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M. avium 104 MAV_2993 (-)

annotation: amidohydrolase 2
coordinates: 3029718 - 3030986
length: 422

KSIDELATDLNFTTAKTGAQRTVTLLPDPPRAPRRYTLISVDDHIVEPPDTFAGRVPRKFADRAPCVVDT
DTGGQTWVYDGRQLPNVGFNAVVGRPVAEYGFEPVRFDEMRRGAWDIHERVKDMDLNGVYASLNFPSFLP
GFAGQRLQQLTDDRDLALACVRAWNDWHFEVWAGSYPDRIIPCQLPWLLDPELGAKMIYENAERGFHAVT
FSENPAMLGLPSIHTGHWDPMMAACAETGTVVNLHIGSSGSSPSTTADAPPDVQGVLFFAYAISAAVDWL
YSGLPSRFPNLKICLSEGGIGWVAGLLDRLDHMLSYHAMYGTWQALGERLTPAEVLVRNFWFCAVEDKSS
FVQRDRIGVDNIMLEADYPHCDSTWPHTQQTVHEQIGGLPADVIRKFTWQNASRLYQHPVPIQVQQNPDA
F*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_2993--100% (422)amidohydrolase 2
M. avium 104MAV_0907-1e-9045.82% (371) amidohydrolase 2
M. avium 104MAV_1837-1e-8041.11% (377) amidohydrolase 2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2441-5e-9247.58% (372) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_2618-0.084.83% (422) amidohydrolase
M. smegmatis MC2 155MSMEG_4837-2e-8845.97% (372) amidohydrolase 2
M. thermoresistible (build 8)TH_2339-4e-7340.37% (379) amidohydrolase 2
M. ulcerans Agy99MUL_3143-0.084.34% (396) amidohydrolase
M. vanbaalenii PYR-1Mvan_4211-2e-9348.39% (372) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2441|M.gilvum_PYR-GCK          -------------------------------MDKNDMILISVDDHIVEPP
Mvan_4211|M.vanbaalenii_PYR-1       ---------------MSRAPARKGGNGRSAVMNRDDMILISVDDHIVEPP
MSMEG_4837|M.smegmatis_MC2_155      -------------------------------MNKDDMILISVDDHIIEPP
TH_2339|M.thermoresistible__bu      ---------------------------MSHDLRPEDLILVSIDDHVVEPP
MMAR_2618|M.marinum_M               MKSIDELASDLSFTTAKTGADRSVTFLPDPPRARRRYTVISVDDHIVEPP
MUL_3143|M.ulcerans_Agy99           --------------------------MTDPPRARRRYTVISVDDHIVEPP
MAV_2993|M.avium_104                MKSIDELATDLNFTTAKTGAQRTVTLLPDPPRAPRRYTLISVDDHIVEPP
                                                                          ::*:***::***

Mflv_2441|M.gilvum_PYR-GCK          DMFKNHLSKKYLDEAPRLVHNEDGSDTWQFRDVVIPNVALNAVAGRPKEE
Mvan_4211|M.vanbaalenii_PYR-1       DMFKNHLPRKYLDEAPRLVHNPDGSDTWQFRDVVIPNVALNAVAGRPKEE
MSMEG_4837|M.smegmatis_MC2_155      DMFKNHLPAKYRDEAPRLVHNPDGSDTWQFRDTVIPNVALNAVAGRPKEE
TH_2339|M.thermoresistible__bu      DMFLRHVPAKYRDEAPIVVTDENGVDQWMYQGRPQGVSGLNAVVSWPPEE
MMAR_2618|M.marinum_M               DTFTGRLPQRFADRAPRVVETDDGGQVWVYDGQVLPNVGFNAVVGRPVSE
MUL_3143|M.ulcerans_Agy99           DTFTGRLPQRFADRAPRVVETDDGGQVWVYDGQVLPNVGFNAVVGRPVSE
MAV_2993|M.avium_104                DTFAGRVPRKFADRAPCVVDTDTGGQTWVYDGRQLPNVGFNAVVGRPVAE
                                    * *  ::. :: *.** :*    * : * : .      .:***.. *  *

