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MFEVEPPSVWHSALVAADLGGPPSGIVTFLFTDVEGSTRRWESDPDRMRAALAAHDAVLKRTIQTHRGWL FKHTGDGVCAAFASPRSAVDAAVDAQRALELPVRMGLATGEAEPHDADYFGAVLNRAARVMATGHGGQIL LTDSTANLISGVDLLDLGSRRLRDLPAPVRVFQVRAPGLRTDFPALRAPDTSPGNLRPALTSFVARAAEI GQVQTALQVHRLVTLTGVGGVGKTRLALEVATRVADEFPDGVWLFELAAVSDPAAVPDAVAAVLGITQQA GKSVTQSVATALEGRVRLSVFDNCEHVRDAAADLIEAILAGSTTVRILATSRERLEVPDEQLWSVPSLDV GGGVVSAAGTLFVERAQSVAPGFAPTDAQDAAAIAEICRRLDGIPLAIELAASRMASMTPIEVRDRLDHR FRLLVGSRRGLGRHQTLRHAVAWSYDHLSDAEKVLLERCSVFAGGFDLQSACAVAGSADTHDDYEVLDLL DALVGKSLLIVDRLSGRSRFSMLETIREFAEEQLVTRGQALAARTAHARHFAQRLPDVAAVWDSPRQPEA YTWLTAELANLRLAFRWTADNNDLDDAASIATWVGFLGFFVNRFEPLTWVEEAIERAVDHPKLAFLHVLA SQCYMTGRVQEAIRYADEAARLLATDRYEVPFGIEGWPSGAYTSSGHPEQSVELCRTQLALGRDTHTLTL GCLVLALTIKGQCNEAEQLADALIESAEATRNPAALCYALLAYGFTFRDTNPASALAAMRRGLRIAQDTG NRNSETHLAAVLCRVEAKYGDPLSALDYFTLAIHNHHEAGNTTLISTPLAVLAAFFDRLGRYEAAATIAG FAFHPITEASFPELRTTISHLRDALGDHAYESFSQSGAAMTTAAMATYAYHQIDHARTELQAR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_3522 | - | - | 100% (903) | LuxR family transcriptional regulator |
M. marinum M | MMAR_0123 | - | e-119 | 36.30% (843) | LuxR family transcriptional regulator |
M. marinum M | MMAR_2962 | - | 2e-92 | 37.60% (609) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2515c | - | 1e-110 | 41.98% (617) | LuxR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_2091 | - | 5e-15 | 34.46% (148) | putative adenylate/guanylate cyclase |
M. tuberculosis H37Rv | Rv2488c | - | 1e-110 | 41.98% (617) | LuxR family transcriptional regulator |
M. leprae Br4923 | MLBr_01753 | - | 6e-85 | 35.14% (700) | putative transcriptional regulator |
M. abscessus ATCC 19977 | MAB_4771 | - | 1e-11 | 35.71% (126) | putative adenylate cyclase |
M. avium 104 | MAV_1250 | - | 8e-15 | 33.33% (168) | adenylate and guanylate cyclase catalytic domain-containing |
M. smegmatis MC2 155 | MSMEG_5018 | - | 1e-12 | 31.29% (163) | adenylate and guanylate cyclase catalytic domain-containing |
M. thermoresistible (build 8) | TH_1244 | - | 4e-16 | 32.54% (169) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_2743 | - | 0.0 | 98.52% (877) | LuxR family transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_5928 | - | 1e-118 | 41.07% (655) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -------------------------------------------------- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M ------------------------------MFEVEPPSVWHSALVAADLG MUL_2743|M.ulcerans_Agy99 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE Rv2488c|M.tuberculosis_H37Rv MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE Mvan_5928|M.vanbaalenii_PYR-1 -----------------------------------------------MSE MLBr_01753|M.leprae_Br4923 ----------------MYSLGEMQKPVPVGADYLASCLVARLRSTDVPTD MAB_4771|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5018|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -------------------------------------------------- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M