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M. marinum M MMAR_2962 (-)

annotation: transcriptional regulatory protein
coordinates: 3576003 - 3579239
length: 1078

DELLLTDTVTLLSADIEDSARLRQTQPTELSAALERLDQILTDAVSAYGGVRAVEQSPGESLVVAFGRAQ
DAVECALQLQQAPLAPIRLCIGIHTGEVAQPRDDGTYVGPTIDRTARLRDLARGGQTLLSAATKDIVINQ
LPEQAWLTDRGLAPLRDLIHFERVAQLCHPNLRNEFPPLCVTKSPAASGLPVHLTSFVGRGRELAEVHGL
VVENRLVTLIGSGGVGKSRLAEQVVAQLAAQFVDGVRYVDLGSITDPAVAPITMARALGLPNQPGRSAMD
TLLHHLGDRQMLLLVDNCEHLLDASAPRLGAMLRDCPGLRLLVTSREPIKVAGEVTWRVPPLAVGDAIAL
FTDRARLAQPDFALTDDNAGTVSQICRRLDTQPLGIELAAARVRTLSLAEISAGLDDKIRLLTGGARTAV
PRQQTLRASLEWSHGLLTDTERVLFRRLGVFVGGFDLQAAQAVAAFGDVHPRDVLGDLSQLVDKSLVVAD
SSNGRTRYRRFEGVGQLALEKLREAGEADIARARHCDHYTAVVAPLDLPARADYDFLLARVEGELENLRA
ASAWLLESSDGESALMLASRLQPLWLVRGRISEGRSWFDAALAGASVLEVSPTVRARALADAAVLTMFVD
VATSLESAAAALAIARELDDPASLVRALTACGLTASFSHHTEAVGQYFAEAASLAEELDDQWGLSQILSW
QSNAAVVAGDAIAARRIGTEGRDLADAIGDRFNSWLCRLSLGYAQLWQGDLTGATTQFGALSEAENLASL
SSKGLGDALAYRGDVDAARTAAEAALERAAESSEYTLGLGYSTVALAALAGGDVETARNASDLAWHKLSV
QPYAAMFWHSFRAEIALACGNVAGAKRCADEAVSVTTGWHRALALTTRARVAMAEGEPEQAERAAYEALT
CAADVGARTCLPDILECLGALAADQGRDREAARVYGAAEGIRQRIGAMRFKIYDAGYQKSVAALHATMST
DEFDTAWAHGAAFSAEEAIDYLQHRRGERKRATSGWAALTRAELNVVRLVGQGLSNKDIAQRLFLSPRTV
QTHLTHVYTKLGFNSRVQLAQQAAQHS*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2962--100% (1078)transcriptional regulatory protein
M. marinum MMMAR_0123-0.050.50% (1095) LuxR family transcriptional regulator
M. marinum MMMAR_3522-2e-9237.60% (609) LuxR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0393-0.056.07% (1088) LuxR/UHPA family transcriptional regulator
M. gilvum PYR-GCKMflv_4504-1e-1225.25% (594) regulatory protein, LuxR
M. tuberculosis H37RvRv0386-0.056.16% (1088) LuxR/UHPA family transcriptional regulator
M. leprae Br4923MLBr_01753-0.047.69% (1084) putative transcriptional regulator
M. abscessus ATCC 19977MAB_3361-5e-1044.44% (81) LuxR family transcriptional regulator
M. avium 104MAV_2362-4e-1229.53% (403) TPR repeat-containing protein
M. smegmatis MC2 155MSMEG_0545-4e-2642.61% (176) transcriptional regulator, LuxR family protein
M. thermoresistible (build 8)TH_3225-1e-0828.52% (298) PUTATIVE regulatory protein, LuxR
M. ulcerans Agy99MUL_2743-2e-9437.93% (609) LuxR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_5928-0.055.42% (1088) regulatory protein, LuxR

CLUSTAL 2.0.9 multiple sequence alignment


Mb0393|M.bovis_AF2122/97            ------MSKLLPRG-------------------------TVTLLLADVEG
Rv0386|M.tuberculosis_H37Rv         ------MSKLLPRG-------------------------TVTLLLADVEG
Mvan_5928|M.vanbaalenii_PYR-1       ------MSELVPTG-------------------------TVTLLLADVQG
MMAR_2962|M.marinum_M               ------MDELLLTD-------------------------TVTLLSADIED
MLBr_01753|M.leprae_Br4923          MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG
MSMEG_0545|M.smegmatis_MC2_155      ------MTEKLSTG-------------------------TKTLLMARVDR
MUL_2743|M.ulcerans_Agy99           ----------------------------------------MTFLFTDVEG
MAB_3361|M.abscessus_ATCC_1997      ----------------------------------------MLRGQAGVGK
TH_3225|M.thermoresistible__bu      -----MSSRDGDVVLHGRAAEIATLRDVMSTARAGSSRVLVLHGEAGVGK
Mflv_4504|M.gilvum_PYR-GCK          -------------------------------------------MRAALPA
MAV_2362|M.avium_104                ------------------------------------------MGREAELR
                                                                                      

