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M. avium 104 MAV_2450 (-)

annotation: erythronolide synthase, modules 3 and 4
coordinates: 2474065 - 2486580
length: 4171

VMVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGVDSPEALWQMVAEGRDVISE
FPTDRGWDLAALYDPDPDARHKCYVNTGGFVDNVADFDPAFFGIAPSEALAMDPQHRMLLELSWEALERA
GIDPSGLRGSATGVFAGLIVQGYGMLAEEIEGYRLTGMTSSVASGRVSYVLGLEGPAVSVDTACSSSLVA
LHMAVQSLRSGECDLALAGGATVNATPTVFVEFSRHRGLAPDGRCKAYAGAADGVGWSEGGAMLVVERLS
DARRLGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIE
AQALLATYGQDRGQPLWLGSIKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDEPSPHVDWSAGAVS
LLTEAQPWPGERPRRAGVSSFGISGTNAHVIIEAVPAVEPAHADAPALPVLPWVVSAKSAAALRAQAARL
AEYVRAQGELDIADVGWTLAGRATFEHRAVVVGGDRDRLLAGLDELAADDPAASIIRGVATPAGKTVFVF
PGQGSQWLGMATELLDTAPVFAQHIQACEEAFAEFVDWSLIDALRGAPGAAGMDRVDVVQPALFAVMVSL
AELWKSVGVSPDAVIGHSQGEIAAAYVAGALSLRDAARVVTLRSKLLRSLAGPGGMLSIACSTERARELL
APYGNRVSIAAVNGRSAVVVSGEGAALDELAAFCADLALRTRRIDVDYASHSVEVEAIREDLAQALTGIE
PRSSRIAFFSTVTGNRLDTAGLDADYWYRNIRQTVQFDQTVRSAAEHGYRTFIESSPHPALVAGIEDTVN
DSLPGDTEAIVIPTLGRDDGGLERFLTSAATAFVAGVNVAWRGVLDGAGFVELPTYAFDRRRFWLSGEGA
AADASGLGLGTSEHPLLSAVVELPASGGVVLTGRLSPSLQGWLTDHAVSGTVVFPGAGFVELAIRAGDEV
GCSTVEELTLQAPLMLPAKDSGIGSVAVQVLVGEADESGRRDVSIFSRPDSDSPWVCHAQGTLSTGSIEP
GADLAAWPPAGATKVDIADGYQRLAARGYGYGPAFQGLTAAWVRGDEVFAEVRLPDAAGGVTGFGVHPAL
LDAAMHALIVGHQIAGDTDEVALPFAWQGVSLHAAGASAVRARLAPAQAPGTAASRAVSLELADGLGLPV
LSVRAMVARSVSERQLRAAVSAAGPDRLFEVAWAPVTVPAAHGEPPVHQVFESLAAEGDPVGESYRRTHE
ALAAVQSWLTEHDSGVLVVVTRGAMALAGEDVTDLSGAAVWGLVRSAQTEHPGRIVLIDSDAALDDSALT
AALATGEPQVLLRDGTVYTARVHGSRAVDGIMTPPEDRPWRLGISSAGTFENLQLEPVPNPDAALQPGQV
RVALRAIATNFRDVMITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVYGFFPDGSGTLVPGDVRLL
QHKPTHWSYPEAAGISAVFTTAYMAFIHLADVKPGQRVLVHAAAGGVGMAAVQLARHLGLEVFATASRGK
WDTLRAMGFDDDHIGDSRTLEFEDKFRSATGGAGMDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRD
PGVVAREYPGVRYRAFDLFEPGRPRMRQWMVELAGLFDAGVLNPLPVTTFDIRRGRAALRYLSQARHIGK
VVMTVPGALSAGTVLITGGTGMAGSTLARHLVTGHGVRDLALLSRTGPDAPGAAEFVAELEAAGARVQVI
ACDAADRAALAGVIAGISAERPLSGVIHAAGVLDDAMITSLTPERIDAVLRAKVDAAWNLHELTRDMNLS
AFVMFSSMAGLVGSSGQGNYAAANSFLDALAAHRRAHGLPAISLAWGLWDQASAMTGGLDAADLARLGRD
GILALSSDEAMELFDTALIVDEPFLAPARIDLGALRAHAVAVPPMFADLVNAPTRRRVDDSLAAAKSKSA
LAHRLDGLPEAEQHAVLLELVRSHIATVLGSPTAEAIDPDKAFQELGFDSLTAVEMRNRLKTATGLALSP
TLIFDYPTPNALAGYIRTELAGAPQETTHAPVVRATDDDPIAIVGMSCRFPGGVDSPEALWQMVAEGRDV
LSEFPTDRGWDLAGVYNPDPDVPGTCYTRTGGFVDNVADFDPAFFGIAPSEALAMDPQQRMFLELSWEAL
ERAGIDPVKLRGSATGMFAGVYTQGYGMGAAPIAEGFRLTGQSSSVASGRVSYVLGLEGPAVSVDTACSS
SLVALHMAVQSLRSGECDLALAGGVTVNATPDIFVEFSRMRGLSVDGRCKAYAGAADGTGFSEGGGMLVV
ERLSDARRLGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLG
DPIEAQALLATYGQDRGQPLWLGSIKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDEPSPHVDWSA
GAVSLLTEAQPWPGERPRRAGVSSFGISGTNAHVIIEAVPAVEPAHADAPALPVLPWVVSAKSAAALRAQ
AARLAEYVRAQGELDIADVGWTLAGRATFEHRAVVVGGDRDRLLAGLDELAADDPAASIIRGVATPAGKT
VFVFPGQGSQTLGMGRQLHAGYPVFAEAFDAVVAELDRHLLRPLRDVIWGDDENVLNSTEFAQPALFAVE
VALFRLLESWGVRPDFVMGHSIGELSAAHVAGVLSLQNAAVLVAARGRFMQALPEGGAMIAVQATEAQVR
PLLGPDVGIAAVNGPAAVVISGDHDAAVAIAERLRAEGHRVHRLSVSHAFHSPLMEPMIDEFGTVAAGLA
IDKPVIPIISNLTGQPAADDFGSPEYWKCHVRDAVRFADSVRFAQSAGATRFLEVGPSSGLTAAIEETLA
DAPVVTVSALRKDRPEPVALVNAVAQGWVCGMDVDWRGALGTGHLVDLPTYAFDRRRFWLSGDGAASDAA
GLGLAAGDHALLGAVVELPASGGVLLTGRLSPASQGWLADHAVGGVVLFPGAGFVELAIRAGDEVGCGII
DELNLAAPLVLPAGGSVAIQVVVDGPDDSGARAVSVFSRADAGAGWLLHAEGVLRAGSAQPATDLSAWPP
VGAVPVDLGDGYEQLAERGYRYGPAFRGLTSMWRRGDEIFAEVNLPTDAGVSTTGFGVHPVMLDAALHAV
MLASDGDDLPAGSMLVPFSWQRVSLHAAGAAAVRARIVPVSPSAVSIELADGLGLPVLSVASMVARPVTD
QQLLAAVSNSGPDRLFELIWSAQPSTAVQPVSLLNWGATELDATDTDSDSGRFAVLFESAPVAGDVVTEV
YAATRAVLPVLQSWLARDGAGTLVVSTRGAMTLPGEDVTDLAGAAVWGLVRSAQTEHPGRIVLVDTDAPL
DADAVAAVLAVGEPQTLLRNGTVYTARVLGSRAVGALLVPPEDGPWRLGMSSYGTIENLRLEPIPDADAP
LGPGQVRVATSALAANFRDVMIALGLYPDPDAVMGIEASGVVIETASQDGRVAVGDRVMGLFPDGTGTVA
TTDQRLLVKVPAGWSHTAAATASVVFATAYYALVDLADARPGQRVLVHAAAGGVGMAAVQLARHLGLEVF
ATASRGKWDTLRDMGFDDDHLGDSRGLDFEDKFRAVTGGAGMDIVLDSLSGDSVDASLRLVAPGGIFLEM
GKTDIRDPEVVAAEHPGVRYRAFDLFEAGPDRIARLLDELAAMFGEDVLRPLPVTRFDVRRAPAALRYLS
QARHVGKVVMTMPDAWTAGTVLITGATGMAGSAVARHVVTRHGARNLVLVSRRGLDAPDAAELVAELTAA
GAHAEVVACDAADREALAKVIADIPMQHPLTGVIHAAGVLDDAVVTSLTPQRIDTVLRAKVDAAWNLHEL
TRDLDVGAFVMFSSIAGLAGASGQGNYAAGNSFLDGLAAHRRAHGLPAISLGWGLWDQASAMTGGLGAAD
LARFGRDGIVAMSSQEALELMDTALIVDEPFLLPAHIDLAALRVKFDGGTLPPMFVDLINAPTRRQVDDS
LAAAKSKSALLQRLEGLPEDEQQAVLLDLVRSNIATVLGSSSPEAIHPDRAFQELGFDSLTAVEMRNRLK
AATGLALSPTLIFDYPNSAALAGYMYRELVGTSEQPTAAAAPGEAEIQRVVGSIPVKRLRQAGVLELLLA
LANESTGTAQSATPAVTTEKDIADMDLDDLVNAALLDDDDE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_2450--100% (4171)erythronolide synthase, modules 3 and 4
M. avium 104MAV_3109-0.062.01% (2077) RifB protein
M. avium 104MAV_3108-0.058.79% (2133) erythronolide synthase, modules 3 and 4

