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M. marinum M MMAR_2806 (-)

annotation: PPE family protein
coordinates: 3406422 - 3407663
length: 413

TSPLWMASPPEVHSSLLSTGPGPGGILVAAAGWLSLGALFEATAAEVDHQICEAIRLWQGRAADDYVAAH
TPYVVWLDHAAIVCQRAGAALQMMVAAYSDALAEMPTMAELQENHAVHGVLVATNFFGLNGVPIAVNEAD
YVRMWIQAAGVMGVYESCTSAALLEVPPTSPSPVLVNPGVEGVGNATSWSGFADSDEFSVSSFNDGVLGL
DVAGELCEFDPFDGLDLDGCQLVSVSTTQGFGAAMDVTAAPGSPLSGAALAPTGHICAGVPLATSTPLGV
TRHVGDLQMMAARDNSDRTVVDAPHEILVSDSRGGTAQSGASGSVRPGVGSASVVQAASDGRPVSELAGG
RGAGTVGFAGVSATGTKVRPAGLSATGGGEFGSGAGVPVLPATWPLQVVGSTSGSGVSPPAL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_2806--100% (413)PPE family protein
M. marinum MMMAR_3002-2e-8041.69% (427) PPE family protein
M. marinum MMMAR_3006-1e-6138.86% (404) PPE family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3047cPPE473e-6336.20% (442) PPE family protein
M. gilvum PYR-GCKMflv_0325-1e-4949.24% (197) PPE protein
M. tuberculosis H37RvRv3018cPPE461e-6235.51% (445) PPE family protein
M. leprae Br4923MLBr_01828PPE4e-4145.51% (178) PPE-family protein
M. abscessus ATCC 19977MAB_0669-7e-5732.69% (465) PPE-family protein
M. avium 104MAV_2429-3e-5536.57% (402) PPE family protein
M. smegmatis MC2 155MSMEG_0619-3e-5453.40% (191) PPE family protein
M. thermoresistible (build 8)TH_3569-3e-5050.00% (188) PUTATIVE PPE protein
M. ulcerans Agy99MUL_2932-0.098.31% (415) PPE family protein
M. vanbaalenii PYR-1Mvan_0415-3e-5235.53% (425) PPE protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0325|M.gilvum_PYR-GCK          MTSPVASLAPVTSPVWMALPPEVHSTMLSSGPGPGSLLAAGVAWQSLSAE
Mvan_0415|M.vanbaalenii_PYR-1       ----------MSSPVWMALPPEVHSALLSSGPGPGSMLAAAATWQSLSAE
MSMEG_0619|M.smegmatis_MC2_155      ----------MTAPIWMALPPEVHSSLLSSGPGPGSLLAAAGAWQSLSAE
TH_3569|M.thermoresistible__bu      ---------MMTAPIWMALPPEVHSALLSSGPGPGSLLAAASAWHALSAE
MAV_2429|M.avium_104                ----------MTAPVWIAFPPEVHSTLLSSGPGPAPLLAAATAWSSMSTE
MLBr_01828|M.leprae_Br4923          ----------MSAPIWMASPPEVHSALLSRGPGSGPLLVAAEAWRSLSSV
MAB_0669|M.abscessus_ATCC_1997      ----------MTAPIWMAEPPEVHSALLSAGPGPGAVLAAAVQWQEIGNN
Mb3047c|M.bovis_AF2122/97           ----------MTAPVWLASPPEVHSALLSAGPGPGSLQAAAAGWSALSAE
Rv3018c|M.tuberculosis_H37Rv        ----------MTAPVWLASPPEVHSALLSAGPGPGSLQAAAAGWSALSAE
MMAR_2806|M.marinum_M               ----------MTSPLWMASPPEVHSSLLSTGPGPGGILVAAAGWLSLGAL
MUL_2932|M.ulcerans_Agy99           ----------MTSPLWMASPPEVHSSLLSTGPGPGGILVAAAGWLSLGAL
                                              :::*:*:* ******::** ***.. : .*.  *  :.  

