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M. thermoresistible (build 8) TH_2339 (-)

annotation: amidohydrolase 2
coordinates: 4595073 - 4596350
length: 426

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2339--100% (426)amidohydrolase 2
M. thermoresistible (build 8)TH_2017-6e-2456.18% (89) amidohydrolase 2
M. thermoresistible (build 8)TH_2827-4e-1923.82% (361) PUTATIVE amidohydrolase 2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2371-0.091.11% (416) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4742-1e-11849.14% (405) metal-dependent amidohydrolase
M. avium 104MAV_0860-0.090.95% (420) amidohydrolase 2
M. smegmatis MC2 155MSMEG_6547-0.091.35% (416) amidohydrolase 2
M. ulcerans Agy99MUL_3143-5e-7039.52% (372) amidohydrolase
M. vanbaalenii PYR-1Mvan_4275-0.091.69% (421) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2371|M.gilvum_PYR-GCK          -----MREDDLILVSIDDHVVEPPDMFLRHVPEKYKEEAPIVVTDEKGVD
Mvan_4275|M.vanbaalenii_PYR-1       -----MQTDDLILVSIDDHVVEPPDMFLRHVPAKYREEAPIVVTDDKGVD
MSMEG_6547|M.smegmatis_MC2_155      -----MQTDDLILVSIDDHVVEPPDMFLRHVPAKYRDEAPIVVTDEKGVD
MAV_0860|M.avium_104                -----MKADDLILVSIDDHVVEPPDMFLRHVPAKYRDEAPIVVTDDKGVD
TH_2339|M.thermoresistible__bu      -MSHDLRPEDLILVSIDDHVVEPPDMFLRHVPAKYRDEAPIVVTDENGVD
MMAR_4742|M.marinum_M               -----MNKEDMILISVDDHTVEPPNMFKNHLSAKYLDDAPRLVHNPDGSD
MUL_3143|M.ulcerans_Agy99           MTDPPRARRRYTVISVDDHIVEPPDTFTGRLPQRFADRAPRVVETDDGGQ
                                                ::*:*** ****: *  ::. :: : ** :*   .* :

Mflv_2371|M.gilvum_PYR-GCK          QWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVYDVHERVRDMN
Mvan_4275|M.vanbaalenii_PYR-1       QWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVYDVHERVRDMN
MSMEG_6547|M.smegmatis_MC2_155      QWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVYDVHERVRDMN
MAV_0860|M.avium_104                QWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVYDVHERVRDMN
TH_2339|M.thermoresistible__bu      QWMYQGRPQGVSGLNAVVSWPPEEWGRNPARFAEMRPGVYDVHERVRDMN
MMAR_4742|M.marinum_M               MWKFRDTVIPNVALNAVAGRPKEEYGLEPQGLDEIRPGCYNVDERIKDMN
MUL_3143|M.ulcerans_Agy99           VWVYDGQVLPNVGFNAVVGRPVSEYGFEPVRFDEMRRGAWDIHERIKDMD
                                     * : .      .:***.. * .*:* :*  : *:* * :::.**::**:

Mflv_2371|M.gilvum_PYR-GCK          RNGILASMCFPTFT-GFSARHLN--MTREDVTLVMVSAYNDWHIDEWAGS
Mvan_4275|M.vanbaalenii_PYR-1       RNGILASMCFPTFT-GFSARHLN--MHREEATLVMVSAYNDWHIDEWAGS
MSMEG_6547|M.smegmatis_MC2_155      RNGILASMCFPTFT-GFSARHLN--MHREEATLVMVSAYNDWHIDEWAGS
MAV_0860|M.avium_104                RNGILASMCFPTFT-GFSARHLN--MHREEVTLVMVSAYNDWHIDEWAGS
TH_2339|M.thermoresistible__bu      RNGILASMCFPTFT-GFSARHLN--MHREHVTLIMVSAYNDWHIDEWAGS
MMAR_4742|M.marinum_M               AGGILASICFPSFP-GFAGRLFA--TEDPDFSVALVQAYNDWHIDEWCGA
MUL_3143|M.ulcerans_Agy99           LNGVYASLNFPSFLPGFAGQRLQQVTKDPELAWAAVRAWNDWHLEAWAGP
                                     .*: **: **:*  **:.: :       . :   * *:****:: *.*.

Mflv_2371|M.gilvum_PYR-GCK          YPDRFIPIAILPTWTPEGMCNEIRRVAAKGCRAVTMPELPHLEGLPSYHD
Mvan_4275|M.vanbaalenii_PYR-1       YPDRFIPIAILPTWNVEAMCAEIRRVAAKGCRAVTMPELPHLEGLPSYHD
MSMEG_6547|M.smegmatis_MC2_155      YPDRFIPIAILPTWNPEAMCREIRRVAAKGCRAVTMPELPHLEGLPSYHD
MAV_0860|M.avium_104                YPDRFIPIAILPTWNPEAMCAEIRRVAAKGCRAVTMPELPHLEGLPSYHD
TH_2339|M.thermoresistible__bu      YPGRFIPIAILPTWNPEAMCAEIRRVAAKGCRAVTMPELPHLEGLPSYHD
MMAR_4742|M.marinum_M               YPARFVPMAIPVIWDAEACAAEVRRVAKKGVHALTFTENPAAMGYPSFHN
MUL_3143|M.ulcerans_Agy99           YPERIIPCQLPWLLDPSAGAQLIHENAERGFRAVSFSENPAMLGLPSIHS
                                    ** *::*  :      .. .  ::. * :* :*:::.* *   * ** *.