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2074cpks120.080.68% (4177) polyketide synthase pks12
M. gilvum PYR-GCKMflv_0405-0.036.85% (2567) beta-ketoacyl synthase
M. tuberculosis H37RvRv2048cpks120.080.90% (4177) polyketide synthase pks12
M. leprae Br4923MLBr_00135-0.059.43% (2053) putative polyketide synthase
M. abscessus ATCC 19977MAB_0939-0.036.16% (2597) polyketide synthase
M. marinum MMMAR_3025pks120.080.27% (4206) polyketide synthase, Pks12
M. smegmatis MC2 155MSMEG_0408-0.036.43% (2539) type I modular polyketide synthase
M. thermoresistible (build 8)TH_4621-0.034.17% (1876) PUTATIVE mycocerosic acid synthase
M. ulcerans Agy99MUL_2266pks120.079.86% (4210) polyketide synthase, Pks12
M. vanbaalenii PYR-1Mvan_1003-0.037.33% (2550) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0405|M.gilvum_PYR-GCK          -----------------------MGSAAHQGE-SAHRFAIVGYAGRFPG-
MAB_0939|M.abscessus_ATCC_1997      -----------------------MDSAENPIE-STPRFAIIGYAARFPG-
MSMEG_0408|M.smegmatis_MC2_155      -----------------------MVSAEHPIE-PTPSFAIIGYAARFPG-
Mvan_1003|M.vanbaalenii_PYR-1       ---------MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPG-
MMAR_3025|M.marinum_M               -MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG
MUL_2266|M.ulcerans_Agy99           -MVDQLQHATEALRKALVQVERLKRTKRALLERSSEPIAIVGMSCRFPGG
Mb2074c|M.bovis_AF2122/97           -MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG
Rv2048c|M.tuberculosis_H37Rv        -MVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG
MAV_2450|M.avium_104                MMVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ARDAESFWELLADGRDAISEVPEDR-WDVEAFFDPDPSTPGKVVTRRAGF
MAB_0939|M.abscessus_ATCC_1997      AADAEEFWDVLREGRDAISEVPADR-WDAEEFFDPEPGAPGKVVTRRAGF
MSMEG_0408|M.smegmatis_MC2_155      AASAEEYWALLRDGREAISDVPKDR-WDIEEFFDPDPSTPGKVVTRRAGF
Mvan_1003|M.vanbaalenii_PYR-1       AADADEFWDVLRGGRDAISEVPQDR-WDADEFFDADPEAAGKMVTRRAGF
MMAR_3025|M.marinum_M               VDSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHKSYASTGGF
MUL_2266|M.ulcerans_Agy99           VDSPEGLWQMVAEGRDVMSDFPTDRGWDLADLFDPDPDTPHKSYASTGGF
Mb2074c|M.bovis_AF2122/97           VDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGF
Rv2048c|M.tuberculosis_H37Rv        VDSPEGLWQMVADARDVMSEFPTDRGWDLAGLFDPDPDVRHKSYARTGGF
MAV_2450|M.avium_104                VDSPEALWQMVAEGRDVISEFPTDRGWDLAALYDPDPDARHKCYVNTGGF
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VDDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANT
MAB_0939|M.abscessus_ATCC_1997      VEDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTDLAET
MSMEG_0408|M.smegmatis_MC2_155      VDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANS
Mvan_1003|M.vanbaalenii_PYR-1       VEDVAGFDAPFFGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGT
MMAR_3025|M.marinum_M               VDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGS
MUL_2266|M.ulcerans_Agy99           VDGVADFDPGFFGIAPSEALAMDPQHRMLLELSWEALERSGIDPTGLRGS
Mb2074c|M.bovis_AF2122/97           VDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGS
Rv2048c|M.tuberculosis_H37Rv        VDGVADFDPAFFGISPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGS
MAV_2450|M.avium_104                VDNVADFDPAFFGIAPSEALAMDPQHRMLLELSWEALERAGIDPSGLRGS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          NTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQ
MAB_0939|M.abscessus_ATCC_1997      NSGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQ
MSMEG_0408|M.smegmatis_MC2_155      NTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQ
Mvan_1003|M.vanbaalenii_PYR-1       RTGVFMGLSTHDYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQ
MMAR_3025|M.marinum_M               ATGVFAGLIVQGYG------MFAEEIEGYRLTGMTSSVASGRVAYVLGLE
MUL_2266|M.ulcerans_Agy99           ATGVFAGLIVQGYG------MFAEEIEGYRLTGMTSSVASGRVAYVLGLE
Mb2074c|M.bovis_AF2122/97           ATGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLE
Rv2048c|M.tuberculosis_H37Rv        ATGVFAGLIVGGYG------MLAEEIEGYRLTGMTSSVASGRVAYVLGLE
MAV_2450|M.avium_104                ATGVFAGLIVQGYG------MLAEEIEGYRLTGMTSSVASGRVSYVLGLE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GPAVAVDTACSSSLVAIHQACQALRLGECDLALAGGANVILTPATMITFS
MAB_0939|M.abscessus_ATCC_1997      GPSVAVDTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFS
MSMEG_0408|M.smegmatis_MC2_155      GPAVAVDTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFS
Mvan_1003|M.vanbaalenii_PYR-1       GPAVAVDTACSSSLVAVHQACQALRLAECDVALAGGVNVLLSPATMINFS
MMAR_3025|M.marinum_M               GPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFS
MUL_2266|M.ulcerans_Agy99           GPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFS
Mb2074c|M.bovis_AF2122/97           GPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFS
Rv2048c|M.tuberculosis_H37Rv        GPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPTVFVEFS
MAV_2450|M.avium_104                GPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVFVEFS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          NAHMLAPDGRCKTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIR
MAB_0939|M.abscessus_ATCC_1997      HAHMLAPDGKCKTFDAAADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIR
MSMEG_0408|M.smegmatis_MC2_155      NAHMLAPDGRCKTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIR
Mvan_1003|M.vanbaalenii_PYR-1       RARMLAPDGRCKTFDATADGYVRGEGCGVVVVKRLADAIRHGDRIRAVIR
MMAR_3025|M.marinum_M               RHRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDAQRLGHPVLALVR
MUL_2266|M.ulcerans_Agy99           RHRGLAPDGRSKAYAGAADGVGWSEGGAMLVVERLSDAQRLGHPVLALVR
Mb2074c|M.bovis_AF2122/97           RHRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVV
Rv2048c|M.tuberculosis_H37Rv        RHRGLAPDGRCKPYAGRADGVGWSEGGGMLVLQRLSDARRLGHPVLAVVV
MAV_2450|M.avium_104                RHRGLAPDGRCKAYAGAADGVGWSEGGAMLVVERLSDARRLGHPVLAVVR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GSAINQDGASGGLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTS
MAB_0939|M.abscessus_ATCC_1997      GSAINQDGASGGLTVPNGVAQQRVIADALKRAGVAPSEVGYLEAHGTGTS
MSMEG_0408|M.smegmatis_MC2_155      GSAINQDGASGGLTVPNGVAQQRVIADALKRAGLRPADVGYLEAHGTGTS
Mvan_1003|M.vanbaalenii_PYR-1       GSAVNQDGASGGLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTP
MMAR_3025|M.marinum_M               GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
MUL_2266|M.ulcerans_Agy99           GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
Mb2074c|M.bovis_AF2122/97           GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
Rv2048c|M.tuberculosis_H37Rv        GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
MAV_2450|M.avium_104                GSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTT
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LGDPIEAQAAGAALGPGREPQ----RPLLIGSAKTNIGHLEAAAGIAGVI
MAB_0939|M.abscessus_ATCC_1997      LGDPIEAQAAGAAYGIGRETN----DPLLIGSAKTNIGHLEAAAGIAGVI
MSMEG_0408|M.smegmatis_MC2_155      LGDPIEAQAAGEVLGAGRAPE----EPLLIGSAKTNIGHLEAAAGIAGVI
Mvan_1003|M.vanbaalenii_PYR-1       LGDPIEVQAAGAVLGVGREPD----RPLLIGSVKTNIGHLEAASGIAGLL
MMAR_3025|M.marinum_M               LGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVI
MUL_2266|M.ulcerans_Agy99           LGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVI
Mb2074c|M.bovis_AF2122/97           LGDPIEAQALLATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVI
Rv2048c|M.tuberculosis_H37Rv        LGDPIEAQALLATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVI
MAV_2450|M.avium_104                LGDPIEAQALLATYGQDRGQP------LWLGSIKSNMGHTQAAAGVAGVI
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          KVVLSLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPR
MAB_0939|M.abscessus_ATCC_1997      KVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGR---NGRPR
MSMEG_0408|M.smegmatis_MC2_155      KVVMALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQR---NGKPR
Mvan_1003|M.vanbaalenii_PYR-1       KVILSLEHQVLPKHLNFRSPSPHIPWNRLPVRIVDDPVPWTR---SGRSR
MMAR_3025|M.marinum_M               KMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVR
MUL_2266|M.ulcerans_Agy99           KMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVR
Mb2074c|M.bovis_AF2122/97           KMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTR
Rv2048c|M.tuberculosis_H37Rv        KMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP---AGARTR
MAV_2450|M.avium_104                KMVLAMRHELLPATLHVDEPSPHVDWSAGAVSLLTEAQPWP----GERPR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          IAGVSSFGFAGTNAHVILEEAPLAAEPAQES---VDDGRFTLLPLSARTP
MAB_0939|M.abscessus_ATCC_1997      IAGVSSFGFAGTNAHVILEEAPVVSRDAVEPPAPAGGRKFSILPLSARTP
MSMEG_0408|M.smegmatis_MC2_155      IAGVSSFGFAGTNAHVILEEAPAVGTPATTEP-VEDPRRYSVLPLSARTP
Mvan_1003|M.vanbaalenii_PYR-1       VAGISSFGFSGTNAHVLVEEAPRADRAGAAPQ-PAAPGGFGMLPLSARTP
MMAR_3025|M.marinum_M               RAGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVP----WVVSAKSG
MUL_2266|M.ulcerans_Agy99           RAGVSSFGISGTNAHVIVEAAPRVEVGGSSGGAVPVVP----WVVSAKSG
Mb2074c|M.bovis_AF2122/97           RAGVSSFGISGTNAHVIIEAVPVVPRR-EAGWAGPVVP----WVVSAKSE
Rv2048c|M.tuberculosis_H37Rv        RAGVSSFGISGTNAHVIIEAVPVVPRR-EAGWAGPVVP----WVVSAKSE
MAV_2450|M.avium_104                RAGVSSFGISGTNAHVIIEAVPAVEPAHADAPALPVLP----WVVSAKSA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AALMAVADRYRDWLVANPDATLADLCFTAGTARSHLEHRAALVVNTREAA
MAB_0939|M.abscessus_ATCC_1997      AALAQLADKYRAWLNAHPEAALADLCFTAGVGRAHLEHRAALVVNTREAA
MSMEG_0408|M.smegmatis_MC2_155      EALVRLAGEYRDWLRAHPQARLADVSHTAGTARAHLEQRAALVVNSRESA
Mvan_1003|M.vanbaalenii_PYR-1       DALAATAHRLRTWLAANPDASWPDLCFTAAVGRSHLRHRAALVVDSRSSV
MMAR_3025|M.marinum_M               SALGAQAARLAAHVRSHDELDVADVGWSLAG-RSTFEHRAVVLGVDRDGL
MUL_2266|M.ulcerans_Agy99           SALGAQAARLAAHVRSHDELDVADVGWSLAG-RSTFEHRAVVLGADRDGL
Mb2074c|M.bovis_AF2122/97           SALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRL
Rv2048c|M.tuberculosis_H37Rv        SALRGQAARLAAYVRGDDGLDVADVGWSLAG-RSVFEHRAVVVGGDRDRL
MAV_2450|M.avium_104                AALRAQAARLAEYVRAQGELDIADVGWTLAG-RATFEHRAVVVGGDRDRL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LDLLGALADDRPA-PGLVRGESHDTPKTAWLFTGQGSQYPGMSRELFDTE
MAB_0939|M.abscessus_ATCC_1997      VELLSAVADDRPA-PGLGRGESHDTPKTAWLFTGQGSQYPGMARELFETE
MSMEG_0408|M.smegmatis_MC2_155      IELLGALADDRPA-PGLVRGESHEAPKTAWLFTGQGSQYPGMARELFDTE
Mvan_1003|M.vanbaalenii_PYR-1       EELLGALAEDRPG-PGLARGECGDPPKTAWLFTGQGSQYPGMGRELFDTE
MMAR_3025|M.marinum_M               LAGLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQWIGMGIELLDTA
MUL_2266|M.ulcerans_Agy99           LAGLDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQWIGMGIELLDTA
Mb2074c|M.bovis_AF2122/97           LAGLDELAGDQLG-GSVVRGTATAAGKTVFVFPGQGSQWLGMGIELLDTA
Rv2048c|M.tuberculosis_H37Rv        LAGLDELAGDQLG-GSVVRGTATAAGKTVFVFPGQGSQWLGMGIELLDTA
MAV_2450|M.avium_104                LAGLDELAADDPA-ASIIRGVATPAGKTVFVFPGQGSQWLGMATELLDTA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PLFAETLRECAAAVDGMLEKPLLDVIFDTDGVLDTDSNETLRHTSYAQPA
MAB_0939|M.abscessus_ATCC_1997      PVFADTLNRCAAAVADVLEKPLLDVIFDVD---GPEAEETLRQTSYAQPA
MSMEG_0408|M.smegmatis_MC2_155      PVFAETVRKCAEAVADILEKPLLDVIFDAD-ELDGDTESPLRHTTYAQPA
Mvan_1003|M.vanbaalenii_PYR-1       PVYREVMTRCAEAVADVLERPLLDVVFDAD------GGEALRHTSYAQPA
MMAR_3025|M.marinum_M               PVFARHIESCGQAFAEFVDWSLLDVLRGAA------GAPGLDRVDVVQPV
MUL_2266|M.ulcerans_Agy99           PVFARHIESCGQAFAEFVDWSLLDVLRGAA------GAPGLDRIDVVQPV
Mb2074c|M.bovis_AF2122/97           PAFAQQIDACAEAFAEFVDWSLVDVLRGAP------GAPGLDRVDVVQPV
Rv2048c|M.tuberculosis_H37Rv        PAFAQQIDACAEAFAEFVDWSLVDVLRGAP------GAPGLDRVDVVQPV
MAV_2450|M.avium_104                PVFAQHIQACEEAFAEFVDWSLIDALRGAP------GAAGMDRVDVVQPA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLSLRDGARLMAE
MAB_0939|M.abscessus_ATCC_1997      LFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLEDGARLIAE
MSMEG_0408|M.smegmatis_MC2_155      LFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAE
Mvan_1003|M.vanbaalenii_PYR-1       LYAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAE
MMAR_3025|M.marinum_M               LFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDAAKVVTL
MUL_2266|M.ulcerans_Agy99           LFAVMVSLAELWKSVGVRPDAVIGHSQGEIAAAYVAGALSLRDAAKVVTL
Mb2074c|M.bovis_AF2122/97           LFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTL
Rv2048c|M.tuberculosis_H37Rv        LFAVMVSLAELWKSVAVHPDAVIGHSQGEIAAAYVAGALSLRDAARVVTL
MAV_2450|M.avium_104                LFAVMVSLAELWKSVGVSPDAVIGHSQGEIAAAYVAGALSLRDAARVVTL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RGRLFGSLPSGGRMAAVFAAAERVEALTDEY-PALSVAAYNG-ANTVLSG
MAB_0939|M.abscessus_ATCC_1997      RGRLFSSLPAGGRMAAVFTDAERAERLTDEF-PSLSVAAYNG-ANTVLSG
MSMEG_0408|M.smegmatis_MC2_155      RGRLFGSLPAGGRMAAVFTAPERAERLTDEY-PSLSVAAYNG-ANTVLSG
Mvan_1003|M.vanbaalenii_PYR-1       RGRLFGSLPEGGRMAAVFAPADRVESCTVDS-PLLSVAAYNG-DNTVLSG
MMAR_3025|M.marinum_M               RSKLLVGLAGPGGMVSVACGEQQARELLEPFGDRVSIAAINGPSAVVVSG
MUL_2266|M.ulcerans_Agy99           RSKLLVGLAGPGGMVSVACGEQQARELLEPFGDRVSIAAINGPSAVVVSG
Mb2074c|M.bovis_AF2122/97           RSKLLAGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSG
Rv2048c|M.tuberculosis_H37Rv        RSKLLAGLAGPGGMVSIACGADQARDLLAPFGDRVSIAVVNGPSAVVVSG
MAV_2450|M.avium_104                RSKLLRSLAGPGGMLSIACSTERARELLAPYGNRVSIAAVNGRSAVVVSG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PATDLERAVAGLVADGVRCDWLETSHAFHSALLDPILDDFESYARGITFT
MAB_0939|M.abscessus_ATCC_1997      PAQDLEKAIAALVADGVRCDFLETSHAFHSALLDPILDEFEAYANQFNYK
MSMEG_0408|M.smegmatis_MC2_155      PAKDLESAVATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYR
Mvan_1003|M.vanbaalenii_PYR-1       PAGDLERAVAGFSAAGVRCDWLDTSHAFHSALLDPVLEEFESCADRFEFG
MMAR_3025|M.marinum_M               EVAALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQLTEVLAGIEPL
MUL_2266|M.ulcerans_Agy99           EVAALEELIAQCADRELRTRRIDVDYASHSVEVEAIEGQLTEVLAGIEPL
Mb2074c|M.bovis_AF2122/97           EVGALEELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAEALSGIEPR
Rv2048c|M.tuberculosis_H37Rv        EVGALEELIAVCSTKELRTRRIEVDYASHSVEVEAIRGPLAEALSGIEPR
MAV_2450|M.avium_104                EGAALDELAAFCADLALRTRRIDVDYASHSVEVEAIREDLAQALTGIEPR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          APQRILIDNRTGAALGRSVTLDAAYWRRHARQPVEFAKSVHTLADMNCKL
MAB_0939|M.abscessus_ATCC_1997      TPQRILIDNRTGTALGRSVKLDGAYWRRHARQPVEFAKSVRTLADMNCKV
MSMEG_0408|M.smegmatis_MC2_155      EPQRILIDNRTGSALGRSTRLDGAYWRRHARQPVEFAKSVRTLADMNCRV
Mvan_1003|M.vanbaalenii_PYR-1       TPQRTLVCNRSGEVLSRHARLDGQYWRRHARQPVRFAESVRTLADLGCRL
MMAR_3025|M.marinum_M               SSRTAFFSSVTGSRLD-TAELDAEYWYRNIRQTVQFDQAVRSACGHGYRT
MUL_2266|M.ulcerans_Agy99           SSRTAFFSSVTGSRLD-TAELDAEYWYRNIRQTVQFDQAVRSACGHGYRT
Mb2074c|M.bovis_AF2122/97           STRTVFFSTVTGNRLD-TAGLDADYWYRNVRQTVLFDQAVRNACEQGYRT
Rv2048c|M.tuberculosis_H37Rv        STRTVFFSTVTGNRLD-TAGLDADYWYRNVRQTVLFDQAVRNACEQGYRT
MAV_2450|M.avium_104                SSRIAFFSTVTGNRLD-TAGLDADYWYRNIRQTVQFDQTVRSAAEHGYRT
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LVEIGPRPVLTAAALSAWP----DPATSPRVIASLRRTTADQRQITEAVA
MAB_0939|M.abscessus_ATCC_1997      LLEIGPQPVLTAAALRAWP----DPATAPRAIASLRRNTADHRQITEAAA
MSMEG_0408|M.smegmatis_MC2_155      LLEIGPRPVLTATALAAWP----DPATTPQVLASLRPTTADHRQITEAVA
Mvan_1003|M.vanbaalenii_PYR-1       LMEIGPQPVLTAAAMRTWP----GTVTAPRVAASMRRKGSDRRQITEALA
MMAR_3025|M.marinum_M               FIESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGREDGGLQRFLASAA
MUL_2266|M.ulcerans_Agy99           FIESSPHPALIAGIEDTYRNCAADSGADPIVVPTLGREDGGLQRFLASAA
Mb2074c|M.bovis_AF2122/97           FIESSPHPALITGVEETFAACTDGD-SEAIVVPTLGRGDGGLHRFLLSAA
Rv2048c|M.tuberculosis_H37Rv        FIESSPHPALITGVEETFAACTDGD-SEAIVVPTLGRGDGGLHRFLLSAA
MAV_2450|M.avium_104                FIESSPHPALVAGIEDTVNDSLPGD-TEAIVIPTLGRDDGGLERFLTSAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          DAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDSRE---PVAAAP
MAB_0939|M.abscessus_ATCC_1997      DAYVLGHLPDFGAFQHAPARKLDLPTYPFERRQYWFSDKRDGDNRDAGNR
MSMEG_0408|M.smegmatis_MC2_155      AAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAIDRDTQTAS
Mvan_1003|M.vanbaalenii_PYR-1       QAYVAGHRPETAARQHGRGRLLDLPTYPFQHRAYWFP--------QGQAR
MMAR_3025|M.marinum_M               AAFVAGVNVDWRGPLDG-AGLVELPTYAFEKRRFWLSGEGVSVDASGLGL
MUL_2266|M.ulcerans_Agy99           AAFVAGVNVDWRGPLDG-AGLVELPTYAFEKRRFWLSGEGVSVDASGLGL
Mb2074c|M.bovis_AF2122/97           SAFVAGVAVNWRGTLDG-AGYVELPTYAFDKRRFWLSAEGSGADVSGLGL
Rv2048c|M.tuberculosis_H37Rv        SAFVAGVAVNWRGTLDG-AGYVELPTYAFDKRRFWLSAEGSGADVSGLGL
MAV_2450|M.avium_104                TAFVAGVNVAWRGVLDG-AGFVELPTYAFDRRRFWLSGEGAAADASGLGL
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QR---GARTETVRLLEDGRIEELAALLGGTV-------------------
MAB_0939|M.abscessus_ATCC_1997      QQNNGGPRTEAVRLLEDGKIEELANLLGGVD-------------------
MSMEG_0408|M.smegmatis_MC2_155      AGSVTPHRTQAVRLLEDGQIEELAALIDGET-------------------
Mvan_1003|M.vanbaalenii_PYR-1       TAPTDPVHTETVRFLDEERIDELAALLDGPT-------------------
MMAR_3025|M.marinum_M               SAGGHALLGAVVELPESGGVVLTGRLALGAHGWLADHAVSGVVVFPGTGF
MUL_2266|M.ulcerans_Agy99           SAGGHALLGAVVELPESGGVVLTGRLALGAHGWLADHAVSGVVVFPGTGF
Mb2074c|M.bovis_AF2122/97           GASEHPLLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDVVLFPGTGF
Rv2048c|M.tuberculosis_H37Rv        GASEHPLLGAVVDLPASGGVVLTGRLSPNVQPWLADHAVSDVVLFPGTGF
MAV_2450|M.avium_104                GTSEHPLLSAVVELPASGGVVLTGRLSPSLQGWLTDHAVSGTVVFPGAGF
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -------DDPFTFDVLNRLAAQHNQQRSTE--------------------
MAB_0939|M.abscessus_ATCC_1997      -------GDQQTLNVLTKLAAQHNLQRTTQ--------------------
MSMEG_0408|M.smegmatis_MC2_155      -------VDEQTLRVLNKLAARHNQQRSTH--------------------
Mvan_1003|M.vanbaalenii_PYR-1       -------GSAQTVDVLSKLAARHRQQRGAQ--------------------
MMAR_3025|M.marinum_M               VELAIRAGDEVGCSVVNELTLRTPLVLPAS----GSVAVQVVVGAAADSA
MUL_2266|M.ulcerans_Agy99           VELAIRAVDEVGCSVVNELTLRTPLVLPAS----GSVAVQVVVGAAADSA
Mb2074c|M.bovis_AF2122/97           VELAIRAGDEVGCSVLDELTLAAPLLLPAT----GSVAVQVVVDAGRDSN
Rv2048c|M.tuberculosis_H37Rv        VELAIRAGDEVGCSVLDELTLAAPLLLPAT----GSVAVQVVVDAGRDSN
MAV_2450|M.avium_104                VELAIRAGDEVGCSTVEELTLQAPLMLPAKDSGIGSVAVQVLVGEADESG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ---------------SIADDRYQIRWETAAEPPVGADAADGITWLLVGDD
MAB_0939|M.abscessus_ATCC_1997      ---------------TIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVADA
MSMEG_0408|M.smegmatis_MC2_155      ---------------VDPDARYEIRWDAIASAAASTGAAA--DWILVGDD
Mvan_1003|M.vanbaalenii_PYR-1       ---------------SIADARYQIRWEKSEAPGAARPTTEATTWLLVTHD
MMAR_3025|M.marinum_M               ERSVSIYSR----TDTDAGSVWVCHAEGTLGADSAQPAADLSAWPPAGAI
MUL_2266|M.ulcerans_Agy99           ERSVSIYSRTDTDTDTDAGSVWVCHAEGTLGADSAQPAADLSAWPPAGAI
Mb2074c|M.bovis_AF2122/97           SRGVSIFSR------ADAQAGWLLHAEGILRPGSVEPGADLSVWPPAGAV
Rv2048c|M.tuberculosis_H37Rv        SRGVSIFSR------ADAQAGWLLHAEGILRPGSVEPGADLSVWPPAGAV
MAV_2450|M.avium_104                RRDVSIFSR------PDSDSPWVCHAQGTLSTGSIEPGADLAAWPPAGAT
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          TDATRPLVDVLAARGHRY--------------------------------
MAB_0939|M.abscessus_ATCC_1997      AGAAQPLLDVLTARGQQH--------------------------------
MSMEG_0408|M.smegmatis_MC2_155      TAAVLEFADALTAGGHRH--------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       SRAAQPIAEVLERRGHPY--------------------------------
MMAR_3025|M.marinum_M               AVDVADGYERLDARGYGYGPAFRGLTAMWARGEELFAEVRLPEAAGSTSG
MUL_2266|M.ulcerans_Agy99           AVDVADGYERLDARGYGYGPAFRGLTAMWARGEELFAEARLPEAAGSTSG
Mb2074c|M.bovis_AF2122/97           TVDVADGYERLATRGYRYGPAFRGLTAMWARGEEIFAEVRLPEAAGGVGG
Rv2048c|M.tuberculosis_H37Rv        TVDVADGYERLATRGYRYGPAFRGLTAMWARGEEIFAEVRLPEAAGGVGG
MAV_2450|M.avium_104                KVDIADGYQRLAARGYGYGPAFQGLTAAWVRGDEVFAEVRLPDAAGGVTG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3025|M.marinum_M               FGVHPALLDAALHTAVI----ANPDAELVLPFSWQGVSLHAAGAASVRVR
MUL_2266|M.ulcerans_Agy99           FGVHPALLDAALHTAVI----ANPDADLVLPFSWQGVSLHAAGAASVRVR
Mb2074c|M.bovis_AF2122/97           FGVHPALLDAVLHAVVI----AGDPDELALPFAWQGVSLHATGASAVRAR
Rv2048c|M.tuberculosis_H37Rv        FGVHPALLDAVLHAVVI----AGDPDELALPFAWQGVSLHATGASAVRAR
MAV_2450|M.avium_104                FGVHPALLDAAMHALIVGHQIAGDTDEVALPFAWQGVSLHAAGASAVRAR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ----------------------------RILGLPKSGAEEHELADTLRDA
MAB_0939|M.abscessus_ATCC_1997      ----------------------------RVLALPVSDADEAELVEALRSA
MSMEG_0408|M.smegmatis_MC2_155      ----------------------------QIVALPGSDADEAQLVDTLRAA
Mvan_1003|M.vanbaalenii_PYR-1       ----------------------------HIVGLPGSDADAAPAEEALRAT
MMAR_3025|M.marinum_M               IAPVGPS------SVSVELADDLGLPVLSVKAMVARPVSEQQMRAVVSAS
MUL_2266|M.ulcerans_Agy99           IAPVGPS------SVSVELADDLGLPVLSVKAMVARPVSEQQMRAVVSAS
Mb2074c|M.bovis_AF2122/97           IAPAGPS------AVSVELADGLGLPVLSVASMVARPVTERQLLAAVSGS
Rv2048c|M.tuberculosis_H37Rv        IAPAGPS------AVSVELADGLGLPVLSVASMVARPVTERQLLAAVSGS
MAV_2450|M.avium_104                LAPAQAPGTAASRAVSLELADGLGLPVLSVRAMVARSVSERQLRAAVSAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AADATDLRIVHVAALDAAESDTSMKSLLRMQHRVLGGTRRLFGAAVAAQL
MAB_0939|M.abscessus_ATCC_1997      ADEDSALRIVHVAALAGQGS-SSAQSLLRIQHQVLGGTRRLFRAAAAAEL
MSMEG_0408|M.smegmatis_MC2_155      SAG--ELYVVHIAAGDGAAA--PMRDLLRVQHRTLGGLRRLFRAANDAEL
Mvan_1003|M.vanbaalenii_PYR-1       VSQ-PRPHILYLAALEEPGG-SAAETLGWMQHRVLAAARRLFQLAATAGA
MMAR_3025|M.marinum_M               GPDRLFEVVWTPMTVAAT-DAAPAYELFESVAAEGDPLSGTYQRTHQALA
MUL_2266|M.ulcerans_Agy99           GPDRLFEVVWTPMTVAAT-DAAPAYELFESIAADGDPLSGTYQRTHQALA
Mb2074c|M.bovis_AF2122/97           GPDRLFEVIWSPASAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQALA
Rv2048c|M.tuberculosis_H37Rv        GPDRLFEVIWSPASAATSPGPTPAYQIFESVAADQDPVAGSYVRSHQALA
MAV_2450|M.avium_104                GPDRLFEVAWAPVTVPAAHGEPPVHQVFESLAAEGDPVGESYRRTHEALA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          RSPMWL----------VTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQ
MAB_0939|M.abscessus_ATCC_1997      RAPIWI----------VTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQ
MSMEG_0408|M.smegmatis_MC2_155      RSPIWL----------VTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPH
Mvan_1003|M.vanbaalenii_PYR-1       RAPIWL----------ITAGAQRITGDETVEPAQTSLWGFGRAAALEQPE
MMAR_3025|M.marinum_M               AVQSWLTEHDSGVLVVATRGAMALAGEDVTDLAGAAVWGLVRSAQTENPG
MUL_2266|M.ulcerans_Agy99           AVQSWLTEHDSGVLVVATRGAMALAGEDVTDLAGAAVWGLVRSAQTENPG
Mb2074c|M.bovis_AF2122/97           AVQSWLTDHESGVLVVATRGAMALPREDVADLAGAAVWGLVRSAQTEHPG
Rv2048c|M.tuberculosis_H37Rv        AVQSWLTDHESGVLVVATRGAMALPREDVADLAGAAVWGLVRSAQTEHPG
MAV_2450|M.avium_104                AVQSWLTEHDSGVLVVVTRGAMALAGEDVTDLSGAAVWGLVRSAQTEHPG
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ----------------------------IWGG------------------
MAB_0939|M.abscessus_ATCC_1997      ----------------------------VWGG------------------
MSMEG_0408|M.smegmatis_MC2_155      ----------------------------IWGG------------------
Mvan_1003|M.vanbaalenii_PYR-1       ----------------------------LWGG------------------
MMAR_3025|M.marinum_M               RLVLVDSDAAVDAAAVATALAVGEPQVVLRNGQPYTARVHASRAADGILV
MUL_2266|M.ulcerans_Agy99           RLVLVDSDAAVDAAAVATALAVGEPQVVLRNGQPYTARVHASRAADGILV
Mb2074c|M.bovis_AF2122/97           RIVLVDSDAATDDAAIAMALATGEPQVVLRGGQVYTARVRGSRAADAILV
Rv2048c|M.tuberculosis_H37Rv        RIVLVDSDAATDDAAIAMALATGEPQVVLRGGQVYTARVRGSRAADAILV
MAV_2450|M.avium_104                RIVLIDSDAALDDSALTAALATGEPQVLLRDGTVYTARVHGSRAVDGIMT
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          -------LADLGGGTSDEWSRLLNRIAATHDPAVMEDQVAVRGSTSYVPR
MAB_0939|M.abscessus_ATCC_1997      -------LADLSDAGTDEWAQFIGRVSVSGEASTREDQLALRGQAVHVPR
MSMEG_0408|M.smegmatis_MC2_155      -------LADLSGADT-EWPRLIARITSPRDG---EDQIALRGDAVYAPR
Mvan_1003|M.vanbaalenii_PYR-1       -------LADVTTGDAEEWSALIDHIVAAPTS---EDQIAVRGREIHVAR
MMAR_3025|M.marinum_M               PPVDGPWRLGLSSAGTFENLQLEPVPNAGAPLGPGQVRVAMRAIAANFRD
MUL_2266|M.ulcerans_Agy99           PPVDGPWRLGLSSAGTFENLQLEPVPNAGAPLGPGQVRVAMRAIAANFRD
Mb2074c|M.bovis_AF2122/97           PPGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMRAIAANFRD
Rv2048c|M.tuberculosis_H37Rv        PPGDGPWRLGLGSAGTFENLRLEPVPNADAPLGPGQVRVAMRAIAANFRD
MAV_2450|M.avium_104                PPEDRPWRLGISSAGTFENLQLEPVPNPDAALQPGQVRVALRAIATNFRD
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          LVHRDTLPSGKPLHLRADA-------------------------------
MAB_0939|M.abscessus_ATCC_1997      LVRREELPSGKPLEVRSDA-------------------------------
MSMEG_0408|M.smegmatis_MC2_155      LVRRTGEPSDTPLPVREDR-------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       LTRCAEKANAAALELRREA-------------------------------
MMAR_3025|M.marinum_M               IMITLGMFTHDALIGGEGAGVVVEIGPEVTEFAVGDAVYGFFPDGSGTLV
MUL_2266|M.ulcerans_Agy99           IMITLGMFTHDALIGGEGAGVVVEIGPEVTEFAVGDAVYGFFPDGSGTLV
Mb2074c|M.bovis_AF2122/97           IMITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFFPDGSGTLV
Rv2048c|M.tuberculosis_H37Rv        IMITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVFGFFPDGSGTLV
MAV_2450|M.avium_104                VMITLGMFTHDALLGGEGAGVVVEVGPGVTEFSVGDSVYGFFPDGSGTLV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3025|M.marinum_M               AGDVRLLLPKPADWSYAEAAAISAVFTTAYYAFVHLANVQPGQRVLVHAA
MUL_2266|M.ulcerans_Agy99           AGDVRLLLPKPADWSYAEAAAISAVFTTAYYAFVHLANVQPGQRVLVHAA
Mb2074c|M.bovis_AF2122/97           AGDVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQPGQRVLIHAG
Rv2048c|M.tuberculosis_H37Rv        AGDVRLLLPMPADWSYAEAAAISAVFTTAYYAFIHLADVQPGQRVLIHAG
MAV_2450|M.avium_104                PGDVRLLQHKPTHWSYPEAAGISAVFTTAYMAFIHLADVKPGQRVLVHAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3025|M.marinum_M               TGGVGMAAVQLARHLGLEVYATASKGKWDILRAMGFDEDHISDSRSLEFE
MUL_2266|M.ulcerans_Agy99           TGGVGMAAVQLARHLGLEVYATASKGKWDILRAMGFDEDHISDSRSLEFE
Mb2074c|M.bovis_AF2122/97           TGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEFE
Rv2048c|M.tuberculosis_H37Rv        TGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHISDSRSLEFE
MAV_2450|M.avium_104                AGGVGMAAVQLARHLGLEVFATASRGKWDTLRAMGFDDDHIGDSRTLEFE
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3025|M.marinum_M               EKFREVTGGRGVDVVLDSLAGEFVDASLRLLGPGGVFLEMGKTDIRDPGV
MUL_2266|M.ulcerans_Agy99           EKFREVTGGRSVDVVLDSLAGEFVDASLRLLGPGGVFLEMGKTDIRDPGV
Mb2074c|M.bovis_AF2122/97           DKFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGV
Rv2048c|M.tuberculosis_H37Rv        DKFRAATGGRGFDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGV
MAV_2450|M.avium_104                DKFRSATGGAGMDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGV
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       --------------------------------------------------
MMAR_3025|M.marinum_M               IAQEYPGVRYRAFDLFEPGRPRMHQYMLDLAGLFDAGVLRPLPVTAFDVR
MUL_2266|M.ulcerans_Agy99           IAQEYPGVRYRAFDLFEPGRPRMHQYMLDLAGLFDAGVLRPLPVTAFDVR
Mb2074c|M.bovis_AF2122/97           IAQQYPGVRYRAFDLFEAGPDRIAQILAELATLFGDGVLRPLPVTTFDVR
Rv2048c|M.tuberculosis_H37Rv        IAQQYPGVRYRAFDLFEPGRPRMHQYMLELATLFGDGVLRPLPVTTFDVR
MAV_2450|M.avium_104                VAREYPGVRYRAFDLFEPGRPRMRQWMVELAGLFDAGVLNPLPVTTFDIR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          ---------------------------------TYLVTGGLGSLGLEIAG
MAB_0939|M.abscessus_ATCC_1997      ---------------------------------TYLVTGGLGSIGLEIAG
MSMEG_0408|M.smegmatis_MC2_155      ---------------------------------TYLVTGGLGAIGLEVAG
Mvan_1003|M.vanbaalenii_PYR-1       ---------------------------------TYLVTGGLGALGLEVAE
MMAR_3025|M.marinum_M               RAPAALRYLSQARHIGKVVMTMPADQGGALGGGTVLITGGTGMAGSALAR
MUL_2266|M.ulcerans_Agy99           RAPAALRYLSQARHVGKVVMTMPADQGGALGGGTVLITGGTGMAGSALAR
Mb2074c|M.bovis_AF2122/97           RAPAALRYLSQARHTGKVVMLMPG----SWAAGTVLITGGTGMAGSAVAR
Rv2048c|M.tuberculosis_H37Rv        RAPAALRYLSQARHTGKVVMLMPG----SWAAGTVLITGGTGMAGSAVAR
MAV_2450|M.avium_104                RGRAALRYLSQARHIGKVVMTVPG----ALSAGTVLITGGTGMAGSTLAR
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          YLAA-NGAGHLVLTSRRTPDEAAASRIEALRERHGCEVRVVTADVADAHA
MAB_0939|M.abscessus_ATCC_1997      YLAG-RGAKHLVLTSRREPGEAARQRIDALAA-QGCEVRAVTADVADGHD
MSMEG_0408|M.smegmatis_MC2_155      YLAS-HGAGHVVLTSRREPGDDARRRLDGLREQYACDVRVITADVADAHD
Mvan_1003|M.vanbaalenii_PYR-1       FLAS-HGAGHLVLTGRRSASDTVRQRIDAMRERFDCQVLVATADVADRDD
MMAR_3025|M.marinum_M               HLVAHHGVAHLVLISRRGPAAPGATELVAELSAAGAQVEVVACDAADRPA
MUL_2266|M.ulcerans_Agy99           HLVAHHGVAHLVLISRRGPAAPGATELVAELSAAGAQVEVVACDAADRPA
Mb2074c|M.bovis_AF2122/97           HVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRAA
Rv2048c|M.tuberculosis_H37Rv        HVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQVVACDAADRAA
MAV_2450|M.avium_104                HLVTGHGVRDLALLSRTGPDAPGAAEFVAELEAAGARVQVIACDAADRAA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          VARLLATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVDRVFAGKVWGAW
MAB_0939|M.abscessus_ATCC_1997      VARLLAGIQAELPPLAGIVHAAGEIGTTPLSDLEDAEVDRVFAGKVWGAW
MSMEG_0408|M.smegmatis_MC2_155      VARLMTTVAAELPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAW
Mvan_1003|M.vanbaalenii_PYR-1       VARLFSTMRSELPPLAGIVHAAGEIGTSPLRTLDDAEMDRVFAGKVWGAV
MMAR_3025|M.marinum_M               LAKVIAEIPAQRP-LSAVVHAGGVLDDAVISSLTPERVDTVLRAKVDAAW
MUL_2266|M.ulcerans_Agy99           LAKVIAENPAQRP-LSAVVHAGGVLDDAVISSLTPERVDTVLRAKVDAAW
Mb2074c|M.bovis_AF2122/97           LAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAAW
Rv2048c|M.tuberculosis_H37Rv        LAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDVVLRSKVDAAW
MAV_2450|M.avium_104                LAGVIAGISAERP-LSGVIHAAGVLDDAMITSLTPERIDAVLRAKVDAAW
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          HLSEATSDLQ--LDFFISTSSIASVWGGFGQAAYGAANAFLDGLAWRLRE
MAB_0939|M.abscessus_ATCC_1997      HLSEAAAGLK--LDFFINTSSIAAVWGGYGQTAYSAANAFLDGLAWRLRE
MSMEG_0408|M.smegmatis_MC2_155      HLSEALTDLRTDLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLAWRLRE
Mvan_1003|M.vanbaalenii_PYR-1       YLCEEVADMG--LDFFLATSSIASVWGSHGQTAYGAANAFLDGLADSLRA
MMAR_3025|M.marinum_M               NLHELTRDLD--LSAFVMFSSMAGVVGSSGQANYAAANTFVDGLAAHRRA
MUL_2266|M.ulcerans_Agy99           NLHELTRDLD--LSAFVMFSSMAGVVGSSGQANYAAANTFVDGLAAHRRA
Mb2074c|M.bovis_AF2122/97           HLHELTRDLD--VSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRRA
Rv2048c|M.tuberculosis_H37Rv        HLHELTRDLD--VSAFVMFSSMAGLVGSSGQANYAAANSFLDALAAHRRA
MAV_2450|M.avium_104                NLHELTRDMN--LSAFVMFSSMAGLVGSSGQGNYAAANSFLDALAAHRRA
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          QGVAGVSVNFGPWS-----AGMADAQSRARLEQRGIKTLSPADALAGLSD
MAB_0939|M.abscessus_ATCC_1997      QGIAGTSVNFGPWS-----AGMADAESRARLEQRGIKTLSPTDALAGLAD
MSMEG_0408|M.smegmatis_MC2_155      RGVTAVSVNFGPWA-----AGMADAESRARLEQRGVRTLSPAEALAGMAD
Mvan_1003|M.vanbaalenii_PYR-1       RGIPGISVNFGPWA-----AGMADAKAREQLSRRGVKTLAPADALAGMAD
MMAR_3025|M.marinum_M               HGLPAISLGWGLWDQASDMTGGMDAADRARLGREGVLALSSDEAMELFDT
MUL_2266|M.ulcerans_Agy99           HGLPAISLGWGLWDQASDMTGGMDAADRARLGREGVLALSSDEAMELFDT
Mb2074c|M.bovis_AF2122/97           HGLPAISLGWGLWDQASAMTSGLDAADLARLGREGVLALSTAEALELFDT
Rv2048c|M.tuberculosis_H37Rv        HGLPAISLGWGLWDQASAMTGGLDAADLARLGREGVLALSTAEALELFDT
MAV_2450|M.avium_104                HGLPAISLAWGLWDQASAMTGGLDAADLARLGRDGILALSSDEAMELFDT
MLBr_00135|M.leprae_Br4923          ------------------MTASVEGADQK---------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AVISAAP---HPVVARVDWSRFLPLYQQAGRRGFLAELERELPAAPAQQG
MAB_0939|M.abscessus_ATCC_1997      VVAASGSNAVQGVIARIDWARFLPLYQQAGKRGFLAELDREVPSHLA--G
MSMEG_0408|M.smegmatis_MC2_155      VVAGPVQ----GVVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATGAA
Mvan_1003|M.vanbaalenii_PYR-1       VIAASTA---HAVVARIDWATFLPVYQLQRRRAFLSQLEREVPDVPD--A
MMAR_3025|M.marinum_M               ALIVNQA-----FLAPARIDLAALRAHAVAVPPMFSDLVSAPTRRQVDDA
MUL_2266|M.ulcerans_Agy99           ALIVNQA-----FLAPARIDLAALRAHAVAVPPMFSDLVSAPTRRQIDAA
Mb2074c|M.bovis_AF2122/97           AMIVDEP-----FLAPARIDLTALRAHAVAVPPMFSDLASAPTRRQVDDS
Rv2048c|M.tuberculosis_H37Rv        AMIVDEP-----FLAPARIDLTALRAHAVAVPPMFSDLASAPTRRQVDDS
MAV_2450|M.avium_104                ALIVDEP-----FLAPARIDLGALRAHAVAVPPMFADLVNAPTRRRVDDS
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          PAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTRVDAAEIREDA
MAB_0939|M.abscessus_ATCC_1997      VAGAQSGSTQLVERLANAPVQQRKKLLTDYLRDAVAEVTRVDVSEIREDA
MSMEG_0408|M.smegmatis_MC2_155      APATVPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEA
Mvan_1003|M.vanbaalenii_PYR-1       SAPAPSGTTRFVEELTLAPVEQRRKLVLEYLRAAVAEVTRVDAAEIRDEA
MMAR_3025|M.marinum_M               LAAAKSKSALAHRLHGLPEPEQHAVVLDLVRSHIATVLGTITPEAIDPDK
MUL_2266|M.ulcerans_Agy99           LATAKSKSALAHRLHGLPELEQHAVVLDLVRSHIATVLGTITPEAIDPDK
Mb2074c|M.bovis_AF2122/97           VAAAKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDK
Rv2048c|M.tuberculosis_H37Rv        VAAAKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITPEAIDPDK
MAV_2450|M.avium_104                LAAAKSKSALAHRLDGLPEAEQHAVLLELVRSHIATVLGSPTAEAIDPDK
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYLLGDVL
MAB_0939|M.abscessus_ATCC_1997      GFFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGDVL
MSMEG_0408|M.smegmatis_MC2_155      GFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVL
Mvan_1003|M.vanbaalenii_PYR-1       GFFDLGMDSLMAIELRRRLEQGLGKELPVTLAMDHPHLSDAAEYVLGDVL
MMAR_3025|M.marinum_M               AFQELGFDSLTAVEMRNRIKTVTGLSLSPTLIFDYPTPNGLANYIRAELA
MUL_2266|M.ulcerans_Agy99           AFQELGFDSLTAVEMRNRIKTVTGLSLSPTLIFDYPTPNGLANYIRAELA
Mb2074c|M.bovis_AF2122/97           AFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELA
Rv2048c|M.tuberculosis_H37Rv        AFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELA
MAV_2450|M.avium_104                AFQELGFDSLTAVEMRNRLKTATGLALSPTLIFDYPTPNALAGYIRTELA
MLBr_00135|M.leprae_Br4923          -------------------------------------SEKLISYLKKVVV
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          GLTEAAT-APKAATVVSTAADEPIAIVAVSCRFPG-APNPEAFWDLLSGG
MAB_0939|M.abscessus_ATCC_1997      GLAEQAKPAAQLASAVTGRTDEPIAIVAVSCRFPG-APDPEAFWDVLSGG
MSMEG_0408|M.smegmatis_MC2_155      GLGEQTN--VRQASTVTARTDDPIAVVAVSCRFPG-APDPESFWELLAGG
Mvan_1003|M.vanbaalenii_PYR-1       GLSEHTV--AQPDTPSTVRTDDPIAIVGMACRFPG-ADDTDAFWSVLAEG
MMAR_3025|M.marinum_M               GAPQEVK----HTPAVRVTGDDPIAIVGMSCRYPGGIESPDDLWDMLMAR
MUL_2266|M.ulcerans_Agy99           GAPQEVK----HTPAVRVTGDDPIAIVGMSCRYPGGIESPDDLWDMLMAR
Mb2074c|M.bovis_AF2122/97           GLPQEIK----HTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQG
Rv2048c|M.tuberculosis_H37Rv        GLPQEIK----HTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQG
MAV_2450|M.avium_104                GAPQETT----HAPVVRATDDDPIAIVGMSCRFPGGVDSPEALWQMVAEG
MLBr_00135|M.leprae_Br4923          ELDETRA----RLREYEQRATEPVAVVGIGCRFPGGVDSPDRLWDVVSEC
TH_4621|M.thermoresistible__bu      ------------VNIVGDTPVNAVAVIGMACRLPGGIDSPQRLWEALLRG
                                                         :.:*::.:.** **   ..: :*. :   