Mflv_0325|M.gilvum_PYR-GCK          YASAAAELTSILAGVQSGAWEGPSSQQYVAAHTPYLAWLAQQSAVSAATA
Mvan_0415|M.vanbaalenii_PYR-1       YAAAAAELSSILADVQAGAWEGPSSEQYVAAHTPYLAWLAQQSAAGAAAA
MSMEG_0619|M.smegmatis_MC2_155      YAAAAAELTSVLSAVQAGSWEGPSSEQYVAAHAPYLQWLAQQSANSAAAA
TH_3569|M.thermoresistible__bu      YASAAAELSSVLANVQAGSWEGPSAERYVAAHAPYLAWLTQQSANSAATA
MAV_2429|M.avium_104                YAAAAAELDGLLAAAHAGAWEGPSAEQYVAAHAPYQAWLLESAAKSSTAA
MLBr_01828|M.leprae_Br4923          YAEMADELVALLVVVPVSSWDGSAAEAYVIAYLPYLGWLRQASVDSAVMA
MAB_0669|M.abscessus_ATCC_1997      YANTAVELAQVLAGVRAGSWQGPSASEYVAAHLPYLAWLEQAAAESSVIA
Mb3047c|M.bovis_AF2122/97           YAAVAQELSAVVAAVGAGVWQGPSAELFVAAYVPYVAWLVQASADSAAAA
Rv3018c|M.tuberculosis_H37Rv        YAAVAQELSVVVAAVGAGVWQGPSAELFVAAYVPYVAWLVQASADSAAAA
MMAR_2806|M.marinum_M               FEATAAEVDHQICEAIR-LWQGRAADDYVAAHTPYVVWLDHAAIVCQRAG
MUL_2932|M.ulcerans_Agy99           FEATAAEVDHQICEAIR-LWQGRAADDYVAAHTPYVVWLDHAAIVCQRAG
                                    :   * *:   :  .    *:* ::. :* *: **  ** . :      .

Mflv_0325|M.gilvum_PYR-GCK          VQHDTAAAAYTTALATMPTLPELALNHTTHAVLVGTNFLGINTIPIALNE
Mvan_0415|M.vanbaalenii_PYR-1       AQHEAAAAAYSTALATMPTLPELALNHTTHAVLVATNFLGINTIPIAMTE
MSMEG_0619|M.smegmatis_MC2_155      VQHETAAAAYSTALATMPTMAELALNHTMHGVLVATNFFGINTIPIALNE
TH_3569|M.thermoresistible__bu      GRHETAAAAYSTALATMPTMAELTLNKTTHAVLVATNFLGINTIPIALNE
MAV_2429|M.avium_104                SLHETAAGAYTAALAAMPTLGELATNHAVHGALVATNFFGINTIPIAVNE
MLBr_01828|M.leprae_Br4923          AHYETMATAYITTLAMMPTLAELAANRTAHTVLVTTNFFGINTIPIARNE
MAB_0669|M.abscessus_ATCC_1997      AQHETTAAAYNSALAAMPTLAELAANHITHGVLVGTNFFGINTIPIALNE
Mb3047c|M.bovis_AF2122/97           GEHEAAAAGYVCALAEMPTLPELAANHLTHAVLVATNFFGINTIPIALNE
Rv3018c|M.tuberculosis_H37Rv        GEHEAAAAGYVCALAEMPTLPELAANHLTHAVLVATNFFGINTIPIALNE
MMAR_2806|M.marinum_M               AALQMMVAAYSDALAEMPTMAELQENHAVHGVLVATNFFGLNGVPIAVNE
MUL_2932|M.ulcerans_Agy99           AALQMMVAAYGDALAEMPTMAELQENHAVHGVLVATNFFGLNGVPIAVNE
                                       :  . .*  :** ***: **  *:  * .** ***:*:* :*** .*

Mflv_0325|M.gilvum_PYR-GCK          ADYVRMWIQAATTMATYQSVSGAALAATPTSAPAPSVLLPGVGEAGRAAA
Mvan_0415|M.vanbaalenii_PYR-1       ADYVRMWIQAATTMATYQAVSGAALAATPTATPAPFVLAPGVGEAGRAAA
MSMEG_0619|M.smegmatis_MC2_155      ADYVRMWIQAATTMSTYQAVSGAAVAAAPVSAPAPFLLKPGVGEAGSASA
TH_3569|M.thermoresistible__bu      ADYVRMWIQAATSMSTYQAVAGTAVMSAPASSPAPLLLAPGVSEAADAMA
MAV_2429|M.avium_104                ADYARMWVQAATTMSTYQAVSQSALAAVPPTTPAPTIVAPGT-EAGTATA
MLBr_01828|M.leprae_Br4923          IDYVRMWVEAAIAMGTYQEVSTVVVDSAPEAIAAPQIMASDALEASSDQP
MAB_0669|M.abscessus_ATCC_1997      ADYVRMWVQAAATMSAYQATTEAMTSAIPPTQQPPAILSPGGEARSDQSD
Mb3047c|M.bovis_AF2122/97           ADYVRMWVQAATVMSAYEAVVGAALVATPHTGPAPVIVKPGANEASNAVA
Rv3018c|M.tuberculosis_H37Rv        ADYVRMWVQAATVMSAYEAVVGAALVATPHTGPAPVIVKPGANEASNAVA
