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MKSIDELASDLSFTTAKTGADRSVTFLPDPPRARRRYTVISVDDHIVEPPDTFTGRLPQRFADRAPRVVE TDDGGQVWVYDGQVLPNVGFNAVVGRPVSEYGFEPVRFDEMRRGAWDIHERIKDMDLNGVYASLNFPSFL PGFAGQRLQQVTKDPELAWAAVRAWNDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIHENAERGFRAV SFSENPAMLGLPSIHSGHWDPMMAACAETGTVVNLHIGSSGSSPSTTDDAPADVPGVLFFAYAISAAVDW LYSGLPSRFPDLKICLSEGGIGWVAGLLDRLDHMLSYHEMYGTWRAMGESLTPAEVFTRNFWFCAVEDKS SFVQHHRIGTENIMVESDYPHCDSTWPHTQQTMHEQLDGLPADVIRKITWENAARLYQHPVPVAIAQNPE AF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2618 | - | - | 100% (422) | amidohydrolase |
| M. marinum M | MMAR_4742 | - | 4e-88 | 44.09% (372) | metal-dependent amidohydrolase |
| M. marinum M | MMAR_0273 | - | 7e-87 | 44.24% (373) | amidohydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2325c | - | 3e-05 | 26.38% (163) | antibiotic-resistance protein |
| M. gilvum PYR-GCK | Mflv_2441 | - | 3e-95 | 47.18% (373) | amidohydrolase 2 |
| M. tuberculosis H37Rv | Rv2303c | - | 3e-05 | 26.38% (163) | antibiotic-resistance protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | MAV_2993 | - | 0.0 | 84.83% (422) | amidohydrolase 2 |
| M. smegmatis MC2 155 | MSMEG_4837 | - | 2e-88 | 45.45% (374) | amidohydrolase 2 |
| M. thermoresistible (build 8) | TH_2339 | - | 3e-72 | 40.05% (372) | amidohydrolase 2 |
| M. ulcerans Agy99 | MUL_3143 | - | 0.0 | 98.99% (396) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_4211 | - | 3e-94 | 46.65% (373) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2618|M.marinum_M MKSIDELASDLSFTTAKTGADRSVTFLPDPPRARRRYTVISVDDHIVEPP
MUL_3143|M.ulcerans_Agy99 --------------------------MTDPPRARRRYTVISVDDHIVEPP
MAV_2993|M.avium_104 MKSIDELATDLNFTTAKTGAQRTVTLLPDPPRAPRRYTLISVDDHIVEPP
Mflv_2441|M.gilvum_PYR-GCK -------------------------------MDKNDMILISVDDHIVEPP
Mvan_4211|M.vanbaalenii_PYR-1 ---------------MSRAPARKGGNGRSAVMNRDDMILISVDDHIVEPP
MSMEG_4837|M.smegmatis_MC2_155 -------------------------------MNKDDMILISVDDHIIEPP
TH_2339|M.thermoresistible__bu ---------------------------MSHDLRPEDLILVSIDDHVVEPP
Mb2325c|M.bovis_AF2122/97 ---------------------------------------MTAPEPRVPVI
Rv2303c|M.tuberculosis_H37Rv ---------------------------------------MTAPEPRVPVI
:: : :
MMAR_2618|M.marinum_M DTFTGRLPQRFADRAPRVVETDDGGQVWVYDGQVLPNVGFNAVVGRPVSE
MUL_3143|M.ulcerans_Agy99 DTFTGRLPQRFADRAPRVVETDDGGQVWVYDGQVLPNVGFNAVVGRPVSE
MAV_2993|M.avium_104 DTFAGRVPRKFADRAPCVVDTDTGGQTWVYDGRQLPNVGFNAVVGRPVAE
Mflv_2441|M.gilvum_PYR-GCK DMFKNHLSKKYLDEAPRLVHNEDGSDTWQFRDVVIPNVALNAVAGRPKEE
Mvan_4211|M.vanbaalenii_PYR-1 DMFKNHLPRKYLDEAPRLVHNPDGSDTWQFRDVVIPNVALNAVAGRPKEE
MSMEG_4837|M.smegmatis_MC2_155 DMFKNHLPAKYRDEAPRLVHNPDGSDTWQFRDTVIPNVALNAVAGRPKEE
TH_2339|M.thermoresistible__bu DMFLRHVPAKYRDEAPIVVTDENGVDQWMYQGRPQGVSGLNAVVSWPPEE
Mb2325c|M.bovis_AF2122/97 DMWAPFVPS-----AEVIDDLREG-----FPVELLSYFEVFTKTTISAEQ
Rv2303c|M.tuberculosis_H37Rv DMWAPFVPS-----AEVIDDLREG-----FPVELLSYFEVFTKTTISAEQ
* : :. * : * : . : . . :
MMAR_2618|M.marinum_M YGFEPVRFDEMRRGAWDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQ
MUL_3143|M.ulcerans_Agy99 YGFEPVRFDEMRRGAWDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQ
MAV_2993|M.avium_104 YGFEPVRFDEMRRGAWDIHERVKDMDLNGVYASLNFPSFLPGFAGQRLQQ
Mflv_2441|M.gilvum_PYR-GCK YGLEPQGLDEIRPGCWQVDERVKDMNAGGILGSMCFPSFP-GFAGR--LF
Mvan_4211|M.vanbaalenii_PYR-1 YGLEPQGLDEIRPGCWQVDERVKDMNAGGILGSMCFPSFP-GFAGR--LF
MSMEG_4837|M.smegmatis_MC2_155 YGLEPQGLDEIRKGCYDPNERVKDMNAGGVLATMNFPSFP-GFAAR--LF
TH_2339|M.thermoresistible__bu WGRNPARFAEMRPGVYDVHERVRDMNRNGILASMCFPTFT-GFSAR--HL
Mb2325c|M.bovis_AF2122/97 FG---AYAESLRR---TDDQILDSLDDAGITRSLIT-----GFDER----
Rv2303c|M.tuberculosis_H37Rv FG---AYAESLRR---TDDQILDSLDDAGITRSLIT-----GFDER----
:* .:* .: : .:: *: :: ** :
MMAR_2618|M.marinum_M VTKDPELAWAAVRAWNDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIH
MUL_3143|M.ulcerans_Agy99 VTKDPELAWAAVRAWNDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIH
MAV_2993|M.avium_104 LTDDRDLALACVRAWNDWHFEVWAGSYPDRIIPCQLPWLLDPELGAKMIY
Mflv_2441|M.gilvum_PYR-GCK ATEDPEFSLALVQAYNDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIR
Mvan_4211|M.vanbaalenii_PYR-1 ATEDAEFSLALVQAYNDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIR
MSMEG_4837|M.smegmatis_MC2_155 ATDDEEFSLALVQAYNDWHIDEWCASNPGRFIPMAIPAIWNPGLAAAEVR
TH_2339|M.thermoresistible__bu NMHREHVTLIMVSAYNDWHIDEWAGSYPGRFIPIAILPTWNPEAMCAEIR
Mb2325c|M.bovis_AF2122/97 -------STCGVTFVHNASVAAVAARYPDRFLPFAGADILAGDSAVDEFE
Rv2303c|M.tuberculosis_H37Rv -------STCGVTFVHNASVAAVAARYPDRFLPFAGADILAGDSAVDEFE
: * :: . .. * *::* .
MMAR_2618|M.marinum_M -ENAERGFRAVSFSENPAMLGLPSIHS-GHWDPMMAACAETGTVVNLHIG
MUL_3143|M.ulcerans_Agy99 -ENAERGFRAVSFSENPAMLGLPSIHS-GHWDPMMAACAETGTVVNLHIG
MAV_2993|M.avium_104 -ENAERGFHAVTFSENPAMLGLPSIHT-GHWDPMMAACAETGTVVNLHIG
Mflv_2441|M.gilvum_PYR-GCK -RNAARGVHSLTFSENPSAMGYPSFHDFDHWKPMWDALVDTDTVLNVHIG
Mvan_4211|M.vanbaalenii_PYR-1 -RNAARGVHSLTFSENPSAMGYPSFHDFEHWKPMWDALVDTDTVLNVHIG
MSMEG_4837|M.smegmatis_MC2_155 -RVAEKGVHSLTFTENPSTLGYPSFHDLEYWRPLWQALVDTETVMNVHIG
TH_2339|M.thermoresistible__bu -RVAAKGCRAVTMPELPHLEGLPSYHDEDYWGPVFRTLSEENVVMCLHIG
Mb2325c|M.bovis_AF2122/97 RWVVEHGFRGLSLR--PFMIGRPASDP--AYFPCYAKCVELGVPVSIHTS
Rv2303c|M.tuberculosis_H37Rv RWVVEHGFRGLSLR--PFMIGRPASDP--AYFPCYAKCVELGVPVSIHTS
. :* :.::: * * *: . : * : . : :* .
MMAR_2618|M.marinum_M SSGSSPSTTDDAPADVPGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSE
MUL_3143|M.ulcerans_Agy99 SSGSSPSTTDDAPADVPGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSE
MAV_2993|M.avium_104 SSGSSPSTTADAPPDVQGVLFFAYAISAAVDWLYSGLPSRFPNLKICLSE
Mflv_2441|M.gilvum_PYR-GCK SSGRLAITAPDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSE
Mvan_4211|M.vanbaalenii_PYR-1 SSGRLAITAPDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSE
MSMEG_4837|M.smegmatis_MC2_155 SSGKLAITAPDAPMDVMITLQPMNIVQAAADLLWSAPIKEFPTLKIALSE
TH_2339|M.thermoresistible__bu TGFGAISMAPDAPIDNMIILATQVSAMCAQDLLWGPAMRNYPDLKFAFSE
Mb2325c|M.bovis_AF2122/97 ADWTRTRLSDLG-----------------HPRHIDDVACRFPELTILMSH
Rv2303c|M.tuberculosis_H37Rv ADWTRTRLSDLG-----------------HPRHIDDVACRFPELTILMSH
:. : . . .:* *.: :*.
