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M. marinum M MMAR_3798 (-)

annotation: type I modular polyketide synthase
coordinates: 4696935 - 4713422
length: 5495

MENEERLRKYLQKAANDLRKSNKRVRELERRTVEPVAVVGMACRFPGGADSPDGLWQMVSEGRDVLSEFP
SDRGWDLGGLYDPEPDRVGYVHARAGGFLDGVADFDAGFFGISPREALGMDPQQRLILEIAWETLESASI
DPQSLRGSQTGVFAGTMTSCYGVGIDNVTSAVSGRVAYAFGFEGPAVTVDTACSSSLVAIHQACQSLRGG
ECSMALAGGVTVMATPDVFAEFARQRGLSADGRCKAFAASADGTGFGEGAGLVLLERLSDARRNRHPVLA
VIRGSAVNQDGASNGLTAPNGPAQERVIRSAVAAAGLRVADVDVVEAHGTGTTLGDPIEAHALLATYGAD
RDAEQPLWLGSVKSNMGHTQAAAGVAGLIKMIQAINHAVLPPTLHVDAPSPHIDWSAGAVRLLTEAVPWP
DTGRARTAGISSFGISGTNAHLIAQEAPQESTADPSPSDVCEPLFRVWPVSGRTAEALNAQAERLGQYLV
DHPDLDLTDLAYSLATTRAHHAYRAAVTVPGDTVNTRDDLLAGLRSLAVDQFHPGVTYHHYRLGQAGKTV
FVFPGQGAQYAGMGAGLYRHHPVFTTAIDEICAVMDEHLDVPLRDVMFTEPGLLQQTVYAQPALFAFGVA
MHAVLTQAGVNPDYLLGHSVGELTAAHVAGVLSLEEAAVLVCARGRLMQSCTPGAMMAISASEPAVAAML
ENHPEVVIAAVNGPTSVAVAGPAEQLNALREHCNISNHKVTLLRVSHAFHSPAMDPILAEFEAIAKRLTY
RPHSVPIMSNLTGSLATVEQLTSARYWAQHLRKPVRFYDGVTRLLAGGEQAFVELSPHPVLAAAITDTLT
GVTDRVGSAVVTTLRRDRPDMDMVASAIANLHVHGHSPSWQKIYPGATTVELPTYPFQHRRYWLDPAPRA
DVSAAGLDQPEHPLLAAVTELADQDQIVLSGRLSTSAHRWLAGHQLGDTVVLPATALIDMALYAGEHTGC
PTIDELVLQTPLTLTPDAATDLQISVAAPDEQNRRTFSVHARTSEHPHQHSTWVLHASGTLSNAPSTTPP
TKPLPGPQAITKVNQESFYDQLAQHGLHYSEAFRSIQGIGKDPLNPDAICAEVALPADIETHGYGIHPAL
LDAALHPLTAALADTNTNSGPQLPFAIAGITLHATGASRMHVQLEPTATDTFRLSATDPVGAPVITIDSL
TVRSLPDTDLTQPPTHKAQQGIFELTWPALPAETFPATGVLPPWALISPHPENLSPDLNQSPTYPNLTAL
PTCPPLVIWDLTTPQPPQSDLLHQVHTLTQHTLAGLQNWLNRSDTLQAHLVVLTRHAVTTSPHDLAPDPA
QAATAALIHTTQNEHPNRITLIDIDNTPTTSQTLTNILTTLTNPTSAPTEPQLALRHGTPHTPRLTPTQV
LTPPAAPNWELATTGKGDLANLALLPTPPHTELGPGQIRVAVRAAGLNFRDVVVALGAIGEEGLGGEAAG
IIIDTGPDVTAFRRGDAVMGLFPNNAFAATAVTDHRMVVPIPAGWSFAAAASIPVAFLTAYGAMVELGAL
AAGRRVLIHAGAGGVGQAAIQIARHFGAEVYATAHPSKHHVLKALGVSGDRIASSRTFDFVDVFNQGTNG
EGMDLVLNSLAGDFVDNSLRLLSQGGRLIEIGKTDIRVPNEVAAAHPGVIYRTYDLSSETPDRISQLWAA
LIEMISAGVLRPLPTTSYGLLQATQALRHMSQGRHTGKIVLLPPGVFNSEGTVLVTGGTGMLGGVFAERL
VAHYGARHLLLVSRSGPDAAGADELYQRLTQLGAQVTITACDTSNPDELAAVLAGIPPQHPLRAVVHTAG
IVDDAVTTELTHEQLDTVLTAKADTAWHLHQLTTDADLDAFVVFSSVAGVLGAPGQANYAAANAFLDALA
HQRHRNHLPATSLAWGYWQTTSGMTAHLDTVDQARLTRNSLTPITTEHGLAMFDVALACQHPCLVPAPLN
TQVLAGYARQNALPAILSAVTTTRRQATTTNTETFTSRLASQTPQQQLAILSDLVTDMTAAVLAHPDSAA
LDADLPFKDLGIDSLSALELRNSLARHTGLTLSATLVFDHPTPTAIAHHLVDQLSAAAPPAPVATPVKAN
AEEPVVVVGMACRLPGGIESAAGLWDVVSGAADVMGAFPTDRGWDVAGLFDPDPDSVGKTYTRYGGFISS
AAEFDAEFFGISAREAAAMDPQQRVLLEVCWEALEHAGIEPGTLEGSNTGVFIGAYAQRYGDSDSDSGEG
FALTGGATSVASGRVAYVLGLQGPAITVDTACSSSLVAAHLACQSLRNGESSLALAGGVTIMATPAPFIE
FARQRGLAADGRCKAFAAAADGTGWGEGAAVLVLERLSDARRNRHPVLAVIAGSAVNQDGASNGLSAPNG
PAQQRVIAQAAANAGIALDQVDVVEAHGTGTTLGDPIEAGALIATYGTHRDPEHPLWLGSVKSNIGHTQA
AAGAAGLIKMIQAMRHGVLPKTLHVNAPTPQVDWSAGTVRLLTETMPWPDTDHLRTAAVSSFGVSGTNAH
LIVQQGSPGPAVAVHQASPSQECSLGVWPLSARSSAGLSAQAHRLHEYLLGHSDLDLIDLAYSLATTRTH
HSYRAAVTVPGCTDNAHHDLLGGLTALAAGQTHPFVANHYCRAGQNGKTVFVFPGQGGQYPAMAAELYRQ
HPGFATAVDECDAELRPYTGWSVRDVICQDPDAPSLELVEVIQPVLFAVMIALAETLRGYGIVPDAVIGH
SQGEIAAAYIAGALTLAEAAKVVALRSAALAQLAGTGTMASVLLSPEELRPLLQPWNTQISIAAINGPAH
TIISGDTTAVEQFIGTCEDGGVQIRPIAVDYASHSAHVERLREHLLHELADLNPQPARIPLYSTVASELS
EHPLDTTAMDAEYWYRNLREPVEFYSCVAQLLAHSERVFVELSPHPVLASALTDALADTGQLTQSAVVTT
LRRDRPDMDMVASAIANLHVHGHSPSWQKIYPGATTVELPTYAFQRRHYWLAAPTPTPATVSDPAEVALW
DAVNDDAVDTVARVLRIDNAQSMVSLGPMVRALREWRKELGDRSVVGQLRYQVGWRNVTPNTFPQTRQRW
LVLTLPEQSDDVWVAGFSARFADSVAMLAIDPHMFDRNSLAALLADEATRNKCDGVVSFMALRERTHQDF
RGISTALLSTLHITQAYGDSGLDLPLWVITQGGAQVNPDEDLTPSQSAVWGLGQSACLEHPTWWGGLVDL
PVSPAPQDFNRLQAILTCQQSEDQLAIRAAGVSARRLHKASLPQDRMRTWKISGTALVTGVTGHLGQHIA
RWLAQAGASHLVLLSRTAAEHPQVAELEKELNSAGITTTSISVDVTDRDALAAVVAETRIEHGPIHTVVH
AAAHIGLVTTAETTIDEFIKSFAAKALGAENLIAVLEDQPPQTFIMFSSAAATWGGTRQGAYAAANAYIE
ALVTRLRGRGCRAIAPAWGAWTDDRTTTQEVVGYFSRIGLNQISPDIAFAALQQSLDVDDTLITIADVDW
SQFRDVFTTTGRAHALLAELGTSQPQTAEIPAIAENSHFAAQLAKQAPQQQLATLIGLVTNVTAAVLAHP
DPAVLDPDLSFKDLGIDSLSALELRNTLTRDTGLTLPATVVFDHPTPTAVAEHLLGLLSGVTGPTLAVVP
TRVGVDVPVAVVGMACRLPGGIESAAGLWDVVSNGIDVMSGFPLDRGWDVAGLFDPDPDAEGKTYTRYGG
FVADVAGFDAEFFGISAREAITMDPQQRVLLEVCWQALEHAGIDPTTLEGSDTGVFVGIGAQSYVSGHSG
VEGYALTGASASVASGRVAYVLGLQGPAITVDTACSSSLVATHLACQSLRNGESSLALAGGATIMATPTP
FIEFARQRGLAADGRCKAFAAAADGTGWGEGAAVLVLERLSDARRNRHPVLAVIAGSAVNQDGASNGLSA
PNGPAQQRVISQALANAGLPFTHVDVVEAHGTGTTLGDPIEAGALIATYGTHRDPEHPLWLGSVKSNIGH
TQHAAGAAGLIKMIQALNHAVLPATLHIDQPSPHIDWSTDTVRLLTEATPWPETEHLRTGAVSAFGVSGT
NAHLIVQQAPPEVFESVPEPETARPSGQPLLRIWPVSAHTPAALTAQAERLSEYLTRHEDLSLTDLAYSL
ACTRTHHPYRAAVTVPVDTSNPGHDLAAALRALAANQPHPYVTCHHYRARQPSKTVFVFPGQGGQYPAMA
AELYRQHPGFATAVDECDAELRPYTGWSVRDVICQDPDAPSLELVEVIQPVLFAVMIALAETLRGYGIVP
DAVIGHSQGEIAAAYIAGALTLAEAAKVVALRSAALAQLAGTGTMASVLLSPEELRPLLQPWNTQISIAA
INGPAHTIISGDTTAVEQFIGTCEDGGVQIRPIAVDYASHSAHVERLREHLLHELADLNPQPARIPLYST
VASELSEHPLDTTAMDAEYWYRNLREPVEFYSCVAQLLAHSERVFVELSPHPVLASALTDALADTGQLTQ
SAVVTTLRRDRPDMDMVASAIANLHVHGHSPSWQKIYPGATTVELPTYPFQHRRYWLDPAPRADVSAAGL
DQPEHPLLAAVTELADQDQIVLSGRLSTSAHRWLAGHQLGDTVVLPATALIDMALYAGEHTGCPTIDELV
LQTPLTLTPDAATDLQISVAAPDEQNRRTFSVHARTSEHPHQHSTWVLHASGTLSNHPSRMFSPTTPFAA
GRTPNAVDQDSFYEELAQHGVRYDGAFRALHSLENNPSDTDTTCAEVALPADTDVDGYGIHPALLDAALQ
PLAAAFTDTDTDAPSAATPRMPFVITGVNLHATGARRLLVQLTATDADTFSLHATDPAGATVITINAVTL
RALTDIGSLRTSGISRRGLLELAWPALPPDTFSTAAVLPPLALVSSHSDDLAHALGQSSQCTVYTDLAAV
QPCPPLVLWDLTAGPDPTPTPEDGDTEDPLQRVHTLTRHTLAGLQNWLNRSDTTGTHLVILTRRAVTTVP
DDRSPDPAHAATWAFAHSAQNEHPNRITLIDIDNTPATSQTLTNILTTLTNPTSAPTEPQLALRHGTPHT
PRLTPTTTETTTTSPPLEFDPAGTVLITGGTGMLGAVFAEHMIARYGARHLLLVSRSGPDAPGADDLYQR
LTQLGAQITITACDASDPTALAAVLANIPTEHPLRAVIHTAAVIDDAVVTELTVEQLDMVLAAKADTAWH
LHRLTADINLDVFVVFSAAAAVLGAPGLANYAAANAFLDALAHHRHHHGLPATSLAWGYWQTPGIAAHLD
TVSQARFTRNHLIPITTEHGLALFDAALACQQPNLVPAPLNTHTLARQARQGVLPAILSSLITTRRHATI
GSVETLTAQLATQTPEQQLATLTRLVTTATAAVLAHPDPATLEPDLPFKDLGIDSLSALELRNTLTRDTG
ASLPATLVFDHPTPSAIAQYLNIQLSGSSTTSRVQDPEEIEMQNLIAKIPAKQLIKSGVLNILREIADIE
HSSSANEKQDNVATMNLDELLIALGDHKGENKNDH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_3798--100% (5495)type I modular polyketide synthase
M. marinum MMMAR_3799-0.092.89% (1392) type I modular polyketide synthase
M. marinum MMMAR_3025pks120.045.23% (3111) polyketide synthase, Pks12

