For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSRATSLRRQHGDGDQEFASAVAIIGVACRFPGAANPGEFWELVSEGHEVAKPIDHVGDFDAEFFNVSPR EAAAMDPRQRLALELAWELFEDARIVAESVRGEPIAVYLGAMNDDYALLTLDQAPDKLDHYSFAGASRGM IANRVSYGFALHGPSMTVDCGQSSSLVAVHLAREYLRGAGDATMAIAGGIHLNLASETGRLETEFGAVSA SGRTYAFDARADGYVRSEGGGLVLLKPLRAALEDGNRIRAVILGAAVGSAGHTAGGLAAPSAAAEADVMR RAMASAGVDPNQIDYIEAHGTGTRIGDTTEAQALSEVFATRETPVWLGSVKSNIGHTGAAAGAAGLIKTV LSLENGAIPASLNYVGDSAGTDMESHGLHVSTTLTPWPRGAGPRRAGVSSFGMGGTNAHVIVQQAPIPQE AVADPDGTEATVPWLVSARSRAALAGQAQRLAAWVAELPSIDVADVGWSLLSTRSVFEHRAVLVGGDRGG FMAGLAALASGEPGVNLVAGRAGSGGKTVLVFPGQGAQWLGMGRDLYGRFPAFAKAFDTVADALDEHLRL PLREVIWGADASLLEGTEFAQPALFALEVALAALLQACGVVADLVMGHSVGEISAAHVAGVLSLTDAARL VSARGRLMAQLPPGGVMVAVAASAAQVAPMLEEGVSIAAVNGPDSVVISGPEAATAVVADRLTGQGCRAH RLAVSHAFHSALMEPMMAQFGATISGIVAHEPRIALVSTMTGQLAAAGYGTASYWVEHVRKPVRFADGVA LAESLGAATFLETGPSAGLGTSVALLAKGRPEVESLLTAMGQLYVDGADLDWRAAFAGLRARTVTLPTYS FARQRFWLGEGAGRKADSSDESGLRPRLDSVDSKERFRQLVDLVCLHAAIVTGHSNSHQIDAERAFQDLG FESMTGVELRNRLRAVTGLALSRTIIFDYPTPMALARHLDEQLSGGNHEESDDDKIWSVLRTIPVRELRR SGMLDKLLLLAGQDESPAPDAAVSDDVIDSLSPEALVAMALDSEDDDPD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2473 | pks9 | - | 100% (1029) | polyketide synthase Pks9 |
| M. marinum M | MMAR_2472 | pks8 | 0.0 | 51.41% (887) | polyketide synthase, Pks8 |
| M. marinum M | MMAR_0707 | pks6 | 0.0 | 45.22% (1035) | polyketide synthase Pks6 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1692 | pks9 | 0.0 | 63.56% (1018) | polyketide synthase pks9 |
| M. gilvum PYR-GCK | Mflv_0405 | - | 1e-157 | 38.80% (897) | beta-ketoacyl synthase |
| M. tuberculosis H37Rv | Rv1664 | pks9 | 0.0 | 63.65% (1018) | polyketide synthase pks9 |
| M. leprae Br4923 | MLBr_00135 | - | 0.0 | 45.30% (894) | putative polyketide synthase |
| M. abscessus ATCC 19977 | MAB_0939 | - | 1e-157 | 39.13% (892) | polyketide synthase |
| M. avium 104 | MAV_3107 | - | 0.0 | 62.22% (1027) | polyketide synthase |
| M. smegmatis MC2 155 | MSMEG_0408 | - | 1e-155 | 38.29% (888) | type I modular polyketide synthase |
| M. thermoresistible (build 8) | TH_4458 | - | 1e-142 | 34.44% (1080) | PUTATIVE putative Fatty acyl-AMP ligase FadD28_1 and polyketide |
| M. ulcerans Agy99 | MUL_1655 | pks9 | 0.0 | 98.54% (1029) | polyketide synthase Pks9 |
| M. vanbaalenii PYR-1 | Mvan_1003 | - | 1e-159 | 39.05% (909) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0405|M.gilvum_PYR-GCK --------------MGSAAHQGE-SAHRFAIVGYAGRFPGARDAESFWEL
MAB_0939|M.abscessus_ATCC_1997 --------------MDSAENPIE-STPRFAIIGYAARFPGAADAEEFWDV
MSMEG_0408|M.smegmatis_MC2_155 --------------MVSAEHPIE-PTPSFAIIGYAARFPGAASAEEYWAL
Mvan_1003|M.vanbaalenii_PYR-1 MTDLQKRALQAIEVLRARVRELEGAGDGYAIVGYALRFPGAADADEFWDV
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LADGRDAISEVPEDRWDVEAFFDPDPSTPGKVVTRRAGFVDDVSGFDAPF
MAB_0939|M.abscessus_ATCC_1997 LREGRDAISEVPADRWDAEEFFDPEPGAPGKVVTRRAGFVEDVTGFDAPF
MSMEG_0408|M.smegmatis_MC2_155 LRDGREAISDVPKDRWDIEEFFDPDPSTPGKVVTRRAGFVDDVTGFDAPF
Mvan_1003|M.vanbaalenii_PYR-1 LRGGRDAISEVPQDRWDADEFFDADPEAAGKMVTRRAGFVEDVAGFDAPF
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK FGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSELANTNTGVFVGLATH
MAB_0939|M.abscessus_ATCC_1997 FGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTDLAETNSGVFVGLATH
MSMEG_0408|M.smegmatis_MC2_155 FGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTSLANSNTGVFVGLATH
Mvan_1003|M.vanbaalenii_PYR-1 FGVSAREAMFMDPQHRLLLETAWRAVEHSGTAPSALAGTRTGVFMGLSTH
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK DYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACS
MAB_0939|M.abscessus_ATCC_1997 DYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAVDTACS
MSMEG_0408|M.smegmatis_MC2_155 DYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACS
Mvan_1003|M.vanbaalenii_PYR-1 DYLGMLTDNLTHDAIEAYLGTGTSPAAAIGRISYRLGLQGPAVAVDTACS
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK SSLVAIHQACQALRLGECDLALAGGANVILTPATMITFSNAHMLAPDGRC
MAB_0939|M.abscessus_ATCC_1997 SSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKC
MSMEG_0408|M.smegmatis_MC2_155 SSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRC
Mvan_1003|M.vanbaalenii_PYR-1 SSLVAVHQACQALRLAECDVALAGGVNVLLSPATMINFSRARMLAPDGRC
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK KTFDAAADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASG
MAB_0939|M.abscessus_ATCC_1997 KTFDAAADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASG
MSMEG_0408|M.smegmatis_MC2_155 KTFDAAADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASG
Mvan_1003|M.vanbaalenii_PYR-1 KTFDATADGYVRGEGCGVVVVKRLADAIRHGDRIRAVIRGSAVNQDGASG
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GLTVPNGVAQQRVIGDALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAG
MAB_0939|M.abscessus_ATCC_1997 GLTVPNGVAQQRVIADALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAG
MSMEG_0408|M.smegmatis_MC2_155 GLTVPNGVAQQRVIADALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAG
Mvan_1003|M.vanbaalenii_PYR-1 GLTVPNGAAQQRVIADALTNAGLTAADVDYLEAHGTGTPLGDPIEVQAAG
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AALGPGREPQRPLLIGSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHL
MAB_0939|M.abscessus_ATCC_1997 AAYGIGRETNDPLLIGSAKTNIGHLEAAAGIAGVIKVILSLENELLPQHR
MSMEG_0408|M.smegmatis_MC2_155 EVLGAGRAPEEPLLIGSAKTNIGHLEAAAGIAGVIKVVMALENETLPKHL
Mvan_1003|M.vanbaalenii_PYR-1 AVLGVGREPDRPLLIGSVKTNIGHLEAASGIAGLLKVILSLEHQVLPKHL
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK NFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPRIAGVSSFGFAGTNAH
MAB_0939|M.abscessus_ATCC_1997 NFQNPSPHIPWDRLPVEVVREARPWGR---NGRPRIAGVSSFGFAGTNAH
MSMEG_0408|M.smegmatis_MC2_155 NFETPSPHIPWERLPIEVVRETVPWQR---NGKPRIAGVSSFGFAGTNAH
Mvan_1003|M.vanbaalenii_PYR-1 NFRSPSPHIPWNRLPVRIVDDPVPWTR---SGRSRVAGISSFGFSGTNAH
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VILEEAPLAAEPAQES---VDDGRFTLLPLSARTPAALMAVADRYRDWLV
MAB_0939|M.abscessus_ATCC_1997 VILEEAPVVSRDAVEPPAPAGGRKFSILPLSARTPAALAQLADKYRAWLN
MSMEG_0408|M.smegmatis_MC2_155 VILEEAPAVGTPATTEP-VEDPRRYSVLPLSARTPEALVRLAGEYRDWLR
Mvan_1003|M.vanbaalenii_PYR-1 VLVEEAPRADRAGAAPQ-PAAPGGFGMLPLSARTPDALAATAHRLRTWLA
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ANPDATLADLCFTAGTARSHLEHRAALVVNTREAALDLLGALADDRPAPG
MAB_0939|M.abscessus_ATCC_1997 AHPEAALADLCFTAGVGRAHLEHRAALVVNTREAAVELLSAVADDRPAPG
MSMEG_0408|M.smegmatis_MC2_155 AHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPG
Mvan_1003|M.vanbaalenii_PYR-1 ANPDASWPDLCFTAAVGRSHLRHRAALVVDSRSSVEELLGALAEDRPGPG
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LVRGESHDTPKTAWLFTGQGSQYPGMSRELFDTEPLFAETLRECAAAVDG
MAB_0939|M.abscessus_ATCC_1997 LGRGESHDTPKTAWLFTGQGSQYPGMARELFETEPVFADTLNRCAAAVAD
MSMEG_0408|M.smegmatis_MC2_155 LVRGESHEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVAD
Mvan_1003|M.vanbaalenii_PYR-1 LARGECGDPPKTAWLFTGQGSQYPGMGRELFDTEPVYREVMTRCAEAVAD
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK MLEKPLLDVIFDTDGVLDTDSNETLRHTSYAQPALFAVEMGLARLWQSWG
MAB_0939|M.abscessus_ATCC_1997 VLEKPLLDVIFDVD---GPEAEETLRQTSYAQPALFAVEMGLARLWQSWG
MSMEG_0408|M.smegmatis_MC2_155 ILEKPLLDVIFDAD-ELDGDTESPLRHTTYAQPALFAVELGLARLWQSWG
Mvan_1003|M.vanbaalenii_PYR-1 VLERPLLDVVFDAD------GGEALRHTSYAQPALYAVEMGLARLWQSWG
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK FEPDVVLGHSVGQYAAACVAGVLSLRDGARLMAERGRLFGSLPSGGRMAA
MAB_0939|M.abscessus_ATCC_1997 FEPDVVLGHSVGQYSAACVAEVFSLEDGARLIAERGRLFSSLPAGGRMAA
MSMEG_0408|M.smegmatis_MC2_155 FEPDVVVGHSVGQYSAACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAA
Mvan_1003|M.vanbaalenii_PYR-1 IEPDVVLGHSVGQYAAACVAGVMGLEDGAVLLAERGRLFGSLPEGGRMAA
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK VFAAAERVEALTDEYPALSVAAYNGANTVLSGPATDLERAVAGLVADGVR
MAB_0939|M.abscessus_ATCC_1997 VFTDAERAERLTDEFPSLSVAAYNGANTVLSGPAQDLEKAIAALVADGVR
MSMEG_0408|M.smegmatis_MC2_155 VFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESAVATLVADGVR
Mvan_1003|M.vanbaalenii_PYR-1 VFAPADRVESCTVDSPLLSVAAYNGDNTVLSGPAGDLERAVAGFSAAGVR
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu ---------------------------------LLSLLRQRSERYGDKIA
Mflv_0405|M.gilvum_PYR-GCK CDWLETSHAFHSALLDPILDDFESYARGITFTAPQRILIDNRTGAALGRS
MAB_0939|M.abscessus_ATCC_1997 CDFLETSHAFHSALLDPILDEFEAYANQFNYKTPQRILIDNRTGTALGRS
MSMEG_0408|M.smegmatis_MC2_155 CDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRS
Mvan_1003|M.vanbaalenii_PYR-1 CDWLDTSHAFHSALLDPVLEEFESCADRFEFGTPQRTLVCNRSGEVLSRH
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu FDYCTGEQEHSRLTYQELDIRARAIAAHLQDQGVAGERVLVLCPSGLDFI
Mflv_0405|M.gilvum_PYR-GCK VTLDAAYWRRHARQPVEFAKSVHTLADMNCKLLVEIGPRPVLTAAALSAW
MAB_0939|M.abscessus_ATCC_1997 VKLDGAYWRRHARQPVEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAW
MSMEG_0408|M.smegmatis_MC2_155 TRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAW
Mvan_1003|M.vanbaalenii_PYR-1 ARLDGQYWRRHARQPVRFAESVRTLADLGCRLLMEIGPQPVLTAAAMRTW
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu TAMFGCFYVGAVAVPVHPPVHNRLLSRVASIVADVRATSVLTTAATRADL
Mflv_0405|M.gilvum_PYR-GCK PDPATSPRVIASLRRTTADQRQITEAVADAYVLGHLPRFAAFRRDGARVL
MAB_0939|M.abscessus_ATCC_1997 PDPATAPRAIASLRRNTADHRQITEAAADAYVLGHLPDFGAFQHAPARKL
MSMEG_0408|M.smegmatis_MC2_155 PDPATTPQVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKL
Mvan_1003|M.vanbaalenii_PYR-1 PGTVTAPRVAASMRRKGSDRRQITEALAQAYVAGHRPETAARQHGRGRLL
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu KEILDGLHDGDPLRWLAVDTIEADDETSWTPTTVDTDSVAFVQYTSGSTS
Mflv_0405|M.gilvum_PYR-GCK DLPTYPFEHRQYWFSDSRE---PVAAAPQR---GARTETVRLLEDGRIEE
MAB_0939|M.abscessus_ATCC_1997 DLPTYPFERRQYWFSDKRDGDNRDAGNRQQNNGGPRTEAVRLLEDGKIEE
MSMEG_0408|M.smegmatis_MC2_155 DLPTYPFEHRQFWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEE
Mvan_1003|M.vanbaalenii_PYR-1 DLPTYPFQHRAYWFP--------QGQARTAPTDPVHTETVRFLDEERIDE
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu TPKGVVLTHHN-----------LLANLESISRDAGQGDEARVVSWLPLHH
Mflv_0405|M.gilvum_PYR-GCK LAALLGGTVDDPFTFDVLNRLAAQHNQQRSTESIADDRYQIRWETAAEPP
MAB_0939|M.abscessus_ATCC_1997 LANLLGGVDGDQQTLNVLTKLAAQHNLQRTTQTIADDRYQFRWEKSPTPL
MSMEG_0408|M.smegmatis_MC2_155 LAALIDGETVDEQTLRVLNKLAARHNQQRSTHVDPDARYEIRWDAIASAA
Mvan_1003|M.vanbaalenii_PYR-1 LAALLDGPTGSAQTVDVLSKLAARHRQQRGAQSIADARYQIRWEKSEAPG
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu DMGLIGGIFGVVHFGGTAYLMPPSSFIQRP----------MSWLEAISWH
Mflv_0405|M.gilvum_PYR-GCK VGADAADGITWLLVGDDTDATRPLVDVLAARGHRYRILGLPKSGAEEHEL
MAB_0939|M.abscessus_ATCC_1997 SGSQAAGGVTWLLVADAAGAAQPLLDVLTARGQQHRVLALPVSDADEAEL
MSMEG_0408|M.smegmatis_MC2_155 ASTGAAA--DWILVGDDTAAVLEFADALTAGGHRHQIVALPGSDADEAQL
Mvan_1003|M.vanbaalenii_PYR-1 AARPTTEATTWLLVTHDSRAAQPIAEVLERRGHPYHIVGLPGSDADAAPA
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu GANISVGPNFGYQLCVERSTPEERATLDLSTWVRAYCGAEPVRAATMRRF
Mflv_0405|M.gilvum_PYR-GCK ADTLRDAAADATDLRIVHVAALDAAESDTSMKSLLRMQHRVLGGTRRLFG
MAB_0939|M.abscessus_ATCC_1997 VEALRSAADEDSALRIVHVAALAGQGS-SSAQSLLRIQHQVLGGTRRLFR
MSMEG_0408|M.smegmatis_MC2_155 VDTLRAASAG--ELYVVHIAAGDGAAA--PMRDLLRVQHRTLGGLRRLFR
Mvan_1003|M.vanbaalenii_PYR-1 EEALRATVSQ-PRPHILYLAALEEPGG-SAAETLGWMQHRVLAAARRLFQ
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu TEAFAPAGFRADAFHPVYGLAEATLFVSGRPENVLPTVRSLDNAALREHR
Mflv_0405|M.gilvum_PYR-GCK AAVAAQLRSPMWLVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWG
MAB_0939|M.abscessus_ATCC_1997 AAAAAELRAPIWIVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWG
MSMEG_0408|M.smegmatis_MC2_155 AANDAELRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWG
Mvan_1003|M.vanbaalenii_PYR-1 LAATAGARAPIWLITAGAQRITGDETVEPAQTSLWGFGRAAALEQPELWG
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu VVPAAADDANAAAVVGCGPAAYGEEIVIVDPATRREFPPDVVGEIWVAGE
Mflv_0405|M.gilvum_PYR-GCK GLADLGGGTSDEWSRLLNRIAATHDPAVMEDQVAVRGSTSYVPRLVHRDT
MAB_0939|M.abscessus_ATCC_1997 GLADLSDAGTDEWAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREE
MSMEG_0408|M.smegmatis_MC2_155 GLADLSGADT-EWPRLIARITSPRDG---EDQIALRGDAVYAPRLVRRTG
Mvan_1003|M.vanbaalenii_PYR-1 GLADVTTGDAEEWSALIDHIVAAPTS---EDQIAVRGREIHVARLTRCAE
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu NVAQG---------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LPSGKPLHLRADATYLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDE
MAB_0939|M.abscessus_ATCC_1997 LPSGKPLEVRSDATYLVTGGLGSIGLEIAGYLAGRGAKHLVLTSRREPGE
MSMEG_0408|M.smegmatis_MC2_155 EPSDTPLPVREDRTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPGD
Mvan_1003|M.vanbaalenii_PYR-1 KANAAALELRREATYLVTGGLGALGLEVAEFLASHGAGHLVLTGRRSASD
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu -------YLGKPSESAETFAAHLADSGRGPFLRTGDYGFLLDGELFVTGR
Mflv_0405|M.gilvum_PYR-GCK AAASRIEALRERHGCEVRVVTADVADAHAVARLLATVQAEMPPLAGIVHA
MAB_0939|M.abscessus_ATCC_1997 AARQRIDALAA-QGCEVRAVTADVADGHDVARLLAGIQAELPPLAGIVHA
MSMEG_0408|M.smegmatis_MC2_155 DARRRLDGLREQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHA
Mvan_1003|M.vanbaalenii_PYR-1 TVRQRIDAMRERFDCQVLVATADVADRDDVARLFSTMRSELPPLAGIVHA
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu LKDLIIIRGRNYHPNDIEATVQEVHPALMSGRGAAFAVSPDPSGTEQLVI
Mflv_0405|M.gilvum_PYR-GCK AGEIGTTPLADLDDAEVDRVFAGKVWGAWHLSEATSDLQ--LDFFISTSS
MAB_0939|M.abscessus_ATCC_1997 AGEIGTTPLSDLEDAEVDRVFAGKVWGAWHLSEAAAGLK--LDFFINTSS
MSMEG_0408|M.smegmatis_MC2_155 AGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSS
Mvan_1003|M.vanbaalenii_PYR-1 AGEIGTSPLRTLDDAEMDRVFAGKVWGAVYLCEEVADMG--LDFFLATSS
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu VQEVDRGRLGEVDTDELIAAIRTAVTSQHDIGVHTVVLVDPLRIPTTSSG
Mflv_0405|M.gilvum_PYR-GCK IASVWGGFGQAAYGAANAFLDGLAWRLREQGVAGVSVNFGPWSAGMADAQ
MAB_0939|M.abscessus_ATCC_1997 IAAVWGGYGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAE
MSMEG_0408|M.smegmatis_MC2_155 IASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAE
Mvan_1003|M.vanbaalenii_PYR-1 IASVWGSHGQTAYGAANAFLDGLADSLRARGIPGISVNFGPWAAGMADAK
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu KIRRRTCRQRFLDGELDAFAEWRLATPRPAQPVPAADEQADEQAGAGPGA
Mflv_0405|M.gilvum_PYR-GCK SRARLEQRGIKTLSPADALAGLSDAVISAAP---HPVVARVDWSRFLPLY
MAB_0939|M.abscessus_ATCC_1997 SRARLEQRGIKTLSPTDALAGLADVVAASGSNAVQGVIARIDWARFLPLY
MSMEG_0408|M.smegmatis_MC2_155 SRARLEQRGVRTLSPAEALAGMADVVAGPVQ----GVVAKIDWSRFLPLY
Mvan_1003|M.vanbaalenii_PYR-1 AREQLSRRGVKTLAPADALAGMADVIAASTA---HAVVARIDWATFLPVY
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
TH_4458|M.thermoresistible__bu GPGADEIRAWFVAQLAGELG------------------------------
Mflv_0405|M.gilvum_PYR-GCK QQAGRRGFLAELERELPAAPAQQGPAVTASGRTPLVERLTTAPLQQRKRL
MAB_0939|M.abscessus_ATCC_1997 QQAGKRGFLAELDREVPSHLA--GVAGAQSGSTQLVERLANAPVQQRKKL
MSMEG_0408|M.smegmatis_MC2_155 QQAGRRAFLSELESELPAAATGAAAPATVPGKPPLVEQLTKAPVQQRKSL
Mvan_1003|M.vanbaalenii_PYR-1 QLQRRRAFLSQLEREVPDVPD--ASAPAPSGTTRFVEELTLAPVEQRRKL
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 ------------------------------------MTASVEGADQKSEK
TH_4458|M.thermoresistible__bu ----------------------LSPDDIDTGQPFAYYGLDSVRAIQLMTA
Mflv_0405|M.gilvum_PYR-GCK LTDYLRDAVAEVTRVDAAEIREDAGFFDLGMDSLMAVELRRRIETGVGKE
MAB_0939|M.abscessus_ATCC_1997 LTDYLRDAVAEVTRVDVSEIREDAGFFDLGMDSLMAVELRRRMEQGVGKE
MSMEG_0408|M.smegmatis_MC2_155 ITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKD
Mvan_1003|M.vanbaalenii_PYR-1 VLEYLRAAVAEVTRVDAAEIRDEAGFFDLGMDSLMAIELRRRLEQGLGKE
MMAR_2473|M.marinum_M --------MSRAT------------------------SLRRQHGDGD---
MUL_1655|M.ulcerans_Agy99 -------MMSRAT------------------------SLRRQHGDGD---
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 LISYLKKVVVELD------------------------ETRARLREYE---
TH_4458|M.thermoresistible__bu LEAWSGIKVAPTLAYDHPTIDLAAEHLAGLTHTATSTAADAGVSTGAGRR
Mflv_0405|M.gilvum_PYR-GCK IPVTLVMDHPRLSDAADYLLGDVLGLTEAAT-APKAATVVSTAADEPIAI
MAB_0939|M.abscessus_ATCC_1997 IPVTLVMDHPRISDVADYLLGDVLGLAEQAKPAAQLASAVTGRTDEPIAI
MSMEG_0408|M.smegmatis_MC2_155 IPVTLVMDHPRLSDAADYLLVEVLGLGEQTN--VRQASTVTARTDDPIAV
Mvan_1003|M.vanbaalenii_PYR-1 LPVTLAMDHPHLSDAAEYVLGDVLGLSEHTV--AQPDTPSTVRTDDPIAI
MMAR_2473|M.marinum_M -----------------------------------------QEFASAVAI
MUL_1655|M.ulcerans_Agy99 -----------------------------------------QEFASAVAI
Mb1692|M.bovis_AF2122/97 ------------------------------------------MQPTGIAI
Rv1664|M.tuberculosis_H37Rv ------------------------------------------MQPTGIAI
MAV_3107|M.avium_104 ------------------------------------------MPPTDVAI
MLBr_00135|M.leprae_Br4923 -----------------------------------------QRATEPVAV
TH_4458|M.thermoresistible__bu PEHG----------------------------------PAPDRADEPIAI
:*:
Mflv_0405|M.gilvum_PYR-GCK VAVSCRFPG-APNPEAFWDLLSGGVDAIREVPEDR-FDIDEFYDPDPDAA
MAB_0939|M.abscessus_ATCC_1997 VAVSCRFPG-APDPEAFWDVLSGGVDAIREVPEDR-FDIDEFYDPDPEVA
MSMEG_0408|M.smegmatis_MC2_155 VAVSCRFPG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTP
Mvan_1003|M.vanbaalenii_PYR-1 VGMACRFPG-ADDTDAFWSVLAEGADLIREIPDDR-FDINEFYDPDPEAA
MMAR_2473|M.marinum_M IGVACRFPG-AANPGEFWELVSEGHEVA----------------------
MUL_1655|M.ulcerans_Agy99 IGVACRIPG-AANPGEFWELVSEGHEVA----------------------
Mb1692|M.bovis_AF2122/97 IGLACRFPT-VVSPGDLWDLLRDGREAT----------------------
Rv1664|M.tuberculosis_H37Rv IGLACRFPT-VVSPGDLWDLLRDGREAA----------------------
MAV_3107|M.avium_104 IGMACRFPG-APDPGSFWRLLRDGREVT----------------------
MLBr_00135|M.leprae_Br4923 VGIGCRFPGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAE
TH_4458|M.thermoresistible__bu IGIGCRFPG-ADGPAAYWRLLREGRDAITATPPER----------WDTDS
:.:.**:* . .. * :: :
Mflv_0405|M.gilvum_PYR-GCK GKTYTRYGGFLDHIDEFDPEFFGLSPREAVWIEPQQRLMLETVWEGLERA
MAB_0939|M.abscessus_ATCC_1997 GKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERA
MSMEG_0408|M.smegmatis_MC2_155 GKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERA
Mvan_1003|M.vanbaalenii_PYR-1 GKIYSRYGGFLDGVDGFDPEFFGISPREAVWIDPQQRLVLETAWEGLERA
MMAR_2473|M.marinum_M --------KPIDHVGDFDAEFFNVSPREAAAMDPRQRLALELAWELFEDA
MUL_1655|M.ulcerans_Agy99 --------KPIDHVGDFDAEFFNVSPREATAMDPRQRLALELAWELFEDA
Mb1692|M.bovis_AF2122/97 --------GSIDNVADFDADFFNLSPREASAMDPRQRLALELTWELLEDA
Rv1664|M.tuberculosis_H37Rv --------GSIDNVADFDADFFNLSPREASAMDPRQRLALELTWELLEDA
MAV_3107|M.avium_104 --------RFAGEAAEFDADFFNLSPREAAAMDPRQRLALELAWELLEDA
MLBr_00135|M.leprae_Br4923 GKTYTRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYA
TH_4458|M.thermoresistible__bu VGDGTRWGGFLERIDGFDAGFFGISPREAVRIDPQQRLLLEVAWEALEDA
**. **.::* *. ::*:*** ** ** :* *
Mflv_0405|M.gilvum_PYR-GCK GYAPSALRGSRTGVFVGVAANEYAHLLSAESIDKIEPHFITGNALNAISG
MAB_0939|M.abscessus_ATCC_1997 GYSPAALRGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISG
MSMEG_0408|M.smegmatis_MC2_155 GYAPSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISG
Mvan_1003|M.vanbaalenii_PYR-1 GYSAAALRGSRSGVYVGVGANEYSHLLSGGSLDGIEAQFITGNALNVIAG
MMAR_2473|M.marinum_M RIVAESVRGEPIAVYLGAMNDDYALLTLDQAPDKLDHYSFAGASRGMIAN
MUL_1655|M.ulcerans_Agy99 RIVAESVRGEPIAVYLGAMNDDYALLTLDQAPDKLDHYSFAGASRGMIAN
Mb1692|M.bovis_AF2122/97 FVVPETLRGQPIAVYLGAMNDDYAVLTL--AADRVDHHAFAGTSRAIIAN
Rv1664|M.tuberculosis_H37Rv FVVPETLRGQPIAVYLGAMNDDYAVLTL--AADRVDHHAFAGTSRAIIAN
MAV_3107|M.avium_104 FIVAETLRGEAVSVYLGAMTDDYAALTLRDVPDNVDHHTFTGVSRGMIAN
MLBr_00135|M.leprae_Br4923 GIDPLSLRGSATGVFTGIFAPSYGSRDT----GGLQGYGLTGTAVSVASG
TH_4458|M.thermoresistible__bu GLVPDRLAGSRTGVFTGVSTYDYLHLQLS-HPELIDAYSGTGTASSIAAN
. : *. .:: * .* :: :* : :.
Mflv_0405|M.gilvum_PYR-GCK RVAFALGLEGPAVAVDTACSSSLVAVHQATQALR-SGDCDMALAGGVNVL
MAB_0939|M.abscessus_ATCC_1997 RVAFALGFEGPAVAVDTACSSALVAVHQAVQALH-SGDCDLALAGGVNVL
MSMEG_0408|M.smegmatis_MC2_155 RVAFALGFEGPAVAVDTACSSALVAVHQACQALQ-SGDCDLALAGGVNVL
Mvan_1003|M.vanbaalenii_PYR-1 RVSFTLGLEGPAVAVDTACSSSLVAVHQACQGLQ-SGDCDLALAGGVNVL
MMAR_2473|M.marinum_M RVSYGFALHGPSMTVDCGQSSSLVAVHLAREYLRGAGDATMAIAGGIHLN
MUL_1655|M.ulcerans_Agy99 RVSSGFALHGPSMTVDCGQSSSLVAVHLAPGYLRGAGDATMAIAGGIHLN
Mb1692|M.bovis_AF2122/97 RVSFAFGLRGPSVTIDSGQSSSLVAVHLACESVR-TGEAPLAIAGGVHLN
Rv1664|M.tuberculosis_H37Rv RVSFAFGLRGPSVTIDSGQSSSLVAVHLACESVR-TGEAPLAIAGGVHLN
MAV_3107|M.avium_104 RISYLLGLRGASMTVDSGQSSSLVAVHLGCESVR-SGQAPLAIAGGVHLN
MLBr_00135|M.leprae_Br4923 RVSYVLGLEGPAVSVDTACSSSLVAIHWAMSSLR-SGECDLALAGGVTVM
TH_4458|M.thermoresistible__bu RLSYVFDFRGPSLTLDSACSSSLVAVHQACRSLR-DGECDLALAGGVNIM
*:: : :.*.::::* . **:***:* . :: *:. :*:***: :
Mflv_0405|M.gilvum_PYR-GCK LSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVR
MAB_0939|M.abscessus_ATCC_1997 LSPVTVIAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAER
MSMEG_0408|M.smegmatis_MC2_155 LSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVR
Mvan_1003|M.vanbaalenii_PYR-1 LSPATTIATSRARMLSPDGRCKTFDAAADGYVRGEGCGILVLKRLSDAVR
MMAR_2473|M.marinum_M LASETGRLETEFGAVSASGRTYAFDARADGYVRSEGGGLVLLKPLRAALE
MUL_1655|M.ulcerans_Agy99 LASETGRLETEFGAVSASGRTYAFDARADGYVRSEGGGLVLLKPLRAALE
Mb1692|M.bovis_AF2122/97 LARETAMLEQEFGAVSPSGHTYAFDERADGYVPGDGGGLVLLKPVQAALD
Rv1664|M.tuberculosis_H37Rv LARETAMLEQEFGAVSPSGHTYAFDERADGYVPGDGGGLVLLKPVQAALD
MAV_3107|M.avium_104 LADEIALLEREFGAVSVSGHTYAFDRRADGYVRGEGGGLVLLKPLAAARR
MLBr_00135|M.leprae_Br4923 GLPSIFVGFSRQRGLAADGRCKAFARAADGTGWGEGAGVVVLERLSDAQR
TH_4458|M.thermoresistible__bu LSAGIGLNFTRAGVMATDGRCKTFDARADGWVRGEGAGIVVLKPLREALA
. :: *: :* *** .:* *:::*: : *
Mflv_0405|M.gilvum_PYR-GCK DGDRVCAVIAGSAVNQDGASS-GLTVPNGGAQQRLIGTVLARAGITGGEV
MAB_0939|M.abscessus_ATCC_1997 DGDRVLAVIPGSAVNQDGASS-GLTVPNGGAQQRLIGSVLARAGLVGGDV
MSMEG_0408|M.smegmatis_MC2_155 DGDRVCAVIPASSVNQDGASS-GLTVPNGGAQQRLIEATLARAGLSGADV
Mvan_1003|M.vanbaalenii_PYR-1 DGDRIQAVIRGSAVNQDGASG-GLTVPNGGAQQRVIAAALTRAGLSGSDI
MMAR_2473|M.marinum_M DGNRIRAVILGAAVGSAGHTAGGLAAPSAAAEADVMRRAMASAGVDPNQI
MUL_1655|M.ulcerans_Agy99 DGNSIRAVILGEAVGSAGHTAGGLAAPSAAAEADVMRRAMASAGVDPNQI
Mb1692|M.bovis_AF2122/97 DGDRIHAIIRGSAVGNAGHSATGLTVPSVAGQVDVIRRAMSGAGVDCHQV
Rv1664|M.tuberculosis_H37Rv DGDRIHAIIRGSAVGNAGHSATGLTVPSVAGQVDVIRRAMSGAGVDCHQV
MAV_3107|M.avium_104 DGDRIHAVIRATAVGNAGHGAPAQTLPSAAAEADVIGRALAEAGLGGADI
MLBr_00135|M.leprae_Br4923 LGHTVLAVVRGSAVNQDGASN-GLTAPNGLAQQRVIQAALTNAGLSSADV
TH_4458|M.thermoresistible__bu DEDPIYAVIRGSAVNQDGRTN-GLMAPSRTAQEVVLTDAYRRAGVSPGVV
. : *:: . :*.. * . *. .: :: . **: :
Mflv_0405|M.gilvum_PYR-GCK DYLEAHGTGTPLGDPIEVQAAAAAYAGARDADRPLLMGSVKTNIGHTESA
MAB_0939|M.abscessus_ATCC_1997 DYLEAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMGSVKSNIGHTESA
MSMEG_0408|M.smegmatis_MC2_155 DYLEAHGTGTPLGDPIEVQAAAAAYGAGRDADRPLLMGSVKTNIGHTESA
Mvan_1003|M.vanbaalenii_PYR-1 DYLEAHGTGTSLGDPIEVQAAGAVLGAGRDPDRPLLMGSVKTNVGHLESA
MMAR_2473|M.marinum_M DYIEAHGTGTRIGDTTEAQALSEVFATR---ETPVWLGSVKSNIGHTGAA
MUL_1655|M.ulcerans_Agy99 DYIEAHGTGTRIGDTTEAQALSEVFATR---ETPVWLGSVKSNIGHTGAA
Mb1692|M.bovis_AF2122/97 HYVEAHGTGTKIGDPIEARALGEIFAARQ--RRPVSVGSVKTNIGHTGGA
Rv1664|M.tuberculosis_H37Rv HYVEAHGTGTKIGDPIEARALGEIFAARQ--RRPVSVGSVKTNIGHTGGA
MAV_3107|M.avium_104 DYVEAHGTGTRVGDAVETQALGRIFAERS--HHPVSVGSVKTNIGHAASA
MLBr_00135|M.leprae_Br4923 DVVEAHGTATTLGDPIEAQALLATYGQGRPADQPLWVGSIKSNMGHTQAA
TH_4458|M.thermoresistible__bu QYVEAQGIGTPVGDAIEVGALGTVLAEDRPPDSPCLIGSVKTNIGHLEAA
. :**:* .* :**. *. * . * :**:*:*:** .*
Mflv_0405|M.gilvum_PYR-GCK SGAAGLIKVVLSLQHETLPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQPN
MAB_0939|M.abscessus_ATCC_1997 SGAAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQAN
MSMEG_0408|M.smegmatis_MC2_155 SGAAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTN
Mvan_1003|M.vanbaalenii_PYR-1 SGVAGLIKVVLSLQHEMLPRHLHFKTPSPHIPWDRLAVRVVAEPTPWRAD
MMAR_2473|M.marinum_M AGAAGLIKTVLSLENGAIPASLNYVGDSAGTDMESHGLHVSTTLTPWPRG
MUL_1655|M.ulcerans_Agy99 AGAAGLIKTVLSLENGAIPASLNFVGDSAGTDMESHGLHVSTTLTPWPRG
Mb1692|M.bovis_AF2122/97 AGIAGLLKAVLAIENAVIPPSLNYVG--APIDLDSLGLRVDTALTPWPVA
Rv1664|M.tuberculosis_H37Rv AGIAGLLKAVLAIENAVIPPSLNYVG--AAIDLDSLGLRVDTALTPWPVA
MAV_3107|M.avium_104 AGIAGLLKAVLAIEHAAIPPNLHFERPDPDIDLNRLGLRVNTALAPWPDR
MLBr_00135|M.leprae_Br4923 AGVAGVIKMVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDWSVE
TH_4458|M.thermoresistible__bu AGIAGLIKVALALRHRMIPPTLNFTEPNPTIEFDKLPVRVAQTLTPWPDD
:* **::* . ::.: :* *: . : * *
Mflv_0405|M.gilvum_PYR-GCK GRPRRAGVSSFGFTGTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADP
MAB_0939|M.abscessus_ATCC_1997 GRPRRAGVSSFGFTGTNAHVLIEEAPQPQATP----------DEDDASTP
MSMEG_0408|M.smegmatis_MC2_155 GRVRRAGVSSFGFTGTNAHVLVEEAPPQLHTADAAP----VEPAATAEAG
Mvan_1003|M.vanbaalenii_PYR-1 GRPRRAGVSSFGFSGTNAHVVLEEPPAQSADLRQPPTDGKDGAAGLESAT
MMAR_2473|M.marinum_M AGPRRAGVSSFGMGGTNAHVIVQQAPIP--------------QEAVADPD
MUL_1655|M.ulcerans_Agy99 AGPRRAGVSSFGMGGTNAHVIVQQAPIP--------------QEAVADPD
Mb1692|M.bovis_AF2122/97 DEPRRAGVSSFGMGGTNAHVILEQGPTQSPEI---------VESVAAAGS
Rv1664|M.tuberculosis_H37Rv DEPRRAGVSSFGMGGTNAHVILEQGPTQSPEI---------VESVAAAGS
MAV_3107|M.avium_104 GGPRRAGVSSFGMGGTNAHVIVEQDAAQ--------------QNPTPASA
MLBr_00135|M.leprae_Br4923 GRPRRAGVSSFGISGTNAHVILEEAPTP---V---------EASYSTADQ
TH_4458|M.thermoresistible__bu SGRAVAGVSAFGFGGTNAHVVLAEAPQVR-------------AAATADDH
