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DELLLTDTVTLLSADIEDSARLRQTQPTELSAALERLDQILTDAVSAYGGVRAVEQSPGESLVVAFGRAQ DAVECALQLQQAPLAPIRLCIGIHTGEVAQPRDDGTYVGPTIDRTARLRDLARGGQTLLSAATKDIVINQ LPEQAWLTDRGLAPLRDLIHFERVAQLCHPNLRNEFPPLCVTKSPAASGLPVHLTSFVGRGRELAEVHGL VVENRLVTLIGSGGVGKSRLAEQVVAQLAAQFVDGVRYVDLGSITDPAVAPITMARALGLPNQPGRSAMD TLLHHLGDRQMLLLVDNCEHLLDASAPRLGAMLRDCPGLRLLVTSREPIKVAGEVTWRVPPLAVGDAIAL FTDRARLAQPDFALTDDNAGTVSQICRRLDTQPLGIELAAARVRTLSLAEISAGLDDKIRLLTGGARTAV PRQQTLRASLEWSHGLLTDTERVLFRRLGVFVGGFDLQAAQAVAAFGDVHPRDVLGDLSQLVDKSLVVAD SSNGRTRYRRFEGVGQLALEKLREAGEADIARARHCDHYTAVVAPLDLPARADYDFLLARVEGELENLRA ASAWLLESSDGESALMLASRLQPLWLVRGRISEGRSWFDAALAGASVLEVSPTVRARALADAAVLTMFVD VATSLESAAAALAIARELDDPASLVRALTACGLTASFSHHTEAVGQYFAEAASLAEELDDQWGLSQILSW QSNAAVVAGDAIAARRIGTEGRDLADAIGDRFNSWLCRLSLGYAQLWQGDLTGATTQFGALSEAENLASL SSKGLGDALAYRGDVDAARTAAEAALERAAESSEYTLGLGYSTVALAALAGGDVETARNASDLAWHKLSV QPYAAMFWHSFRAEIALACGNVAGAKRCADEAVSVTTGWHRALALTTRARVAMAEGEPEQAERAAYEALT CAADVGARTCLPDILECLGALAADQGRDREAARVYGAAEGIRQRIGAMRFKIYDAGYQKSVAALHATMST DEFDTAWAHGAAFSAEEAIDYLQHRRGERKRATSGWAALTRAELNVVRLVGQGLSNKDIAQRLFLSPRTV QTHLTHVYTKLGFNSRVQLAQQAAQHS*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2962 | - | - | 100% (1078) | transcriptional regulatory protein |
M. marinum M | MMAR_0123 | - | 0.0 | 50.50% (1095) | LuxR family transcriptional regulator |
M. marinum M | MMAR_3522 | - | 2e-92 | 37.60% (609) | LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0393 | - | 0.0 | 56.07% (1088) | LuxR/UHPA family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_4504 | - | 1e-12 | 25.25% (594) | regulatory protein, LuxR |
M. tuberculosis H37Rv | Rv0386 | - | 0.0 | 56.16% (1088) | LuxR/UHPA family transcriptional regulator |
M. leprae Br4923 | MLBr_01753 | - | 0.0 | 47.69% (1084) | putative transcriptional regulator |
M. abscessus ATCC 19977 | MAB_3361 | - | 5e-10 | 44.44% (81) | LuxR family transcriptional regulator |
M. avium 104 | MAV_2362 | - | 4e-12 | 29.53% (403) | TPR repeat-containing protein |
M. smegmatis MC2 155 | MSMEG_0545 | - | 4e-26 | 42.61% (176) | transcriptional regulator, LuxR family protein |
M. thermoresistible (build 8) | TH_3225 | - | 1e-08 | 28.52% (298) | PUTATIVE regulatory protein, LuxR |
M. ulcerans Agy99 | MUL_2743 | - | 2e-94 | 37.93% (609) | LuxR family transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_5928 | - | 0.0 | 55.42% (1088) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment Mb0393|M.bovis_AF2122/97 ------MSKLLPRG-------------------------TVTLLLADVEG Rv0386|M.tuberculosis_H37Rv ------MSKLLPRG-------------------------TVTLLLADVEG Mvan_5928|M.vanbaalenii_PYR-1 ------MSELVPTG-------------------------TVTLLLADVQG MMAR_2962|M.marinum_M ------MDELLLTD-------------------------TVTLLSADIED