MMAR_2806|M.marinum_M               ADYVRMWIQAAGVMGVYESCTSAALLEVPPTSPSPVLVNPGVEGVGNATS
MUL_2932|M.ulcerans_Agy99           ADYVRMWIQAAGVMGVYESCTSAALLEVRPTCPSPVLVNPGVEGVGNATS
                                     **.***::**  *..*:            :  .* :: ..    .    

Mflv_0325|M.gilvum_PYR-GCK          DMSAFAAQPMAAQA--------GAAFDVSNIIADIIRLY--GEVLR---F
Mvan_0415|M.vanbaalenii_PYR-1       DVTAFAAQAQAAEA--------GSALDLSNIIADLIRAY--GELLR---F
MSMEG_0619|M.smegmatis_MC2_155      SVQQMSAQATAAES--------GSSLDLSSIISDLLNQY--LQGVP---G
TH_3569|M.thermoresistible__bu      TTQQIGSQATAADS--------GTALNLSDLIANLLQYY--QDYLD---Q
MAV_2429|M.avium_104                AAVQSAAAAPATDS--------GSNLNHADTSSTQQQASTAAQSYP---S
MLBr_01828|M.leprae_Br4923          SPTAPSQSP-QVQNWLQWLQKIGYTDFYNTLVQPLITSLTNHPFFQGMFS
MAB_0669|M.abscessus_ATCC_1997      VPGSPDQIMKMLQGFQQWFEKMGFNPATSAVLAVIMLFLYDLLWYP----
Mb3047c|M.bovis_AF2122/97           AATIT-------------------PFPFGELAKFLEMAAQAFTEVG----
Rv3018c|M.tuberculosis_H37Rv        AATIT-------------------PFPWHEIVQFLEETFAAYDQYL----
MMAR_2806|M.marinum_M               WSGFADSDEFSVSS---------FNDGVLGLD--VAGELCEFDPFDG---
MUL_2932|M.ulcerans_Agy99           WSGFADSDEFSVSS---------FNDGVLGLDVAVAGELCEFDPFDG---
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          LFEPIFNFLRDPIGNTFALITDFLTN------PVQALITWGPFLLAVVYQ
Mvan_0415|M.vanbaalenii_PYR-1       LFEPIFDFLRDPLGNTIKLITDFLTN------PAQALITWGPFLAAVAYQ
MSMEG_0619|M.smegmatis_MC2_155      GQ-AILDFLKDPLGNLGRLLTDFMTN------PAGALATWWPFLFGVAYQ
TH_3569|M.thermoresistible__bu      LFGPIVDFLRDPIGNLFQLIDDFLTN------PAGALVTWWPLLFAVAYQ
MAV_2429|M.avium_104                WQDQLTAWLKQYTQNFAWPVSKDLNPGGWPFPPVPFVNGLASFFGQLGFS
MLBr_01828|M.leprae_Br4923          GFDPWLPSLGNPLSFLSPFNIAFALGTPMDIGSYVGYLSQTFAFIGADLA
MAB_0669|M.abscessus_ATCC_1997      ----------YYASYLLPFLIPALSG----LSGLAALMHLRPAAPGPVPA
Mb3047c|M.bovis_AF2122/97           ------ELIMKSAEAWAVGFVELITG----------LVNFEPWLVLTGMI
Rv3018c|M.tuberculosis_H37Rv        ------SALLSELPAVAWVWFQLFVD----------ILGFNIIGFIITLA
MMAR_2806|M.marinum_M               ----------LDLDGCQLVSVSTTQG------------------FGAAMD
MUL_2932|M.ulcerans_Agy99           ----------LDLDGCQLVSVSTTQG------------------FGAAMD
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          -AVSWVGA------------SILYPSLFLLPLLATTLAIVAGVGQHLLSL
Mvan_0415|M.vanbaalenii_PYR-1       -AVSWVGA------------SILYPSLLLLPLVATTLAIVLGVGAYLLEN
MSMEG_0619|M.smegmatis_MC2_155      -VFFNLVG------------WPTWGMIFASPFLIPALAALGITGLVLLID
TH_3569|M.thermoresistible__bu      -VFTNLVG------------WPTWAMILASPVLIPLAITLGVAGLVMIAD
MAV_2429|M.avium_104                PALSTALG------------WAIFHTLMIFWPFMQAAIQMAVVLAPVVVA
MLBr_01828|M.leprae_Br4923          AAFASGNPVTIGFTLLFTTIEAIGTIITDTIALVKTMIEQSFVLLPMILP
MAB_0669|M.abscessus_ATCC_1997      AALSPGD---------------------RPIRRPTQHVEPNLAALP----
