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M. marinum M MMAR_3522 (-)

annotation: LuxR family transcriptional regulator
coordinates: 4329202 - 4331913
length: 903

MFEVEPPSVWHSALVAADLGGPPSGIVTFLFTDVEGSTRRWESDPDRMRAALAAHDAVLKRTIQTHRGWL
FKHTGDGVCAAFASPRSAVDAAVDAQRALELPVRMGLATGEAEPHDADYFGAVLNRAARVMATGHGGQIL
LTDSTANLISGVDLLDLGSRRLRDLPAPVRVFQVRAPGLRTDFPALRAPDTSPGNLRPALTSFVARAAEI
GQVQTALQVHRLVTLTGVGGVGKTRLALEVATRVADEFPDGVWLFELAAVSDPAAVPDAVAAVLGITQQA
GKSVTQSVATALEGRVRLSVFDNCEHVRDAAADLIEAILAGSTTVRILATSRERLEVPDEQLWSVPSLDV
GGGVVSAAGTLFVERAQSVAPGFAPTDAQDAAAIAEICRRLDGIPLAIELAASRMASMTPIEVRDRLDHR
FRLLVGSRRGLGRHQTLRHAVAWSYDHLSDAEKVLLERCSVFAGGFDLQSACAVAGSADTHDDYEVLDLL
DALVGKSLLIVDRLSGRSRFSMLETIREFAEEQLVTRGQALAARTAHARHFAQRLPDVAAVWDSPRQPEA
YTWLTAELANLRLAFRWTADNNDLDDAASIATWVGFLGFFVNRFEPLTWVEEAIERAVDHPKLAFLHVLA
SQCYMTGRVQEAIRYADEAARLLATDRYEVPFGIEGWPSGAYTSSGHPEQSVELCRTQLALGRDTHTLTL
GCLVLALTIKGQCNEAEQLADALIESAEATRNPAALCYALLAYGFTFRDTNPASALAAMRRGLRIAQDTG
NRNSETHLAAVLCRVEAKYGDPLSALDYFTLAIHNHHEAGNTTLISTPLAVLAAFFDRLGRYEAAATIAG
FAFHPITEASFPELRTTISHLRDALGDHAYESFSQSGAAMTTAAMATYAYHQIDHARTELQAR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_3522--100% (903)LuxR family transcriptional regulator
M. marinum MMMAR_0123-e-11936.30% (843) LuxR family transcriptional regulator
M. marinum MMMAR_2962-2e-9237.60% (609) transcriptional regulatory protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2515c-1e-11041.98% (617) LuxR family transcriptional regulator
M. gilvum PYR-GCKMflv_2091-5e-1534.46% (148) putative adenylate/guanylate cyclase
M. tuberculosis H37RvRv2488c-1e-11041.98% (617) LuxR family transcriptional regulator
M. leprae Br4923MLBr_01753-6e-8535.14% (700) putative transcriptional regulator
M. abscessus ATCC 19977MAB_4771-1e-1135.71% (126) putative adenylate cyclase
M. avium 104MAV_1250-8e-1533.33% (168) adenylate and guanylate cyclase catalytic domain-containing
M. smegmatis MC2 155MSMEG_5018-1e-1231.29% (163) adenylate and guanylate cyclase catalytic domain-containing
M. thermoresistible (build 8)TH_1244-4e-1632.54% (169) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_2743-0.098.52% (877) LuxR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_5928-1e-11841.07% (655) regulatory protein, LuxR

CLUSTAL 2.0.9 multiple sequence alignment


MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               ------------------------------MFEVEPPSVWHSALVAADLG
MUL_2743|M.ulcerans_Agy99           --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
Rv2488c|M.tuberculosis_H37Rv        MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
Mvan_5928|M.vanbaalenii_PYR-1       -----------------------------------------------MSE
MLBr_01753|M.leprae_Br4923          ----------------MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTD
MAB_4771|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_5018|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               GPPSGIVTFLFTDVEGSTRRWESDPDRMRAALAAHDAVLKRTIQTHRGWL
MUL_2743|M.ulcerans_Agy99           ------MTFLFTDVEGSTRLWESDPDRMRAALAAHDAVLTRTIQTHRGWL
Mb2515c|M.bovis_AF2122/97           LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRGVC
Rv2488c|M.tuberculosis_H37Rv        LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRGVC
Mvan_5928|M.vanbaalenii_PYR-1       LVPTGTVTLLLADVQGSTQLWETQPETMTAAVAQLDRTLTDLVSDHDGVR
MLBr_01753|M.leprae_Br4923          LHRGCTVTLFLGDVEGLAELSETQPDEAADAIARLDCVVSEAVAAHGGVQ
MAB_4771|M.abscessus_ATCC_1997      ------------------------------------------MPESDELN
MSMEG_5018|M.smegmatis_MC2_155      ----MVSQQVQPDIQPLLEGLDGAARSQREELINWLLSRGISVDQIGQAI
                                                                                      

MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      -----------------------------VAARPLPLAVAAAPGSPIPR-
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               FKHTGDG--VCAAFASPRSAVDAAVDAQRALELPVR--MGLATGEAEPH-
MUL_2743|M.ulcerans_Agy99           FKHTGDG--VCAAFASPRSAVDAAVDAQRALELPVR--MGLATGEAEPH-
Mb2515c|M.bovis_AF2122/97           PVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSP-
Rv2488c|M.tuberculosis_H37Rv        PVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSP-
Mvan_5928|M.vanbaalenii_PYR-1       PVEQGEGDSFVVAFTRASDAVACALALQRAPLAPIRLRIGVHTGEVRLR-
MLBr_01753|M.leprae_Br4923          QVVQGVRGNFLATFARASDATACALDLQLAPIVPVRFRIALHTGEVQISN
MAB_4771|M.abscessus_ATCC_1997      AVVDAAVEQVLLGGPRRYTRSQVSQLSGVPVERARTLWVALGFAAADSD-
MSMEG_5018|M.smegmatis_MC2_155      TPMLLASRRVAGDDGTYVSAREISEQTGLDLDLLQRLQRAMGLPAVEDP-
                                                                                      

MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               -DADYFGAVLNRAARVMATGHGGQILLTDSTANLISGVD-----LLDLGS
MUL_2743|M.ulcerans_Agy99           -DADYFGAVLNRAARVMATGHGGQILLTDSTANLISGVD-----LLDLGS
Mb2515c|M.bovis_AF2122/97           DEGNCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGT
Rv2488c|M.tuberculosis_H37Rv        DEGNCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGT
Mvan_5928|M.vanbaalenii_PYR-1       DEGNYVGPTINRTARLRELAHGGQTVLSGTTSDLVADLLPDGGWLSDLGT
MLBr_01753|M.leprae_Br4923          DDVNNVVFMMVQAAGLLDLACGGQTVLSSITGDLVVDGLPADTWLVDLGS
MAB_4771|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_5018|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAV_1250|M.avium_104                ----------MG-----DVLHVTVYILAGLAAVEAGALAVLWRRLVRSRA
TH_1244|M.thermoresistible__bu      ---------RVGQDGAVTQIAIVVVALAGLALAEAVALAVLWGRLRRERR
Mflv_2091|M.gilvum_PYR-GCK          -------------------MLILVCVLAVLAAGLGIALAVQTRRLTSARQ
MMAR_3522|M.marinum_M               RRLRDLPAPVRVFQVRAPGLRTDFPALRAPDTSPGN-LRPALTSFVARAA
MUL_2743|M.ulcerans_Agy99           RRLRDLPAPVRVFQVRAPGLRTDFPALRAPDTSPGN-LRPALTSFVARAA
Mb2515c|M.bovis_AF2122/97           YRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVD
Rv2488c|M.tuberculosis_H37Rv        YRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVD
Mvan_5928|M.vanbaalenii_PYR-1       HRLRDLPRPERVVQLCHADLSNEFPPLRAREEIGVQRLPAQLTSFVGRVD
MLBr_01753|M.leprae_Br4923          HLLRDLARPVRVMQLCHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAA
MAB_4771|M.abscessus_ATCC_1997      --------DEVAFTDADVSAIRTFAALGSATAANQQSQIAAARTLGQAMA
MSMEG_5018|M.smegmatis_MC2_155      ---------DAAVLLRADAEAVTFSQQFIDLGIDADQVVLITRVLAEGLS
                                                           .                    :     