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2074cpks120.045.68% (3087) polyketide synthase pks12
M. gilvum PYR-GCKMflv_0405-0.034.97% (3048) beta-ketoacyl synthase
M. tuberculosis H37RvRv2048cpks120.045.51% (3087) polyketide synthase pks12
M. leprae Br4923MLBr_00135-0.045.54% (2130) putative polyketide synthase
M. abscessus ATCC 19977MAB_0939-0.034.08% (3072) polyketide synthase
M. avium 104MAV_2450-0.045.79% (3097) erythronolide synthase, modules 3 and 4
M. smegmatis MC2 155MSMEG_0408-0.034.08% (3055) type I modular polyketide synthase
M. thermoresistible (build 8)TH_2454-0.032.93% (1831) PUTATIVE beta-ketoacyl synthase
M. ulcerans Agy99MUL_2266pks120.045.49% (3073) polyketide synthase, Pks12
M. vanbaalenii PYR-1Mvan_1003-0.035.00% (3037) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2074c|M.bovis_AF2122/97           -MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG
Rv2048c|M.tuberculosis_H37Rv        -MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG
MUL_2266|M.ulcerans_Agy99           -MVDQLQHATEALRKALVQVERLKRTKRALLERSSEPIAIVGMSCRFPGG
MAV_2450|M.avium_104                MMVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               --MENEERLRKYLQKAANDLRKSNKRVRELERRTVEPVAVVGMACRFPGG
Mflv_0405|M.gilvum_PYR-GCK          -----------------------MGSAAHQGE-SAHRFAIVGYAGRFPG-
MAB_0939|M.abscessus_ATCC_1997      -----------------------MDSAENPIE-STPRFAIIGYAARFPG-
MSMEG_0408|M.smegmatis_MC2_155      -----------------------MVSAEHPIE-PTPSFAIIGYAARFPG-
Mvan_1003|M.vanbaalenii_PYR-1       ---------MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPG-
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           VDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGF
Rv2048c|M.tuberculosis_H37Rv        VDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGF
MUL_2266|M.ulcerans_Agy99           VDSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHKSYASTGGF
MAV_2450|M.avium_104                VDSPEALWQMVAEGRDVISEFPTDRGWDLAALYDPDPDARHKCYVNTGGF
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ADSPDGLWQMVSEGRDVLSEFPSDRGWDLGGLYDPEPDRVGYVHARAGGF
Mflv_0405|M.gilvum_PYR-GCK          ARDAESFWELLADGRDAISEVPEDR-WDVEAFFDPDPSTPGKVVTRRAGF
MAB_0939|M.abscessus_ATCC_1997      AADAEEFWDVLREGRDAISEVPADR-WDAEEFFDPEPGAPGKVVTRRAGF
MSMEG_0408|M.smegmatis_MC2_155      AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAGF
Mvan_1003|M.vanbaalenii_PYR-1       AADADEFWDVLRGGRDAISEVPQDR-WDADEFFDADPEAAGKMVTRRAGF
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           VDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGS
Rv2048c|M.tuberculosis_H37Rv        VDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGS
MUL_2266|M.ulcerans_Agy99           VDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGS
MAV_2450|M.avium_104                VDNVADFDPAFFGIAPSEALAMDPQHRMLLELSWEALERAGIDPSGLRGS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               LDGVADFDAGFFGISPREALGMDPQQRLILEIAWETLESASIDPQSLRGS
Mflv_0405|M.gilvum_PYR-GCK          VDDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANT
MAB_0939|M.abscessus_ATCC_1997      VEDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTDLAET
MSMEG_0408|M.smegmatis_MC2_155      VDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANS
Mvan_1003|M.vanbaalenii_PYR-1       VEDVAGFDAPFFGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGT
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ATGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLE
Rv2048c|M.tuberculosis_H37Rv        ATGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLE
MUL_2266|M.ulcerans_Agy99           ATGVFAGLIVQGYG------MFAEEIEGYRLTGMTSSVASGRVAYVLGLE
MAV_2450|M.avium_104                ATGVFAGLIVQGYG------MLAEEIEGYRLTGMTSSVASGRVSYVLGLE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               QTGVFAGTMTSCYG------VGIDNVT---------SAVSGRVAYAFGFE
Mflv_0405|M.gilvum_PYR-GCK          NTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQ
MAB_0939|M.abscessus_ATCC_1997      NSGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQ
MSMEG_0408|M.smegmatis_MC2_155      NTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQ
Mvan_1003|M.vanbaalenii_PYR-1       RTGVFMGLSTHDYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQ
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           GPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFS
Rv2048c|M.tuberculosis_H37Rv        GPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFS
MUL_2266|M.ulcerans_Agy99           GPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFS
MAV_2450|M.avium_104                GPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GPAVTVDTACSSSLVAIHQACQSLRGGECSMALAGGVTVMATPDVFAEFA
Mflv_0405|M.gilvum_PYR-GCK          GPAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVILTPATMITFS
MAB_0939|M.abscessus_ATCC_1997      GPSVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFS
MSMEG_0408|M.smegmatis_MC2_155      GPAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFS
Mvan_1003|M.vanbaalenii_PYR-1       GPAVAVDTACSSSLVAVHQACQALRLAECDVALAGGVNVLLSPATMINFS
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           RHRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVV
Rv2048c|M.tuberculosis_H37Rv        RHRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVV
MUL_2266|M.ulcerans_Agy99           RHRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDAQRLGHPVLALVR
MAV_2450|M.avium_104                RHRGLAPDGRCKAYAGAADGVGWSEGGAMLVVERLSDARRLGHPVLAVVR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               RQRGLSADGRCKAFAASADGTGFGEGAGLVLLERLSDARRNRHPVLAVIR
Mflv_0405|M.gilvum_PYR-GCK          NAHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIR
MAB_0939|M.abscessus_ATCC_1997      HAHMLAPDGKCKTFDAAADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIR
MSMEG_0408|M.smegmatis_MC2_155      NAHMLAPDGRCKTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIR
Mvan_1003|M.vanbaalenii_PYR-1       RARMLAPDGRCKTFDATADGYVRGEGCGVVVVKRLADAIRHGDRIRAVIR
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
Rv2048c|M.tuberculosis_H37Rv        GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
MUL_2266|M.ulcerans_Agy99           GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
MAV_2450|M.avium_104                GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GSAVNQDGASNGLTAPNGPAQERVIRSAVAAAGLRVADVDVVEAHGTGTT
Mflv_0405|M.gilvum_PYR-GCK          GSAINQDGASGGLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTS
MAB_0939|M.abscessus_ATCC_1997      GSAINQDGASGGLTVPNGVAQQRVIADALKRAGVAPSEVGYLEAHGTGTS
MSMEG_0408|M.smegmatis_MC2_155      GSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVGYLEAHGTGTS
Mvan_1003|M.vanbaalenii_PYR-1       GSAVNQDGASGGLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTP
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           LGDPIEAQALLATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVI
Rv2048c|M.tuberculosis_H37Rv        LGDPIEAQALLATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVI
MUL_2266|M.ulcerans_Agy99           LGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVI
MAV_2450|M.avium_104                LGDPIEAQALLATYGQDRGQP------LWLGSIKSNMGHTQAAAGVAGVI
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               LGDPIEAHALLATYGADRDAEQP----LWLGSVKSNMGHTQAAAGVAGLI
Mflv_0405|M.gilvum_PYR-GCK          LGDPIEAQAAGAALGPGREPQRP----LLIGSAKTNIGHLEAAAGIAGVI
MAB_0939|M.abscessus_ATCC_1997      LGDPIEAQAAGAAYGIGRETNDP----LLIGSAKTNIGHLEAAAGIAGVI
MSMEG_0408|M.smegmatis_MC2_155      LGDPIEAQAAGEVLGAGRAPEEP----LLIGSAKTNIGHLEAAAGIAGVI
Mvan_1003|M.vanbaalenii_PYR-1       LGDPIEVQAAGAVLGVGREPDRP----LLIGSVKTNIGHLEAASGIAGLL
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           KMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTR
Rv2048c|M.tuberculosis_H37Rv        KMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTR
MUL_2266|M.ulcerans_Agy99           KMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVR
MAV_2450|M.avium_104                KMVLAMRHELLPATLHVDEPSPHVDWSAGAVSLLTEAQPWP----GERPR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               KMIQAINHAVLPPTLHVDAPSPHIDWSAGAVRLLTEAVPWP---DTGRAR
Mflv_0405|M.gilvum_PYR-GCK          KVVLSLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPR
MAB_0939|M.abscessus_ATCC_1997      KVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGR---NGRPR
MSMEG_0408|M.smegmatis_MC2_155      KVVMALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR---NGKPR
Mvan_1003|M.vanbaalenii_PYR-1       KVILSLEHQVLPKHLNFRSPSPHIPWNRLPVRIVDDPVPWTR---SGRSR
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           RAGVSSFGISGTNAHVIIEAVP---VVPRR-EAGWAGP-VVPWVVSAKSE
Rv2048c|M.tuberculosis_H37Rv        RAGVSSFGISGTNAHVIIEAVP---VVPRR-EAGWAGP-VVPWVVSAKSE
MUL_2266|M.ulcerans_Agy99           RAGVSSFGISGTNAHVIVEAAP---RVEVGGSSGGAVP-VVPWVVSAKSG
MAV_2450|M.avium_104                RAGVSSFGISGTNAHVIIEAVP---AVEPAHADAPALP-VLPWVVSAKSA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               TAGISSFGISGTNAHLIAQEAPQESTADPSPSDVCEPL-FRVWPVSGRTA
Mflv_0405|M.gilvum_PYR-GCK          IAGVSSFGFAGTNAHVILEEAPLAAEPAQES---VDDGRFTLLPLSARTP
MAB_0939|M.abscessus_ATCC_1997      IAGVSSFGFAGTNAHVILEEAPVVSRDAVEPPAPAGGRKFSILPLSARTP
MSMEG_0408|M.smegmatis_MC2_155      IAGVSSFGFAGTNAHVILEEAPAVGTPATTEP-VEDPRRYSVLPLSARTP
Mvan_1003|M.vanbaalenii_PYR-1       VAGISSFGFSGTNAHVLVEEAPRADRAGAAPQ-PAAPGGFGMLPLSARTP
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           SALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGG-----
Rv2048c|M.tuberculosis_H37Rv        SALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGG-----
MUL_2266|M.ulcerans_Agy99           SALGAQAARLAAHVRSHDELDVADVGWSLAG-RSTFEHRAVVLGA-----
MAV_2450|M.avium_104                AALRAQAARLAEYVRAQGELDIADVGWTLAG-RATFEHRAVVVGG-----
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               EALNAQAERLGQYLVDHPDLDLTDLAYSLATTRAHHAYRAAVTVPGDTVN
Mflv_0405|M.gilvum_PYR-GCK          AALMAVADRYRDWLVANPDATLADLCFTAGTARSHLEHRAALVVN-----
MAB_0939|M.abscessus_ATCC_1997      AALAQLADKYRAWLNAHPEAALADLCFTAGVGRAHLEHRAALVVN-----
MSMEG_0408|M.smegmatis_MC2_155      EALVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVN-----
Mvan_1003|M.vanbaalenii_PYR-1       DALAATAHRLRTWLAANPDASWPDLCFTAAVGRSHLRHRAALVVD-----
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           DRDRLLAGLDELAGDQLG-GSVVRGTAT-AAGKTVFVFPGQGSQWLGMGI
Rv2048c|M.tuberculosis_H37Rv        DRDRLLAGLDELAGDQLG-GSVVRGTAT-AAGKTVFVFPGQGSQWLGMGI
MUL_2266|M.ulcerans_Agy99           DRDGLLAGLDELAGDEFGGASVIRGVAG-AAGKTVFVFPGQGSQWIGMGI
MAV_2450|M.avium_104                DRDRLLAGLDELAADDPA-ASIIRGVAT-PAGKTVFVFPGQGSQWLGMAT
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               TRDDLLAGLRSLAVDQFHPGVTYHHYRLGQAGKTVFVFPGQGAQYAGMGA
Mflv_0405|M.gilvum_PYR-GCK          TREAALDLLGALADDRPAPGLVRGESHD--TPKTAWLFTGQGSQYPGMSR
MAB_0939|M.abscessus_ATCC_1997      TREAAVELLSAVADDRPAPGLGRGESHD--TPKTAWLFTGQGSQYPGMAR
MSMEG_0408|M.smegmatis_MC2_155      SRESAIELLGALADDRPAPGLVRGESHE--APKTAWLFTGQGSQYPGMAR
Mvan_1003|M.vanbaalenii_PYR-1       SRSSVEELLGALAEDRPGPGLARGECGD--PPKTAWLFTGQGSQYPGMGR
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGA------PGLDRV
Rv2048c|M.tuberculosis_H37Rv        ELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRGAPGA------PGLDRV
MUL_2266|M.ulcerans_Agy99           ELLDTAPVFARHIESCGQAFAEFVDWSLLDVLRGAAGA------PGLDRI
MAV_2450|M.avium_104                ELLDTAPVFAQHIQACEEAFAEFVDWSLIDALRGAPGA------AGMDRV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GLYRHHPVFTTAIDEICAVMDEHLDVPLRDVMFTEPG--------LLQQT
Mflv_0405|M.gilvum_PYR-GCK          ELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGVLDTDSNETLRHT
MAB_0939|M.abscessus_ATCC_1997      ELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVD---GPEAEETLRQT
MSMEG_0408|M.smegmatis_MC2_155      ELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDAD-ELDGDTESPLRHT
Mvan_1003|M.vanbaalenii_PYR-1       ELFDTEPVYREVMTRCAEAVADVLERPLLDVVFDAD------GGEALRHT
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           DVVQPVLFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDA
Rv2048c|M.tuberculosis_H37Rv        DVVQPVLFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDA
MUL_2266|M.ulcerans_Agy99           DVVQPVLFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDA
MAV_2450|M.avium_104                DVVQPALFAVMVSLAELWKSVGVSPDAVIGHSQGEIAAAYVAGALSLRDA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VYAQPALFAFGVAMHAVLTQAGVNPDYLLGHSVGELTAAHVAGVLSLEEA
Mflv_0405|M.gilvum_PYR-GCK          SYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLSLRDG
MAB_0939|M.abscessus_ATCC_1997      SYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLEDG
MSMEG_0408|M.smegmatis_MC2_155      TYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDG
Mvan_1003|M.vanbaalenii_PYR-1       SYAQPALYAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVMGLEDG
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ARVVTLRSKLLAGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPS
Rv2048c|M.tuberculosis_H37Rv        ARVVTLRSKLLAGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPS
MUL_2266|M.ulcerans_Agy99           AKVVTLRSKLLVGLAGPGGMVSVACGEQQARELLEPFGDRVSIAAINGPS
MAV_2450|M.avium_104                ARVVTLRSKLLRSLAGPGGMLSIACSTERARELLAPYGNRVSIAAVNGRS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               AVLVCARGRLMQSCT-PGAMMAISASEPAVAAMLENHP-EVVIAAVNGPT
Mflv_0405|M.gilvum_PYR-GCK          ARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEYPALSVAAYNG--A
MAB_0939|M.abscessus_ATCC_1997      ARLIAERGRLFSSLPAGGRMAAVFTDAERAERLTDEFPSLSVAAYNG--A
MSMEG_0408|M.smegmatis_MC2_155      ARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNG--A
Mvan_1003|M.vanbaalenii_PYR-1       AVLLAERGRLFGSLPEGGRMAAVFAPADRVESCTVDSPLLSVAAYNG--D
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AVVVSGEVGALEELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAEAL
Rv2048c|M.tuberculosis_H37Rv        AVVVSGEVGALEELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAEAL
MUL_2266|M.ulcerans_Agy99           AVVVSGEVAALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQLTEVL
MAV_2450|M.avium_104                AVVVSGEGAALDELAAFCADLALRTRRIDVDYASHSVEVEAIREDLAQAL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               SVAVAGPAEQLNALREHCNISNHKVTLLRVSHAFHSPAMDPILAEFEAIA
Mflv_0405|M.gilvum_PYR-GCK          NTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALLDPILDDFESYA
MAB_0939|M.abscessus_ATCC_1997      NTVLSGPAQDLEKAIAALVADGVRCDFLETSHAFHSALLDPILDEFEAYA
MSMEG_0408|M.smegmatis_MC2_155      NTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFA
Mvan_1003|M.vanbaalenii_PYR-1       NTVLSGPAGDLERAVAGFSAAGVRCDWLDTSHAFHSALLDPVLEEFESCA
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           SGIEPRSTRTVFFSTVTGNRLDTAGLD-ADYWYRNVRQTVLFDQAVRNAC
Rv2048c|M.tuberculosis_H37Rv        SGIEPRSTRTVFFSTVTGNRLDTAGLD-ADYWYRNVRQTVLFDQAVRNAC
MUL_2266|M.ulcerans_Agy99           AGIEPLSSRTAFFSSVTGSRLDTAELD-AEYWYRNIRQTVQFDQAVRSAC
MAV_2450|M.avium_104                TGIEPRSSRIAFFSTVTGNRLDTAGLD-ADYWYRNIRQTVQFDQTVRSAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               KRLTYRPHSVPIMSNLTGSLATVEQLTSARYWAQHLRKPVRFYDGVTRLL
Mflv_0405|M.gilvum_PYR-GCK          RGITFTAPQRILIDNRTGAALGRSVTLDAAYWRRHARQPVEFAKSVHTLA
MAB_0939|M.abscessus_ATCC_1997      NQFNYKTPQRILIDNRTGTALGRSVKLDGAYWRRHARQPVEFAKSVRTLA
MSMEG_0408|M.smegmatis_MC2_155      QKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLA
Mvan_1003|M.vanbaalenii_PYR-1       DRFEFGTPQRTLVCNRSGEVLSRHARLDGQYWRRHARQPVRFAESVRTLA
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           EQGYRTFIESSPHPALITGVEETFAACTDGD-SEAIVVPTLGRGDGGLHR
Rv2048c|M.tuberculosis_H37Rv        EQGYRTFIESSPHPALITGVEETFAACTDGD-SEAIVVPTLGRGDGGLHR
MUL_2266|M.ulcerans_Agy99           GHGYRTFIESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGREDGGLQR
MAV_2450|M.avium_104                EHGYRTFIESSPHPALVAGIEDTVNDSLPGD-TEAIVIPTLGRDDGGLER
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               AGGEQAFVELSPHPVLAAAITDTLTG--VTDRVGSAVVTTLRRDRPDMDM
Mflv_0405|M.gilvum_PYR-GCK          DMNCKLLVEIGPRPVLTAAALSAWPDPATSP----RVIASLRRTTADQRQ
MAB_0939|M.abscessus_ATCC_1997      DMNCKVLLEIGPQPVLTAAALRAWPDPATAP----RAIASLRRNTADHRQ
MSMEG_0408|M.smegmatis_MC2_155      DMNCRVLLEIGPRPVLTATALAAWPDPATTP----QVLASLRPTTADHRQ
Mvan_1003|M.vanbaalenii_PYR-1       DLGCRLLMEIGPQPVLTAAAMRTWPGTVTAP----RVAASMRRKGSDRRQ
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           FLLSAASAFVAGVAVNWRGTLDG-AGYVELPTYAFDKRRFWLSAEGSGAD
Rv2048c|M.tuberculosis_H37Rv        FLLSAASAFVAGVAVNWRGTLDG-AGYVELPTYAFDKRRFWLSAEGSGAD
MUL_2266|M.ulcerans_Agy99           FLASAAAAFVAGVNVDWRGPLDG-AGLVELPTYAFEKRRFWLSGEGVSVD
MAV_2450|M.avium_104                FLTSAATAFVAGVNVAWRGVLDG-AGFVELPTYAFDRRRFWLSGEGAAAD
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VASAIANLHVHGHSPSWQKIYPG-ATTVELPTYPFQHRRYWLDP-APRAD
Mflv_0405|M.gilvum_PYR-GCK          ITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDSRE---
MAB_0939|M.abscessus_ATCC_1997      ITEAAADAYVLGHLPDFGAFQHAPARKLDLPTYPFERRQYWFSDKRDGDN
MSMEG_0408|M.smegmatis_MC2_155      ITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDR
Mvan_1003|M.vanbaalenii_PYR-1       ITEALAQAYVAGHRPETAARQHGRGRLLDLPTYPFQHRAYWFP-------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           VSGLGLGASEHPLLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDVVL
Rv2048c|M.tuberculosis_H37Rv        VSGLGLGASEHPLLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDVVL
MUL_2266|M.ulcerans_Agy99           ASGLGLSAGGHALLGAVVELPESGGVVLTGRLALGAHGWLADHAVSGVVV
MAV_2450|M.avium_104                ASGLGLGTSEHPLLSAVVELPASGGVVLTGRLSPSLQGWLTDHAVSGTVV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VSAAGLDQPEHPLLAAVTELADQDQIVLSGRLSTSAHRWLAGHQLGDTVV
Mflv_0405|M.gilvum_PYR-GCK          PVAAAPQR---GARTETVRLLEDGRIEELAALLG----------------
MAB_0939|M.abscessus_ATCC_1997      RDAGNRQQNNGGPRTEAVRLLEDGKIEELANLLG----------------
MSMEG_0408|M.smegmatis_MC2_155      DTQTASAGSVTPHRTQAVRLLEDGQIEELAALID----------------
Mvan_1003|M.vanbaalenii_PYR-1       -QGQARTAPTDPVHTETVRFLDEERIDELAALLD----------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           FPGTGFVELAIRAGDEVGCSVLDELTLAAPLLLPAT----GSVAVQVVVD
Rv2048c|M.tuberculosis_H37Rv        FPGTGFVELAIRAGDEVGCSVLDELTLAAPLLLPAT----GSVAVQVVVD
MUL_2266|M.ulcerans_Agy99           FPGTGFVELAIRAVDEVGCSVVNELTLRTPLVLPAS----GSVAVQVVVG
MAV_2450|M.avium_104                FPGAGFVELAIRAGDEVGCSTVEELTLQAPLMLPAKDSGIGSVAVQVLVG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               LPATALIDMALYAGEHTGCPTIDELVLQTPLTLTPD----AATDLQISVA
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AGRDSNSRGVSIFSRADAQAG------WLLHAEGILRPGSVEPGADLSVW
Rv2048c|M.tuberculosis_H37Rv        AGRDSNSRGVSIFSRADAQAG------WLLHAEGILRPGSVEPGADLSVW
MUL_2266|M.ulcerans_Agy99           AAADSAERSVSIYSRTDTDTDTDAGSVWVCHAEGTLGADSAQPAADLSAW
MAV_2450|M.avium_104                EADESGRRDVSIFSRPDSDSP------WVCHAQGTLSTGSIEPGADLAAW
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               APDEQNRRTFSVHARTSEHPHQHS--TWVLHASGTLSNAPSTTPPTKPLP
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           PPAGAVTVDVADGYERLATRGYRYGPAFRGLTAMWAR---GEEIFAEVRL
Rv2048c|M.tuberculosis_H37Rv        PPAGAVTVDVADGYERLATRGYRYGPAFRGLTAMWAR---GEEIFAEVRL
MUL_2266|M.ulcerans_Agy99           PPAGAIAVDVADGYERLDARGYGYGPAFRGLTAMWAR---GEELFAEARL
MAV_2450|M.avium_104                PPAGATKVDIADGYQRLAARGYGYGPAFQGLTAAWVR---GDEVFAEVRL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GPQAITKVNQESFYDQLAQHGLHYSEAFRSIQGIGKDPLNPDAICAEVAL
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           PEAAGGVGGFGVHPALLDAVLHAVVI----AGDPDELALPFAWQGVSLHA
Rv2048c|M.tuberculosis_H37Rv        PEAAGGVGGFGVHPALLDAVLHAVVI----AGDPDELALPFAWQGVSLHA
MUL_2266|M.ulcerans_Agy99           PEAAGSTSGFGVHPALLDAALHTAVI----ANPDADLVLPFSWQGVSLHA
MAV_2450|M.avium_104                PDAAGGVTGFGVHPALLDAAMHALIVGHQIAGDTDEVALPFAWQGVSLHA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               PADIETHG-YGIHPALLDAALHPLTAALADTNTNSGPQLPFAIAGITLHA
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           TGASAVRARIAPAGPS------AVSVELADGLGLPVLSVASMVARPVTER
Rv2048c|M.tuberculosis_H37Rv        TGASAVRARIAPAGPS------AVSVELADGLGLPVLSVASMVARPVTER
MUL_2266|M.ulcerans_Agy99           AGAASVRVRIAPVGPS------SVSVELADDLGLPVLSVKAMVARPVSEQ
MAV_2450|M.avium_104                AGASAVRARLAPAQAPGTAASRAVSLELADGLGLPVLSVRAMVARSVSER
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               TGASRMHVQLEPTATD------TFRLSATDPVGAPVITIDSLTVRSLPDT
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------GTVDDPFTFDVLNRLAAQ
MAB_0939|M.abscessus_ATCC_1997      --------------------------------GVDGDQQTLNVLTKLAAQ
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------GETVDEQTLRVLNKLAAR
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------GPTGSAQTVDVLSKLAAR
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           QLLAAVSGSGPDRLFEVIWSPA----------------------------
Rv2048c|M.tuberculosis_H37Rv        QLLAAVSGSGPDRLFEVIWSPA----------------------------
MUL_2266|M.ulcerans_Agy99           QMRAVVSASGPDRLFEVVWTPM----------------------------
MAV_2450|M.avium_104                QLRAAVSAAGPDRLFEVAWAPV----------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               DLTQPPTHKAQQGIFELTWPALPAETFPATGVLPPWALISPHPENLSPDL
Mflv_0405|M.gilvum_PYR-GCK          HNQQRSTESIADDRYQIRWETA----------------------------
MAB_0939|M.abscessus_ATCC_1997      HNLQRTTQTIADDRYQFRWEKS----------------------------
MSMEG_0408|M.smegmatis_MC2_155      HNQQRSTHVDPDARYEIRWDAI----------------------------
Mvan_1003|M.vanbaalenii_PYR-1       HRQQRGAQSIADARYQIRWEKS----------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ---------SAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQALAAVQS
Rv2048c|M.tuberculosis_H37Rv        ---------SAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQALAAVQS
MUL_2266|M.ulcerans_Agy99           ---------TVAAT-DAAPAYELFESIAADGDPLSGTYQRTHQALAAVQS
MAV_2450|M.avium_104                ---------TVPAAHGEPPVHQVFESLAAEGDPVGESYRRTHEALAAVQS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               NQSPTYPNLTALPTCPPLVIWDLTTPQPPQSDLLHQVHTLTQHTLAGLQN
Mflv_0405|M.gilvum_PYR-GCK          -----------------------------------AEPPVGADAADGITW
MAB_0939|M.abscessus_ATCC_1997      -----------------------------------PTPLSGSQAAGGVTW
MSMEG_0408|M.smegmatis_MC2_155      -----------------------------------ASAAASTGAAA--DW
Mvan_1003|M.vanbaalenii_PYR-1       -----------------------------------EAPGAARPTTEATTW
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           WLT--DHESGVLVVATRGAMALPREDVA-DLAGAAVWGLVRSAQTEHPGR
Rv2048c|M.tuberculosis_H37Rv        WLT--DHESGVLVVATRGAMALPREDVA-DLAGAAVWGLVRSAQTEHPGR
MUL_2266|M.ulcerans_Agy99           WLT--EHDSGVLVVATRGAMALAGEDVT-DLAGAAVWGLVRSAQTENPGR
MAV_2450|M.avium_104                WLT--EHDSGVLVVVTRGAMALAGEDVT-DLSGAAVWGLVRSAQTEHPGR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               WLNRSDTLQAHLVVLTRHAVTTSPHDLAPDPAQAATAALIHTTQNEHPNR
Mflv_0405|M.gilvum_PYR-GCK          LLVGDDTDATRPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADA
MAB_0939|M.abscessus_ATCC_1997      LLVADAAGAAQPLLDVLTARGQQHRVLALPVSDADEAELVEALRSAADED
MSMEG_0408|M.smegmatis_MC2_155      ILVGDDTAAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAG-
Mvan_1003|M.vanbaalenii_PYR-1       LLVTHDSRAAQPIAEVLERRGHPYHIVGLPGSDADAAPAEEALRATVSQ-
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           IVLVDSDAATDDAAIAM---------ALATGEPQVVLRGGQVYTARVRGS
Rv2048c|M.tuberculosis_H37Rv        IVLVDSDAATDDAAIAM---------ALATGEPQVVLRGGQVYTARVRGS
MUL_2266|M.ulcerans_Agy99           LVLVDSDAAVDAAAVAT---------ALAVGEPQVVLRNGQPYTARVHAS
MAV_2450|M.avium_104                IVLIDSDAALDDSALTA---------ALATGEPQVLLRDGTVYTARVHGS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ITLIDIDNTPTTSQTLTNILTTLTNPTSAPTEPQLALRHGTPHTPRLTP-
Mflv_0405|M.gilvum_PYR-GCK          TDLRIVHVAALDAAESD---------------------------------
MAB_0939|M.abscessus_ATCC_1997      SALRIVHVAALAGQGS----------------------------------
MSMEG_0408|M.smegmatis_MC2_155      -ELYVVHIAAGDGAAA----------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       PRPHILYLAALEEPGG----------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           RAADAILVPPGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMR
Rv2048c|M.tuberculosis_H37Rv        RAADAILVPPGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMR
MUL_2266|M.ulcerans_Agy99           RAADGILVPPVDGPWRLGLSSAGTFENLQLEPVPNAGAPLGPGQVRVAMR
MAV_2450|M.avium_104                RAVDGIMTPPEDRPWRLGISSAGTFENLQLEPVPNPDAALQPGQVRVALR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ---TQVLTPPAAPNWELATTGKGDLANLALLPTP-PHTELGPGQIRVAVR
Mflv_0405|M.gilvum_PYR-GCK          ----------------TSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMW
MAB_0939|M.abscessus_ATCC_1997      ----------------SSAQSLLRIQHQVLGGTRRLFRAAAAAELRAPIW
MSMEG_0408|M.smegmatis_MC2_155      -----------------PMRDLLRVQHRTLGGLRRLFRAANDAELRSPIW
Mvan_1003|M.vanbaalenii_PYR-1       ----------------SAAETLGWMQHRVLAAARRLFQLAATAGARAPIW
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AIAANFRDIMITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFF
Rv2048c|M.tuberculosis_H37Rv        AIAANFRDIMITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFF
MUL_2266|M.ulcerans_Agy99           AIAANFRDIMITLGMFTHDALIGGEGAGVVVEIGPEVTEFAVGDAVYGFF
MAV_2450|M.avium_104                AIATNFRDVMITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVYGFF
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               AAGLNFRDVVVALGAIGEEG-LGGEAAGIIIDTGPDVTAFRRGDAVMGLF
Mflv_0405|M.gilvum_PYR-GCK          LVTR----------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      IVTR----------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      LVTR----------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       LITA----------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           PD-GSGTLVAGDVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQP
Rv2048c|M.tuberculosis_H37Rv        PD-GSGTLVAGDVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQP
MUL_2266|M.ulcerans_Agy99           PD-GSGTLVAGDVRLLLPKPADWSYAEAAAISAVFTTAYYAFVHLANVQP
MAV_2450|M.avium_104                PD-GSGTLVPGDVRLLQHKPTHWSYPEAAGISAVFTTAYMAFIHLADVKP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               PNNAFAATAVTDHRMVVPIPAGWSFAAAASIPVAFLTAYGAMVELGALAA
Mflv_0405|M.gilvum_PYR-GCK          ----GAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGGTSDE
MAB_0939|M.abscessus_ATCC_1997      ----GAQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDAGTDE
MSMEG_0408|M.smegmatis_MC2_155      ----DGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADT-E
Mvan_1003|M.vanbaalenii_PYR-1       ----GAQRITGDETVEPAQTSLWGFGRAAALEQPELWGGLADVTTGDAEE
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           GQRVLIHAGTGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHI
Rv2048c|M.tuberculosis_H37Rv        GQRVLIHAGTGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHI
MUL_2266|M.ulcerans_Agy99           GQRVLVHAATGGVGMAAVQLARHLGLEVYATASKGKWDILRAMGFDEDHI
MAV_2450|M.avium_104                GQRVLVHAAAGGVGMAAVQLARHLGLEVFATASRGKWDTLRAMGFDDDHI
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GRRVLIHAGAGGVGQAAIQIARHFGAEVYATAHPSKHHVLKALGVSGDRI
Mflv_0405|M.gilvum_PYR-GCK          WSRLLNRIAATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLR--
MAB_0939|M.abscessus_ATCC_1997      WAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVR--
MSMEG_0408|M.smegmatis_MC2_155      WPRLIARITSPRDG---EDQIALRGDAVYAPRLVRRTGEPSDTPLPVR--
Mvan_1003|M.vanbaalenii_PYR-1       WSALIDHIVAAPTS---EDQIAVRGREIHVARLTRCAEKANAAALELR--
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           SDSRSLEFEDKFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMG
Rv2048c|M.tuberculosis_H37Rv        SDSRSLEFEDKFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMG
MUL_2266|M.ulcerans_Agy99           SDSRSLEFEEKFREVTGGRSVDVVLDSLAGEFVDASLRLLGPGGVFLEMG
MAV_2450|M.avium_104                GDSRTLEFEDKFRSATGGAGMDVVLDSLAGEFVDASLRLVAPGGVFLEMG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ASSRTFDFVDVFNQGTNGEGMDLVLNSLAGDFVDNSLRLLSQGGRLIEIG
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           KTDIRDPGVIAQQYPGVRYRAFDLFEAGPDRIAQILAELATLFGDGVLRP
Rv2048c|M.tuberculosis_H37Rv        KTDIRDPGVIAQQYPGVRYRAFDLFEPGRPRMHQYMLELATLFGDGVLRP
MUL_2266|M.ulcerans_Agy99           KTDIRDPGVIAQEYPGVRYRAFDLFEPGRPRMHQYMLDLAGLFDAGVLRP
MAV_2450|M.avium_104                KTDIRDPGVVAREYPGVRYRAFDLFEPGRPRMRQWMVELAGLFDAGVLNP
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               KTDIRVPNEVAAAHPGVIYRTYDLSSETPDRISQLWAALIEMISAGVLRP
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           LPVTTFDVRRAPAALRYLSQARHTGKVVMLMPG----SWAAGTVLITGGT
Rv2048c|M.tuberculosis_H37Rv        LPVTTFDVRRAPAALRYLSQARHTGKVVMLMPG----SWAAGTVLITGGT
MUL_2266|M.ulcerans_Agy99           LPVTAFDVRRAPAALRYLSQARHVGKVVMTMPADQGGALGGGTVLITGGT
MAV_2450|M.avium_104                LPVTTFDIRRGRAALRYLSQARHIGKVVMTVPG----ALSAGTVLITGGT
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               LPTTSYGLLQATQALRHMSQGRHTGKIVLLPPG---VFNSEGTVLVTGGT
Mflv_0405|M.gilvum_PYR-GCK          ---------------------------------------ADATYLVTGGL
MAB_0939|M.abscessus_ATCC_1997      ---------------------------------------SDATYLVTGGL
MSMEG_0408|M.smegmatis_MC2_155      ---------------------------------------EDRTYLVTGGL
Mvan_1003|M.vanbaalenii_PYR-1       ---------------------------------------REATYLVTGGL
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           GMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVV
Rv2048c|M.tuberculosis_H37Rv        GMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVV
MUL_2266|M.ulcerans_Agy99           GMAGSALARHLVAHHGVAHLVLISRRGPAAPGATELVAELSAAGAQVEVV
MAV_2450|M.avium_104                GMAGSTLARHLVTGHGVRDLALLSRTGPDAPGAAEFVAELEAAGARVQVI
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               GMLGGVFAERLVAHYGARHLLLVSRSGPDAAGADELYQRLTQLGAQVTIT
Mflv_0405|M.gilvum_PYR-GCK          GSLGLEIAGYLAANG-AGHLVLTSRRTPDEAAASRIEALRERHGCEVRVV
MAB_0939|M.abscessus_ATCC_1997      GSIGLEIAGYLAGRG-AKHLVLTSRREPGEAARQRIDALAA-QGCEVRAV
MSMEG_0408|M.smegmatis_MC2_155      GAIGLEVAGYLASHG-AGHVVLTSRREPGDDARRRLDGLREQYACDVRVI
Mvan_1003|M.vanbaalenii_PYR-1       GALGLEVAEFLASHG-AGHLVLTGRRSASDTVRQRIDAMRERFDCQVLVA
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVV
Rv2048c|M.tuberculosis_H37Rv        ACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVV
MUL_2266|M.ulcerans_Agy99           ACDAADRPALAKVIAENPAQRP-LSAVVHAGGVLDDAVISSLTPERVDTV
MAV_2450|M.avium_104                ACDAADRAALAGVIAGISAERP-LSGVIHAAGVLDDAMITSLTPERIDAV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ACDTSNPDELAAVLAGIPPQHP-LRAVVHTAGIVDDAVTTELTHEQLDTV
Mflv_0405|M.gilvum_PYR-GCK          TADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVDRV
MAB_0939|M.abscessus_ATCC_1997      TADVADGHDVARLLAGIQAELPPLAGIVHAAGEIGTTPLSDLEDAEVDRV
MSMEG_0408|M.smegmatis_MC2_155      TADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRV
Mvan_1003|M.vanbaalenii_PYR-1       TADVADRDDVARLFSTMRSELPPLAGIVHAAGEIGTSPLRTLDDAEMDRV
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           LRSKVDAAWHLHELTRDLD--VSAFVMFSSMAGLVGSSGQANYAAANSFL
Rv2048c|M.tuberculosis_H37Rv        LRSKVDAAWHLHELTRDLD--VSAFVMFSSMAGLVGSSGQANYAAANSFL
MUL_2266|M.ulcerans_Agy99           LRAKVDAAWNLHELTRDLD--LSAFVMFSSMAGVVGSSGQANYAAANTFV
MAV_2450|M.avium_104                LRAKVDAAWNLHELTRDMN--LSAFVMFSSMAGLVGSSGQGNYAAANSFL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               LTAKADTAWHLHQLTTDAD--LDAFVVFSSVAGVLGAPGQANYAAANAFL
Mflv_0405|M.gilvum_PYR-GCK          FAGKVWGAWHLSEATSDLQ--LDFFISTSSIASVWGGFGQAAYGAANAFL
MAB_0939|M.abscessus_ATCC_1997      FAGKVWGAWHLSEAAAGLK--LDFFINTSSIAAVWGGYGQTAYSAANAFL
MSMEG_0408|M.smegmatis_MC2_155      FAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFL
Mvan_1003|M.vanbaalenii_PYR-1       FAGKVWGAVYLCEEVADMG--LDFFLATSSIASVWGSHGQTAYGAANAFL
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           DALAAHRRAHGLPAISLGWGLWDQASAMTSGLDAADLARLGREGVLALST
Rv2048c|M.tuberculosis_H37Rv        DALAAHRRAHGLPAISLGWGLWDQASAMTGGLDAADLARLGREGVLALST
MUL_2266|M.ulcerans_Agy99           DGLAAHRRAHGLPAISLGWGLWDQASDMTGGMDAADRARLGREGVLALSS
MAV_2450|M.avium_104                DALAAHRRAHGLPAISLAWGLWDQASAMTGGLDAADLARLGRDGILALSS
MLBr_00135|M.leprae_Br4923          ---------------------------MTASVEGADQK------------
MMAR_3798|M.marinum_M               DALAHQRHRNHLPATSLAWGYWQTTSGMTAHLDTVDQARLTRNSLTPITT
Mflv_0405|M.gilvum_PYR-GCK          DGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLEQRGIKTLSPADALA
MAB_0939|M.abscessus_ATCC_1997      DGLAWRLREQGIAGTSVNFGPWSAGMADAESRARLEQRGIKTLSPTDALA
MSMEG_0408|M.smegmatis_MC2_155      DGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQRGVRTLSPAEALA
Mvan_1003|M.vanbaalenii_PYR-1       DGLADSLRARGIPGISVNFGPWAAGMADAKAREQLSRRGVKTLAPADALA
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           AEALELFDTAMIVDEPFLAPARIDLTALRAHAVAVPPMFSDLASAPTRRQ
Rv2048c|M.tuberculosis_H37Rv        AEALELFDTAMIVDEPFLAPARIDLTALRAHAVAVPPMFSDLASAPTRRQ
MUL_2266|M.ulcerans_Agy99           DEAMELFDTALIVNQAFLAPARIDLAALRAHAVAVPPMFSDLVSAPTRRQ
MAV_2450|M.avium_104                DEAMELFDTALIVDEPFLAPARIDLGALRAHAVAVPPMFADLVNAPTRRR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               EHGLAMFDVALACQHPCLVPAPLNTQVLAGYARQNALPAILSAVTTTRR-
Mflv_0405|M.gilvum_PYR-GCK          GLSDAVISAAP---HPVVARVDWSRFLPLYQQAGRRGFLAELERELPAAP
MAB_0939|M.abscessus_ATCC_1997      GLADVVAASGSNAVQGVIARIDWARFLPLYQQAGKRGFLAELDREVPSHL
MSMEG_0408|M.smegmatis_MC2_155      GMADVVAGPVQ----GVVAKIDWSRFLPLYQQAGRRAFLSELESELPAAA
Mvan_1003|M.vanbaalenii_PYR-1       GMADVIAASTA---HAVVARIDWATFLPVYQLQRRRAFLSQLEREVPDVP
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           VDDSVAAAKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAI
Rv2048c|M.tuberculosis_H37Rv        VDDSVAAAKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAI
MUL_2266|M.ulcerans_Agy99           IDAALATAKSKSALAHRLHGLPELEQHAVVLDLVRSHIATVLGTITPEAI
MAV_2450|M.avium_104                VDDSLAAAKSKSALAHRLDGLPEAEQHAVLLELVRSHIATVLGSPTAEAI
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ----QATTTNTETFTSRLASQTPQQQLAILSDLVTDMTAAVLAHPDSAAL
Mflv_0405|M.gilvum_PYR-GCK          AQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTRVDAAEI
MAB_0939|M.abscessus_ATCC_1997      A--GVAGAQSGSTQLVERLANAPVQQRKKLLTDYLRDAVAEVTRVDVSEI
MSMEG_0408|M.smegmatis_MC2_155      TGAAAPATVPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEI
Mvan_1003|M.vanbaalenii_PYR-1       D--ASAPAPSGTTRFVEELTLAPVEQRRKLVLEYLRAAVAEVTRVDAAEI
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           DPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIR
Rv2048c|M.tuberculosis_H37Rv        DPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIR
MUL_2266|M.ulcerans_Agy99           DPDKAFQELGFDSLTAVEMRNRIKTVTGLSLSPTLIFDYPTPNGLANYIR
MAV_2450|M.avium_104                DPDKAFQELGFDSLTAVEMRNRLKTATGLALSPTLIFDYPTPNALAGYIR
MLBr_00135|M.leprae_Br4923          -----------------------------------------SEKLISYLK
MMAR_3798|M.marinum_M               DADLPFKDLGIDSLSALELRNSLARHTGLTLSATLVFDHPTPTAIAHHLV
Mflv_0405|M.gilvum_PYR-GCK          REDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYLL
MAB_0939|M.abscessus_ATCC_1997      REDAGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLL
MSMEG_0408|M.smegmatis_MC2_155      RDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLL
Mvan_1003|M.vanbaalenii_PYR-1       RDEAGFFDLGMDSLMAIELRRRLEQGLGKELPVTLAMDHPHLSDAAEYVL
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           TELAGLPQEIK----HTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDM
Rv2048c|M.tuberculosis_H37Rv        TELAGLPQEIK----HTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDM
MUL_2266|M.ulcerans_Agy99           AELAGAPQEVK----HTPAVRVTGDDPIAIVGMSCRYPGGIESPDDLWDM
MAV_2450|M.avium_104                TELAGAPQETT----HAPVVRATDDDPIAIVGMSCRFPGGVDSPEALWQM
MLBr_00135|M.leprae_Br4923          KVVVELDETRA----RLREYEQRATEPVAVVGIGCRFPGGVDSPDRLWDV
MMAR_3798|M.marinum_M               DQLSAAAPPAP----VATPVKANAEEPVVVVGMACRLPGGIESAAGLWDV
Mflv_0405|M.gilvum_PYR-GCK          GDVLGLTEAAT-APKAATVVSTAADEPIAIVAVSCRFPG-APNPEAFWDL
MAB_0939|M.abscessus_ATCC_1997      GDVLGLAEQAKPAAQLASAVTGRTDEPIAIVAVSCRFPG-APDPEAFWDV
MSMEG_0408|M.smegmatis_MC2_155      VEVLGLGEQTN--VRQASTVTARTDDPIAVVAVSCRFPG-APDPESFWEL
Mvan_1003|M.vanbaalenii_PYR-1       GDVLGLSEHTV--AQPDTPSTVRTDDPIAIVGMACRFPG-ADDTDAFWSV
TH_2454|M.thermoresistible__bu      -------------MSVDVTAKARPDDPIAIIGIGCRLAGRITSPEEFWGF
                                                             :*:.::.:.** .*   ..  :* .