Mb3047c|M.bovis_AF2122/97           DMFFATVG------------FALGVFVLVPLLEFAVVLELAILSIGWIIS
Rv3018c|M.tuberculosis_H37Rv        SNAQLLTE------------FAINASYVAVGLLYAIAGVIDIV-VEWVIG
MMAR_2806|M.marinum_M               VTAAPGSPLSG--------AALAPTGHICAGVPLATSTPLGVT-------
MUL_2932|M.ulcerans_Agy99           VTAAPGSPLSG--------AALAPTGHICAGVPLATSTPLGVT-------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          LNTP-PAEEAAEEPAPAQSAPSRPDQQSFPATMSAPPPPSGAPIAANTVS
Mvan_0415|M.vanbaalenii_PYR-1       LPAP-AEDAPAEEPAASSPAPTRADQPSPAIAVSAPPPPSSAAATVGTVA
MSMEG_0619|M.smegmatis_MC2_155      HVLNNPVDVPAEDEAPQEVAAAPRTDQPLAVGISPAGVPGSAATAAAPAP
TH_3569|M.thermoresistible__bu      QAQP-----PAEEAAPEEDVAAP-------------------VRAEPQNP
MAV_2429|M.avium_104                AIGAAAAGGAAAAVTAISVAAPLSMAAPVPVAAAPAPVATVPAPTIAGAP
MLBr_01828|M.leprae_Br4923          LLTAPLAVATAGAAGSFAGLSELAGLVGVAPPGLPSAPPVAAVAPVVPPS
MAB_0669|M.abscessus_ATCC_1997      ---------------------------------LPTSSVVPSGGSSVPVS
Mb3047c|M.bovis_AF2122/97           NIFG--------------------------------------AIPVLAGP
Rv3018c|M.tuberculosis_H37Rv        NLFG--------------------------------------VVPLLGGP
MMAR_2806|M.marinum_M               --------------------------------------------------
MUL_2932|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          AGS---PPAPGAPAAAAATFVPYVVAGRDPYEGFSPTVRD----------
Mvan_0415|M.vanbaalenii_PYR-1       TGT---APAPGAPAAATASFVPYAVAGRDPGTGFSPTVRD----------
MSMEG_0619|M.smegmatis_MC2_155      APA---GTTVAAPAPAAATFVPYAVANRDPGEGFTPTLGN----------
TH_3569|M.thermoresistible__bu      LPL---TXXX----------------------------------------
MAV_2429|M.avium_104                AGVSHVPTTASAPAPTMAGSAGGGPVGGGPGVGFGPTATDGIGAGMSDAL
MLBr_01828|M.leprae_Br4923          MPTLASIPTPTPMPAPAASTAPVVTPPGPPPVTAPPSVTG----------
MAB_0669|M.abscessus_ATCC_1997      TPT-APAHTVSSVPAPSAAISYAIPGLVPPGVSFGPKSTE----------
Mb3047c|M.bovis_AF2122/97           LLG----ALAAAVVPGVAGVTGLAGLAAVPAVGAAAGAPA----------
Rv3018c|M.tuberculosis_H37Rv        LLG----ALAAAVVPGVAGLAGVAGLAALPAVGAAAGAPA----------
MMAR_2806|M.marinum_M               -------RHVGDLQMMAARDNSDRTVVDAPHEILVSDSRG----------
MUL_2932|M.ulcerans_Agy99           -------RHVGDLQMMAARDNSDRAVVDAPHEILVSDSRG----------
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          --------------------STGAKAPAGTIPAAASGIAASAAERRKRRR
Mvan_0415|M.vanbaalenii_PYR-1       --------------------STSAKAPASGIPAAASGVAASAAERRKRRR
MSMEG_0619|M.smegmatis_MC2_155      --------------------KSQVAAPASGVPAAASGVAASLASRRKRRR
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MAV_2429|M.avium_104                YAVGLSGLSARGSASSRARRKSEEPAPDDLDAPAAAAAAAAGSKKARARR
MLBr_01828|M.leprae_Br4923          ------------------AGVESFGYLVGRLPSTARGVVGTSVRQQSSAP
MAB_0669|M.abscessus_ATCC_1997      ------------------KSSESAVDTVAAV-AAARGAVAAQARRRLRGK
Mb3047c|M.bovis_AF2122/97           -------------------------ALVGSVAPVSGGVVSPQARLVSAVE
