For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_3025 (pks12)

annotation: polyketide synthase, Pks12
coordinates: 3649476 - 3662039
length: 4187

VDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGVDSPEGLWQMVAEGRDVMSDFP
TDRGWDLADLFDPDPDTPHKSYASTGGFVDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGI
DPTGLRGSATGVFAGLIVQGYGMFAEEIEGYRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALH
MAVQSLRSGECDLALAGGATVNATPTVFVEFSRHRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDA
QRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQ
ALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVLPATLHVDVPSPHVDWSA
GAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVVSAKSGSA
LGAQAARLAAHVRSHDELDVADVGWSLAGRSTFEHRAVVLGVDRDGLLAGLDELAGDEFGGASVIRGVAG
AAGKTVFVFPGQGSQWIGMGIELLDTAPVFARHIESCGQAFAEFVDWSLLDVLRGAAGAPGLDRVDVVQP
VLFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDAAKVVTLRSKLLVGLAGPGGMVSVAC
GEQQARELLEPFGDRVSIAAINGPSAVVVSGEVAALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQ
LTEVLAGIEPLSSRTAFFSSVTGSRLDTAELDAEYWYRNIRQTVQFDQAVRSACGHGYRTFIESSPHPAL
IAGIEDTYRNCAADSGADPIVVPTLGREDGGLQRFLASAAAAFVAGVNVDWRGPLDGAGLVELPTYAFEK
RRFWLSGEGVSVDASGLGLSAGGHALLGAVVELPESGGVVLTGRLALGAHGWLADHAVSGVVVFPGTGFV
ELAIRAGDEVGCSVVNELTLRTPLVLPASGSVAVQVVVGAAADSAERSVSIYSRTDTDAGSVWVCHAEGT
LGADSAQPAADLSAWPPAGAIAVDVADGYERLDARGYGYGPAFRGLTAMWARGEELFAEVRLPEAAGSTS
GFGVHPALLDAALHTAVIANPDAELVLPFSWQGVSLHAAGAASVRVRIAPVGPSSVSVELADDLGLPVLS
VKAMVARPVSEQQMRAVVSASGPDRLFEVVWTPMTVAATDAAPAYELFESVAAEGDPLSGTYQRTHQALA
AVQSWLTEHDSGVLVVATRGAMALAGEDVTDLAGAAVWGLVRSAQTENPGRLVLVDSDAAVDAAAVATAL
AVGEPQVVLRNGQPYTARVHASRAADGILVPPVDGPWRLGLSSAGTFENLQLEPVPNAGAPLGPGQVRVA
MRAIAANFRDIMITLGMFTHDALIGGEGAGVVVEIGPEVTEFAVGDAVYGFFPDGSGTLVAGDVRLLLPK
PADWSYAEAAAISAVFTTAYYAFVHLANVQPGQRVLVHAATGGVGMAAVQLARHLGLEVYATASKGKWDI
LRAMGFDEDHISDSRSLEFEEKFREVTGGRGVDVVLDSLAGEFVDASLRLLGPGGVFLEMGKTDIRDPGV
IAQEYPGVRYRAFDLFEPGRPRMHQYMLDLAGLFDAGVLRPLPVTAFDVRRAPAALRYLSQARHIGKVVM
TMPADQGGALGGGTVLITGGTGMAGSALARHLVAHHGVAHLVLISRRGPAAPGATELVAELSAAGAQVEV
VACDAADRPALAKVIAEIPAQRPLSAVVHAGGVLDDAVISSLTPERVDTVLRAKVDAAWNLHELTRDLDL
SAFVMFSSMAGVVGSSGQANYAAANTFVDGLAAHRRAHGLPAISLGWGLWDQASDMTGGMDAADRARLGR
EGVLALSSDEAMELFDTALIVNQAFLAPARIDLAALRAHAVAVPPMFSDLVSAPTRRQVDDALAAAKSKS
ALAHRLHGLPEPEQHAVVLDLVRSHIATVLGTITPEAIDPDKAFQELGFDSLTAVEMRNRIKTVTGLSLS
PTLIFDYPTPNGLANYIRAELAGAPQEVKHTPAVRVTGDDPIAIVGMSCRYPGGIESPDDLWDMLMARRD
VLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFDPAFFGVGPSEALAMDPQQRMFLELSWEA
LERAGIEPGGLRGSATGVFAGVMTQGYGMFAAEPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACS
SSLVALHMAVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLSADGRCKAFAGAADGTGFSEGGGMLV
VERLSDAQRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTL
GDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVLPATLHVDVPS
PHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVV
SAKSGSALGAQAARLAAHVRSHDELDVADVGWSLAGRSTFEHRAVVLGVDRDGLLAGLDELAGDEFGGAS
VIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVIWGHDENLLNT
TEFAQPALFAVEVALYRLLESWGVRPDFVMGHSVGELSAAHVAGVLSLENAAVLVAARGRLMQALPDGGA
MIAVQATEQEVLPLLGAQVSIAAINGPASVVISGAQDAVSAVAEQLRADGRRVHRLAVSHAFHSPLMDPM
IDEFATVAGELTVNAPTIGIISNLTGQLAGEDFGSAAYWKRHVRDAVRFADSIRFAQSAGAARFLEVGPS
SGLTASIEEVLSDAAVTNPVATASALRKDRPEPVSLVSAVAGVFVAGTAVDWRAVVGQSNFVELPTYAFE
RRRFWLSGDAVAADAAGLGLQAGEHALLGAVVELPASGGVVLTGRLSLAAQGWLADHAVGGVVIFPGAGF
VELAIRAGDEVGCRVVDELTLAAPLVLPSGGSVAVQVVVGSPDDSGARAVSVYSRGDAGSDWVLHAEGSL
GSGSPEPATDLSTWPPVGAVEVENADGYQQLAERGYGYGPAFRGLNAMWRRGDEVFAEVALPADAGVSVS
GFGIHPVMLDAALHAVILASDGADDFGVPEGSVLVPFAWQGVTLHAAGASAVRARIAPAGPSAVSIELSD
GLGLPVLSVASMLARPVTDQQLRAAVSGAGPDRLFGVDWTAQPSAELQPVPVRIWGAVESEGDDDPGASV
VFESVPQAGEVVAGVYAATAAVLEVLRSWLSRDGAGQLVITTRGAVALPDEDVTDLAGSAVWGLVRSAQT
EHPGRIVLVDTDAQLDEHAVAAVLAAGEPQVLWRNGEVYTARVHGSRAVAGLLVPPGDGPWRLGMSTAGT
FENLRLEPIPDADAALQPGHVRVALSAMAANFRDVMIALGLYPDPDAAMGVEGAGVVVETASTDGRFAVG
DRVVGLFPEGTGTIAITDHRLLVKIPAGWSDTAAATTSVVFATAFYALRDLASVQPGQRILVHAATGGVG
MAAVQLARHWGLEVFATASKGKWDTLRAMGFDEDHIGDSRSLEFEDKFRAATGGRGMDVVLDSLAGEFVD
ASLRLVAPGGVFLEMGKTDIREAAVVAQQHTGVRYRAFDLFEAGPDHIAQILAELAALFSEDALRPLPVT
TFDVRRAPAALRYLSQARHVGKVVLTMPDAWAAGTVLITGGTGMAGSALARHVVAHHGVRQLVLVSRRGP
DAPGAAELAEELSAFGAQVQVVACDAADRAALAKLIADIPVQHPLSAVIHTAGALDDAVVTSLTPERMET
VLRAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQGNYAAANSFLDGLAVHRQAHGLPAISLGWGL
WDQASNMTGGLAAVDFKRFARDGIVAMSSDEALGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMF
VDLINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIATVLGNSSPDAIDPDRAFQEL
GFDSLTAVEMRNRLKSATGLALSPTLIFDYPNSAALAGYMHRELVGASPQSDITAEAPGEAELQRVVASI
PVKRLRQAGVLELLLALANETGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_3025pks12-100% (4187)polyketide synthase, Pks12
M. marinum MMMAR_3798-0.045.23% (3111) type I modular polyketide synthase
M. marinum MMMAR_2471pks70.060.28% (2062) polyketide synthase Pks7