Mb2074c|M.bovis_AF2122/97           LIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPA
Rv2048c|M.tuberculosis_H37Rv        LIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPA
MUL_2266|M.ulcerans_Agy99           LMARRDVLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFEPA
MAV_2450|M.avium_104                VAEGRDVLSEFPTDRGWDLAGVYNPDPDVPGTCYTRTGGFVDNVADFDPA
MLBr_00135|M.leprae_Br4923          VSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKTYTRWGAFLDDAAGFDAG
MMAR_3798|M.marinum_M               VSGAADVMGAFPTDRGWDVAGLFDPDPDSVGKTYTRYGGFISSAAEFDAE
Mflv_0405|M.gilvum_PYR-GCK          LSGGVDAIREVPEDR-FDIDEFYDPDPDAAGKTYTRYGGFLDHIDEFDPE
MAB_0939|M.abscessus_ATCC_1997      LSGGVDAIREVPEDR-FDIDEFYDPDPEVAGKTYTRFGGFLDGIDGFDPE
MSMEG_0408|M.smegmatis_MC2_155      LAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRFGGFLDGIDGFDPE
Mvan_1003|M.vanbaalenii_PYR-1       LAEGADLIREIPDDR-FDINEFYDPDPEAAGKIYSRYGGFLDGVDGFDPE
TH_2454|M.thermoresistible__bu      LLAGGSNVREIPAER-WEPYLRRDPRNAAVLREITPWGTFLDDLAGFDAE
                                    :    . :  .* :* ::     :*         :  * *:.    *:. 