Mb0393|M.bovis_AF2122/97            STWLWETHPDDMGAAVARLDKAVSGVIAAHDGVRPVEQGEGDSFVLAFAC
Rv0386|M.tuberculosis_H37Rv         STWLWETHPDDMGAAVARLDKAVSGVIAAHDGVRPVEQGEGDSFVLAFAC
Mvan_5928|M.vanbaalenii_PYR-1       STQLWETQPETMTAAVAQLDRTLTDLVSDHDGVRPVEQGEGDSFVVAFTR
MMAR_2962|M.marinum_M               SARLRQTQPTELSAALERLDQILTDAVSAYGGVRAVEQSPGESLVVAFGR
MLBr_01753|M.leprae_Br4923          LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR
MSMEG_0545|M.smegmatis_MC2_155      AEELWQTELDQTIAAIPWLRASMAHLIALNDGT--LQRDASDSFVAAFDR
MUL_2743|M.ulcerans_Agy99           STRLWESDPDRMRAALAAHDAVLTRTIQTHRGWLFKHTG--DGVCAAFAS
MAB_3361|M.abscessus_ATCC_1997      TALLRYVLGKASGQLIAQASGIQSEMELAFAGLQQFCAPLTKYSGAIPDP
TH_3225|M.thermoresistible__bu      TALLGQLLGDAAGMRCVQVAGVESDMELAYAGLHQLCAPLLDRLDDLPSP
Mflv_4504|M.gilvum_PYR-GCK          AMMNAMSDASPQAADDPQVAGFLCTATSAPTGLIIEGDAGIGKTTLWLSL
MAV_2362|M.avium_104                RSLAALSNAEFHGVALVGDAGVGKSTLARMLAKTVESAGRTVRFALGTQT
                                                                   .                  

Mb0393|M.bovis_AF2122/97            ASDAVAAALDLQRARLAPIRLRIGVHTGEVA--LRDEGNYAGPTINRTAR
Rv0386|M.tuberculosis_H37Rv         ASDAVAAALDLQRARLAPIRLRIGVHTGEVA--LRDEGNYAGPTINRTAR
Mvan_5928|M.vanbaalenii_PYR-1       ASDAVACALALQRAPLAPIRLRIGVHTGEVR--LRDEGNYVGPTINRTAR
MMAR_2962|M.marinum_M               AQDAVECALQLQQAPLAPIRLCIGIHTGEVAQ-PRDDGTYVGPTIDRTAR
MLBr_01753|M.leprae_Br4923          ASDATACALDLQLAPIVPVRFRIALHTGEVQI-SNDDVNNVVFMMVQAAG
MSMEG_0545|M.smegmatis_MC2_155      ASDAVMCALDLQLAPLEPFALCIGVHAVEHTD-SADS--------DGAAR
MUL_2743|M.ulcerans_Agy99           PRSAVDAAVDAQRALELPVRMGLATGEAEPH-----DADYFGAVLNRAAR
MAB_3361|M.abscessus_ATCC_1997      QREALTIAFGTRSGP-PPDRFLIGLAVLSLLA-AAAEHQPVLCVIDDAQW
TH_3225|M.thermoresistible__bu      QRDVLNVAFGRGAGP-APGRFLVGLAVLNLLA-AAGADQPLLCVIDDAQW
Mflv_4504|M.gilvum_PYR-GCK          LQTARMRGFQVLTARVGQAESVMAFAALADLLGAVSDEHFAALPPLQRLA
MAV_2362|M.avium_104                GSAVPLGAFSHAVSLMAVNEPAVMLAAAHNTL---SQDKNLVVVVDDAQL
                                       .   ..    .        :                           

Mb0393|M.bovis_AF2122/97            LRDLAHGGQTVLSGVTESLVIDRLPDKAWLVDLGTHALRDLSRPERVMQL
Rv0386|M.tuberculosis_H37Rv         LRDLAHGGQTVLSGVTESLVIDRLPDKAWLVDLGTHALRDLSRPERVMQL
Mvan_5928|M.vanbaalenii_PYR-1       LRELAHGGQTVLSGTTSDLVADLLPDGGWLSDLGTHRLRDLPRPERVVQL
MMAR_2962|M.marinum_M               LRDLARGGQTLLSAATKDIVINQLPEQAWLTDRGLAPLRDLIHFERVAQL
MLBr_01753|M.leprae_Br4923          LLDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQL
MSMEG_0545|M.smegmatis_MC2_155      LRDIARGGQTLISAAAAALVSARMPAHAALT-----PLRDRVRHEPVYQL
MUL_2743|M.ulcerans_Agy99           VMATGHGGQILLTDSTANLISG-----VDLLDLGSRRLRDLPAPVRVFQV
MAB_3361|M.abscessus_ATCC_1997      LDRVS---LQTLAFVTRRLGSEPVAMLFAVRDGTDSELAGLP-ELTVHGL
TH_3225|M.thermoresistible__bu      LDRVS---LQTLGFVARRLMAEPVAMVFALRDDIHEALVGVP-ALAVPGL
Mflv_4504|M.gilvum_PYR-GCK          LDRVLLRAGADGPATDQRVVAAGFVSLLHILAADAPVLIAIDDVQWLDAS
MAV_2362|M.avium_104                LDPLS----ATLVNQLAAWRSARLIVTIRSGEPVLDAVTALLKERLLLTV
                                    :                                    :        :   

