LALANETGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE- Mb2074c|M.bovis_AF2122/97 LALANETETSGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE- Rv2048c|M.tuberculosis_H37Rv LALANETETSGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE- MAV_2450|M.avium_104 LALANESTGTAQSATPAVTTEKDIADMDLDDLVNAALLDDDDE MLBr_00135|M.leprae_Br4923 -----ESGDETSQAVEPKVEEVSVHA----------------- MAB_3148c|M.abscessus_ATCC_199 ------------------------------------------- TH_4621|M.thermoresistible__bu -------------------------------------------