Mb2074c|M.bovis_AF2122/97           FFGVGPSEALAMDPQQRMLLELSWEALERAGIDPTGLRGSATGVFAGVMT
Rv2048c|M.tuberculosis_H37Rv        FFGVGPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATGVFAGVMT
MUL_2266|M.ulcerans_Agy99           FFGVGPSEALAMDPQQRMFLELSWEALERAGIEPGGLRGSATGVFAGVMT
MAV_2450|M.avium_104                FFGIAPSEALAMDPQQRMFLELSWEALERAGIDPVKLRGSATGMFAGVYT
MLBr_00135|M.leprae_Br4923          FFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDPLSLRGSATGVFTGIFA
MMAR_3798|M.marinum_M               FFGISAREAAAMDPQQRVLLEVCWEALEHAGIEPGTLEGSNTGVFIGAYA
Mflv_0405|M.gilvum_PYR-GCK          FFGLSPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTGVFVGVAA
MAB_0939|M.abscessus_ATCC_1997      FFGISPREAVWIEPQQRLMLETVWEGLERAGYSPAALRGSRTGIFAGVGA
MSMEG_0408|M.smegmatis_MC2_155      FFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAA
Mvan_1003|M.vanbaalenii_PYR-1       FFGISPREAVWIDPQQRLVLETAWEGLERAGYSAAALRGSRSGVYVGVGA
TH_2454|M.thermoresistible__bu      FFGVSPREAELTDPQQRLALEVSWEALEHAGVPPRSLAGTDTAVLMGVNS
                                    ***:.. *.   :**:*: **  **.** **  .  * *: :.:  *  :

Mb2074c|M.bovis_AF2122/97           QGYGMFAA----EPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACS
Rv2048c|M.tuberculosis_H37Rv        QGYGMFAA----EPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACS
MUL_2266|M.ulcerans_Agy99           QGYGMFAA----EPVEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACS
MAV_2450|M.avium_104                QGYGMGAA----PIAEGFRLTGQSSSVASGRVSYVLGLEGPAVSVDTACS
MLBr_00135|M.leprae_Br4923          PSYGSRDT----GGLQGYGLTGTAVSVASGRVSYVLGLEGPAVSVDTACS
MMAR_3798|M.marinum_M               QRYGDSDS----DSGEGFALTGGATSVASGRVAYVLGLQGPAITVDTACS
Mflv_0405|M.gilvum_PYR-GCK          NEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTACS
MAB_0939|M.abscessus_ATCC_1997      NEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEGPAVAVDTACS
MSMEG_0408|M.smegmatis_MC2_155      NEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACS
Mvan_1003|M.vanbaalenii_PYR-1       NEYSHLLSGGSLDGIEAQFITGNALNVIAGRVSFTLGLEGPAVAVDTACS
TH_2454|M.thermoresistible__bu      DDYGRLLMED-LPGIEAWTGIGTSLCGIANRVSHLLDLRGPSVALDAACA
                                      *.           :     *      :.**:. *.:.**::::*:**:

Mb2074c|M.bovis_AF2122/97           SSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDGRC
Rv2048c|M.tuberculosis_H37Rv        SSLVALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDGRC
MUL_2266|M.ulcerans_Agy99           SSLVALHMAVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLSADGRC
MAV_2450|M.avium_104                SSLVALHMAVQSLRSGECDLALAGGVTVNATPDIFVEFSRMRGLSVDGRC
MLBr_00135|M.leprae_Br4923          SSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRC
MMAR_3798|M.marinum_M               SSLVAAHLACQSLRNGESSLALAGGVTIMATPAPFIEFARQRGLAADGRC
Mflv_0405|M.gilvum_PYR-GCK          SSLVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVGRC
MAB_0939|M.abscessus_ATCC_1997      SALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGRC
MSMEG_0408|M.smegmatis_MC2_155      SALVAVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRC
Mvan_1003|M.vanbaalenii_PYR-1       SSLVAVHQACQGLQSGDCDLALAGGVNVLLSPATTIATSRARMLSPDGRC
TH_2454|M.thermoresistible__bu      ASLVAVHNACQLLRAGETGLAIAGGVSALIGPGLTRVLDKAGATAPDGRC
                                    ::*** * *   *: *: .:*:****.    *       :    :  ***

Mb2074c|M.bovis_AF2122/97           KAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASN
Rv2048c|M.tuberculosis_H37Rv        KAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASN
MUL_2266|M.ulcerans_Agy99           KAFAGAADGTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQDGASN
MAV_2450|M.avium_104                KAYAGAADGTGFSEGGGMLVVERLSDARRLGHPVLAVVRGSAVNQDGASN
MLBr_00135|M.leprae_Br4923          KAFARAADGTGWGEGAGVVVLERLSDAQRLGHTVLAVVRGSAVNQDGASN
MMAR_3798|M.marinum_M               KAFAAAADGTGWGEGAAVLVLERLSDARRNRHPVLAVIAGSAVNQDGASN
Mflv_0405|M.gilvum_PYR-GCK          KTFDASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGASS
MAB_0939|M.abscessus_ATCC_1997      KTFDASADGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASS
MSMEG_0408|M.smegmatis_MC2_155      KTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASS
Mvan_1003|M.vanbaalenii_PYR-1       KTFDAAADGYVRGEGCGILVLKRLSDAVRDGDRIQAVIRGSAVNQDGASG
TH_2454|M.thermoresistible__bu      KSFDASADGYGRGEGAAVVILKRLPDALRDGDRVIAVIRGGAVAQDGRTV
                                    *::  :***   .** .:::::**.** *  . : *:: ..:* *** : 

Mb2074c|M.bovis_AF2122/97           GLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALL
Rv2048c|M.tuberculosis_H37Rv        GLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALL
MUL_2266|M.ulcerans_Agy99           GLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALL
MAV_2450|M.avium_104                GLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALL
MLBr_00135|M.leprae_Br4923          GLTAPNGLAQQRVIQAALTNAGLSSADVDVVEAHGTATTLGDPIEAQALL
MMAR_3798|M.marinum_M               GLSAPNGPAQQRVIAQAAANAGIALDQVDVVEAHGTGTTLGDPIEAGALI
Mflv_0405|M.gilvum_PYR-GCK          GLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQAAA
MAB_0939|M.abscessus_ATCC_1997      GLTVPNGGAQQRLIGSVLARAGLVGGDVDYLEAHGTGTPLGDPIEVQAAA
MSMEG_0408|M.smegmatis_MC2_155      GLTVPNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQAAA
Mvan_1003|M.vanbaalenii_PYR-1       GLTVPNGGAQQRVIAAALTRAGLSGSDIDYLEAHGTGTSLGDPIEVQAAG
TH_2454|M.thermoresistible__bu      GIMSPNGAAQRDLFRHTCEITGTSPATVDFVEAHGTGTPTGDPVELDALA
                                    *:  *** :*: :.  .   :*     :* :*.***.*. ***:*  *  

Mb2074c|M.bovis_AF2122/97           ATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELL
Rv2048c|M.tuberculosis_H37Rv        ATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELL
MUL_2266|M.ulcerans_Agy99           ATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVL
MAV_2450|M.avium_104                ATYGQDRGQP------LWLGSIKSNMGHTQAAAGVAGVIKMVLAMRHELL
MLBr_00135|M.leprae_Br4923          ATYGQGRPAD----QPLWVGSIKSNMGHTQAAAGVAGVIKMVQAMRHHVM
MMAR_3798|M.marinum_M               ATYGTHRDPE----HPLWLGSVKSNIGHTQAAAGAAGLIKMIQAMRHGVL
Mflv_0405|M.gilvum_PYR-GCK          AAYAGARDAD----RPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHETL
MAB_0939|M.abscessus_ATCC_1997      AAYGGSRDAD----RPLLMGSVKSNIGHTESASGAAGLIKVVLSLQNGVL
MSMEG_0408|M.smegmatis_MC2_155      AAYGAGRDAD----RPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVL
Mvan_1003|M.vanbaalenii_PYR-1       AVLGAGRDPD----RPLLMGSVKTNVGHLESASGVAGLIKVVLSLQHEML
TH_2454|M.thermoresistible__bu      AVYGAAHGPD----DPCRVGSVKPNTGHLEGGAGVVGLIKAALALQHGVI
                                    *. .  :           :**:*.* ** :..:*..*:**   ::::  :

Mb2074c|M.bovis_AF2122/97           PATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTRRAGVSSFGISG
Rv2048c|M.tuberculosis_H37Rv        PATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTRRAGVSSFGISG
MUL_2266|M.ulcerans_Agy99           PATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGISG
MAV_2450|M.avium_104                PATLHVDEPSPHVDWSAGAVSLLTEAQPWP----GERPRRAGVSSFGISG
MLBr_00135|M.leprae_Br4923          PATLHVDEPSPRVDWTTGAVSVLTEARDWS---VEGRPRRAGVSSFGISG
MMAR_3798|M.marinum_M               PKTLHVNAPTPQVDWSAGTVRLLTETMPWP---DTDHLRTAAVSSFGVSG
Mflv_0405|M.gilvum_PYR-GCK          PQSLHFDTPSPHIPWDSLPVRVVDTAMPWQ---PNGRPRRAGVSSFGFTG
MAB_0939|M.abscessus_ATCC_1997      PQSLHFDNPSPHIPWESLPVRVVDKAIPWQ---ANGRPRRAGVSSFGFTG
MSMEG_0408|M.smegmatis_MC2_155      PQSLHFENPSPHIPWDALPVRVIDEPVPWQ---TNGRVRRAGVSSFGFTG
Mvan_1003|M.vanbaalenii_PYR-1       PRHLHFKTPSPHIPWDRLAVRVVAEPTPWR---ADGRPRRAGVSSFGFSG
TH_2454|M.thermoresistible__bu      PPTAGIRELTPAVDWATNGLHVPTTVEPFPR--RADSPRRAAVCSYGYGG
                                    *    .   :* : *    : :      :         * *.*.*:*  *

Mb2074c|M.bovis_AF2122/97           TNAHVIIEAVP---------------VVPRR-EAGWAGPVVPWVVSAKSE
Rv2048c|M.tuberculosis_H37Rv        TNAHVIIEAVP---------------VVPRR-EAGWAGPVVPWVVSAKSE
MUL_2266|M.ulcerans_Agy99           TNAHVIVEAAP---------------RVEVGGSSGGAVPVVPWVVSAKSG
MAV_2450|M.avium_104                TNAHVIIEAVP---------------AVEPAHADAPALPVLPWVVSAKSA
MLBr_00135|M.leprae_Br4923          TNAHVILEEAPT------------PVEASYSTADQQRLSVVPWVVSGRST
MMAR_3798|M.marinum_M               TNAHLIVQQGSPG-----------PAVAVHQASPSQECSLGVWPLSARSS
Mflv_0405|M.gilvum_PYR-GCK          TNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARSP
MAB_0939|M.abscessus_ATCC_1997      TNAHVLIEEAPQPQATP----------DEDDASTPQSAPVSVLPLSARSP
MSMEG_0408|M.smegmatis_MC2_155      TNAHVLVEEAPPQLHTADAAP----VEPAATAEAGTDDSPQVLALSARSP
Mvan_1003|M.vanbaalenii_PYR-1       TNAHVVLEEPPAQSADLRQPPTDGKDGAAGLESATAPEPAGVLPISARSP
TH_2454|M.thermoresistible__bu      TIAHLLLEEAPAVDETPAAAP-----APAADAADANSPRFHVIPVSARSG
                                    * **::::  .                                 :*.:* 

