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TAPEPRVPVIDMWAPFVPSAEVIDDLREGFPVELLSYFEVFTKTTISAEQFGAYAESLRRTDDQILDSLD DAGITRSLITGFDERSTCGVTFVHNASVAAVAARYPDRFLPFAGADILAGDSAVDEFERWVVEHGFRGLS LRPFMIGRPASDPAYFPCYAKCVELGVPVSIHTSADWTRTRLSDLGHPRHIDDVACRFPELTILMSHGGY PWVLQACLIAWKHPNVYLELAAHRPKYFASPGAGWEPLMRFGQTTIRNKIVYGTGGFLINRPYLQLCDEM RALPVPREVLEDWLWRNATRVLRLDT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2303c | - | - | 100% (307) | PROBABLE ANTIBIOTIC-RESISTANCE PROTEIN |
| M. tuberculosis H37Rv | Rv3510c | - | 2e-27 | 36.05% (258) | hypothetical protein Rv3510c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2325c | - | 0.0 | 100.00% (307) | antibiotic-resistance protein |
| M. gilvum PYR-GCK | Mflv_4348 | - | 1e-17 | 26.89% (238) | amidohydrolase 2 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0299 | - | 1e-06 | 22.75% (189) | putative amidohydrolase (aminocarboxymuconate-semialdehyde |
| M. marinum M | MMAR_4998 | - | 8e-23 | 34.98% (243) | hypothetical protein MMAR_4998 |
| M. avium 104 | MAV_0646 | - | 3e-26 | 33.88% (245) | amidohydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_2232 | - | 3e-16 | 27.98% (243) | amidohydrolase family protein |
| M. thermoresistible (build 8) | TH_4033 | - | 1e-20 | 31.75% (252) | PUTATIVE amidohydrolase 2 |
| M. ulcerans Agy99 | MUL_3876 | - | 2e-19 | 29.71% (239) | metal-dependent hydrolase |
| M. vanbaalenii PYR-1 | Mvan_4952 | - | 1e-21 | 34.10% (217) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4348|M.gilvum_PYR-GCK ----MSD----RVIDCLVNVHFG---ETANQPEFMLKVRDDYFKGPQSLY
MSMEG_2232|M.smegmatis_MC2_155 ----MTESPAGRAIDCLANVHFG---ETQNQPAFMTKVRDDYFKGPKSMY
MUL_3876|M.ulcerans_Agy99 ----MTD----RAIDCLVNVHFG---EAEAQPNWMLKVRDDYFKGPDSMF
Rv2303c|M.tuberculosis_H37Rv ---MTAPEPRVPVIDMWAPFVPSAEVIDDLREGFPVELLSYFEVFTKTTI
Mb2325c|M.bovis_AF2122/97 ---MTAPEPRVPVIDMWAPFVPSAEVIDDLREGFPVELLSYFEVFTKTTI
MMAR_4998|M.marinum_M -----------MTIDAWMQHP----TQRFLRS----DMLASLRRWTDSSI
MAV_0646|M.avium_104 -----------MTIDVWMQHP----TVRFLRS----DMLASLRRWTGGSI
TH_4033|M.thermoresistible__bu VYEYGVDFDAVTAIDMHAHIEIDCHGHQAYDDELVAATTAYFKMDAGPP-
Mvan_4952|M.vanbaalenii_PYR-1 MYEYGIDFDAVAAIDIHTHVEVDSHGHRAYDDVLVEATGKYFKMPQGSKG
MAB_0299|M.abscessus_ATCC_1997 ----------MTSVRIDIHAHLWSDEYLSLLDGYG-RPATDVHRGLGAGA
:
Mflv_4348|M.gilvum_PYR-GCK DQVELPALLD-----------EMAEHGVEKAILMDNL-------------