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2074cpks120.082.98% (4188) polyketide synthase pks12
M. gilvum PYR-GCKMflv_0405-0.036.64% (2549) beta-ketoacyl synthase
M. tuberculosis H37RvRv2048cpks120.083.19% (4188) polyketide synthase pks12
M. leprae Br4923MLBr_00135-0.058.20% (2079) putative polyketide synthase
M. abscessus ATCC 19977MAB_3148c-0.034.08% (2142) polyketide synthase Pks5
M. avium 104MAV_2450-0.080.27% (4206) erythronolide synthase, modules 3 and 4
M. smegmatis MC2 155MSMEG_0408-0.036.41% (2538) type I modular polyketide synthase
M. thermoresistible (build 8)TH_4621-0.035.54% (1854) PUTATIVE mycocerosic acid synthase
M. ulcerans Agy99MUL_2266pks120.099.21% (4191) polyketide synthase, Pks12
M. vanbaalenii PYR-1Mvan_1003-0.037.18% (2528) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0405|M.gilvum_PYR-GCK          -----------------------MGSAAHQGE-SAHRFAIVGYAGRFPG-
MSMEG_0408|M.smegmatis_MC2_155      -----------------------MVSAEHPIE-PTPSFAIIGYAARFPG-
Mvan_1003|M.vanbaalenii_PYR-1       ---------MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPG-
MMAR_3025|M.marinum_M               -MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG
MUL_2266|M.ulcerans_Agy99           -MVDQLQHATEALRKALVQVERLKRTKRALLERSSEPIAIVGMSCRFPGG
Mb2074c|M.bovis_AF2122/97           -MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG
Rv2048c|M.tuberculosis_H37Rv        -MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG
MAV_2450|M.avium_104                MMVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ARDAESFWELLADGRDAISEVPEDR-WDVEAFFDPDPSTPGKVVTRRAGF
MSMEG_0408|M.smegmatis_MC2_155      AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAGF
Mvan_1003|M.vanbaalenii_PYR-1       AADADEFWDVLRGGRDAISEVPQDR-WDADEFFDADPEAAGKMVTRRAGF
MMAR_3025|M.marinum_M               VDSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHKSYASTGGF
MUL_2266|M.ulcerans_Agy99           VDSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHKSYASTGGF
Mb2074c|M.bovis_AF2122/97           VDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGF
Rv2048c|M.tuberculosis_H37Rv        VDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGF
MAV_2450|M.avium_104                VDSPEALWQMVAEGRDVISEFPTDRGWDLAALYDPDPDARHKCYVNTGGF
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VDDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANT
MSMEG_0408|M.smegmatis_MC2_155      VDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANS
Mvan_1003|M.vanbaalenii_PYR-1       VEDVAGFDAPFFGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGT
MMAR_3025|M.marinum_M               VDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGS
MUL_2266|M.ulcerans_Agy99           VDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGS
Mb2074c|M.bovis_AF2122/97           VDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGS
Rv2048c|M.tuberculosis_H37Rv        VDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGS
MAV_2450|M.avium_104                VDNVADFDPAFFGIAPSEALAMDPQHRMLLELSWEALERAGIDPSGLRGS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          NTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQ
MSMEG_0408|M.smegmatis_MC2_155      NTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQ
Mvan_1003|M.vanbaalenii_PYR-1       RTGVFMGLSTHDYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQ
MMAR_3025|M.marinum_M               ATGVFAGLIVQGYG------MFAEEIEGYRLTGMTSSVASGRVAYVLGLE
MUL_2266|M.ulcerans_Agy99           ATGVFAGLIVQGYG------MFAEEIEGYRLTGMTSSVASGRVAYVLGLE
Mb2074c|M.bovis_AF2122/97           ATGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLE
Rv2048c|M.tuberculosis_H37Rv        ATGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLE
MAV_2450|M.avium_104                ATGVFAGLIVQGYG------MLAEEIEGYRLTGMTSSVASGRVSYVLGLE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GPAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVILTPATMITFS
MSMEG_0408|M.smegmatis_MC2_155      GPAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFS
Mvan_1003|M.vanbaalenii_PYR-1       GPAVAVDTACSSSLVAVHQACQALRLAECDVALAGGVNVLLSPATMINFS
MMAR_3025|M.marinum_M               GPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFS
MUL_2266|M.ulcerans_Agy99           GPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFS
Mb2074c|M.bovis_AF2122/97           GPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFS
Rv2048c|M.tuberculosis_H37Rv        GPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFS
MAV_2450|M.avium_104                GPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          NAHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIR
MSMEG_0408|M.smegmatis_MC2_155      NAHMLAPDGRCKTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIR
Mvan_1003|M.vanbaalenii_PYR-1       RARMLAPDGRCKTFDATADGYVRGEGCGVVVVKRLADAIRHGDRIRAVIR
MMAR_3025|M.marinum_M               RHRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDAQRLGHPVLALVR
MUL_2266|M.ulcerans_Agy99           RHRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDAQRLGHPVLALVR
Mb2074c|M.bovis_AF2122/97           RHRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVV
Rv2048c|M.tuberculosis_H37Rv        RHRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVV
MAV_2450|M.avium_104                RHRGLAPDGRCKAYAGAADGVGWSEGGAMLVVERLSDARRLGHPVLAVVR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GSAINQDGASGGLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTS
MSMEG_0408|M.smegmatis_MC2_155      GSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVGYLEAHGTGTS
Mvan_1003|M.vanbaalenii_PYR-1       GSAVNQDGASGGLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTP
MMAR_3025|M.marinum_M               GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
MUL_2266|M.ulcerans_Agy99           GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
Mb2074c|M.bovis_AF2122/97           GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
Rv2048c|M.tuberculosis_H37Rv        GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
MAV_2450|M.avium_104                GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LGDPIEAQAAGAALGPGREPQ----RPLLIGSAKTNIGHLEAAAGIAGVI
MSMEG_0408|M.smegmatis_MC2_155      LGDPIEAQAAGEVLGAGRAPE----EPLLIGSAKTNIGHLEAAAGIAGVI
Mvan_1003|M.vanbaalenii_PYR-1       LGDPIEVQAAGAVLGVGREPD----RPLLIGSVKTNIGHLEAASGIAGLL
MMAR_3025|M.marinum_M               LGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVI
MUL_2266|M.ulcerans_Agy99           LGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVI
Mb2074c|M.bovis_AF2122/97           LGDPIEAQALLATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVI
Rv2048c|M.tuberculosis_H37Rv        LGDPIEAQALLATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVI
MAV_2450|M.avium_104                LGDPIEAQALLATYGQDRGQP------LWLGSIKSNMGHTQAAAGVAGVI
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          KVVLSLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPR
MSMEG_0408|M.smegmatis_MC2_155      KVVMALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR---NGKPR
Mvan_1003|M.vanbaalenii_PYR-1       KVILSLEHQVLPKHLNFRSPSPHIPWNRLPVRIVDDPVPWTR---SGRSR
MMAR_3025|M.marinum_M               KMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVR
MUL_2266|M.ulcerans_Agy99           KMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVR
Mb2074c|M.bovis_AF2122/97           KMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTR
Rv2048c|M.tuberculosis_H37Rv        KMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTR
MAV_2450|M.avium_104                KMVLAMRHELLPATLHVDEPSPHVDWSAGAVSLLTEAQPWP----GERPR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          IAGVSSFGFAGTNAHVILEEAPLAAEPAQES--VDDGRFTLLPLSARTPA
MSMEG_0408|M.smegmatis_MC2_155      IAGVSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPE
Mvan_1003|M.vanbaalenii_PYR-1       VAGISSFGFSGTNAHVLVEEAPRADRAGAAPQPAAPGGFGMLPLSARTPD
MMAR_3025|M.marinum_M               RAGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVVS---AKSGS
MUL_2266|M.ulcerans_Agy99           RAGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVPWVVS---AKSGS
Mb2074c|M.bovis_AF2122/97           RAGVSSFGISGTNAHVIIEAVPVVPRR-EAGWAGPVVPWVVS---AKSES
Rv2048c|M.tuberculosis_H37Rv        RAGVSSFGISGTNAHVIIEAVPVVPRR-EAGWAGPVVPWVVS---AKSES
MAV_2450|M.avium_104                RAGVSSFGISGTNAHVIIEAVPAVEPAHADAPALPVLPWVVS---AKSAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ALMAVADRYRDWLVANPDATLADLCFTAGTARSHLEHRAALVVNTREAAL
MSMEG_0408|M.smegmatis_MC2_155      ALVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAI
Mvan_1003|M.vanbaalenii_PYR-1       ALAATAHRLRTWLAANPDASWPDLCFTAAVGRSHLRHRAALVVDSRSSVE
MMAR_3025|M.marinum_M               ALGAQAARLAAHVRSHDELDVADVGWSLAG-RSTFEHRAVVLGVDRDGLL
MUL_2266|M.ulcerans_Agy99           ALGAQAARLAAHVRSHDELDVADVGWSLAG-RSTFEHRAVVLGADRDGLL
Mb2074c|M.bovis_AF2122/97           ALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLL
Rv2048c|M.tuberculosis_H37Rv        ALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLL
MAV_2450|M.avium_104                ALRAQAARLAEYVRAQGELDIADVGWTLAG-RATFEHRAVVVGGDRDRLL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DLLGALADDRPA-PGLVRGESHDTPKTAWLFTGQGSQYPGMSRELFDTEP
MSMEG_0408|M.smegmatis_MC2_155      ELLGALADDRPA-PGLVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEP
Mvan_1003|M.vanbaalenii_PYR-1       ELLGALAEDRPG-PGLARGECGDPPKTAWLFTGQGSQYPGMGRELFDTEP
MMAR_3025|M.marinum_M               AGLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQWIGMGIELLDTAP
MUL_2266|M.ulcerans_Agy99           AGLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQWIGMGIELLDTAP
Mb2074c|M.bovis_AF2122/97           AGLDELAGDQLG-GSVVRGTATAAGKTVFVFPGQGSQWLGMGIELLDTAP
Rv2048c|M.tuberculosis_H37Rv        AGLDELAGDQLG-GSVVRGTATAAGKTVFVFPGQGSQWLGMGIELLDTAP
MAV_2450|M.avium_104                AGLDELAADDPA-ASIIRGVATPAGKTVFVFPGQGSQWLGMATELLDTAP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LFAETLRECAAAVDGMLEKPLLDVIFDTDGVLDTDSNETLRHTSYAQPAL
MSMEG_0408|M.smegmatis_MC2_155      VFAETVRKCAEAVADILEKPLLDVIFDAD-ELDGDTESPLRHTTYAQPAL
Mvan_1003|M.vanbaalenii_PYR-1       VYREVMTRCAEAVADVLERPLLDVVFDAD------GGEALRHTSYAQPAL
MMAR_3025|M.marinum_M               VFARHIESCGQAFAEFVDWSLLDVLRGAA------GAPGLDRVDVVQPVL
MUL_2266|M.ulcerans_Agy99           VFARHIESCGQAFAEFVDWSLLDVLRGAA------GAPGLDRIDVVQPVL
Mb2074c|M.bovis_AF2122/97           AFAQQIDACAEAFAEFVDWSLVDVLRGAP------GAPGLDRVDVVQPVL
Rv2048c|M.tuberculosis_H37Rv        AFAQQIDACAEAFAEFVDWSLVDVLRGAP------GAPGLDRVDVVQPVL
MAV_2450|M.avium_104                VFAQHIQACEEAFAEFVDWSLIDALRGAP------GAAGMDRVDVVQPAL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          FAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLSLRDGARLMAER
MSMEG_0408|M.smegmatis_MC2_155      FAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAER
Mvan_1003|M.vanbaalenii_PYR-1       YAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAER
MMAR_3025|M.marinum_M               FAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDAAKVVTLR
MUL_2266|M.ulcerans_Agy99           FAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDAAKVVTLR
Mb2074c|M.bovis_AF2122/97           FAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLR
Rv2048c|M.tuberculosis_H37Rv        FAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLR
MAV_2450|M.avium_104                FAVMVSLAELWKSVGVSPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GRLFGSLPSGGRMAAVFAAAERVEALTDEY-PALSVAAYNG-ANTVLSGP
MSMEG_0408|M.smegmatis_MC2_155      GRLFGSLPAGGRMAAVFTAPERAERLTDEY-PSLSVAAYNG-ANTVLSGP
Mvan_1003|M.vanbaalenii_PYR-1       GRLFGSLPEGGRMAAVFAPADRVESCTVDS-PLLSVAAYNG-DNTVLSGP
MMAR_3025|M.marinum_M               SKLLVGLAGPGGMVSVACGEQQARELLEPFGDRVSIAAINGPSAVVVSGE
MUL_2266|M.ulcerans_Agy99           SKLLVGLAGPGGMVSVACGEQQARELLEPFGDRVSIAAINGPSAVVVSGE
Mb2074c|M.bovis_AF2122/97           SKLLAGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGE
Rv2048c|M.tuberculosis_H37Rv        SKLLAGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSGE
MAV_2450|M.avium_104                SKLLRSLAGPGGMLSIACSTERARELLAPYGNRVSIAAVNGRSAVVVSGE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ATDLERAVAGLVADGVRCDWLETSHAFHSALLDPILDDFESYARGITFTA
MSMEG_0408|M.smegmatis_MC2_155      AKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYRE
Mvan_1003|M.vanbaalenii_PYR-1       AGDLERAVAGFSAAGVRCDWLDTSHAFHSALLDPVLEEFESCADRFEFGT
MMAR_3025|M.marinum_M               VAALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQLTEVLAGIEPLS
MUL_2266|M.ulcerans_Agy99           VAALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQLTEVLAGIEPLS
Mb2074c|M.bovis_AF2122/97           VGALEELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAEALSGIEPRS
Rv2048c|M.tuberculosis_H37Rv        VGALEELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAEALSGIEPRS
MAV_2450|M.avium_104                GAALDELAAFCADLALRTRRIDVDYASHSVEVEAIREDLAQALTGIEPRS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PQRILIDNRTGAALGRSVTLDAAYWRRHARQPVEFAKSVHTLADMNCKLL
MSMEG_0408|M.smegmatis_MC2_155      PQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRVL
Mvan_1003|M.vanbaalenii_PYR-1       PQRTLVCNRSGEVLSRHARLDGQYWRRHARQPVRFAESVRTLADLGCRLL
MMAR_3025|M.marinum_M               SRTAFFSSVTGSRLD-TAELDAEYWYRNIRQTVQFDQAVRSACGHGYRTF
MUL_2266|M.ulcerans_Agy99           SRTAFFSSVTGSRLD-TAELDAEYWYRNIRQTVQFDQAVRSACGHGYRTF
Mb2074c|M.bovis_AF2122/97           TRTVFFSTVTGNRLD-TAGLDADYWYRNVRQTVLFDQAVRNACEQGYRTF
Rv2048c|M.tuberculosis_H37Rv        TRTVFFSTVTGNRLD-TAGLDADYWYRNVRQTVLFDQAVRNACEQGYRTF
MAV_2450|M.avium_104                SRIAFFSTVTGNRLD-TAGLDADYWYRNIRQTVQFDQTVRSAAEHGYRTF
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VEIGPRPVLTAAALSAWP----DPATSPRVIASLRRTTADQRQITEAVAD
MSMEG_0408|M.smegmatis_MC2_155      LEIGPRPVLTATALAAWP----DPATTPQVLASLRPTTADHRQITEAVAA
Mvan_1003|M.vanbaalenii_PYR-1       MEIGPQPVLTAAAMRTWP----GTVTAPRVAASMRRKGSDRRQITEALAQ
MMAR_3025|M.marinum_M               IESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGREDGGLQRFLASAAA
MUL_2266|M.ulcerans_Agy99           IESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGREDGGLQRFLASAAA
Mb2074c|M.bovis_AF2122/97           IESSPHPALITGVEETFAACTDGD-SEAIVVPTLGRGDGGLHRFLLSAAS
Rv2048c|M.tuberculosis_H37Rv        IESSPHPALITGVEETFAACTDGD-SEAIVVPTLGRGDGGLHRFLLSAAS
MAV_2450|M.avium_104                IESSPHPALVAGIEDTVNDSLPGD-TEAIVIPTLGRDDGGLERFLTSAAT
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDSR------EPVAA
MSMEG_0408|M.smegmatis_MC2_155      AYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTASA
Mvan_1003|M.vanbaalenii_PYR-1       AYVAGHRPETAARQHGRGRLLDLPTYPFQHRAYWFPQGQ--------ART
MMAR_3025|M.marinum_M               AFVAGVNVDWRGPLDG-AGLVELPTYAFEKRRFWLSGEGVSVDASGLGLS
MUL_2266|M.ulcerans_Agy99           AFVAGVNVDWRGPLDG-AGLVELPTYAFEKRRFWLSGEGVSVDASGLGLS
Mb2074c|M.bovis_AF2122/97           AFVAGVAVNWRGTLDG-AGYVELPTYAFDKRRFWLSAEGSGADVSGLGLG
Rv2048c|M.tuberculosis_H37Rv        AFVAGVAVNWRGTLDG-AGYVELPTYAFDKRRFWLSAEGSGADVSGLGLG
MAV_2450|M.avium_104                AFVAGVNVAWRGVLDG-AGFVELPTYAFDRRRFWLSGEGAAADASGLGLG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          APQRGARTETVRLLEDGRIEELAALLGG----------------------
MSMEG_0408|M.smegmatis_MC2_155      GSVTPHRTQAVRLLEDGQIEELAALIDG----------------------
Mvan_1003|M.vanbaalenii_PYR-1       APTDPVHTETVRFLDEERIDELAALLDG----------------------
MMAR_3025|M.marinum_M               AGGHALLGAVVELPESGGVVLTGRLALGAHGWLADHAVSGVVVFPGTGFV
MUL_2266|M.ulcerans_Agy99           AGGHALLGAVVELPESGGVVLTGRLALGAHGWLADHAVSGVVVFPGTGFV
Mb2074c|M.bovis_AF2122/97           ASEHPLLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDVVLFPGTGFV
Rv2048c|M.tuberculosis_H37Rv        ASEHPLLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDVVLFPGTGFV
MAV_2450|M.avium_104                TSEHPLLSAVVELPASGGVVLTGRLSPSLQGWLTDHAVSGTVVFPGAGFV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ----TVDDPFTFDVLNRLAAQHNQQRSTE---------------------
MSMEG_0408|M.smegmatis_MC2_155      ----ETVDEQTLRVLNKLAARHNQQRSTH---------------------
Mvan_1003|M.vanbaalenii_PYR-1       ----PTGSAQTVDVLSKLAARHRQQRGAQ---------------------
MMAR_3025|M.marinum_M               ELAIRAGDEVGCSVVNELTLRTPLVLPAS----GSVAVQVVVGAAADSAE
MUL_2266|M.ulcerans_Agy99           ELAIRAVDEVGCSVVNELTLRTPLVLPAS----GSVAVQVVVGAAADSAE
Mb2074c|M.bovis_AF2122/97           ELAIRAGDEVGCSVLDELTLAAPLLLPAT----GSVAVQVVVDAGRDSNS
Rv2048c|M.tuberculosis_H37Rv        ELAIRAGDEVGCSVLDELTLAAPLLLPAT----GSVAVQVVVDAGRDSNS
MAV_2450|M.avium_104                ELAIRAGDEVGCSTVEELTLQAPLMLPAKDSGIGSVAVQVLVGEADESGR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------SIADDRYQIRWETAAEPPVGADAADGITWLLVGDDT
MSMEG_0408|M.smegmatis_MC2_155      --------------VDPDARYEIRWDAIASAAASTGAAA--DWILVGDDT
Mvan_1003|M.vanbaalenii_PYR-1       --------------SIADARYQIRWEKSEAPGAARPTTEATTWLLVTHDS
MMAR_3025|M.marinum_M               RSVSIYSR----TDTDAGSVWVCHAEGTLGADSAQPAADLSAWPPAGAIA
MUL_2266|M.ulcerans_Agy99           RSVSIYSRTDTDTDTDAGSVWVCHAEGTLGADSAQPAADLSAWPPAGAIA
Mb2074c|M.bovis_AF2122/97           RGVSIFSR------ADAQAGWLLHAEGILRPGSVEPGADLSVWPPAGAVT
Rv2048c|M.tuberculosis_H37Rv        RGVSIFSR------ADAQAGWLLHAEGILRPGSVEPGADLSVWPPAGAVT
MAV_2450|M.avium_104                RDVSIFSR------PDSDSPWVCHAQGTLSTGSIEPGADLAAWPPAGATK
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DATRPLVDVLAARGHRY--RILGLPKSGAEEHELADTLRDAAADATDL--
MSMEG_0408|M.smegmatis_MC2_155      AAVLEFADALTAGGHRH--QIVALPGSDADEAQLVDTLR--AASAGEL--
Mvan_1003|M.vanbaalenii_PYR-1       RAAQPIAEVLERRGHPY--HIVGLPGSDADAAPAEEALR-ATVSQPRP--
MMAR_3025|M.marinum_M               VDVADGYERLDARGYGYGPAFRGLTAMWARGEELFAEVRLPEAAGSTSGF
MUL_2266|M.ulcerans_Agy99           VDVADGYERLDARGYGYGPAFRGLTAMWARGEELFAEARLPEAAGSTSGF
Mb2074c|M.bovis_AF2122/97           VDVADGYERLATRGYRYGPAFRGLTAMWARGEEIFAEVRLPEAAGGVGGF
Rv2048c|M.tuberculosis_H37Rv        VDVADGYERLATRGYRYGPAFRGLTAMWARGEEIFAEVRLPEAAGGVGGF
MAV_2450|M.avium_104                VDIADGYQRLAARGYGYGPAFQGLTAAWVRGDEVFAEVRLPDAAGGVTGF
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3025|M.marinum_M               GVHPALLDAALHTAVI----ANPDAELVLPFSWQGVSLHAAGAASVRVRI
MUL_2266|M.ulcerans_Agy99           GVHPALLDAALHTAVI----ANPDADLVLPFSWQGVSLHAAGAASVRVRI
Mb2074c|M.bovis_AF2122/97           GVHPALLDAVLHAVVI----AGDPDELALPFAWQGVSLHATGASAVRARI
Rv2048c|M.tuberculosis_H37Rv        GVHPALLDAVLHAVVI----AGDPDELALPFAWQGVSLHATGASAVRARI
MAV_2450|M.avium_104                GVHPALLDAAMHALIVGHQIAGDTDEVALPFAWQGVSLHAAGASAVRARL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3025|M.marinum_M               APVGPS------SVSVELADDLGLPVLSVKAMVARPVSEQQMRAVVSASG
MUL_2266|M.ulcerans_Agy99           APVGPS------SVSVELADDLGLPVLSVKAMVARPVSEQQMRAVVSASG
Mb2074c|M.bovis_AF2122/97           APAGPS------AVSVELADGLGLPVLSVASMVARPVTERQLLAAVSGSG
Rv2048c|M.tuberculosis_H37Rv        APAGPS------AVSVELADGLGLPVLSVASMVARPVTERQLLAAVSGSG
MAV_2450|M.avium_104                APAQAPGTAASRAVSLELADGLGLPVLSVRAMVARSVSERQLRAAVSAAG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ----------RIVHVAALDAAESDTSMKSLLRMQHRVLGGTRRLFGAAVA
MSMEG_0408|M.smegmatis_MC2_155      ----------YVVHIAAGDGAAAP--MRDLLRVQHRTLGGLRRLFRAAND
Mvan_1003|M.vanbaalenii_PYR-1       ----------HILYLAALEEPGGS-AAETLGWMQHRVLAAARRLFQLAAT
MMAR_3025|M.marinum_M               PDRLFEVVWTPMTVAAT-DAAPAYELFESVAAEGDPLSGTYQRTHQALAA
MUL_2266|M.ulcerans_Agy99           PDRLFEVVWTPMTVAAT-DAAPAYELFESIAADGDPLSGTYQRTHQALAA
Mb2074c|M.bovis_AF2122/97           PDRLFEVIWSPASAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQALAA
Rv2048c|M.tuberculosis_H37Rv        PDRLFEVIWSPASAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQALAA
MAV_2450|M.avium_104                PDRLFEVAWAPVTVPAAHGEPPVHQVFESLAAEGDPVGESYRRTHEALAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AQ------LRSPMWLVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHP--
MSMEG_0408|M.smegmatis_MC2_155      AE------LRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELP--
Mvan_1003|M.vanbaalenii_PYR-1       AG------ARAPIWLITAGAQRITGDETVEPAQTSLWGFGRAAALEQP--
MMAR_3025|M.marinum_M               VQSWLTEHDSGVLVVATRGAMALAGEDVTDLAGAAVWGLVRSAQTENPGR
MUL_2266|M.ulcerans_Agy99           VQSWLTEHDSGVLVVATRGAMALAGEDVTDLAGAAVWGLVRSAQTENPGR
Mb2074c|M.bovis_AF2122/97           VQSWLTDHESGVLVVATRGAMALPREDVADLAGAAVWGLVRSAQTEHPGR
Rv2048c|M.tuberculosis_H37Rv        VQSWLTDHESGVLVVATRGAMALPREDVADLAGAAVWGLVRSAQTEHPGR
MAV_2450|M.avium_104                VQSWLTEHDSGVLVVVTRGAMALAGEDVTDLSGAAVWGLVRSAQTEHPGR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3025|M.marinum_M               LVLVDSDAAVDAAAVATALAVGEPQVVLRNGQPYTARVHASRAADGILVP
MUL_2266|M.ulcerans_Agy99           LVLVDSDAAVDAAAVATALAVGEPQVVLRNGQPYTARVHASRAADGILVP
Mb2074c|M.bovis_AF2122/97           IVLVDSDAATDDAAIAMALATGEPQVVLRGGQVYTARVRGSRAADAILVP
Rv2048c|M.tuberculosis_H37Rv        IVLVDSDAATDDAAIAMALATGEPQVVLRGGQVYTARVRGSRAADAILVP
MAV_2450|M.avium_104                IVLIDSDAALDDSALTAALATGEPQVLLRDGTVYTARVHGSRAVDGIMTP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3025|M.marinum_M               PVDGPWRLGLSSAGTFENLQLEPVPNAGAPLGPGQVRVAMRAIAANFRDI
MUL_2266|M.ulcerans_Agy99           PVDGPWRLGLSSAGTFENLQLEPVPNAGAPLGPGQVRVAMRAIAANFRDI
Mb2074c|M.bovis_AF2122/97           PGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMRAIAANFRDI
Rv2048c|M.tuberculosis_H37Rv        PGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMRAIAANFRDI
MAV_2450|M.avium_104                PEDRPWRLGISSAGTFENLQLEPVPNPDAALQPGQVRVALRAIATNFRDV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3025|M.marinum_M               MITLGMFTHDALIGGEGAGVVVEIGPEVTEFAVGDAVYGFFPDGSGTLVA
MUL_2266|M.ulcerans_Agy99           MITLGMFTHDALIGGEGAGVVVEIGPEVTEFAVGDAVYGFFPDGSGTLVA
Mb2074c|M.bovis_AF2122/97           MITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFFPDGSGTLVA
Rv2048c|M.tuberculosis_H37Rv        MITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFFPDGSGTLVA
MAV_2450|M.avium_104                MITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVYGFFPDGSGTLVP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3025|M.marinum_M               GDVRLLLPKPADWSYAEAAAISAVFTTAYYAFVHLANVQPGQRVLVHAAT
MUL_2266|M.ulcerans_Agy99           GDVRLLLPKPADWSYAEAAAISAVFTTAYYAFVHLANVQPGQRVLVHAAT
Mb2074c|M.bovis_AF2122/97           GDVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQPGQRVLIHAGT
Rv2048c|M.tuberculosis_H37Rv        GDVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQPGQRVLIHAGT
MAV_2450|M.avium_104                GDVRLLQHKPTHWSYPEAAGISAVFTTAYMAFIHLADVKPGQRVLVHAAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ----------QIWGGLADLGGGTSDEWSRLLNR------IAATHDPAVME
MSMEG_0408|M.smegmatis_MC2_155      ----------HIWGGLADLSG-ADTEWPRLIAR------ITSPRD---GE
Mvan_1003|M.vanbaalenii_PYR-1       ----------ELWGGLADVTTGDAEEWSALIDH------IVAAPT---SE
MMAR_3025|M.marinum_M               GGVGMAAVQLARHLGLEVYATASKGKWDILRAMGFDEDHISDSRSLEFEE
MUL_2266|M.ulcerans_Agy99           GGVGMAAVQLARHLGLEVYATASKGKWDILRAMGFDEDHISDSRSLEFEE
Mb2074c|M.bovis_AF2122/97           GGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEFED
Rv2048c|M.tuberculosis_H37Rv        GGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEFED
MAV_2450|M.avium_104                GGVGMAAVQLARHLGLEVFATASRGKWDTLRAMGFDDDHIGDSRTLEFED
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DQVAVRGSTSYVPRLVHRDTLPSGKPLHLRA-------------------
MSMEG_0408|M.smegmatis_MC2_155      DQIALRGDAVYAPRLVRRTGEPSDTPLPVRE-------------------
Mvan_1003|M.vanbaalenii_PYR-1       DQIAVRGREIHVARLTRCAEKANAAALELRR-------------------
MMAR_3025|M.marinum_M               KFREVTGGRGVDVVLDSLAGEFVDASLRLLGPGGVFLEMGKTDIRDPGVI
MUL_2266|M.ulcerans_Agy99           KFREVTGGRSVDVVLDSLAGEFVDASLRLLGPGGVFLEMGKTDIRDPGVI
Mb2074c|M.bovis_AF2122/97           KFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGVI
Rv2048c|M.tuberculosis_H37Rv        KFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGVI
MAV_2450|M.avium_104                KFRSATGGAGMDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGVV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3025|M.marinum_M               AQEYPGVRYRAFDLFEPGRPRMHQYMLDLAGLFDAGVLRPLPVTAFDVRR
MUL_2266|M.ulcerans_Agy99           AQEYPGVRYRAFDLFEPGRPRMHQYMLDLAGLFDAGVLRPLPVTAFDVRR
Mb2074c|M.bovis_AF2122/97           AQQYPGVRYRAFDLFEAGPDRIAQILAELATLFGDGVLRPLPVTTFDVRR
Rv2048c|M.tuberculosis_H37Rv        AQQYPGVRYRAFDLFEPGRPRMHQYMLELATLFGDGVLRPLPVTTFDVRR
MAV_2450|M.avium_104                AREYPGVRYRAFDLFEPGRPRMRQWMVELAGLFDAGVLNPLPVTTFDIRR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ------------------------------DATYLVTGGLGSLGLEIAGY
MSMEG_0408|M.smegmatis_MC2_155      ------------------------------DRTYLVTGGLGAIGLEVAGY
Mvan_1003|M.vanbaalenii_PYR-1       ------------------------------EATYLVTGGLGALGLEVAEF
MMAR_3025|M.marinum_M               APAALRYLSQARHIGKVVMTMPADQGGALGGGTVLITGGTGMAGSALARH
MUL_2266|M.ulcerans_Agy99           APAALRYLSQARHVGKVVMTMPADQGGALGGGTVLITGGTGMAGSALARH
Mb2074c|M.bovis_AF2122/97           APAALRYLSQARHTGKVVMLMPG----SWAAGTVLITGGTGMAGSAVARH
Rv2048c|M.tuberculosis_H37Rv        APAALRYLSQARHTGKVVMLMPG----SWAAGTVLITGGTGMAGSAVARH
MAV_2450|M.avium_104                GRAALRYLSQARHIGKVVMTVPG----ALSAGTVLITGGTGMAGSTLARH
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LAA-NGAGHLVLTSRRTPDEAAASRIEALRERHGCEVRVVTADVADAHAV
MSMEG_0408|M.smegmatis_MC2_155      LAS-HGAGHVVLTSRREPGDDARRRLDGLREQYACDVRVITADVADAHDV
Mvan_1003|M.vanbaalenii_PYR-1       LAS-HGAGHLVLTGRRSASDTVRQRIDAMRERFDCQVLVATADVADRDDV
MMAR_3025|M.marinum_M               LVAHHGVAHLVLISRRGPAAPGATELVAELSAAGAQVEVVACDAADRPAL
MUL_2266|M.ulcerans_Agy99           LVAHHGVAHLVLISRRGPAAPGATELVAELSAAGAQVEVVACDAADRPAL
Mb2074c|M.bovis_AF2122/97           VVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRAAL
Rv2048c|M.tuberculosis_H37Rv        VVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRAAL
MAV_2450|M.avium_104                LVTGHGVRDLALLSRTGPDAPGAAEFVAELEAAGARVQVIACDAADRAAL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ARLLATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVDRVFAGKVWGAWH
MSMEG_0408|M.smegmatis_MC2_155      ARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWH
Mvan_1003|M.vanbaalenii_PYR-1       ARLFSTMRSELPPLAGIVHAAGEIGTSPLRTLDDAEMDRVFAGKVWGAVY
MMAR_3025|M.marinum_M               AKVIAEIPAQRP-LSAVVHAGGVLDDAVISSLTPERVDTVLRAKVDAAWN
MUL_2266|M.ulcerans_Agy99           AKVIAENPAQRP-LSAVVHAGGVLDDAVISSLTPERVDTVLRAKVDAAWN
Mb2074c|M.bovis_AF2122/97           AKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAAWH
Rv2048c|M.tuberculosis_H37Rv        AKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAAWH
MAV_2450|M.avium_104                AGVIAGISAERP-LSGVIHAAGVLDDAMITSLTPERIDAVLRAKVDAAWN
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LSEATSDLQ--LDFFISTSSIASVWGGFGQAAYGAANAFLDGLAWRLREQ
MSMEG_0408|M.smegmatis_MC2_155      LSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRER
Mvan_1003|M.vanbaalenii_PYR-1       LCEEVADMG--LDFFLATSSIASVWGSHGQTAYGAANAFLDGLADSLRAR
MMAR_3025|M.marinum_M               LHELTRDLD--LSAFVMFSSMAGVVGSSGQANYAAANTFVDGLAAHRRAH
MUL_2266|M.ulcerans_Agy99           LHELTRDLD--LSAFVMFSSMAGVVGSSGQANYAAANTFVDGLAAHRRAH
Mb2074c|M.bovis_AF2122/97           LHELTRDLD--VSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRRAH
Rv2048c|M.tuberculosis_H37Rv        LHELTRDLD--VSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRRAH
MAV_2450|M.avium_104                LHELTRDMN--LSAFVMFSSMAGLVGSSGQGNYAAANSFLDALAAHRRAH
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GVAGVSVNFGPWSAG-----MADAQSRARLEQRGIKTLSPADALAGLSDA
MSMEG_0408|M.smegmatis_MC2_155      GVTAVSVNFGPWAAG-----MADAESRARLEQRGVRTLSPAEALAGMADV
Mvan_1003|M.vanbaalenii_PYR-1       GIPGISVNFGPWAAG-----MADAKAREQLSRRGVKTLAPADALAGMADV
MMAR_3025|M.marinum_M               GLPAISLGWGLWDQASDMTGGMDAADRARLGREGVLALSSDEAMELFDTA
MUL_2266|M.ulcerans_Agy99           GLPAISLGWGLWDQASDMTGGMDAADRARLGREGVLALSSDEAMELFDTA
Mb2074c|M.bovis_AF2122/97           GLPAISLGWGLWDQASAMTSGLDAADLARLGREGVLALSTAEALELFDTA
Rv2048c|M.tuberculosis_H37Rv        GLPAISLGWGLWDQASAMTGGLDAADLARLGREGVLALSTAEALELFDTA
MAV_2450|M.avium_104                GLPAISLAWGLWDQASAMTGGLDAADLARLGRDGILALSSDEAMELFDTA
MLBr_00135|M.leprae_Br4923          -----------------MTASVEGADQK----------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VISAAPHPVVARVDWSRFLPLYQQAGRRGFLAELERELPAAPAQQGPAVT
MSMEG_0408|M.smegmatis_MC2_155      VAGPVQG-VVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATGAAAPAT
Mvan_1003|M.vanbaalenii_PYR-1       IAASTAHAVVARIDWATFLPVYQLQRRRAFLSQLEREVPDVPDASAPAP-
MMAR_3025|M.marinum_M               LIVNQAFLAPARIDLA---ALRAHAVAVPPMFSDLVSAPTRRQVDDALAA
MUL_2266|M.ulcerans_Agy99           LIVNQAFLAPARIDLA---ALRAHAVAVPPMFSDLVSAPTRRQIDAALAT
Mb2074c|M.bovis_AF2122/97           MIVDEPFLAPARIDLT---ALRAHAVAVPPMFSDLASAPTRRQVDDSVAA
Rv2048c|M.tuberculosis_H37Rv        MIVDEPFLAPARIDLT---ALRAHAVAVPPMFSDLASAPTRRQVDDSVAA
MAV_2450|M.avium_104                LIVDEPFLAPARIDLG---ALRAHAVAVPPMFADLVNAPTRRRVDDSLAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTR-VDAAEIREDAGFF
MSMEG_0408|M.smegmatis_MC2_155      VPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAEVTR-VDADEIRDEAGFF
Mvan_1003|M.vanbaalenii_PYR-1       -SGTTRFVEELTLAPVEQRRKLVLEYLRAAVAEVTR-VDAAEIRDEAGFF
MMAR_3025|M.marinum_M               AKSKSALAHRLHGLPEPEQHAVVLDLVRSHIATVLGTITPEAIDPDKAFQ
MUL_2266|M.ulcerans_Agy99           AKSKSALAHRLHGLPELEQHAVVLDLVRSHIATVLGTITPEAIDPDKAFQ
Mb2074c|M.bovis_AF2122/97           AKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQ
Rv2048c|M.tuberculosis_H37Rv        AKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDKAFQ
MAV_2450|M.avium_104                AKSKSALAHRLDGLPEAEQHAVLLELVRSHIATVLGSPTAEAIDPDKAFQ
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYLLGDVLGLT
MSMEG_0408|M.smegmatis_MC2_155      DLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLG
Mvan_1003|M.vanbaalenii_PYR-1       DLGMDSLMAIELRRRLEQGLGKELPVTLAMDHPHLSDAAEYVLGDVLGLS
MMAR_3025|M.marinum_M               ELGFDSLTAVEMRNRIKTVTGLSLSPTLIFDYPTPNGLANYIRAELAGAP
MUL_2266|M.ulcerans_Agy99           ELGFDSLTAVEMRNRIKTVTGLSLSPTLIFDYPTPNGLANYIRAELAGAP
Mb2074c|M.bovis_AF2122/97           DLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAGLP
Rv2048c|M.tuberculosis_H37Rv        DLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAGLP
MAV_2450|M.avium_104                ELGFDSLTAVEMRNRLKTATGLALSPTLIFDYPTPNALAGYIRTELAGAP
MLBr_00135|M.leprae_Br4923          ----------------------------------SEKLISYLKKVVVELD
MAB_3148c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          EAATAPKAATVVSTAADEPIAIVAVSCRFPG-APNPEAFWDLLSGGVDAI
MSMEG_0408|M.smegmatis_MC2_155      EQTNVRQASTVT-ARTDDPIAVVAVSCRFPG-APDPESFWELLAGGVDAI
Mvan_1003|M.vanbaalenii_PYR-1       EHT-VAQPDTPSTVRTDDPIAIVGMACRFPG-ADDTDAFWSVLAEGADLI
MMAR_3025|M.marinum_M               QEVKHTPAVRVT---GDDPIAIVGMSCRYPGGIESPDDLWDMLMARRDVL
MUL_2266|M.ulcerans_Agy99           QEVKHTPAVRVT---GDDPIAIVGMSCRYPGGIESPDDLWDMLMARRDVL
Mb2074c|M.bovis_AF2122/97           QEIKHTPAVRTT---SEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVL
Rv2048c|M.tuberculosis_H37Rv        QEIKHTPAVRTT---SEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVL
MAV_2450|M.avium_104                QETTHAPVVRAT---DDDPIAIVGMSCRFPGGVDSPEALWQMVAEGRDVL
MLBr_00135|M.leprae_Br4923          ETRARLREYEQR---ATEPVAVVGIGCRFPGGVDSPDRLWDVVSECRDVV
MAB_3148c|M.abscessus_ATCC_199      ------------------------MGCRLPGGIESPEQFWQALLRGEDFI
TH_4621|M.thermoresistible__bu      --------VNIVGDTPVNAVAVIGMACRLPGGIDSPQRLWEALLRGDDMV
                                                            :.** **   ..: :*. :    * :

Mflv_0405|M.gilvum_PYR-GCK          REVPEDR-FDIDEFYDPDPDAAGKTYTRYGGFLDHIDEFDPEFFGLSPRE
MSMEG_0408|M.smegmatis_MC2_155      REVPEDR-WDIDEFYDPDPDTPGKTYTRFGGFLDGIDGFDPEFFGISPRE
Mvan_1003|M.vanbaalenii_PYR-1       REIPDDR-FDINEFYDPDPEAAGKIYSRYGGFLDGVDGFDPEFFGISPRE
MMAR_3025|M.marinum_M               SDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFDPAFFGVGPSE
MUL_2266|M.ulcerans_Agy99           SDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFEPAFFGVGPSE
Mb2074c|M.bovis_AF2122/97           SEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSE
Rv2048c|M.tuberculosis_H37Rv        SEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSE
MAV_2450|M.avium_104                SEFPTDRGWDLAGVYNPDPDVPGTCYTRTGGFVDNVADFDPAFFGIAPSE
MLBr_00135|M.leprae_Br4923          SEFPTDRGWDVDGLFDPDPDAEGKTYTRWGAFLDDAAGFDAGFFGIAPSE
MAB_3148c|M.abscessus_ATCC_199      TEVPPAR-WDLTEYYDPESGVPGKSPSKWGAFLEDVGGFDADFFSINERE
TH_4621|M.thermoresistible__bu      TEIPVDR-WDADDYFDPEPGVPGRTVSRWGAFLDDVAGFDPEFFGISERE
                                     :.*  * :*    ::*:. . *   :: *.*::    *:. **.:   *

Mflv_0405|M.gilvum_PYR-GCK          AVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTGVFVGVAANEYAHLLS
MSMEG_0408|M.smegmatis_MC2_155      AVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYAHLLS
Mvan_1003|M.vanbaalenii_PYR-1       AVWIDPQQRLVLETAWEGLERAGYSAAALRGSRSGVYVGVGANEYSHLLS
MMAR_3025|M.marinum_M               ALAMDPQQRMFLELSWEALERAGIEPGGLRGSATGVFAGVMTQGYGMFAA
MUL_2266|M.ulcerans_Agy99           ALAMDPQQRMFLELSWEALERAGIEPGGLRGSATGVFAGVMTQGYGMFAA
Mb2074c|M.bovis_AF2122/97           ALAMDPQQRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMFAA
Rv2048c|M.tuberculosis_H37Rv        ALAMDPQHRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYGMFAA
MAV_2450|M.avium_104                ALAMDPQQRMFLELSWEALERAGIDPVKLRGSATGMFAGVYTQGYGMGAA
MLBr_00135|M.leprae_Br4923          VLAMDPQQRLMLEVSWEALEYAGIDPLSLRGSATGVFTGIFAPSYGSRDT
MAB_3148c|M.abscessus_ATCC_199      AVSIDPQHRVLLETSWQAVEHAGIDPRALAGSQTGVFVGVTHNDYQLVAA
TH_4621|M.thermoresistible__bu      AISIDPQQRLLLETSWEAMEHAGLTPADVEGSSTGVFVGLSHDDYALLTS
                                    .: ::**:*:.**  *:.:* **  .  : ** :*::.*:    *    :

Mflv_0405|M.gilvum_PYR-GCK          AESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTACSSSLVAVHQ
MSMEG_0408|M.smegmatis_MC2_155      AESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQ
Mvan_1003|M.vanbaalenii_PYR-1       GGSLDGIEAQFITGNALNVIAGRVSFTLGLEGPAVAVDTACSSSLVAVHQ
MMAR_3025|M.marinum_M               EP----VEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHM
MUL_2266|M.ulcerans_Agy99           EP----VEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHM
Mb2074c|M.bovis_AF2122/97           EP----VEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHM
Rv2048c|M.tuberculosis_H37Rv        EP----VEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHM
MAV_2450|M.avium_104                PI----AEGFRLTGQSSSVASGRVSYVLGLEGPAVSVDTACSSSLVALHM
MLBr_00135|M.leprae_Br4923          GG----LQGYGLTGTAVSVASGRVSYVLGLEGPAVSVDTACSSSLVAIHW
MAB_3148c|M.abscessus_ATCC_199      DAA-DLGGPYGFAGTNFCMASGRISYALGVHGPSLTVDAGCAAGLATVHM
TH_4621|M.thermoresistible__bu      DAG-ALEEAYGFTGSAFSMASGRIAYRLGVHGPAVTVDTACSSSLLAVHM
                                               ::*      :**::: **..**:::**:.*::.* ::* 

Mflv_0405|M.gilvum_PYR-GCK          ATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASAD
MSMEG_0408|M.smegmatis_MC2_155      ACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASAD
Mvan_1003|M.vanbaalenii_PYR-1       ACQGLQSGDCDLALAGGVNVLLSPATTIATSRARMLSPDGRCKTFDAAAD
MMAR_3025|M.marinum_M               AVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLSADGRCKAFAGAAD
MUL_2266|M.ulcerans_Agy99           AVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLSADGRCKAFAGAAD
Mb2074c|M.bovis_AF2122/97           AVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAAD
Rv2048c|M.tuberculosis_H37Rv        AVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFAAAAD
MAV_2450|M.avium_104                AVQSLRSGECDLALAGGVTVNATPDIFVEFSRMRGLSVDGRCKAYAGAAD
MLBr_00135|M.leprae_Br4923          AMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFARAAD
MAB_3148c|M.abscessus_ATCC_199      GCQSLAAGESDLVLAGGVNLVLEPRRYVGASQQRMLSPTGRCHTFTGEAD
TH_4621|M.thermoresistible__bu      ACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGMLSPTGRCHAFDVAAD
                                    .  .*  *:.*:.****. :   *      *    *:  ***:::   **

Mflv_0405|M.gilvum_PYR-GCK          GYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGASSGLTVPNGG
MSMEG_0408|M.smegmatis_MC2_155      GYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGG
Mvan_1003|M.vanbaalenii_PYR-1       GYVRGEGCGILVLKRLSDAVRDGDRIQAVIRGSAVNQDGASGGLTVPNGG
MMAR_3025|M.marinum_M               GTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQDGASNGLTAPNGP
MUL_2266|M.ulcerans_Agy99           GTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQDGASNGLTAPNGP
Mb2074c|M.bovis_AF2122/97           GTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGP
Rv2048c|M.tuberculosis_H37Rv        GTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGP
MAV_2450|M.avium_104                GTGFSEGGGMLVVERLSDARRLGHPVLAVVRGSAVNQDGASNGLTAPNGP
MLBr_00135|M.leprae_Br4923          GTGWGEGAGVVVLERLSDAQRLGHTVLAVVRGSAVNQDGASNGLTAPNGL
MAB_3148c|M.abscessus_ATCC_199      GFVMSEGCVMVLLKRLDDAVRDGDRILAVVRGTASNQDGRTVNQSTPSSE
TH_4621|M.thermoresistible__bu      GFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAANQDGRTENISTPSIQ
                                    *   .**  :::::** ** * .. : *:: .:: **** : . :.*.  

Mflv_0405|M.gilvum_PYR-GCK          AQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQAAAAAYAGARD
MSMEG_0408|M.smegmatis_MC2_155      AQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQAAAAAYGAGRD
Mvan_1003|M.vanbaalenii_PYR-1       AQQRVIAAALTRAGLSGSDIDYLEAHGTGTSLGDPIEVQAAGAVLGAGRD
MMAR_3025|M.marinum_M               SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRG
MUL_2266|M.ulcerans_Agy99           SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRG
Mb2074c|M.bovis_AF2122/97           SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRG
Rv2048c|M.tuberculosis_H37Rv        SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRG
MAV_2450|M.avium_104                SQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRG
MLBr_00135|M.leprae_Br4923          AQQRVIQAALTNAGLSSADVDVVEAHGTATTLGDPIEAQALLATYGQGRP
MAB_3148c|M.abscessus_ATCC_199      AQAAACRTALAVAGVEADTVGLIEAHGTGTPVGDPIEYTGLAQVYGVDGP
TH_4621|M.thermoresistible__bu      AQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDPIEYNSLTQVYGKTGP
                                    :*     :.*: **:    :. :*.***.*.:*****  .   . .    

Mflv_0405|M.gilvum_PYR-GCK          AD----RPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHETLPQSLHFDT
MSMEG_0408|M.smegmatis_MC2_155      AD----RPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSLHFEN
Mvan_1003|M.vanbaalenii_PYR-1       PD----RPLLMGSVKTNVGHLESASGVAGLIKVVLSLQHEMLPRHLHFKT
MMAR_3025|M.marinum_M               SAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVLPATLHVDV
MUL_2266|M.ulcerans_Agy99           SAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVLPATLHVDV
Mb2074c|M.bovis_AF2122/97           EP---GEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDV
Rv2048c|M.tuberculosis_H37Rv        EP---GEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDV
MAV_2450|M.avium_104                QP------LWLGSIKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDE
MLBr_00135|M.leprae_Br4923          AD----QPLWVGSIKSNMGHTQAAAGVAGVIKMVQAMRHHVMPATLHVDE
MAB_3148c|M.abscessus_ATCC_199      CA--------VGSVKTNFGHTMSAAGALGLMKIVLAVEHGVVPPNLHFTG
TH_4621|M.thermoresistible__bu      CA--------LTSVKTNFGHAESAAGALGMMKAILALQHGVVPQNLHFTR
                                              : *:*:*.**  :*:*. *::* : ::.*  :*  **.  

Mflv_0405|M.gilvum_PYR-GCK          PSPHIPWDSLPVRVVDTAMPWQ---PNGRPRRAGVSSFGFTGTNAHVLIE
MSMEG_0408|M.smegmatis_MC2_155      PSPHIPWDALPVRVIDEPVPWQ---TNGRVRRAGVSSFGFTGTNAHVLVE
Mvan_1003|M.vanbaalenii_PYR-1       PSPHIPWDRLAVRVVAEPTPWR---ADGRPRRAGVSSFGFSGTNAHVVLE
MMAR_3025|M.marinum_M               PSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAHVIVE
MUL_2266|M.ulcerans_Agy99           PSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAHVIVE
Mb2074c|M.bovis_AF2122/97           PSPHVDWSAGAVELLTAPRVWP---AGARTRRAGVSSFGISGTNAHVIIE
Rv2048c|M.tuberculosis_H37Rv        PSPHVDWSAGAVELLTAPRVWP---AGARTRRAGVSSFGISGTNAHVIIE
MAV_2450|M.avium_104                PSPHVDWSAGAVSLLTEAQPWP----GERPRRAGVSSFGISGTNAHVIIE
MLBr_00135|M.leprae_Br4923          PSPRVDWTTGAVSVLTEARDWS---VEGRPRRAGVSSFGISGTNAHVILE
MAB_3148c|M.abscessus_ATCC_199      IPDKLAPVKTNLFVPQTVIPWP--GKAQGPRRAGVSAYGMSGSNVHAVVE
TH_4621|M.thermoresistible__bu      LPDEMAAIETNLFVPQATTLWP--VREGCPRRAAVSSYGMSGTNVHAVLE
                                     . .:      : :      *         ***.**::*::*:*.*.::*

Mflv_0405|M.gilvum_PYR-GCK          EAPTDLAGPTEPTAPAE-PVDEDAAADP-APAPVEVLPLSARSPEALVAL
MSMEG_0408|M.smegmatis_MC2_155      EAPPQLH-----TADAA-PVEPAATAEAGTDDSPQVLALSARSPEALVEL
Mvan_1003|M.vanbaalenii_PYR-1       EPPAQSADLRQPPTDGK--DGAAGLESATAPEPAGVLPISARSPEALTAL
MMAR_3025|M.marinum_M               AAP-----------------RVEVGGSSGGAVPVVPWVVSAKSGSALGAQ
MUL_2266|M.ulcerans_Agy99           AAP-----------------RVEVGGSSGGAVPVVPWVVSAKSGSALGAQ
Mb2074c|M.bovis_AF2122/97           AVP-----------------VVPRR-EAGWAGPVVPWVVSAKSESALRGQ
Rv2048c|M.tuberculosis_H37Rv        AVP-----------------VVPRR-EAGWAGPVVPWVVSAKSESALRGQ
MAV_2450|M.avium_104                AVP-----------------AVEPAHADAPALPVLPWVVSAKSAAALRAQ
MLBr_00135|M.leprae_Br4923          EAP--------------TPVEASYSTADQQRLSVVPWVVSGRSTAALMAQ
MAB_3148c|M.abscessus_ATCC_199      QAP--------------PVESSTPPAVESPLGSQLIFPVSSTSAEELRRT
TH_4621|M.thermoresistible__bu      QAP--------------EPVQRPEESADTDAAGPLVFALSSTSAEELRRT
                                      *                                   :*. *   *   

Mflv_0405|M.gilvum_PYR-GCK          AQRYETWLTAHP-EADLADVCRTAGTGRSHFEHRAALVVDSVESARIALT
MSMEG_0408|M.smegmatis_MC2_155      ARRYDDWLSATP-GLDIADVCHTAGVGRSHFEYRAALVVDSVERAREGLA
Mvan_1003|M.vanbaalenii_PYR-1       ARRYESWLTAHP-DADIADVCYTAGAGRSHFEHRAALVVDSVDGARDLLA
MMAR_3025|M.marinum_M               AARLAAHVRSHD-ELDVADVGWSLAG-RSTFEHRAVVLGVDRDGLLAGLD
MUL_2266|M.ulcerans_Agy99           AARLAAHVRSHD-ELDVADVGWSLAG-RSTFEHRAVVLGADRDGLLAGLD
Mb2074c|M.bovis_AF2122/97           AARLAAYVRGDD-GLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLLAGLD
Rv2048c|M.tuberculosis_H37Rv        AARLAAYVRGDD-GLDVADVGWSLAG-RSVFEHRAVVVGGDRDRLLAGLD
MAV_2450|M.avium_104                AARLAEYVRAQG-ELDIADVGWTLAG-RATFEHRAVVVGGDRDRLLAGLD
MLBr_00135|M.leprae_Br4923          ASRLAFYVQADP-EVDPVDVGCALAA-RSVFEHRAVVVGESREQLIAGLA
MAB_3148c|M.abscessus_ATCC_199      AARLADWVAERP-EVAPGDVGYTLARRRAHRSVRTAVVADGADELIDALR
TH_4621|M.thermoresistible__bu      AGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVRTTVIADGVEALTAGLR
                                    * *    :          *:  : .  *:    *:.::  . :     * 

Mflv_0405|M.gilvum_PYR-GCK          DLAQNRLR-PGVVRGEHLNHPTTAWMFTGQGSQYPGMARELFDTEPVFAD
MSMEG_0408|M.smegmatis_MC2_155      ALAEGRTP-AGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVFAQ
Mvan_1003|M.vanbaalenii_PYR-1       GLAEDRLG-PGAVRGVCGDPPKTAWLFTGQGSQYPGMARELFDTEPVFRD
MMAR_3025|M.marinum_M               ELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHAGYPVFAE
MUL_2266|M.ulcerans_Agy99           ELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHAGYPVFAE
Mb2074c|M.bovis_AF2122/97           ELAGDQLG-GSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAE
Rv2048c|M.tuberculosis_H37Rv        ELAGDQLG-GSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVFAE
MAV_2450|M.avium_104                ELAADDPA-ASIIRGVATPAGKTVFVFPGQGSQTLGMGRQLHAGYPVFAE
MLBr_00135|M.leprae_Br4923          GLAVGESG-AGVAIGQAAPLGKTVVVFPGQGAQRIGMGRELCSQLPVFAE
MAB_3148c|M.abscessus_ATCC_199      GVAEGDAP---YPAAVAQDDRGPVWLFSGQGSQWAGMGAELLGKEPVFAE
TH_4621|M.thermoresistible__bu      EVADGDAP---YQPAVGMDDKAPVWVFSGQGSQWAGMGAELLATEQVFAA
                                     :* .         .       .. :*.***:*  **.  *     **  

Mflv_0405|M.gilvum_PYR-GCK          TVTRCADAVADLLPRPLLDVMFAGGREAGVPPTETLRHTSFAQPALFAVE
MSMEG_0408|M.smegmatis_MC2_155      TVRQCAEAVADMLPRPLLDVLFATDRET----ADLLQHTSFAQPALFAVE
Mvan_1003|M.vanbaalenii_PYR-1       TVTRCAEAIGDTLPRPLLEVLFDTDGDN----GQTLRHTSYAQPALFAIE
MMAR_3025|M.marinum_M               AFNTVVGELDRHLLRPLREVIWGHDENL-------LNTTEFAQPALFAVE
MUL_2266|M.ulcerans_Agy99           AFNTVVGELDRHLLRPLREVIWGHDENL-------LNTTEFAQPALFAVE
Mb2074c|M.bovis_AF2122/97           AFNTVVGELDRHLLRPLREVMWGHDENL-------LNSTEFAQPALFAVE
Rv2048c|M.tuberculosis_H37Rv        AFNTVVGELDRHLLRPLREVMWGHDENL-------LNSTEFAQPALFAVE
MAV_2450|M.avium_104                AFDAVVAELDRHLLRPLRDVIWGDDENV-------LNSTEFAQPALFAVE
MLBr_00135|M.leprae_Br4923          EFDAVTGELDRHMRLPLRDVVWGADAGL-------LDSTEFAQPALFAVE
MAB_3148c|M.abscessus_ATCC_199      TIARLEPLIHAESGFSVTDAISAPETVTG---------IDRVQPTLFAMQ
TH_4621|M.thermoresistible__bu      KIAEIEPLVARESGFSVTEAMTASETVTG---------IDRVQPTLFAIQ
                                     .      :      .: :.:                  . .**:***::

Mflv_0405|M.gilvum_PYR-GCK          MGLARLWQSWGIVPDVVLGHSVGQYAAACVAGVFSLEDGARLMAERGRLF
MSMEG_0408|M.smegmatis_MC2_155      MGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRMF
Mvan_1003|M.vanbaalenii_PYR-1       MGLARLWQARGIEPDVVLGHSVGQYAAACVAGVFGLEDGARLVADRGRLF
MMAR_3025|M.marinum_M               VALYRLLESWGVRPDFVMGHSVGELSAAHVAGVLSLENAAVLVAARGRLM
MUL_2266|M.ulcerans_Agy99           VALYRLLESWGVRPDFVMGHSVGELSAAHVAGVLSLENAAVLVAARGRLM
Mb2074c|M.bovis_AF2122/97           VALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLM
Rv2048c|M.tuberculosis_H37Rv        VALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGRLM
MAV_2450|M.avium_104                VALFRLLESWGVRPDFVMGHSIGELSAAHVAGVLSLQNAAVLVAARGRFM
MLBr_00135|M.leprae_Br4923          VALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPADAAMLVVARGRLM
MAB_3148c|M.abscessus_ATCC_199      VSLAATLASYGVRPGAVIGHSMGEVAAAVVSEALSLEDGVKVICRRSQLM
TH_4621|M.thermoresistible__bu      VALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLEDGVKVICRRSRLC
                                    :.*       .: *. *:***:*: :** *: .:.  :.. ::  *.:: 

Mflv_0405|M.gilvum_PYR-GCK          GSLPEGGRMVAVFADAKRVEQVAAD--FPRVSVGAYNGPN-TVLSGPGED
MSMEG_0408|M.smegmatis_MC2_155      GSLPEGGRMVAVFADAEHVEQVAGE--FPRVSVGAYNGPN-TVLSGPGED
Mvan_1003|M.vanbaalenii_PYR-1       GGLPVGGRMVAVFTDAEVVEDFADE--FPQVSVAAYNGPN-TVLAGPASD
MMAR_3025|M.marinum_M               QALPDGGAMIAVQATEQEVLPLLG----AQVSIAAINGPASVVISGAQDA
MUL_2266|M.ulcerans_Agy99           QALPDGGAMIAVQATEQEVLPLLG----AQVSIATINGPASVVISGAQDA
Mb2074c|M.bovis_AF2122/97           QALPAGGAMVAVQAAEEEVRPLLS----AEVDIAAVNGPASLVISGAQNA
Rv2048c|M.tuberculosis_H37Rv        QALPAGGAMVAVQAAEEEVRPLLS----AEVDIAAVNGPASLVISGAQNA
MAV_2450|M.avium_104                QALPEGGAMIAVQATEAQVRPLLG----PDVGIAAVNGPAAVVISGDHDA
MLBr_00135|M.leprae_Br4923          QSMPAGGTMWAVAASEDEVVSLLG----EGVGIAAINAPESVVISGPQAA
MAB_3148c|M.abscessus_ATCC_199      LRISGAGAMASVDLPAQQVVSELADRDIHDVVLAVVASPQSTVVGGATET
TH_4621|M.thermoresistible__bu      LRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPESTVIGGATDT
                                      :. .* * ::      *           * :..  .*   *:.*    

Mflv_0405|M.gilvum_PYR-GCK          LEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFESYAAQLQFAAPTL
MSMEG_0408|M.smegmatis_MC2_155      LEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDEFEAYAAQFQFAAPTL
Mvan_1003|M.vanbaalenii_PYR-1       LEQIVAGCSGEGIRTTWLDTSHAFHSALLDPVLDEFESCAARLAYAAPTR
MMAR_3025|M.marinum_M               VSAVAEQLRADGRRVHRLAVSHAFHSPLMDPMIDEFATVAGELTVNAPTI
MUL_2266|M.ulcerans_Agy99           VSAVAEQLRADGRRVHRLAVSHAFHSPLMDPMIDEFATVAGELTVNAPTI
Mb2074c|M.bovis_AF2122/97           VAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTI
Rv2048c|M.tuberculosis_H37Rv        VAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRPTI
MAV_2450|M.avium_104                AVAIAERLRAEGHRVHRLSVSHAFHSPLMEPMIDEFGTVAAGLAIDKPVI
MLBr_00135|M.leprae_Br4923          VSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEEFVRVAAQVEVRKPQI
MAB_3148c|M.abscessus_ATCC_199      VRQLIAEWSDRGLMAREVAVDVASHSPQVDPILDDLADALEDLTPRTPVV
TH_4621|M.thermoresistible__bu      VRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILADLQPMTPTV
                                       :       *     : .. * **  ::*:::::      .    *  

Mflv_0405|M.gilvum_PYR-GCK          PLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEI
MSMEG_0408|M.smegmatis_MC2_155      PLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEI
Mvan_1003|M.vanbaalenii_PYR-1       PLVCNRTGAVVTGPGVIDAQYWRRHARQPVQFAESVRTLADLGCSVLMEI
MMAR_3025|M.marinum_M               GIISNLTG-QLAGEDFGSAAYWKRHVRDAVRFADSIRFAQSAGAARFLEV
MUL_2266|M.ulcerans_Agy99           GIISNLTG-QLAGEDFGSAAYWKRHVRDAVRFADSIRFAQSAGAARFLEV
Mb2074c|M.bovis_AF2122/97           GVISNVTG-QLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEV
Rv2048c|M.tuberculosis_H37Rv        GVISNVTG-QLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFLEV
MAV_2450|M.avium_104                PIISNLTG-QPAADDFGSPEYWKCHVRDAVRFADSVRFAQSAGATRFLEV
MLBr_00135|M.leprae_Br4923          GLVSNVTG-ELAGPDFGSPQYWGEHVSRAVRFVDSARHLQTLGATHFIES
MAB_3148c|M.abscessus_ATCC_199      PLYS-SVSFDPRERPIMDADYWVDNLRHTVRFAAAVQAALDDGYRVFGEL
TH_4621|M.thermoresistible__bu      PYYS-ATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAALEDGFRVFGEL
                                       .  ..         .. **  :    *:*. : :     *   : * 

Mflv_0405|M.gilvum_PYR-GCK          GPQPVLTGAAVQVWPEHLAAPR--AIASLRKGVADRRQIADALAAAYIGG
MSMEG_0408|M.smegmatis_MC2_155      GPQPVLTGAAVQVWPEHMAAPR--AVASLRKGVADRRQIADALASAYVGG
Mvan_1003|M.vanbaalenii_PYR-1       GPQPFLIAAALRVWPESAATPR--AIPSLRKGPDARRQLAEAVAAAYIAG
MMAR_3025|M.marinum_M               GPSSGLTASIEEVLSDAAVTNPVATASALRKDRPEPVSLVSAVAGVFVAG
MUL_2266|M.ulcerans_Agy99           GPSIGLTASIEEVLSDAAVTNPVATASALRKDRPEPVSLVSALAGVFVAG
Mb2074c|M.bovis_AF2122/97           GPSGGLVASIEESLPDVAVT----TMSALRKDRPEPATLTNAVAQGFVTG
Rv2048c|M.tuberculosis_H37Rv        GPSGGLVASIEESLPDVAVT----TMSALRKDRPEPATLTNAVAQGFVTG
MAV_2450|M.avium_104                GPSSGLTAAIEETLADAPVV----TVSALRKDRPEPVALVNAVAQGWVCG
MLBr_00135|M.leprae_Br4923          GPSSGLMGAIEQSLAPAEAV----VVSMMGKDRPELASVLGAAGQLFATG
MAB_3148c|M.abscessus_ATCC_199      APHPLLVYPAEQTARSLDIP--MVALAGMRREQELPHGLRDFVGDLYTAG
TH_4621|M.thermoresistible__bu      SPHPLLTRAVEQTARGLDMP--VAALPAMRREQEMPHGVRTMVGDLFAAG
                                    .*   *  .  .            . . : :       :    .  :  *

Mflv_0405|M.gilvum_PYR-GCK          HKPDFAALHEQR-GVRLELPTYPFQRRRFWPK---SAGMAIDGRVGASAG
MSMEG_0408|M.smegmatis_MC2_155      HRPDFAAVHRQP-RRPVELPTYPFQRRRFWPK---ASSIAVDG---GTAA
Mvan_1003|M.vanbaalenii_PYR-1       HRLDFTGHDGGP-HRRLPLPTYPFQHRSYWPK---TAGIRSDG----SSG
MMAR_3025|M.marinum_M               TAVDWRAVVGQS--NFVELPTYAFERRRFWLS-GDAVAADAAGLGLQAGE
MUL_2266|M.ulcerans_Agy99           TAVDWRAVVGQS--HFVELPTYAFERRRFWLS-GDAVPADAAGLGLQAGE
Mb2074c|M.bovis_AF2122/97           MDLDWRAVVGEA--QFVELPTYAFQRRRFWLS-GDGVAADAASLGLAASE
Rv2048c|M.tuberculosis_H37Rv        MDLDWRAVVGEA--QFVELPTYAFQRRRFWLS-GDGVAADAAGLGLAASE
MAV_2450|M.avium_104                MDVDWRGALGTG--HLVDLPTYAFDRRRFWLS-GDGAASDAAGLGLAAGD
MLBr_00135|M.leprae_Br4923          MPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPGTDGTASVSGLGLGSTE
MAB_3148c|M.abscessus_ATCC_199      GAVDFSVLYPTG--QLVDVPLPSWTRRSYLLD--LSAQAQQGHGTHTVAV
TH_4621|M.thermoresistible__bu      AAVDFAALYPSG--RLVDAPLPTWTRRKLVLS--RENGEQQTRGGCTITV
                                       ::           :  *  .: :*                       

Mflv_0405|M.gilvum_PYR-GCK          SGILGSGKD-LASGD-SVYTSRLSVKTQPWLSDHVIYGTVVVPGATYAAM
MSMEG_0408|M.smegmatis_MC2_155      SGILGSGKD-LASGD-TIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAM
Mvan_1003|M.vanbaalenii_PYR-1       SGLLGSAQD-LASGD-IVHTSRLSVKTQPWLSDHVIYGTVVVPGATYAAM
MMAR_3025|M.marinum_M               HALLGAVVELPASGG-VVLTGRLSLAAQGWLADHAVGGVVIFPGAGFVEL
MUL_2266|M.ulcerans_Agy99           HALLGAVVELPASGG-VVLTGRLSLAAQGWLADHAVGGVVIFPGAGFVEL
Mb2074c|M.bovis_AF2122/97           HALLGAVIDLPASGG-VVLTGRLSPSVQGWLADHSVAGVTIFPGAGFVEL
Rv2048c|M.tuberculosis_H37Rv        HALLGAVIDLPASGG-VVLTGRLSPSVQGWLADHSVAGVTIFPGAGFVEL
MAV_2450|M.avium_104                HALLGAVVELPASGG-VLLTGRLSPASQGWLADHAVGGVVLFPGAGFVEL
MLBr_00135|M.leprae_Br4923          HALLGAVVERPDSGG-VVLTGRLSLANQPWLADHVIGGVVLFPGAGFVEL
MAB_3148c|M.abscessus_ATCC_199      HPLLGAHVRLAEEPERHIWQADVGTVGQPWIADHQVRHVAVYPGAAYCEM
TH_4621|M.thermoresistible__bu      HPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAAYCEM
                                      :**:      .    :  . :.   * *::** :  ..  *** :  :

Mflv_0405|M.gilvum_PYR-GCK          ALAAVGTP--AHAKDVFFYEPIILPEKSSREVQLTVHPSVDGESK-FQVH
MSMEG_0408|M.smegmatis_MC2_155      ALAAVGTP--ARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQIH
Mvan_1003|M.vanbaalenii_PYR-1       ALAAMPTP--ARVQEVFFYEPIILGDKDSREVQLMLHRTDDADGWTFEVH
MMAR_3025|M.marinum_M               AIRAGDEVGCRVVDELTLAAPLVLPSGGSVAVQVVVGSPDDSGARAVSVY
MUL_2266|M.ulcerans_Agy99           AIRAGDEVGCRVVDELTLAAPLVLPSGGSVAVQVVVGSPDDSGARAVSVY
Mb2074c|M.bovis_AF2122/97           AIRAGDEVGCGVVDELTLAAPLVLPASGSVAVQVVVNGPDESGVRGVSVY
Rv2048c|M.tuberculosis_H37Rv        AIRAGDEVGCGVVDESTLAAPLVLPASGSVAVQVVVNGPDESGVRGVSVY
MAV_2450|M.avium_104                AIRAGDEVGCGIIDELNLAAPLVLPAGGSVAIQVVVDGPDDSGARAVSVF
MLBr_00135|M.leprae_Br4923          VIRAGDEVGCAGVEELVLAAPLVLHPGSGVQVQVVVAAADESSRRAVSVY
MAB_3148c|M.abscessus_ATCC_199      ALSAAAAVFG-EGSAVQSISFEQLLTLGESTPISATATAKSADILEFVVE
TH_4621|M.thermoresistible__bu      ALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAVEPGTLEFAVE
                                    .: *                   :              .       . : 

Mflv_0405|M.gilvum_PYR-GCK          SRPYGERGAE-WALNAEGVVASGVGDSPAAAGDLEDPVDE----AIERLN
MSMEG_0408|M.smegmatis_MC2_155      SRPYGERGAD-WSLNAEGTVDTAGSDPDAAADEQSDPVDE----VIERLE
Mvan_1003|M.vanbaalenii_PYR-1       SRPYGDRDAD-WSRNASGTVAAGVG--DAAPDAAADPVDN----AIERLT
MMAR_3025|M.marinum_M               SR--GDAGSD-WVLHAEGSLGSGSP--EPATDLSTWPPVG----AVE---
MUL_2266|M.ulcerans_Agy99           SR--GDAGSD-WVLHAEGSLGSGSP--EPATDLSTWPPVG----AVE---
Mb2074c|M.bovis_AF2122/97           SR--GDVGTG-WVLHAEGALRAGSA--EPTADLAMWPPAG----AVP---
Rv2048c|M.tuberculosis_H37Rv        SR--GDVGTG-WVLHAEGALRAGSA--EPTADLAMWPPAG----AVP---
MAV_2450|M.avium_104                SR--ADAGAG-WLLHAEGVLRAGSA--QPATDLSAWPPVG----AVP---
MLBr_00135|M.leprae_Br4923          SR--GDQSHGGWLLNAEGLLEVDAA--EATVDLSLWPPEG----AES---
MAB_3148c|M.abscessus_ATCC_199      THDEGDVVKR-----ATAVLGNGGDVDMPIAYDLSALRAEHPHR------
TH_4621|M.thermoresistible__bu      TAKDGEHERR-----ATAVLGAADDTEPPQAHDIDALLAEHPTR------
                                    :   .:         * . :        .                     

Mflv_0405|M.gilvum_PYR-GCK          RMRPQELFETFADLELAWGPTWSGSLKSLWLGEGE--AIGDILVGAELAE
MSMEG_0408|M.smegmatis_MC2_155      RMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGE--AVGDILVGAELAE
Mvan_1003|M.vanbaalenii_PYR-1       RTRPQQLFDAFADNDLAWGPAWCSSLRSLWVGTGE--AVGDIAVGAELGE
MMAR_3025|M.marinum_M               -VENADGYQQLAERGYGYGPAFRG-LNAMWRRGDE--VFAEVALPADAGV
MUL_2266|M.ulcerans_Agy99           -VENADGYQQLAERGYGYGPAFRG-LNAMWRRGDE--VFAEVALPADAGV
Mb2074c|M.bovis_AF2122/97           -VEVADGYQQLAERGYGYGPAFRG-LTAMWRRGDE--VFAEVALPADAGV
Rv2048c|M.tuberculosis_H37Rv        -VEVADGYQQLAERGYGYGPAFRG-LTAMWRRGDE--VFAEVALPADAGV
MAV_2450|M.avium_104                -VDLGDGYEQLAERGYRYGPAFRG-LTSMWRRGDE--IFAEVNLPTDAGV
MLBr_00135|M.leprae_Br4923          -VDISDAYPQLAERGYAYGPAFQG-LVAIWRRGSE--LFAEVVAPT--GV
MAB_3148c|M.abscessus_ATCC_199      -ESGDDLRASFDERGVQYGPAFQGLAAAYRGDETVRSVLAEVTLPRDVRA
TH_4621|M.thermoresistible__bu      -IEGDELRQWFDQRGVQFGPAFTGLTAARIPEGTVTSVLAEVGLPGQIRS
                                         :    : :    :**:: .   :          ..::        

Mflv_0405|M.gilvum_PYR-GCK          QLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYGQVSLQEK
MSMEG_0408|M.smegmatis_MC2_155      QLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLAEK
Mvan_1003|M.vanbaalenii_PYR-1       HLGREPIHPVLLDLCTGIAGAALLAAAAQTDADPELFLPLRYGRVEVRER
MMAR_3025|M.marinum_M               SVSGFGIHPVMLDAALHAVILASDGADDFGVPEGSVLVPFAWQGVTLHAA
MUL_2266|M.ulcerans_Agy99           SVSGFGIHPVMLDAALHAVILASDGADDFGVPEGSVLVPFAWQGVTLHAA
Mb2074c|M.bovis_AF2122/97           SVTGFGVHPVLLDAALHAVVLSAESAERG---QGSVLVPFSWQGVSLHAA
Rv2048c|M.tuberculosis_H37Rv        SVTGFGVHPVLLDAALHAVVLSAESAERG---QGSVLVPFSWQGVSLHAA
MAV_2450|M.avium_104                STTGFGVHPVMLDAALHAVMLASDGDDLP---AGSMLVPFSWQRVSLHAA
MLBr_00135|M.leprae_Br4923          VVDGMGMHPALLDAVLHALGLAIENTQAT----TEMRLPFCWRGVSLHAG
MAB_3148c|M.abscessus_ATCC_199      QQGSYIVHPALLDACFQSVIALPDVQEASK---DALPLPKGVRSLHAYES
TH_4621|M.thermoresistible__bu      QQAPYGIHPALLDACFQSVAAHPDVQGAG----SGLLLPLGVRRLQAFGP
                                          :**.::*                      : :*     :     

Mflv_0405|M.gilvum_PYR-GCK          MPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVREFTVKRAPREA
MSMEG_0408|M.smegmatis_MC2_155      MPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREA
Mvan_1003|M.vanbaalenii_PYR-1       MPRRFYCRARWQTGGIDSETQVFDLDFLDHDGRNLGGIREFTVKRAPREA
MMAR_3025|M.marinum_M               GASAVRARIAPAG------PSAVSIELSDGLGLPVLSVASMLARPVTDQQ
MUL_2266|M.ulcerans_Agy99           GASAVRARIAPAG------PSAVSIELSDGLGLPVLSVASMLARPVTDQQ
Mb2074c|M.bovis_AF2122/97           GASAVRARIAPVG------PSAVSIELADGLGLPVLSVASMLARPVTDQQ
Rv2048c|M.tuberculosis_H37Rv        GASAVRARIAPVG------PSAVSIELADGLGLPVLSVASMLARPVTDQQ
MAV_2450|M.avium_104                GAAAVRARIVPVS------PSAVSIELADGLGLPVLSVASMVARPVTDQQ
MLBr_00135|M.leprae_Br4923          GAGRVRARFTSAG------ADAIAVDIADSAGLPVLTVRSLVTRAMTAEQ
MAB_3148c|M.abscessus_ATCC_199      ARATQYCYTRVTKVV--GNEVEADIDLLDETGSVLIAVRGFRFGTGSSDD
TH_4621|M.thermoresistible__bu      TRGARYCYARVTDAD--GSKAEADLDVLDEHGNVLLRVQGLLMGGAAADG
                                          .                 ::  *  *  :  :  :     . : 

Mflv_0405|M.gilvum_PYR-GCK          LLRGLGGDA---TRLLYTLGWHEVPVPESGDGAAP-QGTWLIGGFDELAV
MSMEG_0408|M.smegmatis_MC2_155      LLRGLGGDA---TRLLYTLGWHEVPPPPSADDAV---GTWLIAGFDELAA
Mvan_1003|M.vanbaalenii_PYR-1       LLRGLGADA---TRLIYRVGWRETSPPVRDDGALGPSSTWLVAGLDALAD
MMAR_3025|M.marinum_M               LRAAVSGAG---PDRLFGVDWTAQPSAELQP--------VPVRIWGAVES
MUL_2266|M.ulcerans_Agy99           LRAAVSGAG---PDRLFGVDWTAQPSAELQP--------VPVRIWGTVES
Mb2074c|M.bovis_AF2122/97           LRAAVSSSG---PDRLFEVTWSPQPSAAVEP--------LPVCAWGTTED
Rv2048c|M.tuberculosis_H37Rv        LRAAVSSSG---PDRLFEVTWSPQPSAAVEP--------LPVCAWGTTED
MAV_2450|M.avium_104                LLAAVSNSG---PDRLFELIWSAQPSTAVQP--------VSLLNWGATEL
MLBr_00135|M.leprae_Br4923          LRTAVTAAGGALEQGPMDLVWSPIPLSSDGHGGGL----PSVVSWADYCA
MAB_3148c|M.abscessus_ATCC_199      EQRDQLLNN-----RLLAIEWQQQRLPESVSGAPRRWLLVSTGESVDPWA
TH_4621|M.thermoresistible__bu      DDRDRVLGE-----RLLTIEWQRRDLPEADS-AAGKWLLVSTSATADVSA
                                                      : *     .                       

Mflv_0405|M.gilvum_PYR-GCK          SVPGCIPADR----------------TNPESLRQLLTDAHGRGLPFSGVV
MSMEG_0408|M.smegmatis_MC2_155      KVPGCVPIDRN---------------TDLQVLGEVLSQAHARGAGFSGVV
Mvan_1003|M.vanbaalenii_PYR-1       DVPGSIRIGFDRIWDPDRDGRVVLDPADDEHWRRLFALADERRAPVAGVV
MMAR_3025|M.marinum_M               EGDDDPG---------------------------------------ASVV
MUL_2266|M.ulcerans_Agy99           EGDDDPG---------------------------------------ASVV
Mb2074c|M.bovis_AF2122/97           S---------------------------------------------AAVV
Rv2048c|M.tuberculosis_H37Rv        S---------------------------------------------AAVV
MAV_2450|M.avium_104                DATDTDSDSGR-----------------------------------FAVL
MLBr_00135|M.leprae_Br4923          GRGNDTG----------------------------------------VVV
MAB_3148c|M.abscessus_ATCC_199      AELIDSLKVRES---------EVSLIQWRPNTDRVAALKLLYDQLESGTF
TH_4621|M.thermoresistible__bu      TRLSDALKQAGA---------ESTSMCWPQQADHADNVDRFRAGIADG-V
                                                                                     .

Mflv_0405|M.gilvum_PYR-GCK          WRAARSDGDESD--AEVAARLEAEIAELLGAVHTVQGGEVKLPGGLWIVT
MSMEG_0408|M.smegmatis_MC2_155      WRCATPGRKESGSASAESARLEAEITNLLSAVHAAQGPSVKLPGGLWIVT
Mvan_1003|M.vanbaalenii_PYR-1       LGVTGRARPEEPS-ADFAARLEAQIRDVLGAVHSLSALGAKPAAGLWIVT
MMAR_3025|M.marinum_M               FESVPQAG-------EVVAGVYAATAAVLEVLRSWLSR--DGAGQLVITT
MUL_2266|M.ulcerans_Agy99           FESVPQAG-------EVVAGVYAATAAVLEVLRSWLSR--DGAGQLIITT
Mb2074c|M.bovis_AF2122/97           FESVPLAG-------DVVAGVYAATSSVLDVLQSWLTR--DGAGVLVVMT
Rv2048c|M.tuberculosis_H37Rv        FESVPLAG-------DVVAGVYAATSSVLDVLQSWLTR--DGAGVLVVMT
MAV_2450|M.avium_104                FESAPVAG-------DVVTEVYAATRAVLPVLQSWLAR--DGAGTLVVST
MLBr_00135|M.leprae_Br4923          WEFGSASAGAQAP-VDSVAAVYSATHAALQVLQFWFGQ--DRAGTLVVLT
MAB_3148c|M.abscessus_ATCC_199      DGVLVVTAPGSEGGADRVVLQGADQVRHLVRITRELVDLPGEPPRLFVVT
TH_4621|M.thermoresistible__bu      TGVVVLTGPKNGNPDDAAARRGSDYVRHLVRITRELAEIDGDAPRLFVVT
                                                      .   :     *  :          .  * : *

Mflv_0405|M.gilvum_PYR-GCK          ERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLVDCDGSPQAVQAL
MSMEG_0408|M.smegmatis_MC2_155      EHGVACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDLL
Mvan_1003|M.vanbaalenii_PYR-1       ERAVAAEAGEPVDPVQSALWGLGRTLIAEEPGLRCLLVDLDGSEDAGPAL
MMAR_3025|M.marinum_M               RGAVALPDEDVTDLAGSAVWGLVRSAQTEHPG-RIVLVDTD-AQLDEHAV
MUL_2266|M.ulcerans_Agy99           RGAVALPDEDVTDLAGSAVWGLVRSAQTEHPG-RIVLVDTD-AQLDEHAV
Mb2074c|M.bovis_AF2122/97           RGAVALPGEDVTDLAGAAVWGLVRSAQTEHPG-RIVLVDSD-APLDDSAL
Rv2048c|M.tuberculosis_H37Rv        RGAVALPGEDVTDLAGAAVWGLVRSAQTEHPG-RIVLVDSD-APLDDSAL
MAV_2450|M.avium_104                RGAMTLPGEDVTDLAGAAVWGLVRSAQTEHPG-RIVLVDTD-APLDADAV
MLBr_00135|M.leprae_Br4923          RGAVGLVGEGISDLAAAAVWGMVRSAQSEHSG-KIVLIDTD-SAVD---V
MAB_3148c|M.abscessus_ATCC_199      RNAQTVVDGDITNLEQAGLRGLVRVIGAEYPHLRVTHIDVDRHTAAQNVA
TH_4621|M.thermoresistible__bu      RGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIADDADLDRVA
                                    . .         :   :.: *: *    * .  :   :*           

Mflv_0405|M.gilvum_PYR-GCK          AALLSTP-VDEPELAVRQGKLLASRLLPWSRSGH----LTVPRG-GDYVL
MSMEG_0408|M.smegmatis_MC2_155      AALLAAPGIQEPEIAVRQGKLLASRLLPWARSGH----LTLPRG-GDFVL
Mvan_1003|M.vanbaalenii_PYR-1       ARLLGAP-GDEPELALRQGRLLVPRLLPWSRSGQ----LAIPRG-TDYVL
MMAR_3025|M.marinum_M               AAVLAAG---EPQVLWRNGEVYTARVHGSRAVAG----LLVPPGDGPWRL
MUL_2266|M.ulcerans_Agy99           AAVLAAG---EPQVLWRNGEVYTARVHGSRAVAG----LLVPPGDGPWRL
Mb2074c|M.bovis_AF2122/97           AAVVTTG---EPQVLWRRGEVYTARVHGSRAVGG----LLVPPSDRPWRL
Rv2048c|M.tuberculosis_H37Rv        AAVVTTG---EPQVLWRRGEVYTARVHGSRAVGG----LLVPPSDRPWRL
MAV_2450|M.avium_104                AAVLAVG---EPQTLLRNGTVYTARVLGSRAVGA----LLVPPEDGPWRL
MLBr_00135|M.leprae_Br4923          AVLADLG---ESQLLVRCNTVHAARLS--PAPQL----LALPVGESMWRL
MAB_3148c|M.abscessus_ATCC_199      GELVSGS--EEDETAWREDHWYRARLNLGPLGPDDWRSTVATPNNEGVRF
TH_4621|M.thermoresistible__bu      VQLLGGG--AEDETAWRDGQWYTARLSLSPLRPEERKQAVVDCERDGMRL
                                      :       * :   * .    .*:                       :

Mflv_0405|M.gilvum_PYR-GCK          APTERGAIDNLRLTDS-EVPPPAE-GYVQVRVEAAGLNFRDVLNVLGLYP
MSMEG_0408|M.smegmatis_MC2_155      APTERGAIDNLRLTET-DVPEPDE-GYVQVRVEAAGLNFRDVLNVLGLYP
Mvan_1003|M.vanbaalenii_PYR-1       APTERGVLDNLRVSET-EVTAPPE-GHVQVRVEAAGLNFRDVLNALGLYP
MMAR_3025|M.marinum_M               GMSTAGTFENLRLEPIPDADAALQPGHVRVALSAMAANFRDVMIALGLYP
MUL_2266|M.ulcerans_Agy99           GMSTAGTFENLRLEPIPDADAALQPGHVRVALSAMAANFRDVMIALGLYP
Mb2074c|M.bovis_AF2122/97           AMSTAGTFENLRLELIPDADAPLGPGQVRVAVSAIAANFRDVMIALGLYP
Rv2048c|M.tuberculosis_H37Rv        AMSTAGTFENLRLELIPDADAPLGPGQVRVAVSAIAANFRDVMIALGLYP
MAV_2450|M.avium_104                GMSSYGTIENLRLEPIPDADAPLGPGQVRVATSALAANFRDVMIALGLYP
MLBr_00135|M.leprae_Br4923          AADGGGTLEDLVIQPCPEVQAPLQAGHMRVAVAAVGVNFRDVVAALGMYP
MAB_3148c|M.abscessus_ATCC_199      EVRTPGDLQSLGFVAFDRVAPGPG--QIEVSVTATSINFADVLNVYGRYS
TH_4621|M.thermoresistible__bu      EIRTPGDLETMELAAFDRVPPGPG--QIEVAVTASSINFADVLIAFGRYP
                                         * :: : .     .        :.*   * . ** **: . * *.

Mflv_0405|M.gilvum_PYR-GCK          ---GDPGPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQGAFA-SRFNVPG
MSMEG_0408|M.smegmatis_MC2_155      ---GDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFA-SRFNVPA
Mvan_1003|M.vanbaalenii_PYR-1       ---GDPGPIGGELAGVVTAPGPDVDGFDVGQRVFGFAVGAFA-SRVNVPV
MMAR_3025|M.marinum_M               ---DPDAAMGVEGAGVVVETASTDGRFAVGDRVVGLFPEGTG-TIAITDH
MUL_2266|M.ulcerans_Agy99           ---DPDAAMGVEGAGVVVETASPDGRFAVGDRVVGLFPEGTG-TIAITDH
Mb2074c|M.bovis_AF2122/97           ---DPDAVMGVEACGVVIETSLNKGSFAVGDRVMGLFPEGTG-TVASTDQ
Rv2048c|M.tuberculosis_H37Rv        ---DPDAVMGVEACGVVIETSLNKGSFAVGDRVMGLFPEGTG-TVASTDQ
MAV_2450|M.avium_104                ---DPDAVMGIEASGVVIETASQDGRVAVGDRVMGLFPDGTG-TVATTDQ
MLBr_00135|M.leprae_Br4923          ---GQAPPLGAEGAGVVIEIGPEVTGVAVGDAVMG-FLGGAG-PLAVVHQ
MAB_3148c|M.abscessus_ATCC_199      SFEGRQ-ELGVDFAGVVTAVGEGVTQHQVGDRVGGMTPTGAWRSFVVVDA
TH_4621|M.thermoresistible__bu      TFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGCWSTFVTCDA
                                       .    :* : .*.*   .       :*: * *    .   .      

Mflv_0405|M.gilvum_PYR-GCK          QFLAPIPDGVSAVEAATIPAAALTVRLSF-DWAQVKSGDKVLIHAASGGV
MSMEG_0408|M.smegmatis_MC2_155      QFLAPIPDGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKVLIHAASGGV
Mvan_1003|M.vanbaalenii_PYR-1       QFLAPVPEGISAVAAATTPAAVLTAGLAF-DWAALRAGDRVLIHAASGGV
MMAR_3025|M.marinum_M               RLLVKIPAGWSDTAAATTSVVFATAFYALRDLASVQPGQRILVHAATGGV
MUL_2266|M.ulcerans_Agy99           RLLVKIPAGWSDTAAATTSVVFATAFYALRDLASVQPGQRILVHAATGGV
Mb2074c|M.bovis_AF2122/97           RLLVKVPAGWSHTAAATTSVVFATAHYALVDLADVQPGQRVLIHAGTGGV
Rv2048c|M.tuberculosis_H37Rv        RLLVKVPAGWSHTAAATTSVVFATAHYALVDLAAARSGQRVLIHAGTGGV
MAV_2450|M.avium_104                RLLVKVPAGWSHTAAATASVVFATAYYALVDLADARPGQRVLVHAAAGGV
MLBr_00135|M.leprae_Br4923          QLITQMPQGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLIHAGTGGV
MAB_3148c|M.abscessus_ATCC_199      NLAATLPAEVPDREAAAVPGAHVTAWYGLHELARISAGDKVLIHSGTGGV
TH_4621|M.thermoresistible__bu      DLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLIHSATGGV
                                     : . :*       **: . .  *.  .: : *   .*: :*:*:.:***

Mflv_0405|M.gilvum_PYR-GCK          GLAAVQMAQQCGAEVYATAST-FKRATLRKLG--VKHVYDSRTTDFAEQI
MSMEG_0408|M.smegmatis_MC2_155      GLAAIQMAQQSGAEVFATAST-FKRSTLRRLG--VKYVYDSRTTDFADQI
Mvan_1003|M.vanbaalenii_PYR-1       GLAAVQLARQRGATVFATASG-YKRPMLRAMG--VDHVYDSRTTDFADQI
MMAR_3025|M.marinum_M               GMAAVQLARHWGLEVFATASK-GKWDTLRAMGFDEDHIGDSRSLEFEDKF
MUL_2266|M.ulcerans_Agy99           GMAAVQLARHWGLEVFATASK-GKWDTLRAMGFDEDHIGDSRSLEFEDKF
Mb2074c|M.bovis_AF2122/97           GMAAVQLARHLGLEVFATASK-GKWDTLRAMGFDDDHISDSRSLEFEDKF
Rv2048c|M.tuberculosis_H37Rv        GMAAVQLARHLGLEVFATASK-GKWDTLRAMGFDDDHISDSRSLEFEDKF
MAV_2450|M.avium_104                GMAAVQLARHLGLEVFATASR-GKWDTLRDMGFDDDHLGDSRGLDFEDKF
MLBr_00135|M.leprae_Br4923          GMAAVQFARHWGVEIFVTASR-GKWDTLRDMGFDDDHIGDSRTLEFEEKF
MAB_3148c|M.abscessus_ATCC_199      GQAAIAIARAAGAEIYATAGSPERRDLLRSWG--IKHVYDSRSTDFAELI
TH_4621|M.thermoresistible__bu      GLAAIAIARSVGAQIYATAGSPARRDLLRDMG--IEHVYDSRSTAFADEI
                                    * **: :*:  *  ::.**.   :   **  *   .:: ***   * : :

Mflv_0405|M.gilvum_PYR-GCK          LADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDIW--TVEQ
MSMEG_0408|M.smegmatis_MC2_155      LADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDIW--SHEQ
Mvan_1003|M.vanbaalenii_PYR-1       LADTDGAGVDVVLNSLTNDGFVAATVRATARNGRFAEIAKRDIW--SPEQ
MMAR_3025|M.marinum_M               RAATGGRGMDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDIR--EAAV
MUL_2266|M.ulcerans_Agy99           RAATGGRGMDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDIR--EAAV
Mb2074c|M.bovis_AF2122/97           RAATGGRGFDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDIR--DPGV
Rv2048c|M.tuberculosis_H37Rv        RAATGGRGFDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDIR--DPGV
MAV_2450|M.avium_104                RAVTGGAGMDIVLDSLSGD-SVDASLRLVAPGGIFLEMGKTDIR--DPEV
MLBr_00135|M.leprae_Br4923          LAVTDGRGVDVVLDSLAGD-FVDASLRLLVRGGRFLEMGKTDIR--DAQE
MAB_3148c|M.abscessus_ATCC_199      RRDTDGYGVDIVLNSLTGA-AQRAGVELLTFGGRFIEIGKRDIYGDTRLG
TH_4621|M.thermoresistible__bu      RRDTDGYGVDVVLNSLPGA-AQRAGLELLSFGGRFIEIGKRDIYGDTRLG
                                       *.* *.*:**:**..     * :.     * * *:.* **       

Mflv_0405|M.gilvum_PYR-GCK          MAAARPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDGAWTPLPAEVY
MSMEG_0408|M.smegmatis_MC2_155      MAEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPLPAEIY
Mvan_1003|M.vanbaalenii_PYR-1       MAAARPDIDYEVLALDAVMQQDPDRIQLLLADLADSLARGETAPLPFEAY
MMAR_3025|M.marinum_M               VAQQHTGVRYRAFDLFEAG---PDHIAQILAELAALFSEDALRPLPVTTF
MUL_2266|M.ulcerans_Agy99           VAQQHTGVRYRAFDLFEAG---PDHIAQILAELAALFSEDVLRPLPVTTF
Mb2074c|M.bovis_AF2122/97           IAQQYPGVRYRAFDLFEAG---PDRIAQILAELATLFGDGVLRPLPVTTF
Rv2048c|M.tuberculosis_H37Rv        IAQQYPGVRYRAFDLFEPG---PDRIAQILAELATLFGDGVLRPLPVTTF
MAV_2450|M.avium_104                VAAEHPGVRYRAFDLFEAG---PDRIARLLDELAAMFGEDVLRPLPVTRF
MLBr_00135|M.leprae_Br4923          IAANYPGVQYRAFDLSEAG---PVRMQEMLCEVRELFDTQVLHRLPVTSW
MAB_3148c|M.abscessus_ATCC_199      LFPFRRNLSFHAVDLVLVAKTRPEAIYRTLTALYGQMAEGVLPLPEISPS
TH_4621|M.thermoresistible__bu      LFPFRRNLAFHGVDLGLMADSHPHKIRELLETVYRLTADGVLPMPQSTHY
                                    :     .: :. . *       *  :   *  :                 