Mflv_2441|M.gilvum_PYR-GCK          YGLEPQGLDEIRPGCWQVDERVKDMNAGGILGSMCFPSFP-GFAGRLFA-
Mvan_4211|M.vanbaalenii_PYR-1       YGLEPQGLDEIRPGCWQVDERVKDMNAGGILGSMCFPSFP-GFAGRLFA-
MSMEG_4837|M.smegmatis_MC2_155      YGLEPQGLDEIRKGCYDPNERVKDMNAGGVLATMNFPSFP-GFAARLFA-
TH_2339|M.thermoresistible__bu      WGRNPARFAEMRPGVYDVHERVRDMNRNGILASMCFPTFT-GFSARHLN-
MMAR_2618|M.marinum_M               YGFEPVRFDEMRRGAWDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQ
MUL_3143|M.ulcerans_Agy99           YGFEPVRFDEMRRGAWDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQ
MAV_2993|M.avium_104                YGFEPVRFDEMRRGAWDIHERVKDMDLNGVYASLNFPSFLPGFAGQRLQQ
                                    :* :*  : *:* * :: .**::**: .*: .:: **:*  **:.: :  

Mflv_2441|M.gilvum_PYR-GCK          -TEDPEFSLALVQAYNDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIR
Mvan_4211|M.vanbaalenii_PYR-1       -TEDAEFSLALVQAYNDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIR
MSMEG_4837|M.smegmatis_MC2_155      -TDDEEFSLALVQAYNDWHIDEWCASNPGRFIPMAIPAIWNPGLAAAEVR
TH_2339|M.thermoresistible__bu      -MHREHVTLIMVSAYNDWHIDEWAGSYPGRFIPIAILPTWNPEAMCAEIR
MMAR_2618|M.marinum_M               VTKDPELAWAAVRAWNDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIH
MUL_3143|M.ulcerans_Agy99           VTKDPELAWAAVRAWNDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIH
MAV_2993|M.avium_104                LTDDRDLALACVRAWNDWHFEVWAGSYPDRIIPCQLPWLLDPELGAKMIY
                                      .  ..:   * *:****.: *... * *:**  :    :*   .  : 

Mflv_2441|M.gilvum_PYR-GCK          RNAARGVHSLTFSENPSAMGYPSFHDFDHWKPMWDALVDTDTVLNVHIGS
Mvan_4211|M.vanbaalenii_PYR-1       RNAARGVHSLTFSENPSAMGYPSFHDFEHWKPMWDALVDTDTVLNVHIGS
MSMEG_4837|M.smegmatis_MC2_155      RVAEKGVHSLTFTENPSTLGYPSFHDLEYWRPLWQALVDTETVMNVHIGS
TH_2339|M.thermoresistible__bu      RVAAKGCRAVTMPELPHLEGLPSYHDEDYWGPVFRTLSEENVVMCLHIGT
MMAR_2618|M.marinum_M               ENAERGFRAVSFSENPAMLGLPSIHSG-HWDPMMAACAETGTVVNLHIGS
MUL_3143|M.ulcerans_Agy99           ENAERGFRAVSFSENPAMLGLPSIHSG-HWDPMMAACAETGTVVNLHIGS
MAV_2993|M.avium_104                ENAERGFHAVTFSENPAMLGLPSIHTG-HWDPMMAACAETGTVVNLHIGS
                                    . * :* :::::.* *   * ** *   :* *:  :  :  .*: :***:

Mflv_2441|M.gilvum_PYR-GCK          SGRLAITAPDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEG
Mvan_4211|M.vanbaalenii_PYR-1       SGRLAITAPDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEG
MSMEG_4837|M.smegmatis_MC2_155      SGKLAITAPDAPMDVMITLQPMNIVQAAADLLWSAPIKEFPTLKIALSEG
TH_2339|M.thermoresistible__bu      GFGAISMAPDAPIDNMIILATQVSAMCAQDLLWGPAMRNYPDLKFAFSEG
MMAR_2618|M.marinum_M               SGSSPSTTDDAPADVPGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSEG
MUL_3143|M.ulcerans_Agy99           SGSSPSTTDDAPADVPGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSEG
MAV_2993|M.avium_104                SGSSPSTTADAPPDVQGVLFFAYAISAAVDWLYSGLPSRFPNLKICLSEG
                                    .      : *** *    *       .* * *:.    .:* **:.:***