MSMEG_2232|M.smegmatis_MC2_155 DPIDLGALLE-----------EMDANGVERAILMDNL-------------
MUL_3876|M.ulcerans_Agy99 APVDLAQLLD-----------EMDEQGVQRAILMDSL-------------
Rv2303c|M.tuberculosis_H37Rv SAEQFGAYAESLRRTDDQILDSLDDAGITRSLITGFDER-------STCG
Mb2325c|M.bovis_AF2122/97 SAEQFGAYAESLRRTDDQILDSLDDAGITRSLITGFDER-------STCG
MMAR_4998|M.marinum_M PEAQIPIEAT---------IASMDAADVEFGLLSAWR---------GPNG
MAV_0646|M.avium_104 PDTDIPIEAT---------LASMDAAGVGYGLLSAWR---------GPNG
TH_4033|M.thermoresistible__bu --ADVDAVADY--------YRRANIAAVVFTIDAQSG-----------MG
Mvan_4952|M.vanbaalenii_PYR-1 VVAGVDAVAEQ--------YRQHNTAAVVFTIDARHG-----------MR
MAB_0299|M.abscessus_ATCC_1997 TRDDLDGRFEL-----------MDEAGVDLQILTATPASPHFEDQAAAVA
. : :
Mflv_4348|M.gilvum_PYR-GCK -VKPSVTARKFAEERPDKFALAIGGVNLLRPMPSLRELSSVVADLPVAYA
MSMEG_2232|M.smegmatis_MC2_155 -TKPSVTARKFVEAHPERFALAMGGVNLLRPIPSLRELAAAVRDLPVAYA
MUL_3876|M.ulcerans_Agy99 -ASPSLTACKFVQAKPDRFALAMGGINLLRPVRPLRELTAIVGELPVAYA
Rv2303c|M.tuberculosis_H37Rv VTFVHNASVAAVAARYPDRFLPFAGADILAGDSAVDEFERWVVEHGFRGL
Mb2325c|M.bovis_AF2122/97 VTFVHNASVAAVAARYPDRFLPFAGADILAGDSAVDEFERWVVEHGFRGL
MMAR_4998|M.marinum_M QDLVSNDEVAGWVDLHPQRFAGLAAVDLDRPMVAVRELRSRIASG-FVGL
MAV_0646|M.avium_104 QDLVSNDEVAQWVAAHPNRFAGLAAVDLDRPMEAVRELRCRIADGGFVGL
TH_4033|M.thermoresistible__bu HPPNSIEDLVAGAARNNDVLIPFGSVDPWQGRHAVRRVREQVRDHGVKGF
Mvan_4952|M.vanbaalenii_PYR-1 HAPNSIEDLVAGAARNNDVLIPFGSVDPWQGRHAVHRVHELVRDHGVKGF
MAB_0299|M.abscessus_ATCC_1997 SARFINDEYAKLSSEYPGRFGALASLPLPHVPAALEELARAIDELGMYGA
:.. .: .. : . .
Mflv_4348|M.gilvum_PYR-GCK AVGPSFWGDGMYPPSDAVYYPLYTKCAELGLPLCINTGLPGPPIPGEVQN
MSMEG_2232|M.smegmatis_MC2_155 VVGPSFWGDGQYPPSDAVYYPLYTKCAELDLPLCVNTGLPGPPIPGEVQN
MUL_3876|M.ulcerans_Agy99 AVGPSFWGEGQYPPSDAVYYPLYVKCAELELALCINTGIPGPPIPGEVQH
Rv2303c|M.tuberculosis_H37Rv SLRPFMIG---RPASDPAYFPCYAKCVELGVPVSIHTSADWTRTRLSDLG
Mb2325c|M.bovis_AF2122/97 SLRPFMIG---RPASDPAYFPCYAKCVELGVPVSIHTSADWTRTRLSDLG
MMAR_4998|M.marinum_M RVVPWLWE---APPTDRRYYPLFAECVESGVPFCTQVGHTGP-LRPSETG
MAV_0646|M.avium_104 RVVPWLWN---APPTDRRYYPLFAACVEAGVPFCTQVGHTGP-LRPSETG
TH_4033|M.thermoresistible__bu KFHPSFQA---FEPNDRVFYPIYEAIAEAGVPALFHTGQTGLGSGLPGGH
Mvan_4952|M.vanbaalenii_PYR-1 KFHPSMQA---FEPNDRAYYPIYHAIAEAGVPALFHTGQTGMGAGLPGGH
MAB_0299|M.abscessus_ATCC_1997 SITTSVLG---RSIADPIFDPLYAELNRRRAVLFVHPAGCGAESSLITDH
. . . * : * : . : .