Mflv_2371|M.gilvum_PYR-GCK          EDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPNAPIDNLIILATQVSAM
Mvan_4275|M.vanbaalenii_PYR-1       DDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPNAPIDNLIILATQVSAM
MSMEG_6547|M.smegmatis_MC2_155      DDYWGPVFTTLSEENVVMCLHIGTGFGAISMAPNAPIDNLIILATQVSAM
MAV_0860|M.avium_104                EDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPNAPIDNMIILATQVSAM
TH_2339|M.thermoresistible__bu      EDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPDAPIDNMIILATQVSAM
MMAR_4742|M.marinum_M               -EYWNPLWKALCDTNTVMNIHIGSSGRLAITAPDAPMDVMITLQPMNIVQ
MUL_3143|M.ulcerans_Agy99           -GHWDPMMAACAETGTVVNLHIGSSGSSPSTTDDAPADVPGVLFFAYAIS
                                      :*.*:  : .: ..*: :***:.      : :** *    *       

Mflv_2371|M.gilvum_PYR-GCK          CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDRHYTNQ--KWLRR
Mvan_4275|M.vanbaalenii_PYR-1       CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDRHYTNQ--KWLRR
MSMEG_6547|M.smegmatis_MC2_155      CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDRHYTNQ--KWLRR
MAV_0860|M.avium_104                CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDRHYSNQ--KWLRR
TH_2339|M.thermoresistible__bu      CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRCDRHYTNQ--KWLRR
MMAR_4742|M.marinum_M               AAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERADRTFEMHS-TWTHQ
MUL_3143|M.ulcerans_Agy99           AAVDWLYSGLPSRFPDLKICLSEGRIGWVAGLLDRLDHMLSYHEMYGTWR
                                    .* * *:.    .:****:.:***  **:.  *:* *:    :      :

Mflv_2371|M.gilvum_PYR-GCK          DFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
Mvan_4275|M.vanbaalenii_PYR-1       DFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
MSMEG_6547|M.smegmatis_MC2_155      DFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
MAV_0860|M.avium_104                DFGSQLP-SEVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
TH_2339|M.thermoresistible__bu      DFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
MMAR_4742|M.marinum_M               NFGGKIP-SEVFREHFLTCFISDKVGVALRNMIGIDNIAWEADYPHSDSM
MUL_3143|M.ulcerans_Agy99           AMGESLTSAEVFTRNFWFCAVEDKSSFVQHYRIGTENIMVESDYPHCDST
                                     :* .:. ::** .:   * : ** ..  :  ** : *  *.****.*. 

Mflv_2371|M.gilvum_PYR-GCK          WPDAPEQVLAELNAAGASDSDINKITWQNSCRFFGWDPFKLTPRDQATAG
Mvan_4275|M.vanbaalenii_PYR-1       WPDAPEKVLAELNAAGASDSDINKITWENSCRFFSWDPFKLTPKEQATAG
MSMEG_6547|M.smegmatis_MC2_155      WPDAPEQVLAELNAAGASDSDIHKITWENACRFFSWDPFARTAREEATVK
MAV_0860|M.avium_104                WPDAPEQVLAELTAAGADDADINKITWANACRFFSWDPFARTPRDQATVK
TH_2339|M.thermoresistible__bu      WPDAPEQVHAELRAAGADDFDINKITWENSCRFFSWDPFEHTPRAEATVG
MMAR_4742|M.marinum_M               WPGAPEELWDVLSVNDVPDGEINKMTYENAMRWYSFDPFSHITREQATVG
MUL_3143|M.ulcerans_Agy99           WPHTQQTMHEQL--DGLPADVIRKITWENAARLYQHPVPVAIAQNPEAF-
                                    ** : : :   *   .     *.*:*: *: * :        .:   :  

Mflv_2371|M.gilvum_PYR-GCK          ALRAKAADVDTSIRPR-----AEWARLYHEK-QLTKA------
Mvan_4275|M.vanbaalenii_PYR-1       ALRAKATDVDTSIRPR-----AEWARLYNEKQQFAQA------
MSMEG_6547|M.smegmatis_MC2_155      ALRAKGSDVDVSIRSR-----AEWRRLYEEK-QLAKA------
MAV_0860|M.avium_104                ALRAKALDVDVSIRSR-----AEWARRYHEKQLAGQT------
TH_2339|M.thermoresistible__bu      ALRAKATDVDTTIRSR-----AEWAQLYEQKQQFAQA------
MMAR_4742|M.marinum_M               ALRKAAEGHDVSVRALSHHKDARSGSSVAEFTANAKALTGNKD
MUL_3143|M.ulcerans_Agy99           -------------------------------------------