MAV_1250|M.avium_104                ELDELRQRTDARNWLLAGGREAVKTVWNTANLVRKEGFG--AAVRSSIEE
TH_1244|M.thermoresistible__bu      AADELRRRLDTRTTLMAGGREAVRTVWQTANILRTDGLG--AAARSSIED
Mflv_2091|M.gilvum_PYR-GCK          EAEELRHRLDTRQLLVSGGTKAVKTVWQTANILRKDGFG--AAVRSSIEE
MMAR_3522|M.marinum_M               EIGQVQTALQVHRLVTLTGVGGVGKTRLALEVATRVADE--FPDGVWLFE
MUL_2743|M.ulcerans_Agy99           EIGQVQTALQVHRLVTLTGVGGVGKTRLALEVATRVADE--FPDGVWLFE
Mb2515c|M.bovis_AF2122/97           EVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADG--YPDGVWYVN
Rv2488c|M.tuberculosis_H37Rv        EVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADG--YPDGVWYVN
Mvan_5928|M.vanbaalenii_PYR-1       DMAQVRGLMDANRLVTLTGAGGVGKTRLATQVAVAVVEG--YPGGVWYVD
MLBr_01753|M.leprae_Br4923          QIKELQELLTEKRLLTLVGPGGVGKTRLALQVVARVADE--FSGELSYFD
MAB_4771|M.abscessus_ATCC_1997      RLAEWQADLLTREVGGRLAAEGDDASAESSANAATQTIA--TLTALQNYA
MSMEG_5018|M.smegmatis_MC2_155      RAAEVMRAAALAAVLEPGASELETAKAAEGLVAEAAPLLGPMIQDMLFVQ
                                       :              .                               

MAV_1250|M.avium_104                LADWAEVERP--------------------DLARVTPDGRVVILFTDIEE
TH_1244|M.thermoresistible__bu      LADWAEVERP--------------------DLARLAANGKVVILFSDIEG
Mflv_2091|M.gilvum_PYR-GCK          LADWAEVERP--------------------DLARLSLNGRLTIMFSDIEE
MMAR_3522|M.marinum_M               LAAVSDPAAVPDAVAAVLGITQQAGKSVTQSVATALEGRVRLSVFDNCEH
MUL_2743|M.ulcerans_Agy99           LAAVSDPAAVPDAVAAVLGITQQAGKTVTQSVATALERRVRLLVFDNCEH
Mb2515c|M.bovis_AF2122/97           LAPITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEH
Rv2488c|M.tuberculosis_H37Rv        LAPITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEH
Mvan_5928|M.vanbaalenii_PYR-1       LAPITDPALVAITVARALGLPDQPGRSTVDTIVRFIADRRMLVVLDNCEH
MLBr_01753|M.leprae_Br4923          LAPDTDHDIFPITVL--------------DNLRRCIGDRRMLMVLDNCEY
MAB_4771|M.abscessus_ATCC_1997      WQRHLAAALHR-------------------ANETGSTTRQLLVGFADMVG
MSMEG_5018|M.smegmatis_MC2_155      LRHAMETEAVDASER--------------AEGVPLPGARLVTVAFADIVG
                                                                                : :   

MAV_1250|M.avium_104                S-----TALNERIGDRAWVKLISS--------------------------
TH_1244|M.thermoresistible__bu      S-----TALNNRIGDRAWVRLIDR--------------------------
Mflv_2091|M.gilvum_PYR-GCK          S-----TALNERIGDRAFVRLIGR--------------------------
MMAR_3522|M.marinum_M               VRDAAADLIEAILAGSTTVRILATSRERLEVPDEQLWSVPSLDVGGGVVS
MUL_2743|M.ulcerans_Agy99           VRDAAADLIEAILAGSTTVRILATSRERLEVPDEQLWSVPSLDVGGGVVS
Mb2515c|M.bovis_AF2122/97           LLDGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLGHG-----
Rv2488c|M.tuberculosis_H37Rv        LLDGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLGHG-----
Mvan_5928|M.vanbaalenii_PYR-1       LLDACATLIDALLGACPALAMLATSREPIAVAGEQTWRVPPLALDD----
MLBr_01753|M.leprae_Br4923          LLDVCANVMTTLLGACPSLTILATSREPIGVAGEVIWRVSMLSPAD----
MAB_4771|M.abscessus_ATCC_1997      Y-----TRLSRHLDPDELASLLET--------------------------
MSMEG_5018|M.smegmatis_MC2_155      F-----TRLGEVVPPEQLEQLANS--------------------------
                                            :   :       :                             