GPPSGIVTFLFTDVEGSTRRWESDPDRMRAALAAHDAVLKRTIQTHRGWL MUL_2743|M.ulcerans_Agy99 ------MTFLFTDVEGSTRLWESDPDRMRAALAAHDAVLTRTIQTHRGWL Mb2515c|M.bovis_AF2122/97 LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRGVC Rv2488c|M.tuberculosis_H37Rv LVPTGTVTLLLADIEGATHLPGSQLD--TTAIAKLDRTLTELVREHRGVC Mvan_5928|M.vanbaalenii_PYR-1 LVPTGTVTLLLADVQGSTQLWETQPETMTAAVAQLDRTLTDLVSDHDGVR MLBr_01753|M.leprae_Br4923 LHRGCTVTLFLGDVEGLAELSETQPDEAADAIARLDCVVSEAVAAHGGVQ MAB_4771|M.abscessus_ATCC_1997 ------------------------------------------MPESDELN MSMEG_5018|M.smegmatis_MC2_155 ----MVSQQVQPDIQPLLEGLDGAARSQREELINWLLSRGISVDQIGQAI MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -----------------------------VAARPLPLAVAAAPGSPIPR- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M FKHTGDG--VCAAFASPRSAVDAAVDAQRALELPVR--MGLATGEAEPH- MUL_2743|M.ulcerans_Agy99 FKHTGDG--VCAAFASPRSAVDAAVDAQRALELPVR--MGLATGEAEPH- Mb2515c|M.bovis_AF2122/97 PVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSP- Rv2488c|M.tuberculosis_H37Rv PVEQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSP- Mvan_5928|M.vanbaalenii_PYR-1 PVEQGEGDSFVVAFTRASDAVACALALQRAPLAPIRLRIGVHTGEVRLR- MLBr_01753|M.leprae_Br4923 QVVQGVRGNFLATFARASDATACALDLQLAPIVPVRFRIALHTGEVQISN MAB_4771|M.abscessus_ATCC_1997 AVVDAAVEQVLLGGPRRYTRSQVSQLSGVPVERARTLWVALGFAAADSD- MSMEG_5018|M.smegmatis_MC2_155 TPMLLASRRVAGDDGTYVSAREISEQTGLDLDLLQRLQRAMGLPAVEDP- MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -------------------------------------------------- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M -DADYFGAVLNRAARVMATGHGGQILLTDSTANLISGVD-----LLDLGS MUL_2743|M.ulcerans_Agy99 -DADYFGAVLNRAARVMATGHGGQILLTDSTANLISGVD-----LLDLGS Mb2515c|M.bovis_AF2122/97 DEGNCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGT Rv2488c|M.tuberculosis_H37Rv DEGNCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGT Mvan_5928|M.vanbaalenii_PYR-1 DEGNYVGPTINRTARLRELAHGGQTVLSGTTSDLVADLLPDGGWLSDLGT MLBr_01753|M.leprae_Br4923 DDVNNVVFMMVQAAGLLDLACGGQTVLSSITGDLVVDGLPADTWLVDLGS MAB_4771|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5018|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1250|M.avium_104 ----------MG-----DVLHVTVYILAGLAAVEAGALAVLWRRLVRSRA TH_1244|M.thermoresistible__bu ---------RVGQDGAVTQIAIVVVALAGLALAEAVALAVLWGRLRRERR Mflv_2091|M.gilvum_PYR-GCK -------------------MLILVCVLAVLAAGLGIALAVQTRRLTSARQ MMAR_3522|M.marinum_M RRLRDLPAPVRVFQVRAPGLRTDFPALRAPDTSPGN-LRPALTSFVARAA MUL_2743|M.ulcerans_Agy99 RRLRDLPAPVRVFQVRAPGLRTDFPALRAPDTSPGN-LRPALTSFVARAA Mb2515c|M.bovis_AF2122/97 YRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVD Rv2488c|M.tuberculosis_H37Rv YRLDDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVD Mvan_5928|M.vanbaalenii_PYR-1 HRLRDLPRPERVVQLCHADLSNEFPPLRAREEIGVQRLPAQLTSFVGRVD MLBr_01753|M.leprae_Br4923 HLLRDLARPVRVMQLCHRNLRRNLHELGIRTVPGGPSLPVPLTTFVGRAA MAB_4771|M.abscessus_ATCC_1997 --------DEVAFTDADVSAIRTFAALGSATAANQQSQIAAARTLGQAMA MSMEG_5018|M.smegmatis_MC2_155 ---------DAAVLLRADAEAVTFSQQFIDLGIDADQVVLITRVLAEGLS . : MAV_1250|M.avium_104 ELDELRQRTDARNWLLAGGREAVKTVWNTANLVRKEGFG--AAVRSSIEE TH_1244|M.thermoresistible__bu AADELRRRLDTRTTLMAGGREAVRTVWQTANILRTDGLG--AAARSSIED Mflv_2091|M.gilvum_PYR-GCK EAEELRHRLDTRQLLVSGGTKAVKTVWQTANILRKDGFG--AAVRSSIEE MMAR_3522|M.marinum_M EIGQVQTALQVHRLVTLTGVGGVGKTRLALEVATRVADE--FPDGVWLFE MUL_2743|M.ulcerans_Agy99 EIGQVQTALQVHRLVTLTGVGGVGKTRLALEVATRVADE--FPDGVWLFE Mb2515c|M.bovis_AF2122/97 EVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADG--YPDGVWYVN Rv2488c|M.tuberculosis_H37Rv EVAQVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADG--YPDGVWYVN Mvan_5928|M.vanbaalenii_PYR-1 DMAQVRGLMDANRLVTLTGAGGVGKTRLATQVAVAVVEG--YPGGVWYVD MLBr_01753|M.leprae_Br4923 QIKELQELLTEKRLLTLVGPGGVGKTRLALQVVARVADE--FSGELSYFD MAB_4771|M.abscessus_ATCC_1997 RLAEWQADLLTREVGGRLAAEGDDASAESSANAATQTIA--TLTALQNYA MSMEG_5018|M.smegmatis_MC2_155 RAAEVMRAAALAAVLEPGASELETAKAAEGLVAEAAPLLGPMIQDMLFVQ : . MAV_1250|M.avium_104 LADWAEVERP--------------------DLARVTPDGRVVILFTDIEE TH_1244|M.thermoresistible__bu LADWAEVERP--------------------DLARLAANGKVVILFSDIEG Mflv_2091|M.gilvum_PYR-GCK LADWAEVERP--------------------DLARLSLNGRLTIMFSDIEE MMAR_3522|M.marinum_M LAAVSDPAAVPDAVAAVLGITQQAGKSVTQSVATALEGRVRLSVFDNCEH MUL_2743|M.ulcerans_Agy99 LAAVSDPAAVPDAVAAVLGITQQAGKTVTQSVATALERRVRLLVFDNCEH Mb2515c|M.bovis_AF2122/97 LAPITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEH Rv2488c|M.tuberculosis_H37Rv LAPITDPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEH Mvan_5928|M.vanbaalenii_PYR-1 LAPITDPALVAITVARALGLPDQPGRSTVDTIVRFIADRRMLVVLDNCEH MLBr_01753|M.leprae_Br4923 LAPDTDHDIFPITVL--------------DNLRRCIGDRRMLMVLDNCEY MAB_4771|M.abscessus_ATCC_1997 WQRHLAAALHR-------------------ANETGSTTRQLLVGFADMVG MSMEG_5018|M.smegmatis_MC2_155 LRHAMETEAVDASER--------------AEGVPLPGARLVTVAFADIVG : : MAV_1250|M.avium_104 S-----TALNERIGDRAWVKLISS-------------------------- TH_1244|M.thermoresistible__bu S-----TALNNRIGDRAWVRLIDR-------------------------- Mflv_2091|M.gilvum_PYR-GCK S-----TALNERIGDRAFVRLIGR-------------------------- MMAR_3522|M.marinum_M VRDAAADLIEAILAGSTTVRILATSRERLEVPDEQLWSVPSLDVGGGVVS MUL_2743|M.ulcerans_Agy99 VRDAAADLIEAILAGSTTVRILATSRERLEVPDEQLWSVPSLDVGGGVVS Mb2515c|M.bovis_AF2122/97 LLDGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLGHG----- Rv2488c|M.tuberculosis_H37Rv LLDGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLGHG----- Mvan_5928|M.vanbaalenii_PYR-1 LLDACATLIDALLGACPALAMLATSREPIAVAGEQTWRVPPLALDD---- MLBr_01753|M.leprae_Br4923 LLDVCANVMTTLLGACPSLTILATSREPIGVAGEVIWRVSMLSPAD---- MAB_4771|M.abscessus_ATCC_1997 Y-----TRLSRHLDPDELASLLET-------------------------- MSMEG_5018|M.smegmatis_MC2_155 F-----TRLGEVVPPEQLEQLANS-------------------------- : : : MAV_1250|M.avium_104 -----------------------HDKLVSDLVRRQSGH------------ TH_1244|M.thermoresistible__bu -----------------------HSRLVRRFVKKHDGY------------ Mflv_2091|M.gilvum_PYR-GCK -----------------------HDKSVRKFVDKHEGH------------ MMAR_3522|M.marinum_M AAGTLFVERAQSVAPGFAPTDAQDAAAIAEICRRLDGIPLAIELAASRMA MUL_2743|M.ulcerans_Agy99 AAGTLFVERAQSVAPGFAPTDAQDAAAIGEICRRLDGIPLAIELAASRMA Mb2515c|M.bovis_AF2122/97 EAIELFTDRAREARPELEIT-ADNLALVTEICHRLDGIPLAIELAASRVR Rv2488c|M.tuberculosis_H37Rv EAIELFTDRAREARPELEIT-ADNLALVTEICHRLDGIPLAIELAASRVR Mvan_5928|M.vanbaalenii_PYR-1 DAIELFTDRARRARPDFIIS-ADDAAAVSEICHRLDGMPLAIELAAARVR MLBr_01753|M.leprae_Br4923 EAVELFTERAALVQPGFSVT-DGNRQIVTEICQRLDGMPLAIELAAARIR MAB_4771|M.abscessus_ATCC_1997 -----------------------FETALTEAITTHGGW------------ MSMEG_5018|M.smegmatis_MC2_155 -----------------------LAEATRDVVRP---------------- MAV_1250|M.avium_104 ------VVKSQGDGFMVAFARPEQAVRCGIELQRALRR------------ TH_1244|M.thermoresistible__bu ------VIKSQGDGFMVAFARPEQAVRCSVELQRALR------------- Mflv_2091|M.gilvum_PYR-GCK ------VVKSQGDGFMVAFAKPEQAVRCGLDIQHSLA------------- MMAR_3522|M.marinum_M SMTPIEVRDRLDHRFRLLVG-SRRGLGRHQTLRHAVAWSYDHLSDAEKVL MUL_2743|M.ulcerans_Agy99 SMTPIEVRDRLDHRFRLLVG-SRRGLGRHQTLRHAVAWSYDHLSDAEKVL Mb2515c|M.bovis_AF2122/97 ALALTEIVDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVL Rv2488c|M.tuberculosis_H37Rv ALALTEIVDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVL Mvan_5928|M.vanbaalenii_PYR-1 ALSLTEIVDGLHDRFRLLTGGSRTAVRRQQTLRASVDWSHGLLTDPERVL MLBr_01753|M.leprae_Br4923 TLSLTEIADGLDDRFRLLTGGARTAVRRQQTLRASMDWSYALLTESERAL MAB_4771|M.abscessus_ATCC_1997 ------VIKNVGDEVMFAAASAAAGARIAVAMNTAIT------------- MSMEG_5018|M.smegmatis_MC2_155 ---PVRLIKTIGDAVMLVSPEPAALLDAVLNLVAATE------------- : . . . . . : : MAV_1250|M.avium_104 ---------------------NANRKRHEEIRVRIGIHMGRSVRRGDDLF TH_1244|M.thermoresistible__bu -------------------------KRPDRIRVRIGIHLGRSVRRGDDLF Mflv_2091|M.gilvum_PYR-GCK -------------------------RRPNDIRVRMGVHTGKSVLRGDDVF MMAR_3522|M.marinum_M LERCSVFAGGFDLQSACAVAGSADTHDDYEVLDLLDALVGKSLLIVDRLS MUL_2743|M.ulcerans_Agy99 LERCSVFAGGFDLQSACAVAGSADTHDDYEVLDLLDALVGKSLLIVDRLS Mb2515c|M.bovis_AF2122/97 FRRLAVFPSGFDLDGAQAAA-AGGDVQRYEVVDLLSLLADKSLVVTDDSD Rv2488c|M.tuberculosis_H37Rv FRRLAVFPSGFDLDGAQAAA-AGGDVQRYEVVDLLSLLADKSLVVTDDSD Mvan_5928|M.vanbaalenii_PYR-1 FRRLAVFAGGFDLDGAQAIT-VDGEVHRYEVVDLLTLLVDKSLLIAENTA MLBr_01753|M.leprae_Br4923 FRRLSAISGTFDLKVAYAVG-HDDLEEPDQVFDRLTMLIDKSLVIVEGRQ MAB_4771|M.abscessus_ATCC_1997 ---------------------EAAQTIPDMPQIRVGLAYGQVLSRFGDLY MSMEG_5018|M.smegmatis_MC2_155 -------------------------ADPEFPGLRVGLATGMAVSRAGDWF : . : MAV_1250|M.avium_104 GRNVAMAARVAAQAAGGEILVSQPVRDALSRS--------DGIRFD---- TH_1244|M.thermoresistible__bu GRNVALAARVAGAAEGGEVLVSQAVRDALNSAGDAGSDEVAGFDVD---- Mflv_2091|M.gilvum_PYR-GCK GRNVAMAARVAAAADGGEILVSSAVHRALADC--------EDLAFD---- MMAR_3522|M.marinum_M GRSRFSMLETIREFAEEQLVTRGQALAARTAHARHFAQRLPDVAAVWDSP MUL_2743|M.ulcerans_Agy99 GRSRFSMLETIREFAEEQLVTRGQALAARTAHARHFAQRLPDVAAVWDSP Mb2515c|M.bovis_AF2122/97 GRTRYRLLETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAG Rv2488c|M.tuberculosis_H37Rv GRTRYRLLETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAG Mvan_5928|M.vanbaalenii_PYR-1 GRTRYRLLETVRQYAQEKLGESGEADTLRARHRDHYTARAAELDAPSVAG MLBr_01753|M.leprae_Br4923 GGSRYRLLETVRQYAMKKLEESNEVDLVLARHRDHYMALGALLDTPGDID MAB_4771|M.abscessus_ATCC_1997 GTVVNIAARLTGVARPGTILLDDGAAAALGDD--------GEFSLR---- MSMEG_5018|M.smegmatis_MC2_155 GSPVNLASRVTGVARPGTVLVAESTRQAIAAAD-------DRFRWS---- * . : . . MAV_1250|M.avium_104 ------DGREVELKGFSGTYRLFAVLAS----PDPG-------------- TH_1244|M.thermoresistible__bu ------DGREVSLKGFPGRHRLFAVRGQAGFRPRPRPE------------ Mflv_2091|M.gilvum_PYR-GCK ------EQRDVELKGFSGSHTLYPVRSA----SASR-------------- MMAR_3522|M.marinum_M RQPEAYTWLTAELANLRLAFRWTADNNDLDDAASIATWVGFLGFFVNRFE MUL_2743|M.ulcerans_Agy99 RQPEAYTWLTAELANLRLAFRWTADNNDLDDAASIATWVGFLGFLVNRFE Mb2515c|M.bovis_AF2122/97 -HERRLNQAELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQ Rv2488c|M.tuberculosis_H37Rv -HERRLNQAELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQ Mvan_5928|M.vanbaalenii_PYR-1 -HERRLNQTDIEMDNLRAAFAWSRENANTDHSLLLASSLHPLWRARGRLQ MLBr_01753|M.leprae_Br4923 -HEQLVEQVETELDNLRSAFAWSRETGDIAGALQLASSLQPIWFGRGHMY MAB_4771|M.abscessus_ATCC_1997 ------HLRGVRVKGFSRLGSHVLRARKR--------------------- MSMEG_5018|M.smegmatis_MC2_155 ------FAGARRLKGIKGDVKMFRARMRDQ-------------------- : .: MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -------------------------------------------------- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M P-LTWVEEAIERAVDHPKLAFLHVLASQCYMTGRVQEAIR---------- MUL_2743|M.ulcerans_Agy99 P-LTWVEEAIERAVDHPKLAFLHVLASQCYTTGRVQEAIR---------- Mb2515c|M.bovis_AF2122/97 EGLAWFAAALADHDAHPAGADPGLYARALADRALIDAVAG-----ITDRL Rv2488c|M.tuberculosis_H37Rv EGLAWFAAALADHDAHPAGADPGLYARALADRALIDAVAG-----ITDRL Mvan_5928|M.vanbaalenii_PYR-1 EGQAWFDAALTDYEARPGEADPAVYARALADRAFMDGHVG-----ITDRL MLBr_01753|M.leprae_Br4923 EGLAWFDSIFEHKNIEHLVAPKEVLARAVANKVMLHAILASSPPDGSDLV MAB_4771|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5018|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -------------------------------------------------- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M -------------------------------YADEAARLLATDRYEVP-- MUL_2743|M.ulcerans_Agy99 -------------------------------YADEAARLLATDRYEVP-- Mb2515c|M.bovis_AF2122/97 DDAQKALAIARDIEDPALLARALTACGGVAAYNADLARPWLAEAVGLARA Rv2488c|M.tuberculosis_H37Rv DDAQKALAIARDIEDPALLARALTACGGVAAYNADLARPWLAEAVGLARA Mvan_5928|M.vanbaalenii_PYR-1 DQAQKALAMARDIDDPALLVRALTACGGLAAYNADVARPLLAEAVDLARS MLBr_01753|M.leprae_Br4923 TQAQQALTMAREIGDSAVLARALTACGFSSGYDTEVARPYFAEAVELART MAB_4771|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5018|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -------------------------------------------------- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M ------------------FGIEGWPSGAYTS------------------- MUL_2743|M.ulcerans_Agy99 ------------------FGIEGWPSGACTS------------------- Mb2515c|M.bovis_AF2122/97 VGDKWRLAEVLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRS Rv2488c|M.tuberculosis_H37Rv VGDKWRLAEVLAWQAYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRS Mvan_5928|M.vanbaalenii_PYR-1 MGDKWMLAETLAWQAYAALMGGGDPVAARTAGEEARELADEMGDGFVSRI MLBr_01753|M.leprae_Br4923 QGDKWTLSQIRLWG-VVGFCVSGDPVALRAAAEAADDLAQEIGDRFVSLQ MAB_4771|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5018|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -------------------------------------------------- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M -----------SGHPEQSVELCR-----TQLALGRDTHTLTLGCLVLALT MUL_2743|M.ulcerans_Agy99 -----------SGHPEQSVELCR-----TQLALGHDTHTLTLGCLVLALT Mb2515c|M.bovis_AF2122/97 CRWALAAANLWQGNLEAAVGLSREVIGESDAAHDMVSSCAGQACLAHALA Rv2488c|M.tuberculosis_H37Rv CRWALAAANLWQGNLEAAVGLSREVIGESDAAHDMVSSCAGQACLAHALA Mvan_5928|M.vanbaalenii_PYR-1 CGWLLGIAHHFQGDLDAALALADGVVSESDVAHDTLNGCCGELVLAHSLA MLBr_01753|M.leprae_Br4923 CRLLLSIAQLWQGDMDGAIVRSGEVVAGAEAAHDTVTRTFGLYVQTRALV MAB_4771|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5018|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -------------------------------------------------- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M IKGQCNEAEQLADALIESAEATR------NPAALCYALLAYG-------- MUL_2743|M.ulcerans_Agy99 IKGQCDEAEQLADALIESAEATR------NPAALCYALLAYG-------- Mb2515c|M.bovis_AF2122/97 HRGDTEAA-AAAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHA Rv2488c|M.tuberculosis_H37Rv HRGDTEAA-AAAQASIDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHA Mvan_5928|M.vanbaalenii_PYR-1 QRGDTDAARAAAQVSLNVAVEVSPVHAGLAHAALAVANLAAGDVTAAEAA MLBr_01753|M.leprae_Br4923 HR-DVSAALVTAGLVVEAAAELSGVYQGIGYAAMVFAALAMGDVAAAVEA MAB_4771|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5018|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -------------------------------------------------- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M -------------FTFRDTNPASALAAMRRGLRIAQDTGNRNS------- MUL_2743|M.ulcerans_Agy99 -------------FTFRDTNPASALAAMRRGLRIAQDTGNRNS------- Mb2515c|M.bovis_AF2122/97 RESATRFFGASAAAIINDPTSSAQISCARGDLNAAHRLADGAASITRGVH Rv2488c|M.tuberculosis_H37Rv RESATRFFGASAAAIINDPTSSAQISCARGDLNAAHRLADGAASITRGVH Mvan_5928|M.vanbaalenii_PYR-1 SDSATRSFGPSEVAGIQDPNVAAQIACTRGDLDTARSLVDGAVSITRGVH MLBr_01753|M.leprae_Br4923 SEACRPHLGADHGLVAIHLELMAAVALARGDVIVARRLADNSVSATTGWH MAB_4771|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5018|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -------------------------------------------------- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M ETHLAAVLCRVEAKYGDPLSALDYFTLAIHNHHEAGNTTLISTPLAVLAA MUL_2743|M.ulcerans_Agy99 ETHLAAVLCRVEAKYGDPLSALDHFTLAIHNHHEAGNTTLISTPLAVLAA Mb2515c|M.bovis_AF2122/97 RARALTTRCRIEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLAS Rv2488c|M.tuberculosis_H37Rv RARALTTRCRIEIAQGDRHRAERDAHDALGVAASIGAYLWVPDILECLAS