Mb0393|M.bovis_AF2122/97            CHPELRIDFPPLRVANDDVAHGLPVHLTRFVGRGAQITEVHRLVTDNR--
Rv0386|M.tuberculosis_H37Rv         CHPELRIDFPPLRVANDDVAHGLPVHLTRFVGRGAQITEVHRLVTDNR--
Mvan_5928|M.vanbaalenii_PYR-1       CHADLSNEFPPLRAREEIGVQRLPAQLTSFVGRVDDMAQVRGLMDANR--
MMAR_2962|M.marinum_M               CHPNLRNEFPPLCVTKSPAASGLPVHLTSFVGRGRELAEVHGLVVENR--
MLBr_01753|M.leprae_Br4923          CHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKR--
MSMEG_0545|M.smegmatis_MC2_155      NHPGLR--------TEADEVPHLP------YGRVVR--------------
MUL_2743|M.ulcerans_Agy99           RAPGLRTDFPALRAPDTSPG-NLRPALTSFVARAAEIGQVQTALQVHR--
MAB_3361|M.abscessus_ATCC_1997      RAADAGTLLDSVIPGLLDERVRDRIVAETQGNPLALLELPRDMTAEEL--
TH_3225|M.thermoresistible__bu      ADADARTLLEHMFPGAIDANVRDRLVAESRGNPLALLEVPRTYAVGEL--
Mflv_4504|M.gilvum_PYR-GCK          SRTAIEFAVRRLKGAFGVVVTERCVPGDGTTAGWLTLERPDGLIRVSVPP
MAV_2362|M.avium_104                HVDPFTREQTELLAGTVLGGPVDPWVVDELLQRSSGNPLLLRGFLTAG--
                                                                                      

Mb0393|M.bovis_AF2122/97            --LVTLTGAGGVGKTRLAAQLAAQIAGEF-GRAWFVDLAPITDPDLVPVT
Rv0386|M.tuberculosis_H37Rv         --LVTLTGAGGVGKTRLAAQLAAQIAGEF-GRAWFVDLAPITDPDLVPVT
Mvan_5928|M.vanbaalenii_PYR-1       --LVTLTGAGGVGKTRLATQVAVAVVEGYPGGVWYVDLAPITDPALVAIT
MMAR_2962|M.marinum_M               --LVTLIGSGGVGKSRLAEQVVAQLAAQFVDGVRYVDLGSITDPAVAPIT
MLBr_01753|M.leprae_Br4923          --LLTLVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPIT
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           --LVTLTGVGGVGKTRLALEVATRVADEFPDGVWLFELAAVSDPAAVPDA
MAB_3361|M.abscessus_ATCC_1997      --AGGFGWPDGGRLAGQIEQTFLRRVQQLPAHTQTLLLAAATDPLGDVTL
TH_3225|M.thermoresistible__bu      --AGGFVSPGAGSAPSRIEENYVHRIRALPAQTRRLLLIAAAEPIGDSAL
Mflv_4504|M.gilvum_PYR-GCK          MDAGRLHALISHRLGRTLTRPVVLRIAEMSGGNPFYALELAHTHVNSGDS
MAV_2362|M.avium_104                ----RDTGALFRTAEGWQLRGPLRGDRELHDALEYRLQSLSSE-------
                                                                                      

Mb0393|M.bovis_AF2122/97            VAGALGLHDQPGRSTTDTVLRFLGGRPALVVLDNCEHLLDATAALVLALV
Rv0386|M.tuberculosis_H37Rv         VAGALGLHDQPGRSTTDTVLRFLGGRPALVVLDNCEHLLDATAALVLALV
Mvan_5928|M.vanbaalenii_PYR-1       VARALGLPDQPGRSTVDTIVRFIADRRMLVVLDNCEHLLDACATLIDALL
MMAR_2962|M.marinum_M               MARALGLPNQPGRSAMDTLLHHLGDRQMLLLVDNCEHLLDASAPRLGAML
MLBr_01753|M.leprae_Br4923          VL--------------DNLRRCIGDRRMLMVLDNCEYLLDVCANVMTTLL
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           VAAVLGITQQAGKTVTQSVATALERRVRLLVFDNCEHVRDAAADLIEAIL
MAB_3361|M.abscessus_ATCC_1997      LAR---------------AAQQLGIPMHAIAPAEAADLVELSTRVRFRHP
TH_3225|M.thermoresistible__bu      FLR---------------AAALMGIAVDALAPAEAARVIQFGPRMRFFHP
Mflv_4504|M.gilvum_PYR-GCK          PP----------------AAEPPLPATLADVVRRRVGLLDDATRTLLLGV
MAV_2362|M.avium_104                -------------------EREVVEILATAGLLNWDILRDICDAEAVAAL
                                                                                      