Mflv_0405|M.gilvum_PYR-GCK          VDAIREVPEDR-FDIDEFYDPDPDAAGKTYTRYGGFLDHIDEFDPEFFGL
MAB_0939|M.abscessus_ATCC_1997      VDAIREVPEDR-FDIDEFYDPDPEVAGKTYTRFGGFLDGIDGFDPEFFGI
MSMEG_0408|M.smegmatis_MC2_155      VDAIREVPEDR-WDIDEFYDPDPDTPGKTYTRFGGFLDGIDGFDPEFFGI
Mvan_1003|M.vanbaalenii_PYR-1       ADLIREIPDDR-FDINEFYDPDPEAAGKIYSRYGGFLDGVDGFDPEFFGI
MMAR_3025|M.marinum_M               RDVLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFDPAFFGV
MUL_2266|M.ulcerans_Agy99           RDVLSDFPADRGWDLAGLFNPDPDVPGACYTRTGGFVDRVGDFEPAFFGV
Mb2074c|M.bovis_AF2122/97           RDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGV
Rv2048c|M.tuberculosis_H37Rv        RDVLSEFPADRGWDLAGLYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGV
MAV_2450|M.avium_104                RDVLSEFPTDRGWDLAGVYNPDPDVPGTCYTRTGGFVDNVADFDPAFFGI
MLBr_00135|M.leprae_Br4923          RDVVSEFPTDRGWDVDGLFDPDPDAEGKTYTRWGAFLDDAAGFDAGFFGI
TH_4621|M.thermoresistible__bu      DDMVTEIPVDR-WDADDYFDPEPGVPGRTVSRWGAFLDDVAGFDPEFFGI
                                     * : :.* ** :*    ::*:* . *   :* *.*:*    *:. ***:

Mflv_0405|M.gilvum_PYR-GCK          SPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRTGVFVGVAANEYA
MAB_0939|M.abscessus_ATCC_1997      SPREAVWIEPQQRLMLETVWEGLERAGYSPAALRGSRTGIFAGVGANEYA
MSMEG_0408|M.smegmatis_MC2_155      SPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGVAANEYA
Mvan_1003|M.vanbaalenii_PYR-1       SPREAVWIDPQQRLVLETAWEGLERAGYSAAALRGSRSGVYVGVGANEYS
MMAR_3025|M.marinum_M               GPSEALAMDPQQRMFLELSWEALERAGIEPGGLRGSATGVFAGVMTQGYG
MUL_2266|M.ulcerans_Agy99           GPSEALAMDPQQRMFLELSWEALERAGIEPGGLRGSATGVFAGVMTQGYG
Mb2074c|M.bovis_AF2122/97           GPSEALAMDPQQRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYG
Rv2048c|M.tuberculosis_H37Rv        GPSEALAMDPQHRMLLELSWEALERAGIDPTGLRGSATGVFAGVMTQGYG
MAV_2450|M.avium_104                APSEALAMDPQQRMFLELSWEALERAGIDPVKLRGSATGMFAGVYTQGYG
MLBr_00135|M.leprae_Br4923          APSEVLAMDPQQRLMLEVSWEALEYAGIDPLSLRGSATGVFTGIFAPSYG
TH_4621|M.thermoresistible__bu      SEREAISIDPQQRLLLETSWEAMEHAGLTPADVEGSSTGVFVGLSHDDYA
                                    .  *.: ::**:*:.**  **.:* **  .  :.** :*::.*:    *.

Mflv_0405|M.gilvum_PYR-GCK          HLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTACSSSLV
MAB_0939|M.abscessus_ATCC_1997      HLLSSESIDKIEPYFITGNALNAISGRVAFALGFEGPAVAVDTACSSALV
MSMEG_0408|M.smegmatis_MC2_155      HLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALV
Mvan_1003|M.vanbaalenii_PYR-1       HLLSGGSLDGIEAQFITGNALNVIAGRVSFTLGLEGPAVAVDTACSSSLV
MMAR_3025|M.marinum_M               MFAAEP----VEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLV
MUL_2266|M.ulcerans_Agy99           MFAAEP----VEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLV
Mb2074c|M.bovis_AF2122/97           MFAAEP----VEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLV
Rv2048c|M.tuberculosis_H37Rv        MFAAEP----VEGFRLTGQLSSVASGRVAYVLGLEGPAVSVDTACSSSLV
MAV_2450|M.avium_104                MGAAPI----AEGFRLTGQSSSVASGRVSYVLGLEGPAVSVDTACSSSLV
MLBr_00135|M.leprae_Br4923          SRDTGG----LQGYGLTGTAVSVASGRVSYVLGLEGPAVSVDTACSSSLV
TH_4621|M.thermoresistible__bu      LLTSDAG-ALEEAYGFTGSAFSMASGRIAYRLGVHGPAVTVDTACSSSLL
                                       :       :   :**   .  :**::: **..****:*******:*:

Mflv_0405|M.gilvum_PYR-GCK          AVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFD
MAB_0939|M.abscessus_ATCC_1997      AVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGRCKTFD
MSMEG_0408|M.smegmatis_MC2_155      AVHQACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFD
Mvan_1003|M.vanbaalenii_PYR-1       AVHQACQGLQSGDCDLALAGGVNVLLSPATTIATSRARMLSPDGRCKTFD
MMAR_3025|M.marinum_M               ALHMAVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLSADGRCKAFA
MUL_2266|M.ulcerans_Agy99           ALHMAVQSLRSGECDLALAGGVTINATPDIFVEFSRWRGLSADGRCKAFA
Mb2074c|M.bovis_AF2122/97           ALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFA
Rv2048c|M.tuberculosis_H37Rv        ALHMAVGSLRSGECDLALAGGVTVNATPDIFVEFSRWRGLSPDGRCKAFA
MAV_2450|M.avium_104                ALHMAVQSLRSGECDLALAGGVTVNATPDIFVEFSRMRGLSVDGRCKAYA
MLBr_00135|M.leprae_Br4923          AIHWAMSSLRSGECDLALAGGVTVMGLPSIFVGFSRQRGLAADGRCKAFA
TH_4621|M.thermoresistible__bu      AVHMACRSLQVGESDLALAGGAMVMLEPRKYTSASGLGMLSPTGRCHAFD
                                    *:* *  .*: *:.*:*****. :   *      *    *:  ***::: 

Mflv_0405|M.gilvum_PYR-GCK          ASADGYVRSEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGASSGLTV
MAB_0939|M.abscessus_ATCC_1997      ASADGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASSGLTV
MSMEG_0408|M.smegmatis_MC2_155      ASADGYVRSEGCGVLVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTV
Mvan_1003|M.vanbaalenii_PYR-1       AAADGYVRGEGCGILVLKRLSDAVRDGDRIQAVIRGSAVNQDGASGGLTV
MMAR_3025|M.marinum_M               GAADGTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQDGASNGLTA
MUL_2266|M.ulcerans_Agy99           GAADGTGFSEGGGMLVVERLSDAQRLGHPVLALVRGSAVNQDGASNGLTA
Mb2074c|M.bovis_AF2122/97           AAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTA
Rv2048c|M.tuberculosis_H37Rv        AAADGTGFSEGGGMLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTA
MAV_2450|M.avium_104                GAADGTGFSEGGGMLVVERLSDARRLGHPVLAVVRGSAVNQDGASNGLTA
MLBr_00135|M.leprae_Br4923          RAADGTGWGEGAGVVVLERLSDAQRLGHTVLAVVRGSAVNQDGASNGLTA
TH_4621|M.thermoresistible__bu      VAADGFVRSEGSVMLLLKRLPDALRDNDRILAVVRGTAANQDGRTENIST
                                     :***   .**  :::::**.** * .. : *:: .::.**** : .::.