****:**: ******:: : .
Mflv_0405|M.gilvum_PYR-GCK APAPVEVLPLSARSPEALVALAQRYETWLTAHPEADLADVCRTAGTGRSH
MAB_0939|M.abscessus_ATCC_1997 QSAPVSVLPLSARSPEALAAVAQRYESWLAAHPDVDLEDVCLTAGRGRSH
MSMEG_0408|M.smegmatis_MC2_155 TDDSPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSH
Mvan_1003|M.vanbaalenii_PYR-1 APEPAGVLPISARSPEALTALARRYESWLTAHPDADIADVCYTAGAGRSH
MMAR_2473|M.marinum_M GTEATVPWLVSARSRAALAGQAQRLAAWVAELPSIDVADVGWSLLSTRSV
MUL_1655|M.ulcerans_Agy99 GTEATVPWLVSARSRAALAGQAQRLAAWVAELPSIDVADVGWSLLSTRSV
Mb1692|M.bovis_AF2122/97 NAPVAVPWVLAARSPQALTNQAGRLLAHLTADDGLTALDVGWSLVSTRSV
Rv1664|M.tuberculosis_H37Rv NAPVAVPWVLAARSPQALTNQAGRLLAHLTADDGLTALDVGWSLVSTRSV
MAV_3107|M.avium_104 PADVALPWVLSARSERALALQAQRLSAHLAERPQASPLDVGWSLVSARAV
MLBr_00135|M.leprae_Br4923 QRLSVVPWVVSGRSTAALMAQASRLAFYVQADPEVDPVDVGCALA-ARSV
TH_4458|M.thermoresistible__bu ADGFVEILPLSARSQAALDALAERYESALTG--GVPPADLCHTAGARRAH
::.** ** * * : *: : *:
Mflv_0405|M.gilvum_PYR-GCK FEHRAALVVDSVESARIALTDLAQNRLRPGVVRG--EHLNHPTTAWMFTG
MAB_0939|M.abscessus_ATCC_1997 FEHRAALVVDSIQTAREGLLELAQNRLRPGVVRG--EHTNHPTTAWLFTG
MSMEG_0408|M.smegmatis_MC2_155 FEYRAALVVDSVERAREGLAALAEGRTPAGVVRG--EHVHRPTTAWLFTG
Mvan_1003|M.vanbaalenii_PYR-1 FEHRAALVVDSVDGARDLLAGLAEDRLGPGAVRG--VCGDPPKTAWLFTG
MMAR_2473|M.marinum_M FEHRAVLVGGDRGGFMAGLAALASGEPGVNLVAG--RAGSGGKTVLVFPG
MUL_1655|M.ulcerans_Agy99 FEHRAVLVGGDRGGFMAGLAALASGEPGVNLVAG--RAGSGGKTVLVFPG
Mb1692|M.bovis_AF2122/97 FDHRAVVVGADRGRLMAGLAGLAAGEPGAGVVVG--RARSVGKTVFVFPG
Rv1664|M.tuberculosis_H37Rv FDHRAVVVGADRGRLMAGLAGLAAGEPGAGVVVG--RARSVGKTVFVFPG
MAV_3107|M.avium_104 FEHRAVLVGCERGVLATGLAGVASGRPDAATVVG--RARATGKTVLVFPG
MLBr_00135|M.leprae_Br4923 FEHRAVVVGESREQLIAGLAGLAVGESGAGVAIG--QAAPLGKTVVVFPG
TH_4458|M.thermoresistible__bu HDHRLAVVGASRAELIGALAAYRRGEPHPGVFTGRSQSGHRSGVVFVFSD
.::* .:* . * .. * .. :*..
Mflv_0405|M.gilvum_PYR-GCK QGSQYPGMARELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAG
MAB_0939|M.abscessus_ATCC_1997 QGSQYPGMARELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETG
MSMEG_0408|M.smegmatis_MC2_155 QGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET-
Mvan_1003|M.vanbaalenii_PYR-1 QGSQYPGMARELFDTEPVFRDTVTRCAEAIGDTLPRPLLEVLFDTDGDN-
MMAR_2473|M.marinum_M QGAQWLGMGRDLYGRFPAFAKAFDTVADALDEHLRLPLREVIWGADASL-
MUL_1655|M.ulcerans_Agy99 QGAQWLGMGRDLYGRFPAFAKAFDTVADALDEHLRLPLREVIWGADASL-
Mb1692|M.bovis_AF2122/97 QGSQWLGMGRQLYGRYSVFARAFDEVVAVLDGQLRLSVRQVMWGADAGL-
Rv1664|M.tuberculosis_H37Rv QGSQWLGMGRQLYGRYSVFARAFDEVVAVLDGQLRLSVRQVMWGADAGL-
MAV_3107|M.avium_104 QGSQTLGMGRQLYERFVVFARALDEAVAVVDEHSRLSVREVMWGADPEL-
MLBr_00135|M.leprae_Br4923 QGAQRIGMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGADAGL-
TH_4458|M.thermoresistible__bu EGSQWRGMAQRLYAEDQVFRTALAECDRALRRHMEISPLSELLADPSHSR
:*:* **.: * .* . : . . :
Mflv_0405|M.gilvum_PYR-GCK VPPTETLRHTSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAAC
MAB_0939|M.abscessus_ATCC_1997 GKAGEALRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAAC
MSMEG_0408|M.smegmatis_MC2_155 ---ADLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAAC
Mvan_1003|M.vanbaalenii_PYR-1 ---GQTLRHTSYAQPALFAIEMGLARLWQARGIEPDVVLGHSVGQYAAAC
MMAR_2473|M.marinum_M ------LEGTEFAQPALFALEVALAALLQACGVVADLVMGHSVGEISAAH
MUL_1655|M.ulcerans_Agy99 ------LEGTEFAQPALFALEVALAALLQACGVVADLVMGHSVGEISAAH
Mb1692|M.bovis_AF2122/97 ------LESTEFAQPALFVVQVALAALLQDWGVLPDLVMGHSVGEIAAAY
Rv1664|M.tuberculosis_H37Rv ------LESTEFAQPALFVVQVALAALLQDWGVLPDLVMGHSVGEIAAAY
MAV_3107|M.avium_104 ------LQSTEFAQPALFVFEVALAALWESLGVTPDVVMGHSVGEIAAAC
MLBr_00135|M.leprae_Br4923 ------LDSTEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAY
TH_4458|M.thermoresistible__bu ------MDEVTIASPALFAVQVALAALWQSWGVEPAAVIGHRMGEVAAAH
: . *.****..::.* : : .: . *:** :*: :**
Mflv_0405|M.gilvum_PYR-GCK VAGVFSLEDGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAADFPRV
MAB_0939|M.abscessus_ATCC_1997 VAGVFSIEDGARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPRV
MSMEG_0408|M.smegmatis_MC2_155 VAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRV
Mvan_1003|M.vanbaalenii_PYR-1 VAGVFGLEDGARLVADRGRLFGGLPVGGRMVAVFTDAEVVEDFADEFPQV
MMAR_2473|M.marinum_M VAGVLSLTDAARLVSARGRLMAQLPPGGVMVAVAASAAQVAPMLEEG--V
MUL_1655|M.ulcerans_Agy99 VAGVLSLTDAARLVSARGRLMAQLPPGGVMVAVAASAAQVAPMLQEG--V
Mb1692|M.bovis_AF2122/97 VAGALSLVDAARVVAARGRLMQALPAGGVMVAVAASEDEVAPLLTEG--V
Rv1664|M.tuberculosis_H37Rv VAGALSLVDAARVVAARGRLMQALPAGGVMVAVAASEDEVAPLLTEG--V
MAV_3107|M.avium_104 VAGVLSLRDAARLVAARGALMAALPPGGVMVAVTATEAQVAPLVGGG--V
MLBr_00135|M.leprae_Br4923 VAGVLAPADAAMLVVARGRLMQSMPAGGTMWAVAASEDEVVSLLGEG--V
TH_4458|M.thermoresistible__bu VAGVLGLDDAAALLCGRTRLSRLASTG-----------------------
***.:. *.* :: * : . *
Mflv_0405|M.gilvum_PYR-GCK SVGAYNGPN-TVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDP
MAB_0939|M.abscessus_ATCC_1997 SVGAYNGPN-TVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDP
MSMEG_0408|M.smegmatis_MC2_155 SVGAYNGPN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDP
Mvan_1003|M.vanbaalenii_PYR-1 SVAAYNGPN-TVLAGPASDLEQIVAGCSGEGIRTTWLDTSHAFHSALLDP
MMAR_2473|M.marinum_M SIAAVNGPDSVVISGPEAATAVVADRLTGQGCRAHRLAVSHAFHSALMEP
MUL_1655|M.ulcerans_Agy99 SIAAVNGPDSVVISGPEAATAVVADRLTGQGCRAHRLAVSHAFHSALMEP
Mb1692|M.bovis_AF2122/97 CIAAVNAPESVVISGEQAAVGVVVDRLVGLGRRVRRLAVSHAFHSVLMDP
Rv1664|M.tuberculosis_H37Rv CIAAVNAPESVVISGEQAAVGVVVDRLVGLGRRVRRLAVSHAFHSVLMDP
MAV_3107|M.avium_104 SIAAVNGPDAVVLSGEQEAVSAVAERLAGSGARVHRLAVSHAFHSALMEP
MLBr_00135|M.leprae_Br4923 GIAAINAPESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEP
TH_4458|M.thermoresistible__bu -------------------------------------------------A
.