Mflv_4348|M.gilvum_PYR-GCK -----------------PIHLDRVCVRFPELKLCMIHGADPWWDVAIRLL
MSMEG_2232|M.smegmatis_MC2_155 -----------------PIHLDRVCVRFPELRLCMIHGADPWWDIAIRML
MUL_3876|M.ulcerans_Agy99 -----------------PMHLDRVCVRFPELRLCMIHGADPWWDVAIRLL
Rv2303c|M.tuberculosis_H37Rv ---------------HPR-HIDDVACRFPELTILMSHGGYPWVLQACLIA
Mb2325c|M.bovis_AF2122/97 ---------------HPR-HIDDVACRFPELTILMSHGGYPWVLQACLIA
MMAR_4998|M.marinum_M ---------------RPIPYIDQVALDFPELVIVCGHVGYPWTEEMVAVA
MAV_0646|M.avium_104 ---------------RPIPYIDQVALDFPELVIVCGHVGYPWTEEMVAVA
TH_4033|M.thermoresistible__bu GIKLRY---------SDPMLLDDVAADFPELTIVMAHPAVPWVDAQIAVA
Mvan_4952|M.vanbaalenii_PYR-1 GIKLRY---------SDPMLLDDVAADFPELTIVMAHPAVPWVDAQISIA
MAB_0299|M.abscessus_ATCC_1997 SLTWSIGAPIEDTVAIMHLIVAGVPSRYPDMKIVTCHLGGALPMVLERAH
: * :*:: : * . .
Mflv_4348|M.gilvum_PYR-GCK IKYANLRIMTSAWSPKRLP------------DSLLHYMRT-RGKNKVIFA
MSMEG_2232|M.smegmatis_MC2_155 IKYKNLRLMTSAWSPKRLP------------ESLLHYMRT-RGPDKIIFA
MUL_3876|M.ulcerans_Agy99 LKYSNSRLMTSAWTPKRLP------------ESLLHYMRT-RGKNKVIFA
Rv2303c|M.tuberculosis_H37Rv WKHPNVYLELAAHRPKYFAS------PGAGWEPLMRFGQT-TIRNKIVYG
Mb2325c|M.bovis_AF2122/97 WKHPNVYLELAAHRPKYFAS------PGAGWEPLMRFGQT-TIRNKIVYG
MMAR_4998|M.marinum_M RKHENVYIDTSAYTIKRLP------------HELIRFMKTGTGRRKVMFG
MAV_0646|M.avium_104 RKHENVYIDTSAYTIERLP------------DELVRFIKTGTGQRKVLFG
TH_4033|M.thermoresistible__bu AHKANVYVDLSGWSPKYFP------------PQLVRAIGR-QLRTKVLFG
Mvan_4952|M.vanbaalenii_PYR-1 THKANVYIDLSGWSPKYFP------------AQLVHAMGR-QLRTKVLFG
MAB_0299|M.abscessus_ATCC_1997 RQVTEWEATQCPEAPRDAARRLWYDTVGHDHTPALRAAVASLGVDRLIFG
: : . . . :: ::::.
Mflv_4348|M.gilvum_PYR-GCK SDWPVLRQSRVVPE--ALALDLPPDVLDNYLYNNANDFFFG-TDEQEI
MSMEG_2232|M.smegmatis_MC2_155 SDFPVLRMNRVVPE--ARALDLPPDVLDNYLYHNAAEFFFGGRQPQEF
MUL_3876|M.ulcerans_Agy99 SDWPVLRMRRVVPE--ARALDLPADVLANYLYNNAQEFFFGEESGR--
Rv2303c|M.tuberculosis_H37Rv TGGFLINRPYLQLCDEMRALPVPREVLEDWLWRNATRVLRLDT-----
Mb2325c|M.bovis_AF2122/97 TGGFLINRPYLQLCDEMRALPVPREVLEDWLWRNATRVLRLDT-----
MMAR_4998|M.marinum_M TNFPMIAHAHALAG--LDELGLEDEARRDFLHGNAERVFGLAQRPPR-
MAV_0646|M.avium_104 TNYPMITAEHALAG--LDGLGLSDEARRDFLHGNAERVFRLEAAT---
TH_4033|M.thermoresistible__bu TDFPYIKLDRWRRD--FDTLDIDPAVLPLVYKENALRVLGIGSGA---
Mvan_4952|M.vanbaalenii_PYR-1 TDFPYIQIDRWRRD--FDTLDIDPAVVPLIYKQNALRVLGVASHRP--
MAB_0299|M.abscessus_ATCC_1997 SDFPYQAGPRYVSSATYIEEGLSAEDASAILDHNGAELLGLTGV----
:. : *. .: