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M. marinum M MMAR_4742 (-)

annotation: metal-dependent amidohydrolase
coordinates: 5792084 - 5793382
length: 432

NKEDMILISVDDHTVEPPNMFKNHLSAKYLDDAPRLVHNPDGSDMWKFRDTVIPNVALNAVAGRPKEEYG
LEPQGLDEIRPGCYNVDERIKDMNAGGILASICFPSFPGFAGRLFATEDPDFSVALVQAYNDWHIDEWCG
AYPARFVPMAIPVIWDAEACAAEVRRVAKKGVHALTFTENPAAMGYPSFHNEYWNPLWKALCDTNTVMNI
HIGSSGRLAITAPDAPMDVMITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERADRTF
EMHSTWTHQNFGGKIPSEVFREHFLTCFISDKVGVALRNMIGIDNIAWEADYPHSDSMWPGAPEELWDVL
SVNDVPDGEINKMTYENAMRWYSFDPFSHITREQATVGALRKAAEGHDVSVRALSHHKDARSGSSVAEFT
ANAKALTGNKD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4742--100% (432)metal-dependent amidohydrolase
M. marinum MMMAR_0273-0.084.25% (419) amidohydrolase
M. marinum MMMAR_2618-4e-8844.09% (372) amidohydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2441-0.080.14% (433) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. avium 104MAV_0907-0.091.44% (432) amidohydrolase 2
M. smegmatis MC2 155MSMEG_4837-0.079.21% (433) amidohydrolase 2
M. thermoresistible (build 8)TH_2339-1e-11849.14% (405) amidohydrolase 2
M. ulcerans Agy99MUL_3143-2e-8643.97% (373) amidohydrolase
M. vanbaalenii PYR-1Mvan_4211-0.080.37% (433) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_4742|M.marinum_M               ----------------MNKEDMILISVDDHTVEPPNMFKNHLSAKYLDDA
MAV_0907|M.avium_104                ----------------MNKEDMILISVDDHTVEPPDMFKNHLPKKYLDDA
Mflv_2441|M.gilvum_PYR-GCK          ----------------MDKNDMILISVDDHIVEPPDMFKNHLSKKYLDEA
Mvan_4211|M.vanbaalenii_PYR-1       MSRAPARKGGNGRSAVMNRDDMILISVDDHIVEPPDMFKNHLPRKYLDEA
MSMEG_4837|M.smegmatis_MC2_155      ----------------MNKDDMILISVDDHIIEPPDMFKNHLPAKYRDEA
TH_2339|M.thermoresistible__bu      ------------MSHDLRPEDLILVSIDDHVVEPPDMFLRHVPAKYRDEA
MUL_3143|M.ulcerans_Agy99           -----------MTDPPRARRRYTVISVDDHIVEPPDTFTGRLPQRFADRA
                                                           ::*:*** :***: *  ::. :: * *

MMAR_4742|M.marinum_M               PRLVHNPDGSDMWKFRDTVIPNVALNAVAGRPKEEYGLEPQGLDEIRPGC
MAV_0907|M.avium_104                PRLVHNPDGSDMWKFRDTVIPNVALNAVAGRPKEEYGIEPTGLDEIRPGC
Mflv_2441|M.gilvum_PYR-GCK          PRLVHNEDGSDTWQFRDVVIPNVALNAVAGRPKEEYGLEPQGLDEIRPGC
Mvan_4211|M.vanbaalenii_PYR-1       PRLVHNPDGSDTWQFRDVVIPNVALNAVAGRPKEEYGLEPQGLDEIRPGC
MSMEG_4837|M.smegmatis_MC2_155      PRLVHNPDGSDTWQFRDTVIPNVALNAVAGRPKEEYGLEPQGLDEIRKGC
TH_2339|M.thermoresistible__bu      PIVVTDENGVDQWMYQGRPQGVSGLNAVVSWPPEEWGRNPARFAEMRPGV
MUL_3143|M.ulcerans_Agy99           PRVVETDDGGQVWVYDGQVLPNVGFNAVVGRPVSEYGFEPVRFDEMRRGA
                                    * :*   :* : * : .      .:***.. * .*:* :*  : *:* * 