MLBr_01753|M.leprae_Br4923 MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTDLHRGCTVTLFLGDVEG MSMEG_0545|M.smegmatis_MC2_155 ------MTEKLSTG-------------------------TKTLLMARVDR MUL_2743|M.ulcerans_Agy99 ----------------------------------------MTFLFTDVEG MAB_3361|M.abscessus_ATCC_1997 ----------------------------------------MLRGQAGVGK TH_3225|M.thermoresistible__bu -----MSSRDGDVVLHGRAAEIATLRDVMSTARAGSSRVLVLHGEAGVGK Mflv_4504|M.gilvum_PYR-GCK -------------------------------------------MRAALPA MAV_2362|M.avium_104 ------------------------------------------MGREAELR Mb0393|M.bovis_AF2122/97 STWLWETHPDDMGAAVARLDKAVSGVIAAHDGVRPVEQGEGDSFVLAFAC Rv0386|M.tuberculosis_H37Rv STWLWETHPDDMGAAVARLDKAVSGVIAAHDGVRPVEQGEGDSFVLAFAC Mvan_5928|M.vanbaalenii_PYR-1 STQLWETQPETMTAAVAQLDRTLTDLVSDHDGVRPVEQGEGDSFVVAFTR MMAR_2962|M.marinum_M SARLRQTQPTELSAALERLDQILTDAVSAYGGVRAVEQSPGESLVVAFGR MLBr_01753|M.leprae_Br4923 LAELSETQPDEAADAIARLDCVVSEAVAAHGGVQQVVQGVRGNFLATFAR MSMEG_0545|M.smegmatis_MC2_155 AEELWQTELDQTIAAIPWLRASMAHLIALNDGT--LQRDASDSFVAAFDR MUL_2743|M.ulcerans_Agy99 STRLWESDPDRMRAALAAHDAVLTRTIQTHRGWLFKHTG--DGVCAAFAS MAB_3361|M.abscessus_ATCC_1997 TALLRYVLGKASGQLIAQASGIQSEMELAFAGLQQFCAPLTKYSGAIPDP TH_3225|M.thermoresistible__bu TALLGQLLGDAAGMRCVQVAGVESDMELAYAGLHQLCAPLLDRLDDLPSP Mflv_4504|M.gilvum_PYR-GCK AMMNAMSDASPQAADDPQVAGFLCTATSAPTGLIIEGDAGIGKTTLWLSL MAV_2362|M.avium_104 RSLAALSNAEFHGVALVGDAGVGKSTLARMLAKTVESAGRTVRFALGTQT . Mb0393|M.bovis_AF2122/97 ASDAVAAALDLQRARLAPIRLRIGVHTGEVA--LRDEGNYAGPTINRTAR Rv0386|M.tuberculosis_H37Rv ASDAVAAALDLQRARLAPIRLRIGVHTGEVA--LRDEGNYAGPTINRTAR Mvan_5928|M.vanbaalenii_PYR-1 ASDAVACALALQRAPLAPIRLRIGVHTGEVR--LRDEGNYVGPTINRTAR MMAR_2962|M.marinum_M AQDAVECALQLQQAPLAPIRLCIGIHTGEVAQ-PRDDGTYVGPTIDRTAR MLBr_01753|M.leprae_Br4923 ASDATACALDLQLAPIVPVRFRIALHTGEVQI-SNDDVNNVVFMMVQAAG MSMEG_0545|M.smegmatis_MC2_155 ASDAVMCALDLQLAPLEPFALCIGVHAVEHTD-SADS--------DGAAR MUL_2743|M.ulcerans_Agy99 PRSAVDAAVDAQRALELPVRMGLATGEAEPH-----DADYFGAVLNRAAR MAB_3361|M.abscessus_ATCC_1997 QREALTIAFGTRSGP-PPDRFLIGLAVLSLLA-AAAEHQPVLCVIDDAQW TH_3225|M.thermoresistible__bu QRDVLNVAFGRGAGP-APGRFLVGLAVLNLLA-AAGADQPLLCVIDDAQW Mflv_4504|M.gilvum_PYR-GCK LQTARMRGFQVLTARVGQAESVMAFAALADLLGAVSDEHFAALPPLQRLA MAV_2362|M.avium_104 GSAVPLGAFSHAVSLMAVNEPAVMLAAAHNTL---SQDKNLVVVVDDAQL . .. . : Mb0393|M.bovis_AF2122/97 LRDLAHGGQTVLSGVTESLVIDRLPDKAWLVDLGTHALRDLSRPERVMQL Rv0386|M.tuberculosis_H37Rv LRDLAHGGQTVLSGVTESLVIDRLPDKAWLVDLGTHALRDLSRPERVMQL Mvan_5928|M.vanbaalenii_PYR-1 LRELAHGGQTVLSGTTSDLVADLLPDGGWLSDLGTHRLRDLPRPERVVQL MMAR_2962|M.marinum_M LRDLARGGQTLLSAATKDIVINQLPEQAWLTDRGLAPLRDLIHFERVAQL MLBr_01753|M.leprae_Br4923 LLDLACGGQTVLSSITGDLVVDGLPADTWLVDLGSHLLRDLARPVRVMQL MSMEG_0545|M.smegmatis_MC2_155 LRDIARGGQTLISAAAAALVSARMPAHAALT-----PLRDRVRHEPVYQL