For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTDGLHSADALQEWFTHYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIPGELSDVLGICVPDLAVWDNP SAHDVIKSVLGGDGSQRSADSDTGCAVLGNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEY PARRLGAAAADWLGDEQETIYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRLLLETSWAALEHAGILPKT LKLSHTGVFVGVSSTDYVRLLFPGGRKPTIWDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAH LARKSLASGECDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCGVVVLERLSDA RRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSACKCADIDPAEIDYVEAHGTGTSVGDRIEAH ALGQVFGRGRQAAKPLMIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAELGLA VVEEFQEWPAVVGRPRRAGVSSFGFGGTNAHVIVEQAVERVVERVVEVGPGVLAWVVSARTAAGVGAQAG RLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPGVGVASGVAMPGGKTV FVFPGQGAQWLGMGRELCAGYPVFAAAFDAVVAELDRHLARPLREVVWGADAELLNTTEFAQPALFAVEV ALYRLLESWGMRPGLVMGHSVGELSAAHVSGVLDLADAALLVVMRGRLMQALPGGGVMYAVQAGEQELRP LLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVLMEPMLEQFRAVADEVYA GRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQ VSVVAVPTLRKDRPEPFAVVGAVAQAFVRGAGVDWASVLAGCGGQRVGLPTYAFAHERFWLADRFGVGQQ VCVGQVLADEAGPGAHEAAGAAVGQGFAARLQGLSDAEQQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFS DAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQLADHLLSHLHHQNRSAPAAAVRTRVRIDEPIAI VGMGCRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTYTRHGGFVSDVADFDPG FFGISPGEALAMDPQQRLLLETSWEALEDAGIDPQALRGSSTGVFVGIYGDGYGLGTSQAQWYADTGHIT SVASGRISYCLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSIFIGFSRQRGLA TDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPVLAILAGSAVNQDGASNGLTAPSGPAQQRVIS AALSDAGITGADVDVVEAHGTGTRLGDPIEAQALLATYGRDHTPDAPLWLGSIKSNMGHSQAAAGVAGVI KMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPAVVGRPRRAGVSSFGVSGTNAHVIVEQAV ERVVERVVEVGPGVLAWVVSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYSLVTTRSLFEHRAVVVGAG RDELLAGLAEVVEGRPGVGVASGVAMPGGKTVFVFPGQGAQWLGMGRELCAGYPVFAAAFDAVVAELDRH LARPLREVVWGADAELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAAHVSGVLDLADA ALLVVMRGRLMQALPGGGVMYAVQAGEQELRPLLGEQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGR RVRRLAVSHAFHSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLVAEDYGSADYWVRHIREAVRFAD SVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVVAVPTLRKDRPEPFAVVGAVAQAFVRGAGVDWASV LAGCGGQRVGLPTYAFAHERFWLADRFGVGQQVCVGQVLADEAGPGAHEAAGAAVGQGFAARLQGLSDAE QQAAVLAMVCEHTAAVLGRDGAAQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTAFDYPTPTQL ADHLLSHLHHQNPTGATPELDRVDALTDLFLQTCDAGRDDDGWQIVALAANGRERMTTPVPKREWKEVVL LAGGRSDVAVVCLPTLTVLSSPHAYLDVARAMAGRHSVHALSLPGFDPDDALPQDREVVLEGAAQAILHA VGDHPHLVLAGYSSGGVLAHALGSYLAERHQRTPLGVALIDTYLPSQIVNADNPDQVGVNETGALFSRRV TSMARELDQLNATRLTAAASYAALFGTWEPVVSAVPLLNMIAMDETAACERVRAERINRWRVATAEASYS VVEVPGDHFDMITTSSDATTTALHGWISGLIRAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0707 | pks6 | - | 100% (2414) | polyketide synthase Pks6 |
| M. marinum M | MMAR_3025 | pks12 | 0.0 | 61.90% (1042) | polyketide synthase, Pks12 |
| M. marinum M | MMAR_0101 | - | 0.0 | 61.77% (994) | polyketide synthase PKS |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2074c | pks12 | 0.0 | 62.52% (1030) | polyketide synthase pks12 |
| M. gilvum PYR-GCK | Mflv_0405 | - | 0.0 | 41.86% (1094) | beta-ketoacyl synthase |
| M. tuberculosis H37Rv | Rv0405 | pks6 | 0.0 | 56.64% (1379) | membrane bound polyketide synthase |
| M. leprae Br4923 | MLBr_00135 | - | 0.0 | 64.19% (874) | putative polyketide synthase |
| M. abscessus ATCC 19977 | MAB_0939 | - | 0.0 | 41.94% (1085) | polyketide synthase |
| M. avium 104 | MAV_2450 | - | 0.0 | 63.18% (1032) | erythronolide synthase, modules 3 and 4 |
| M. smegmatis MC2 155 | MSMEG_0408 | - | 0.0 | 41.51% (1125) | type I modular polyketide synthase |
| M. thermoresistible (build 8) | TH_4621 | - | 1e-170 | 40.60% (894) | PUTATIVE mycocerosic acid synthase |
| M. ulcerans Agy99 | MUL_2266 | pks12 | 0.0 | 61.59% (1044) | polyketide synthase, Pks12 |
| M. vanbaalenii PYR-1 | Mvan_0269 | - | 0.0 | 44.39% (1016) | beta-ketoacyl synthase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0707|M.marinum_M MTDGLHSADALQEWFTHYIAARTGCDSAEVNLDLPLRDLGLGSIDVLAIP
Rv0405|M.tuberculosis_H37Rv MTDGSVTADKLQKWFREYLSTHIECHPNEVSLDVPIRDLGLKSIDVLAIP
Mb2074c|M.bovis_AF2122/97 --------------------------------------------------
MUL_2266|M.ulcerans_Agy99 --------------------------------------------------
MAV_2450|M.avium_104 --------------------------------------------------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M GELSDVLGICVPDLAVWDNPSAHDVIKSVLG--GDGSQRSADSDTGCAVL
Rv0405|M.tuberculosis_H37Rv GDLGDRFGFCIPDLAVWDNPSANDLIDSLLNQRSADSLRESHGHADRNTQ
Mb2074c|M.bovis_AF2122/97 ---------MVDQLQHATEALRKALVQVERLKRTNRALLERS--------
MUL_2266|M.ulcerans_Agy99 ---------MVDQLQHATEALRKALVQVERLKRTKRALLERS--------
MAV_2450|M.avium_104 --------MMVDQLQHATEALRKALVQVERLKRTNRALLERS--------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 ----------MDSAENPIES------------------------------
Mvan_0269|M.vanbaalenii_PYR-1 ----------MGSAEHPNGP------------------------------
Mflv_0405|M.gilvum_PYR-GCK ----------MGSAAHQGES------------------------------
MSMEG_0408|M.smegmatis_MC2_155 ----------MVSAEHPIEP------------------------------
TH_4621|M.thermoresistible__bu ----------VNIVGDTPVN------------------------------
MMAR_0707|M.marinum_M GNGPTNEPIAVIGMACRFSGQVHGVGPLWDFLAEKKSAITEYPARRLGAA
Rv0405|M.tuberculosis_H37Rv GRGSINEPVAVIGVGCRFPGDIDGPERLWDFLTEKKCAITAYPDR--GFT
Mb2074c|M.bovis_AF2122/97 -----SEPIAIVGMSCRFPGGVDSPEGLWQMVADARDVMSEFPTDR-GWD
MUL_2266|M.ulcerans_Agy99 -----SEPIAIVGMSCRFPGGVDSPEGLWQMVAEGRDVMSDFPTDR-GWD
MAV_2450|M.avium_104 -----SEPIAIVGMSCRFPGGVDSPEALWQMVAEGRDVISEFPTDR-GWD
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 -----TPRFAIIGYAARFPG-AADAEEFWDVLREGRDAISEVPADR--WD
Mvan_0269|M.vanbaalenii_PYR-1 -----APRFAIVGYAARFPG-APDADAFWDVLREGRDAISDVPRDR--WD
Mflv_0405|M.gilvum_PYR-GCK -----AHRFAIVGYAGRFPG-ARDAESFWELLADGRDAISEVPEDR--WD
MSMEG_0408|M.smegmatis_MC2_155 -----TPSFAIIGYAARFPG-AASAEEYWALLRDGREAISDVPKDR--WD
TH_4621|M.thermoresistible__bu -------AVAVIGMACRLPGGIDSPQRLWEALLRGDDMVTEIPVDR--WD
MMAR_0707|M.marinum_M AADWLGDEQET------IYGCFLEDVEGFDNKFFDIPPDEAALMDPQQRL
Rv0405|M.tuberculosis_H37Rv NAGTFAES-----------GGFLKDVAGFDNRFFDIPPDEALRMDPQQRL
Mb2074c|M.bovis_AF2122/97 LAGLFDPDPDVRHKSYARTGGFVDGVADFDPAFFGISPSEALAMDPQHRM
MUL_2266|M.ulcerans_Agy99 LADLFDPDPDTPHKSYASTGGFVDGVADFDPGFFGIAPSEALAMDPQHRM
MAV_2450|M.avium_104 LAALYDPDPDARHKCYVNTGGFVDNVADFDPAFFGIAPSEALAMDPQHRM
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 AEEFFDPEPGAPGKVVTRRAGFVEDVTGFDAPFFGMSTREVRLMDPQHRL
Mvan_0269|M.vanbaalenii_PYR-1 AEEFFDPEPGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRMMDPQHRL
Mflv_0405|M.gilvum_PYR-GCK VEAFFDPDPSTPGKVVTRRAGFVDDVSGFDAPFFGMSTREVRLMDPQHRL
MSMEG_0408|M.smegmatis_MC2_155 IEEFFDPDPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRI
TH_4621|M.thermoresistible__bu ADDYFDPEPGVPGRTVSRWGAFLDDVAGFDPEFFGISEREAISIDPQQRL
MMAR_0707|M.marinum_M LLETSWAALEHAGILPKTLKLSHTGVFVGVSSTDYVRLLFPGGR--KPTI
Rv0405|M.tuberculosis_H37Rv LLEVSWEALEHAGIIPESLRLSRTGVFVGVSSTDYVRLVSASAQQ-KSTI
Mb2074c|M.bovis_AF2122/97 LLELSWEALERAGIDPTGLRGSATGVFAGLIVGGYGMLAEEIEG------
MUL_2266|M.ulcerans_Agy99 LLELSWEALERSGIDPTGLRGSATGVFAGLIVQGYGMFAEEIEG------
MAV_2450|M.avium_104 LLELSWEALERAGIDPSGLRGSATGVFAGLIVQGYGMLAEEIEG------
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 LLETAWRAVEHSGIAPTDLAETNSGVFVGLATHDYLGMASDELTFPEIEA
Mvan_0269|M.vanbaalenii_PYR-1 LLETAWRAVEHSGTAPTALAGSNTGVFVGLATHDYLGMASDELTYPEIEA
Mflv_0405|M.gilvum_PYR-GCK LLETAWRAIEHSGTAPSELANTNTGVFVGLATHDYLGMASDELSYPEIEA
MSMEG_0408|M.smegmatis_MC2_155 LMETAWRAVEHSGIAPTSLANSNTGVFVGLATHDYLGMASDELTYPEIEA
TH_4621|M.thermoresistible__bu LLETSWEAMEHAGLTPADVEGSSTGVFVGLSHDDYALLTSDAGAL--EEA
MMAR_0707|M.marinum_M WDNTGGSSSIIANRLSYFLDVNGPSLVIDTACSSSLVAAHLARKSLASGE
Rv0405|M.tuberculosis_H37Rv WDNTGGSSSIIANRISYFLDIQGPSIVIDTACSSSLVAVHLACRSLSTWD
Mb2074c|M.bovis_AF2122/97 YRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVGSLRSGE
MUL_2266|M.ulcerans_Agy99 YRLTGMTSSVASGRVAYVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGE
MAV_2450|M.avium_104 YRLTGMTSSVASGRVSYVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGE
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 YMAIGTSNAAAAGRISYRLGLQGPSVAVDTACSSSLVAIHQACQALQLGE
Mvan_0269|M.vanbaalenii_PYR-1 YMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRLGE
Mflv_0405|M.gilvum_PYR-GCK YMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRLGE
MSMEG_0408|M.smegmatis_MC2_155 YMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRLNE
TH_4621|M.thermoresistible__bu YGFTGSAFSMASGRIAYRLGVHGPAVTVDTACSSSLLAVHMACRSLQVGE
MMAR_0707|M.marinum_M CDLAVVAGTNVLISPEVWRGFQEAGVVSPTGSCRAFDARADGMVRGEGCG
Rv0405|M.tuberculosis_H37Rv CDIALVGGTNVLISPEPWGGFREAGILSQTGCCHAFDKSADGMVRGEGCG
Mb2074c|M.bovis_AF2122/97 CDLALAGGVTVNATPTVFVEFSRHRGLAPDGRCKPYAGRADGVGWSEGGG
