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TDPPRARRRYTVISVDDHIVEPPDTFTGRLPQRFADRAPRVVETDDGGQVWVYDGQVLPNVGFNAVVGRP VSEYGFEPVRFDEMRRGAWDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQVTKDPELAWAAVRAWND WHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIHENAERGFRAVSFSENPAMLGLPSIHSGHWDPMMAACA ETGTVVNLHIGSSGSSPSTTDDAPADVPGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSEGRIGWVAGL LDRLDHMLSYHEMYGTWRAMGESLTSAEVFTRNFWFCAVEDKSSFVQHYRIGTENIMVESDYPHCDSTWP HTQQTMHEQLDGLPADVIRKITWENAARLYQHPVPVAIAQNPEAF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3143 | - | - | 100% (396) | amidohydrolase |
| M. ulcerans Agy99 | MUL_0389 | - | 5e-29 | 28.80% (309) | hypothetical protein MUL_0389 |
| M. ulcerans Agy99 | MUL_3878 | - | 2e-16 | 26.13% (398) | metal-dependent hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2441 | - | 9e-93 | 46.38% (373) | amidohydrolase 2 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2618 | - | 0.0 | 98.99% (396) | amidohydrolase |
| M. avium 104 | MAV_2993 | - | 0.0 | 84.34% (396) | amidohydrolase 2 |
| M. smegmatis MC2 155 | MSMEG_4837 | - | 3e-86 | 44.92% (374) | amidohydrolase 2 |
| M. thermoresistible (build 8) | TH_2339 | - | 5e-70 | 39.52% (372) | amidohydrolase 2 |
| M. vanbaalenii PYR-1 | Mvan_4211 | - | 1e-91 | 45.84% (373) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2441|M.gilvum_PYR-GCK -------------------------------MDKNDMILISVDDHIVEPP
Mvan_4211|M.vanbaalenii_PYR-1 ---------------MSRAPARKGGNGRSAVMNRDDMILISVDDHIVEPP
MSMEG_4837|M.smegmatis_MC2_155 -------------------------------MNKDDMILISVDDHIIEPP
TH_2339|M.thermoresistible__bu ---------------------------MSHDLRPEDLILVSIDDHVVEPP
MUL_3143|M.ulcerans_Agy99 --------------------------MTDPPRARRRYTVISVDDHIVEPP
MMAR_2618|M.marinum_M MKSIDELASDLSFTTAKTGADRSVTFLPDPPRARRRYTVISVDDHIVEPP
MAV_2993|M.avium_104 MKSIDELATDLNFTTAKTGAQRTVTLLPDPPRAPRRYTLISVDDHIVEPP
::*:***::***
Mflv_2441|M.gilvum_PYR-GCK DMFKNHLSKKYLDEAPRLVHNEDGSDTWQFRDVVIPNVALNAVAGRPKEE
Mvan_4211|M.vanbaalenii_PYR-1 DMFKNHLPRKYLDEAPRLVHNPDGSDTWQFRDVVIPNVALNAVAGRPKEE
MSMEG_4837|M.smegmatis_MC2_155 DMFKNHLPAKYRDEAPRLVHNPDGSDTWQFRDTVIPNVALNAVAGRPKEE
TH_2339|M.thermoresistible__bu DMFLRHVPAKYRDEAPIVVTDENGVDQWMYQGRPQGVSGLNAVVSWPPEE
MUL_3143|M.ulcerans_Agy99 DTFTGRLPQRFADRAPRVVETDDGGQVWVYDGQVLPNVGFNAVVGRPVSE
MMAR_2618|M.marinum_M DTFTGRLPQRFADRAPRVVETDDGGQVWVYDGQVLPNVGFNAVVGRPVSE
MAV_2993|M.avium_104 DTFAGRVPRKFADRAPCVVDTDTGGQTWVYDGRQLPNVGFNAVVGRPVAE
* * ::. :: *.** :* * : * : . .:***.. * *
Mflv_2441|M.gilvum_PYR-GCK YGLEPQGLDEIRPGCWQVDERVKDMNAGGILGSMCFPSFP-GFAGRLFA-
Mvan_4211|M.vanbaalenii_PYR-1 YGLEPQGLDEIRPGCWQVDERVKDMNAGGILGSMCFPSFP-GFAGRLFA-
MSMEG_4837|M.smegmatis_MC2_155 YGLEPQGLDEIRKGCYDPNERVKDMNAGGVLATMNFPSFP-GFAARLFA-
TH_2339|M.thermoresistible__bu WGRNPARFAEMRPGVYDVHERVRDMNRNGILASMCFPTFT-GFSARHLN-
MUL_3143|M.ulcerans_Agy99 YGFEPVRFDEMRRGAWDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQ
MMAR_2618|M.marinum_M YGFEPVRFDEMRRGAWDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQ
MAV_2993|M.avium_104 YGFEPVRFDEMRRGAWDIHERVKDMDLNGVYASLNFPSFLPGFAGQRLQQ
:* :* : *:* * :: .**::**: .*: .:: **:* **:.: :
Mflv_2441|M.gilvum_PYR-GCK -TEDPEFSLALVQAYNDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIR
Mvan_4211|M.vanbaalenii_PYR-1 -TEDAEFSLALVQAYNDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIR
MSMEG_4837|M.smegmatis_MC2_155 -TDDEEFSLALVQAYNDWHIDEWCASNPGRFIPMAIPAIWNPGLAAAEVR
TH_2339|M.thermoresistible__bu -MHREHVTLIMVSAYNDWHIDEWAGSYPGRFIPIAILPTWNPEAMCAEIR
MUL_3143|M.ulcerans_Agy99 VTKDPELAWAAVRAWNDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIH
MMAR_2618|M.marinum_M VTKDPELAWAAVRAWNDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIH
MAV_2993|M.avium_104 LTDDRDLALACVRAWNDWHFEVWAGSYPDRIIPCQLPWLLDPELGAKMIY
. ..: * *:****.: *... * *:** : :* . :
Mflv_2441|M.gilvum_PYR-GCK RNAARGVHSLTFSENPSAMGYPSFHDFDHWKPMWDALVDTDTVLNVHIGS
Mvan_4211|M.vanbaalenii_PYR-1 RNAARGVHSLTFSENPSAMGYPSFHDFEHWKPMWDALVDTDTVLNVHIGS
MSMEG_4837|M.smegmatis_MC2_155 RVAEKGVHSLTFTENPSTLGYPSFHDLEYWRPLWQALVDTETVMNVHIGS
TH_2339|M.thermoresistible__bu RVAAKGCRAVTMPELPHLEGLPSYHDEDYWGPVFRTLSEENVVMCLHIGT
MUL_3143|M.ulcerans_Agy99 ENAERGFRAVSFSENPAMLGLPSIHSG-HWDPMMAACAETGTVVNLHIGS
MMAR_2618|M.marinum_M ENAERGFRAVSFSENPAMLGLPSIHSG-HWDPMMAACAETGTVVNLHIGS
MAV_2993|M.avium_104 ENAERGFHAVTFSENPAMLGLPSIHTG-HWDPMMAACAETGTVVNLHIGS
. * :* :::::.* * * ** * :* *: : : .*: :***:
Mflv_2441|M.gilvum_PYR-GCK SGRLAITAPDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEG
Mvan_4211|M.vanbaalenii_PYR-1 SGRLAITAPDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEG
MSMEG_4837|M.smegmatis_MC2_155 SGKLAITAPDAPMDVMITLQPMNIVQAAADLLWSAPIKEFPTLKIALSEG
TH_2339|M.thermoresistible__bu GFGAISMAPDAPIDNMIILATQVSAMCAQDLLWGPAMRNYPDLKFAFSEG