MUL_2743|M.ulcerans_Agy99 VMATGHGGQILLTDSTANLISG-----VDLLDLGSRRLRDLPAPVRVFQV MAB_3361|M.abscessus_ATCC_1997 LDRVS---LQTLAFVTRRLGSEPVAMLFAVRDGTDSELAGLP-ELTVHGL TH_3225|M.thermoresistible__bu LDRVS---LQTLGFVARRLMAEPVAMVFALRDDIHEALVGVP-ALAVPGL Mflv_4504|M.gilvum_PYR-GCK LDRVLLRAGADGPATDQRVVAAGFVSLLHILAADAPVLIAIDDVQWLDAS MAV_2362|M.avium_104 LDPLS----ATLVNQLAAWRSARLIVTIRSGEPVLDAVTALLKERLLLTV : : : Mb0393|M.bovis_AF2122/97 CHPELRIDFPPLRVANDDVAHGLPVHLTRFVGRGAQITEVHRLVTDNR-- Rv0386|M.tuberculosis_H37Rv CHPELRIDFPPLRVANDDVAHGLPVHLTRFVGRGAQITEVHRLVTDNR-- Mvan_5928|M.vanbaalenii_PYR-1 CHADLSNEFPPLRAREEIGVQRLPAQLTSFVGRVDDMAQVRGLMDANR-- MMAR_2962|M.marinum_M CHPNLRNEFPPLCVTKSPAASGLPVHLTSFVGRGRELAEVHGLVVENR-- MLBr_01753|M.leprae_Br4923 CHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAAQIKELQELLTEKR-- MSMEG_0545|M.smegmatis_MC2_155 NHPGLR--------TEADEVPHLP------YGRVVR-------------- MUL_2743|M.ulcerans_Agy99 RAPGLRTDFPALRAPDTSPG-NLRPALTSFVARAAEIGQVQTALQVHR-- MAB_3361|M.abscessus_ATCC_1997 RAADAGTLLDSVIPGLLDERVRDRIVAETQGNPLALLELPRDMTAEEL-- TH_3225|M.thermoresistible__bu ADADARTLLEHMFPGAIDANVRDRLVAESRGNPLALLEVPRTYAVGEL-- Mflv_4504|M.gilvum_PYR-GCK SRTAIEFAVRRLKGAFGVVVTERCVPGDGTTAGWLTLERPDGLIRVSVPP MAV_2362|M.avium_104 HVDPFTREQTELLAGTVLGGPVDPWVVDELLQRSSGNPLLLRGFLTAG-- Mb0393|M.bovis_AF2122/97 --LVTLTGAGGVGKTRLAAQLAAQIAGEF-GRAWFVDLAPITDPDLVPVT Rv0386|M.tuberculosis_H37Rv --LVTLTGAGGVGKTRLAAQLAAQIAGEF-GRAWFVDLAPITDPDLVPVT Mvan_5928|M.vanbaalenii_PYR-1 --LVTLTGAGGVGKTRLATQVAVAVVEGYPGGVWYVDLAPITDPALVAIT MMAR_2962|M.marinum_M --LVTLIGSGGVGKSRLAEQVVAQLAAQFVDGVRYVDLGSITDPAVAPIT MLBr_01753|M.leprae_Br4923 --LLTLVGPGGVGKTRLALQVVARVADEFSGELSYFDLAPDTDHDIFPIT MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 --LVTLTGVGGVGKTRLALEVATRVADEFPDGVWLFELAAVSDPAAVPDA MAB_3361|M.abscessus_ATCC_1997 --AGGFGWPDGGRLAGQIEQTFLRRVQQLPAHTQTLLLAAATDPLGDVTL TH_3225|M.thermoresistible__bu --AGGFVSPGAGSAPSRIEENYVHRIRALPAQTRRLLLIAAAEPIGDSAL Mflv_4504|M.gilvum_PYR-GCK MDAGRLHALISHRLGRTLTRPVVLRIAEMSGGNPFYALELAHTHVNSGDS MAV_2362|M.avium_104 ----RDTGALFRTAEGWQLRGPLRGDRELHDALEYRLQSLSSE------- Mb0393|M.bovis_AF2122/97 VAGALGLHDQPGRSTTDTVLRFLGGRPALVVLDNCEHLLDATAALVLALV Rv0386|M.tuberculosis_H37Rv VAGALGLHDQPGRSTTDTVLRFLGGRPALVVLDNCEHLLDATAALVLALV Mvan_5928|M.vanbaalenii_PYR-1 VARALGLPDQPGRSTVDTIVRFIADRRMLVVLDNCEHLLDACATLIDALL MMAR_2962|M.marinum_M MARALGLPNQPGRSAMDTLLHHLGDRQMLLLVDNCEHLLDASAPRLGAML MLBr_01753|M.leprae_Br4923 VL--------------DNLRRCIGDRRMLMVLDNCEYLLDVCANVMTTLL MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 VAAVLGITQQAGKTVTQSVATALERRVRLLVFDNCEHVRDAAADLIEAIL MAB_3361|M.abscessus_ATCC_1997 LAR---------------AAQQLGIPMHAIAPAEAADLVELSTRVRFRHP TH_3225|M.thermoresistible__bu FLR---------------AAALMGIAVDALAPAEAARVIQFGPRMRFFHP