Mb0393|M.bovis_AF2122/97            KACRGVRLLATCREPLRVEGEVSYRVPSLSLSD----EAVEMFCYRAQRV
Rv0386|M.tuberculosis_H37Rv         KACRGVRLLATCREPLRVEGEVSYRVPSLSLSD----EAVEMFCYRAQRV
Mvan_5928|M.vanbaalenii_PYR-1       GACPALAMLATSREPIAVAGEQTWRVPPLALDD----DAIELFTDRARRA
MMAR_2962|M.marinum_M               RDCPGLRLLVTSREPIKVAGEVTWRVPPLAVG-----DAIALFTDRARLA
MLBr_01753|M.leprae_Br4923          GACPSLTILATSREPIGVAGEVIWRVSMLSPAD----EAVELFTERAALV
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           AGSTTVRILATSRERLEVPDEQLWSVPSLDVGGGVVSAAGTLFVERAQSV
MAB_3361|M.abscessus_ATCC_1997      LVRSAVYISANPLERRRIHGVLAGATDPGADPD-----------RRAWHR
TH_3225|M.thermoresistible__bu      LMRSAAYRAADPRDRRAVHRALAEATDPGADPD-----------RRAWHA
Mflv_4504|M.gilvum_PYR-GCK          ACVADPTVELLARAHGASTDEITAGLERAEAAG--------IVVLEGNRV
MAV_2362|M.avium_104                ERRGLIRLVTDGSHAVAQLTHPMLGEAATRHAG-----------------
                                                                                      

Mb0393|M.bovis_AF2122/97            RPDFRLTDDNSAAVT-EICKRLDGLPLAIELAAARLRSMTLDEIIDGLRD
Rv0386|M.tuberculosis_H37Rv         RPDFRLTDDNSAAVT-EICKRLDGLPLAIELAAARLRSMTLDEIIDGLRD
Mvan_5928|M.vanbaalenii_PYR-1       RPDFIISADDAAAVS-EICHRLDGMPLAIELAAARVRALSLTEIVDGLHD
MMAR_2962|M.marinum_M               QPDFALTDDNAGTVS-QICRRLDTQPLGIELAAARVRTLSLAEISAGLDD
MLBr_01753|M.leprae_Br4923          QPGFSVTDGNRQIVT-EICQRLDGMPLAIELAAARIRTLSLTEIADGLDD
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           APGFAPTDAQDAAAIGEICRRLDGIPLAIELAASRMASMTPIEVRDRLDH
MAB_3361|M.abscessus_ATCC_1997      AHAAAGTDEAIAWELEQSAGRAQAKGGVLAAAAFLQRATELTADPA----
TH_3225|M.thermoresistible__bu      ANGVTGTDDAVAAELEKSAARAQQRGGIAATATFLERAVVLTADPG----
Mflv_4504|M.gilvum_PYR-GCK          RFTHPLLAGGVYTDAGPTARRAMHRAIASVESHPELRARHLALAASSGDD
MAV_2362|M.avium_104                -MVRTRQLNGKLARALQKHERTGSRHLRLPHLQSRIRLAEFMLHSDMEPD
                                                                                      

Mb0393|M.bovis_AF2122/97            RFALLTGGARTAAHRQQTLWASVDWSYTLLTEPERTLFRRLAVFVGCFFV
Rv0386|M.tuberculosis_H37Rv         RFALLTGGARTAAHRQQTLWASVDWSYTLLTEPERTLFRRLAVFVGCFFV
Mvan_5928|M.vanbaalenii_PYR-1       RFRLLTGGSRTAVRRQQTLRASVDWSHGLLTDPERVLFRRLAVFAGGFDL
MMAR_2962|M.marinum_M               KIRLLTGGARTAVPRQQTLRASLEWSHGLLTDTERVLFRRLGVFVGGFDL
MLBr_01753|M.leprae_Br4923          RFRLLTGGARTAVRRQQTLRASMDWSYALLTESERALFRRLSAISGTFDL
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           RFRLLVG-SRRGLGRHQTLRHAVAWSYDHLSDAEKVLLERCSVFAGGFDL
MAB_3361|M.abscessus_ATCC_1997      ----ARGRRALAAAQSKYDAAAFDAARELLGVADMTPLDPLARARATRLR
TH_3225|M.thermoresistible__bu      ----LRGRRALAAAQAKRDAADSAAAHDLLAIAERAPLSALEWARAVHLR
Mflv_4504|M.gilvum_PYR-GCK          EIFAALDQAADSARARGAPAAAAELMDLALGLGAHDPMRRLKAAENHFLA
MAV_2362|M.avium_104                LDVITEAARDALAMSNVQLGEELARFALDRGGGLPAALVLAEAVSWQGRG
                                                                                      

Mb0393|M.bovis_AF2122/97            DDAQAVACSGDVQR-YQVLDEITLLVDKSLVMADDNSGRTCYRLCETMRH
Rv0386|M.tuberculosis_H37Rv         DDAQAVACSGDVQR-YQVLDEITLLVDKSLVMADDNSGRTCYRLCETMRH
Mvan_5928|M.vanbaalenii_PYR-1       DGAQAITVDGEVHR-YEVVDLLTLLVDKSLLIAENTAGRTRYRLLETVRQ
MMAR_2962|M.marinum_M               QAAQAVAAFGDVHP-RDVLGDLSQLVDKSLVVADSSNGRTRYRRFEGVGQ
MLBr_01753|M.leprae_Br4923          KVAYAVGHDDLEEP-DQVFDRLTMLIDKSLVIVEGRQGGSRYRLLETVRQ
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           QSACAVAGSADTHDDYEVLDLLDALVGKSLLIVDRLSGRSRFSMLETIRE
MAB_3361|M.abscessus_ATCC_1997      AKIAFAESRVGAFGSVTVSEAAIGLVEAARCLENLDDNLARETYLDAVGA
TH_3225|M.thermoresistible__bu      AQLEFARSRAGDAGGPPVGQTAAALLTAAQLLQDVDAPAARESYLEAFAA
Mflv_4504|M.gilvum_PYR-GCK          GDTAKAAAALGEVG---SIEPPILRAMATSLLATVRMYDNEHRQAVDLLR
MAV_2362|M.avium_104                EEAGFVLAHAEPDGDDDWLIARWGCLRAANLFWGCGDAEAARREADTVKK
                                                                                      

Mb0393|M.bovis_AF2122/97            YALEKLSEAGEVDAVFARHRDYYTALAARVDNPGPS-DYSHCLDQAETEI
Rv0386|M.tuberculosis_H37Rv         YALEKLSEAGEVDAVFARHRDYYTALAARVDNPGPS-DYSHCLDQAETEI
Mvan_5928|M.vanbaalenii_PYR-1       YAQEKLGESGEADTLRARHRDHYTARAAELDAPSVA-GHERRLNQTDIEM
MMAR_2962|M.marinum_M               LALEKLREAGEADIARARHCDHYTAVVAPLDLPARA-DYDFLLARVEGEL
MLBr_01753|M.leprae_Br4923          YAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDI-DHEQLVEQVETEL
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           FAEEQLVTRGQALAARTAHARHFAQRLPDVAAVWDSPRQPEAYTWLTAEL
MAB_3361|M.abscessus_ATCC_1997      AMYGGRLCPRGGAVEVAEPARLAPAGAQP-----------------ARPS
TH_3225|M.thermoresistible__bu      LMYAGRLAPSGALLEAADAVQAAFARAPEG----------------SRAV
Mflv_4504|M.gilvum_PYR-GCK          SALDDAADNVPVQVQVLLRLSFALNSIGELDDARRY-----ARDAVKLAE
MAV_2362|M.avium_104                RVSSEAG--LHLIDALELSMAFFRGDVETTTELGPG----------LCES
                                                                                      

Mb0393|M.bovis_AF2122/97            DNLRAAFVWNRENSDTEGALALASSLLRVWMTRG-RIQEGRAWFDSILAD
Rv0386|M.tuberculosis_H37Rv         DNLRAAFVWNRENSDTEGALALASSLLRVWMTRG-RIQEGRAWFDSILAD
Mvan_5928|M.vanbaalenii_PYR-1       DNLRAAFAWSRENANTDHSLLLASSLHPLWRARG-RLQEGQAWFDAALTD
MMAR_2962|M.marinum_M               ENLRAASAWLLESSDGESALMLASRLQPLWLVRG-RISEGRSWFDAALAG
MLBr_01753|M.leprae_Br4923          DNLRSAFAWSRETGDIAGALQLASSLQPIWFGRG-HMYEGLAWFDSIFEH
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           ANLRLAFRWTADNNDLDDAASIATWVGFLGFLVN-RFEP-LTWVEEAIER
MAB_3361|M.abscessus_ATCC_1997      DLLLDGLARRITHGAAASAQTLGEALTLIRCEAD-RPANTS-WMEQAFPI
TH_3225|M.thermoresistible__bu      DAFCQGMTQRIVGGISAAAAPLRVALTAMCELARSRPAEVVHWLVPAFPV
Mflv_4504|M.gilvum_PYR-GCK          ELGFPGATSAALAWAVHVDFQCGRGLDETALARAMKLYDSTFDVPIIFRA
MAV_2362|M.avium_104                DAVPMATTWAAVPTCAALAATGRYSEVGRIADIGVRAAMSCGMGLHRFNI
                                                                                      

Mb0393|M.bovis_AF2122/97            ENARHLEVAAAVRARALADKALLDIFVDAAAG-----MEQAQQALVIARE
Rv0386|M.tuberculosis_H37Rv         ENARHLEVAAAVRARALADKALLDIFVDAAAG-----MEQAQQALVIARE
Mvan_5928|M.vanbaalenii_PYR-1       YEARPGEADPAVYARALADRAFMDGHVGITDR-----LDQAQKALAMARD
MMAR_2962|M.marinum_M               --ASVLEVSPTVRARALADAAVLTMFVDVATS-----LESAAAALAIARE
MLBr_01753|M.leprae_Br4923          KNIEHLVAPKEVLARAVANKVMLHAILASSPPDGSDLVTQAQQALTMARE
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           AVDHPKLAFLHVLASQCYTTGRVQEAIR----------------------
MAB_3361|M.abscessus_ATCC_1997      ALESATHEVWDDDMWHHLA-------------------------------
TH_3225|M.thermoresistible__bu      LQESAGHELWDENLVDALS-------------------------------
Mflv_4504|M.gilvum_PYR-GCK          PFVHALAMSWTGRLEQAHQ-------------------------------
MAV_2362|M.avium_104                GISEIIAATDAGDDRAAER-------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            VDEPALLSRALTACGLIAVAVARADAAASYFAEAIDLARAVDDRWRLAQI
Rv0386|M.tuberculosis_H37Rv         VDEPALLSRALTACGLIAVAVARADAAASYFAEAIDLARAVDDRWRLAQI
Mvan_5928|M.vanbaalenii_PYR-1       IDDPALLVRALTACG--GLAAYNADVARPLLAEAVDLARSMGDKWMLAET
MMAR_2962|M.marinum_M               LDDPASLVRALTACGLTASFSHHTEAVGQYFAEAASLAEELDDQWGLSQI
MLBr_01753|M.leprae_Br4923          IGDSAVLARALTACG--FSSGYDTEVARPYFAEAVELARTQGDKWTLSQI
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           ------------------------------YADEAARLLATDRYEVPFGI
MAB_3361|M.abscessus_ATCC_1997      -------------------------------TRAVHIAREVGALSLLPAA
TH_3225|M.thermoresistible__bu      -------------------------------EAVVRQARDAGALAGLPQA
Mflv_4504|M.gilvum_PYR-GCK          -----------------------------ELTAVRGVCLERGAESDMMAI
MAV_2362|M.avium_104                -------------------------------IYKRYAAMAEGLPGAEAMV
                                                                                      

Mb0393|M.bovis_AF2122/97            LTFQAVDAVVAG-DPVAARPAAQEARELAAAIGDHSNALWCRWCLGYAQL
Rv0386|M.tuberculosis_H37Rv         LTFQAVDAVVAG-DPVAARPAAQEARELAAAIGDHSNALWCRWCLGYAQL
Mvan_5928|M.vanbaalenii_PYR-1       LAWQAYAALMGGGDPVAARTAGEEARELADEMGDGFVSRICGWLLGIAHH
MMAR_2962|M.marinum_M               LSWQSNAAVVAG-DAIAARRIGTEGRDLADAIGDRFNSWLCRLSLGYAQL
MLBr_01753|M.leprae_Br4923          RLWGVVGFCVSG-DPVALRAAAEAADDLAQEIGDRFVSLQCRLLLSIAQL
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           EGWPSGACTSSG--------------------------------------
MAB_3361|M.abscessus_ATCC_1997      LIYRAGMHVHAG--------------------------------------
TH_3225|M.thermoresistible__bu      LVYRAGVHLLFG--------------------------------------
Mflv_4504|M.gilvum_PYR-GCK          AGFLAINHLWRG--------------------------------------
MAV_2362|M.avium_104                DAMLGVVRLARG--------------------------------------
                                                                                      

Mb0393|M.bovis_AF2122/97            MRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAFALAYQGELSAARA
Rv0386|M.tuberculosis_H37Rv         MRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAFALAYQGELSAARA
Mvan_5928|M.vanbaalenii_PYR-1       FQGDLDAALALADGVVSESDVAHDTLNGCCGELVLAHSLAQRGDTDAARA
MMAR_2962|M.marinum_M               WQGDLTGATTQFGALSEAENLASLSSK------GLGDALAYRGDVDAART
MLBr_01753|M.leprae_Br4923          WQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQTRALVHR-DVSAALV
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           -------------------------------------------HPEQSVE
MAB_3361|M.abscessus_ATCC_1997      ----------------------------------------ELDAAAELVQ
TH_3225|M.thermoresistible__bu      ----------------------------------------EFGLADTLLT
Mflv_4504|M.gilvum_PYR-GCK          -------------------------------------QITDAEAEAAEAV
MAV_2362|M.avium_104                -------------------------------------------------E
                                                                                      