Mflv_2441|M.gilvum_PYR-GCK          GTGWIPYFLERVDRTYEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIADP
Mvan_4211|M.vanbaalenii_PYR-1       GTGWIPYFLERVDRTYEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIADP
MSMEG_4837|M.smegmatis_MC2_155      GTGWIPYFLDRVDRTFEMHSTWTH-QNFGGKLP-SEVFREHFMTCFISDP
TH_2339|M.thermoresistible__bu      GIGWIPFYLDRCDRHYTN-QKWLR-RDFGDKLP-SDVFREHSLACYVTDK
MMAR_2618|M.marinum_M               GIGWVAGLLDRLDHMLSYHEMYGTWRAMGESLTPAEVFTRNFWFCAVEDK
MUL_3143|M.ulcerans_Agy99           RIGWVAGLLDRLDHMLSYHEMYGTWRAMGESLTSAEVFTRNFWFCAVEDK
MAV_2993|M.avium_104                GIGWVAGLLDRLDHMLSYHAMYGTWQALGERLTPAEVLVRNFWFCAVEDK
                                      **:.  *:* *:       :   : :   *. ::*: .:   * : * 

Mflv_2441|M.gilvum_PYR-GCK          VGVATRHQIGVDNICWEADYPHSDSMWPGAPEQLDEVLKANNVPDDEINK
Mvan_4211|M.vanbaalenii_PYR-1       VGVATRHQIGVDNICWEADYPHSDSMWPGAPEQLDEVLKVNSVPDDEIDK
MSMEG_4837|M.smegmatis_MC2_155      VGVKNRHMIGIDNICWEMDYPHSDSMWPGAPEELSAVFDTYDVPDDEINK
TH_2339|M.thermoresistible__bu      TSLKLRHEIGIDIIAWECDYPHSDCFWPDAPEQVHAELRAAGADDFDINK
MMAR_2618|M.marinum_M               SSFVQHHRIGTENIMVESDYPHCDSTWPHTQQTMHEQLDG--LPADVIRK
MUL_3143|M.ulcerans_Agy99           SSFVQHYRIGTENIMVESDYPHCDSTWPHTQQTMHEQLDG--LPADVIRK
MAV_2993|M.avium_104                SSFVQRDRIGVDNIMLEADYPHCDSTWPHTQQTVHEQIGG--LPADVIRK
                                     ..  :  ** : *  * ****.*. ** : : :   :         * *

Mflv_2441|M.gilvum_PYR-GCK          MTYENAMRWYHWDPFTHIAKEQATVGALRKAAEGHDVSIQALSNKEKTGT
Mvan_4211|M.vanbaalenii_PYR-1       MTYQNAMRWYHWDPFTHIPKEQATVGALRKAAEGHDVSIQALSHKEKTGA
MSMEG_4837|M.smegmatis_MC2_155      ITHENAMRLYHFDPFAHVPKEQATVGALRKAAEGHDVSIRALSKKDKTGA
TH_2339|M.thermoresistible__bu      ITWENSCRFFSWDPFEHTPRAEATVGALRAKATDVDTTIRSR-------A
MMAR_2618|M.marinum_M               ITWENAARLYQHPVPVAIAQNPEAF-------------------------
MUL_3143|M.ulcerans_Agy99           ITWENAARLYQHPVPVAIAQNPEAF-------------------------
MAV_2993|M.avium_104                FTWQNASRLYQHPVPIQVQQNPDAF-------------------------
                                    :* :*: * :         :   :.                         

Mflv_2441|M.gilvum_PYR-GCK          TFSDFAASAKSISGNKD
Mvan_4211|M.vanbaalenii_PYR-1       TFADFAARAKEITGNTD
MSMEG_4837|M.smegmatis_MC2_155      SFADFQANAKAVSGARD
TH_2339|M.thermoresistible__bu      EWAQLYEQKQQFAQA--
MMAR_2618|M.marinum_M               -----------------
MUL_3143|M.ulcerans_Agy99           -----------------
MAV_2993|M.avium_104                -----------------