MAV_1250|M.avium_104                -----------------------HDKLVSDLVRRQSGH------------
TH_1244|M.thermoresistible__bu      -----------------------HSRLVRRFVKKHDGY------------
Mflv_2091|M.gilvum_PYR-GCK          -----------------------HDKSVRKFVDKHEGH------------
MMAR_3522|M.marinum_M               AAGTLFVERAQSVAPGFAPTDAQDAAAIAEICRRLDGIPLAIELAASRMA
MUL_2743|M.ulcerans_Agy99           AAGTLFVERAQSVAPGFAPTDAQDAAAIGEICRRLDGIPLAIELAASRMA
Mb2515c|M.bovis_AF2122/97           EAIELFTDRAREARPELEIT-ADNLALVTEICHRLDGIPLAIELAASRVR
Rv2488c|M.tuberculosis_H37Rv        EAIELFTDRAREARPELEIT-ADNLALVTEICHRLDGIPLAIELAASRVR
Mvan_5928|M.vanbaalenii_PYR-1       DAIELFTDRARRARPDFIIS-ADDAAAVSEICHRLDGMPLAIELAAARVR
MLBr_01753|M.leprae_Br4923          EAVELFTERAALVQPGFSVT-DGNRQIVTEICQRLDGMPLAIELAAARIR
MAB_4771|M.abscessus_ATCC_1997      -----------------------FETALTEAITTHGGW------------
MSMEG_5018|M.smegmatis_MC2_155      -----------------------LAEATRDVVRP----------------
                                                                                      

MAV_1250|M.avium_104                ------VVKSQGDGFMVAFARPEQAVRCGIELQRALRR------------
TH_1244|M.thermoresistible__bu      ------VIKSQGDGFMVAFARPEQAVRCSVELQRALR-------------
Mflv_2091|M.gilvum_PYR-GCK          ------VVKSQGDGFMVAFAKPEQAVRCGLDIQHSLA-------------
MMAR_3522|M.marinum_M               SMTPIEVRDRLDHRFRLLVG-SRRGLGRHQTLRHAVAWSYDHLSDAEKVL
MUL_2743|M.ulcerans_Agy99           SMTPIEVRDRLDHRFRLLVG-SRRGLGRHQTLRHAVAWSYDHLSDAEKVL
Mb2515c|M.bovis_AF2122/97           ALALTEIVDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVL
Rv2488c|M.tuberculosis_H37Rv        ALALTEIVDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVL
Mvan_5928|M.vanbaalenii_PYR-1       ALSLTEIVDGLHDRFRLLTGGSRTAVRRQQTLRASVDWSHGLLTDPERVL
MLBr_01753|M.leprae_Br4923          TLSLTEIADGLDDRFRLLTGGARTAVRRQQTLRASMDWSYALLTESERAL
MAB_4771|M.abscessus_ATCC_1997      ------VIKNVGDEVMFAAASAAAGARIAVAMNTAIT-------------
MSMEG_5018|M.smegmatis_MC2_155      ---PVRLIKTIGDAVMLVSPEPAALLDAVLNLVAATE-------------
                                          : .   . . .    .         :  :               