Mflv_0405|M.gilvum_PYR-GCK VLDEFESYAAQLQFAAPTLPLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQ
MAB_0939|M.abscessus_ATCC_1997 ILDEFESYAAQVQFAAPTLPLVCNRTGAVLTAQTPIDGQYWRRHSRQPVQ
MSMEG_0408|M.smegmatis_MC2_155 VLDEFEAYAAQFQFAAPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQ
Mvan_1003|M.vanbaalenii_PYR-1 VLDEFESCAARLAYAAPTRPLVCNRTGAVVTGPGVIDAQYWRRHARQPVQ
MMAR_2473|M.marinum_M MMAQFGATISGIVAHEPRIALVSTMTG-QLAAAGYGTASYWVEHVRKPVR
MUL_1655|M.ulcerans_Agy99 MMVQFGATISGIVAHEPRIALVSNMTG-QLAAAGYGTASYWVEHVRKPVR
Mb1692|M.bovis_AF2122/97 MVEEFSKVLADVCVRAPRIGLVSNVTG-QLAGAGYGSPAYWVEHVRKPVR
Rv1664|M.tuberculosis_H37Rv MVEEFSKVLADVCVRAPRIGLVSNVTG-QLAGAGYGSPAYWVEHVRKPVR
MAV_3107|M.avium_104 MLDGFAAAAAGIEPRPPRIPLVSNLTG-QLAGPGYGTPQYWVEHVRRPVR
MLBr_00135|M.leprae_Br4923 MLEEFVRVAAQVEVRKPQIGLVSNVTG-ELAGPDFGSPQYWGEHVSRAVR
TH_4458|M.thermoresistible__bu VREGLDGLLANLRPDDPRIPLYSTVTGDAVTGRGFG-AAHWMENLHSPVR
: : : . * * .. ** ::. :* .: .*:
Mflv_0405|M.gilvum_PYR-GCK FAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIASLRKGV
MAB_0939|M.abscessus_ATCC_1997 FAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPRAIVSLRKGV
MSMEG_0408|M.smegmatis_MC2_155 FAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGV
Mvan_1003|M.vanbaalenii_PYR-1 FAESVRTLADLGCSVLMEIGPQPFLIAAALRVWPESAATPRAIPSLRKGP
MMAR_2473|M.marinum_M FADGVALAESLGAATFLETGPSAGLGTSV--------------ALLAKGR
MUL_1655|M.ulcerans_Agy99 FADGVALAESLGAATFLETGPSAGLGTSV--------------ALLAKGR
Mb1692|M.bovis_AF2122/97 FFDGVGLAESLGARVFVEVGPGAGLEASV--------------ALLARDR
Rv1664|M.tuberculosis_H37Rv FFDGVGLAESLGARVFVEVGPGAGLEASV--------------ALLARDR
MAV_3107|M.avium_104 FVDGVRLAESQGAGVFLEVGPGAALTAAVDQSLSTEGAT--AIATLPKDR
MLBr_00135|M.leprae_Br4923 FVDSARHLQTLGATHFIESGPSSGLMGAIEQSLAPAEAV--VVSMMGKDR
TH_4458|M.thermoresistible__bu FSAAVRRLLGRGHDAFLEISAHPMLLSAVQEDAADLGRSCTTLVSMRRGE
* .. * ::* .. . * : : :.
Mflv_0405|M.gilvum_PYR-GCK ADRRQIADALAAAYIGGHKPDFAALHEQ-RGVRLELPTYPFQRRRFWPKS
MAB_0939|M.abscessus_ATCC_1997 EDRRQIADALASAYVSGHRPNFAALQRH-PRRTVELPTYPFQRRRFWPKS
MSMEG_0408|M.smegmatis_MC2_155 ADRRQIADALASAYVGGHRPDFAAVHRQ-PRRPVELPTYPFQRRRFWPKA
Mvan_1003|M.vanbaalenii_PYR-1 DARRQLAEAVAAAYIAGHRLDFTGHDGG-PHRRLPLPTYPFQHRSYWPKT
MMAR_2473|M.marinum_M PEVESLLTAMGQLYVDGADLDWRAAFAGLRARTVTLPTYSFARQRFWLG-
MUL_1655|M.ulcerans_Agy99 PEVESLLTAMGQLYVDGADLDWRAAFAGLRARTVTLPTYSFARQRFWLG-
Mb1692|M.bovis_AF2122/97 PEVESVLAGVGRLFAEGVAVDWSSVFAGLGGRRVELPTYGFARQRFWLG-
Rv1664|M.tuberculosis_H37Rv PEVESVLAGVGRLFAEGVAVDWSSVFAGLGGRRVELPTYGFARQRFWLG-
MAV_3107|M.avium_104 PETESALHAAGHLFTRGHRLDWAGVFAGLPARRVDLPTYAFARERFWLGG
MLBr_00135|M.leprae_Br4923 PELASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETP
TH_4458|M.thermoresistible__bu CGRDVLMTSLAALYASGHAVDWARVHPH-GSHCTAAPTYPWQRQRFWLDI
. . : * :: *** : :. :*
Mflv_0405|M.gilvum_PYR-GCK AGMAIDGRVGASAGSGILGSGKDLASGDSVYTSRLSVKTQPWLSDHVIYG
MAB_0939|M.abscessus_ATCC_1997 SGTAIEG--GGGLPSGILGRGEDLASGDSVYISRLSVRSQPWLSDHVIYG
MSMEG_0408|M.smegmatis_MC2_155 SSIAVDG---GTAASGILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYG
Mvan_1003|M.vanbaalenii_PYR-1 AGIRSDG----SSGSGLLGSAQDLASGDIVHTSRLSVKTQPWLSDHVIYG
MMAR_2473|M.marinum_M ------------EGAGRKAD----SSDESGLRPRLDSVDS----------
MUL_1655|M.ulcerans_Agy99 ------------EGAGRKAD----SSDESGLRPRLDSVDS----------
Mb1692|M.bovis_AF2122/97 -----------DNGELSVDQ----TGKDAGAIARLQSLAP----------
Rv1664|M.tuberculosis_H37Rv -----------DNGELSVDQ----TGKDAGAIARLQSLAP----------
MAV_3107|M.avium_104 ASL-----AGAPAGAAPVGG----GTRAPELAHRLHALPR----------
MLBr_00135|M.leprae_Br4923 G----------TDGTASVSG----LGLGSTEHALLGAVVERPDSGGVVLT
TH_4458|M.thermoresistible__bu DRCDTG------DGAGTGGTAERTVVPAPLPAPSASAAPTVDEVLLCAD-
Mflv_0405|M.gilvum_PYR-GCK --------------------TVVVPGATYAAMALAAVGTPAHAKDVFFYE
MAB_0939|M.abscessus_ATCC_1997 --------------------TVVVPGATYAAMALAAVGTPARAKDVFFYE
MSMEG_0408|M.smegmatis_MC2_155 --------------------TVVVPGATYAAMALAAVGTPARLKDVFFYE
Mvan_1003|M.vanbaalenii_PYR-1 --------------------TVVVPGATYAAMALAAMPTPARVQEVFFYE
MMAR_2473|M.marinum_M -----------------------------------KERFRQLVDLVCLHA
MUL_1655|M.ulcerans_Agy99 -----------------------------------KERFRQLVDLVCLHA
Mb1692|M.bovis_AF2122/97 -----------------------------------PELQRQLVELVCFHA
Rv1664|M.tuberculosis_H37Rv -----------------------------------PELQRQLVELVCFHA
MAV_3107|M.avium_104 -----------------------------------DEQQRVLRELVCEHA
MLBr_00135|M.leprae_Br4923 GRLSLANQPWLADHVIGGVVLFPGAGFVELVIRAGDEVGCAGVEELVLAA
TH_4458|M.thermoresistible__bu -----------------------------------QRERRELLESYLRDR
.
Mflv_0405|M.gilvum_PYR-GCK PIILPEKSSREVQLTVHPSVDGE-SKFQVHSRPYGERGAEWALNAEGVVA
MAB_0939|M.abscessus_ATCC_1997 PIILPEKSSREVQLTLHPLEDGSGSKFQVHSRPYGERDVDWSLNAEGTVV
MSMEG_0408|M.smegmatis_MC2_155 PIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVD
Mvan_1003|M.vanbaalenii_PYR-1 PIILGDKDSREVQLMLHRTDDADGWTFEVHSRPYGDRDADWSRNASGTVA
MMAR_2473|M.marinum_M AIVTGHSNSHQIDAERAFQDLG----------------------------
MUL_1655|M.ulcerans_Agy99 AIATGHSNSHQIDAERAFQGLG----------------------------
Mb1692|M.bovis_AF2122/97 AIVLGRKSSHDIDPECAFQDLG----------------------------
Rv1664|M.tuberculosis_H37Rv AIVLGRKSSHDIDPECAFQDLG----------------------------
MAV_3107|M.avium_104 AAVLGHPGGDAIDPDRAFADLG----------------------------
MLBr_00135|M.leprae_Br4923 PLVLHPGSGVQVQVVVAAADESSRRAVSVYSRGDQSHGGWLLNAEGLLEV
TH_4458|M.thermoresistible__bu VAAELGVLPPLLDVAAPLSTLG----------------------------
:: .