Mflv_0405|M.gilvum_PYR-GCK          PLTEARAAFRRMQQARHIGKIVVQIPNP------------LQPQPDRSYL
MSMEG_0408|M.smegmatis_MC2_155      PITEARSAFRRMQQARHIGKIVLQVPKP------------LQPQQDRSYL
Mvan_1003|M.vanbaalenii_PYR-1       PLAEATTAFRRMQQARHTGKIILQMPKP------------LQPHGDRSYL
MMAR_3025|M.marinum_M               DVRRAPAALRYLSQARHVGKVVLTMP---------------DAWAAGTVL
MUL_2266|M.ulcerans_Agy99           DVRRAPAALRYLSQARHVGKVVLTMP---------------DAWAAGTVL
Mb2074c|M.bovis_AF2122/97           DVRRAPAALRYLSQARHTGKVVMLMP---------------GSWAAGTVL
Rv2048c|M.tuberculosis_H37Rv        DVRCAPAALRYLSQARHTGKVVMLMP---------------GSWAAGTVL
MAV_2450|M.avium_104                DVRRAPAALRYLSQARHVGKVVMTMP---------------DAWTAGTVL
MLBr_00135|M.leprae_Br4923          DVRCAPAAFRFMSQARHIGKVVLTMPSA-----------LADGLAEGTVL
MAB_3148c|M.abscessus_ATCC_199      PLQEAAESIRVMGAAGHTGKLVLDLPKAGEVSAVIPPSHAPAFRRDGAYV
TH_4621|M.thermoresistible__bu      PLAEAATAIRVMSAAEHVGKLVLDVPHTGRADVVVPPEQASPFRSDGAYI
                                     :  *  ::* :  * * **::: :*                     : :

Mflv_0405|M.gilvum_PYR-GCK          ITGGLGAIG-LHTAGYLAQLGAGDIVLTSRRAPDAAAQQAIADIADRTKA
MSMEG_0408|M.smegmatis_MC2_155      ITGGLGAIG-LHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKC
Mvan_1003|M.vanbaalenii_PYR-1       ITGGLGALG-LHAAAYLAQLGAGDIVLTGRRMPDAATERAISEIAERYHC
MMAR_3025|M.marinum_M               ITGGTGMAGSALARHVVAHHGVRQLVLVSRRGPDAPGAAELAEELSAFGA
MUL_2266|M.ulcerans_Agy99           ITGGTGMAGSALARHVVAHHGVRQLVLVSRRGPDAPGAAELAEELSAFGA
Mb2074c|M.bovis_AF2122/97           ITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGA
Rv2048c|M.tuberculosis_H37Rv        ITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGA
MAV_2450|M.avium_104                ITGATGMAGSAVARHVVTRHGARNLVLVSRRGLDAPDAAELVAELTAAGA
MLBr_00135|M.leprae_Br4923          ITGASGAIGGVLARHMVSAYGVRHLVLASRRGDRAEGAVELAAELVGAGA
MAB_3148c|M.abscessus_ATCC_199      VTGGLGGLG-LFLARKLAAAGVGRIILNGRSAPKPEALAAIEQIRQGGTE
TH_4621|M.thermoresistible__bu      VTGGMGGLG-LYLAGEMAAAGAGCIVLNGRSAPSGEALRTIEQLRAAGTE
                                    :**. *  *       ::  *.  ::* .*          :         

Mflv_0405|M.gilvum_PYR-GCK          RLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQQSVE
MSMEG_0408|M.smegmatis_MC2_155      RIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPE
Mvan_1003|M.vanbaalenii_PYR-1       RIHTFAADVGDESAVRDLLERIRTELPPLAGVAHLAGVLDDALLPQQSPE
MMAR_3025|M.marinum_M               QVQVVACDAADRAALAKLIADIPVQHP-LSAVIHTAGALDDAVVTSLTPE
MUL_2266|M.ulcerans_Agy99           QVQVVACDAADRAALAKLIADIPMQHP-LSAVIHTAGALDDAVVTSLTPE
Mb2074c|M.bovis_AF2122/97           QVQVVACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPD
Rv2048c|M.tuberculosis_H37Rv        QVQVVACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPD
MAV_2450|M.avium_104                HAEVVACDAADREALAKVIADIPMQHP-LTGVIHAAGVLDDAVVTSLTPQ
MLBr_00135|M.leprae_Br4923          KIQVVACDVADNDAVRGLFAQLSREFPPVRGVIHAAGVLDDGAITSLTPD
MAB_3148c|M.abscessus_ATCC_199      IDVALGDIAEPDTAQRLVAAATETGKPVRGVLHAAALVHDATLANITDEL
TH_4621|M.thermoresistible__bu      VIVECGXX----XRGQPVEVAVPT------ELRHADEHPDRRGAQLCDEF
                                                     :             :       *          

Mflv_0405|M.gilvum_PYR-GCK          RFRTALAPKAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSPGQSNYATAN
MSMEG_0408|M.smegmatis_MC2_155      RFRTTLAPKAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANYATAN
Mvan_1003|M.vanbaalenii_PYR-1       RFRTTLAPKAFGAWHLHRLTRDTELEFFIVYSSGSSVLGSPGQANYATAN
MMAR_3025|M.marinum_M               RMETVLRAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQGNYAAAN
MUL_2266|M.ulcerans_Agy99           RIETVLRAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQGNYAAAN
Mb2074c|M.bovis_AF2122/97           RVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAAAN
Rv2048c|M.tuberculosis_H37Rv        RVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAAAN
MAV_2450|M.avium_104                RIDTVLRAKVDAAWNLHELTRDLDVGAFVMFSSIAGLAGASGQGNYAAGN
MLBr_00135|M.leprae_Br4923          RVDTVLRAKVDAAWNLHEATRDLDLLMFVLCSSIAATVGSPGQGNYSAAN
MAB_3148c|M.abscessus_ATCC_199      IDRGDWRPKVHGAWNLHEATADQPLDWFCSFSSIAALVGSPGQGAYAAAN
TH_4621|M.thermoresistible__bu      A-----RGEQGAQRNQHRTDAGEGQRDAHPPGAVGHDQPDPG----ALSD
                                            :  .  : ..             .: .     .*    : .:

Mflv_0405|M.gilvum_PYR-GCK          AFLDGLVAQRRAQGLPATGVNFGPWARGGMASSEAAAANIS---AQGLIP
MSMEG_0408|M.smegmatis_MC2_155      AMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANIT---AQGLIP
Mvan_1003|M.vanbaalenii_PYR-1       AVLDGLVAHRKARGLPATGVNWGPWAQGGMATSDAARANLG---AQGLIP
MMAR_3025|M.marinum_M               SFLDGLAVHRQAHGLPAISLGWGLWDQASNMTGGLAAVDFKRFARDGIVA
MUL_2266|M.ulcerans_Agy99           SFLDGLAVHRQAHGLPAISLGWGLWDQASNMTGGLAAVDFKRFARDGIVA
Mb2074c|M.bovis_AF2122/97           SFLDALAAHRRAHGLPAISLGWGLWDQASAMTSGLATVDFKRFARDGIVA
Rv2048c|M.tuberculosis_H37Rv        SFLDALAAHRRAHGLPAISLGWGLWDQASAMTGGLATVDFKRFARDGIVA
MAV_2450|M.avium_104                SFLDGLAAHRRAHGLPAISLGWGLWDQASAMTGGLGAADLARFGRDGIVA
MLBr_00135|M.leprae_Br4923          AFLDGLAAYRQAAGLAGTSLAWGLWEQPGGMNAHLSSRDLARISRSGLAP
MAB_3148c|M.abscessus_ATCC_199      SWLDGFTHWRRAQGLPATVIAWGAWSEIGQGTHLAQNAEAA---------
TH_4621|M.thermoresistible__bu      TGLD----ERGGQFPGVGVQIPVADPGVGIDHRGAVRVDSG---------
                                    : **     * .                .         :           

Mflv_0405|M.gilvum_PYR-GCK          LEPSAALTAMAEVVANGTAQATVLKANWQR-AAKVLGSSRPPILDLVLPS
MSMEG_0408|M.smegmatis_MC2_155      LDPSAALHALAEVIANGSGQATVLKANWQR-AAKVLGSARPPILDLVLPS
Mvan_1003|M.vanbaalenii_PYR-1       LEPTAALNALGEIVAHGIASAVVLKANWQR-AAKLLGATRPPILDHVLPS
MMAR_3025|M.marinum_M               MSSDEALGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMFVDLINA
MUL_2266|M.ulcerans_Agy99           MSSDEALGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMFVDLINA
Mb2074c|M.bovis_AF2122/97           MSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMFVDLINA
Rv2048c|M.tuberculosis_H37Rv        MSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMFVDLINA
MAV_2450|M.avium_104                MSSQEALELMDTALIVDEPFLLPAHIDLAALRVKFDGGTLPPMFVDLINA
MLBr_00135|M.leprae_Br4923          MNPAQALELFDAALVIDHPFMVTALLDRAALDAQAQAGALPPLFSRLVRR
MAB_3148c|M.abscessus_ATCC_199      ILPDEGAYAFDTVLRHNRAYTAYAPMAGISWLADFVERSPFAQAFRDAGQ
TH_4621|M.thermoresistible__bu      VPAQQGVDG--EVVRH-RTLSSVRSGRSSRWTAP---GSRCGSGRRYGGE
                                    : .  .       :                  .     :           

Mflv_0405|M.gilvum_PYR-GCK          AVGEITGDS--------ELLKQLQEIPVPQRAGFVTEFLQKEVQNFLRLA
MSMEG_0408|M.smegmatis_MC2_155      AAGEATGDS--------ELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLA
Mvan_1003|M.vanbaalenii_PYR-1       AVAAGPGDS--------ALLKQLQDVPEAQRGSFVTEHLQRELQQILGLA
MMAR_3025|M.marinum_M               PTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIATVLGNS
MUL_2266|M.ulcerans_Agy99           PTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIATVLGNS
Mb2074c|M.bovis_AF2122/97           PTRRQVDDSLAAAKSKSALAHRLHGLPEDEQHAVLLDLVRSHIATVLGSA
Rv2048c|M.tuberculosis_H37Rv        PTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAVLLDLVRSHIATVLGSA
MAV_2450|M.avium_104                PTRRQVDDSLAAAKSKSALLQRLEGLPEDEQQAVLLDLVRSNIATVLGSS
MLBr_00135|M.leprae_Br4923          SRRRQIEDPGDATQSKLALVQRLQGLAANRQLELLVGVVCLQAAAVLGRP
MAB_3148c|M.abscessus_ATCC_199      NQTET---------------NKFLDELRALPREEWPTRLRKLVAEQVGLV
TH_4621|M.thermoresistible__bu      S-------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QPPAATS--RFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIG
MSMEG_0408|M.smegmatis_MC2_155      SPPAASS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIG
Mvan_1003|M.vanbaalenii_PYR-1       QPPAATG--RFLELGMDSLMAVELRNRLVGQFGSGFTITATAVFDYPTIG
MMAR_3025|M.marinum_M               SPDAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPNSA
MUL_2266|M.ulcerans_Agy99           SPDAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPNSA
Mb2074c|M.bovis_AF2122/97           SPEAIDPDRAFQDLGFDSLTAVEMRNRLKSATG--LSLSPTLIFDYPNSA
Rv2048c|M.tuberculosis_H37Rv        SPEAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPNSA
MAV_2450|M.avium_104                SPEAIHPDRAFQELGFDSLTAVEMRNRLKAATG--LALSPTLIFDYPNSA
MLBr_00135|M.leprae_Br4923          SPEDIDPNTKFQDLGFDSLTAVELRNRLKSATG--LTLPPTVIFDHPTPT
MAB_3148c|M.abscessus_ATCC_199      LRRSIDPDRSLPDYGLDSLGNLEIRTRIQADTGVRIGPADVSTVRSLAAH
TH_4621|M.thermoresistible__bu      CRRTTGP----------AAGAAARRGRTRRRRRPRRPPPPPDRVRHRAGP
                                                     :      * *                .      

Mflv_0405|M.gilvum_PYR-GCK          GLAEYLVAQLPDAETP----------------------------------
MSMEG_0408|M.smegmatis_MC2_155      GLAEYLVGQLPDAEAP----------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       ALAEYLAAQTPESTEE----------------------------------
MMAR_3025|M.marinum_M               ALAGYMHRELVGASPQSDITAEAPGEAELQRVVASIPVKRLRQAGVLELL
MUL_2266|M.ulcerans_Agy99           ALAGYMHRELVGASPQSDTTAEAPGEAELQRVVASIPVKRLRQAGVLELL
Mb2074c|M.bovis_AF2122/97           ALAGYMRRELLGSSPQ-DTSAVAAGEAELQRIVASIPVKRLRQAGVLDLL
Rv2048c|M.tuberculosis_H37Rv        ALAGYMRRELLGSSPQ-DTSAVAAGEAELQRIVASIPVKRLRQAGVLDLL
MAV_2450|M.avium_104                ALAGYMYRELVGTSEQ-PTAAAAPGEAEIQRVVGSIPVKRLRQAGVLELL
MLBr_00135|M.leprae_Br4923          AVAEYVAQQMLKSRPA----------------------------------
MAB_3148c|M.abscessus_ATCC_199      IYDRLAEQESEVASS-----------------------------------
TH_4621|M.thermoresistible__bu      AHGPVRR-------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -----QAAPQSESEPGPDVTE----------------------
MSMEG_0408|M.smegmatis_MC2_155      -----ETA-----------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       -----GTEMKTADPDGQPATVGHADVVLQTS------------
MMAR_3025|M.marinum_M               LALANETGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE-
MUL_2266|M.ulcerans_Agy99           LALANETGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE-
Mb2074c|M.bovis_AF2122/97           LALANETETSGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE-
Rv2048c|M.tuberculosis_H37Rv        LALANETETSGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE-
MAV_2450|M.avium_104                LALANESTGTAQSATPAVTTEKDIADMDLDDLVNAALLDDDDE
MLBr_00135|M.leprae_Br4923          -----ESGDETSQAVEPKVEEVSVHA-----------------
MAB_3148c|M.abscessus_ATCC_199      -------------------------------------------
TH_4621|M.thermoresistible__bu      -------------------------------------------