MAV_1250|M.avium_104                ---------------------NANRKRHEEIRVRIGIHMGRSVRRGDDLF
TH_1244|M.thermoresistible__bu      -------------------------KRPDRIRVRIGIHLGRSVRRGDDLF
Mflv_2091|M.gilvum_PYR-GCK          -------------------------RRPNDIRVRMGVHTGKSVLRGDDVF
MMAR_3522|M.marinum_M               LERCSVFAGGFDLQSACAVAGSADTHDDYEVLDLLDALVGKSLLIVDRLS
MUL_2743|M.ulcerans_Agy99           LERCSVFAGGFDLQSACAVAGSADTHDDYEVLDLLDALVGKSLLIVDRLS
Mb2515c|M.bovis_AF2122/97           FRRLAVFPSGFDLDGAQAAA-AGGDVQRYEVVDLLSLLADKSLVVTDDSD
Rv2488c|M.tuberculosis_H37Rv        FRRLAVFPSGFDLDGAQAAA-AGGDVQRYEVVDLLSLLADKSLVVTDDSD
Mvan_5928|M.vanbaalenii_PYR-1       FRRLAVFAGGFDLDGAQAIT-VDGEVHRYEVVDLLTLLVDKSLLIAENTA
MLBr_01753|M.leprae_Br4923          FRRLSAISGTFDLKVAYAVG-HDDLEEPDQVFDRLTMLIDKSLVIVEGRQ
MAB_4771|M.abscessus_ATCC_1997      ---------------------EAAQTIPDMPQIRVGLAYGQVLSRFGDLY
MSMEG_5018|M.smegmatis_MC2_155      -------------------------ADPEFPGLRVGLATGMAVSRAGDWF
                                                                      :    .  :       

MAV_1250|M.avium_104                GRNVAMAARVAAQAAGGEILVSQPVRDALSRS--------DGIRFD----
TH_1244|M.thermoresistible__bu      GRNVALAARVAGAAEGGEVLVSQAVRDALNSAGDAGSDEVAGFDVD----
Mflv_2091|M.gilvum_PYR-GCK          GRNVAMAARVAAAADGGEILVSSAVHRALADC--------EDLAFD----
MMAR_3522|M.marinum_M               GRSRFSMLETIREFAEEQLVTRGQALAARTAHARHFAQRLPDVAAVWDSP
MUL_2743|M.ulcerans_Agy99           GRSRFSMLETIREFAEEQLVTRGQALAARTAHARHFAQRLPDVAAVWDSP
Mb2515c|M.bovis_AF2122/97           GRTRYRLLETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAG
Rv2488c|M.tuberculosis_H37Rv        GRTRYRLLETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAG
Mvan_5928|M.vanbaalenii_PYR-1       GRTRYRLLETVRQYAQEKLGESGEADTLRARHRDHYTARAAELDAPSVAG
MLBr_01753|M.leprae_Br4923          GGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDID
MAB_4771|M.abscessus_ATCC_1997      GTVVNIAARLTGVARPGTILLDDGAAAALGDD--------GEFSLR----
MSMEG_5018|M.smegmatis_MC2_155      GSPVNLASRVTGVARPGTVLVAESTRQAIAAAD-------DRFRWS----
                                    *       .         :     .                 .       

MAV_1250|M.avium_104                ------DGREVELKGFSGTYRLFAVLAS----PDPG--------------
TH_1244|M.thermoresistible__bu      ------DGREVSLKGFPGRHRLFAVRGQAGFRPRPRPE------------
Mflv_2091|M.gilvum_PYR-GCK          ------EQRDVELKGFSGSHTLYPVRSA----SASR--------------
MMAR_3522|M.marinum_M               RQPEAYTWLTAELANLRLAFRWTADNNDLDDAASIATWVGFLGFFVNRFE
MUL_2743|M.ulcerans_Agy99           RQPEAYTWLTAELANLRLAFRWTADNNDLDDAASIATWVGFLGFLVNRFE
Mb2515c|M.bovis_AF2122/97           -HERRLNQAELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQ
Rv2488c|M.tuberculosis_H37Rv        -HERRLNQAELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQ
Mvan_5928|M.vanbaalenii_PYR-1       -HERRLNQTDIEMDNLRAAFAWSRENANTDHSLLLASSLHPLWRARGRLQ
MLBr_01753|M.leprae_Br4923          -HEQLVEQVETELDNLRSAFAWSRETGDIAGALQLASSLQPIWFGRGHMY
MAB_4771|M.abscessus_ATCC_1997      ------HLRGVRVKGFSRLGSHVLRARKR---------------------
MSMEG_5018|M.smegmatis_MC2_155      ------FAGARRLKGIKGDVKMFRARMRDQ--------------------
                                                : .:                                  

MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               P-LTWVEEAIERAVDHPKLAFLHVLASQCYMTGRVQEAIR----------
MUL_2743|M.ulcerans_Agy99           P-LTWVEEAIERAVDHPKLAFLHVLASQCYTTGRVQEAIR----------
Mb2515c|M.bovis_AF2122/97           EGLAWFAAALADHDAHPAGADPGLYARALADRALIDAVAG-----ITDRL
Rv2488c|M.tuberculosis_H37Rv        EGLAWFAAALADHDAHPAGADPGLYARALADRALIDAVAG-----ITDRL
Mvan_5928|M.vanbaalenii_PYR-1       EGQAWFDAALTDYEARPGEADPAVYARALADRAFMDGHVG-----ITDRL
MLBr_01753|M.leprae_Br4923          EGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVMLHAILASSPPDGSDLV
MAB_4771|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_5018|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               -------------------------------YADEAARLLATDRYEVP--
MUL_2743|M.ulcerans_Agy99           -------------------------------YADEAARLLATDRYEVP--
Mb2515c|M.bovis_AF2122/97           DDAQKALAIARDIEDPALLARALTACGGVAAYNADLARPWLAEAVGLARA
Rv2488c|M.tuberculosis_H37Rv        DDAQKALAIARDIEDPALLARALTACGGVAAYNADLARPWLAEAVGLARA
Mvan_5928|M.vanbaalenii_PYR-1       DQAQKALAMARDIDDPALLVRALTACGGLAAYNADVARPLLAEAVDLARS
MLBr_01753|M.leprae_Br4923          TQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVARPYFAEAVELART
MAB_4771|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_5018|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               ------------------FGIEGWPSGAYTS-------------------
MUL_2743|M.ulcerans_Agy99           ------------------FGIEGWPSGACTS-------------------
Mb2515c|M.bovis_AF2122/97           VGDKWRLAEVLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRS
Rv2488c|M.tuberculosis_H37Rv        VGDKWRLAEVLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRS
Mvan_5928|M.vanbaalenii_PYR-1       MGDKWMLAETLAWQAYAALMGGGDPVAARTAGEEARELADEMGDGFVSRI
MLBr_01753|M.leprae_Br4923          QGDKWTLSQIRLWG-VVGFCVSGDPVALRAAAEAADDLAQEIGDRFVSLQ
MAB_4771|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_5018|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               -----------SGHPEQSVELCR-----TQLALGRDTHTLTLGCLVLALT
MUL_2743|M.ulcerans_Agy99           -----------SGHPEQSVELCR-----TQLALGHDTHTLTLGCLVLALT
Mb2515c|M.bovis_AF2122/97           CRWALAAANLWQGNLEAAVGLSREVIGESDAAHDMVSSCAGQACLAHALA
Rv2488c|M.tuberculosis_H37Rv        CRWALAAANLWQGNLEAAVGLSREVIGESDAAHDMVSSCAGQACLAHALA
Mvan_5928|M.vanbaalenii_PYR-1       CGWLLGIAHHFQGDLDAALALADGVVSESDVAHDTLNGCCGELVLAHSLA
MLBr_01753|M.leprae_Br4923          CRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQTRALV
MAB_4771|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_5018|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               IKGQCNEAEQLADALIESAEATR------NPAALCYALLAYG--------
MUL_2743|M.ulcerans_Agy99           IKGQCDEAEQLADALIESAEATR------NPAALCYALLAYG--------
Mb2515c|M.bovis_AF2122/97           HRGDTEAA-AAAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHA
Rv2488c|M.tuberculosis_H37Rv        HRGDTEAA-AAAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHA
Mvan_5928|M.vanbaalenii_PYR-1       QRGDTDAARAAAQVSLNVAVEVSPVHAGLAHAALAVANLAAGDVTAAEAA
MLBr_01753|M.leprae_Br4923          HR-DVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAVEA
MAB_4771|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_5018|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               -------------FTFRDTNPASALAAMRRGLRIAQDTGNRNS-------
MUL_2743|M.ulcerans_Agy99           -------------FTFRDTNPASALAAMRRGLRIAQDTGNRNS-------
Mb2515c|M.bovis_AF2122/97           RESATRFFGASAAAIINDPTSSAQISCARGDLNAAHRLADGAASITRGVH
Rv2488c|M.tuberculosis_H37Rv        RESATRFFGASAAAIINDPTSSAQISCARGDLNAAHRLADGAASITRGVH
Mvan_5928|M.vanbaalenii_PYR-1       SDSATRSFGPSEVAGIQDPNVAAQIACTRGDLDTARSLVDGAVSITRGVH