Mb2074c|M.bovis_AF2122/97           SALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGG-----
Rv2048c|M.tuberculosis_H37Rv        SALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGG-----
MUL_2266|M.ulcerans_Agy99           SALGAQAARLAAHVRSHDELDVADVGWSLAG-RSTFEHRAVVLGA-----
MAV_2450|M.avium_104                AALRAQAARLAEYVRAQGELDIADVGWTLAG-RATFEHRAVVVGG-----
MLBr_00135|M.leprae_Br4923          AALMAQASRLAFYVQADPEVDPVDVGCALAA-RSVFEHRAVVVGE-----
MMAR_3798|M.marinum_M               AGLSAQAHRLHEYLLGHSDLDLIDLAYSLATTRTHHSYRAAVTVPGCTDN
Mflv_0405|M.gilvum_PYR-GCK          EALVALAQRYETWLTAHPEADLADVCRTAGTGRSHFEHRAALVVD-----
MAB_0939|M.abscessus_ATCC_1997      EALAAVAQRYESWLAAHPDVDLEDVCLTAGRGRSHFEHRAALVVD-----
MSMEG_0408|M.smegmatis_MC2_155      EALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEYRAALVVD-----
Mvan_1003|M.vanbaalenii_PYR-1       EALTALARRYESWLTAHPDADIADVCYTAGAGRSHFEHRAALVVD-----
TH_2454|M.thermoresistible__bu      ARLARHAAALRGHLSAG--ADLTAVAATMWQRRSHEPVRAAVIAR-----
                                      *   *      : .    *   :  :    *:    **.:        

Mb2074c|M.bovis_AF2122/97           DRDRLLAGLDELAGDQLG--GSVVRGTATAAGKTVFVFPGQGSQWLGMGM
Rv2048c|M.tuberculosis_H37Rv        DRDRLLAGLDELAGDQLG--GSVVRGTATAAGKTVFVFPGQGSQWLGMGM
MUL_2266|M.ulcerans_Agy99           DRDGLLAGLDELAGDEFGG-ASVIRGVAGAAGKTVFVFPGQGSQLLGMGM
MAV_2450|M.avium_104                DRDRLLAGLDELAADDPA--ASIIRGVATPAGKTVFVFPGQGSQTLGMGR
MLBr_00135|M.leprae_Br4923          SREQLIAGLAGLAVGESG--AGVAIGQAAPLGKTVVVFPGQGAQRIGMGR
MMAR_3798|M.marinum_M               AHHDLLGGLTALAAGQTHPFVANHYCRAGQNGKTVFVFPGQGGQYPAMAA
Mflv_0405|M.gilvum_PYR-GCK          SVESARIALTDLAQNRLR--PGVVRGEHLNHPTTAWMFTGQGSQYPGMAR
MAB_0939|M.abscessus_ATCC_1997      SIQTAREGLLELAQNRLR--PGVVRGEHTNHPTTAWLFTGQGSQYPGMAR
MSMEG_0408|M.smegmatis_MC2_155      SVERAREGLAALAEGRTP--AGVVRGEHVHRPTTAWLFTGQGSQYPGMAR
Mvan_1003|M.vanbaalenii_PYR-1       SVDGARDLLAGLAEDRLG--PGAVRGVCGDPPKTAWLFTGQGSQYPGMAR
TH_2454|M.thermoresistible__bu      HPGELVAGLDAIATDTRHPAVVAGSVLPAAEAGAVWVFSGHGSHWPGMGR
                                            *  :* .                  :. :*.*:*.:  .*. 

Mb2074c|M.bovis_AF2122/97           GLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWGH--------DENLLNS
Rv2048c|M.tuberculosis_H37Rv        GLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWGH--------DENLLNS
MUL_2266|M.ulcerans_Agy99           GLHAGYPVFAEAFNTVVGELDRHLLRPLREVIWGH--------DENLLNT
MAV_2450|M.avium_104                QLHAGYPVFAEAFDAVVAELDRHLLRPLRDVIWGD--------DENVLNS
MLBr_00135|M.leprae_Br4923          ELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGA--------DAGLLDS
MMAR_3798|M.marinum_M               ELYRQHPGFATAVDECDAELRPYTGWSVRDVICQD-------PDAPSLEL
Mflv_0405|M.gilvum_PYR-GCK          ELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVP-PTETLRH
MAB_0939|M.abscessus_ATCC_1997      ELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGGK-AGEALRH
MSMEG_0408|M.smegmatis_MC2_155      ELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET-----ADLLQH
Mvan_1003|M.vanbaalenii_PYR-1       ELFDTEPVFRDTVTRCAEAIGDTLPRPLLEVLFDTDGDN-----GQTLRH
TH_2454|M.thermoresistible__bu      ELLEHEPVFAAVIDEIEPVFRAELGFSPRQALQSG-----------ELGG
                                     *    * *   .      .      .  :.:               *  

Mb2074c|M.bovis_AF2122/97           TEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLEN
Rv2048c|M.tuberculosis_H37Rv        TEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLEN
MUL_2266|M.ulcerans_Agy99           TEFAQPALFAVEVALYRLLESWGVRPDFVMGHSVGELSAAHVAGVLSLEN
MAV_2450|M.avium_104                TEFAQPALFAVEVALFRLLESWGVRPDFVMGHSIGELSAAHVAGVLSLQN
MLBr_00135|M.leprae_Br4923          TEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPAD
MMAR_3798|M.marinum_M               VEVIQPVLFAVMIALAETLRGYGIVPDAVIGHSQGEIAAAYIAGALTLAE
Mflv_0405|M.gilvum_PYR-GCK          TSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAACVAGVFSLED
MAB_0939|M.abscessus_ATCC_1997      TSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSIED
MSMEG_0408|M.smegmatis_MC2_155      TSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDD
Mvan_1003|M.vanbaalenii_PYR-1       TSYAQPALFAIEMGLARLWQARGIEPDVVLGHSVGQYAAACVAGVFGLED
TH_2454|M.thermoresistible__bu      TDRVQALTFAVQAGLAAVLRDRGVKPAAVIGHSVGEVAACVAAGVFDLAR
                                    ..  *.  **:  .*       .: *  *:*** *: :*.  **.:    

Mb2074c|M.bovis_AF2122/97           AAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLS---AEVDIAAVNGP
Rv2048c|M.tuberculosis_H37Rv        AAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLS---AEVDIAAVNGP
MUL_2266|M.ulcerans_Agy99           AAVLVAARGRLMQALPDGGAMIAVQATEQEVLPLLG---AQVSIATINGP
MAV_2450|M.avium_104                AAVLVAARGRFMQALPEGGAMIAVQATEAQVRPLLG---PDVGIAAVNGP
MLBr_00135|M.leprae_Br4923          AAMLVVARGRLMQSMPAGGTMWAVAASEDEVVSLLG---EGVGIAAINAP
MMAR_3798|M.marinum_M               AAKVVALRSAALAQLAGTGTMASVLLSPEELRPLLQPWNTQISIAAINGP
Mflv_0405|M.gilvum_PYR-GCK          GARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAA-DFPRVSVGAYNGP
MAB_0939|M.abscessus_ATCC_1997      GARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAG-EFPRVSVGAYNGP
MSMEG_0408|M.smegmatis_MC2_155      GARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAG-EFPRVSVGAYNGP
Mvan_1003|M.vanbaalenii_PYR-1       GARLVADRGRLFGGLPVGGRMVAVFTDAEVVEDFAD-EFPQVSVAAYNGP
TH_2454|M.thermoresistible__bu      GAAVACYRARGFRSVAGKGAMALVGLPFEDARQRLG-ERTDVVAAISASP
                                    .* :   *.  :  :.  * *  *                 :  .   .*

Mb2074c|M.bovis_AF2122/97           ASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAV
Rv2048c|M.tuberculosis_H37Rv        ASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAV
MUL_2266|M.ulcerans_Agy99           ASVVISGAQDAVSAVAEQLRADGRRVHRLAVSHAFHSPLMDPMIDEFATV
MAV_2450|M.avium_104                AAVVISGDHDAAVAIAERLRAEGHRVHRLSVSHAFHSPLMEPMIDEFGTV
MLBr_00135|M.leprae_Br4923          ESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEEFVRV
MMAR_3798|M.marinum_M               AHTIISGDTTAVEQFIGTCEDGGVQIRPIAVDYASHSAHVERLREHLLHE
Mflv_0405|M.gilvum_PYR-GCK          N-TVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFESY
MAB_0939|M.abscessus_ATCC_1997      N-TVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDPILDEFESY
MSMEG_0408|M.smegmatis_MC2_155      N-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDEFEAY
Mvan_1003|M.vanbaalenii_PYR-1       N-TVLAGPASDLEQIVAGCSGEGIRTTWLDTSHAFHSALLDPVLDEFESC
TH_2454|M.thermoresistible__bu      LSTVISGTVDAVGEVSAAWAEQGVMVRKVNTDVAFHSPAMDALTAELARL
                                       :::*               *     : .. * **  :: :  .:   

Mb2074c|M.bovis_AF2122/97           AAGIAIGRPTIGVISNVTGQLAGDDFGS----AAYWRRHIRQAVRFADSV
Rv2048c|M.tuberculosis_H37Rv        AAGIAIGRPTIGVISNVTGQLAGDDFGS----AAYWRRHIRQAVRFADSV
MUL_2266|M.ulcerans_Agy99           AGELTVNAPTIGIISNLTGQLAGEDFGS----AAYWKRHVRDAVRFADSI
MAV_2450|M.avium_104                AAGLAIDKPVIPIISNLTGQPAADDFGS----PEYWKCHVRDAVRFADSV
MLBr_00135|M.leprae_Br4923          AAQVEVRKPQIGLVSNVTGELAGPDFGS----PQYWGEHVSRAVRFVDSA
MMAR_3798|M.marinum_M               LADLNPQPARIPLYSTVASELSEHPLDTTAMDAEYWYRNLREPVEFYSCV
Mflv_0405|M.gilvum_PYR-GCK          AAQLQFAAPTLPLVCNRTGAVLTGQTSLD---AQYWRRHSRQPVQFAESV
MAB_0939|M.abscessus_ATCC_1997      AAQVQFAAPTLPLVCNRTGAVLTAQTPID---GQYWRRHSRQPVQFAESV
MSMEG_0408|M.smegmatis_MC2_155      AAQFQFAAPTLPLVCNRTGAVLTGQTPLD---AQYWRRHSRQPVQFAESV
Mvan_1003|M.vanbaalenii_PYR-1       AARLAYAAPTRPLVCNRTGAVVTGPGVID---AQYWRRHARQPVQFAESV
TH_2454|M.thermoresistible__bu      TSTLTPKPAAVPLYSTALADPRSTAARD----EHYWVANLRGRVRFAEAV
                                     . .    .   : ..  .               **  :    *.* .. 

Mb2074c|M.bovis_AF2122/97           RFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVT----TMSALRKDRPEP
Rv2048c|M.tuberculosis_H37Rv        RFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVT----TMSALRKDRPEP
MUL_2266|M.ulcerans_Agy99           RFAQSAGAARFLEVGPSIGLTASIEEVLSDAAVTNPVATASALRKDRPEP
MAV_2450|M.avium_104                RFAQSAGATRFLEVGPSSGLTAAIEETLADAPVV----TVSALRKDRPEP
MLBr_00135|M.leprae_Br4923          RHLQTLGATHFIESGPSSGLMGAIEQSLAPAEAV----VVSMMGKDRPEL
MMAR_3798|M.marinum_M               AQLLAHSERVFVELSPHPVLASALTDALADTGQLTQSAVVTTLRRDRPDM
Mflv_0405|M.gilvum_PYR-GCK          RTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPR--AIASLRKGVADR
MAB_0939|M.abscessus_ATCC_1997      RTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPR--AIVSLRKGVEDR
MSMEG_0408|M.smegmatis_MC2_155      RTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPR--AVASLRKGVADR
Mvan_1003|M.vanbaalenii_PYR-1       RTLADLGCSVLMEIGPQPFLIAAALRVWPESAATPR--AIPSLRKGPDAR
TH_2454|M.thermoresistible__bu      TAAAEDGHRLFLEVSAHPVVCHSMAETLALAEVGEH-AVLPVLRREQPEL
                                          .   ::* ..   :  :     .         .   : :     

Mb2074c|M.bovis_AF2122/97           ATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS-GDG
Rv2048c|M.tuberculosis_H37Rv        ATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRRFWLS-GDG
MUL_2266|M.ulcerans_Agy99           VSLVSALAGVFVAGTAVDWRAVVG--QSHFVELPTYAFERRRFWLS-GDA
MAV_2450|M.avium_104                VALVNAVAQGWVCGMDVDWRGALG--TGHLVDLPTYAFDRRRFWLS-GDG
MLBr_00135|M.leprae_Br4923          ASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPGTD
MMAR_3798|M.marinum_M               DMVASAIANLHVHGHSPSWQKIYP--GATTVELPTYAFQRRHYWLAAPTP
Mflv_0405|M.gilvum_PYR-GCK          RQIADALAAAYIGGHKPDFAALHEQ-RGVRLELPTYPFQRRRFWPKSAGM
MAB_0939|M.abscessus_ATCC_1997      RQIADALASAYVSGHRPNFAALQRH-PRRTVELPTYPFQRRRFWPKSSGT
MSMEG_0408|M.smegmatis_MC2_155      RQIADALASAYVGGHRPDFAAVHRQ-PRRPVELPTYPFQRRRFWPKASSI
Mvan_1003|M.vanbaalenii_PYR-1       RQLAEAVAAAYIAGHRLDFTGHDGG-PHRRLPLPTYPFQHRSYWPKTAGI
TH_2454|M.thermoresistible__bu      PAVAAVVGALYCHGAPVRPAFPPG--TRWATGLPGTQWQHRRFWRTPGTP
                                      :  . .     *                  **   :::* :*      

Mb2074c|M.bovis_AF2122/97           VAADAAS-------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VAADAAG-------------------------------------------
MUL_2266|M.ulcerans_Agy99           VPADAAG-------------------------------------------
MAV_2450|M.avium_104                AASDAAG-------------------------------------------
MLBr_00135|M.leprae_Br4923          GTASVSG-------------------------------------------
MMAR_3798|M.marinum_M               TPATVSDPAEVALWDAVNDDAVDTVARVLRIDNAQSMVSLGPMVRALREW
Mflv_0405|M.gilvum_PYR-GCK          AIDGRVG-------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      AIEG--G-------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      AVDG----------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       RSDG----------------------------------------------
TH_2454|M.thermoresistible__bu      PGGVGVH-------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ---LG---------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        ---LG---------------------------------------------
MUL_2266|M.ulcerans_Agy99           ---LG---------------------------------------------
MAV_2450|M.avium_104                ---LG---------------------------------------------
MLBr_00135|M.leprae_Br4923          ---LG---------------------------------------------
MMAR_3798|M.marinum_M               RKELGDRSVVGQLRYQVGWRNVTPNTFPQTRQRWLVLTLPEQSDDVWVAG
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MAV_2450|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               FSARFADSVAMLAIDPHMFDRNSLAALLADEATRNKCDGVVSFMALRERT
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ---------------------------------------------LAASE
Rv2048c|M.tuberculosis_H37Rv        ---------------------------------------------LAASE
MUL_2266|M.ulcerans_Agy99           ---------------------------------------------LQAGE
MAV_2450|M.avium_104                ---------------------------------------------LAAGD
MLBr_00135|M.leprae_Br4923          ---------------------------------------------LGSTE
MMAR_3798|M.marinum_M               HQDFRGISTALLSTLHITQAYGDSGLDLPLWVITQGGAQVNPDEDLTPSQ
Mflv_0405|M.gilvum_PYR-GCK          ----------------------------------------------ASAG
MAB_0939|M.abscessus_ATCC_1997      ----------------------------------------------GGLP
MSMEG_0408|M.smegmatis_MC2_155      ----------------------------------------------GTAA
Mvan_1003|M.vanbaalenii_PYR-1       -----------------------------------------------SSG
TH_2454|M.thermoresistible__bu      ----------------------------------------------DVDS
                                                                                      

Mb2074c|M.bovis_AF2122/97           HALLG--------------AVIDLPASGG---------------------
Rv2048c|M.tuberculosis_H37Rv        HALLG--------------AVIDLPASGG---------------------
MUL_2266|M.ulcerans_Agy99           HALLG--------------AVVELPASGG---------------------
MAV_2450|M.avium_104                HALLG--------------AVVELPASGG---------------------
MLBr_00135|M.leprae_Br4923          HALLG--------------AVVERPDSGG---------------------
MMAR_3798|M.marinum_M               SAVWGLGQSACLEHPTWWGGLVDLPVSPAPQDFNRLQAILTCQQSEDQLA
Mflv_0405|M.gilvum_PYR-GCK          SGILG--------------SGKDLASGDS---------------------
MAB_0939|M.abscessus_ATCC_1997      SGILG--------------RGEDLASGDS---------------------
MSMEG_0408|M.smegmatis_MC2_155      SGILG--------------SGKDLASGDT---------------------
Mvan_1003|M.vanbaalenii_PYR-1       SGLLG--------------SAQDLASGDI---------------------
TH_2454|M.thermoresistible__bu      HTLLG--------------GRIDVAGAVP---------------------
                                      : *                 : . .                       