MUL_2266|M.ulcerans_Agy99 CDLALAGGATVNATPTVFVEFSRHRGLAPDGRSKAYAGAADGVGWSEGGA
MAV_2450|M.avium_104 CDLALAGGATVNATPTVFVEFSRHRGLAPDGRCKAYAGAADGVGWSEGGA
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 CDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDAAADGYVRGEGSG
Mvan_0269|M.vanbaalenii_PYR-1 CDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG
Mflv_0405|M.gilvum_PYR-GCK CDLALAGGANVILTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG
MSMEG_0408|M.smegmatis_MC2_155 CDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEGCG
TH_4621|M.thermoresistible__bu SDLALAGGAMVMLEPRKYTSASGLGMLSPTGRCHAFDVAADGFVRSEGSV
MMAR_0707|M.marinum_M VVVLERLSDARRAGRTVLAVLTGSAVNQDGRSNGIMAPNPRAQISVLDSA
Rv0405|M.tuberculosis_H37Rv VIVLQRLSDARLEGRRILAILTGSAVNQDGKSNGIMAPNPSAQIGVLENA
Mb2074c|M.bovis_AF2122/97 MLVLQRLSDARRLGHPVLAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAA
MUL_2266|M.ulcerans_Agy99 MLVVERLSDAQRLGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRVVRAA
MAV_2450|M.avium_104 MLVVERLSDARRLGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRAA
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 VIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADA
Mvan_0269|M.vanbaalenii_PYR-1 VIVIKRLEDAVRDGDRIRAVIRGSSINQDGASGGLTVPNGVAQQRVIADA
Mflv_0405|M.gilvum_PYR-GCK VIVIKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIGDA
MSMEG_0408|M.smegmatis_MC2_155 VVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIADA
TH_4621|M.thermoresistible__bu MLLLKRLPDALRDNDRILAVVRGTAANQDGRTENISTPSIQAQADVYRSA
MMAR_0707|M.marinum_M CKCADIDPAEIDYVEAHGTGTSVGDRIEAHALGQVFGRGRQAA----KPL
Rv0405|M.tuberculosis_H37Rv CKSARVDPLEIGYVEAHGTGTSLGDRIEAHALGMVFGRKRPGS----GPL
Mb2074c|M.bovis_AF2122/97 LANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGEP---GEPL
MUL_2266|M.ulcerans_Agy99 LANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGSAGAAGKAL
MAV_2450|M.avium_104 LANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGQP------L
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 LKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAGAAYGIGRETN----DPL
Mvan_0269|M.vanbaalenii_PYR-1 LKRSDLEPKDVGYLEAHGTGTSLGDPIEAQAAGAVLGAGREPS----RPL
Mflv_0405|M.gilvum_PYR-GCK LSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAGAALGPGREPQ----RPL
MSMEG_0408|M.smegmatis_MC2_155 LKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPE----EPL
TH_4621|M.thermoresistible__bu LAVAGVDPATVGMVEAHGTGTPVGDPIEYNSLTQVYGKTGPCA-------
MMAR_0707|M.marinum_M MIGSIKPNIGHLEGAAGIAGLIKTVLMLQRGQLLPSGAFEVPNPNIPFAE
Rv0405|M.tuberculosis_H37Rv MIGSIKPNIGHLEGAAGIAGLIKAVLMVERGSLLPSGGFTEPNPAIPFTE
Mb2074c|M.bovis_AF2122/97 WLGSVKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDVPSPHVDWSA
MUL_2266|M.ulcerans_Agy99 WLGSIKSNMGHTQAAAGVAGVIKMVQAMRHEVLPATLHVDVPSPHVDWSA
MAV_2450|M.avium_104 WLGSIKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDEPSPHVDWSA
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 LIGSAKTNIGHLEAAAGIAGVIKVILSLENELLPQHRNFQNPSPHIPWDR
Mvan_0269|M.vanbaalenii_PYR-1 LIGSAKTNIGHLEAAAGIAGVIKVILSLEHRTLPKHLNFENPSPHIPWDR
Mflv_0405|M.gilvum_PYR-GCK LIGSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDR
MSMEG_0408|M.smegmatis_MC2_155 LIGSAKTNIGHLEAAAGIAGVIKVVMALENETLPKHLNFETPSPHIPWER
TH_4621|M.thermoresistible__bu -LTSVKTNFGHAESAAGALGMMKAILALQHGVVPQNLHFTRLPDEMAAIE
MMAR_0707|M.marinum_M LGLAVVEEFQEWP--AVVGRPRRAGVSSFGFGGTNAHVIVEQAVERVVER
Rv0405|M.tuberculosis_H37Rv LGLRVVDELQEWP--VVAGRPRRAGVSSFGFGGTNAHVIVEEAGS-----
Mb2074c|M.bovis_AF2122/97 GAVELLTAPRVWP---AGARTRRAGVSSFGISGTNAHVIIEAVPVVPRR-
MUL_2266|M.ulcerans_Agy99 GAVELLTEAQPWPAESAGDRVRRAGVSSFGISGTNAHVIVEAAPRVEVGG
MAV_2450|M.avium_104 GAVSLLTEAQPWP----GERPRRAGVSSFGISGTNAHVIIEAVPAVEPAH
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 LPVEVVREARPWGRN---GRPRIAGVSSFGFAGTNAHVILEEAPVVSRDA
Mvan_0269|M.vanbaalenii_PYR-1 LAVEVVKETIPWERD---GGPRIAGVSSFGFAGTNAHVILEEAP--EQAA
Mflv_0405|M.gilvum_PYR-GCK LPVEVVKESIPWRRGQRGGRPRIAGVSSFGFAGTNAHVILEEAP---LAA
MSMEG_0408|M.smegmatis_MC2_155 LPIEVVRETVPWQRN---GKPRIAGVSSFGFAGTNAHVILEEAPAVGTPA
TH_4621|M.thermoresistible__bu TNLFVPQATTLWPVR--EGCPRRAAVSSYGMSGTNVHAVLEQAPEPVQR-
MMAR_0707|M.marinum_M VVEVGPGVLAWV----VSARTAAGVGAQAGRLLEFVRAGRELDAGDVGYS
Rv0405|M.tuberculosis_H37Rv ---VG---------------------------------------------
Mb2074c|M.bovis_AF2122/97 EAGWAGPVVPWV----VSAKSESALRGQAARLAAYVRGDDGLDVADVGWS
MUL_2266|M.ulcerans_Agy99 SSGGAVPVVPWV----VSAKSGSALGAQAARLAAHVRSHDELDVADVGWS
MAV_2450|M.avium_104 ADAPALPVLPWV----VSAKSAAALRAQAARLAEYVRAQGELDIADVGWT
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 VEPPAPAGGRKFSILPLSARTPAALAQLADKYRAWLNAHPEAALADLCFT
Mvan_0269|M.vanbaalenii_PYR-1 APGPVQQPDRRFSLLPLSARTPAALTQLAGQYRDWWTAHPEATLADVCFT
Mflv_0405|M.gilvum_PYR-GCK EPAQESVDDGRFTLLPLSARTPAALMAVADRYRDWLVANPDATLADLCFT
MSMEG_0408|M.smegmatis_MC2_155 TTEPVE-DPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVSHT
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M LVTTRSLFEHRAVVVGAGRDELLAGLAEVVEGRPG-VGVASGVAMPGGKT
Rv0405|M.tuberculosis_H37Rv --------------------------ADTVSGRAD-VGGS----------
Mb2074c|M.bovis_AF2122/97 LAG-RSVFEHRAVVVGGDRDRLLAGLDELAGDQLG-GSVVRGTATAAGKT
MUL_2266|M.ulcerans_Agy99 LAG-RSTFEHRAVVLGADRDGLLAGLDELAGDEFGGASVIRGVAGAAGKT
MAV_2450|M.avium_104 LAG-RATFEHRAVVVGGDRDRLLAGLDELAADDPA-ASIIRGVATPAGKT
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 AGVGRAHLEHRAALVVNTREAAVELLSAVADDRPA-PGLGRGESHDTPKT
Mvan_0269|M.vanbaalenii_PYR-1 AGAGRAHLEHRAALVVNSAESAVELLGALADDRPA-PGLVRGESHDTPKT
Mflv_0405|M.gilvum_PYR-GCK AGTARSHLEHRAALVVNTREAALDLLGALADDRPA-PGLVRGESHDTPKT
MSMEG_0408|M.smegmatis_MC2_155 AGTARAHLEQRAALVVNSRESAIELLGALADDRPA-PGLVRGESHEAPKT
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M VFVFPGQGAQWLGMGRELCAGYPVFAAAFDAVVAELDRHLARPLREVVWG
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 VFVFPGQGSQWLGMGIELLDTAPAFAQQIDACAEAFAEFVDWSLVDVLRG
MUL_2266|M.ulcerans_Agy99 VFVFPGQGSQWIGMGIELLDTAPVFARHIESCGQAFAEFVDWSLLDVLRG
MAV_2450|M.avium_104 VFVFPGQGSQWLGMATELLDTAPVFAQHIQACEEAFAEFVDWSLIDALRG
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 AWLFTGQGSQYPGMARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFD
Mvan_0269|M.vanbaalenii_PYR-1 AWLFTGQGSQYPGMARELYDTEPVFAETLNRCAEAVADVLEKPLLDVIFD
Mflv_0405|M.gilvum_PYR-GCK AWLFTGQGSQYPGMSRELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFD
MSMEG_0408|M.smegmatis_MC2_155 AWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFD
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M AD-------AELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVG
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 AP------GAPGLDRVDVVQPVLFAVMVSLAELWKSVAVHPDAVIGHSQG
MUL_2266|M.ulcerans_Agy99 AA------GAPGLDRIDVVQPVLFAVMVSLAELWKSVGVRPDAVIGHSQG
MAV_2450|M.avium_104 AP------GAAGMDRVDVVQPALFAVMVSLAELWKSVGVSPDAVIGHSQG
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 VD---GPEAEETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVG
Mvan_0269|M.vanbaalenii_PYR-1 AE---ADDAEKTLQNTCYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVG
Mflv_0405|M.gilvum_PYR-GCK TDGVLDTDSNETLRHTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVG
MSMEG_0408|M.smegmatis_MC2_155 AD-ELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVG
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M ELSAAHVSGVLDLADAALLVVMRGRLMQALPGGGVMYAVQAGEQELRPLL
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 EIAAAYVAGALSLRDAARVVTLRSKLLAGLAGPGGMVSIACGADQARDLL
MUL_2266|M.ulcerans_Agy99 EIAAAYVAGALSLRDAAKVVTLRSKLLVGLAGPGGMVSVACGEQQARELL
MAV_2450|M.avium_104 EIAAAYVAGALSLRDAARVVTLRSKLLRSLAGPGGMLSIACSTERARELL
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 QYSAACVAEVFSLEDGARLIAERGRLFSSLPAGGRMAAVFTDAERAERLT
Mvan_0269|M.vanbaalenii_PYR-1 QYSAACVAGVFSLTDGARLMAERGRLFGSLPEGGRMVAVFTTAERAEAMT
Mflv_0405|M.gilvum_PYR-GCK QYAAACVAGVLSLRDGARLMAERGRLFGSLPSGGRMAAVFAAAERVEALT
MSMEG_0408|M.smegmatis_MC2_155 QYSAACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLT
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M G---EQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAF
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 APFGDRVSIAVVNGPSAVVVSGEVGALEELIAVCSTKELRTRRIEVDYAS
MUL_2266|M.ulcerans_Agy99 EPFGDRVSIAAINGPSAVVVSGEVAALEELIAQCADRELRTRRIDVDYAS
MAV_2450|M.avium_104 APYGNRVSIAAVNGRSAVVVSGEGAALDELAAFCADLALRTRRIDVDYAS
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 DEFPSLSVAAYNG--ANTVLSGPAQDLEKAIAALVADGVRCDFLETSHAF
Mvan_0269|M.vanbaalenii_PYR-1 DEFPSLSVAAYNG--TNTVLSGPAGDLEKAVATLSADGVRCDWLDTSHAF
Mflv_0405|M.gilvum_PYR-GCK DEYPALSVAAYNG--ANTVLSGPATDLERAVAGLVADGVRCDWLETSHAF
MSMEG_0408|M.smegmatis_MC2_155 DEYPSLSVAAYNG--ANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAF
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M HSVLMEPMLEQFRAVADEVYAGRPAIPVISNVTGQLV-AEDYGSADYWVR
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 HSVEVEAIRGPLAEALSGIEPRSTRTVFFSTVTGNRL-DTAGLDADYWYR
MUL_2266|M.ulcerans_Agy99 HSVEVEAIEGQLTEVLAGIEPLSSRTAFFSSVTGSRL-DTAELDAEYWYR
MAV_2450|M.avium_104 HSVEVEAIREDLAQALTGIEPRSSRIAFFSTVTGNRL-DTAGLDADYWYR
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 HSALLDPILDEFEAYANQFNYKTPQRILIDNRTGTALGRSVKLDGAYWRR
Mvan_0269|M.vanbaalenii_PYR-1 HSALLDPILDDFESYANQFDFAAPQRILIDNRTGTALGRSVQLDGTYWRR
Mflv_0405|M.gilvum_PYR-GCK HSALLDPILDDFESYARGITFTAPQRILIDNRTGAALGRSVTLDAAYWRR
MSMEG_0408|M.smegmatis_MC2_155 HSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRR
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M HIREAVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQ------VS
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 NVRQTVLFDQAVRNACEQGYRTFIESSPHPALITGVEETFAACTDGD-SE
MUL_2266|M.ulcerans_Agy99 NIRQTVQFDQAVRSACGHGYRTFIESSPHPALIAGIEDTYRNCAADSGAD
MAV_2450|M.avium_104 NIRQTVQFDQTVRSAAEHGYRTFIESSPHPALVAGIEDTVNDSLPGD-TE
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 HARQPVEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAWPDPATAP---
Mvan_0269|M.vanbaalenii_PYR-1 HARQPVEFAKSVRTLAEMNCKLLVEIGPRPVLTAAALGAWPDPATAP---
Mflv_0405|M.gilvum_PYR-GCK HARQPVEFAKSVHTLADMNCKLLVEIGPRPVLTAAALSAWPDPATSP---
MSMEG_0408|M.smegmatis_MC2_155 HARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTP---
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M VVAVPTLRKDRPEPFAVVGAVAQAFVRGAGVDWASVLAGCGGQRVGLPTY
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 AIVVPTLGRGDGGLHRFLLSAASAFVAGVAVNWRGTLDGAG--YVELPTY
MUL_2266|M.ulcerans_Agy99 PIVVPTLGREDGGLQRFLASAAAAFVAGVNVDWRGPLDGAG--LVELPTY
MAV_2450|M.avium_104 AIVIPTLGRDDGGLERFLTSAATAFVAGVNVAWRGVLDGAG--FVELPTY
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 -RAIASLRRNTADHRQITEAAADAYVLGHLPDFGAFQHAPAR-KLDLPTY
Mvan_0269|M.vanbaalenii_PYR-1 -RVIASLRRTAADHRQITEAVADAYVLGHLPEFGAFRDAGAR-KLDLPTY
Mflv_0405|M.gilvum_PYR-GCK -RVIASLRRTTADQRQITEAVADAYVLGHLPRFAAFRRDGAR-VLDLPTY
MSMEG_0408|M.smegmatis_MC2_155 -QVLASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDAR-KLDLPTY
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M AFAHERFWLADRFGVGQQVCVGQVLADEAGPGAHEAAGAAVGQGFAARLQ
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 AFDKRRFWLSAEGSGADVSGLGLGASEHPLLGAVVDLPASGGVVLTGRLS
MUL_2266|M.ulcerans_Agy99 AFEKRRFWLSGEGVSVDASGLGLSAGGHALLGAVVELPESGGVVLTGRLA
MAV_2450|M.avium_104 AFDRRRFWLSGEGAAADASGLGLGTSEHPLLSAVVELPASGGVVLTGRLS
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 PFERRQYWFSDKRDGDNRDAGNRQQNNGGPRTEAVRLLEDGKIEELANLL
Mvan_0269|M.vanbaalenii_PYR-1 PFEHRQYWFRDNQDPD----GSEALQPRTPSTEAVRLLEDGRIEELATLL
Mflv_0405|M.gilvum_PYR-GCK PFEHRQYWFSDSREPV------AAAPQRGARTETVRLLEDGRIEELAALL
MSMEG_0408|M.smegmatis_MC2_155 PFEHRQFWFSDNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALI
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M G-------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 PNVQPWLADHAVSDVVLFPGTGFVELAIRAGDEVGCSVLDELTLAAPLLL
MUL_2266|M.ulcerans_Agy99 LGAHGWLADHAVSGVVVFPGTGFVELAIRAVDEVGCSVVNELTLRTPLVL
MAV_2450|M.avium_104 PSLQGWLTDHAVSGTVVFPGAGFVELAIRAGDEVGCSTVEELTLQAPLML
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 GGVDGDQQTLNVLTKLAAQHN-----------------------------
Mvan_0269|M.vanbaalenii_PYR-1 DGAAGDQQTLDVLSRLAAQHN-----------------------------
Mflv_0405|M.gilvum_PYR-GCK GGTVDDPFTFDVLNRLAAQHN-----------------------------
MSMEG_0408|M.smegmatis_MC2_155 DGETVDEQTLRVLNKLAARHN-----------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 PAT----GSVAVQVVVDAGRDSNSRGVSIFSRADAQAG------WLLHAE
MUL_2266|M.ulcerans_Agy99 PAS----GSVAVQVVVGAAADSAERSVSIYSRTDTDTDTDAGSVWVCHAE
MAV_2450|M.avium_104 PAKDSGIGSVAVQVLVGEADESGRRDVSIFSRPDSDSP------WVCHAQ
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 GILRPGSVEPGADLSVWPPAGAVTVDVADGYERLATRGYRYGPAFRGLTA
MUL_2266|M.ulcerans_Agy99 GTLGADSAQPAADLSAWPPAGAIAVDVADGYERLDARGYGYGPAFRGLTA
MAV_2450|M.avium_104 GTLSTGSIEPGADLAAWPPAGATKVDIADGYQRLAARGYGYGPAFQGLTA
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 MWARGEEIFAEVRLPEAAGGVGGFGVHPALLDAVLHAVVI----AGDPDE
MUL_2266|M.ulcerans_Agy99 MWARGEELFAEARLPEAAGSTSGFGVHPALLDAALHTAVI----ANPDAD
MAV_2450|M.avium_104 AWVRGDEVFAEVRLPDAAGGVTGFGVHPALLDAAMHALIVGHQIAGDTDE
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 LALPFAWQGVSLHATGASAVRARIAPAGPS------AVSVELADGLGLPV
MUL_2266|M.ulcerans_Agy99 LVLPFSWQGVSLHAAGAASVRVRIAPVGPS------SVSVELADDLGLPV
MAV_2450|M.avium_104 VALPFAWQGVSLHAAGASAVRARLAPAQAPGTAASRAVSLELADGLGLPV
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 LSVASMVARPVTERQLLAAVSGSGPDRLFEVIWSPASAATSPGPTPAYQI
MUL_2266|M.ulcerans_Agy99 LSVKAMVARPVSEQQMRAVVSASGPDRLFEVVWTPMTVAAT-DAAPAYEL
MAV_2450|M.avium_104 LSVRAMVARSVSERQLRAAVSAAGPDRLFEVAWAPVTVPAAHGEPPVHQV
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --LQRTTQTIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVADAAGAAQPL
Mvan_0269|M.vanbaalenii_PYR-1 --QQRSSQSITNDRYEIRWEQSAAALSGAETDEVSSWILVGDDTEATRPL
Mflv_0405|M.gilvum_PYR-GCK --QQRSTESIADDRYQIRWETAAEPPVGADAADGITWLLVGDDTDATRPL
MSMEG_0408|M.smegmatis_MC2_155 --QQRSTHVDPDARYEIRWDAIAS--AAASTGAAADWILVGDDTAAVLEF
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 FESVAADQDPVAGSYVRSHQALAAVQSWLTDHESGVLVVATRGAMALPRE
MUL_2266|M.ulcerans_Agy99 FESIAADGDPLSGTYQRTHQALAAVQSWLTEHDSGVLVVATRGAMALAGE
MAV_2450|M.avium_104 FESLAAEGDPVGESYRRTHEALAAVQSWLTEHDSGVLVVVTRGAMALAGE
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 LDVLTARGQQHRVLALPVSDADEAELVEALRSAADEDSALRIVHVAALAG
Mvan_0269|M.vanbaalenii_PYR-1 VDVLSARGQRYRIFGLPVSDADEEQLGEALRLAAAEDSTLRIVHVGGLDS
Mflv_0405|M.gilvum_PYR-GCK VDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADATDLRIVHVAALDA
MSMEG_0408|M.smegmatis_MC2_155 ADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAG--ELYVVHIAAGDG
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 DVADLAGAAVWGLVRSAQTEHPGRIVLVDSDAATDDAAIAMALATGEPQV
MUL_2266|M.ulcerans_Agy99 DVTDLAGAAVWGLVRSAQTENPGRLVLVDSDAAVDAAAVATALAVGEPQV
MAV_2450|M.avium_104 DVTDLSGAAVWGLVRSAQTEHPGRIVLIDSDAALDDSALTAALATGEPQV
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 Q----GSSSAQSLLRIQHQVLGGTRRLFRAAAAAELRAPIWIVTRGAQHV
Mvan_0269|M.vanbaalenii_PYR-1 DPDPGTAPSMRSLLRMQHRILGGTRRLFRAAAAAELRTPIWVVTRRAQHV
Mflv_0405|M.gilvum_PYR-GCK A---ESDTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMWLVTRGAQHV
MSMEG_0408|M.smegmatis_MC2_155 A-----AAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIWLVTRDGQRV
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 VLRGGQVYTARVRGSRAADAILVPPGDGPWRLGLGSAGTFENLRLEPVPN
MUL_2266|M.ulcerans_Agy99 VLRNGQPYTARVHASRAADGILVPPVDGPWRLGLSSAGTFENLQLEPVPN
MAV_2450|M.avium_104 LLRDGTVYTARVHGSRAVDGIMTPPEDRPWRLGISSAGTFENLQLEPVPN
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 IEGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDAGTDEWAQFIGRVS
Mvan_0269|M.vanbaalenii_PYR-1 TATDTVAPDQSCLWGFGRAAALELPQLWGGLADLADGTADEWSRLLNRIT
Mflv_0405|M.gilvum_PYR-GCK TDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGGTSDEWSRLLNRIA
MSMEG_0408|M.smegmatis_MC2_155 TDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSG-ADTEWPRLIARIT
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 ADAPLGPGQVRVAMRAIAANFRDIMITLGMFTHDALLGGEGAGVVVEVGP
MUL_2266|M.ulcerans_Agy99 AGAPLGPGQVRVAMRAIAANFRDIMITLGMFTHDALIGGEGAGVVVEIGP
MAV_2450|M.avium_104 PDAALQPGQVRVALRAIATNFRDVMITLGMFTHDALLGGEGAGVVVEVGP
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 VSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVRSDA--------
Mvan_0269|M.vanbaalenii_PYR-1 APHGPAVREDQIALRDHAVYVPRLVRRAGRPAGKPLQLRDDA--------
Mflv_0405|M.gilvum_PYR-GCK ATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLRADA--------
MSMEG_0408|M.smegmatis_MC2_155 SPRD---GEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDR--------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 GVTEFSVGDSVFGFFPDGSGTLVAGDVRLLLPMPADWSYAEAAAISAVFT
MUL_2266|M.ulcerans_Agy99 EVTEFAVGDAVYGFFPDGSGTLVAGDVRLLLPKPADWSYAEAAAISAVFT
MAV_2450|M.avium_104 GVTEFSVGDSVYGFFPDGSGTLVPGDVRLLQHKPTHWSYPEAAGISAVFT
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 TAYYAFIHLADVQPGQRVLIHAGTGGVGMAAVQLARHLGLEVFATASKGK
MUL_2266|M.ulcerans_Agy99 TAYYAFVHLANVQPGQRVLVHAATGGVGMAAVQLARHLGLEVYATASKGK
MAV_2450|M.avium_104 TAYMAFIHLADVKPGQRVLVHAAAGGVGMAAVQLARHLGLEVFATASRGK
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 WDTLRAMGFDDDHISDSRSLEFEDKFRAATGGRGFDVVLDSLAGEFVDAS
MUL_2266|M.ulcerans_Agy99 WDILRAMGFDEDHISDSRSLEFEEKFREVTGGRSVDVVLDSLAGEFVDAS
MAV_2450|M.avium_104 WDTLRAMGFDDDHIGDSRTLEFEDKFRSATGGAGMDVVLDSLAGEFVDAS
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 LRLVAPGGVFLEMGKTDIRDPGVIAQQYPGVRYRAFDLFEAGPDRIAQIL
MUL_2266|M.ulcerans_Agy99 LRLLGPGGVFLEMGKTDIRDPGVIAQEYPGVRYRAFDLFEPGRPRMHQYM
MAV_2450|M.avium_104 LRLVAPGGVFLEMGKTDIRDPGVVAREYPGVRYRAFDLFEPGRPRMRQWM
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 AELATLFGDGVLRPLPVTTFDVRRAPAALRYLSQARHTGKVVMLMPG---
MUL_2266|M.ulcerans_Agy99 LDLAGLFDAGVLRPLPVTAFDVRRAPAALRYLSQARHVGKVVMTMPADQG
MAV_2450|M.avium_104 VELAGLFDAGVLNPLPVTTFDIRRGRAALRYLSQARHIGKVVMTVPG---