Mb0393|M.bovis_AF2122/97            AADAAL-EAAELGEYFAGMGYSALTTAALAAGDVQTAQHASEAAWRNLSL
Rv0386|M.tuberculosis_H37Rv         AADAAL-EAAELGEYFAGMGYSALTTAALAAGDVQTAQHASEAAWRNLSL
Mvan_5928|M.vanbaalenii_PYR-1       AAQVSLNVAVEVSPVHAGLAHAALAVANLAAGDVTAAEAASDSATRSFGP
MMAR_2962|M.marinum_M               AAEAALERAAESSEYTLGLGYSTVALAALAGGDVETARNASDLAWHKLSV
MLBr_01753|M.leprae_Br4923          TAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAVEASEACRPHLGA
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           LCRTQLALGHDTHTLTLGCLVLALTIKGQCDEAEQLADALIESAEATRNP
MAB_3361|M.abscessus_ATCC_1997      EADAISAATGH-APIRYHSLILAAWRGSEPTAIRLIDEAMRDGAARGEGR
TH_3225|M.thermoresistible__bu      EAESITAATDHRGPVRYHRLIIAAWRGDAVEAARLIEAAAADGEARGEGR
Mflv_4504|M.gilvum_PYR-GCK          ERAEQLGGDDVLIIPMTVRGAIAAYAGRVDDARADARWVLAAVRNRKASH
MAV_2362|M.avium_104                FPAACAAFTRSISLFAKGFPSPWLVVVGAFQAQAEGARGDSTAAAAALWR
                                                                                      

Mb0393|M.bovis_AF2122/97            ALPLSAAVQRAFNAQAALAGGDLSAARR----WCDDAVQSMTGHHLAMAL
Rv0386|M.tuberculosis_H37Rv         ALPLSAAVQRAFNAQAALAGGDLSAARR----WCDDAVQSMTGHHLAMAL
Mvan_5928|M.vanbaalenii_PYR-1       SE-VAGIQDPNVAAQIACTRGDLDTARS----LVDGAVSITRGVHRASAL
MMAR_2962|M.marinum_M               QP-YAAMFWHSFRAEIALACGNVAGAKR----CADEAVSVTTGWHRALAL
MLBr_01753|M.leprae_Br4923          DHGLVAIH-LELMAAVALARGDVIVARR----LADNSVSATTGWHQMAAL
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           AALCYALLAYGFTFRDTNPASALAAMRR----GLRIAQDTGNRNSETHLA
MAB_3361|M.abscessus_ATCC_1997      LLGAMGYAAGVLNNSLGRYELAFMAARR----ACEHEDLGLYSWCLIELI
TH_3225|M.thermoresistible__bu      LMGLTGYAAALLYNGIGRYREALAAART----TCEYEDLGFYSWCLHELV
Mflv_4504|M.gilvum_PYR-GCK          IADWPGMTLCFLEESLGNHREALAALDDSFIAAGPPTTELMYAWHLPDAI
MAV_2362|M.avium_104                ADRAYGPHAAVFLPELELARAWERAAAG------DTQAATTHATQAAEIA
                                                                                      

Mb0393|M.bovis_AF2122/97            ATRARIAVAEGKREEAERDAHKALACAAESGAHLDLPDVLECLAGL----
Rv0386|M.tuberculosis_H37Rv         ATRARIAVAEGKREEAERDAHKALACAAESGAHLDLPDVLECLAGL----
Mvan_5928|M.vanbaalenii_PYR-1       TTRARIAIAQGDPEQAERNAHDALSLAAGVGARLEVPDTLECLARV----
MMAR_2962|M.marinum_M               TTRARVAMAEGEPEQAERAAYEALTCAADVGARTCLPDILECLGAL----
MLBr_01753|M.leprae_Br4923          TTRARIAMAQGEPELARADIHAALACGADIQASLGISDSMELLAEL----
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           AVLCRVEAKYGDPLSALDHFTLAIHNHHEAGNTTLISTPLAVLAAF----
MAB_3361|M.abscessus_ATCC_1997      EAAVRCGEHDTAVKAFGQLEERALAAQSDWSQGMVARSRALITVGH----
TH_3225|M.thermoresistible__bu      EAAARVGETDTAHRALGDIEERAGASGTPWGLGALAGARALLADGD----
Mflv_4504|M.gilvum_PYR-GCK          EAMVGVGRLDDAEILTAALERNGVEHDRRWMRAVGARCRAMLLAAHGDVA
MAV_2362|M.avium_104                RAAGMHAAEMRTRHAAVRFGDRSQTARLERLARILDTPLAEAAADH----
                                                                                      