Mflv_0405|M.gilvum_PYR-GCK          PNGGAQQRLIGTVLARAGITGGEVDYLEAHGTGTPLGDPIEVQAAAAAYA
MAB_0939|M.abscessus_ATCC_1997      PNGGAQQRLIGSVLARAGLVGGDVDYLEAHGTGTPLGDPIEVQAAAAAYG
MSMEG_0408|M.smegmatis_MC2_155      PNGGAQQRLIEATLARAGLSGADVDYLEAHGTGTPLGDPIEVQAAAAAYG
Mvan_1003|M.vanbaalenii_PYR-1       PNGGAQQRVIAAALTRAGLSGSDIDYLEAHGTGTSLGDPIEVQAAGAVLG
MMAR_3025|M.marinum_M               PNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYG
MUL_2266|M.ulcerans_Agy99           PNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYG
Mb2074c|M.bovis_AF2122/97           PNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYG
Rv2048c|M.tuberculosis_H37Rv        PNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYG
MAV_2450|M.avium_104                PNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYG
MLBr_00135|M.leprae_Br4923          PNGLAQQRVIQAALTNAGLSSADVDVVEAHGTATTLGDPIEAQALLATYG
TH_4621|M.thermoresistible__bu      PSIQAQADVYRSALAVAGVDPATVGMVEAHGTGTPVGDPIEYNSLTQVYG
                                    *.  :*  :  :.*: **:  . :. :*.***.*.:***** ::   . .

Mflv_0405|M.gilvum_PYR-GCK          GARDAD----RPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHETLPQSL
MAB_0939|M.abscessus_ATCC_1997      GSRDAD----RPLLMGSVKSNIGHTESASGAAGLIKVVLSLQNGVLPQSL
MSMEG_0408|M.smegmatis_MC2_155      AGRDAD----RPLLMGSVKTNIGHTESASGAAGLIKVVLSLQHGVLPQSL
Mvan_1003|M.vanbaalenii_PYR-1       AGRDPD----RPLLMGSVKTNVGHLESASGVAGLIKVVLSLQHEMLPRHL
MMAR_3025|M.marinum_M               QDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVLPATL
MUL_2266|M.ulcerans_Agy99           QDRGSAGAAGKALWLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVLPATL
Mb2074c|M.bovis_AF2122/97           QDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPATL
Rv2048c|M.tuberculosis_H37Rv        QDRGEP---GEPLWLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPATL
MAV_2450|M.avium_104                QDRGQP------LWLGSIKSNMGHTQAAAGVAGVIKMVLAMRHELLPATL
MLBr_00135|M.leprae_Br4923          QGRPAD----QPLWVGSIKSNMGHTQAAAGVAGVIKMVQAMRHHVMPATL
TH_4621|M.thermoresistible__bu      KTGPCA--------LTSVKTNFGHAESAAGALGMMKAILALQHGVVPQNL
                                                  : *:*:*.** ::*:*. *::* : ::::  :*  *

Mflv_0405|M.gilvum_PYR-GCK          HFDTPSPHIPWDSLPVRVVDTAMPWQ---PNGRPRRAGVSSFGFTGTNAH
MAB_0939|M.abscessus_ATCC_1997      HFDNPSPHIPWESLPVRVVDKAIPWQ---ANGRPRRAGVSSFGFTGTNAH
MSMEG_0408|M.smegmatis_MC2_155      HFENPSPHIPWDALPVRVIDEPVPWQ---TNGRVRRAGVSSFGFTGTNAH
Mvan_1003|M.vanbaalenii_PYR-1       HFKTPSPHIPWDRLAVRVVAEPTPWR---ADGRPRRAGVSSFGFSGTNAH
MMAR_3025|M.marinum_M               HVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAH
MUL_2266|M.ulcerans_Agy99           HVDVPSPHVDWSAGAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAH
Mb2074c|M.bovis_AF2122/97           HVDVPSPHVDWSAGAVELLTAPRVWP---AGARTRRAGVSSFGISGTNAH
Rv2048c|M.tuberculosis_H37Rv        HVDVPSPHVDWSAGAVELLTAPRVWP---AGARTRRAGVSSFGISGTNAH
MAV_2450|M.avium_104                HVDEPSPHVDWSAGAVSLLTEAQPWP----GERPRRAGVSSFGISGTNAH
MLBr_00135|M.leprae_Br4923          HVDEPSPRVDWTTGAVSVLTEARDWS---VEGRPRRAGVSSFGISGTNAH
TH_4621|M.thermoresistible__bu      HFTRLPDEMAAIETNLFVPQATTLWP--VREGCPRRAAVSSYGMSGTNVH
                                    *.   . .:      : :   .  *         ***.***:*::***.*

Mflv_0405|M.gilvum_PYR-GCK          VLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARSPEALV
MAB_0939|M.abscessus_ATCC_1997      VLIEEAPQPQATP----------DEDDASTPQSAPVSVLPLSARSPEALA
MSMEG_0408|M.smegmatis_MC2_155      VLVEEAPPQLHTADAAP----VEPAATAEAGTDDSPQVLALSARSPEALV
Mvan_1003|M.vanbaalenii_PYR-1       VVLEEPPAQSADLRQPPTDGKDGAAGLESATAPEPAGVLPISARSPEALT
MMAR_3025|M.marinum_M               VIVEAAP---------------RVEVGGSSGGAVPVVPWVVSAKSGSALG
MUL_2266|M.ulcerans_Agy99           VIVEAAP---------------RVEVGGSSGGAVPVVPWVVSAKSGSALG
Mb2074c|M.bovis_AF2122/97           VIIEAVP---------------VVPRR-EAGWAGPVVPWVVSAKSESALR
Rv2048c|M.tuberculosis_H37Rv        VIIEAVP---------------VVPRR-EAGWAGPVVPWVVSAKSESALR
MAV_2450|M.avium_104                VIIEAVP---------------AVEPAHADAPALPVLPWVVSAKSAAALR
MLBr_00135|M.leprae_Br4923          VILEEAPTP------------VEASYSTADQQRLSVVPWVVSGRSTAALM
TH_4621|M.thermoresistible__bu      AVLEQAPEP------------VQRPEESADTDAAGPLVFALSSTSAEELR
                                    .::*  *                                 :*. *   * 

Mflv_0405|M.gilvum_PYR-GCK          ALAQRYETWLTAH-PEADLADVCRTAGTGRSHFEHRAALVVDSVESARIA
MAB_0939|M.abscessus_ATCC_1997      AVAQRYESWLAAH-PDVDLEDVCLTAGRGRSHFEHRAALVVDSIQTAREG
MSMEG_0408|M.smegmatis_MC2_155      ELARRYDDWLSAT-PGLDIADVCHTAGVGRSHFEYRAALVVDSVERAREG
Mvan_1003|M.vanbaalenii_PYR-1       ALARRYESWLTAH-PDADIADVCYTAGAGRSHFEHRAALVVDSVDGARDL
MMAR_3025|M.marinum_M               AQAARLAAHVRSH-DELDVADVGWSLA-GRSTFEHRAVVLGVDRDGLLAG
MUL_2266|M.ulcerans_Agy99           AQAARLAAHVRSH-DELDVADVGWSLA-GRSTFEHRAVVLGADRDGLLAG
Mb2074c|M.bovis_AF2122/97           GQAARLAAYVRGD-DGLDVADVGWSLA-GRSVFEHRAVVVGGDRDRLLAG
Rv2048c|M.tuberculosis_H37Rv        GQAARLAAYVRGD-DGLDVADVGWSLA-GRSVFEHRAVVVGGDRDRLLAG
MAV_2450|M.avium_104                AQAARLAEYVRAQ-GELDIADVGWTLA-GRATFEHRAVVVGGDRDRLLAG
MLBr_00135|M.leprae_Br4923          AQASRLAFYVQAD-PEVDPVDVGCALA-ARSVFEHRAVVVGESREQLIAG
TH_4621|M.thermoresistible__bu      RTAGRLAEWVEAHTDEVVPADLAYTLARRRAHRPVRTTVIADGVEALTAG
                                      * *    : .        *:  : .  *:    *:.::  . :     

Mflv_0405|M.gilvum_PYR-GCK          LTDLAQNRLR-PGVVRGEHLNHPTTAWMFTGQGSQYPGMARELFDTEPVF
MAB_0939|M.abscessus_ATCC_1997      LLELAQNRLR-PGVVRGEHTNHPTTAWLFTGQGSQYPGMARELFDAEPVF
MSMEG_0408|M.smegmatis_MC2_155      LAALAEGRTP-AGVVRGEHVHRPTTAWLFTGQGSQYPGMARELFDTQPVF
Mvan_1003|M.vanbaalenii_PYR-1       LAGLAEDRLG-PGAVRGVCGDPPKTAWLFTGQGSQYPGMARELFDTEPVF
MMAR_3025|M.marinum_M               LDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHAGYPVF
MUL_2266|M.ulcerans_Agy99           LDELAGDEFGGASVIRGVAGAAGKTVFVFPGQGSQLLGMGMGLHAGYPVF
Mb2074c|M.bovis_AF2122/97           LDELAGDQLG-GSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVF
Rv2048c|M.tuberculosis_H37Rv        LDELAGDQLG-GSVVRGTATAAGKTVFVFPGQGSQWLGMGMGLHAGYPVF
MAV_2450|M.avium_104                LDELAADDPA-ASIIRGVATPAGKTVFVFPGQGSQTLGMGRQLHAGYPVF
MLBr_00135|M.leprae_Br4923          LAGLAVGESG-AGVAIGQAAPLGKTVVVFPGQGAQRIGMGRELCSQLPVF
TH_4621|M.thermoresistible__bu      LREVADGDAP---YQPAVGMDDKAPVWVFSGQGSQWAGMGAELLATEQVF
                                    *  :* .         .       .. :*.***:*  **.  *     **

Mflv_0405|M.gilvum_PYR-GCK          ADTVTRCADAVADLLPRPLLDVMFAGGREAGVPPTETLRHTSFAQPALFA
MAB_0939|M.abscessus_ATCC_1997      AETVTRCAEAVKDIVTRPLLEVMFATDRETGGKAGEALRHTSFAQPALFA
MSMEG_0408|M.smegmatis_MC2_155      AQTVRQCAEAVADMLPRPLLDVLFATDRET----ADLLQHTSFAQPALFA
Mvan_1003|M.vanbaalenii_PYR-1       RDTVTRCAEAIGDTLPRPLLEVLFDTDGDN----GQTLRHTSYAQPALFA
MMAR_3025|M.marinum_M               AEAFNTVVGELDRHLLRPLREVIWGH-------DENLLNTTEFAQPALFA
MUL_2266|M.ulcerans_Agy99           AEAFNTVVGELDRHLLRPLREVIWGH-------DENLLNTTEFAQPALFA
Mb2074c|M.bovis_AF2122/97           AEAFNTVVGELDRHLLRPLREVMWGH-------DENLLNSTEFAQPALFA
Rv2048c|M.tuberculosis_H37Rv        AEAFNTVVGELDRHLLRPLREVMWGH-------DENLLNSTEFAQPALFA
MAV_2450|M.avium_104                AEAFDAVVAELDRHLLRPLRDVIWGD-------DENVLNSTEFAQPALFA
MLBr_00135|M.leprae_Br4923          AEEFDAVTGELDRHMRLPLRDVVWGA-------DAGLLDSTEFAQPALFA
TH_4621|M.thermoresistible__bu      AAKIAEIEPLVARESGFSVTEAMTAS---------ETVTGIDRVQPTLFA
                                       .      :      .: :.:              :   . .**:***

Mflv_0405|M.gilvum_PYR-GCK          VEMGLARLWQSWGIVPDVVLGHSVGQYAAACVAGVFSLEDGARLMAERGR
MAB_0939|M.abscessus_ATCC_1997      VEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSIEDGARLIAERGR
MSMEG_0408|M.smegmatis_MC2_155      VEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGR
Mvan_1003|M.vanbaalenii_PYR-1       IEMGLARLWQARGIEPDVVLGHSVGQYAAACVAGVFGLEDGARLVADRGR
MMAR_3025|M.marinum_M               VEVALYRLLESWGVRPDFVMGHSVGELSAAHVAGVLSLENAAVLVAARGR
MUL_2266|M.ulcerans_Agy99           VEVALYRLLESWGVRPDFVMGHSVGELSAAHVAGVLSLENAAVLVAARGR
Mb2074c|M.bovis_AF2122/97           VEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGR
Rv2048c|M.tuberculosis_H37Rv        VEVALFRLLGSWGVRPDFVMGHSIGELSAAHVAGVLSLENAAVLVAARGR
MAV_2450|M.avium_104                VEVALFRLLESWGVRPDFVMGHSIGELSAAHVAGVLSLQNAAVLVAARGR
MLBr_00135|M.leprae_Br4923          VEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAGVLAPADAAMLVVARGR
TH_4621|M.thermoresistible__bu      IQVALAATMQSYGVRPGAVIGHSLGEVAAAVVAGALSLEDGVKVICRRSR
                                    :::.*       .: *. *:***:*: :** ***.:.  :.. ::  *.*

Mflv_0405|M.gilvum_PYR-GCK          LFGSLPEGGRMVAVFADAKRVEQVAADF--PRVSVGAYNGPN-TVLSGPG
MAB_0939|M.abscessus_ATCC_1997      LFGGLPAGGRMVAVFSDAKHVEQIAGEF--PRVSVGAYNGPN-TVLSGPG
MSMEG_0408|M.smegmatis_MC2_155      MFGSLPEGGRMVAVFADAEHVEQVAGEF--PRVSVGAYNGPN-TVLSGPG
Mvan_1003|M.vanbaalenii_PYR-1       LFGGLPVGGRMVAVFTDAEVVEDFADEF--PQVSVAAYNGPN-TVLAGPA
MMAR_3025|M.marinum_M               LMQALPDGGAMIAVQATEQEVLPLLG----AQVSIAAINGPASVVISGAQ
MUL_2266|M.ulcerans_Agy99           LMQALPDGGAMIAVQATEQEVLPLLG----AQVSIATINGPASVVISGAQ
Mb2074c|M.bovis_AF2122/97           LMQALPAGGAMVAVQAAEEEVRPLLS----AEVDIAAVNGPASLVISGAQ
Rv2048c|M.tuberculosis_H37Rv        LMQALPAGGAMVAVQAAEEEVRPLLS----AEVDIAAVNGPASLVISGAQ
MAV_2450|M.avium_104                FMQALPEGGAMIAVQATEAQVRPLLG----PDVGIAAVNGPAAVVISGDH
MLBr_00135|M.leprae_Br4923          LMQSMPAGGTMWAVAASEDEVVSLLG----EGVGIAAINAPESVVISGPQ
TH_4621|M.thermoresistible__bu      LCLRLAGAGAMAAIELPAQAVREFLAARGVDDVVLSVIASPESTVIGGAT
                                    :   :. .* * *:      *  .        * :..  .*   *:.*  

Mflv_0405|M.gilvum_PYR-GCK          EDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFESYAAQLQFAAP
MAB_0939|M.abscessus_ATCC_1997      EDLEQAVARFQEEGIRCTWLETSHAFHSELLDPILDEFESYAAQVQFAAP
MSMEG_0408|M.smegmatis_MC2_155      EDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLDEFEAYAAQFQFAAP
Mvan_1003|M.vanbaalenii_PYR-1       SDLEQIVAGCSGEGIRTTWLDTSHAFHSALLDPVLDEFESCAARLAYAAP
MMAR_3025|M.marinum_M               DAVSAVAEQLRADGRRVHRLAVSHAFHSPLMDPMIDEFATVAGELTVNAP
MUL_2266|M.ulcerans_Agy99           DAVSAVAEQLRADGRRVHRLAVSHAFHSPLMDPMIDEFATVAGELTVNAP
Mb2074c|M.bovis_AF2122/97           NAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRP
Rv2048c|M.tuberculosis_H37Rv        NAVAAVADQLRADGRRVHQLAVSHAFHSPLMDPMIDEFAAVAAGIAIGRP
MAV_2450|M.avium_104                DAAVAIAERLRAEGHRVHRLSVSHAFHSPLMEPMIDEFGTVAAGLAIDKP
MLBr_00135|M.leprae_Br4923          AAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLEEFVRVAAQVEVRKP
TH_4621|M.thermoresistible__bu      DTVRELVAAWEAQGVMAREVAVDVASHSPQVDPILDELEEILADLQPMTP
                                          .     :*     : .. * **  ::*:::*:    . .    *