Mflv_4504|M.gilvum_PYR-GCK PP----------------AAEPPLPATLADVVRRRVGLLDDATRTLLLGV MAV_2362|M.avium_104 -------------------EREVVEILATAGLLNWDILRDICDAEAVAAL Mb0393|M.bovis_AF2122/97 KACRGVRLLATCREPLRVEGEVSYRVPSLSLSD----EAVEMFCYRAQRV Rv0386|M.tuberculosis_H37Rv KACRGVRLLATCREPLRVEGEVSYRVPSLSLSD----EAVEMFCYRAQRV Mvan_5928|M.vanbaalenii_PYR-1 GACPALAMLATSREPIAVAGEQTWRVPPLALDD----DAIELFTDRARRA MMAR_2962|M.marinum_M RDCPGLRLLVTSREPIKVAGEVTWRVPPLAVG-----DAIALFTDRARLA MLBr_01753|M.leprae_Br4923 GACPSLTILATSREPIGVAGEVIWRVSMLSPAD----EAVELFTERAALV MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 AGSTTVRILATSRERLEVPDEQLWSVPSLDVGGGVVSAAGTLFVERAQSV MAB_3361|M.abscessus_ATCC_1997 LVRSAVYISANPLERRRIHGVLAGATDPGADPD-----------RRAWHR TH_3225|M.thermoresistible__bu LMRSAAYRAADPRDRRAVHRALAEATDPGADPD-----------RRAWHA Mflv_4504|M.gilvum_PYR-GCK ACVADPTVELLARAHGASTDEITAGLERAEAAG--------IVVLEGNRV MAV_2362|M.avium_104 ERRGLIRLVTDGSHAVAQLTHPMLGEAATRHAG----------------- Mb0393|M.bovis_AF2122/97 RPDFRLTDDNSAAVT-EICKRLDGLPLAIELAAARLRSMTLDEIIDGLRD Rv0386|M.tuberculosis_H37Rv RPDFRLTDDNSAAVT-EICKRLDGLPLAIELAAARLRSMTLDEIIDGLRD Mvan_5928|M.vanbaalenii_PYR-1 RPDFIISADDAAAVS-EICHRLDGMPLAIELAAARVRALSLTEIVDGLHD MMAR_2962|M.marinum_M QPDFALTDDNAGTVS-QICRRLDTQPLGIELAAARVRTLSLAEISAGLDD MLBr_01753|M.leprae_Br4923 QPGFSVTDGNRQIVT-EICQRLDGMPLAIELAAARIRTLSLTEIADGLDD MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 APGFAPTDAQDAAAIGEICRRLDGIPLAIELAASRMASMTPIEVRDRLDH MAB_3361|M.abscessus_ATCC_1997 AHAAAGTDEAIAWELEQSAGRAQAKGGVLAAAAFLQRATELTADPA---- TH_3225|M.thermoresistible__bu ANGVTGTDDAVAAELEKSAARAQQRGGIAATATFLERAVVLTADPG---- Mflv_4504|M.gilvum_PYR-GCK RFTHPLLAGGVYTDAGPTARRAMHRAIASVESHPELRARHLALAASSGDD MAV_2362|M.avium_104 -MVRTRQLNGKLARALQKHERTGSRHLRLPHLQSRIRLAEFMLHSDMEPD Mb0393|M.bovis_AF2122/97 RFALLTGGARTAAHRQQTLWASVDWSYTLLTEPERTLFRRLAVFVGCFFV Rv0386|M.tuberculosis_H37Rv RFALLTGGARTAAHRQQTLWASVDWSYTLLTEPERTLFRRLAVFVGCFFV Mvan_5928|M.vanbaalenii_PYR-1 RFRLLTGGSRTAVRRQQTLRASVDWSHGLLTDPERVLFRRLAVFAGGFDL MMAR_2962|M.marinum_M KIRLLTGGARTAVPRQQTLRASLEWSHGLLTDTERVLFRRLGVFVGGFDL MLBr_01753|M.leprae_Br4923 RFRLLTGGARTAVRRQQTLRASMDWSYALLTESERALFRRLSAISGTFDL MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 RFRLLVG-SRRGLGRHQTLRHAVAWSYDHLSDAEKVLLERCSVFAGGFDL MAB_3361|M.abscessus_ATCC_1997 ----ARGRRALAAAQSKYDAAAFDAARELLGVADMTPLDPLARARATRLR TH_3225|M.thermoresistible__bu ----LRGRRALAAAQAKRDAADSAAAHDLLAIAERAPLSALEWARAVHLR Mflv_4504|M.gilvum_PYR-GCK EIFAALDQAADSARARGAPAAAAELMDLALGLGAHDPMRRLKAAENHFLA MAV_2362|M.avium_104 LDVITEAARDALAMSNVQLGEELARFALDRGGGLPAALVLAEAVSWQGRG Mb0393|M.bovis_AF2122/97 DDAQAVACSGDVQR-YQVLDEITLLVDKSLVMADDNSGRTCYRLCETMRH Rv0386|M.tuberculosis_H37Rv DDAQAVACSGDVQR-YQVLDEITLLVDKSLVMADDNSGRTCYRLCETMRH Mvan_5928|M.vanbaalenii_PYR-1 