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_0269|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0405|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0408|M.smegmatis_MC2_155 --------------------------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 -SWAAGTVLITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAEL
MUL_2266|M.ulcerans_Agy99 GALGGGTVLITGGTGMAGSALARHLVAHHGVAHLVLISRRGPAAPGATEL
MAV_2450|M.avium_104 -ALSAGTVLITGGTGMAGSTLARHLVTGHGVRDLALLSRTGPDAPGAAEF
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 ------TYLVTGGLGSIGLEIAGYLAGRGAKHLVLTSRREPGEAARQRID
Mvan_0269|M.vanbaalenii_PYR-1 ------TYLVTGGLGSIGLEIAGYLAAHGARHLVLTSRRAPGDATQQRID
Mflv_0405|M.gilvum_PYR-GCK ------TYLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIE
MSMEG_0408|M.smegmatis_MC2_155 ------TYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPGDDARRRLD
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 VAELAAAGAQVQVVACDAADRAALAKVIADIPVQHPLSGVIHTAGALDDA
MUL_2266|M.ulcerans_Agy99 VAELSAAGAQVEVVACDAADRPALAKVIAENPAQRPLSAVVHAGGVLDDA
MAV_2450|M.avium_104 VAELEAAGARVQVIACDAADRAALAGVIAGISAERPLSGVIHAAGVLDDA
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 ALAAQG-CEVRAVTADVADGHDVARLLAGIQAELPPLAGIVHAAGEIGTT
Mvan_0269|M.vanbaalenii_PYR-1 ALGAQHSCQIRVVAADVADAHDVARLLAAVAAELPPLAGIVHAAGEIGTT
Mflv_0405|M.gilvum_PYR-GCK ALRERHGCEVRVVTADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGTT
MSMEG_0408|M.smegmatis_MC2_155 GLREQYACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTT
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 VVMSLTPDRVDVVLRSKVDAAWHLHELTRDLD--VSAFVMFSSMAGLVGS
MUL_2266|M.ulcerans_Agy99 VISSLTPERVDTVLRAKVDAAWNLHELTRDLD--LSAFVMFSSMAGVVGS
MAV_2450|M.avium_104 MITSLTPERIDAVLRAKVDAAWNLHELTRDMN--LSAFVMFSSMAGLVGS
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 PLSDLEDAEVDRVFAGKVWGAWHLSEAAAGLK--LDFFINTSSIAAVWGG
Mvan_0269|M.vanbaalenii_PYR-1 PLVSLEDSEVDRVFAGKVWGAWHLSEAAADLQ--LDFFLGTSSIASVWGG
Mflv_0405|M.gilvum_PYR-GCK PLADLDDAEVDRVFAGKVWGAWHLSEATSDLQ--LDFFISTSSIASVWGG
MSMEG_0408|M.smegmatis_MC2_155 PLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGG
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M ------------------------LSDAEQQAAVLAMVCEHTAAVLGRDG
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 SGQANYAAANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTSGLDAADL
MUL_2266|M.ulcerans_Agy99 SGQANYAAANTFVDGLAAHRRAHGLPAISLGWGLWDQASDMTGGMDAADR
MAV_2450|M.avium_104 SGQGNYAAANSFLDALAAHRRAHGLPAISLAWGLWDQASAMTGGLDAADL
MLBr_00135|M.leprae_Br4923 ----------------------------------------MTASVEGADQ
MAB_0939|M.abscessus_ATCC_1997 YGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAESRARLEQ
Mvan_0269|M.vanbaalenii_PYR-1 YGQTAYGAANAFLDGLAWRLREQGISGVSINFGPWSAGMADAESRARLDQ
Mflv_0405|M.gilvum_PYR-GCK FGQAAYGAANAFLDGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLEQ
MSMEG_0408|M.smegmatis_MC2_155 FGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQ
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M A-------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 ARLGREGVLALSTAEALELFDTAM-IVDEPFLAPARIDLTALRAHAVAVP
MUL_2266|M.ulcerans_Agy99 ARLGREGVLALSSDEAMELFDTAL-IVNQAFLAPARIDLAALRAHAVAVP
MAV_2450|M.avium_104 ARLGRDGILALSSDEAMELFDTAL-IVDEPFLAPARIDLGALRAHAVAVP
MLBr_00135|M.leprae_Br4923 K-------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 RGIKTLSPTDALAGLADVVAASGS-NAVQGVIARIDWARFLPLYQQAGKR
Mvan_0269|M.vanbaalenii_PYR-1 RGVRTLSPADALAGLADVVTAAEAPGPAQGIVARIDWERFLPLYQQAGRR
Mflv_0405|M.gilvum_PYR-GCK RGIKTLSPADALAGLSDAVISAAP----HPVVARVDWSRFLPLYQQAGRR
MSMEG_0408|M.smegmatis_MC2_155 RGVRTLSPAEALAGMADVVAGPVQ-----GVVAKIDWSRFLPLYQQAGRR
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 PMFSDLASAPTRRQVDDSVAAAKSKSALAHRLHGLPEAEQHAVLLGLVRL
MUL_2266|M.ulcerans_Agy99 PMFSDLVSAPTRRQIDAALATAKSKSALAHRLHGLPELEQHAVVLDLVRS
MAV_2450|M.avium_104 PMFADLVNAPTRRRVDDSLAAAKSKSALAHRLDGLPEAEQHAVLLELVRS
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 GFLAELDREVPSHLAGV--AGAQSGSTQLVERLANAPVQQRKKLLTDYLR
Mvan_0269|M.vanbaalenii_PYR-1 AFLAELEREVPDTAP----AATPSGRTELVERLTNAPVQQRKKLLTDYLR
Mflv_0405|M.gilvum_PYR-GCK GFLAELERELPAAPAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLR
MSMEG_0408|M.smegmatis_MC2_155 AFLSELESELPAAATGAAAPATVPGKPPLVEQLTKAPVQQRKSLITNYLR
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M -----------AQLDAGQAFSDAGLTSLSAVELRNRLKTLTGVTLSATTA
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 HIATVLGNITPEAIDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLI
MUL_2266|M.ulcerans_Agy99 HIATVLGTITPEAIDPDKAFQELGFDSLTAVEMRNRIKTVTGLSLSPTLI
MAV_2450|M.avium_104 HIATVLGSPTAEAIDPDKAFQELGFDSLTAVEMRNRLKTATGLALSPTLI
MLBr_00135|M.leprae_Br4923 --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997 DAVAEVTRVDVSEIREDAGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLV
Mvan_0269|M.vanbaalenii_PYR-1 TAVAEITRVDATEIREDAGFFDLGMDSLMAVELRRRIEQGVGREIPATLA
Mflv_0405|M.gilvum_PYR-GCK DAVAEVTRVDAAEIREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLV
MSMEG_0408|M.smegmatis_MC2_155 NAVAEVTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLV
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M FDYPTPTQLADHLLSHLHHQNRSA-----PAAAVRTRVRIDEPIAIVGMG
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 FDYPTPNRLASYIRTELAGLPQEI-----KHTP-AVRTTSEDPIAIVGMA
MUL_2266|M.ulcerans_Agy99 FDYPTPNGLANYIRAELAGAPQEV-----KHTP-AVRVTGDDPIAIVGMS
MAV_2450|M.avium_104 FDYPTPNALAGYIRTELAGAPQET-----THAP-VVRATDDDPIAIVGMS
MLBr_00135|M.leprae_Br4923 -----SEKLISYLKKVVVELDETR-----ARLR-EYEQRATEPVAVVGIG
MAB_0939|M.abscessus_ATCC_1997 MDHPRISDVADYLLGDVLGLAEQA--KPAAQLASAVTGRTDEPIAIVAVS
Mvan_0269|M.vanbaalenii_PYR-1 MDHPRLSDVADYLLGEVLGLAEQAPAKAGSQPASAAANRTDEPIAIVAVS
Mflv_0405|M.gilvum_PYR-GCK MDHPRLSDAADYLLGDVLGLTEAA---TAPKAATVVSTAADEPIAIVAVS
MSMEG_0408|M.smegmatis_MC2_155 MDHPRLSDAADYLLVEVLGLGEQT----NVRQASTVTARTDDPIAVVAVS
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M CRYPGGVSSPAQLWQLVASGGDVIGEFPPDRGWDIERLFDPDPDALGKTY
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 CRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAGLYNPDPDAAGACY
MUL_2266|M.ulcerans_Agy99 CRYPGGIESPDDLWDMLMARRDVLSDFPADRGWDLAGLFNPDPDVPGACY
MAV_2450|M.avium_104 CRFPGGVDSPEALWQMVAEGRDVLSEFPTDRGWDLAGVYNPDPDVPGTCY
MLBr_00135|M.leprae_Br4923 CRFPGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKTY
MAB_0939|M.abscessus_ATCC_1997 CRFPG-APDPEAFWDVLSGGVDAIREVPEDR-FDIDEFYDPDPEVAGKTY
Mvan_0269|M.vanbaalenii_PYR-1 CRFPG-APDPEAFWEVLAGGVDAIREVPEDR-FDIDEFYDPDPDAAGKTY
Mflv_0405|M.gilvum_PYR-GCK CRFPG-APNPEAFWDLLSGGVDAIREVPEDR-FDIDEFYDPDPDAAGKTY
MSMEG_0408|M.smegmatis_MC2_155 CRFPG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKTY
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M TRHGGFVSDVADFDPGFFGISPGEALAMDPQQRLLLETSWEALEDAGIDP
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 TRTGGFVDGVGDFDPAFFGVGPSEALAMDPQQRMLLELSWEALERAGIDP
MUL_2266|M.ulcerans_Agy99 TRTGGFVDRVGDFEPAFFGVGPSEALAMDPQQRMFLELSWEALERAGIEP
MAV_2450|M.avium_104 TRTGGFVDNVADFDPAFFGIAPSEALAMDPQQRMFLELSWEALERAGIDP
MLBr_00135|M.leprae_Br4923 TRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGIDP
MAB_0939|M.abscessus_ATCC_1997 TRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYSP
Mvan_0269|M.vanbaalenii_PYR-1 TRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGLAP
Mflv_0405|M.gilvum_PYR-GCK TRYGGFLDHIDEFDPEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYAP
MSMEG_0408|M.smegmatis_MC2_155 TRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAP
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M QALRGSSTGVFVGIYGDGYGL-GTSQ----AQWYADTGHITSVASGRISY
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 TGLRGSATGVFAGVMTQGYGMFAAEP----VEGFRLTGQLSSVASGRVAY
MUL_2266|M.ulcerans_Agy99 GGLRGSATGVFAGVMTQGYGMFAAEP----VEGFRLTGQLSSVASGRVAY
MAV_2450|M.avium_104 VKLRGSATGMFAGVYTQGYGMGAAPI----AEGFRLTGQSSSVASGRVSY
MLBr_00135|M.leprae_Br4923 LSLRGSATGVFTGIFAPSYGSRDTGG----LQGYGLTGTAVSVASGRVSY
MAB_0939|M.abscessus_ATCC_1997 AALRGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVAF
Mvan_0269|M.vanbaalenii_PYR-1 ADLRGSRTGIFVGVAANEYAHLLSSESIEKIEPHFITGNALNAISGRVAF
Mflv_0405|M.gilvum_PYR-GCK SALRGSRTGVFVGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAF
MSMEG_0408|M.smegmatis_MC2_155 SDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAF
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M CLGLAGPAISVDTACSSSLVALHLAANSLRAGECDLALAGGSTVLATPSI
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 VLGLEGPAVSVDTACSSSLVALHMAVGSLRSGECDLALAGGVTVNATPDI
MUL_2266|M.ulcerans_Agy99 VLGLEGPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGVTINATPDI
MAV_2450|M.avium_104 VLGLEGPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGVTVNATPDI
MLBr_00135|M.leprae_Br4923 VLGLEGPAVSVDTACSSSLVAIHWAMSSLRSGECDLALAGGVTVMGLPSI
MAB_0939|M.abscessus_ATCC_1997 ALGFEGPAVAVDTACSSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVT
Mvan_0269|M.vanbaalenii_PYR-1 ALGLEGPAVAVDTACSSALVAVHQACQALHSGDCDLALAGGVNVLLSPVT