Mb2074c|M.bovis_AF2122/97           --------------------------------VVLTGRLSPSVQGWLADH
Rv2048c|M.tuberculosis_H37Rv        --------------------------------VVLTGRLSPSVQGWLADH
MUL_2266|M.ulcerans_Agy99           --------------------------------VVLTGRLSLAAQGWLADH
MAV_2450|M.avium_104                --------------------------------VLLTGRLSPASQGWLADH
MLBr_00135|M.leprae_Br4923          --------------------------------VVLTGRLSLANQPWLADH
MMAR_3798|M.marinum_M               IRAAGVSARRLHKASLPQDRMRTWKISGTALVTGVTGHLGQHIARWLAQA
Mflv_0405|M.gilvum_PYR-GCK          ---------------------------------VYTSRLSVKTQPWLSDH
MAB_0939|M.abscessus_ATCC_1997      ---------------------------------VYISRLSVRSQPWLSDH
MSMEG_0408|M.smegmatis_MC2_155      ---------------------------------IYTSRLSVKSQPWLADH
Mvan_1003|M.vanbaalenii_PYR-1       ---------------------------------VHTSRLSVKTQPWLSDH
TH_2454|M.thermoresistible__bu      -------------------------------ARVWQTRLDLSTRPYPGDH
                                                                         :*.     : .: 

Mb2074c|M.bovis_AF2122/97           SVAGVTIFP-----------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SVAGVTIFP-----------------------------------------
MUL_2266|M.ulcerans_Agy99           AVGGVVIFP-----------------------------------------
MAV_2450|M.avium_104                AVGGVVLFP-----------------------------------------
MLBr_00135|M.leprae_Br4923          VIGGVVLFP-----------------------------------------
MMAR_3798|M.marinum_M               GASHLVLLSRTAAEHPQVAELEKELNSAGITTTSISVDVTDRDALAAVVA
Mflv_0405|M.gilvum_PYR-GCK          VIYGTVVVP-----------------------------------------
MAB_0939|M.abscessus_ATCC_1997      VIYGTVVVP-----------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      VIYGTVVVP-----------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       VIYGTVVVP-----------------------------------------
TH_2454|M.thermoresistible__bu      PVQGTEIVP-----------------------------------------
                                          :..                                         

Mb2074c|M.bovis_AF2122/97           ----GAGFVELAIRAGDEVGCGVVDELTLAAPLVLPASGSVAVQVVVNGP
Rv2048c|M.tuberculosis_H37Rv        ----GAGFVELAIRAGDEVGCGVVDESTLAAPLVLPASGSVAVQVVVNGP
MUL_2266|M.ulcerans_Agy99           ----GAGFVELAIRAGDEVGCRVVDELTLAAPLVLPSGGSVAVQVVVGSP
MAV_2450|M.avium_104                ----GAGFVELAIRAGDEVGCGIIDELNLAAPLVLPAGGSVAIQVVVDGP
MLBr_00135|M.leprae_Br4923          ----GAGFVELVIRAGDEVGCAGVEELVLAAPLVLHPGSGVQVQVVVAAA
MMAR_3798|M.marinum_M               ETRIEHGPIHTVVHAAAHIGLVTTAETTIDEFIKSFAAKALGAENLIAVL
Mflv_0405|M.gilvum_PYR-GCK          ------GATYAAMALAAVGTPAHAKDVFFYEPIILPEKSSREVQLTVHPS
MAB_0939|M.abscessus_ATCC_1997      ------GATYAAMALAAVGTPARAKDVFFYEPIILPEKSSREVQLTLHPL
MSMEG_0408|M.smegmatis_MC2_155      ------GATYAAMALAAVGTPARLKDVFFYEPIILPEKASREVQLTLHPA
Mvan_1003|M.vanbaalenii_PYR-1       ------GATYAAMALAAMPTPARVQEVFFYEPIILGDKDSREVQLMLHRT
TH_2454|M.thermoresistible__bu      ----------AAVLLNTFLTAAGSDIADVRLRTPVAPARTRDVQVVLQDR
                                               .:               .              :  :   

Mb2074c|M.bovis_AF2122/97           DESGVRGVSVYSRGDVGTG--WVLHAEGALRA------------GSAEPT
Rv2048c|M.tuberculosis_H37Rv        DESGVRGVSVYSRGDVGTG--WVLHAEGALRA------------GSAEPT
MUL_2266|M.ulcerans_Agy99           DDSGARAVSVYSRGDAGSD--WVLHAEGSLGS------------GSPEPA
MAV_2450|M.avium_104                DDSGARAVSVFSRADAGAG--WLLHAEGVLRA------------GSAQPA
MLBr_00135|M.leprae_Br4923          DESSRRAVSVYSRGDQSHGG-WLLNAEGLLEV------------DAAEAT
MMAR_3798|M.marinum_M               EDQPPQTFIMFSSAAATWGG-TRQGAYAAANAYIEALVTRLRGRGCRAIA
Mflv_0405|M.gilvum_PYR-GCK          VDGE-SKFQVHSRPYGERGAEWALNAEGVVASGVGD------SPAAAGDL
MAB_0939|M.abscessus_ATCC_1997      EDGSGSKFQVHSRPYGERDVDWSLNAEGTVVTGIGDDA---EPAPEAAEP
MSMEG_0408|M.smegmatis_MC2_155      DGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD------PDAAADEQ
Mvan_1003|M.vanbaalenii_PYR-1       DDADGWTFEVHSRPYGDRDADWSRNASGTVAAGVGD--------AAPDAA
TH_2454|M.thermoresistible__bu      ALALASRIVGEDTTARATAG-----------------------RDTTDRD
                                           .   .                                      

Mb2074c|M.bovis_AF2122/97           ADLAMWPPAGAVPVEVADGYQQLAERGYGYGPAFR-----GLTA------
Rv2048c|M.tuberculosis_H37Rv        ADLAMWPPAGAVPVEVADGYQQLAERGYGYGPAFR-----GLTA------
MUL_2266|M.ulcerans_Agy99           TDLSTWPPVGAVEVENADGYQQLAERGYGYGPAFR-----GLNA------
MAV_2450|M.avium_104                TDLSAWPPVGAVPVDLGDGYEQLAERGYRYGPAFR-----GLTS------
MLBr_00135|M.leprae_Br4923          VDLSLWPPEGAESVDISDAYPQLAERGYAYGPAFQ-----GLVA------
MMAR_3798|M.marinum_M               PAWGAWTDDRTTTQEVVGYFSRIGLNQISPDIAFA-----ALQQSLDVDD
Mflv_0405|M.gilvum_PYR-GCK          EDPVDEAIERLNRMRPQELFETFADLELAWGPTWS-----GSLKS-----
MAB_0939|M.abscessus_ATCC_1997      AEPVDAAIERMERMRPMELFEIFADLELAWGPTWS-----GSLKS-----
MSMEG_0408|M.smegmatis_MC2_155      SDPVDEVIERLERMRPQDLFETFADLELAWGPTWS-----GSLKS-----
Mvan_1003|M.vanbaalenii_PYR-1       ADPVDNAIERLTRTRPQQLFDAFADNDLAWGPAWC-----SSLRS-----
TH_2454|M.thermoresistible__bu      TTACDTTDRDTTACDDPGVWLTHCTARVADDHVGAEGVLD----------
                                                       :          . .                 

Mb2074c|M.bovis_AF2122/97           --------MWRRGDEVFAEV----ALPADAGVSVTGFGVHPVLLDAALHA
Rv2048c|M.tuberculosis_H37Rv        --------MWRRGDEVFAEV----ALPADAGVSVTGFGVHPVLLDAALHA
MUL_2266|M.ulcerans_Agy99           --------MWRRGDEVFAEV----ALPADAGVSVSGFGIHPVMLDAALHA
MAV_2450|M.avium_104                --------MWRRGDEIFAEV----NLPTDAGVSTTGFGVHPVMLDAALHA
MLBr_00135|M.leprae_Br4923          --------IWRRGSELFAEV----VAPT--GVVVDGMGMHPALLDAVLHA
MMAR_3798|M.marinum_M               TLITIADVDWSQFRDVFTTTGRAHALLAELGTSQPQTAEIPAIAENSHFA
Mflv_0405|M.gilvum_PYR-GCK          --------LWLGEGEAIGDILVGAELAEQLGTEPMHPVLMDLCTGVAFPA
MAB_0939|M.abscessus_ATCC_1997      --------LWLGEGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPA
MSMEG_0408|M.smegmatis_MC2_155      --------LWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVAFPA
Mvan_1003|M.vanbaalenii_PYR-1       --------LWVGTGEAVGDIAVGAELGEHLGREPIHPVLLDLCTGIAGAA
TH_2454|M.thermoresistible__bu      ----------------------EEAIRARCPQPLPAGHVVDTLAGLG---
                                                                                      

Mb2074c|M.bovis_AF2122/97           VVLSAESAERG---------------------------------------
Rv2048c|M.tuberculosis_H37Rv        VVLSAESAERG---------------------------------------
MUL_2266|M.ulcerans_Agy99           VILASDGADDFGV-------------------------------------
MAV_2450|M.avium_104                VMLASDGDDLP---------------------------------------
MLBr_00135|M.leprae_Br4923          LGLAIENTQAT---------------------------------------
MMAR_3798|M.marinum_M               AQLAKQAPQQQLATLIGLVTNVTAAVLAHPDPAVLDPDLSFKDLGIDSLS
Mflv_0405|M.gilvum_PYR-GCK          FPALLAA-EQG---------------------------------------
MAB_0939|M.abscessus_ATCC_1997      FPALLAA-EQG---------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      FPALLAA-EQG---------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       LLAAAAQ-TDA---------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MAV_2450|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ALELRNTLTRDTGLTLPATVVFDHPTPTAVAEHLLGLLSGVTGPTLAVVP
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MAV_2450|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               TRVGVDVPVAVVGMACRLPGGIESAAGLWDVVSNGIDVMSGFPLDRGWDV
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ---------------------------------------------QGSVL
Rv2048c|M.tuberculosis_H37Rv        ---------------------------------------------QGSVL
MUL_2266|M.ulcerans_Agy99           --------------------------------------------PEGSVL
MAV_2450|M.avium_104                ---------------------------------------------AGSML
MLBr_00135|M.leprae_Br4923          ----------------------------------------------TEMR
MMAR_3798|M.marinum_M               AGLFDPDPDAEGKTYTRYGGFVADVAGFDAEFFGISAREAITMDPQQRVL
Mflv_0405|M.gilvum_PYR-GCK          ---------------------------------------------VNDLY
MAB_0939|M.abscessus_ATCC_1997      ---------------------------------------------VNDLF
MSMEG_0408|M.smegmatis_MC2_155      ---------------------------------------------VNDLF
Mvan_1003|M.vanbaalenii_PYR-1       ---------------------------------------------DPELF
TH_2454|M.thermoresistible__bu      -----------------------------------------------VAA
                                                                                      

Mb2074c|M.bovis_AF2122/97           VPFSWQGVSLHAAGASAVRAR------------------------IAPVG
Rv2048c|M.tuberculosis_H37Rv        VPFSWQGVSLHAAGASAVRAR------------------------IAPVG
MUL_2266|M.ulcerans_Agy99           VPFAWQGVTLHAAGASAVRAR------------------------IAPAG
MAV_2450|M.avium_104                VPFSWQRVSLHAAGAAAVRAR------------------------IVPVS
MLBr_00135|M.leprae_Br4923          LPFCWRGVSLHAGGAGRVRAR------------------------FTSAG
MMAR_3798|M.marinum_M               LEVCWQALEHAGIDPTTLEGSDTGVFVGIGAQSYVSGHSGVEGYALTGAS
Mflv_0405|M.gilvum_PYR-GCK          LPLRYGQVSLQEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGG
MAB_0939|M.abscessus_ATCC_1997      LPLRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGG
MSMEG_0408|M.smegmatis_MC2_155      LPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGG
Mvan_1003|M.vanbaalenii_PYR-1       LPLRYGRVEVRERMPRRFYCRARWQTGGIDSETQVFDLDFLDHDGRNLGG
TH_2454|M.thermoresistible__bu      MGFGWEVLELHR--------------------------------------
                                    : . :  :                                          

Mb2074c|M.bovis_AF2122/97           PSAVSIELADGLGLP-------VLSVASMLARPVTDQQLR----------
Rv2048c|M.tuberculosis_H37Rv        PSAVSIELADGLGLP-------VLSVASMLARPVTDQQLR----------
MUL_2266|M.ulcerans_Agy99           PSAVSIELSDGLGLP-------VLSVASMLARPVTDQQLR----------
MAV_2450|M.avium_104                PSAVSIELADGLGLP-------VLSVASMVARPVTDQQLL----------
MLBr_00135|M.leprae_Br4923          ADAIAVDIADSAGLP-------VLTVRSLVTRAMTAEQLR----------
MMAR_3798|M.marinum_M               ASVASGRVAYVLGLQGPAITVDTACSSSLVATHLACQSLRNGESSLALAG
Mflv_0405|M.gilvum_PYR-GCK          VREFTVKRAPREALLRG-----LGGDATRLLYTLGWHEVPVP--------
MAB_0939|M.abscessus_ATCC_1997      IREFTVKRAPREALLRG-----LGGDATRLLYTLGWHEVAVPPVA-----
MSMEG_0408|M.smegmatis_MC2_155      IREFTVKRAPREALLRG-----LGGDATRLLYTLGWHEVPPP--------
Mvan_1003|M.vanbaalenii_PYR-1       IREFTVKRAPREALLRG-----LGADATRLIYRVGWRETSPP--------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ----------------------------AAVSSSG---PDRLFEVTWSPQ
Rv2048c|M.tuberculosis_H37Rv        ----------------------------AAVSSSG---PDRLFEVTWSPQ
MUL_2266|M.ulcerans_Agy99           ----------------------------AAVSGAG---PDRLFGVDWTAQ
MAV_2450|M.avium_104                ----------------------------AAVSNSG---PDRLFELIWSAQ
MLBr_00135|M.leprae_Br4923          ----------------------------TAVTAAGGALEQGPMDLVWSPI
MMAR_3798|M.marinum_M               GATIMATPTPFIEFARQRGLAADGRCKAFAAAADGTGWGEGAAVLVLERL
Mflv_0405|M.gilvum_PYR-GCK          -------------------------ESGDGAAPQGTWLIGGFDELAVSVP
MAB_0939|M.abscessus_ATCC_1997      ------------------------GEGEESAASIGTWLIAGFDELAAKVP
MSMEG_0408|M.smegmatis_MC2_155      ---------------------------PSADDAVGTWLIAGFDELAAKVP
Mvan_1003|M.vanbaalenii_PYR-1       ------------------------VRDDGALGPSSTWLVAGLDALADDVP
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           PSAAVEP-----------LPVCAWGTTEDS-------------AAVVFES
Rv2048c|M.tuberculosis_H37Rv        PSAAVEP-----------LPVCAWGTTEDS-------------AAVVFES
MUL_2266|M.ulcerans_Agy99           PSAELQP-----------VPVRIWGTVESEGDDDPG-------ASVVFES
MAV_2450|M.avium_104                PSTAVQP-----------VSLLNWGATELDATDTDSDS---GRFAVLFES
MLBr_00135|M.leprae_Br4923          PLSSDGHG-------GGLPSVVSWADYCAGRGNDTG--------VVVWEF
MMAR_3798|M.marinum_M               SDARRNRH-------PVLAVIAGSAVNQDGASNGLSAPNGPAQQRVISQA
Mflv_0405|M.gilvum_PYR-GCK          GCIPADR----------------TNPESLRQLLTDAHGRGLPFSGVVWRA
MAB_0939|M.abscessus_ATCC_1997      GCIPLNRE---------------TDPELLGEVLVAAKERGVPFSGVVWRA
MSMEG_0408|M.smegmatis_MC2_155      GCVPIDRN---------------TDLQVLGEVLSQAHARGAGFSGVVWRC
Mvan_1003|M.vanbaalenii_PYR-1       GSIRIGFDRIWDPDRDGRVVLDPADDEHWRRLFALADERRAPVAGVVLGV
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           VPLAG------DVVAGVYAATSS---------------------------
Rv2048c|M.tuberculosis_H37Rv        VPLAG------DVVAGVYAATSS---------------------------
MUL_2266|M.ulcerans_Agy99           VPQAG------EVVAGVYAATAA---------------------------
MAV_2450|M.avium_104                APVAG------DVVTEVYAATRA---------------------------
MLBr_00135|M.leprae_Br4923          GSASAGAQAPVDSVAAVYSATHA---------------------------
MMAR_3798|M.marinum_M               LANAGLPFTHVDVVEAHGTGTTLGDPIEAGALIATYGTHRDPEHPLWLGS
Mflv_0405|M.gilvum_PYR-GCK          ARSDGDES--DAEVAARLEAEIA---------------------------
MAB_0939|M.abscessus_ATCC_1997      AGPGATES--TTESAARLEGEIA---------------------------
MSMEG_0408|M.smegmatis_MC2_155      ATPGRKESGSASAESARLEAEIT---------------------------
Mvan_1003|M.vanbaalenii_PYR-1       TGRARPEE-PSADFAARLEAQIR---------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MAV_2450|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VKSNIGHTQHAAGAAGLIKMIQALNHAVLPATLHIDQPSPHIDWSTDTVR
Mflv_0405|M.gilvum_PYR-GCK          -------------------------------------------------E
MAB_0939|M.abscessus_ATCC_1997      -------------------------------------------------H
MSMEG_0408|M.smegmatis_MC2_155      -------------------------------------------------N
Mvan_1003|M.vanbaalenii_PYR-1       -------------------------------------------------D
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           VLDVLQSWLT-----RDGAGVLVVMTRGAVALPGEDVTDLAGAAVWGLVR
Rv2048c|M.tuberculosis_H37Rv        VLDVLQSWLT-----RDGAGVLVVMTRGAVALPGEDVTDLAGAAVWGLVR
MUL_2266|M.ulcerans_Agy99           VLEVLRSWLS-----RDGAGQLIITTRGAVALPDEDVTDLAGSAVWGLVR
MAV_2450|M.avium_104                VLPVLQSWLA-----RDGAGTLVVSTRGAMTLPGEDVTDLAGAAVWGLVR
MLBr_00135|M.leprae_Br4923          ALQVLQFWFG-----QDRAGTLVVLTRGAVGLVGEGISDLAAAAVWGMVR
MMAR_3798|M.marinum_M               LLTEATPWPE-----TEHLRTGAVSAFGVSGTNAHLIVQQAPPEVFESVP
Mflv_0405|M.gilvum_PYR-GCK          LLGAVHTVQ---GGEVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGR
MAB_0939|M.abscessus_ATCC_1997      LLSAVHTVQNSAQNGVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGR
MSMEG_0408|M.smegmatis_MC2_155      LLSAVHAAQ---GPSVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGR
Mvan_1003|M.vanbaalenii_PYR-1       VLGAVHSLS---ALGAKPAAGLWIVTERAVAAEAGEPVDPVQSALWGLGR
TH_2454|M.thermoresistible__bu      -------------------------GEGELFARVAAEPDKSAPATWAGLI
                                                                          :   .  :    

Mb2074c|M.bovis_AF2122/97           SAQTEHPG------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        SAQTEHPG------------------------------------------
MUL_2266|M.ulcerans_Agy99           SAQTEHPG------------------------------------------
MAV_2450|M.avium_104                SAQTEHPG------------------------------------------
MLBr_00135|M.leprae_Br4923          SAQSEHSG------------------------------------------
MMAR_3798|M.marinum_M               EPETARPSGQPLLRIWPVSAHTPAALTAQAERLSEYLTRHEDLSLTDLAY
Mflv_0405|M.gilvum_PYR-GCK          TAINEEPA------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      TTINEEPA------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      TTINEEPA------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       TLIAEEPG------------------------------------------
TH_2454|M.thermoresistible__bu      DAATSTAS------------------------------------------
                                          ..                                          

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MAV_2450|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               SLACTRTHHPYRAAVTVPVDTSNPGHDLAAALRALAANQPHPYVTCHHYR
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MAV_2450|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               ARQPSKTVFVFPGQGGQYPAMAAELYRQHPGFATAVDECDAELRPYTGWS
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ------------------------------------------RIVLVDSD
Rv2048c|M.tuberculosis_H37Rv        ------------------------------------------RIVLVDSD
MUL_2266|M.ulcerans_Agy99           ------------------------------------------RIVLVDTD
MAV_2450|M.avium_104                ------------------------------------------RIVLVDTD
MLBr_00135|M.leprae_Br4923          ------------------------------------------KIVLIDTD
MMAR_3798|M.marinum_M               VRDVICQDPDAPSLELVEVIQPVLFAVMIALAETLRGYGIVPDAVIGHSQ
Mflv_0405|M.gilvum_PYR-GCK          -----------------------------------------LRCRLVDCD
MAB_0939|M.abscessus_ATCC_1997      -----------------------------------------LRAKLVDGD
MSMEG_0408|M.smegmatis_MC2_155      -----------------------------------------LHCRLVDCD
Mvan_1003|M.vanbaalenii_PYR-1       -----------------------------------------LRCLLVDLD
TH_2454|M.thermoresistible__bu      --------------------------------------------TIFDGP
                                                                                 : .  