DGAQAITVDGEVHR-YEVVDLLTLLVDKSLLIAENTAGRTRYRLLETVRQ MMAR_2962|M.marinum_M QAAQAVAAFGDVHP-RDVLGDLSQLVDKSLVVADSSNGRTRYRRFEGVGQ MLBr_01753|M.leprae_Br4923 KVAYAVGHDDLEEP-DQVFDRLTMLIDKSLVIVEGRQGGSRYRLLETVRQ MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 QSACAVAGSADTHDDYEVLDLLDALVGKSLLIVDRLSGRSRFSMLETIRE MAB_3361|M.abscessus_ATCC_1997 AKIAFAESRVGAFGSVTVSEAAIGLVEAARCLENLDDNLARETYLDAVGA TH_3225|M.thermoresistible__bu AQLEFARSRAGDAGGPPVGQTAAALLTAAQLLQDVDAPAARESYLEAFAA Mflv_4504|M.gilvum_PYR-GCK GDTAKAAAALGEVG---SIEPPILRAMATSLLATVRMYDNEHRQAVDLLR MAV_2362|M.avium_104 EEAGFVLAHAEPDGDDDWLIARWGCLRAANLFWGCGDAEAARREADTVKK Mb0393|M.bovis_AF2122/97 YALEKLSEAGEVDAVFARHRDYYTALAARVDNPGPS-DYSHCLDQAETEI Rv0386|M.tuberculosis_H37Rv YALEKLSEAGEVDAVFARHRDYYTALAARVDNPGPS-DYSHCLDQAETEI Mvan_5928|M.vanbaalenii_PYR-1 YAQEKLGESGEADTLRARHRDHYTARAAELDAPSVA-GHERRLNQTDIEM MMAR_2962|M.marinum_M LALEKLREAGEADIARARHCDHYTAVVAPLDLPARA-DYDFLLARVEGEL MLBr_01753|M.leprae_Br4923 YAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDI-DHEQLVEQVETEL MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 FAEEQLVTRGQALAARTAHARHFAQRLPDVAAVWDSPRQPEAYTWLTAEL MAB_3361|M.abscessus_ATCC_1997 AMYGGRLCPRGGAVEVAEPARLAPAGAQP-----------------ARPS TH_3225|M.thermoresistible__bu LMYAGRLAPSGALLEAADAVQAAFARAPEG----------------SRAV Mflv_4504|M.gilvum_PYR-GCK SALDDAADNVPVQVQVLLRLSFALNSIGELDDARRY-----ARDAVKLAE MAV_2362|M.avium_104 RVSSEAG--LHLIDALELSMAFFRGDVETTTELGPG----------LCES Mb0393|M.bovis_AF2122/97 DNLRAAFVWNRENSDTEGALALASSLLRVWMTRG-RIQEGRAWFDSILAD Rv0386|M.tuberculosis_H37Rv DNLRAAFVWNRENSDTEGALALASSLLRVWMTRG-RIQEGRAWFDSILAD Mvan_5928|M.vanbaalenii_PYR-1 DNLRAAFAWSRENANTDHSLLLASSLHPLWRARG-RLQEGQAWFDAALTD MMAR_2962|M.marinum_M ENLRAASAWLLESSDGESALMLASRLQPLWLVRG-RISEGRSWFDAALAG MLBr_01753|M.leprae_Br4923 DNLRSAFAWSRETGDIAGALQLASSLQPIWFGRG-HMYEGLAWFDSIFEH MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 ANLRLAFRWTADNNDLDDAASIATWVGFLGFLVN-RFEP-LTWVEEAIER MAB_3361|M.abscessus_ATCC_1997 DLLLDGLARRITHGAAASAQTLGEALTLIRCEAD-RPANTS-WMEQAFPI TH_3225|M.thermoresistible__bu DAFCQGMTQRIVGGISAAAAPLRVALTAMCELARSRPAEVVHWLVPAFPV Mflv_4504|M.gilvum_PYR-GCK ELGFPGATSAALAWAVHVDFQCGRGLDETALARAMKLYDSTFDVPIIFRA MAV_2362|M.avium_104 DAVPMATTWAAVPTCAALAATGRYSEVGRIADIGVRAAMSCGMGLHRFNI Mb0393|M.bovis_AF2122/97 ENARHLEVAAAVRARALADKALLDIFVDAAAG-----MEQAQQALVIARE Rv0386|M.tuberculosis_H37Rv ENARHLEVAAAVRARALADKALLDIFVDAAAG-----MEQAQQALVIARE Mvan_5928|M.vanbaalenii_PYR-1 YEARPGEADPAVYARALADRAFMDGHVGITDR-----LDQAQKALAMARD MMAR_2962|M.marinum_M --ASVLEVSPTVRARALADAAVLTMFVDVATS-----LESAAAALAIARE MLBr_01753|M.leprae_Br4923 KNIEHLVAPKEVLARAVANKVMLHAILASSPPDGSDLVTQAQQALTMARE MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 AVDHPKLAFLHVLASQCYTTGRVQEAIR---------------------- MAB_3361|M.abscessus_ATCC_1997 