Mflv_0405|M.gilvum_PYR-GCK ALGLEGPAVAVDTACSSSLVAVHQATQALRSGDCDMALAGGVNVLLSPVT
MSMEG_0408|M.smegmatis_MC2_155 ALGFEGPAVAVDTACSSALVAVHQACQALQSGDCDLALAGGVNVLLSPVT
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M FIGFSRQRGLATDGRCKAFADAADGTGFSEGAGMLVLQRLSDARRAGQPV
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 FVEFSRWRGLSPDGRCKAFAAAADGTGFSEGGGMLVLQRLSDARRLGHPV
MUL_2266|M.ulcerans_Agy99 FVEFSRWRGLSADGRCKAFAGAADGTGFSEGGGMLVVERLSDAQRLGHPV
MAV_2450|M.avium_104 FVEFSRMRGLSVDGRCKAYAGAADGTGFSEGGGMLVVERLSDARRLGHPV
MLBr_00135|M.leprae_Br4923 FVGFSRQRGLAADGRCKAFARAADGTGWGEGAGVVVLERLSDAQRLGHTV
MAB_0939|M.abscessus_ATCC_1997 VIAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAERDGDRV
Mvan_0269|M.vanbaalenii_PYR-1 SVAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLGDAVRDGDRV
Mflv_0405|M.gilvum_PYR-GCK VVAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVRDGDRV
MSMEG_0408|M.smegmatis_MC2_155 VVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDRV
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M LAILAGSAVNQDGASNGLTAPSGPAQQRVISAALSDAGITGADVDVVEAH
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 LAVVVGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGH
MUL_2266|M.ulcerans_Agy99 LALVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGH
MAV_2450|M.avium_104 LAVVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGH
MLBr_00135|M.leprae_Br4923 LAVVRGSAVNQDGASNGLTAPNGLAQQRVIQAALTNAGLSSADVDVVEAH
MAB_0939|M.abscessus_ATCC_1997 LAVIPGSAVNQDGASSGLTVPNGGAQQRLIGSVLARAGLVGGDVDYLEAH
Mvan_0269|M.vanbaalenii_PYR-1 CAVIPSSAVNQDGASSGLTVPNGGAQQRLIGMALARAGLSGGDVDYLEAH
Mflv_0405|M.gilvum_PYR-GCK CAVIAGSAVNQDGASSGLTVPNGGAQQRLIGTVLARAGITGGEVDYLEAH
MSMEG_0408|M.smegmatis_MC2_155 CAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADVDYLEAH
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M GTGTRLGDPIEAQALLATYGRDHTPD----APLWLGSIKSNMGHSQAAAG
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 GTGTTLGDPIEAQALLATYGQDRGEP---GEPLWLGSVKSNMGHTQAAAG
MUL_2266|M.ulcerans_Agy99 GTGTTLGDPIEAQALLATYGQDRGSAGAAGKALWLGSIKSNMGHTQAAAG
MAV_2450|M.avium_104 GTGTTLGDPIEAQALLATYGQDRGQP------LWLGSIKSNMGHTQAAAG
MLBr_00135|M.leprae_Br4923 GTATTLGDPIEAQALLATYGQGRPAD----QPLWVGSIKSNMGHTQAAAG
MAB_0939|M.abscessus_ATCC_1997 GTGTPLGDPIEVQAAAAAYGGSRDADR----PLLMGSVKSNIGHTESASG
Mvan_0269|M.vanbaalenii_PYR-1 GTGTPLGDPIEVQAAAAAYGASRDADR----PLLMGSVKTNIGHLESASG
Mflv_0405|M.gilvum_PYR-GCK GTGTPLGDPIEVQAAAAAYAGARDADR----PLLMGSVKTNIGHTESASG
MSMEG_0408|M.smegmatis_MC2_155 GTGTPLGDPIEVQAAAAAYGAGRDADR----PLLMGSVKTNIGHTESASG
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M VAGVIKMVEAMRHQLLPATLHIDQPSAHVDWSPGTVQLLTEAREWPA--V
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 VAGVIKMVLAMRHELLPATLHVDVPSPHVDWSAGAVELLTAPRVWP---A
MUL_2266|M.ulcerans_Agy99 VAGVIKMVQAMRHEVLPATLHVDVPSPHVDWSAGAVELLTEAQPWPAESA
MAV_2450|M.avium_104 VAGVIKMVLAMRHELLPATLHVDEPSPHVDWSAGAVSLLTEAQPWP----
MLBr_00135|M.leprae_Br4923 VAGVIKMVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDWS---V
MAB_0939|M.abscessus_ATCC_1997 AAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQA---
Mvan_0269|M.vanbaalenii_PYR-1 AAGLIKVVLSLQHNLLPQSLHFENPSPHIPWDSLPVRVVDKAIPWQA---
Mflv_0405|M.gilvum_PYR-GCK AAGLIKVVLSLQHETLPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQP---
MSMEG_0408|M.smegmatis_MC2_155 AAGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQT---
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M VGRPRRAGVSSFGVSGTNAHVIVEQAV---------------ERVVERVV
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 GARTRRAGVSSFGISGTNAHVIIEAVP---------------VVPRR-EA
MUL_2266|M.ulcerans_Agy99 GDRVRRAGVSSFGISGTNAHVIVEAAP---------------RVEVGGSS
MAV_2450|M.avium_104 GERPRRAGVSSFGISGTNAHVIIEAVP---------------AVEPAHAD
MLBr_00135|M.leprae_Br4923 EGRPRRAGVSSFGISGTNAHVILEEAPTP------------VEASYSTAD
MAB_0939|M.abscessus_ATCC_1997 NGRPRRAGVSSFGFTGTNAHVLIEEAPQPQATP----------DEDDAST
Mvan_0269|M.vanbaalenii_PYR-1 DGRPRRAGVSSFGFTGTNAHVLIEEAPLPQAAD----------PVEEPDT
Mflv_0405|M.gilvum_PYR-GCK NGRPRRAGVSSFGFTGTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAAD
MSMEG_0408|M.smegmatis_MC2_155 NGRVRRAGVSSFGFTGTNAHVLVEEAPPQLHTADAAP----VEPAATAEA
TH_4621|M.thermoresistible__bu --------------------------------------------PEESAD
MMAR_0707|M.marinum_M EVGPGVLAWVVSARTAAGVGAQAGRLLEFVRAG-RELDAGDVGYSLVTTR
Rv0405|M.tuberculosis_H37Rv --GGGVVAWVISGKTASALAAQAGRLGRYVRAR-PALDVVDVGYSLVSTR
Mb2074c|M.bovis_AF2122/97 GWAGPVVPWVVSAKSESALRGQAARLAAYVRGD-DGLDVADVGWSLAG-R
MUL_2266|M.ulcerans_Agy99 GGAVPVVPWVVSAKSGSALGAQAARLAAHVRSH-DELDVADVGWSLAG-R
MAV_2450|M.avium_104 APALPVLPWVVSAKSAAALRAQAARLAEYVRAQ-GELDIADVGWTLAG-R
MLBr_00135|M.leprae_Br4923 QQRLSVVPWVVSGRSTAALMAQASRLAFYVQAD-PEVDPVDVGCALAA-R
MAB_0939|M.abscessus_ATCC_1997 PQSAPVSVLPLSARSPEALAAVAQRYESWLAAH-PDVDLEDVCLTAGRGR
Mvan_0269|M.vanbaalenii_PYR-1 -RALPVGVLALSARSPEALTALAQRYEAWLSAH-PDADLADVCRTAGTGR
Mflv_0405|M.gilvum_PYR-GCK PAPAPVEVLPLSARSPEALVALAQRYETWLTAH-PEADLADVCRTAGTGR
MSMEG_0408|M.smegmatis_MC2_155 GTDDSPQVLALSARSPEALVELARRYDDWLSAT-PGLDIADVCHTAGVGR
TH_4621|M.thermoresistible__bu TDAAGPLVFALSSTSAEELRRTAGRLAEWVEAHTDEVVPADLAYTLARRR
:*. : : * * : . *: : *
MMAR_0707|M.marinum_M SLFEHRAVVVGAGRDELLAGLAEVVEGRPG-VGVASGVAMPGGKTVFVFP
Rv0405|M.tuberculosis_H37Rv SVFDHRAVVVGQTRDELLAGLAGVVAGRPE-AGVVCGVGKPAGKTAFVFA
Mb2074c|M.bovis_AF2122/97 SVFEHRAVVVGGDRDRLLAGLDELAGDQLG-GSVVRGTATAAGKTVFVFP
MUL_2266|M.ulcerans_Agy99 STFEHRAVVLGADRDGLLAGLDELAGDEFGGASVIRGVAGAAGKTVFVFP
MAV_2450|M.avium_104 ATFEHRAVVVGGDRDRLLAGLDELAADDPA-ASIIRGVATPAGKTVFVFP
MLBr_00135|M.leprae_Br4923 SVFEHRAVVVGESREQLIAGLAGLAVGESG-AGVAIGQAAPLGKTVVVFP
MAB_0939|M.abscessus_ATCC_1997 SHFEHRAALVVDSIQTAREGLLELAQNRLR-PGVVRGEHTNHPTTAWLFT
Mvan_0269|M.vanbaalenii_PYR-1 SHFEHRAALVVDSVAAAREGLAELAQNRLR-PGVVRGEHTHHPTTAWLFT
Mflv_0405|M.gilvum_PYR-GCK SHFEHRAALVVDSVESARIALTDLAQNRLR-PGVVRGEHLNHPTTAWMFT
MSMEG_0408|M.smegmatis_MC2_155 SHFEYRAALVVDSVERAREGLAALAEGRTP-AGVVRGEHVHRPTTAWLFT
TH_4621|M.thermoresistible__bu AHRPVRTTVIADGVEALTAGLREVADGDAP---YQPAVGMDDKAPVWVFS
: *:.:: .* :. . . .. :*.
MMAR_0707|M.marinum_M GQGAQWLGMGRELCAGYPVFAAAFDAVVAELDRHLARPLREVVWGAD---
Rv0405|M.tuberculosis_H37Rv GQGSQWLGMGSELYAAYPVFAEALDAVVDELDRHLRYPLRDVIWGHD---
Mb2074c|M.bovis_AF2122/97 GQGSQWLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVMWGHD---
MUL_2266|M.ulcerans_Agy99 GQGSQLLGMGMGLHAGYPVFAEAFNTVVGELDRHLLRPLREVIWGHD---
MAV_2450|M.avium_104 GQGSQTLGMGRQLHAGYPVFAEAFDAVVAELDRHLLRPLRDVIWGDD---
MLBr_00135|M.leprae_Br4923 GQGAQRIGMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGAD---
MAB_0939|M.abscessus_ATCC_1997 GQGSQYPGMARELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRET
Mvan_0269|M.vanbaalenii_PYR-1 GQGSQFPGMARELFETEPVFADAVTRCADAVKDILPRPLLEVLFAADRES
Mflv_0405|M.gilvum_PYR-GCK GQGSQYPGMARELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREA
MSMEG_0408|M.smegmatis_MC2_155 GQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRET
TH_4621|M.thermoresistible__bu GQGSQWAGMGAELLATEQVFAAKIAEIEPLVARESGFSVTEAMTASET--
***:* **. * *** . : .: :.: .
MMAR_0707|M.marinum_M ----AELLNTTEFAQPALFAVEVALYRLLESWGMRPGLVMGHSVGELSAA
Rv0405|M.tuberculosis_H37Rv ----QDLLNTTEFAQPALFAVEVALYRLLMSWGVRPGLVLGHSVGELAAA
Mb2074c|M.bovis_AF2122/97 ----ENLLNSTEFAQPALFAVEVALFRLLGSWGVRPDFVMGHSIGELSAA
MUL_2266|M.ulcerans_Agy99 ----ENLLNTTEFAQPALFAVEVALYRLLESWGVRPDFVMGHSVGELSAA
MAV_2450|M.avium_104 ----ENVLNSTEFAQPALFAVEVALFRLLESWGVRPDFVMGHSIGELSAA
MLBr_00135|M.leprae_Br4923 ----AGLLDSTEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAA
MAB_0939|M.abscessus_ATCC_1997 GGKAGEALRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAA
Mvan_0269|M.vanbaalenii_PYR-1 G----EALRHTSFAQPAIFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAA
Mflv_0405|M.gilvum_PYR-GCK GVPPTETLRHTSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAA
MSMEG_0408|M.smegmatis_MC2_155 A----DLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAA
TH_4621|M.thermoresistible__bu -------VTGIDRVQPTLFAIQVALAATMQSYGVRPGAVIGHSLGEVAAA
: . .**::**:::.* :.: *. *:***:*: :**
MMAR_0707|M.marinum_M HVSGVLDLADAALLVVMRGRLMQALPGGGVMYAVQAGEQELRPLLG----
Rv0405|M.tuberculosis_H37Rv HVAGALCLPDAAMLVAARGRLMQALPAGGAMFAVQAREDEVAPMLG----
Mb2074c|M.bovis_AF2122/97 HVAGVLSLENAAVLVAARGRLMQALPAGGAMVAVQAAEEEVRPLLS----
MUL_2266|M.ulcerans_Agy99 HVAGVLSLENAAVLVAARGRLMQALPDGGAMIAVQATEQEVLPLLG----
MAV_2450|M.avium_104 HVAGVLSLQNAAVLVAARGRFMQALPEGGAMIAVQATEAQVRPLLG----
MLBr_00135|M.leprae_Br4923 YVAGVLAPADAAMLVVARGRLMQSMPAGGTMWAVAASEDEVVSLLG----
MAB_0939|M.abscessus_ATCC_1997 CVAGVFSIEDGARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEF--
Mvan_0269|M.vanbaalenii_PYR-1 CVAGVFSLEDGARLMAERGRMFGSLPEGGRMVAVFTDAKLVEEIAGDF--
Mflv_0405|M.gilvum_PYR-GCK CVAGVFSLEDGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAADF--
MSMEG_0408|M.smegmatis_MC2_155 CVAGVFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEF--
TH_4621|M.thermoresistible__bu VVAGALSLEDGVKVICRRSRLCLRLAGAGAMAAIELPAQAVREFLAARGV
*:*.: :.. :: *.*: :. .* * *: : . .