Mvan_5928|M.vanbaalenii_PYR-1 RASALTTRARIAIAQGDPEQAERNAHDALSLAAGVGARLEVPDTLECLAR MLBr_01753|M.leprae_Br4923 QMAALTTRARIAMAQGEPELARADIHAALACGADIQASLGISDSMELLAE MAB_4771|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5018|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -------------------------------------------------- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M FFDRLGRYEAAATIAGFAFHPITEASFP-------ELRTTISHLRDALGD MUL_2743|M.ulcerans_Agy99 FFDRLGRYEAAATIAGFAFHPITEASFP-------ELRTTISHLRDALGD Mb2515c|M.bovis_AF2122/97 VMADAGSNREAVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGD Rv2488c|M.tuberculosis_H37Rv VMADAGSNREAVRLFGAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGD Mvan_5928|M.vanbaalenii_PYR-1 VVGDGGSHHEAARLCGAAEAIRGRTGAVRFRIYDADHETTVTTLRDALGD MLBr_01753|M.leprae_Br4923 LISQGDNHRQAGRLFGAASAQREKTGEVRFKVWDAGYESAVAVLRGAMGC MAB_4771|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5018|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -------------------------------------------------- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M HAYESFSQSGAAMTTAAMATYAYHQIDHARTELQAR-------------- MUL_2743|M.ulcerans_Agy99 HAYESFSQSGAAMTTAAMATYAYHQIDHARTEFQAR-------------- Mb2515c|M.bovis_AF2122/97 SEFDDAWAEGTALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVALLV Rv2488c|M.tuberculosis_H37Rv SEFDDAWAEGTALSIDEAIAYAQRGRGARKRPTSGWGALTPTELEVALLV Mvan_5928|M.vanbaalenii_PYR-1 KAFEAAWTEGSATSITEAIAYAQRGRGERKRPSSGWASLTPTELDVVGLV MLBr_01753|M.leprae_Br4923 KDFDSAWAEGAAMPIDDAITYAQRGRGNRKRPTTGWESLTPAEHNVIRLV MAB_4771|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5018|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1250|M.avium_104 -------------------------------------------------- TH_1244|M.thermoresistible__bu -------------------------------------------------- Mflv_2091|M.gilvum_PYR-GCK -------------------------------------------------- MMAR_3522|M.marinum_M -------------------------------------------------- MUL_2743|M.ulcerans_Agy99 -------------------------------------------------- Mb2515c|M.bovis_AF2122/97 GEGLSNKEIGVRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESE Rv2488c|M.tuberculosis_H37Rv GEGLSNKEIGVRLFISPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESE Mvan_5928|M.vanbaalenii_PYR-1 SEGLSNKDIAARLFVSPRTVQTHLTHVYTKLCLASRVQLAQEAARHT--- MLBr_01753|M.leprae_Br4923 SEGLDTKDIAARLFVSVRTVHTHLTRIYSKLGLTSRVQLVQEAARHN--- MAB_4771|M.abscessus_ATCC_1997 -------------------------------------------------- MSMEG_5018|M.smegmatis_MC2_155 -------------------------------------------------- MAV_1250|M.avium_104 ------ TH_1244|M.thermoresistible__bu ------ Mflv_2091|M.gilvum_PYR-GCK ------ MMAR_3522|M.marinum_M ------ MUL_2743|M.ulcerans_Agy99 ------ Mb2515c|M.bovis_AF2122/97 RGPSRP Rv2488c|M.tuberculosis_H37Rv RGPSRP Mvan_5928|M.vanbaalenii_PYR-1 ------ MLBr_01753|M.leprae_Br4923 ------ MAB_4771|M.abscessus_ATCC_1997 ------ MSMEG_5018|M.smegmatis_MC2_155 ------