MMAR_4742|M.marinum_M               YNVDERIKDMNAGGILASICFPSFP-GFAGR--LFATEDPDFSVALVQAY
MAV_0907|M.avium_104                YNVDERVKDMNAGGILASICFPSFP-GFAGR--LFATEDNDFSIALVQAY
Mflv_2441|M.gilvum_PYR-GCK          WQVDERVKDMNAGGILGSMCFPSFP-GFAGR--LFATEDPEFSLALVQAY
Mvan_4211|M.vanbaalenii_PYR-1       WQVDERVKDMNAGGILGSMCFPSFP-GFAGR--LFATEDAEFSLALVQAY
MSMEG_4837|M.smegmatis_MC2_155      YDPNERVKDMNAGGVLATMNFPSFP-GFAAR--LFATDDEEFSLALVQAY
TH_2339|M.thermoresistible__bu      YDVHERVRDMNRNGILASMCFPTFT-GFSAR--HLNMHREHVTLIMVSAY
MUL_3143|M.ulcerans_Agy99           WDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQVTKDPELAWAAVRAW
                                    :: .**::**: .*: .:: **:*  **:.:      .  ..:   * *:

MMAR_4742|M.marinum_M               NDWHIDEWCGAYPARFVPMAIPVIWDAEACAAEVRRVAKKGVHALTFTEN
MAV_0907|M.avium_104                NDWHIDEWCGAYPARFIPMAIPVIWDAEECAKEVRRVSKKGVHALTFTEN
Mflv_2441|M.gilvum_PYR-GCK          NDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIRRNAARGVHSLTFSEN
Mvan_4211|M.vanbaalenii_PYR-1       NDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIRRNAARGVHSLTFSEN
MSMEG_4837|M.smegmatis_MC2_155      NDWHIDEWCASNPGRFIPMAIPAIWNPGLAAAEVRRVAEKGVHSLTFTEN
TH_2339|M.thermoresistible__bu      NDWHIDEWAGSYPGRFIPIAILPTWNPEAMCAEIRRVAAKGCRAVTMPEL
MUL_3143|M.ulcerans_Agy99           NDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIHENAERGFRAVSFSEN
                                    ****:: *... * *::*  :    :.   .  ::. : :* :::::.* 

MMAR_4742|M.marinum_M               PAAMGYPSFHN-EYWNPLWKALCDTNTVMNIHIGSSGRLAITAPDAPMDV
MAV_0907|M.avium_104                PAAMGYPSFHD-EYWNPLWKALVDTNTVMNVHIGSSGRLAITAPDAPMDV
Mflv_2441|M.gilvum_PYR-GCK          PSAMGYPSFHDFDHWKPMWDALVDTDTVLNVHIGSSGRLAITAPDAPMDV
Mvan_4211|M.vanbaalenii_PYR-1       PSAMGYPSFHDFEHWKPMWDALVDTDTVLNVHIGSSGRLAITAPDAPMDV
MSMEG_4837|M.smegmatis_MC2_155      PSTLGYPSFHDLEYWRPLWQALVDTETVMNVHIGSSGKLAITAPDAPMDV
TH_2339|M.thermoresistible__bu      PHLEGLPSYHDEDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPDAPIDN
MUL_3143|M.ulcerans_Agy99           PAMLGLPSIHS-GHWDPMMAACAETGTVVNLHIGSSGSSPSTTDDAPADV
                                    *   * ** *.  :* *:  :  :  .*: :***:.      : *** * 

MMAR_4742|M.marinum_M               MITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERADRT
MAV_0907|M.avium_104                MITLQPMNIVQAAADLLWSRPIKEFPDLKIALSEGGTGWIPYFLERADRT
Mflv_2441|M.gilvum_PYR-GCK          MITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERVDRT
Mvan_4211|M.vanbaalenii_PYR-1       MITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERVDRT
MSMEG_4837|M.smegmatis_MC2_155      MITLQPMNIVQAAADLLWSAPIKEFPTLKIALSEGGTGWIPYFLDRVDRT
TH_2339|M.thermoresistible__bu      MIILATQVSAMCAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRCDRH
MUL_3143|M.ulcerans_Agy99           PGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSEGRIGWVAGLLDRLDHM
                                       *       .* * *:.    .:* **:.:***  **:.  *:* *: 