MMAR_0707|M.marinum_M EQVSVAAVNGPGSVVLSGAREAVSVVVDRLAAQGRRVRRLAVSHAFHSVL
Rv0405|M.tuberculosis_H37Rv HDVSIAAVNGPASVVISGAHDAVSAIADRLRGQGRRVHRLAVSHAFHSAL
Mb2074c|M.bovis_AF2122/97 AEVDIAAVNGPASLVISGAQNAVAAVADQLRADGRRVHQLAVSHAFHSPL
MUL_2266|M.ulcerans_Agy99 AQVSIATINGPASVVISGAQDAVSAVAEQLRADGRRVHRLAVSHAFHSPL
MAV_2450|M.avium_104 PDVGIAAVNGPAAVVISGDHDAAVAIAERLRAEGHRVHRLSVSHAFHSPL
MLBr_00135|M.leprae_Br4923 EGVGIAAINAPESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPL
MAB_0939|M.abscessus_ATCC_1997 PRVSVGAYNGP-NTVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSEL
Mvan_0269|M.vanbaalenii_PYR-1 PRVSVGAYNGP-NTVLSGPGEDLEQIVDRFGDDGVRCTWLQTSHAFHSEL
Mflv_0405|M.gilvum_PYR-GCK PRVSVGAYNGP-NTVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSEL
MSMEG_0408|M.smegmatis_MC2_155 PRVSVGAYNGP-NTVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSEL
TH_4621|M.thermoresistible__bu DDVVLSVIASPESTVIGGATDTVRELVAAWEAQGVMAREVAVDVASHSPQ
* :.. .* *:.* . :* : .. * **
MMAR_0707|M.marinum_M MEPMLEQFRAVADEVYAGRPAIPVISNVTG-QLVAEDYGSADYWVRHIRE
Rv0405|M.tuberculosis_H37Rv MEPMIAEFTAVAAELSVGLPTIPVISNVTG-QLVADDFASADYWARHIRA
Mb2074c|M.bovis_AF2122/97 MDPMIDEFAAVAAGIAIGRPTIGVISNVTG-QLAGDDFGSAAYWRRHIRQ
MUL_2266|M.ulcerans_Agy99 MDPMIDEFATVAGELTVNAPTIGIISNLTG-QLAGEDFGSAAYWKRHVRD
MAV_2450|M.avium_104 MEPMIDEFGTVAAGLAIDKPVIPIISNLTG-QPAADDFGSPEYWKCHVRD
MLBr_00135|M.leprae_Br4923 MEPMLEEFVRVAAQVEVRKPQIGLVSNVTG-ELAGPDFGSPQYWGEHVSR
MAB_0939|M.abscessus_ATCC_1997 LDPILDEFESYAAQVQFAAPTLPLVCNRTGAVLTAQTPIDGQYWRRHSRQ
Mvan_0269|M.vanbaalenii_PYR-1 LDPVLDEFESYAAQFQFATPTLPLVCNRTGTVLTAQTPLDAQYWRRHSRQ
Mflv_0405|M.gilvum_PYR-GCK LDPVLDEFESYAAQLQFAAPTLPLVCNRTGAVLTGQTSLDAQYWRRHSRQ
MSMEG_0408|M.smegmatis_MC2_155 LDPVLDEFEAYAAQFQFAAPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQ
TH_4621|M.thermoresistible__bu VDPILDELEEILADLQPMTPTVPYYS-ATSYDPREKPVCDADYWVDNLRH
::*:: :: . * : . *. . ** :
MMAR_0707|M.marinum_M AVRFADSVCFAHSAGATRFVEVGPAGGLTSLIEESLAQVSVV----AVPT
Rv0405|M.tuberculosis_H37Rv VVRFGDSVRSAHCAGASRFIEVGPGGGLTSLIEASLADAQIV----SVPT
Mb2074c|M.bovis_AF2122/97 AVRFADSVRFAQAAGGSRFLEVGPSGGLVASIEESLPDVAVT----TMSA
MUL_2266|M.ulcerans_Agy99 AVRFADSIRFAQSAGAARFLEVGPSIGLTASIEEVLSDAAVTNPVATASA
MAV_2450|M.avium_104 AVRFADSVRFAQSAGATRFLEVGPSSGLTAAIEETLADAPVV----TVSA
MLBr_00135|M.leprae_Br4923 AVRFVDSARHLQTLGATHFIESGPSSGLMGAIEQSLAPAEAV----VVSM
MAB_0939|M.abscessus_ATCC_1997 PVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPR--AIVS
Mvan_0269|M.vanbaalenii_PYR-1 PVQFAESVRTVAALGCSVLMEIGPQPVLTGSAVQVWPEHLAAPR--AIVS
Mflv_0405|M.gilvum_PYR-GCK PVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPR--AIAS
MSMEG_0408|M.smegmatis_MC2_155 PVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPR--AVAS
TH_4621|M.thermoresistible__bu EVRFAAAVQAALEDGFRVFGELSPHPLLTRAVEQTARGLDMPVA--ALPA
*:* : * : * .* *
MMAR_0707|M.marinum_M LRKDRPEPFAVVGAVAQAFVRGAGVDWASVLAGCGGQRVGLPTYAFAHER
Rv0405|M.tuberculosis_H37Rv LRKDRPEPVSVMTAAAQGFVSGMGLDWASVFSGYRPKRVELPTYAFQHQK
Mb2074c|M.bovis_AF2122/97 LRKDRPEPATLTNAVAQGFVTGMDLDWRAVVG--EAQFVELPTYAFQRRR
MUL_2266|M.ulcerans_Agy99 LRKDRPEPVSLVSALAGVFVAGTAVDWRAVVG--QSHFVELPTYAFERRR
MAV_2450|M.avium_104 LRKDRPEPVALVNAVAQGWVCGMDVDWRGALG--TGHLVDLPTYAFDRRR
MLBr_00135|M.leprae_Br4923 MGKDRPELASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRR
MAB_0939|M.abscessus_ATCC_1997 LRKGVEDRRQIADALASAYVSGHRPNFAALQR-HPRRTVELPTYPFQRRR
Mvan_0269|M.vanbaalenii_PYR-1 LRKGVSDRRQITEALAAAYVGGHRPDFGALYR-RPGRAVALPTYPFQRRR
Mflv_0405|M.gilvum_PYR-GCK LRKGVADRRQIADALAAAYIGGHKPDFAALHE-QRGVRLELPTYPFQRRR
MSMEG_0408|M.smegmatis_MC2_155 LRKGVADRRQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRR
TH_4621|M.thermoresistible__bu MRREQEMPHGVRTMVGDLFAAGAAVDFAALYP--SGRLVDAPLPTWTRRK
: : : . : * :: . : * .: :.:
MMAR_0707|M.marinum_M FWLADRFGVGQQVCVGQVLADEAGPGAHEAAGAAVGQGFAAR--------
Rv0405|M.tuberculosis_H37Rv FWLAPAPSVSDPTAAGQIGASDGG------AELLASSGFAAR--------
Mb2074c|M.bovis_AF2122/97 FWLS-GDGVAADAASLGLAASEHALLG-AVIDLPASGGVVLTGRLSPSVQ
MUL_2266|M.ulcerans_Agy99 FWLS-GDAVPADAAGLGLQAGEHALLG-AVVELPASGGVVLTGRLSLAAQ
MAV_2450|M.avium_104 FWLS-GDGAASDAAGLGLAAGDHALLG-AVVELPASGGVLLTGRLSPASQ
MLBr_00135|M.leprae_Br4923 FWETPGTDGTASVSGLGLGSTEHALLG-AVVERPDSGGVVLTGRLSLANQ
MAB_0939|M.abscessus_ATCC_1997 FWPK-----SSGTAIEGGGGLPSG--ILGRGEDLASGDSVYISRLSVRSQ
Mvan_0269|M.vanbaalenii_PYR-1 FWPK-----TSGITTDG--PAVSG--ILGSAKDLASGDTVYTSRWSVRSQ
Mflv_0405|M.gilvum_PYR-GCK FWPK-----SAGMAIDGRVGASAGSGILGSGKDLASGDSVYTSRLSVKTQ
MSMEG_0408|M.smegmatis_MC2_155 FWPK-----ASSIAVDGG-TAASG--ILGSGKDLASGDTIYTSRLSVKSQ
TH_4621|M.thermoresistible__bu LVLS--RENGEQQTRGGCTITVHPLLGTHVRLPEEPERHVWQADLGTGAQ
:
MMAR_0707|M.marinum_M ---------------------LQGLSDAEQQAAVLAMVCEHTAAVLGRDG
Rv0405|M.tuberculosis_H37Rv ---------------------LAGRSADEQLAAAIEVVCEHAAAVLGRDG
Mb2074c|M.bovis_AF2122/97 GWLADHSVAGVTIFPGAGFVELAIRAGDEVGCGVVDELTLAAPLVLPASG
MUL_2266|M.ulcerans_Agy99 GWLADHAVGGVVIFPGAGFVELAIRAGDEVGCRVVDELTLAAPLVLPSGG
MAV_2450|M.avium_104 GWLADHAVGGVVLFPGAGFVELAIRAGDEVGCGIIDELNLAAPLVLPAGG
MLBr_00135|M.leprae_Br4923 PWLADHVIGGVVLFPGAGFVELVIRAGDEVGCAGVEELVLAAPLVLHPGS
MAB_0939|M.abscessus_ATCC_1997 PWLSDHVIYGTVVVPGATYAAMALAAVGTP--ARAKDVFFYEPIILPEKS
Mvan_0269|M.vanbaalenii_PYR-1 PWLADHVIYGTVVVPGATYAAMALAAVGTP--ARVKDVFFYEPIILPEKA
Mflv_0405|M.gilvum_PYR-GCK PWLSDHVIYGTVVVPGATYAAMALAAVGTP--AHAKDVFFYEPIILPEKS
MSMEG_0408|M.smegmatis_MC2_155 PWLADHVIYGTVVVPGATYAAMALAAVGTP--ARLKDVFFYEPIILPEKA
TH_4621|M.thermoresistible__bu PWLADHQIHTVAALPGAAYCEMALAAAREVIDSDGVEVRDVRFEQMLLLD
: : : :
MMAR_0707|M.marinum_M AAQLDAGQAFSDAG------------------------------------
Rv0405|M.tuberculosis_H37Rv AAGLDAGQAFADSG------------------------------------
Mb2074c|M.bovis_AF2122/97 SVAVQVVVNGPDESGVRGVSVYSRGDVGTG--WVLHAEGALRAGSAEPTA
MUL_2266|M.ulcerans_Agy99 SVAVQVVVGSPDDSGARAVSVYSRGDAGSD--WVLHAEGSLGSGSPEPAT
MAV_2450|M.avium_104 SVAIQVVVDGPDDSGARAVSVFSRADAGAG--WLLHAEGVLRAGSAQPAT
MLBr_00135|M.leprae_Br4923 GVQVQVVVAAADESSRRAVSVYSRGDQSHGG-WLLNAEGLLEVDAAEATV
MAB_0939|M.abscessus_ATCC_1997 SREVQLTLHPLEDGSGSKFQVHSRPYGERDVDWSLNAEGTVVTGIGDDAE
Mvan_0269|M.vanbaalenii_PYR-1 SREVQLTLHPSEDG-GQKFQVHSREYGERGTEWSLNAEGTVASGVDENPQ
Mflv_0405|M.gilvum_PYR-GCK SREVQLTVHPSVDG-ESKFQVHSRPYGERGAEWALNAEGVVASGVGDSPA
MSMEG_0408|M.smegmatis_MC2_155 SREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSDPDA
TH_4621|M.thermoresistible__bu EQTEVSAVASAVEPGTLEFAVETAKDGEHERRATAVLGAADDTEPPQAHD
MMAR_0707|M.marinum_M -----------------------------------------LTSLSAVEL
Rv0405|M.tuberculosis_H37Rv -----------------------------------------FNSLSAVEL
Mb2074c|M.bovis_AF2122/97 DLA---------MWPPAGAVPVEVADGYQQLAERGYGYGPAFRGLTAMWR
MUL_2266|M.ulcerans_Agy99 DLS---------TWPPVGAVEVENADGYQQLAERGYGYGPAFRGLNAMWR
MAV_2450|M.avium_104 DLS---------AWPPVGAVPVDLGDGYEQLAERGYRYGPAFRGLTSMWR
MLBr_00135|M.leprae_Br4923 DLS---------LWPPEGAESVDISDAYPQLAERGYAYGPAFQGLVAIWR
MAB_0939|M.abscessus_ATCC_1997 PAPEAAEPAEPVDAAIERMERMRPMELFEIFADLELAWGPTWSGSLKSLW
Mvan_0269|M.vanbaalenii_PYR-1 -----AEPSGPVDEAIERLNRMRPQDLFETFADMELAWGPTWSGSLKSLW
Mflv_0405|M.gilvum_PYR-GCK AAG---DLEDPVDEAIERLNRMRPQELFETFADLELAWGPTWSGSLKSLW
MSMEG_0408|M.smegmatis_MC2_155 AAD---EQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLW
TH_4621|M.thermoresistible__bu IDA----------LLAEHPTRIEGDELRQWFDQRGVQFGPAFTGLTAARI
.