MLBr_01753|M.leprae_Br4923          SEACRPHLGADHGLVAIHLELMAAVALARGDVIVARRLADNSVSATTGWH
MAB_4771|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_5018|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               ETHLAAVLCRVEAKYGDPLSALDYFTLAIHNHHEAGNTTLISTPLAVLAA
MUL_2743|M.ulcerans_Agy99           ETHLAAVLCRVEAKYGDPLSALDHFTLAIHNHHEAGNTTLISTPLAVLAA
Mb2515c|M.bovis_AF2122/97           RARALTTRCRIEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLAS
Rv2488c|M.tuberculosis_H37Rv        RARALTTRCRIEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLAS
Mvan_5928|M.vanbaalenii_PYR-1       RASALTTRARIAIAQGDPEQAERNAHDALSLAAGVGARLEVPDTLECLAR
MLBr_01753|M.leprae_Br4923          QMAALTTRARIAMAQGEPELARADIHAALACGADIQASLGISDSMELLAE
MAB_4771|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_5018|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               FFDRLGRYEAAATIAGFAFHPITEASFP-------ELRTTISHLRDALGD
MUL_2743|M.ulcerans_Agy99           FFDRLGRYEAAATIAGFAFHPITEASFP-------ELRTTISHLRDALGD
Mb2515c|M.bovis_AF2122/97           VMADAGSNREAVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGD
Rv2488c|M.tuberculosis_H37Rv        VMADAGSNREAVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGD
Mvan_5928|M.vanbaalenii_PYR-1       VVGDGGSHHEAARLCGAAEAIRGRTGAVRFRIYDADHETTVTTLRDALGD
MLBr_01753|M.leprae_Br4923          LISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLRGAMGC
MAB_4771|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_5018|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               HAYESFSQSGAAMTTAAMATYAYHQIDHARTELQAR--------------
MUL_2743|M.ulcerans_Agy99           HAYESFSQSGAAMTTAAMATYAYHQIDHARTEFQAR--------------
Mb2515c|M.bovis_AF2122/97           SEFDDAWAEGTALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVALLV
Rv2488c|M.tuberculosis_H37Rv        SEFDDAWAEGTALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVALLV
Mvan_5928|M.vanbaalenii_PYR-1       KAFEAAWTEGSATSITEAIAYAQRGRGERKRPSSGWASLTPTELDVVGLV
MLBr_01753|M.leprae_Br4923          KDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNVIRLV
MAB_4771|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_5018|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAV_1250|M.avium_104                --------------------------------------------------
TH_1244|M.thermoresistible__bu      --------------------------------------------------
Mflv_2091|M.gilvum_PYR-GCK          --------------------------------------------------
MMAR_3522|M.marinum_M               --------------------------------------------------
MUL_2743|M.ulcerans_Agy99           --------------------------------------------------
Mb2515c|M.bovis_AF2122/97           GEGLSNKEIGVRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESE
Rv2488c|M.tuberculosis_H37Rv        GEGLSNKEIGVRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESE
Mvan_5928|M.vanbaalenii_PYR-1       SEGLSNKDIAARLFVSPRTVQTHLTHVYTKLCLASRVQLAQEAARHT---
MLBr_01753|M.leprae_Br4923          SEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN---
MAB_4771|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_5018|M.smegmatis_MC2_155      --------------------------------------------------
                                                                                      

MAV_1250|M.avium_104                ------
TH_1244|M.thermoresistible__bu      ------
Mflv_2091|M.gilvum_PYR-GCK          ------
MMAR_3522|M.marinum_M               ------
MUL_2743|M.ulcerans_Agy99           ------
Mb2515c|M.bovis_AF2122/97           RGPSRP
Rv2488c|M.tuberculosis_H37Rv        RGPSRP
Mvan_5928|M.vanbaalenii_PYR-1       ------
MLBr_01753|M.leprae_Br4923          ------
MAB_4771|M.abscessus_ATCC_1997      ------
MSMEG_5018|M.smegmatis_MC2_155      ------