MMAR_4742|M.marinum_M               FEMHSTWTH-QNFGGKIP-SEVFREHFLTCFISDKVGVALRNMIGIDNIA
MAV_0907|M.avium_104                FEMHSAWTH-QDFKGKLP-SEVFREHFLTCFISDKVGVALRNEIGIDNIC
Mflv_2441|M.gilvum_PYR-GCK          YEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIADPVGVATRHQIGVDNIC
Mvan_4211|M.vanbaalenii_PYR-1       YEMHSTWTG-QDFKGKLP-SEVFREHFLTCFIADPVGVATRHQIGVDNIC
MSMEG_4837|M.smegmatis_MC2_155      FEMHSTWTH-QNFGGKLP-SEVFREHFMTCFISDPVGVKNRHMIGIDNIC
TH_2339|M.thermoresistible__bu      YTN-QKWLR-RDFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIA
MUL_3143|M.ulcerans_Agy99           LSYHEMYGTWRAMGESLTSAEVFTRNFWFCAVEDKSSFVQHYRIGTENIM
                                        . :   : :  .:. ::** .:   * : *  ..  :  ** : * 

MMAR_4742|M.marinum_M               WEADYPHSDSMWPGAPEELWDVLSVNDVPDGEINKMTYENAMRWYSFDPF
MAV_0907|M.avium_104                WEADYPHSDSMWPGAPEELWDVLSINNVPDDEINKMTYQNAMRWYSFDPF
Mflv_2441|M.gilvum_PYR-GCK          WEADYPHSDSMWPGAPEQLDEVLKANNVPDDEINKMTYENAMRWYHWDPF
Mvan_4211|M.vanbaalenii_PYR-1       WEADYPHSDSMWPGAPEQLDEVLKVNSVPDDEIDKMTYQNAMRWYHWDPF
MSMEG_4837|M.smegmatis_MC2_155      WEMDYPHSDSMWPGAPEELSAVFDTYDVPDDEINKITHENAMRLYHFDPF
TH_2339|M.thermoresistible__bu      WECDYPHSDCFWPDAPEQVHAELRAAGADDFDINKITWENSCRFFSWDPF
MUL_3143|M.ulcerans_Agy99           VESDYPHCDSTWPHTQQTMHEQLDG--LPADVIRKITWENAARLYQHPVP
                                     * ****.*. ** : : :   :         * *:* :*: * :     

MMAR_4742|M.marinum_M               SHITREQATVGALRKAAEGHDVSVRALSHHKDARSGSSVAEFTANAKALT
MAV_0907|M.avium_104                THISREQATVGALRKAAEGHDVSIKAQGHDKDSRGGSSFAEFAANAKALT
Mflv_2441|M.gilvum_PYR-GCK          THIAKEQATVGALRKAAEGHDVSIQALSNKE--KTGTTFSDFAASAKSIS
Mvan_4211|M.vanbaalenii_PYR-1       THIPKEQATVGALRKAAEGHDVSIQALSHKE--KTGATFADFAARAKEIT
MSMEG_4837|M.smegmatis_MC2_155      AHVPKEQATVGALRKAAEGHDVSIRALSKKD--KTGASFADFQANAKAVS
TH_2339|M.thermoresistible__bu      EHTPRAEATVGALRAKATDVDTTIRSR---------AEWAQLYEQKQQFA
MUL_3143|M.ulcerans_Agy99           VAIAQNPEAF----------------------------------------
                                       .:   :.                                        

MMAR_4742|M.marinum_M               GNKD
MAV_0907|M.avium_104                GNKD
Mflv_2441|M.gilvum_PYR-GCK          GNKD
Mvan_4211|M.vanbaalenii_PYR-1       GNTD
MSMEG_4837|M.smegmatis_MC2_155      GARD
TH_2339|M.thermoresistible__bu      QA--
MUL_3143|M.ulcerans_Agy99           ----