Mb2074c|M.bovis_AF2122/97           APLDDSALAAVVTTGE----PQVLWRRGEVYTARVHGSRAVGGLLVPPSD
Rv2048c|M.tuberculosis_H37Rv        APLDDSALAAVVTTGE----PQVLWRRGEVYTARVHGSRAVGGLLVPPSD
MUL_2266|M.ulcerans_Agy99           AQLDEHAVAAVLAAGE----PQVLWRNGEVYTARVHGSRAVAGLLVPPGD
MAV_2450|M.avium_104                APLDADAVAAVLAVGE----PQTLLRNGTVYTARVLGSRAVGALLVPPED
MLBr_00135|M.leprae_Br4923          SAVD---VAVLADLGE----SQLLVRCNTVHAARLS--PAPQLLALPVGE
MMAR_3798|M.marinum_M               GEIAAAYIAGALTLAE----AAKVVALRSAALAQLAGTGTMASVLLSPEE
Mflv_0405|M.gilvum_PYR-GCK          GSPQAVQALAALLSTP-VDEPELAVRQGKLLASRLLPWSRSGHLTVPRGG
MAB_0939|M.abscessus_ATCC_1997      GSPEAVQALARLLVTP-VDEPEIAVRQGKLLASRLLPWSRTGHLTVPRGS
MSMEG_0408|M.smegmatis_MC2_155      GSSEAVDLLAALLAAPGIQEPEIAVRQGKLLASRLLPWARSGHLTLPRGG
Mvan_1003|M.vanbaalenii_PYR-1       GSEDAGPALARLLGAP-GDEPELALRQGRLLVPRLLPWSRSGQLAIPRGT
TH_2454|M.thermoresistible__bu      PRLRMPARIERVHVRD-------KPPAIALLHVRRRPEGTVTDVTIAEES
                                                                     :         : :.   

Mb2074c|M.bovis_AF2122/97           R-----PWRLAMSTA---------------------GTFEN---------
Rv2048c|M.tuberculosis_H37Rv        R-----PWRLAMSTA---------------------GTFEN---------
MUL_2266|M.ulcerans_Agy99           G-----PWRLGMSTA---------------------GTFEN---------
MAV_2450|M.avium_104                G-----PWRLGMSSY---------------------GTIEN---------
MLBr_00135|M.leprae_Br4923          S-----MWRLAADGG---------------------GTLED---------
MMAR_3798|M.marinum_M               LRPLLQPWNTQISIAAINGPAHTIISGDTTAVEQFIGTCEDGGVQIRPIA
Mflv_0405|M.gilvum_PYR-GCK          D------YVLAPTER---------------------GAIDN---------
MAB_0939|M.abscessus_ATCC_1997      D------YVLAPTER---------------------GAIDN---------
MSMEG_0408|M.smegmatis_MC2_155      D------FVLAPTER---------------------GAIDN---------
Mvan_1003|M.vanbaalenii_PYR-1       D------YVLAPTER---------------------GVLDN---------
TH_2454|M.thermoresistible__bu      G-------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MAV_2450|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               VDYASHSAHVERLREHLLHELADLNPQPARIPLYSTVASELSEHPLDTTA
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           -------------------------------LRLELIPDADAPLG---PG
Rv2048c|M.tuberculosis_H37Rv        -------------------------------LRLELIPDADAPLG---PG
MUL_2266|M.ulcerans_Agy99           -------------------------------LRLEPIPDADAALQ---PG
MAV_2450|M.avium_104                -------------------------------LRLEPIPDADAPLG---PG
MLBr_00135|M.leprae_Br4923          -------------------------------LVIQPCPEVQAPLQ---AG
MMAR_3798|M.marinum_M               MDAEYWYRNLREPVEFYSCVAQLLAHSERVFVELSPHPVLASALTDALAD
Mflv_0405|M.gilvum_PYR-GCK          -------------------------------LRLTDSEVPPPAEG-----
MAB_0939|M.abscessus_ATCC_1997      -------------------------------LRITEKEVPAPDEG-----
MSMEG_0408|M.smegmatis_MC2_155      -------------------------------LRLTETDVPEPDEG-----
Mvan_1003|M.vanbaalenii_PYR-1       -------------------------------LRVSETEVTAPPEG-----
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           QVRVAVSAIAANFR-------DVMIALG---------------LYP----
Rv2048c|M.tuberculosis_H37Rv        QVRVAVSAIAANFR-------DVMIALG---------------LYP----
MUL_2266|M.ulcerans_Agy99           HVRVALSAMAANFR-------DVMIALG---------------LYP----
MAV_2450|M.avium_104                QVRVATSALAANFR-------DVMIALG---------------LYP----
MLBr_00135|M.leprae_Br4923          HMRVAVAAVGVNFR-------DVVAALG---------------MYP----
MMAR_3798|M.marinum_M               TGQLTQSAVVTTLRRDRPDMDMVASAIANLHVHGHSPSWQ--KIYPGATT
Mflv_0405|M.gilvum_PYR-GCK          YVQVRVEAAGLNFR-------DVLNVLG-----------LYP--------
MAB_0939|M.abscessus_ATCC_1997      YVQVRVEAAGLNFR-------DVLNVLG-----------LYP--------
MSMEG_0408|M.smegmatis_MC2_155      YVQVRVEAAGLNFR-------DVLNVLG-----------LYP--------
Mvan_1003|M.vanbaalenii_PYR-1       HVQVRVEAAGLNFR-------DVLNALG-----------LYP--------
TH_2454|M.thermoresistible__bu      --AVSVTLTGMGFE------------------------------------
                                       :        :.                                    

Mb2074c|M.bovis_AF2122/97           ---------------DPDAVMGVEACG----------VVIETSLNKGSFA
Rv2048c|M.tuberculosis_H37Rv        ---------------DPDAVMGVEACG----------VVIETSLNKGSFA
MUL_2266|M.ulcerans_Agy99           ---------------DPDAAMGVEGAG----------VVVETASPDGRFA
MAV_2450|M.avium_104                ---------------DPDAVMGIEASG----------VVIETASQDGRVA
MLBr_00135|M.leprae_Br4923          ---------------GQAPPLGAEGAG----------VVIEIGPEVTGVA
MMAR_3798|M.marinum_M               VELPTYPFQHRRYWLDPAPRADVSAAGLDQPEHPLLAAVTELADQDQIVL
Mflv_0405|M.gilvum_PYR-GCK          ---------------GDPGPIGGDFAG----------TVTQLGEGVTGLD
MAB_0939|M.abscessus_ATCC_1997      ---------------GDPGPIGGDFAG----------IVTQLGEGVTGVE
MSMEG_0408|M.smegmatis_MC2_155      ---------------GDPGPIGGDFAG----------TVTQLGAGVSGLE
Mvan_1003|M.vanbaalenii_PYR-1       ---------------GDPGPIGGELAG----------VVTAPGPDVDGFD
TH_2454|M.thermoresistible__bu      ---------------ELENPGGGGSSG-----------------------
                                                         .   .*                       

Mb2074c|M.bovis_AF2122/97           VG------------------------DRVMGLFPEGTGTVASTDQRLLVK
Rv2048c|M.tuberculosis_H37Rv        VG------------------------DRVMGLFPEGTGTVASTDQRLLVK
MUL_2266|M.ulcerans_Agy99           VG------------------------DRVVGLFPEGTGTIAITDHRLLVK
MAV_2450|M.avium_104                VG------------------------DRVMGLFPDGTGTVATTDQRLLVK
MLBr_00135|M.leprae_Br4923          VG------------------------DAVMG-FLGGAGPLAVVHQQLITQ
MMAR_3798|M.marinum_M               SGRLSTSAHRWLAGHQLGDTVVLPATALIDMALYAGEHTGCPTIDELVLQ
Mflv_0405|M.gilvum_PYR-GCK          VG------------------------QRVYGSMQGAFASRFNVPGQFLAP
MAB_0939|M.abscessus_ATCC_1997      VG------------------------QRVYGSMQGAFGSRFNVPAQFLAP
MSMEG_0408|M.smegmatis_MC2_155      IG------------------------QRVYGSMQGAFASRFNVPAQFLAP
Mvan_1003|M.vanbaalenii_PYR-1       VG------------------------QRVFGFAVGAFASRVNVPVQFLAP
TH_2454|M.thermoresistible__bu      -----------------------------------DLTGMLHHLRWHPVD
                                                                                      

Mb2074c|M.bovis_AF2122/97           VPAGWSHTAAATTSVVFATAHYALVDLADVQPGQRVLIHAGTGGVGMAAV
Rv2048c|M.tuberculosis_H37Rv        VPAGWSHTAAATTSVVFATAHYALVDLAAARSGQRVLIHAGTGGVGMAAV
MUL_2266|M.ulcerans_Agy99           IPAGWSDTAAATTSVVFATAFYALRDLASVQPGQRILVHAATGGVGMAAV
MAV_2450|M.avium_104                VPAGWSHTAAATASVVFATAYYALVDLADARPGQRVLVHAAAGGVGMAAV
MLBr_00135|M.leprae_Br4923          MPQGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLIHAGTGGVGMAAV
MMAR_3798|M.marinum_M               TPLTLTPDAATDLQISVAAPDEQNRRTFSVHARTSEHPHQHSTWVLHASG
Mflv_0405|M.gilvum_PYR-GCK          IPDGVSAVEAATIPAAALTVR-LSFDWAQVKSGDKVLIHAASGGVGLAAV
MAB_0939|M.abscessus_ATCC_1997      IPDGISGVEAATIPAAALTVR-LSFDWAQLKPGDKVLIHAASGGVGLAAI
MSMEG_0408|M.smegmatis_MC2_155      IPDGIGAVEAATIPAAALTVR-LAFDWAQLKPGDKVLIHAASGGVGLAAI
Mvan_1003|M.vanbaalenii_PYR-1       VPEGISAVAAATTPAAVLTAG-LAFDWAALRAGDRVLIHAASGGVGLAAV
TH_2454|M.thermoresistible__bu      WPDTDPPAAVVLVGGDARTRAFVTRDLDEARVAHRSYADPAALPPDLTAG
                                     *       ..       :           :       .  :     :: 

Mb2074c|M.bovis_AF2122/97           QLARHLG-----------------------LEVFATASKGKWDTLRAMGF
Rv2048c|M.tuberculosis_H37Rv        QLARHLG-----------------------LEVFATASKGKWDTLRAMGF
MUL_2266|M.ulcerans_Agy99           QLARHWG-----------------------LEVFATASKGKWDTLRAMGF
MAV_2450|M.avium_104                QLARHLG-----------------------LEVFATASRGKWDTLRDMGF
MLBr_00135|M.leprae_Br4923          QFARHWG-----------------------VEIFVTASRGKWDTLRDMGF
MMAR_3798|M.marinum_M               TLSNHPSRMFSPTTPFAAGRTPNAVDQDSFYEELAQHGVRYDGAFRALHS
Mflv_0405|M.gilvum_PYR-GCK          QMAQQCG-----------------------AEVYATASTFKRATLRKLGV
MAB_0939|M.abscessus_ATCC_1997      QMAQQFG-----------------------AEVFATASTFKRATLRKLGV
MSMEG_0408|M.smegmatis_MC2_155      QMAQQSG-----------------------AEVFATASTFKRSTLRRLGV
Mvan_1003|M.vanbaalenii_PYR-1       QLARQRG-----------------------ATVFATASGYKRPMLRAMGV
TH_2454|M.thermoresistible__bu      TVVLVLP------------------------RTAARPAASAQLVLHTLQR
                                     .                                .  .      :: :  

Mb2074c|M.bovis_AF2122/97           DDDHISDSRSLEFEDKFRAATGGRG-------FDVVLDSLAGE-FVDAS-
Rv2048c|M.tuberculosis_H37Rv        DDDHISDSRSLEFEDKFRAATGGRG-------FDVVLDSLAGE-FVDAS-
MUL_2266|M.ulcerans_Agy99           DEDHIGDSRSLEFEDKFRAATGGRG-------MDVVLDSLAGE-FVDAS-
MAV_2450|M.avium_104                DDDHLGDSRGLDFEDKFRAVTGGAG-------MDIVLDSLSGD-SVDAS-
MLBr_00135|M.leprae_Br4923          DDDHIGDSRTLEFEEKFLAVTDGRG-------VDVVLDSLAGD-FVDAS-
MMAR_3798|M.marinum_M               LENNPSDTDTTCAEVALPADTDVDGYGIHPALLDAALQPLAAA-FTDTDT
Mflv_0405|M.gilvum_PYR-GCK          K--HVYDSRTTDFAEQILADTDGAG-------VDVVLNSLTSEGFIEAT-
MAB_0939|M.abscessus_ATCC_1997      K--YVYDSRTTDFADQILADTDGAG-------VDVVLNSLTSEGFIEAT-
MSMEG_0408|M.smegmatis_MC2_155      K--YVYDSRTTDFADQILADTNGAG-------VDVVLNSLTSAGFVEAT-
Mvan_1003|M.vanbaalenii_PYR-1       D--HVYDSRTTDFADQILADTDGAG-------VDVVLNSLTNDGFVAAT-
TH_2454|M.thermoresistible__bu      LSATNSGARLWVLTRGVHEGTDPGHG---------PLWGLARVAAAEHP-
                                          .:        .   *.              *  *:         

Mb2074c|M.bovis_AF2122/97           ----------------------------LRLVAPGGVFLEMGKTDIRDPG
Rv2048c|M.tuberculosis_H37Rv        ----------------------------LRLVAPGGVFLEMGKTDIRDPG
MUL_2266|M.ulcerans_Agy99           ----------------------------LRLVAPGGVFLEMGKTDIREAA
MAV_2450|M.avium_104                ----------------------------LRLVAPGGIFLEMGKTDIRDPE
MLBr_00135|M.leprae_Br4923          ----------------------------LRLLVRGGRFLEMGKTDIRDAQ
MMAR_3798|M.marinum_M               DAPSAATPRMPFVITGVNLHATGARRLLVQLTATDADTFSLHATDPAGAT
Mflv_0405|M.gilvum_PYR-GCK          ----------------------------LRATAQHGRFAEIAKRDIWTVE
MAB_0939|M.abscessus_ATCC_1997      ----------------------------LRATAKNGRFAEIAKRDIWTTE
MSMEG_0408|M.smegmatis_MC2_155      ----------------------------LKATAQGGRFAEIAKRDIWSHE
Mvan_1003|M.vanbaalenii_PYR-1       ----------------------------VRATARNGRFAEIAKRDIWSPE
TH_2454|M.thermoresistible__bu      --------------------------------QLWGGLLDIGEDRLPVRA
                                                                       .   .:         