Mflv_0405|M.gilvum_PYR-GCK          TLPLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQFAESVRTVAALGCSVLM
MAB_0939|M.abscessus_ATCC_1997      TLPLVCNRTGAVLTAQTPIDGQYWRRHSRQPVQFAESVRTVAALGCSVLM
MSMEG_0408|M.smegmatis_MC2_155      TLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAESVRTVAALGCSVLM
Mvan_1003|M.vanbaalenii_PYR-1       TRPLVCNRTGAVVTGPGVIDAQYWRRHARQPVQFAESVRTLADLGCSVLM
MMAR_3025|M.marinum_M               TIGIISNLTG-QLAGEDFGSAAYWKRHVRDAVRFADSIRFAQSAGAARFL
MUL_2266|M.ulcerans_Agy99           TIGIISNLTG-QLAGEDFGSAAYWKRHVRDAVRFADSIRFAQSAGAARFL
Mb2074c|M.bovis_AF2122/97           TIGVISNVTG-QLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFL
Rv2048c|M.tuberculosis_H37Rv        TIGVISNVTG-QLAGDDFGSAAYWRRHIRQAVRFADSVRFAQAAGGSRFL
MAV_2450|M.avium_104                VIPIISNLTG-QPAADDFGSPEYWKCHVRDAVRFADSVRFAQSAGATRFL
MLBr_00135|M.leprae_Br4923          QIGLVSNVTG-ELAGPDFGSPQYWGEHVSRAVRFVDSARHLQTLGATHFI
TH_4621|M.thermoresistible__bu      TVPYYS-ATSYDPREKPVCDADYWVDNLRHEVRFAAAVQAALEDGFRVFG
                                         .  *.         .  **  :    *:*. : :     *   : 

Mflv_0405|M.gilvum_PYR-GCK          EIGPQPVLTGAAVQVWPEHLAAPR--AIASLRKGVADRRQIADALAAAYI
MAB_0939|M.abscessus_ATCC_1997      EIGPQPVLTGAAVQVWPEHLAPPR--AIVSLRKGVEDRRQIADALASAYV
MSMEG_0408|M.smegmatis_MC2_155      EIGPQPVLTGAAVQVWPEHMAAPR--AVASLRKGVADRRQIADALASAYV
Mvan_1003|M.vanbaalenii_PYR-1       EIGPQPFLIAAALRVWPESAATPR--AIPSLRKGPDARRQLAEAVAAAYI
MMAR_3025|M.marinum_M               EVGPSSGLTASIEEVLSDAAVTNPVATASALRKDRPEPVSLVSAVAGVFV
MUL_2266|M.ulcerans_Agy99           EVGPSIGLTASIEEVLSDAAVTNPVATASALRKDRPEPVSLVSALAGVFV
Mb2074c|M.bovis_AF2122/97           EVGPSGGLVASIEESLPDVAVT----TMSALRKDRPEPATLTNAVAQGFV
Rv2048c|M.tuberculosis_H37Rv        EVGPSGGLVASIEESLPDVAVT----TMSALRKDRPEPATLTNAVAQGFV
MAV_2450|M.avium_104                EVGPSSGLTAAIEETLADAPVV----TVSALRKDRPEPVALVNAVAQGWV
MLBr_00135|M.leprae_Br4923          ESGPSSGLMGAIEQSLAPAEAV----VVSMMGKDRPELASVLGAAGQLFA
TH_4621|M.thermoresistible__bu      ELSPHPLLTRAVEQTARGLDMPVA--ALPAMRREQEMPHGVRTMVGDLFA
                                    * .*   *  :  .            .   : :       :    .  : 

Mflv_0405|M.gilvum_PYR-GCK          GGHKPDFAALHEQR-GVRLELPTYPFQRRRFWPK---SAGMAIDGRVGAS
MAB_0939|M.abscessus_ATCC_1997      SGHRPNFAALQRHP-RRTVELPTYPFQRRRFWPK---SSGTAIEG--GGG
MSMEG_0408|M.smegmatis_MC2_155      GGHRPDFAAVHRQP-RRPVELPTYPFQRRRFWPK---ASSIAVDG---GT
Mvan_1003|M.vanbaalenii_PYR-1       AGHRLDFTGHDGGP-HRRLPLPTYPFQHRSYWPK---TAGIRSDG----S
MMAR_3025|M.marinum_M               AGTAVDWRAVVGQS--NFVELPTYAFERRRFWLS-GDAVAADAAGLGLQA
MUL_2266|M.ulcerans_Agy99           AGTAVDWRAVVGQS--HFVELPTYAFERRRFWLS-GDAVPADAAGLGLQA
Mb2074c|M.bovis_AF2122/97           TGMDLDWRAVVGEA--QFVELPTYAFQRRRFWLS-GDGVAADAASLGLAA
Rv2048c|M.tuberculosis_H37Rv        TGMDLDWRAVVGEA--QFVELPTYAFQRRRFWLS-GDGVAADAAGLGLAA
MAV_2450|M.avium_104                CGMDVDWRGALGTG--HLVDLPTYAFDRRRFWLS-GDGAASDAAGLGLAA
MLBr_00135|M.leprae_Br4923          TGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPGTDGTASVSGLGLGS
TH_4621|M.thermoresistible__bu      AGAAVDFAALYPSG--RLVDAPLPTWTRRKLVLS--RENGEQQTRGGCTI
                                     *   :: .         :  *  .: :*    .                

Mflv_0405|M.gilvum_PYR-GCK          AGSGILGSGKD-LASGD-SVYTSRLSVKTQPWLSDHVIYGTVVVPGATYA
MAB_0939|M.abscessus_ATCC_1997      LPSGILGRGED-LASGD-SVYISRLSVRSQPWLSDHVIYGTVVVPGATYA
MSMEG_0408|M.smegmatis_MC2_155      AASGILGSGKD-LASGD-TIYTSRLSVKSQPWLADHVIYGTVVVPGATYA
Mvan_1003|M.vanbaalenii_PYR-1       SGSGLLGSAQD-LASGD-IVHTSRLSVKTQPWLSDHVIYGTVVVPGATYA
MMAR_3025|M.marinum_M               GEHALLGAVVELPASGG-VVLTGRLSLAAQGWLADHAVGGVVIFPGAGFV
MUL_2266|M.ulcerans_Agy99           GEHALLGAVVELPASGG-VVLTGRLSLAAQGWLADHAVGGVVIFPGAGFV
Mb2074c|M.bovis_AF2122/97           SEHALLGAVIDLPASGG-VVLTGRLSPSVQGWLADHSVAGVTIFPGAGFV
Rv2048c|M.tuberculosis_H37Rv        SEHALLGAVIDLPASGG-VVLTGRLSPSVQGWLADHSVAGVTIFPGAGFV
MAV_2450|M.avium_104                GDHALLGAVVELPASGG-VLLTGRLSPASQGWLADHAVGGVVLFPGAGFV
MLBr_00135|M.leprae_Br4923          TEHALLGAVVERPDSGG-VVLTGRLSLANQPWLADHVIGGVVLFPGAGFV
TH_4621|M.thermoresistible__bu      TVHPLLGTHVRLPEEPERHVWQADLGTGAQPWLADHQIHTVAALPGAAYC
                                        :**       .    :  . *.   * **:** :  .. .*** : 

Mflv_0405|M.gilvum_PYR-GCK          AMALAAVGTP--AHAKDVFFYEPIILPEKSSREVQLTVHPSVDGE-SKFQ
MAB_0939|M.abscessus_ATCC_1997      AMALAAVGTP--ARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSGSKFQ
MSMEG_0408|M.smegmatis_MC2_155      AMALAAVGTP--ARLKDVFFYEPIILPEKASREVQLTLHPADGGSVLSFQ
Mvan_1003|M.vanbaalenii_PYR-1       AMALAAMPTP--ARVQEVFFYEPIILGDKDSREVQLMLHRTDDADGWTFE
MMAR_3025|M.marinum_M               ELAIRAGDEVGCRVVDELTLAAPLVLPSGGSVAVQVVVGSPDDSGARAVS
MUL_2266|M.ulcerans_Agy99           ELAIRAGDEVGCRVVDELTLAAPLVLPSGGSVAVQVVVGSPDDSGARAVS
Mb2074c|M.bovis_AF2122/97           ELAIRAGDEVGCGVVDELTLAAPLVLPASGSVAVQVVVNGPDESGVRGVS
Rv2048c|M.tuberculosis_H37Rv        ELAIRAGDEVGCGVVDESTLAAPLVLPASGSVAVQVVVNGPDESGVRGVS
MAV_2450|M.avium_104                ELAIRAGDEVGCGIIDELNLAAPLVLPAGGSVAIQVVVDGPDDSGARAVS
MLBr_00135|M.leprae_Br4923          ELVIRAGDEVGCAGVEELVLAAPLVLHPGSGVQVQVVVAAADESSRRAVS
TH_4621|M.thermoresistible__bu      EMALAAAREVIDSDGVEVRDVRFEQMLLLDEQTEVSAVASAVEPGTLEFA
                                     :.: *          :        :           :          . 

Mflv_0405|M.gilvum_PYR-GCK          VHSRPYGERGAE-WALNAEGVVASGVGD---SPAAAGDLEDPVDEAIERL
MAB_0939|M.abscessus_ATCC_1997      VHSRPYGERDVD-WSLNAEGTVVTGIGDDAEPAPEAAEPAEPVDAAIERM
MSMEG_0408|M.smegmatis_MC2_155      IHSRPYGERGAD-WSLNAEGTVDTAGSD---PDAAADEQSDPVDEVIERL
Mvan_1003|M.vanbaalenii_PYR-1       VHSRPYGDRDAD-WSRNASGTVAAGVGD-----AAPDAAADPVDNAIERL
MMAR_3025|M.marinum_M               VYSR--GDAGSD-WVLHAEGSLGSGSPE-----PATDLSTWPPVGAVE--
MUL_2266|M.ulcerans_Agy99           VYSR--GDAGSD-WVLHAEGSLGSGSPE-----PATDLSTWPPVGAVE--
Mb2074c|M.bovis_AF2122/97           VYSR--GDVGTG-WVLHAEGALRAGSAE-----PTADLAMWPPAGAVP--
Rv2048c|M.tuberculosis_H37Rv        VYSR--GDVGTG-WVLHAEGALRAGSAE-----PTADLAMWPPAGAVP--
MAV_2450|M.avium_104                VFSR--ADAGAG-WLLHAEGVLRAGSAQ-----PATDLSAWPPVGAVP--
MLBr_00135|M.leprae_Br4923          VYSR--GDQSHGGWLLNAEGLLEVDAAE-----ATVDLSLWPPEGAES--
TH_4621|M.thermoresistible__bu      VETAKDGEHERR--ATAVLGAADDTEPP-----QAHDIDALLAEHPTR--
                                    : :   .:         . *                              

Mflv_0405|M.gilvum_PYR-GCK          NRMRPQELFETFADLELAWGPTWSGSLKSLWLG--EGEAIGDILVGAELA
MAB_0939|M.abscessus_ATCC_1997      ERMRPMELFEIFADLELAWGPTWSGSLKSLWLG--EGEAIGDVLVGEELA
MSMEG_0408|M.smegmatis_MC2_155      ERMRPQDLFETFADLELAWGPTWSGSLKSLWLG--DGEAVGDILVGAELA
Mvan_1003|M.vanbaalenii_PYR-1       TRTRPQQLFDAFADNDLAWGPAWCSSLRSLWVG--TGEAVGDIAVGAELG
MMAR_3025|M.marinum_M               --VENADGYQQLAERGYGYGPAFRG-LNAMWRR--GDEVFAEVALPADAG
MUL_2266|M.ulcerans_Agy99           --VENADGYQQLAERGYGYGPAFRG-LNAMWRR--GDEVFAEVALPADAG
Mb2074c|M.bovis_AF2122/97           --VEVADGYQQLAERGYGYGPAFRG-LTAMWRR--GDEVFAEVALPADAG
Rv2048c|M.tuberculosis_H37Rv        --VEVADGYQQLAERGYGYGPAFRG-LTAMWRR--GDEVFAEVALPADAG
MAV_2450|M.avium_104                --VDLGDGYEQLAERGYRYGPAFRG-LTSMWRR--GDEIFAEVNLPTDAG
MLBr_00135|M.leprae_Br4923          --VDISDAYPQLAERGYAYGPAFQG-LVAIWRR--GSELFAEVVAPT--G
TH_4621|M.thermoresistible__bu      --IEGDELRQWFDQRGVQFGPAFTGLTAARIPEGTVTSVLAEVGLPGQIR
                                          :    : :    :**:: .   :        . ..::       

Mflv_0405|M.gilvum_PYR-GCK          EQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYGQVSLQE
MAB_0939|M.abscessus_ATCC_1997      EQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLKE
MSMEG_0408|M.smegmatis_MC2_155      EQLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLAE
Mvan_1003|M.vanbaalenii_PYR-1       EHLGREPIHPVLLDLCTGIAGAALLAAAAQTDADPELFLPLRYGRVEVRE
MMAR_3025|M.marinum_M               VSVSGFGIHPVMLDAALHAVILASDGADDFGVPEGSVLVPFAWQGVTLHA
MUL_2266|M.ulcerans_Agy99           VSVSGFGIHPVMLDAALHAVILASDGADDFGVPEGSVLVPFAWQGVTLHA
Mb2074c|M.bovis_AF2122/97           VSVTGFGVHPVLLDAALHAVVLSAESAERG---QGSVLVPFSWQGVSLHA
Rv2048c|M.tuberculosis_H37Rv        VSVTGFGVHPVLLDAALHAVVLSAESAERG---QGSVLVPFSWQGVSLHA
MAV_2450|M.avium_104                VSTTGFGVHPVMLDAALHAVMLASDGDDLP---AGSMLVPFSWQRVSLHA
MLBr_00135|M.leprae_Br4923          VVVDGMGMHPALLDAVLHALGLAIENTQAT----TEMRLPFCWRGVSLHA
TH_4621|M.thermoresistible__bu      SQQAPYGIHPALLDACFQSVAAHPDVQGAG----SGLLLPLGVRRLQAFG
                                           :**.::*                      : :*:    :    

Mflv_0405|M.gilvum_PYR-GCK          KMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVREFTVKRAPRE
MAB_0939|M.abscessus_ATCC_1997      KMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIREFTVKRAPRE
MSMEG_0408|M.smegmatis_MC2_155      KMPRRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPRE
Mvan_1003|M.vanbaalenii_PYR-1       RMPRRFYCRARWQTGGIDSETQVFDLDFLDHDGRNLGGIREFTVKRAPRE
MMAR_3025|M.marinum_M               AGASAVRARIAPAG------PSAVSIELSDGLGLPVLSVASMLARPVTDQ
MUL_2266|M.ulcerans_Agy99           AGASAVRARIAPAG------PSAVSIELSDGLGLPVLSVASMLARPVTDQ
Mb2074c|M.bovis_AF2122/97           AGASAVRARIAPVG------PSAVSIELADGLGLPVLSVASMLARPVTDQ
Rv2048c|M.tuberculosis_H37Rv        AGASAVRARIAPVG------PSAVSIELADGLGLPVLSVASMLARPVTDQ
MAV_2450|M.avium_104                AGAAAVRARIVPVS------PSAVSIELADGLGLPVLSVASMVARPVTDQ
MLBr_00135|M.leprae_Br4923          GGAGRVRARFTSAG------ADAIAVDIADSAGLPVLTVRSLVTRAMTAE
TH_4621|M.thermoresistible__bu      PTRGARYCYARVTDAD--GSKAEADLDVLDEHGNVLLRVQGLLMGGAAAD
                                           .                 ::  *  *  :  :  :     . :