MMAR_2618|M.marinum_M GGIGWVAGLLDRLDHMLSYHEMYGTWRAMGESLTPAEVFTRNFWFCAVED
MUL_3143|M.ulcerans_Agy99 GRIGWVAGLLDRLDHMLSYHEMYGTWRAMGESLTSAEVFTRNFWFCAVED
MAV_2993|M.avium_104 GGIGWVAGLLDRLDHMLSYHAMYGTWQALGERLTPAEVLVRNFWFCAVED
Mflv_2441|M.gilvum_PYR-GCK GGTGWIPYFLERVDRTYEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIAD
Mvan_4211|M.vanbaalenii_PYR-1 GGTGWIPYFLERVDRTYEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIAD
MSMEG_4837|M.smegmatis_MC2_155 GGTGWIPYFLDRVDRTFEMHSTWTH-QNFGGKLP-SEVFREHFMTCFISD
TH_2339|M.thermoresistible__bu GGIGWIPFYLDRCDRHYTN-QKWLR-RDFGDKLP-SDVFREHSLACYVTD
Mb2325c|M.bovis_AF2122/97 GGYPWV---LQACLIAWKHPNVYLE-------------LAAHRPKYFASP
Rv2303c|M.tuberculosis_H37Rv GGYPWV---LQACLIAWKHPNVYLE-------------LAAHRPKYFASP
* *: *: : : :
MMAR_2618|M.marinum_M KSSFVQHHRIGTENIMVESDYPHCDSTWPHTQQTMHEQLDG--LPADVIR
MUL_3143|M.ulcerans_Agy99 KSSFVQHYRIGTENIMVESDYPHCDSTWPHTQQTMHEQLDG--LPADVIR
MAV_2993|M.avium_104 KSSFVQRDRIGVDNIMLEADYPHCDSTWPHTQQTVHEQIGG--LPADVIR
Mflv_2441|M.gilvum_PYR-GCK PVGVATRHQIGVDNICWEADYPHSDSMWPGAPEQLDEVLKANNVPDDEIN
Mvan_4211|M.vanbaalenii_PYR-1 PVGVATRHQIGVDNICWEADYPHSDSMWPGAPEQLDEVLKVNSVPDDEID
MSMEG_4837|M.smegmatis_MC2_155 PVGVKNRHMIGIDNICWEMDYPHSDSMWPGAPEELSAVFDTYDVPDDEIN
TH_2339|M.thermoresistible__bu KTSLKLRHEIGIDIIAWECDYPHSDCFWPDAPEQVHAELRAAGADDFDIN
Mb2325c|M.bovis_AF2122/97 GAGWEPLMRFGQTTIRNKIVYGTGGFLINRPYLQLCDEMRALPVPREVLE
Rv2303c|M.tuberculosis_H37Rv GAGWEPLMRFGQTTIRNKIVYGTGGFLINRPYLQLCDEMRALPVPREVLE
. :* * : * . . : : :
MMAR_2618|M.marinum_M KITWENAARLYQHPVPVAIAQNPEAF------------------------
MUL_3143|M.ulcerans_Agy99 KITWENAARLYQHPVPVAIAQNPEAF------------------------
MAV_2993|M.avium_104 KFTWQNASRLYQHPVPIQVQQNPDAF------------------------
Mflv_2441|M.gilvum_PYR-GCK KMTYENAMRWYHWDPFTHIAKEQATVGALRKAAEGHDVSIQALSNKEKTG
Mvan_4211|M.vanbaalenii_PYR-1 KMTYQNAMRWYHWDPFTHIPKEQATVGALRKAAEGHDVSIQALSHKEKTG
MSMEG_4837|M.smegmatis_MC2_155 KITHENAMRLYHFDPFAHVPKEQATVGALRKAAEGHDVSIRALSKKDKTG
TH_2339|M.thermoresistible__bu KITWENSCRFFSWDPFEHTPRAEATVGALRAKATDVDTTIRSR-------
Mb2325c|M.bovis_AF2122/97 DWLWRNATRVLRLDT-----------------------------------
Rv2303c|M.tuberculosis_H37Rv DWLWRNATRVLRLDT-----------------------------------
. .*: *
MMAR_2618|M.marinum_M ------------------
MUL_3143|M.ulcerans_Agy99 ------------------
MAV_2993|M.avium_104 ------------------
Mflv_2441|M.gilvum_PYR-GCK TTFSDFAASAKSISGNKD
Mvan_4211|M.vanbaalenii_PYR-1 ATFADFAARAKEITGNTD
MSMEG_4837|M.smegmatis_MC2_155 ASFADFQANAKAVSGARD
TH_2339|M.thermoresistible__bu AEWAQLYEQKQQFAQA--
Mb2325c|M.bovis_AF2122/97 ------------------
Rv2303c|M.tuberculosis_H37Rv ------------------