ALESATHEVWDDDMWHHLA------------------------------- TH_3225|M.thermoresistible__bu LQESAGHELWDENLVDALS------------------------------- Mflv_4504|M.gilvum_PYR-GCK PFVHALAMSWTGRLEQAHQ------------------------------- MAV_2362|M.avium_104 GISEIIAATDAGDDRAAER------------------------------- Mb0393|M.bovis_AF2122/97 VDEPALLSRALTACGLIAVAVARADAAASYFAEAIDLARAVDDRWRLAQI Rv0386|M.tuberculosis_H37Rv VDEPALLSRALTACGLIAVAVARADAAASYFAEAIDLARAVDDRWRLAQI Mvan_5928|M.vanbaalenii_PYR-1 IDDPALLVRALTACG--GLAAYNADVARPLLAEAVDLARSMGDKWMLAET MMAR_2962|M.marinum_M LDDPASLVRALTACGLTASFSHHTEAVGQYFAEAASLAEELDDQWGLSQI MLBr_01753|M.leprae_Br4923 IGDSAVLARALTACG--FSSGYDTEVARPYFAEAVELARTQGDKWTLSQI MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 ------------------------------YADEAARLLATDRYEVPFGI MAB_3361|M.abscessus_ATCC_1997 -------------------------------TRAVHIAREVGALSLLPAA TH_3225|M.thermoresistible__bu -------------------------------EAVVRQARDAGALAGLPQA Mflv_4504|M.gilvum_PYR-GCK -----------------------------ELTAVRGVCLERGAESDMMAI MAV_2362|M.avium_104 -------------------------------IYKRYAAMAEGLPGAEAMV Mb0393|M.bovis_AF2122/97 LTFQAVDAVVAG-DPVAARPAAQEARELAAAIGDHSNALWCRWCLGYAQL Rv0386|M.tuberculosis_H37Rv LTFQAVDAVVAG-DPVAARPAAQEARELAAAIGDHSNALWCRWCLGYAQL Mvan_5928|M.vanbaalenii_PYR-1 LAWQAYAALMGGGDPVAARTAGEEARELADEMGDGFVSRICGWLLGIAHH MMAR_2962|M.marinum_M LSWQSNAAVVAG-DAIAARRIGTEGRDLADAIGDRFNSWLCRLSLGYAQL MLBr_01753|M.leprae_Br4923 RLWGVVGFCVSG-DPVALRAAAEAADDLAQEIGDRFVSLQCRLLLSIAQL MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 EGWPSGACTSSG-------------------------------------- MAB_3361|M.abscessus_ATCC_1997 LIYRAGMHVHAG-------------------------------------- TH_3225|M.thermoresistible__bu LVYRAGVHLLFG-------------------------------------- Mflv_4504|M.gilvum_PYR-GCK AGFLAINHLWRG-------------------------------------- MAV_2362|M.avium_104 DAMLGVVRLARG-------------------------------------- Mb0393|M.bovis_AF2122/97 MRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAFALAYQGELSAARA Rv0386|M.tuberculosis_H37Rv MRGELAAAAAQFGEVVDEAEASQEVLHKANSLQGLAFALAYQGELSAARA Mvan_5928|M.vanbaalenii_PYR-1 FQGDLDAALALADGVVSESDVAHDTLNGCCGELVLAHSLAQRGDTDAARA MMAR_2962|M.marinum_M WQGDLTGATTQFGALSEAENLASLSSK------GLGDALAYRGDVDAART MLBr_01753|M.leprae_Br4923 WQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQTRALVHR-DVSAALV MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 -------------------------------------------HPEQSVE MAB_3361|M.abscessus_ATCC_1997 ----------------------------------------ELDAAAELVQ TH_3225|M.thermoresistible__bu ----------------------------------------EFGLADTLLT Mflv_4504|M.gilvum_PYR-GCK -------------------------------------QITDAEAEAAEAV MAV_2362|M.avium_104 -------------------------------------------------E