MUL_3143|M.ulcerans_Agy99 SGSSPSTTDDAPADVPGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSEG
MMAR_2618|M.marinum_M SGSSPSTTDDAPADVPGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSEG
MAV_2993|M.avium_104 SGSSPSTTADAPPDVQGVLFFAYAISAAVDWLYSGLPSRFPNLKICLSEG
. : *** * * .* * *:. .:* **:.:***
Mflv_2441|M.gilvum_PYR-GCK GTGWIPYFLERVDRTYEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIADP
Mvan_4211|M.vanbaalenii_PYR-1 GTGWIPYFLERVDRTYEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIADP
MSMEG_4837|M.smegmatis_MC2_155 GTGWIPYFLDRVDRTFEMHSTWTH-QNFGGKLP-SEVFREHFMTCFISDP
TH_2339|M.thermoresistible__bu GIGWIPFYLDRCDRHYTN-QKWLR-RDFGDKLP-SDVFREHSLACYVTDK
MUL_3143|M.ulcerans_Agy99 RIGWVAGLLDRLDHMLSYHEMYGTWRAMGESLTSAEVFTRNFWFCAVEDK
MMAR_2618|M.marinum_M GIGWVAGLLDRLDHMLSYHEMYGTWRAMGESLTPAEVFTRNFWFCAVEDK
MAV_2993|M.avium_104 GIGWVAGLLDRLDHMLSYHAMYGTWQALGERLTPAEVLVRNFWFCAVEDK
**:. *:* *: : : : *. ::*: .: * : *
Mflv_2441|M.gilvum_PYR-GCK VGVATRHQIGVDNICWEADYPHSDSMWPGAPEQLDEVLKANNVPDDEINK
Mvan_4211|M.vanbaalenii_PYR-1 VGVATRHQIGVDNICWEADYPHSDSMWPGAPEQLDEVLKVNSVPDDEIDK
MSMEG_4837|M.smegmatis_MC2_155 VGVKNRHMIGIDNICWEMDYPHSDSMWPGAPEELSAVFDTYDVPDDEINK
TH_2339|M.thermoresistible__bu TSLKLRHEIGIDIIAWECDYPHSDCFWPDAPEQVHAELRAAGADDFDINK
MUL_3143|M.ulcerans_Agy99 SSFVQHYRIGTENIMVESDYPHCDSTWPHTQQTMHEQLDG--LPADVIRK
MMAR_2618|M.marinum_M SSFVQHHRIGTENIMVESDYPHCDSTWPHTQQTMHEQLDG--LPADVIRK
MAV_2993|M.avium_104 SSFVQRDRIGVDNIMLEADYPHCDSTWPHTQQTVHEQIGG--LPADVIRK
.. : ** : * * ****.*. ** : : : : * *
Mflv_2441|M.gilvum_PYR-GCK MTYENAMRWYHWDPFTHIAKEQATVGALRKAAEGHDVSIQALSNKEKTGT
Mvan_4211|M.vanbaalenii_PYR-1 MTYQNAMRWYHWDPFTHIPKEQATVGALRKAAEGHDVSIQALSHKEKTGA
MSMEG_4837|M.smegmatis_MC2_155 ITHENAMRLYHFDPFAHVPKEQATVGALRKAAEGHDVSIRALSKKDKTGA
TH_2339|M.thermoresistible__bu ITWENSCRFFSWDPFEHTPRAEATVGALRAKATDVDTTIRSR-------A
MUL_3143|M.ulcerans_Agy99 ITWENAARLYQHPVPVAIAQNPEAF-------------------------
MMAR_2618|M.marinum_M ITWENAARLYQHPVPVAIAQNPEAF-------------------------
MAV_2993|M.avium_104 FTWQNASRLYQHPVPIQVQQNPDAF-------------------------
:* :*: * : : :.
Mflv_2441|M.gilvum_PYR-GCK TFSDFAASAKSISGNKD
Mvan_4211|M.vanbaalenii_PYR-1 TFADFAARAKEITGNTD
MSMEG_4837|M.smegmatis_MC2_155 SFADFQANAKAVSGARD
TH_2339|M.thermoresistible__bu EWAQLYEQKQQFAQA--
MUL_3143|M.ulcerans_Agy99 -----------------
MMAR_2618|M.marinum_M -----------------
MAV_2993|M.avium_104 -----------------