Mb0393|M.bovis_AF2122/97            ASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYVQSVTALRDAMGEK
Rv0386|M.tuberculosis_H37Rv         ASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYVQSVTALRDAMGEK
Mvan_5928|M.vanbaalenii_PYR-1       VGDGGSHHEAARLCGAAEAIRGRTGAVRFRIYDADHETTVTTLRDALGDK
MMAR_2962|M.marinum_M               AADQGRDREAARVYGAAEGIRQRIGAMRFKIYDAGYQKSVAALHATMSTD
MLBr_01753|M.leprae_Br4923          ISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLRGAMGCK
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           FDRLGRYEAAATIAGFAFHPITEASFP-------ELRTTISHLRDALGDH
MAB_3361|M.abscessus_ATCC_1997      DAEPHYREAIQRLTNTRISAHLARAHLIYGEWLRRCNRRSDARTELTAAH
TH_3225|M.thermoresistible__bu      EADRLFREALDHLSRSRVVVHRARVHLTYGEWLRREHRRGEARRELNEAH
Mflv_4504|M.gilvum_PYR-GCK          AAEQMAHRAISEHDHLPMPFERARTRLLLGQLQRRLRQKATAAKNLTDAL
MAV_2362|M.avium_104                --ARGLTQRDGDLLDAAAQQFADLGALACAADAAAQAAGEHARRGDRGKK
                                                                                      

Mb0393|M.bovis_AF2122/97            DFAAAWAEGAALSIKETIAYAQRGHSWRKRPATGWESLTPTEIDVVRLVG
Rv0386|M.tuberculosis_H37Rv         DFDAAWAEGAALSIKETIAYAQRGHSWRKRPATGWESLTPTEIDVVRLVG
Mvan_5928|M.vanbaalenii_PYR-1       AFEAAWTEGSATSITEAIAYAQRGRGERKRPSSGWASLTPTELDVVGLVS
MMAR_2962|M.marinum_M               EFDTAWAHGAAFSAEEAIDYLQHRRGERKRATSGWAALTRAELNVVRLVG
MLBr_01753|M.leprae_Br4923          DFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNVIRLVS
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           AYESFSQSGAAMTTAAMATYAYHQIDHARTEFQAR---------------
MAB_3361|M.abscessus_ATCC_1997      GSFVNMG-TAAFAERAERELRATGAKVRKRSASSEKALTAQEAQIARMAG
TH_3225|M.thermoresistible__bu      GMFTRMG-AQGFAERSRRELIAVGEKVRRQPLTSGDELTAQEAQIAGLAA
Mflv_4504|M.gilvum_PYR-GCK          HTFEQLG--------TPLWAQRARSELARAVVAPAEGLTPSEQKVAEMAA
MAV_2362|M.avium_104                --FESSAWAHALASRYELHTPAVEAAARPLPFSGR------ERQIVNLVA
                                                                                      

Mb0393|M.bovis_AF2122/97            EGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT----
Rv0386|M.tuberculosis_H37Rv         EGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT----
Mvan_5928|M.vanbaalenii_PYR-1       EGLSNKDIAARLFVSPRTVQTHLTHVYTKLCLASRVQLAQEAARHT----
MMAR_2962|M.marinum_M               QGLSNKDIAQRLFLSPRTVQTHLTHVYTKLGFNSRVQLAQQAAQHS----
MLBr_01753|M.leprae_Br4923          EGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN----
MSMEG_0545|M.smegmatis_MC2_155      --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997      QGLTNQEIAAQLFISSHTVEWHLRKVFAKRGITSRRQLRSGR--------
TH_3225|M.thermoresistible__bu      DGLTNQEIGAQLFLSVHTVEWHLRKVFVKLGITSRRQLRAAPRVTATW--
Mflv_4504|M.gilvum_PYR-GCK          AGATNKDIAAAMFISSKTVEHNLTRIYRKLGISSRAELGRRMDQPGL---
MAV_2362|M.avium_104                AGLSNREIADRLVISVRTVEGHLYRLFTKLGINSREQLTLLVAREPRGRR
                                                                                      

Mb0393|M.bovis_AF2122/97            ---------------------
Rv0386|M.tuberculosis_H37Rv         ---------------------
Mvan_5928|M.vanbaalenii_PYR-1       ---------------------
MMAR_2962|M.marinum_M               ---------------------
MLBr_01753|M.leprae_Br4923          ---------------------
MSMEG_0545|M.smegmatis_MC2_155      ---------------------
MUL_2743|M.ulcerans_Agy99           ---------------------
MAB_3361|M.abscessus_ATCC_1997      ---------------------
TH_3225|M.thermoresistible__bu      ---------------------
Mflv_4504|M.gilvum_PYR-GCK          ---------------------
MAV_2362|M.avium_104                ELLGHSNPSLGDQDDVHPHAG