Mb2074c|M.bovis_AF2122/97           VIAQQYPGVR-------YRAFDLFEAGPDRIAQILAELATLFGDGVLRPL
Rv2048c|M.tuberculosis_H37Rv        VIAQQYPGVR-------YRAFDLFEPGPDRIAQILAELATLFGDGVLRPL
MUL_2266|M.ulcerans_Agy99           VVAQQHTGVR-------YRAFDLFEAGPDHIAQILAELAALFSEDVLRPL
MAV_2450|M.avium_104                VVAAEHPGVR-------YRAFDLFEAGPDRIARLLDELAAMFGEDVLRPL
MLBr_00135|M.leprae_Br4923          EIAANYPGVQ-------YRAFDLSEAGPVRMQEMLCEVRELFDTQVLHRL
MMAR_3798|M.marinum_M               VITINAVTLRALTDIGSLRTSGISRRGLLELAWPALPPDTFSTAAVLPPL
Mflv_0405|M.gilvum_PYR-GCK          QMAAARPDLAY----EIVALDTVMFTEPDRIRDLLTEVSAGLRDGAWTPL
MAB_0939|M.abscessus_ATCC_1997      QMAQSRPDIAY----EIVALDTVMFQEPDRIRVLLTEVSEGLAKGEWTPL
MSMEG_0408|M.smegmatis_MC2_155      QMAEARPDIAY----EIVALDTVMFTEPDRIRDLLTEVSDGMARGEWTPL
Mvan_1003|M.vanbaalenii_PYR-1       QMAAARPDIDY----EVLALDAVMQQDPDRIQLLLADLADSLARGETAPL
TH_2454|M.thermoresistible__bu      LTALTG-------------HGVVVVRDGVAHTARLAPAGPGARDSAGEGL
                                      :                   :                          *

Mb2074c|M.bovis_AF2122/97           PVTT---------------------------------FDVRRAP------
Rv2048c|M.tuberculosis_H37Rv        PVTT---------------------------------FDVRCAP------
MUL_2266|M.ulcerans_Agy99           PVTT---------------------------------FDVRRAP------
MAV_2450|M.avium_104                PVTR---------------------------------FDVRRAP------
MLBr_00135|M.leprae_Br4923          PVTS---------------------------------WDVRCAP------
MMAR_3798|M.marinum_M               ALVSSHSDDLAHALGQSSQCTVYTDLAAVQPCPPLVLWDLTAGPDPTPTP
Mflv_0405|M.gilvum_PYR-GCK          PAEV-------------------------YPLTEAR--------------
MAB_0939|M.abscessus_ATCC_1997      PAEI-------------------------YPLTEAR--------------
MSMEG_0408|M.smegmatis_MC2_155      PAEI-------------------------YPITEAR--------------
Mvan_1003|M.vanbaalenii_PYR-1       PFEA-------------------------YPLAEAT--------------
TH_2454|M.thermoresistible__bu      RCSP----------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           --------------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        --------------------------------------------------
MUL_2266|M.ulcerans_Agy99           --------------------------------------------------
MAV_2450|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MMAR_3798|M.marinum_M               EDGDTEDPLQRVHTLTRHTLAGLQNWLNRSDTTGTHLVILTRRAVTTVPD
Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           -----------AALRYLSQARHTGKVVMLMP-------------------
Rv2048c|M.tuberculosis_H37Rv        -----------AALRYLSQARHTGKVVMLMP-------------------
MUL_2266|M.ulcerans_Agy99           -----------AALRYLSQARHVGKVVLTMP-------------------
MAV_2450|M.avium_104                -----------AALRYLSQARHVGKVVMTMP-------------------
MLBr_00135|M.leprae_Br4923          -----------AAFRFMSQARHIGKVVLTMPS------------------
MMAR_3798|M.marinum_M               DRSPDPAHAATWAFAHSAQNEHPNRITLIDIDNTPATSQTLTNILTTLTN
Mflv_0405|M.gilvum_PYR-GCK          -----------AAFRRMQQARHIGKIVVQIPN------------------
MAB_0939|M.abscessus_ATCC_1997      -----------TAFRRMQQARHIGKIVCQMPN------------------
MSMEG_0408|M.smegmatis_MC2_155      -----------SAFRRMQQARHIGKIVLQVPK------------------
Mvan_1003|M.vanbaalenii_PYR-1       -----------TAFRRMQQARHTGKIILQMPK------------------
TH_2454|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mb2074c|M.bovis_AF2122/97           ------------------------------------GSWAAGTVLITGGT
Rv2048c|M.tuberculosis_H37Rv        ------------------------------------GSWAAGTVLITGGT
MUL_2266|M.ulcerans_Agy99           ------------------------------------DAWAAGTVLITGGT
MAV_2450|M.avium_104                ------------------------------------DAWTAGTVLITGAT
MLBr_00135|M.leprae_Br4923          ---------------------------------ALADGLAEGTVLITGAS
MMAR_3798|M.marinum_M               PTSAPTEPQLALRHGTPHTPRLTPTTTETTTTSPPLEFDPAGTVLITGGT
Mflv_0405|M.gilvum_PYR-GCK          ----------------------------------PLQPQPDRSYLITGGL
MAB_0939|M.abscessus_ATCC_1997      ----------------------------------PLAPRPDRTYLITGGL
MSMEG_0408|M.smegmatis_MC2_155      ----------------------------------PLQPQQDRSYLITGGL
Mvan_1003|M.vanbaalenii_PYR-1       ----------------------------------PLQPHGDRSYLITGGL
TH_2454|M.thermoresistible__bu      ----------------------------------------GGTYLITGGT
                                                                              : ****. 

Mb2074c|M.bovis_AF2122/97           GMAGSAVARHVVARHGVRNLVLVSRRGPDA---------PGAAELVAELA
Rv2048c|M.tuberculosis_H37Rv        GMAGSAVARHVVARHGVRNLVLVSRRGPDA---------PGAAELVAELA
MUL_2266|M.ulcerans_Agy99           GMAGSALARHVVAHHGVRQLVLVSRRGPDA---------PGAAELAEELS
MAV_2450|M.avium_104                GMAGSAVARHVVTRHGARNLVLVSRRGLDA---------PDAAELVAELT
MLBr_00135|M.leprae_Br4923          GAIGGVLARHMVSAYGVRHLVLASRRGDRA---------EGAVELAAELV
MMAR_3798|M.marinum_M               GMLGAVFAEHMIARYGARHLLLVSRSGPDA---------PGADDLYQRLT
Mflv_0405|M.gilvum_PYR-GCK          GAIG-LHTAGYLAQLGAGDIVLTSRRAPDA---------AAQQAIADIAD
MAB_0939|M.abscessus_ATCC_1997      GAIG-LHTAAYLAQLGAGDIVLTSRRAPDT---------DAQRVIGEITE
MSMEG_0408|M.smegmatis_MC2_155      GAIG-LHTAAYLAQLGAGDIVLTSRRDPDE---------SAQRAIDEITE
Mvan_1003|M.vanbaalenii_PYR-1       GALG-LHAAAYLAQLGAGDIVLTGRRMPDA---------ATERAISEIAE
TH_2454|M.thermoresistible__bu      GALG-LRLAHRLADLGARRLVLVSRSGMPARDSWGRAGDSDTVAAITALE
                                    *  *       ::  *.  ::*..*                         

Mb2074c|M.bovis_AF2122/97           AAGAQVQVVACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMS
Rv2048c|M.tuberculosis_H37Rv        AAGAQVQVVACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMS
MUL_2266|M.ulcerans_Agy99           AFGAQVQVVACDAADRAALAKLIADIPMQHP-LSAVIHTAGALDDAVVTS
MAV_2450|M.avium_104                AAGAHAEVVACDAADREALAKVIADIPMQHP-LTGVIHAAGVLDDAVVTS
MLBr_00135|M.leprae_Br4923          GAGAKIQVVACDVADNDAVRGLFAQLSREFPPVRGVIHAAGVLDDGAITS
MMAR_3798|M.marinum_M               QLGAQITITACDASDPTALAAVLANIPTEHP-LRAVIHTAAVIDDAVVTE
Mflv_0405|M.gilvum_PYR-GCK          RTKARLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQ
MAB_0939|M.abscessus_ATCC_1997      RSKTRIHVFTADVGAESEVAGLLERIRAELPPLAGVAHLAGVLDDALLGQ
MSMEG_0408|M.smegmatis_MC2_155      RHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSA
Mvan_1003|M.vanbaalenii_PYR-1       RYHCRIHTFAADVGDESAVRDLLERIRTELPPLAGVAHLAGVLDDALLPQ
TH_2454|M.thermoresistible__bu      ERGVSVRVAALDIG-APGAAARLREVLADLPDVRGVIHAAGVEAGALLTN
                                             : * .        :  :  : * : .: * *..  .. :  

Mb2074c|M.bovis_AF2122/97           LTPDRVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANY
Rv2048c|M.tuberculosis_H37Rv        LTPDRVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANY
MUL_2266|M.ulcerans_Agy99           LTPERIETVLRAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQGNY
MAV_2450|M.avium_104                LTPQRIDTVLRAKVDAAWNLHELTRDLDVGAFVMFSSIAGLAGASGQGNY
MLBr_00135|M.leprae_Br4923          LTPDRVDTVLRAKVDAAWNLHEATRDLDLLMFVLCSSIAATVGSPGQGNY
MMAR_3798|M.marinum_M               LTVEQLDMVLAAKADTAWHLHRLTADINLDVFVVFSAAAAVLGAPGLANY
Mflv_0405|M.gilvum_PYR-GCK          QSVERFRTALAPKAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSPGQSNY
MAB_0939|M.abscessus_ATCC_1997      QSVERFRTTLAPKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGSPGQSNY
MSMEG_0408|M.smegmatis_MC2_155      QNPERFRTTLAPKAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANY
Mvan_1003|M.vanbaalenii_PYR-1       QSPERFRTTLAPKAFGAWHLHRLTRDTELEFFIVYSSGSSVLGSPGQANY
TH_2454|M.thermoresistible__bu      TTAEDIEATMRPKVDGVLALHEVFPPGRLDWLVLFSSCGYLGGFPGQGAY
                                     . : .  .: .*.  .  *..      :  ::: *: .   * .* . *

Mb2074c|M.bovis_AF2122/97           AAANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTSGLATVDFKRFARD
Rv2048c|M.tuberculosis_H37Rv        AAANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTGGLATVDFKRFARD
MUL_2266|M.ulcerans_Agy99           AAANSFLDGLAVHRQAHGLPAISLGWGLWDQASNMTGGLAAVDFKRFARD
MAV_2450|M.avium_104                AAGNSFLDGLAAHRRAHGLPAISLGWGLWDQASAMTGGLGAADLARFGRD
MLBr_00135|M.leprae_Br4923          SAANAFLDGLAAYRQAAGLAGTSLAWGLWEQPGGMNAHLSSRDLARISRS
MMAR_3798|M.marinum_M               AAANAFLDALAHHRHHHGLPATSLAWGYWQTPG-IAAHLDTVSQARFTRN
Mflv_0405|M.gilvum_PYR-GCK          ATANAFLDGLVAQRRAQGLPATGVNFGPWARGGMASSEAAAANISAQGLI
MAB_0939|M.abscessus_ATCC_1997      ATANALLDGLIAQRRAQGLPATGINFGPWGQGGMASSEAATANISAQGLI
MSMEG_0408|M.smegmatis_MC2_155      ATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANITAQGLI
Mvan_1003|M.vanbaalenii_PYR-1       ATANAVLDGLVAHRKARGLPATGVNWGPWAQGGMATSDAARANLGAQGLI
TH_2454|M.thermoresistible__bu      ACGNAYLDAFARYRRASGDATTSVAWTAWRGLG--MGSASDFVAAQLDAL
                                    : .*: **.:   *:  *    .: :  *   .   .             

Mb2074c|M.bovis_AF2122/97           GIVAMSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMFVD
Rv2048c|M.tuberculosis_H37Rv        GIVAMSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMFVD
MUL_2266|M.ulcerans_Agy99           GIVAMSSDEALGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMFVD
MAV_2450|M.avium_104                GIVAMSSQEALELMDTALIVDEPFLLPAHIDLAALRVKFDGGTLPPMFVD
MLBr_00135|M.leprae_Br4923          GLAPMNPAQALELFDAALVIDHPFMVTALLDRAALDAQAQAGALPPLFSR
MMAR_3798|M.marinum_M               HLIPITTEHGLALFDAALACQQPNLVPAPLNTHTLARQARQGVLPAILSS
Mflv_0405|M.gilvum_PYR-GCK          PLEPSAALTAMAEVVANGTAQATVLKANWQRAAKVLGSSRPPILDLVLPS
MAB_0939|M.abscessus_ATCC_1997      PLDPSAALAALAEVVANGTGQATILKANWQRAAKVLGSSRPPILDLVLPS
MSMEG_0408|M.smegmatis_MC2_155      PLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLVLPS
Mvan_1003|M.vanbaalenii_PYR-1       PLEPTAALNALGEIVAHGIASAVVLKANWQRAAKLLGATRPPILDHVLPS
TH_2454|M.thermoresistible__bu      GMGTVDVDDAMRALDAAIRDGDPNVVVLPLSPAAAAVPMFADVAPADPDA
                                     : .     .:  . :        :                         

Mb2074c|M.bovis_AF2122/97           LINAPTRRQVDDSLAAAKSKSALAHRLHGLPEDEQHAVLLDLVRSHIATV
Rv2048c|M.tuberculosis_H37Rv        LINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAVLLDLVRSHIATV
MUL_2266|M.ulcerans_Agy99           LINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIATV
MAV_2450|M.avium_104                LINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQQAVLLDLVRSNIATV
MLBr_00135|M.leprae_Br4923          LVRRSRRRQIEDPGDATQSKLALVQRLQGLAANRQLELLVGVVCLQAAAV
MMAR_3798|M.marinum_M               LITTRRHATIG-------SVETLTAQLATQTPEQQLATLTRLVTTATAAV
Mflv_0405|M.gilvum_PYR-GCK          AVGEIT------------GDSELLKQLQEIPVPQRAGFVTEFLQKEVQNF
MAB_0939|M.abscessus_ATCC_1997      AVGEVT------------GDSELLKQLMEIPVPQRAGFVTEFLQREVQNF
MSMEG_0408|M.smegmatis_MC2_155      AAGEAT------------GDSELLKQLMEIPIPQRAGFVTEFLQREVQNF
Mvan_1003|M.vanbaalenii_PYR-1       AVAAGP------------GDSALLKQLQDVPEAQRGSFVTEHLQRELQQI
TH_2454|M.thermoresistible__bu      DAPGGE------------VPDGLSDGFPADGFPDDGDLAEWVHRRVIAAV
                                                          *   :                      .

Mb2074c|M.bovis_AF2122/97           LGSA--SPEAIDPDRAFQDLGFDSLTAVEMRNRLKSATG--LSLSPTLIF
Rv2048c|M.tuberculosis_H37Rv        LGSA--SPEAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIF
MUL_2266|M.ulcerans_Agy99           LGNS--SPDAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIF
MAV_2450|M.avium_104                LGSS--SPEAIHPDRAFQELGFDSLTAVEMRNRLKAATG--LALSPTLIF
MLBr_00135|M.leprae_Br4923          LGRP--SPEDIDPNTKFQDLGFDSLTAVELRNRLKSATG--LTLPPTVIF
MMAR_3798|M.marinum_M               LAHP--DPATLEPDLPFKDLGIDSLSALELRNTLTRDTG--ASLPATLVF
Mflv_0405|M.gilvum_PYR-GCK          LRLA--QPPAATS--RFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVF
MAB_0939|M.abscessus_ATCC_1997      LRLA--QPPAATS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVF
MSMEG_0408|M.smegmatis_MC2_155      LRLA--SPPAASS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVF
Mvan_1003|M.vanbaalenii_PYR-1       LGLA--QPPAATG--RFLELGMDSLMAVELRNRLVGQFGSGFTITATAVF
TH_2454|M.thermoresistible__bu      AGELGLAETDVDPRLPLVEIGVDSIMTVALRRQLERQTG--LTLPPTLLW
                                                    : ::* **: :: :*. *    *   :: .* ::

Mb2074c|M.bovis_AF2122/97           DYPNSAALAGYMRRELLGSSPQ-DTSAVAAGEAELQRIVASIPVKRLRQA
Rv2048c|M.tuberculosis_H37Rv        DYPNSAALAGYMRRELLGSSPQ-DTSAVAAGEAELQRIVASIPVKRLRQA
MUL_2266|M.ulcerans_Agy99           DYPNSAALAGYMHRELVGASPQSDTTAEAPGEAELQRVVASIPVKRLRQA
MAV_2450|M.avium_104                DYPNSAALAGYMYRELVGTSEQ-PTAAAAPGEAEIQRVVGSIPVKRLRQA
MLBr_00135|M.leprae_Br4923          DHPTPTAVAEYVAQQMLKSRPA------ESGDETSQAVEPKVEEVSVHA-
MMAR_3798|M.marinum_M               DHPTPSAIAQYLNIQLSGSSTT--SRVQDPEEIEMQNLIAKIPAKQLIKS
Mflv_0405|M.gilvum_PYR-GCK          DYPTIGGLAEYLVAQLPDAETPQAAP-------QSESEPGPDVTE-----
MAB_0939|M.abscessus_ATCC_1997      DYPTIGGLAEYLVGQLPDADAESAEAPPAVESAEAESGAGPAAASDAVSE
MSMEG_0408|M.smegmatis_MC2_155      DYPTIGGLAEYLVGQLPDAEAPETA-------------------------
Mvan_1003|M.vanbaalenii_PYR-1       DYPTIGALAEYLAAQTPESTEEGTEMKTADPDGQPATVGHADVVLQTS--
TH_2454|M.thermoresistible__bu      EHPTAGAVSDRIVEMLRARG------------------------------
                                    ::*.  .::  :                                      

Mb2074c|M.bovis_AF2122/97           GVLDLLLALANETETSGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE-
Rv2048c|M.tuberculosis_H37Rv        GVLDLLLALANETETSGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE-
MUL_2266|M.ulcerans_Agy99           GVLELLLALANETGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE-
MAV_2450|M.avium_104                GVLELLLALANESTGTAQSATPAVTTEKDIADMDLDDLVNAALLDDDDE
MLBr_00135|M.leprae_Br4923          -------------------------------------------------
MMAR_3798|M.marinum_M               GVLNILREIADIEHSSSANEKQDNVATMNLDELLIALGDHKGENKNDH-
Mflv_0405|M.gilvum_PYR-GCK          -------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      LKE----------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      -------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       -------------------------------------------------
TH_2454|M.thermoresistible__bu      -------------------------------------------------