Rv3018c|M.tuberculosis_H37Rv        -------------------------ALVGSVAPVSGGVVSPQARLVSAVE
MMAR_2806|M.marinum_M               ----------------------------GTAQSGASGSVRPGVGSASVVQ
MUL_2932|M.ulcerans_Agy99           ----------------------------GTAQSGASGSVRPGVGSASVVQ
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          RQKEEIKGRGYADAYA-------DYEELPDDGPPEQPAPRVTASTRGAGP
Mvan_0415|M.vanbaalenii_PYR-1       RQKDEIAGRAYADAYA-------DYEPEPDDEPPVRQEPRIAATERGAGP
MSMEG_0619|M.smegmatis_MC2_155      KKGAQIEERGYADAYM-------DYEE-PDEDPAPQPEPRVRASERGSDA
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MAV_2429|M.avium_104                RRRGTATDRAYRYEYM-------DLDTDSGPEDG-GPDDGPVASEASAGQ
MLBr_01828|M.leprae_Br4923          DRIEAPDAAATPQEQARSRWRRRAKVTPFDSSGSPNPKAAPTASDQGAGT
MAB_0669|M.abscessus_ATCC_1997      NKAEAGGRRHEYLEET-------AGMGATATADVP----AYAATGRGTGP
Mb3047c|M.bovis_AF2122/97           PAPASTSVS-------------------------------VLASDRGAGA
Rv3018c|M.tuberculosis_H37Rv        PAPASTSVS-------------------------------VLASDRGAGA
MMAR_2806|M.marinum_M               AASDGRPVS-------------------------------ELAGGRGAGT
MUL_2932|M.ulcerans_Agy99           AASPGRPVS-------------------------------ELAGGRGAGT
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          MGFAGTVSRGDEQ-AGGLTTLAGDSFGGGPREPMLPGTWDPDATDDRHTD
Mvan_0415|M.vanbaalenii_PYR-1       MGFAGTVSRDAAQ-AGGLTTLPGDPFGGGPKAPMLPGTWDPDTEPD----
MSMEG_0619|M.smegmatis_MC2_155      MGFTGTVTRHDVT-AAGLTTLTGDTFDDRPVTPMLPGTWDGDENPA----
TH_3569|M.thermoresistible__bu      --------------------------------------------------
MAV_2429|M.avium_104                LGFAGAATKSDAARPAGLATLTRDGSSEGPGVPMMPSTWDRD--------
MLBr_01828|M.leprae_Br4923          LGLAGTARQASSGPATGLVTLSNGTFSDSPRAPMLPRTWGADPTFCYNAA
MAB_0669|M.abscessus_ATCC_1997      LGFAGTAPAAASTHVAATVRLSSD--EARQVIPMLPSTWDAD--------
Mb3047c|M.bovis_AF2122/97           LGFVGTAGKESVGQPAGLTVLADEFGDGAP-VPMLPGSWGPDLVG-----
Rv3018c|M.tuberculosis_H37Rv        LGFVGTAGKESVGQPAGLTVLADEFGDGAP-VPMLPGSWGPDLVG-----
MMAR_2806|M.marinum_M               VGFAGVSATGTKVRPAGLSATGGGEFGSGAGVPVLPATWPLQVVGS----
MUL_2932|M.ulcerans_Agy99           VGFAGVSATGTKVRPAGLSATGGGEFGSGAGVPVLPATWPLQVVGS----
                                                                                      

Mflv_0325|M.gilvum_PYR-GCK          GRDGHDGHDGKEKP--
Mvan_0415|M.vanbaalenii_PYR-1       --ERHNHHDGKDSQ--
MSMEG_0619|M.smegmatis_MC2_155      --PSPDDPEGGPRR--
TH_3569|M.thermoresistible__bu      ----------------
MAV_2429|M.avium_104                ----------------
MLBr_01828|M.leprae_Br4923          DIGPAGGWDDE-----
MAB_0669|M.abscessus_ATCC_1997      ------GGDQN-----
Mb3047c|M.bovis_AF2122/97           -----VAGDGGLVSV-
Rv3018c|M.tuberculosis_H37Rv        -----VAGDGGLVSV-
MMAR_2806|M.marinum_M               -----TSGSGVSPPAL
MUL_2932|M.ulcerans_Agy99           -----TSGSGVSPPAL