Mflv_0405|M.gilvum_PYR-GCK          ALLRGLGGDA---TRLLYTLGWHEVPVP----ESGDGAAPQGTWLIGGFD
MAB_0939|M.abscessus_ATCC_1997      ALLRGLGGDA---TRLLYTLGWHEVAVPPVAGEGEESAASIGTWLIAGFD
MSMEG_0408|M.smegmatis_MC2_155      ALLRGLGGDA---TRLLYTLGWHEVPPP------PSADDAVGTWLIAGFD
Mvan_1003|M.vanbaalenii_PYR-1       ALLRGLGADA---TRLIYRVGWRETSPP---VRDDGALGPSSTWLVAGLD
MMAR_3025|M.marinum_M               QLRAAVSGAG---PDRLFGVDWTAQPSA-------ELQP----VPVRIWG
MUL_2266|M.ulcerans_Agy99           QLRAAVSGAG---PDRLFGVDWTAQPSA-------ELQP----VPVRIWG
Mb2074c|M.bovis_AF2122/97           QLRAAVSSSG---PDRLFEVTWSPQPSA-------AVEP----LPVCAWG
Rv2048c|M.tuberculosis_H37Rv        QLRAAVSSSG---PDRLFEVTWSPQPSA-------AVEP----LPVCAWG
MAV_2450|M.avium_104                QLLAAVSNSG---PDRLFELIWSAQPST-------AVQP----VSLLNWG
MLBr_00135|M.leprae_Br4923          QLRTAVTAAGGALEQGPMDLVWSPIPLS-------SDGHGGGLPSVVSWA
TH_4621|M.thermoresistible__bu      GDDRDRVLGER-----LLTIEWQRRDLP-------EADSAAGKWLLVSTS
                                                       : *     .                 :    

Mflv_0405|M.gilvum_PYR-GCK          ELAVSVPGCIPADR----------------TNPESLRQLLTDAHGRGLPF
MAB_0939|M.abscessus_ATCC_1997      ELAAKVPGCIPLNRE---------------TDPELLGEVLVAAKERGVPF
MSMEG_0408|M.smegmatis_MC2_155      ELAAKVPGCVPIDRN---------------TDLQVLGEVLSQAHARGAGF
Mvan_1003|M.vanbaalenii_PYR-1       ALADDVPGSIRIGFDRIWDPDRDGRVVLDPADDEHWRRLFALADERRAPV
MMAR_3025|M.marinum_M               AVESEGDDDPG---------------------------------------
MUL_2266|M.ulcerans_Agy99           TVESEGDDDPG---------------------------------------
Mb2074c|M.bovis_AF2122/97           TTEDS---------------------------------------------
Rv2048c|M.tuberculosis_H37Rv        TTEDS---------------------------------------------
MAV_2450|M.avium_104                ATELDATDTDSDSGR-----------------------------------
MLBr_00135|M.leprae_Br4923          DYCAGRGNDTG---------------------------------------
TH_4621|M.thermoresistible__bu      ATADVSATRLSDALKQAG----------AESTSMCWPQQADHADNVDRFR
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          SGVVWRAARSDGDES--DAEVAARLEAEIAELLGAVHTVQ---GGEVKLP
MAB_0939|M.abscessus_ATCC_1997      SGVVWRAAGPGATES--TTESAARLEGEIAHLLSAVHTVQNSAQNGVKLP
MSMEG_0408|M.smegmatis_MC2_155      SGVVWRCATPGRKESGSASAESARLEAEITNLLSAVHAAQ---GPSVKLP
Mvan_1003|M.vanbaalenii_PYR-1       AGVVLGVTGRARPEE-PSADFAARLEAQIRDVLGAVHSLS---ALGAKPA
MMAR_3025|M.marinum_M               ASVVFESVPQAG-------EVVAGVYAATAAVLEVLRSWLS-----RDGA
MUL_2266|M.ulcerans_Agy99           ASVVFESVPQAG-------EVVAGVYAATAAVLEVLRSWLS-----RDGA
Mb2074c|M.bovis_AF2122/97           AAVVFESVPLAG-------DVVAGVYAATSSVLDVLQSWLT-----RDGA
Rv2048c|M.tuberculosis_H37Rv        AAVVFESVPLAG-------DVVAGVYAATSSVLDVLQSWLT-----RDGA
MAV_2450|M.avium_104                FAVLFESAPVAG-------DVVTEVYAATRAVLPVLQSWLA-----RDGA
MLBr_00135|M.leprae_Br4923          -VVVWEFGSASAGAQ-APVDSVAAVYSATHAALQVLQFWFG-----QDRA
TH_4621|M.thermoresistible__bu      AGIADGVTGVVVLTGPKNGNPDDAAARRGSDYVRHLVRITRELAEIDGDA
                                      :                             :  :             .

Mflv_0405|M.gilvum_PYR-GCK          GGLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLVDCDGS
MAB_0939|M.abscessus_ATCC_1997      GGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRAKLVDGDGS
MSMEG_0408|M.smegmatis_MC2_155      GGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGS
Mvan_1003|M.vanbaalenii_PYR-1       AGLWIVTERAVAAEAGEPVDPVQSALWGLGRTLIAEEPGLRCLLVDLDGS
MMAR_3025|M.marinum_M               GQLVITTRGAVALPDEDVTDLAGSAVWGLVRSAQTEHPG-RIVLVDTD-A
MUL_2266|M.ulcerans_Agy99           GQLIITTRGAVALPDEDVTDLAGSAVWGLVRSAQTEHPG-RIVLVDTD-A
Mb2074c|M.bovis_AF2122/97           GVLVVMTRGAVALPGEDVTDLAGAAVWGLVRSAQTEHPG-RIVLVDSD-A
Rv2048c|M.tuberculosis_H37Rv        GVLVVMTRGAVALPGEDVTDLAGAAVWGLVRSAQTEHPG-RIVLVDSD-A
MAV_2450|M.avium_104                GTLVVSTRGAMTLPGEDVTDLAGAAVWGLVRSAQTEHPG-RIVLVDTD-A
MLBr_00135|M.leprae_Br4923          GTLVVLTRGAVGLVGEGISDLAAAAVWGMVRSAQSEHSG-KIVLIDTD-S
TH_4621|M.thermoresistible__bu      PRLFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQIDIADD
                                      * : *. .         :   :.: *: *    *..  :   :*    

Mflv_0405|M.gilvum_PYR-GCK          PQAVQALAALLSTP-VDEPELAVRQGKLLASRLLPWSRSGH----LTVPR
MAB_0939|M.abscessus_ATCC_1997      PEAVQALARLLVTP-VDEPEIAVRQGKLLASRLLPWSRTGH----LTVPR
MSMEG_0408|M.smegmatis_MC2_155      SEAVDLLAALLAAPGIQEPEIAVRQGKLLASRLLPWARSGH----LTLPR
Mvan_1003|M.vanbaalenii_PYR-1       EDAGPALARLLGAP-GDEPELALRQGRLLVPRLLPWSRSGQ----LAIPR
MMAR_3025|M.marinum_M               QLDEHAVAAVLAAG---EPQVLWRNGEVYTARVHGSRAVAG----LLVPP
MUL_2266|M.ulcerans_Agy99           QLDEHAVAAVLAAG---EPQVLWRNGEVYTARVHGSRAVAG----LLVPP
Mb2074c|M.bovis_AF2122/97           PLDDSALAAVVTTG---EPQVLWRRGEVYTARVHGSRAVGG----LLVPP
Rv2048c|M.tuberculosis_H37Rv        PLDDSALAAVVTTG---EPQVLWRRGEVYTARVHGSRAVGG----LLVPP
MAV_2450|M.avium_104                PLDADAVAAVLAVG---EPQTLLRNGTVYTARVLGSRAVGA----LLVPP
MLBr_00135|M.leprae_Br4923          AVD---VAVLADLG---ESQLLVRCNTVHAARLS--PAPQL----LALPV
TH_4621|M.thermoresistible__bu      ADLDRVAVQLLGGG--AEDETAWRDGQWYTARLSLSPLRPEERKQAVVDC
                                           . :       * :   * .   ..*:              :  

Mflv_0405|M.gilvum_PYR-GCK          GGD-YVLAPTERGAIDNLRLTDS-EVPPPAE-GYVQVRVEAAGLNFRDVL
MAB_0939|M.abscessus_ATCC_1997      GSD-YVLAPTERGAIDNLRITEK-EVPAPDE-GYVQVRVEAAGLNFRDVL
MSMEG_0408|M.smegmatis_MC2_155      GGD-FVLAPTERGAIDNLRLTET-DVPEPDE-GYVQVRVEAAGLNFRDVL
Mvan_1003|M.vanbaalenii_PYR-1       GTD-YVLAPTERGVLDNLRVSET-EVTAPPE-GHVQVRVEAAGLNFRDVL
MMAR_3025|M.marinum_M               GDGPWRLGMSTAGTFENLRLEPIPDADAALQPGHVRVALSAMAANFRDVM
MUL_2266|M.ulcerans_Agy99           GDGPWRLGMSTAGTFENLRLEPIPDADAALQPGHVRVALSAMAANFRDVM
Mb2074c|M.bovis_AF2122/97           SDRPWRLAMSTAGTFENLRLELIPDADAPLGPGQVRVAVSAIAANFRDVM
Rv2048c|M.tuberculosis_H37Rv        SDRPWRLAMSTAGTFENLRLELIPDADAPLGPGQVRVAVSAIAANFRDVM
MAV_2450|M.avium_104                EDGPWRLGMSSYGTIENLRLEPIPDADAPLGPGQVRVATSALAANFRDVM
MLBr_00135|M.leprae_Br4923          GESMWRLAADGGGTLEDLVIQPCPEVQAPLQAGHMRVAVAAVGVNFRDVV
TH_4621|M.thermoresistible__bu      ERDGMRLEIRTPGDLETMELAAFDRVPPGPG--QIEVAVTASSINFADVL
                                          *     * :: : :     .        :.*   * . ** **:

Mflv_0405|M.gilvum_PYR-GCK          NVLGLYPGDPG---PIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQGAFA-
MAB_0939|M.abscessus_ATCC_1997      NVLGLYPGDPG---PIGGDFAGIVTQLGEGVTGVEVGQRVYGSMQGAFG-
MSMEG_0408|M.smegmatis_MC2_155      NVLGLYPGDPG---PIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFA-
Mvan_1003|M.vanbaalenii_PYR-1       NALGLYPGDPG---PIGGELAGVVTAPGPDVDGFDVGQRVFGFAVGAFA-
MMAR_3025|M.marinum_M               IALGLYPDPDA---AMGVEGAGVVVETASTDGRFAVGDRVVGLFPEGTG-
MUL_2266|M.ulcerans_Agy99           IALGLYPDPDA---AMGVEGAGVVVETASPDGRFAVGDRVVGLFPEGTG-
Mb2074c|M.bovis_AF2122/97           IALGLYPDPDA---VMGVEACGVVIETSLNKGSFAVGDRVMGLFPEGTG-
Rv2048c|M.tuberculosis_H37Rv        IALGLYPDPDA---VMGVEACGVVIETSLNKGSFAVGDRVMGLFPEGTG-
MAV_2450|M.avium_104                IALGLYPDPDA---VMGIEASGVVIETASQDGRVAVGDRVMGLFPDGTG-
MLBr_00135|M.leprae_Br4923          AALGMYPGQAP---PLGAEGAGVVIEIGPEVTGVAVGDAVMG-FLGGAG-
TH_4621|M.thermoresistible__bu      IAFGRYPTFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSPNGCWS
                                     .:* **        :* : .* *   .       :*: * *    .   

Mflv_0405|M.gilvum_PYR-GCK          SRFNVPGQFLAPIPDGVSAVEAATIPAAALTVRLSF-DWAQVKSGDKVLI
MAB_0939|M.abscessus_ATCC_1997      SRFNVPAQFLAPIPDGISGVEAATIPAAALTVRLSF-DWAQLKPGDKVLI
MSMEG_0408|M.smegmatis_MC2_155      SRFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAF-DWAQLKPGDKVLI
Mvan_1003|M.vanbaalenii_PYR-1       SRVNVPVQFLAPVPEGISAVAAATTPAAVLTAGLAF-DWAALRAGDRVLI
MMAR_3025|M.marinum_M               TIAITDHRLLVKIPAGWSDTAAATTSVVFATAFYALRDLASVQPGQRILV
MUL_2266|M.ulcerans_Agy99           TIAITDHRLLVKIPAGWSDTAAATTSVVFATAFYALRDLASVQPGQRILV
Mb2074c|M.bovis_AF2122/97           TVASTDQRLLVKVPAGWSHTAAATTSVVFATAHYALVDLADVQPGQRVLI
Rv2048c|M.tuberculosis_H37Rv        TVASTDQRLLVKVPAGWSHTAAATTSVVFATAHYALVDLAAARSGQRVLI
MAV_2450|M.avium_104                TVATTDQRLLVKVPAGWSHTAAATASVVFATAYYALVDLADARPGQRVLV
MLBr_00135|M.leprae_Br4923          PLAVVHQQLITQMPQGWSLAEAAAVPVVFLTALFGLADLAGIRAGESVLI
TH_4621|M.thermoresistible__bu      TFVTCDADLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAGEKVLI
                                    .       : . :* *     **: ...  *.  .: * *   .*: :*:

Mflv_0405|M.gilvum_PYR-GCK          HAASGGVGLAAVQMAQQCGAEVYATAST-FKRATLRKLG--VKHVYDSRT
MAB_0939|M.abscessus_ATCC_1997      HAASGGVGLAAIQMAQQFGAEVFATAST-FKRATLRKLG--VKYVYDSRT
MSMEG_0408|M.smegmatis_MC2_155      HAASGGVGLAAIQMAQQSGAEVFATAST-FKRSTLRRLG--VKYVYDSRT
Mvan_1003|M.vanbaalenii_PYR-1       HAASGGVGLAAVQLARQRGATVFATASG-YKRPMLRAMG--VDHVYDSRT
MMAR_3025|M.marinum_M               HAATGGVGMAAVQLARHWGLEVFATASK-GKWDTLRAMGFDEDHIGDSRS
MUL_2266|M.ulcerans_Agy99           HAATGGVGMAAVQLARHWGLEVFATASK-GKWDTLRAMGFDEDHIGDSRS
Mb2074c|M.bovis_AF2122/97           HAGTGGVGMAAVQLARHLGLEVFATASK-GKWDTLRAMGFDDDHISDSRS
Rv2048c|M.tuberculosis_H37Rv        HAGTGGVGMAAVQLARHLGLEVFATASK-GKWDTLRAMGFDDDHISDSRS
MAV_2450|M.avium_104                HAAAGGVGMAAVQLARHLGLEVFATASR-GKWDTLRDMGFDDDHLGDSRG
MLBr_00135|M.leprae_Br4923          HAGTGGVGMAAVQFARHWGVEIFVTASR-GKWDTLRDMGFDDDHIGDSRT
TH_4621|M.thermoresistible__bu      HSATGGVGLAAIAIARSVGAQIYATAGSPARRDLLRDMG--IEHVYDSRS
                                    *:.:****:**: :*:  *  ::.**.   :   ** :*   .:: *** 

Mflv_0405|M.gilvum_PYR-GCK          TDFAEQILADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIAKRDI
MAB_0939|M.abscessus_ATCC_1997      TDFADQILADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRFAEIAKRDI
MSMEG_0408|M.smegmatis_MC2_155      TDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIAKRDI
Mvan_1003|M.vanbaalenii_PYR-1       TDFADQILADTDGAGVDVVLNSLTNDGFVAATVRATARNGRFAEIAKRDI
MMAR_3025|M.marinum_M               LEFEDKFRAATGGRGMDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDI
MUL_2266|M.ulcerans_Agy99           LEFEDKFRAATGGRGMDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDI
Mb2074c|M.bovis_AF2122/97           LEFEDKFRAATGGRGFDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDI
Rv2048c|M.tuberculosis_H37Rv        LEFEDKFRAATGGRGFDVVLDSLAGE-FVDASLRLVAPGGVFLEMGKTDI
MAV_2450|M.avium_104                LDFEDKFRAVTGGAGMDIVLDSLSGD-SVDASLRLVAPGGIFLEMGKTDI
MLBr_00135|M.leprae_Br4923          LEFEEKFLAVTDGRGVDVVLDSLAGD-FVDASLRLLVRGGRFLEMGKTDI
TH_4621|M.thermoresistible__bu      TAFADEIRRDTDGYGVDVVLNSLPGA-AQRAGLELLSFGGRFIEIGKRDI
                                      * :::   *.* *.*:**:**..     * :.     * * *:.* **