Mb0393|M.bovis_AF2122/97 AADAAL-EAAELGEYFAGMGYSALTTAALAAGDVQTAQHASEAAWRNLSL Rv0386|M.tuberculosis_H37Rv AADAAL-EAAELGEYFAGMGYSALTTAALAAGDVQTAQHASEAAWRNLSL Mvan_5928|M.vanbaalenii_PYR-1 AAQVSLNVAVEVSPVHAGLAHAALAVANLAAGDVTAAEAASDSATRSFGP MMAR_2962|M.marinum_M AAEAALERAAESSEYTLGLGYSTVALAALAGGDVETARNASDLAWHKLSV MLBr_01753|M.leprae_Br4923 TAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAVEASEACRPHLGA MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 LCRTQLALGHDTHTLTLGCLVLALTIKGQCDEAEQLADALIESAEATRNP MAB_3361|M.abscessus_ATCC_1997 EADAISAATGH-APIRYHSLILAAWRGSEPTAIRLIDEAMRDGAARGEGR TH_3225|M.thermoresistible__bu EAESITAATDHRGPVRYHRLIIAAWRGDAVEAARLIEAAAADGEARGEGR Mflv_4504|M.gilvum_PYR-GCK ERAEQLGGDDVLIIPMTVRGAIAAYAGRVDDARADARWVLAAVRNRKASH MAV_2362|M.avium_104 FPAACAAFTRSISLFAKGFPSPWLVVVGAFQAQAEGARGDSTAAAAALWR Mb0393|M.bovis_AF2122/97 ALPLSAAVQRAFNAQAALAGGDLSAARR----WCDDAVQSMTGHHLAMAL Rv0386|M.tuberculosis_H37Rv ALPLSAAVQRAFNAQAALAGGDLSAARR----WCDDAVQSMTGHHLAMAL Mvan_5928|M.vanbaalenii_PYR-1 SE-VAGIQDPNVAAQIACTRGDLDTARS----LVDGAVSITRGVHRASAL MMAR_2962|M.marinum_M QP-YAAMFWHSFRAEIALACGNVAGAKR----CADEAVSVTTGWHRALAL MLBr_01753|M.leprae_Br4923 DHGLVAIH-LELMAAVALARGDVIVARR----LADNSVSATTGWHQMAAL MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 AALCYALLAYGFTFRDTNPASALAAMRR----GLRIAQDTGNRNSETHLA MAB_3361|M.abscessus_ATCC_1997 LLGAMGYAAGVLNNSLGRYELAFMAARR----ACEHEDLGLYSWCLIELI TH_3225|M.thermoresistible__bu LMGLTGYAAALLYNGIGRYREALAAART----TCEYEDLGFYSWCLHELV Mflv_4504|M.gilvum_PYR-GCK IADWPGMTLCFLEESLGNHREALAALDDSFIAAGPPTTELMYAWHLPDAI MAV_2362|M.avium_104 ADRAYGPHAAVFLPELELARAWERAAAG------DTQAATTHATQAAEIA Mb0393|M.bovis_AF2122/97 ATRARIAVAEGKREEAERDAHKALACAAESGAHLDLPDVLECLAGL---- Rv0386|M.tuberculosis_H37Rv ATRARIAVAEGKREEAERDAHKALACAAESGAHLDLPDVLECLAGL---- Mvan_5928|M.vanbaalenii_PYR-1 TTRARIAIAQGDPEQAERNAHDALSLAAGVGARLEVPDTLECLARV---- MMAR_2962|M.marinum_M TTRARVAMAEGEPEQAERAAYEALTCAADVGARTCLPDILECLGAL---- MLBr_01753|M.leprae_Br4923 TTRARIAMAQGEPELARADIHAALACGADIQASLGISDSMELLAEL---- MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 AVLCRVEAKYGDPLSALDHFTLAIHNHHEAGNTTLISTPLAVLAAF---- MAB_3361|M.abscessus_ATCC_1997 EAAVRCGEHDTAVKAFGQLEERALAAQSDWSQGMVARSRALITVGH---- TH_3225|M.thermoresistible__bu EAAARVGETDTAHRALGDIEERAGASGTPWGLGALAGARALLADGD---- Mflv_4504|M.gilvum_PYR-GCK EAMVGVGRLDDAEILTAALERNGVEHDRRWMRAVGARCRAMLLAAHGDVA MAV_2362|M.avium_104 RAAGMHAAEMRTRHAAVRFGDRSQTARLERLARILDTPLAEAAADH---- Mb0393|M.bovis_AF2122/97 ASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYVQSVTALRDAMGEK Rv0386|M.tuberculosis_H37Rv ASDAGTHHAAARLFGAAEAIRQQIGSVRFAIYRSDYVQSVTALRDAMGEK Mvan_5928|M.vanbaalenii_PYR-1 VGDGGSHHEAARLCGAAEAIRGRTGAVRFRIYDADHETTVTTLRDALGDK MMAR_2962|M.marinum_M