Mflv_0405|M.gilvum_PYR-GCK SGVGD-------SPAAAGDLEDPVDEAIERLNRMRPQELFETFADLELAW
MAB_0939|M.abscessus_ATCC_1997 TGIGDDAE----PAPEAAEPAEPVDAAIERMERMRPMELFEIFADLELAW
MSMEG_0408|M.smegmatis_MC2_155 TAGSD-------PDAAADEQSDPVDEVIERLERMRPQDLFETFADLELAW
Mvan_1003|M.vanbaalenii_PYR-1 AGVGD---------AAPDAAADPVDNAIERLTRTRPQQLFDAFADNDLAW
MMAR_2473|M.marinum_M ---------------------------------------FESMTGVELRN
MUL_1655|M.ulcerans_Agy99 ---------------------------------------FESMTGVELRN
Mb1692|M.bovis_AF2122/97 ---------------------------------------FDSMSGVELRN
Rv1664|M.tuberculosis_H37Rv ---------------------------------------FDSMSGVELRN
MAV_3107|M.avium_104 ---------------------------------------FDSLIGVELRN
MLBr_00135|M.leprae_Br4923 DAAEATVDLSLWPPEGAESVDISDAYPQLAERGYAYGPAFQGLVAIWRRG
TH_4458|M.thermoresistible__bu ---------------------------------------IDSLTAAELRA
:: :
Mflv_0405|M.gilvum_PYR-GCK GPTWSGSLKSLWLGEGEAIGDILVGAELAEQLGTEPMHPVLMDLCTGVAF
MAB_0939|M.abscessus_ATCC_1997 GPTWSGSLKSLWLGEGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAF
MSMEG_0408|M.smegmatis_MC2_155 GPTWSGSLKSLWLGDGEAVGDILVGAELAEQLGSEPMHPVLMDLCTGVAF
Mvan_1003|M.vanbaalenii_PYR-1 GPAWCSSLRSLWVGTGEAVGDIAVGAELGEHLGREPIHPVLLDLCTGIAG
MMAR_2473|M.marinum_M R----------------------------------------LRAVT---G
MUL_1655|M.ulcerans_Agy99 R----------------------------------------LRAVT---G
Mb1692|M.bovis_AF2122/97 R----------------------------------------LQMAIGLPG
Rv1664|M.tuberculosis_H37Rv R----------------------------------------LQMAIGLPG
MAV_3107|M.avium_104 R----------------------------------------LTTHT---G
MLBr_00135|M.leprae_Br4923 SELFA-----------------EVVAPTGVVVDGMGMHPALLDAVLHALG
TH_4458|M.thermoresistible__bu R------------------------------------VERDLGIVIPVA-
:
Mflv_0405|M.gilvum_PYR-GCK PAFPALLAAEQGVNDLYLPLRYGQVSLQEKMPRRFYCRATWHEAPLDSET
MAB_0939|M.abscessus_ATCC_1997 PAFPALLAAEQGVNDLFLPLRYGQVTLKEKMPRRFYCRARWHESPLDSET
MSMEG_0408|M.smegmatis_MC2_155 PAFPALLAAEQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSET
Mvan_1003|M.vanbaalenii_PYR-1 AALLAAAAQTDADPELFLPLRYGRVEVRERMPRRFYCRARWQTGGIDSET
MMAR_2473|M.marinum_M LALSRT--------------------------------------------
MUL_1655|M.ulcerans_Agy99 LALSRT--------------------------------------------
Mb1692|M.bovis_AF2122/97 LSLPRT--------------------------------------------
Rv1664|M.tuberculosis_H37Rv LSLPRT--------------------------------------------
MAV_3107|M.avium_104 TALSRT--------------------------------------------
MLBr_00135|M.leprae_Br4923 LAIENTQATTEMRLPFCWRGVS----------LHAGGAGRVRARFTSAGA
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK QVFDLEYLDRDGRHLGGVREFTVKRAPREALLRGLGGDATRLLYTLGWHE
MAB_0939|M.abscessus_ATCC_1997 QVFDLDYLDRDGRHLGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHE
MSMEG_0408|M.smegmatis_MC2_155 QVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHE
Mvan_1003|M.vanbaalenii_PYR-1 QVFDLDFLDHDGRNLGGIREFTVKRAPREALLRGLGADATRLIYRVGWRE
MMAR_2473|M.marinum_M ----------------IIFDYPTPMALARHLDEQLSGG------------
MUL_1655|M.ulcerans_Agy99 ----------------IIFDYTTPMALARHLDEQLSGG------------
Mb1692|M.bovis_AF2122/97 ----------------LIFDYPTASALAECLG-QLLGG------------
Rv1664|M.tuberculosis_H37Rv ----------------LIFDYPTASALAECLG-QLLGG------------
MAV_3107|M.avium_104 ----------------LIFDYPTPAALADHLRQQLLHD------------
MLBr_00135|M.leprae_Br4923 DAIAVDIADSAGLPVLTVRSLVTRAMTAEQLRTAVTAAGG----------
TH_4458|M.thermoresistible__bu ----------------QLLNGPSVSDLAEWISTTMVGFG-----------
: . : :
Mflv_0405|M.gilvum_PYR-GCK VPVP----ESGDGAAPQGTWLIGGFDELAVSVPGCIPADR----------
MAB_0939|M.abscessus_ATCC_1997 VAVPPVAGEGEESAASIGTWLIAGFDELAAKVPGCIPLNRE---------
MSMEG_0408|M.smegmatis_MC2_155 VPPP------PSADDAVGTWLIAGFDELAAKVPGCVPIDRN---------
Mvan_1003|M.vanbaalenii_PYR-1 TSPP---VRDDGALGPSSTWLVAGLDALADDVPGSIRIGFDRIWDPDRDG
MMAR_2473|M.marinum_M ---------NHEESDDDKIWSVLRT-------------------------
MUL_1655|M.ulcerans_Agy99 ---------NHEESDDDKIWSVLRT-------------------------
Mb1692|M.bovis_AF2122/97 ---------QHESSDDESIWQLLKN-------------------------
Rv1664|M.tuberculosis_H37Rv ---------QHESSDDESIWQLLKN-------------------------
MAV_3107|M.avium_104 ---------EDPESDDERIWSALRR-------------------------
MLBr_00135|M.leprae_Br4923 ---------ALEQGPMDLVWSPIPLSSDGHGGGLPSVVSWA---------
TH_4458|M.thermoresistible__bu ----------STTPEPESAGVPGRS-------------------------
Mflv_0405|M.gilvum_PYR-GCK ------TNPESLRQLLTDAHGRGLPFSGVVWRAARSDGDES--DAEVAAR
MAB_0939|M.abscessus_ATCC_1997 ------TDPELLGEVLVAAKERGVPFSGVVWRAAGPGATES--TTESAAR
MSMEG_0408|M.smegmatis_MC2_155 ------TDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKESGSASAESAR
Mvan_1003|M.vanbaalenii_PYR-1 RVVLDPADDEHWRRLFALADERRAPVAGVVLGVTGRARPEE-PSADFAAR
MMAR_2473|M.marinum_M ----------------------------IPVRELRRS-------------
MUL_1655|M.ulcerans_Agy99 ----------------------------IPVRELRRS-------------
Mb1692|M.bovis_AF2122/97 ----------------------------IPIHQLRRT-------------
Rv1664|M.tuberculosis_H37Rv ----------------------------IPIHQLRRT-------------
MAV_3107|M.avium_104 ----------------------------IPLRELRRT-------------
MLBr_00135|M.leprae_Br4923 -----------------DYCAGRGNDTGVVVWEFGSASAGAQAPVDSVAA
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LEAEIAELLGAVHTVQ---GGEVKLPGGLWIVTERAVATESGEPVDPVQA
MAB_0939|M.abscessus_ATCC_1997 LEGEIAHLLSAVHTVQNSAQNGVKLPGGLWIVTERAVATESGEPVDPVQA
MSMEG_0408|M.smegmatis_MC2_155 LEAEITNLLSAVHAAQ---GPSVKLPGGLWIVTEHGVACESGEPVDPVQA
Mvan_1003|M.vanbaalenii_PYR-1 LEAQIRDVLGAVHSLS---ALGAKPAAGLWIVTERAVAAEAGEPVDPVQS
MMAR_2473|M.marinum_M ------GMLDKLLLLA-----GQDES------PAPDAAVSDDVIDSLSPE
MUL_1655|M.ulcerans_Agy99 ------GMLDKLLLLA-----GQDER------PAPDAAVSDDVIDSLSPE
Mb1692|M.bovis_AF2122/97 ------GLLDKLLLLA-----GQPEE------SLAGRTVSDEVIDSLSPE
Rv1664|M.tuberculosis_H37Rv ------GLLDKLLLLA-----GQPEE------SLAGRTVSDEVIDSLSPE
MAV_3107|M.avium_104 ------GLLDKLLLLA-----GMPET------ATTDAKISDADIDSLSPD
MLBr_00135|M.leprae_Br4923 VYSATHAALQVLQFWF-----GQDRAGTLVVLTRGAVGLVGEGISDLAAA
TH_4458|M.thermoresistible__bu ------RPPDGAVASG-------SGDGGRWIELLNQMPEVSDDTVDELLR
.
Mflv_0405|M.gilvum_PYR-GCK ALWGFGRTAINEEPALRCRLVDCDGSPQAVQALAALLSTP-VDEPELAVR
MAB_0939|M.abscessus_ATCC_1997 ALWGFGRTTINEEPALRAKLVDGDGSPEAVQALARLLVTP-VDEPEIAVR
MSMEG_0408|M.smegmatis_MC2_155 ALWGFGRTTINEEPALHCRLVDCDGSSEAVDLLAALLAAPGIQEPEIAVR
Mvan_1003|M.vanbaalenii_PYR-1 ALWGLGRTLIAEEPGLRCLLVDLDGSEDAGPALARLLGAP-GDEPELALR
MMAR_2473|M.marinum_M ALVAMALDSEDDDPD-----------------------------------
MUL_1655|M.ulcerans_Agy99 ALVAMALDSEDDDPD-----------------------------------
Mb1692|M.bovis_AF2122/97 ALIGLALDEDENDIR-----------------------------------
Rv1664|M.tuberculosis_H37Rv ALIGLALDEDENDIR-----------------------------------
MAV_3107|M.avium_104 ALIAMALNSADDDEAE----------------------------------
MLBr_00135|M.leprae_Br4923 AVWGMVRSAQSEHSGKIVLIDT--------DSAVDVAVLADLGESQLLVR
TH_4458|M.thermoresistible__bu QLLAAGENHDDTQLH-----------------------------------
: . .