Mflv_0405|M.gilvum_PYR-GCK          WTVEQMAAA--RPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRDGAWT
MAB_0939|M.abscessus_ATCC_1997      WTTEQMAQS--RPDIAYEIVALDTVMFQEPDRIRVLLTEVSEGLAKGEWT
MSMEG_0408|M.smegmatis_MC2_155      WSHEQMAEA--RPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMARGEWT
Mvan_1003|M.vanbaalenii_PYR-1       WSPEQMAAA--RPDIDYEVLALDAVMQQDPDRIQLLLADLADSLARGETA
MMAR_3025|M.marinum_M               REAAVVAQQ--HTGVRYRAFDLFEAG---PDHIAQILAELAALFSEDALR
MUL_2266|M.ulcerans_Agy99           REAAVVAQQ--HTGVRYRAFDLFEAG---PDHIAQILAELAALFSEDVLR
Mb2074c|M.bovis_AF2122/97           RDPGVIAQQ--YPGVRYRAFDLFEAG---PDRIAQILAELATLFGDGVLR
Rv2048c|M.tuberculosis_H37Rv        RDPGVIAQQ--YPGVRYRAFDLFEPG---PDRIAQILAELATLFGDGVLR
MAV_2450|M.avium_104                RDPEVVAAE--HPGVRYRAFDLFEAG---PDRIARLLDELAAMFGEDVLR
MLBr_00135|M.leprae_Br4923          RDAQEIAAN--YPGVQYRAFDLSEAG---PVRMQEMLCEVRELFDTQVLH
TH_4621|M.thermoresistible__bu      YGDTRLGLFPFRRNLAFHGVDLGLMADSHPHKIRELLETVYRLTADGVLP
                                         :.      .: :. . *       * ::  :*  :          

Mflv_0405|M.gilvum_PYR-GCK          PLPAEVYPLTEARAAFRRMQQARHIGKIVVQIPNP-LQPQPDRSYLITGG
MAB_0939|M.abscessus_ATCC_1997      PLPAEIYPLTEARTAFRRMQQARHIGKIVCQMPNP-LAPRPDRTYLITGG
MSMEG_0408|M.smegmatis_MC2_155      PLPAEIYPITEARSAFRRMQQARHIGKIVLQVPKP-LQPQQDRSYLITGG
Mvan_1003|M.vanbaalenii_PYR-1       PLPFEAYPLAEATTAFRRMQQARHTGKIILQMPKP-LQPHGDRSYLITGG
MMAR_3025|M.marinum_M               PLPVTTFDVRRAPAALRYLSQARHVGKVVLTMP----DAWAAGTVLITGG
MUL_2266|M.ulcerans_Agy99           PLPVTTFDVRRAPAALRYLSQARHVGKVVLTMP----DAWAAGTVLITGG
Mb2074c|M.bovis_AF2122/97           PLPVTTFDVRRAPAALRYLSQARHTGKVVMLMP----GSWAAGTVLITGG
Rv2048c|M.tuberculosis_H37Rv        PLPVTTFDVRCAPAALRYLSQARHTGKVVMLMP----GSWAAGTVLITGG
MAV_2450|M.avium_104                PLPVTRFDVRRAPAALRYLSQARHVGKVVMTMP----DAWTAGTVLITGA
MLBr_00135|M.leprae_Br4923          RLPVTSWDVRCAPAAFRFMSQARHIGKVVLTMPSALADGLAEGTVLITGA
TH_4621|M.thermoresistible__bu      MPQSTHYPLAEAATAIRVMSAAEHVGKLVLDVP-----------------
                                          : :  * :*:* :. *.* **::  :*                 

Mflv_0405|M.gilvum_PYR-GCK          LGAIG-LHTAGYLAQLGAGDIVLTSRRAPDAAAQQAIADIADRTKARLHV
MAB_0939|M.abscessus_ATCC_1997      LGAIG-LHTAAYLAQLGAGDIVLTSRRAPDTDAQRVIGEITERSKTRIHV
MSMEG_0408|M.smegmatis_MC2_155      LGAIG-LHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHT
Mvan_1003|M.vanbaalenii_PYR-1       LGALG-LHAAAYLAQLGAGDIVLTGRRMPDAATERAISEIAERYHCRIHT
MMAR_3025|M.marinum_M               TGMAGSALARHVVAHHGVRQLVLVSRRGPDAPGAAELAEELSAFGAQVQV
MUL_2266|M.ulcerans_Agy99           TGMAGSALARHVVAHHGVRQLVLVSRRGPDAPGAAELAEELSAFGAQVQV
Mb2074c|M.bovis_AF2122/97           TGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQV
Rv2048c|M.tuberculosis_H37Rv        TGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAELAAAGAQVQV
MAV_2450|M.avium_104                TGMAGSAVARHVVTRHGARNLVLVSRRGLDAPDAAELVAELTAAGAHAEV
MLBr_00135|M.leprae_Br4923          SGAIGGVLARHMVSAYGVRHLVLASRRGDRAEGAVELAAELVGAGAKIQV
TH_4621|M.thermoresistible__bu      --------------HTGRADVVVPPEQASPFRSDGAYIVTGGMGGLGLYL
                                                    *  .:*:  .:                       

Mflv_0405|M.gilvum_PYR-GCK          FTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQQSVERFRT
MAB_0939|M.abscessus_ATCC_1997      FTADVGAESEVAGLLERIRAELPPLAGVAHLAGVLDDALLGQQSVERFRT
MSMEG_0408|M.smegmatis_MC2_155      YAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRT
Mvan_1003|M.vanbaalenii_PYR-1       FAADVGDESAVRDLLERIRTELPPLAGVAHLAGVLDDALLPQQSPERFRT
MMAR_3025|M.marinum_M               VACDAADRAALAKLIADIPVQHP-LSAVIHTAGALDDAVVTSLTPERMET
MUL_2266|M.ulcerans_Agy99           VACDAADRAALAKLIADIPMQHP-LSAVIHTAGALDDAVVTSLTPERIET
Mb2074c|M.bovis_AF2122/97           VACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDV
Rv2048c|M.tuberculosis_H37Rv        VACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVVMSLTPDRVDV
MAV_2450|M.avium_104                VACDAADREALAKVIADIPMQHP-LTGVIHAAGVLDDAVVTSLTPQRIDT
MLBr_00135|M.leprae_Br4923          VACDVADNDAVRGLFAQLSREFPPVRGVIHAAGVLDDGAITSLTPDRVDT
TH_4621|M.thermoresistible__bu      AGEMAAAGAGCIVLNGRSAPSGEALRTIEQLRAAGTEVIVECGXXXRGQP
                                        ..       :      .   :  : :  ..  :  :      *   

Mflv_0405|M.gilvum_PYR-GCK          ALAPKAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSPGQSNYATANAFLD
MAB_0939|M.abscessus_ATCC_1997      TLAPKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGSPGQSNYATANALLD
MSMEG_0408|M.smegmatis_MC2_155      TLAPKAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQANYATANAMLD
Mvan_1003|M.vanbaalenii_PYR-1       TLAPKAFGAWHLHRLTRDTELEFFIVYSSGSSVLGSPGQANYATANAVLD
MMAR_3025|M.marinum_M               VLRAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQGNYAAANSFLD
MUL_2266|M.ulcerans_Agy99           VLRAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQGNYAAANSFLD
Mb2074c|M.bovis_AF2122/97           VLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAAANSFLD
Rv2048c|M.tuberculosis_H37Rv        VLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQANYAAANSFLD
MAV_2450|M.avium_104                VLRAKVDAAWNLHELTRDLDVGAFVMFSSIAGLAGASGQGNYAAGNSFLD
MLBr_00135|M.leprae_Br4923          VLRAKVDAAWNLHEATRDLDLLMFVLCSSIAATVGSPGQGNYSAANAFLD
TH_4621|M.thermoresistible__bu      VEVAVPTELRHADEHPD----------RRGAQLCDEFARGEQGAQRNQHR
                                    .  .        .. .              :   .  .:.: .: .    

Mflv_0405|M.gilvum_PYR-GCK          GLVAQRRAQGLPATGVNFGPWARGGMASSEAAAANIS---AQGLIPLEPS
MAB_0939|M.abscessus_ATCC_1997      GLIAQRRAQGLPATGINFGPWGQGGMASSEAATANIS---AQGLIPLDPS
MSMEG_0408|M.smegmatis_MC2_155      GLVAKRRAQGLVATGINFGPWGQGGMASSEAATANIT---AQGLIPLDPS
Mvan_1003|M.vanbaalenii_PYR-1       GLVAHRKARGLPATGVNWGPWAQGGMATSDAARANLG---AQGLIPLEPT
MMAR_3025|M.marinum_M               GLAVHRQAHGLPAISLGWGLWDQASNMTGGLAAVDFKRFARDGIVAMSSD
MUL_2266|M.ulcerans_Agy99           GLAVHRQAHGLPAISLGWGLWDQASNMTGGLAAVDFKRFARDGIVAMSSD
Mb2074c|M.bovis_AF2122/97           ALAAHRRAHGLPAISLGWGLWDQASAMTSGLATVDFKRFARDGIVAMSSA
Rv2048c|M.tuberculosis_H37Rv        ALAAHRRAHGLPAISLGWGLWDQASAMTGGLATVDFKRFARDGIVAMSSA
MAV_2450|M.avium_104                GLAAHRRAHGLPAISLGWGLWDQASAMTGGLGAADLARFGRDGIVAMSSQ
MLBr_00135|M.leprae_Br4923          GLAAYRQAAGLAGTSLAWGLWEQPGGMNAHLSSRDLARISRSGLAPMNPA
TH_4621|M.thermoresistible__bu      TDAGEGQRDAHPPGAVGHDQPDPGALSDTGLDERGGQFPGVGVQIPVADP
                                          :  .    .:  .     .         .          .:   

Mflv_0405|M.gilvum_PYR-GCK          AALTAMAEVVANGTAQATVLKANWQR-AAKVLGSSRPPILDLVLPSAVGE
MAB_0939|M.abscessus_ATCC_1997      AALAALAEVVANGTGQATILKANWQR-AAKVLGSSRPPILDLVLPSAVGE
MSMEG_0408|M.smegmatis_MC2_155      AALHALAEVIANGSGQATVLKANWQR-AAKVLGSARPPILDLVLPSAAGE
Mvan_1003|M.vanbaalenii_PYR-1       AALNALGEIVAHGIASAVVLKANWQR-AAKLLGATRPPILDHVLPSAVAA
MMAR_3025|M.marinum_M               EALGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMFVDLINAPTRR
MUL_2266|M.ulcerans_Agy99           EALGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMFVDLINAPTRR
Mb2074c|M.bovis_AF2122/97           DALQLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMFVDLINAPTRR
Rv2048c|M.tuberculosis_H37Rv        DALQLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMFVDLINAPTRR
MAV_2450|M.avium_104                EALELMDTALIVDEPFLLPAHIDLAALRVKFDGGTLPPMFVDLINAPTRR
MLBr_00135|M.leprae_Br4923          QALELFDAALVIDHPFMVTALLDRAALDAQAQAGALPPLFSRLVRRSRRR
TH_4621|M.thermoresistible__bu      GVGIDHRGAVRVDSGVPAQQGVDGEVVRHRTLSSVRSGRSSRWTAPGSRC
                                     .       :  .         :      :  ..  .             

Mflv_0405|M.gilvum_PYR-GCK          ITGDS--------ELLKQLQEIPVPQRAGFVTEFLQKEVQNFLRLAQPPA
MAB_0939|M.abscessus_ATCC_1997      VTGDS--------ELLKQLMEIPVPQRAGFVTEFLQREVQNFLRLAQPPA
MSMEG_0408|M.smegmatis_MC2_155      ATGDS--------ELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPA
Mvan_1003|M.vanbaalenii_PYR-1       GPGDS--------ALLKQLQDVPEAQRGSFVTEHLQRELQQILGLAQPPA
MMAR_3025|M.marinum_M               QVDDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIATVLGNSSPDA
MUL_2266|M.ulcerans_Agy99           QVDDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIATVLGNSSPDA
Mb2074c|M.bovis_AF2122/97           QVDDSLAAAKSKSALAHRLHGLPEDEQHAVLLDLVRSHIATVLGSASPEA
Rv2048c|M.tuberculosis_H37Rv        QVDDSLAAAKSKSALLQRLEGLPEDEQHAVLLDLVRSHIATVLGSASPEA
MAV_2450|M.avium_104                QVDDSLAAAKSKSALLQRLEGLPEDEQQAVLLDLVRSNIATVLGSSSPEA
MLBr_00135|M.leprae_Br4923          QIEDPGDATQSKLALVQRLQGLAANRQLELLVGVVCLQAAAVLGRPSPED
TH_4621|M.thermoresistible__bu      G-------------SGRRYGGESCRRTTGPAAGAAARRGRTRRRRRPRRP
                                                    ::    .  .           .            

Mflv_0405|M.gilvum_PYR-GCK          ATS--RFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIGGLAE
MAB_0939|M.abscessus_ATCC_1997      ATS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAE
MSMEG_0408|M.smegmatis_MC2_155      ASS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAE
Mvan_1003|M.vanbaalenii_PYR-1       ATG--RFLELGMDSLMAVELRNRLVGQFGSGFTITATAVFDYPTIGALAE
MMAR_3025|M.marinum_M               IDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPNSAALAG
MUL_2266|M.ulcerans_Agy99           IDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPNSAALAG
Mb2074c|M.bovis_AF2122/97           IDPDRAFQDLGFDSLTAVEMRNRLKSATG--LSLSPTLIFDYPNSAALAG
Rv2048c|M.tuberculosis_H37Rv        IDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIFDYPNSAALAG
MAV_2450|M.avium_104                IHPDRAFQELGFDSLTAVEMRNRLKAATG--LALSPTLIFDYPNSAALAG
MLBr_00135|M.leprae_Br4923          IDPNTKFQDLGFDSLTAVELRNRLKSATG--LTLPPTVIFDHPTPTAVAE
TH_4621|M.thermoresistible__bu      PPPPDRVRHRAGPAHGPVRR------------------------------
                                          . . .  :  .:.                               

Mflv_0405|M.gilvum_PYR-GCK          YLVAQLPDAETP-------------------------------------Q
MAB_0939|M.abscessus_ATCC_1997      YLVGQLPDADAE-------------------------------------S
MSMEG_0408|M.smegmatis_MC2_155      YLVGQLPDAEAP-------------------------------------E
Mvan_1003|M.vanbaalenii_PYR-1       YLAAQTPESTEE-------------------------------------G
MMAR_3025|M.marinum_M               YMHRELVGASPQSDITAEAPGEAELQRVVASIPVKRLRQAGVLELLLALA
MUL_2266|M.ulcerans_Agy99           YMHRELVGASPQSDTTAEAPGEAELQRVVASIPVKRLRQAGVLELLLALA
Mb2074c|M.bovis_AF2122/97           YMRRELLGSSPQ-DTSAVAAGEAELQRIVASIPVKRLRQAGVLDLLLALA
Rv2048c|M.tuberculosis_H37Rv        YMRRELLGSSPQ-DTSAVAAGEAELQRIVASIPVKRLRQAGVLDLLLALA
MAV_2450|M.avium_104                YMYRELVGTSEQ-PTAAAAPGEAEIQRVVGSIPVKRLRQAGVLELLLALA
MLBr_00135|M.leprae_Br4923          YVAQQMLKSRPA--------------------------------------
TH_4621|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0405|M.gilvum_PYR-GCK          AAP-------QSESEPGPDVTE-----------------
MAB_0939|M.abscessus_ATCC_1997      AEAPPAVESAEAESGAGPAAASDAVSELKE---------
MSMEG_0408|M.smegmatis_MC2_155      TA-------------------------------------
Mvan_1003|M.vanbaalenii_PYR-1       TEMKTADPDGQPATVGHADVVLQTS--------------
MMAR_3025|M.marinum_M               NETGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE-
MUL_2266|M.ulcerans_Agy99           NETGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE-
Mb2074c|M.bovis_AF2122/97           NETETSGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE-
Rv2048c|M.tuberculosis_H37Rv        NETETSGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE-
MAV_2450|M.avium_104                NESTGTAQSATPAVTTEKDIADMDLDDLVNAALLDDDDE
MLBr_00135|M.leprae_Br4923          -ESGDETSQAVEPKVEEVSVHA-----------------
TH_4621|M.thermoresistible__bu      ---------------------------------------