AADQGRDREAARVYGAAEGIRQRIGAMRFKIYDAGYQKSVAALHATMSTD MLBr_01753|M.leprae_Br4923 ISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLRGAMGCK MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 FDRLGRYEAAATIAGFAFHPITEASFP-------ELRTTISHLRDALGDH MAB_3361|M.abscessus_ATCC_1997 DAEPHYREAIQRLTNTRISAHLARAHLIYGEWLRRCNRRSDARTELTAAH TH_3225|M.thermoresistible__bu EADRLFREALDHLSRSRVVVHRARVHLTYGEWLRREHRRGEARRELNEAH Mflv_4504|M.gilvum_PYR-GCK AAEQMAHRAISEHDHLPMPFERARTRLLLGQLQRRLRQKATAAKNLTDAL MAV_2362|M.avium_104 --ARGLTQRDGDLLDAAAQQFADLGALACAADAAAQAAGEHARRGDRGKK Mb0393|M.bovis_AF2122/97 DFAAAWAEGAALSIKETIAYAQRGHSWRKRPATGWESLTPTEIDVVRLVG Rv0386|M.tuberculosis_H37Rv DFDAAWAEGAALSIKETIAYAQRGHSWRKRPATGWESLTPTEIDVVRLVG Mvan_5928|M.vanbaalenii_PYR-1 AFEAAWTEGSATSITEAIAYAQRGRGERKRPSSGWASLTPTELDVVGLVS MMAR_2962|M.marinum_M EFDTAWAHGAAFSAEEAIDYLQHRRGERKRATSGWAALTRAELNVVRLVG MLBr_01753|M.leprae_Br4923 DFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNVIRLVS MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 AYESFSQSGAAMTTAAMATYAYHQIDHARTEFQAR--------------- MAB_3361|M.abscessus_ATCC_1997 GSFVNMG-TAAFAERAERELRATGAKVRKRSASSEKALTAQEAQIARMAG TH_3225|M.thermoresistible__bu GMFTRMG-AQGFAERSRRELIAVGEKVRRQPLTSGDELTAQEAQIAGLAA Mflv_4504|M.gilvum_PYR-GCK HTFEQLG--------TPLWAQRARSELARAVVAPAEGLTPSEQKVAEMAA MAV_2362|M.avium_104 --FESSAWAHALASRYELHTPAVEAAARPLPFSGR------ERQIVNLVA Mb0393|M.bovis_AF2122/97 EGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT---- Rv0386|M.tuberculosis_H37Rv EGLANKDIATRLFVSPRTVQTHLTHVYTKLGFTSRLQLAQAAARRT---- Mvan_5928|M.vanbaalenii_PYR-1 EGLSNKDIAARLFVSPRTVQTHLTHVYTKLCLASRVQLAQEAARHT---- MMAR_2962|M.marinum_M QGLSNKDIAQRLFLSPRTVQTHLTHVYTKLGFNSRVQLAQQAAQHS---- MLBr_01753|M.leprae_Br4923 EGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN---- MSMEG_0545|M.smegmatis_MC2_155 -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 -------------------------------------------------- MAB_3361|M.abscessus_ATCC_1997 QGLTNQEIAAQLFISSHTVEWHLRKVFAKRGITSRRQLRSGR-------- TH_3225|M.thermoresistible__bu DGLTNQEIGAQLFLSVHTVEWHLRKVFVKLGITSRRQLRAAPRVTATW-- Mflv_4504|M.gilvum_PYR-GCK AGATNKDIAAAMFISSKTVEHNLTRIYRKLGISSRAELGRRMDQPGL--- MAV_2362|M.avium_104 AGLSNREIADRLVISVRTVEGHLYRLFTKLGINSREQLTLLVAREPRGRR Mb0393|M.bovis_AF2122/97 --------------------- Rv0386|M.tuberculosis_H37Rv --------------------- Mvan_5928|M.vanbaalenii_PYR-1 --------------------- MMAR_2962|M.marinum_M --------------------- MLBr_01753|M.leprae_Br4923 --------------------- MSMEG_0545|M.smegmatis_MC2_155 --------------------- MUL_2743|M.ulcerans_Agy99 --------------------- MAB_3361|M.abscessus_ATCC_1997 --------------------- TH_3225|M.thermoresistible__bu --------------------- Mflv_4504|M.gilvum_PYR-GCK --------------------- MAV_2362|M.avium_104 ELLGHSNPSLGDQDDVHPHAG