Mflv_0405|M.gilvum_PYR-GCK QGKLLASRLLPWSRSGHLTVPRGGDYVLAPTERGAIDNLRLTDSEVPPP-
MAB_0939|M.abscessus_ATCC_1997 QGKLLASRLLPWSRTGHLTVPRGSDYVLAPTERGAIDNLRITEKEVPAP-
MSMEG_0408|M.smegmatis_MC2_155 QGKLLASRLLPWARSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVPEP-
Mvan_1003|M.vanbaalenii_PYR-1 QGRLLVPRLLPWSRSGQLAIPRGTDYVLAPTERGVLDNLRVSETEVTAP-
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 CNTVHAARLSPAPQLLALPVGESMWRLAADGGGTLEDLVIQPCPEVQAPL
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGEGVTG
MAB_0939|M.abscessus_ATCC_1997 DEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGIVTQLGEGVTG
MSMEG_0408|M.smegmatis_MC2_155 DEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSG
Mvan_1003|M.vanbaalenii_PYR-1 PEGHVQVRVEAAGLNFRDVLNALGLYPGDPGPIGGELAGVVTAPGPDVDG
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 QAGHMRVAVAAVGVNFRDVVAALGMYPGQAPPLGAEGAGVVIEIGPEVTG
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LDVGQRVYGSMQGAFASRFNVPGQFLAPIPDGVSAVEAATIPAAALTVR-
MAB_0939|M.abscessus_ATCC_1997 VEVGQRVYGSMQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVR-
MSMEG_0408|M.smegmatis_MC2_155 LEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVR-
Mvan_1003|M.vanbaalenii_PYR-1 FDVGQRVFGFAVGAFASRVNVPVQFLAPVPEGISAVAAATTPAAVLTAG-
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 VAVGDAVMGFLGGAGPLAV-VHQQLITQMPQGWSLAEAAAVPVVFLTALF
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK LSFDWAQVKSGDKVLIHAASGGVGLAAVQMAQQCGAEVYATASTFKRATL
MAB_0939|M.abscessus_ATCC_1997 LSFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQFGAEVFATASTFKRATL
MSMEG_0408|M.smegmatis_MC2_155 LAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTL
Mvan_1003|M.vanbaalenii_PYR-1 LAFDWAALRAGDRVLIHAASGGVGLAAVQLARQRGATVFATASGYKRPML
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 GLADLAGIRAGESVLIHAGTGGVGMAAVQFARHWGVEIFVTASRGKWDTL
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK RKLG--VKHVYDSRTTDFAEQILADTDGAGVDVVLNSLTSEGFIEATLRA
MAB_0939|M.abscessus_ATCC_1997 RKLG--VKYVYDSRTTDFADQILADTDGAGVDVVLNSLTSEGFIEATLRA
MSMEG_0408|M.smegmatis_MC2_155 RRLG--VKYVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKA
Mvan_1003|M.vanbaalenii_PYR-1 RAMG--VDHVYDSRTTDFADQILADTDGAGVDVVLNSLTNDGFVAATVRA
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 RDMGFDDDHIGDSRTLEFEEKFLAVTDGRGVDVVLDSLAGD-FVDASLRL
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK TAQHGRFAEIAKRDIWTVEQMAAARPDLAYEIVALDTVMFTEPDRIRDLL
MAB_0939|M.abscessus_ATCC_1997 TAKNGRFAEIAKRDIWTTEQMAQSRPDIAYEIVALDTVMFQEPDRIRVLL
MSMEG_0408|M.smegmatis_MC2_155 TAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLL
Mvan_1003|M.vanbaalenii_PYR-1 TARNGRFAEIAKRDIWSPEQMAAARPDIDYEVLALDAVMQQDPDRIQLLL
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 LVRGGRFLEMGKTDIRDAQEIAANYPGVQYRAFDLSEAG---PVRMQEML
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK TEVSAGLRDGAWTPLPAEVYPLTEARAAFRRMQQARHIGKIVVQIPNPLQ
MAB_0939|M.abscessus_ATCC_1997 TEVSEGLAKGEWTPLPAEIYPLTEARTAFRRMQQARHIGKIVCQMPNPLA
MSMEG_0408|M.smegmatis_MC2_155 TEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIVLQVPKPLQ
Mvan_1003|M.vanbaalenii_PYR-1 ADLADSLARGETAPLPFEAYPLAEATTAFRRMQQARHTGKIILQMPKPLQ
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 CEVRELFDTQVLHRLPVTSWDVRCAPAAFRFMSQARHIGKVVLTMPSALA
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK P-QPDRSYLITGGLGAIG-LHTAGYLAQLGAGDIVLTSRRAPDAAAQQAI
MAB_0939|M.abscessus_ATCC_1997 P-RPDRTYLITGGLGAIG-LHTAAYLAQLGAGDIVLTSRRAPDTDAQRVI
MSMEG_0408|M.smegmatis_MC2_155 P-QQDRSYLITGGLGAIG-LHTAAYLAQLGAGDIVLTSRRDPDESAQRAI
Mvan_1003|M.vanbaalenii_PYR-1 P-HGDRSYLITGGLGALG-LHAAAYLAQLGAGDIVLTGRRMPDAATERAI
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 DGLAEGTVLITGASGAIGGVLARHMVSAYGVRHLVLASRRGDRAEGAVEL
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ADIADRTKARLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDD
MAB_0939|M.abscessus_ATCC_1997 GEITERSKTRIHVFTADVGAESEVAGLLERIRAELPPLAGVAHLAGVLDD
MSMEG_0408|M.smegmatis_MC2_155 DEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDD
Mvan_1003|M.vanbaalenii_PYR-1 SEIAERYHCRIHTFAADVGDESAVRDLLERIRTELPPLAGVAHLAGVLDD
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 AAELVGAGAKIQVVACDVADNDAVRGLFAQLSREFPPVRGVIHAAGVLDD
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ALLSQQSVERFRTALAPKAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSP
MAB_0939|M.abscessus_ATCC_1997 ALLGQQSVERFRTTLAPKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGSP
MSMEG_0408|M.smegmatis_MC2_155 ALLSAQNPERFRTTLAPKAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSP
Mvan_1003|M.vanbaalenii_PYR-1 ALLPQQSPERFRTTLAPKAFGAWHLHRLTRDTELEFFIVYSSGSSVLGSP
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 GAITSLTPDRVDTVLRAKVDAAWNLHEATRDLDLLMFVLCSSIAATVGSP
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK GQSNYATANAFLDGLVAQRRAQGLPATGVNFGPWARGGMASSEAAAAN--
MAB_0939|M.abscessus_ATCC_1997 GQSNYATANALLDGLIAQRRAQGLPATGINFGPWGQGGMASSEAATAN--
MSMEG_0408|M.smegmatis_MC2_155 GQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATAN--
Mvan_1003|M.vanbaalenii_PYR-1 GQANYATANAVLDGLVAHRKARGLPATGVNWGPWAQGGMATSDAARAN--
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 GQGNYSAANAFLDGLAAYRQAAGLAGTSLAWGLWEQPGGMNAHLSSRDLA
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK -ISAQGLIPLEPSAALTAMAEVVANGTA-QATVLKANWQRAAKVLGSSRP
MAB_0939|M.abscessus_ATCC_1997 -ISAQGLIPLDPSAALAALAEVVANGTG-QATILKANWQRAAKVLGSSRP
MSMEG_0408|M.smegmatis_MC2_155 -ITAQGLIPLDPSAALHALAEVIANGSG-QATVLKANWQRAAKVLGSARP
Mvan_1003|M.vanbaalenii_PYR-1 -LGAQGLIPLEPTAALNALGEIVAHGIA-SAVVLKANWQRAAKLLGATRP
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 RISRSGLAPMNPAQALELFDAALVIDHPFMVTALLDRAALDAQAQAGALP
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK PILDLVLPSAVGEI--------TGDSELLKQLQEIPVPQRAGFVTEFLQK
MAB_0939|M.abscessus_ATCC_1997 PILDLVLPSAVGEV--------TGDSELLKQLMEIPVPQRAGFVTEFLQR
MSMEG_0408|M.smegmatis_MC2_155 PILDLVLPSAAGEA--------TGDSELLKQLMEIPIPQRAGFVTEFLQR
Mvan_1003|M.vanbaalenii_PYR-1 PILDHVLPSAVAAG--------PGDSALLKQLQDVPEAQRGSFVTEHLQR
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 PLFSRLVRRSRRRQIEDPGDATQSKLALVQRLQGLAANRQLELLVGVVCL
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK EVQNFLRLAQPPAATS--RFLDLGTDSLMAIELRNRLHSQFGGAFTINAT
MAB_0939|M.abscessus_ATCC_1997 EVQNFLRLAQPPAATS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINAT
MSMEG_0408|M.smegmatis_MC2_155 EVQNFLRLASPPAASS--RFLDLGTDSLMAIELRNRLHSQFGGKFTINAT
Mvan_1003|M.vanbaalenii_PYR-1 ELQQILGLAQPPAATG--RFLELGMDSLMAVELRNRLVGQFGSGFTITAT
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 QAAAVLGRPSPEDIDPNTKFQDLGFDSLTAVELRNRLKSATG--LTLPPT
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK AVFDYPTIGGLAEYLVAQLPDAETPQAAP-------QSESEPGPDVTE--
MAB_0939|M.abscessus_ATCC_1997 AVFDYPTIGGLAEYLVGQLPDADAESAEAPPAVESAEAESGAGPAAASDA
MSMEG_0408|M.smegmatis_MC2_155 AVFDYPTIGGLAEYLVGQLPDAEAPETA----------------------
Mvan_1003|M.vanbaalenii_PYR-1 AVFDYPTIGALAEYLAAQTPESTEEGTEMKTADPDGQPATVGHADVVLQT
MMAR_2473|M.marinum_M --------------------------------------------------
MUL_1655|M.ulcerans_Agy99 --------------------------------------------------
Mb1692|M.bovis_AF2122/97 --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3107|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 VIFDHPTPTAVAEYVAQQMLKSRPAESGDETSQAVEPKVEEVSVHA----
TH_4458|M.thermoresistible__bu --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK ------
MAB_0939|M.abscessus_ATCC_1997 VSELKE
MSMEG_0408|M.smegmatis_MC2_155 ------
Mvan_1003|M.vanbaalenii_PYR-1 S-----
MMAR_2473|M.marinum_M ------
MUL_1655|M.ulcerans_Agy99 ------
Mb1692|M.bovis_AF2122/97 ------
Rv1664|M.tuberculosis_H37Rv ------
MAV_3107|M.avium_104 ------
MLBr_00135|M.leprae_Br4923 ------
TH_4458|M.thermoresistible__bu ------