MMAR_0707|M.marinum_M RN-----------------------------RLKTLTGVTLS--------
Rv0405|M.tuberculosis_H37Rv RN-----------------------------RLTAVTAVTLP--------
Mb2074c|M.bovis_AF2122/97 RGDEVF---AEVALPADAGVSVTGFGVHPVLLDAALHAVVLSAESAERG-
MUL_2266|M.ulcerans_Agy99 RGDEVF---AEVALPADAGVSVSGFGIHPVMLDAALHAVILASDGADDFG
MAV_2450|M.avium_104 RGDEIF---AEVNLPTDAGVSTTGFGVHPVMLDAALHAVMLASDGDDLP-
MLBr_00135|M.leprae_Br4923 RGSELF---AEVVAPT--GVVVDGMGMHPALLDAVLHALGLAIENTQAT-
MAB_0939|M.abscessus_ATCC_1997 LGEGEA---IGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAA
Mvan_0269|M.vanbaalenii_PYR-1 LGEGEA---IGDILVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAA
Mflv_0405|M.gilvum_PYR-GCK LGEGEA---IGDILVGAELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAA
MSMEG_0408|M.smegmatis_MC2_155 LGDGEA---VGDILVGAELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAA
TH_4621|M.thermoresistible__bu PEGTVTSVLAEVGLPGQIRSQQAPYGIHPALLDACFQSVAAHPDVQGAGS
.:
MMAR_0707|M.marinum_M ----------------------------ATTAFDYPTPTQLADHLLSHLH
Rv0405|M.tuberculosis_H37Rv ----------------------------ATAIFDHPTPTELAQYLITQID
Mb2074c|M.bovis_AF2122/97 ---------QGSVLVPFSWQGVSLHAAGASAVRARIAPVGPSAVSIELAD
MUL_2266|M.ulcerans_Agy99 VP-------EGSVLVPFAWQGVTLHAAGASAVRARIAPAGPSAVSIELSD
MAV_2450|M.avium_104 ---------AGSMLVPFSWQRVSLHAAGAAAVRARIVPVSPSAVSIELAD
MLBr_00135|M.leprae_Br4923 ----------TEMRLPFCWRGVSLHAGGAGRVRARFTSAGADAIAVDIAD
MAB_0939|M.abscessus_ATCC_1997 EQGVNDLFLPLRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLD
Mvan_0269|M.vanbaalenii_PYR-1 EQGVSDLFLPLRYGQVTLRDKMPRRFYCRATWHTSELDSETQVFDLDFLD
Mflv_0405|M.gilvum_PYR-GCK EQGVNDLYLPLRYGQVSLQEKMPRRFYCRATWHEAPLDSETQVFDLEYLD
MSMEG_0408|M.smegmatis_MC2_155 EQGVNDLFLPLRYGQVTLAEKMPRRFYCRARWHRSALDSETQVFELEFVD
TH_4621|M.thermoresistible__bu G-------LLLPLGVRRLQAFGPTRGARYCYARVTDADGSKAEADLDVLD
: .
MMAR_0707|M.marinum_M HQN--PTGATPELDRVDALTDLFLQTCDAG--------------------
Rv0405|M.tuberculosis_H37Rv GHGSSAAAAANPAERIDALTDLFLQACDAG--------------------
Mb2074c|M.bovis_AF2122/97 GLGLPVLSVASMLARPVTDQQLRAAVSSSG---PDRLFEVTWSPQPSAAV
MUL_2266|M.ulcerans_Agy99 GLGLPVLSVASMLARPVTDQQLRAAVSGAG---PDRLFGVDWTAQPSAEL
MAV_2450|M.avium_104 GLGLPVLSVASMVARPVTDQQLLAAVSNSG---PDRLFELIWSAQPSTAV
MLBr_00135|M.leprae_Br4923 SAGLPVLTVRSLVTRAMTAEQLRTAVTAAGGALEQGPMDLVWSPIPLSSD
MAB_0939|M.abscessus_ATCC_1997 RDGRHLGGIREFTVKRAPREALLRGLGGDATR---LLYTLGWHEVAVPPV
Mvan_0269|M.vanbaalenii_PYR-1 RDGRHLGGIREFTVKRAPREALLRGLGGDATR---LLYTLGWHEVPAPAS
Mflv_0405|M.gilvum_PYR-GCK RDGRHLGGVREFTVKRAPREALLRGLGGDATR---LLYTLGWHEVPVPES
MSMEG_0408|M.smegmatis_MC2_155 LGGRALGGIREFTVKRAPREALLRGLGGDATR---LLYTLGWHEVPPPPS
TH_4621|M.thermoresistible__bu EHGNVLLRVQGLLMGGAAADGDDRDRVLGERLLTIEWQRRDLPEADSAAG
. .
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 EP--------------------------------LPVCAWGTTEDS----
MUL_2266|M.ulcerans_Agy99 QP--------------------------------VPVRIWGTVESEGDDD
MAV_2450|M.avium_104 QP--------------------------------VSLLNWGATELDATDT
MLBr_00135|M.leprae_Br4923 GHG----------------------------GGLPSVVSWADYCAGRGND
MAB_0939|M.abscessus_ATCC_1997 AGEGEESAASIGTWLIAGFDELAAKVPGCIPLNRETDPELLGEVLVAAKE
Mvan_0269|M.vanbaalenii_PYR-1 G-----DAALNGNWLIAGFDELAAGVPGCIPFDRSTDPEPLGQLLAQAHE
Mflv_0405|M.gilvum_PYR-GCK G----DGAAPQGTWLIGGFDELAVSVPGCIPADR-TNPESLRQLLTDAHG
MSMEG_0408|M.smegmatis_MC2_155 A------DDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHA
TH_4621|M.thermoresistible__bu KWLLVSTSATADVSATRLSDALKQAGAESTSMCWPQQADHADNVDRFRAG
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 ------AAVVFESVPLAG------DVVAGVYAATSSVLDVLQSWLT----
MUL_2266|M.ulcerans_Agy99 PG----ASVVFESVPQAG------EVVAGVYAATAAVLEVLRSWLS----
MAV_2450|M.avium_104 DSDSGRFAVLFESAPVAG------DVVTEVYAATRAVLPVLQSWLA----
MLBr_00135|M.leprae_Br4923 TG-----VVVWEFGSASAGAQAPVDSVAAVYSATHAALQVLQFWFG----
MAB_0939|M.abscessus_ATCC_1997 RGVPFSGVVWRAAGPGATES--TTESAARLEGEIAHLLSAVHTVQNSAQN
Mvan_0269|M.vanbaalenii_PYR-1 RGIGFSGVVWRAAAPSADES--STAMAARIETEIADLLSAVHTVQN---G
Mflv_0405|M.gilvum_PYR-GCK RGLPFSGVVWRAARSDGDES--DAEVAARLEAEIAELLGAVHTVQG---G
MSMEG_0408|M.smegmatis_MC2_155 RGAGFSGVVWRCATPGRKESGSASAESARLEAEITNLLSAVHAAQG---P
TH_4621|M.thermoresistible__bu IADGVTGVVVLTGPKNGNPDDAAARRGSDYVRHLVRITRELAEIDG----
MMAR_0707|M.marinum_M -RDDDG-------------------------WQIVALAANGRE-------
Rv0405|M.tuberculosis_H37Rv -RDADG-------------------------WKMVALASNTRE-------
Mb2074c|M.bovis_AF2122/97 -RDGAGVLVVMTRGAVALPGEDVTDLAGAAVWGLVRSAQTEHPGRIVLVD
MUL_2266|M.ulcerans_Agy99 -RDGAGQLIITTRGAVALPDEDVTDLAGSAVWGLVRSAQTEHPGRIVLVD
MAV_2450|M.avium_104 -RDGAGTLVVSTRGAMTLPGEDVTDLAGAAVWGLVRSAQTEHPGRIVLVD
MLBr_00135|M.leprae_Br4923 -QDRAGTLVVLTRGAVGLVGEGISDLAAAAVWGMVRSAQSEHSGKIVLID
MAB_0939|M.abscessus_ATCC_1997 GVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRAKLV
Mvan_0269|M.vanbaalenii_PYR-1 AVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRCRLV
Mflv_0405|M.gilvum_PYR-GCK EVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLV
MSMEG_0408|M.smegmatis_MC2_155 SVKLPGGLWIVTEHGVACESGEPVDPVQAALWGFGRTTINEEPALHCRLV
TH_4621|M.thermoresistible__bu ---DAPRLFVVTRGAQAVLPQDRPNLEQAGLRGLLRVIGAEHPHLRTTQI
: .
MMAR_0707|M.marinum_M -------------------------------------------------R
Rv0405|M.tuberculosis_H37Rv -------------------------------------------------R
Mb2074c|M.bovis_AF2122/97 SDAPLDDSALAAVVTTGEP-----QVLWRRGEVYTARVHGS----RAVGG
MUL_2266|M.ulcerans_Agy99 TDAQLDEHAVAAVLAAGEP-----QVLWRNGEVYTARVHGS----RAVAG
MAV_2450|M.avium_104 TDAPLDADAVAAVLAVGEP-----QTLLRNGTVYTARVLGS----RAVGA
MLBr_00135|M.leprae_Br4923 TDSAVD---VAVLADLGES-----QLLVRCNTVHAARLS------PAPQL
MAB_0939|M.abscessus_ATCC_1997 DGDGSPEAVQALARLLVTP-VDEPEIAVRQGKLLASRLLPW----SRTGH
Mvan_0269|M.vanbaalenii_PYR-1 DVDGSPEAVLALAGLLAAP-VDEPELAVRQGKLLASRLLPW----ARSGH
Mflv_0405|M.gilvum_PYR-GCK DCDGSPQAVQALAALLSTP-VDEPELAVRQGKLLASRLLPW----SRSGH
MSMEG_0408|M.smegmatis_MC2_155 DCDGSSEAVDLLAALLAAPGIQEPEIAVRQGKLLASRLLPW----ARSGH
TH_4621|M.thermoresistible__bu DIADDADLDRVAVQLLGGG--AEDETAWRDGQWYTARLSLSPLRPEERKQ
MMAR_0707|M.marinum_M MTTPVPKREWKEVVLLAGGRSDVAVVCLPTLTVLSSPHAYLDVARAMAGR
Rv0405|M.tuberculosis_H37Rv MSSPVRNNVSKNVALLADGISDVVVICIPTLTVLSDQREYRDIANAMTGR
Mb2074c|M.bovis_AF2122/97 LLVPPSDRPWRLAMSTAGTFENLRLELIPDADAPLGPGQVRVAVSAIAAN
MUL_2266|M.ulcerans_Agy99 LLVPPGDGPWRLGMSTAGTFENLRLEPIPDADAALQPGHVRVALSAMAAN
MAV_2450|M.avium_104 LLVPPEDGPWRLGMSSYGTIENLRLEPIPDADAPLGPGQVRVATSALAAN
MLBr_00135|M.leprae_Br4923 LALPVGESMWRLAADGGGTLEDLVIQPCPEVQAPLQAGHMRVAVAAVGVN
MAB_0939|M.abscessus_ATCC_1997 LTVP-RGSDYVLAPTERGAIDNLRITEKEVPAPD--EGYVQVRVEAAGLN
Mvan_0269|M.vanbaalenii_PYR-1 LTVP-RSADYVLAPTERGAIDNLRLTETDVAPPA--EGYVQVRVEAAGLN
Mflv_0405|M.gilvum_PYR-GCK LTVP-RGGDYVLAPTERGAIDNLRLTDSEVPPPA--EGYVQVRVEAAGLN
MSMEG_0408|M.smegmatis_MC2_155 LTLP-RGGDFVLAPTERGAIDNLRLTETDVPEPD--EGYVQVRVEAAGLN
TH_4621|M.thermoresistible__bu AVVDCERDGMRLEIRTPGDLETMELAAFDRVPPG--PGQIEVAVTASSIN
. . : : * .
MMAR_0707|M.marinum_M HSVHALSLPGFDPDD---ALP--QDREVVLEGAAQAILHAVG--------
Rv0405|M.tuberculosis_H37Rv HSVYSLTLPGFDSSD---ALP--QNADMIVETVSNAIIDVVG--------
Mb2074c|M.bovis_AF2122/97 FRDVMIALGLYPDPD---AVMGVEACGVVIETSLNKGSFAVGDRVMGLFP
MUL_2266|M.ulcerans_Agy99 FRDVMIALGLYPDPD---AAMGVEGAGVVVETASPDGRFAVGDRVVGLFP
MAV_2450|M.avium_104 FRDVMIALGLYPDPD---AVMGIEASGVVIETASQDGRVAVGDRVMGLFP
MLBr_00135|M.leprae_Br4923 FRDVVAALGMYPGQA---PPLGAEGAGVVIEIGPEVTGVAVGDAVMG-FL
MAB_0939|M.abscessus_ATCC_1997 FRDVLNVLGLYPGDP---GPIGGDFAGIVTQLGEGVTGVEVGQRVYGSMQ
Mvan_0269|M.vanbaalenii_PYR-1 FRDVLNVLGLYPGDP---GPIGGDFAGTVTQLGSGVTGLEVGQRVYGFMQ
Mflv_0405|M.gilvum_PYR-GCK FRDVLNVLGLYPGDP---GPIGGDFAGTVTQLGEGVTGLDVGQRVYGSMQ
MSMEG_0408|M.smegmatis_MC2_155 FRDVLNVLGLYPGDP---GPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQ
TH_4621|M.thermoresistible__bu FADVLIAFGRYPTFDGRRPQLGTDFAGVVTAVGPDVTSHRVGDRVGGLSP
. : : : : :*
MMAR_0707|M.marinum_M -------------------------------------------------D
Rv0405|M.tuberculosis_H37Rv -------------------------------------------------G
Mb2074c|M.bovis_AF2122/97 -EGTGTVASTDQRLLVKVPAGWSHTAAATTSVVFATAHYALVDLADVQPG
MUL_2266|M.ulcerans_Agy99 -EGTGTIAITDHRLLVKIPAGWSDTAAATTSVVFATAFYALRDLASVQPG
MAV_2450|M.avium_104 -DGTGTVATTDQRLLVKVPAGWSHTAAATASVVFATAYYALVDLADARPG
MLBr_00135|M.leprae_Br4923 -GGAGPLAVVHQQLITQMPQGWSLAEAAAVPVVFLTALFGLADLAGIRAG
MAB_0939|M.abscessus_ATCC_1997 -GAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVR-LSFDWAQLKPG
Mvan_0269|M.vanbaalenii_PYR-1 -GAFASRFNVPAQLLAPIPDGIGAVDAATIPAAALTAR-LAFDWAQLKPG
Mflv_0405|M.gilvum_PYR-GCK -GAFASRFNVPGQFLAPIPDGVSAVEAATIPAAALTVR-LSFDWAQVKSG
MSMEG_0408|M.smegmatis_MC2_155 -GAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVR-LAFDWAQLKPG
TH_4621|M.thermoresistible__bu NGCWSTFVTCDADLAVPLPDGLTEGQAAAVSTAHATAWYGLHDLARLGAG
.
MMAR_0707|M.marinum_M HPHLVLAGYSSGGVLAHALGSYLAERHQRTP-------------------
Rv0405|M.tuberculosis_H37Rv SCRFVLSGYSSGGVLAYALCSHLSVKHQRNP-------------------
Mb2074c|M.bovis_AF2122/97 QRVLIHAGTGGVGMAAVQLARHLGLEVFATASKGKWDTLRAMGFDDDHIS
MUL_2266|M.ulcerans_Agy99 QRILVHAATGGVGMAAVQLARHWGLEVFATASKGKWDTLRAMGFDEDHIG
MAV_2450|M.avium_104 QRVLVHAAAGGVGMAAVQLARHLGLEVFATASRGKWDTLRDMGFDDDHLG
MLBr_00135|M.leprae_Br4923 ESVLIHAGTGGVGMAAVQFARHWGVEIFVTASRGKWDTLRDMGFDDDHIG
MAB_0939|M.abscessus_ATCC_1997 DKVLIHAASGGVGLAAIQMAQQFGAEVFATASTFKRATLRKLG--VKYVY
Mvan_0269|M.vanbaalenii_PYR-1 DRVLIHAASGGVGLAAIQMAQQHGAVVFATASTYKRATLRKLG--VDHVY
Mflv_0405|M.gilvum_PYR-GCK DKVLIHAASGGVGLAAVQMAQQCGAEVYATASTFKRATLRKLG--VKHVY
MSMEG_0408|M.smegmatis_MC2_155 DKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTLRRLG--VKYVY
TH_4621|M.thermoresistible__bu EKVLIHSATGGVGLAAIAIARSVGAQIYATAGSPARRDLLRDMG-IEHVY
:: :. .. *: * : . ..
MMAR_0707|M.marinum_M -----------------LGVALIDTYLPSQ-IVNADN-------------
Rv0405|M.tuberculosis_H37Rv -----------------LGVALIDTYLPSQ-IANPSM-------------
Mb2074c|M.bovis_AF2122/97 DSRSLEFEDKFRAATGGRGFDVVLDSLAGE-FVDASLRLVAPGGVFLEMG
MUL_2266|M.ulcerans_Agy99 DSRSLEFEDKFRAATGGRGMDVVLDSLAGE-FVDASLRLVAPGGVFLEMG
MAV_2450|M.avium_104 DSRGLDFEDKFRAVTGGAGMDIVLDSLSGD-SVDASLRLVAPGGIFLEMG
MLBr_00135|M.leprae_Br4923 DSRTLEFEEKFLAVTDGRGVDVVLDSLAGD-FVDASLRLLVRGGRFLEMG
MAB_0939|M.abscessus_ATCC_1997 DSRTTDFADQILADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRFAEIA
Mvan_0269|M.vanbaalenii_PYR-1 DSRTTEFADQILADTDGEGVDVVLNSLTNEGFIEATVRATAQNGRFAEIA
Mflv_0405|M.gilvum_PYR-GCK DSRTTDFAEQILADTDGAGVDVVLNSLTSEGFIEATLRATAQHGRFAEIA
MSMEG_0408|M.smegmatis_MC2_155 DSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKATAQGGRFAEIA
TH_4621|M.thermoresistible__bu DSRSTAFADEIRRDTDGYGVDVVLNSLPGA-AQRAGLELLSFGGRFIEIG
*. :: *.. .
MMAR_0707|M.marinum_M --------------------PDQVGVNETG--------------------
Rv0405|M.tuberculosis_H37Rv --------------------NEGFSPNDTG--------------------
Mb2074c|M.bovis_AF2122/97 KTDIRDPGVI--AQQYPGVRYRAFDLFEAGPDRIAQILAELATLFGDGVL
MUL_2266|M.ulcerans_Agy99 KTDIREAAVV--AQQHTGVRYRAFDLFEAGPDHIAQILAELAALFSEDVL
MAV_2450|M.avium_104 KTDIRDPEVV--AAEHPGVRYRAFDLFEAGPDRIARLLDELAAMFGEDVL
MLBr_00135|M.leprae_Br4923 KTDIRDAQEI--AANYPGVQYRAFDLSEAGPVRMQEMLCEVRELFDTQVL
MAB_0939|M.abscessus_ATCC_1997 KRDIWTTEQM--AQSRPDIAYEIVALDTVMFQEPDRIRVLLTEVSEGLAK
Mvan_0269|M.vanbaalenii_PYR-1 KRDIWTPEQM--AAARPDIAYEIVALDTVTLLEPERIRGLLGEVSDGLGK
Mflv_0405|M.gilvum_PYR-GCK KRDIWTVEQM--AAARPDLAYEIVALDTVMFTEPDRIRDLLTEVSAGLRD
MSMEG_0408|M.smegmatis_MC2_155 KRDIWSHEQM--AEARPDIAYEIVALDTVMFTEPDRIRDLLTEVSDGMAR
TH_4621|M.thermoresistible__bu KRDIYGDTRLGLFPFRRNLAFHGVDLGLMADSHPHKIRELLETVYRLTAD
.
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 R---------PLPVTTFDVRRAPAALRYLSQARHTGKVVMLMP----GSW
MUL_2266|M.ulcerans_Agy99 R---------PLPVTTFDVRRAPAALRYLSQARHVGKVVLTMP----DAW
MAV_2450|M.avium_104 R---------PLPVTRFDVRRAPAALRYLSQARHVGKVVMTMP----DAW
MLBr_00135|M.leprae_Br4923 H---------RLPVTSWDVRCAPAAFRFMSQARHIGKVVLTMPSALADGL
MAB_0939|M.abscessus_ATCC_1997 G------EWTPLPAEIYPLTEARTAFRRMQQARHIGKIVCQMPNP--LAP
Mvan_0269|M.vanbaalenii_PYR-1 ADGSSRAEWVPLPAEIYPLTEARAAFRRMQQARHVGKIVLQMPKP--LQP
Mflv_0405|M.gilvum_PYR-GCK G------AWTPLPAEVYPLTEARAAFRRMQQARHIGKIVVQIPNP--LQP
MSMEG_0408|M.smegmatis_MC2_155 G------EWTPLPAEIYPITEARSAFRRMQQARHIGKIVLQVPKP--LQP
TH_4621|M.thermoresistible__bu G------VLPMPQSTHYPLAEAATAIRVMSAAEHVGKLVLDVPHTG----
MMAR_0707|M.marinum_M ---------------ALFSRRVTSMARELDQLNATR--------------
Rv0405|M.tuberculosis_H37Rv ---------------KGLSREVIRVARMLNRLTATR--------------
Mb2074c|M.bovis_AF2122/97 AAGTVLITGGTGMAGSAVARHVVARHGVRNLVLVSRRGPDAPGAAELVAE
MUL_2266|M.ulcerans_Agy99 AAGTVLITGGTGMAGSALARHVVAHHGVRQLVLVSRRGPDAPGAAELAEE
MAV_2450|M.avium_104 TAGTVLITGATGMAGSAVARHVVTRHGARNLVLVSRRGLDAPDAAELVAE
MLBr_00135|M.leprae_Br4923 AEGTVLITGASGAIGGVLARHMVSAYGVRHLVLASRRGDRAEGAVELAAE
MAB_0939|M.abscessus_ATCC_1997 RPDRTYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRAPDTDAQRVIGEI
Mvan_0269|M.vanbaalenii_PYR-1 RADRSYLITGGLGAIGLHTAAYLAQLGAGDLVLTSRRAPDADARRAIEEI
Mflv_0405|M.gilvum_PYR-GCK QPDRSYLITGGLGAIGLHTAGYLAQLGAGDIVLTSRRAPDAAAQQAIADI
MSMEG_0408|M.smegmatis_MC2_155 QQDRSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEI
TH_4621|M.thermoresistible__bu RADVVVPPEQASPFRSDGAYIVTGGMGGLGLYLAGEMAAAGAGCIVLNGR
: . .
MMAR_0707|M.marinum_M -----------LTAAASYAALFGTWEPVVSAVP----LLNMIAMDETAAC
Rv0405|M.tuberculosis_H37Rv -----------LTAAATYAAIFQAWEPGRSMAP----VLNIVAKDRIATV
Mb2074c|M.bovis_AF2122/97 LAAAGAQVQVVACDAADRAALAKVIADIPVQHP-LSGVIHTAGALDDAVV
MUL_2266|M.ulcerans_Agy99 LSAFGAQVQVVACDAADRAALAKLIADIPMQHP-LSAVIHTAGALDDAVV
MAV_2450|M.avium_104 LTAAGAHAEVVACDAADREALAKVIADIPMQHP-LTGVIHAAGVLDDAVV
MLBr_00135|M.leprae_Br4923 LVGAGAKIQVVACDVADNDAVRGLFAQLSREFPPVRGVIHAAGVLDDGAI
MAB_0939|M.abscessus_ATCC_1997 TERSKTRIHVFTADVGAESEVAGLLERIRAELPPLAGVAHLAGVLDDALL
Mvan_0269|M.vanbaalenii_PYR-1 TERYKCRVHTFCADVGDESQVAELLARIRAELPPLAGVAHLAGVLDDALL
Mflv_0405|M.gilvum_PYR-GCK ADRTKARLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALL
MSMEG_0408|M.smegmatis_MC2_155 TERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHLAGVLDDALL
TH_4621|M.thermoresistible__bu SAPSGEALRTIEQLRAAGTEVIVECGXXXRGQP-VEVAVPTELRHADEHP
. : *
MMAR_0707|M.marinum_M ERVRAERINRWRVATAEASYSVVEVP-----------GDHFDMITTSSDA
Rv0405|M.tuberculosis_H37Rv ENLREERINRWRTAAAEAAYSVAEVP-----------GDHFGMMSTSSEA
Mb2074c|M.bovis_AF2122/97 MSLTPDRVDVVLRSKVDAAWHLHELTRDLDVSAFVMFSSMAGLVGSSGQA
MUL_2266|M.ulcerans_Agy99 TSLTPERIETVLRAKVDAAWNLHELTRDMDLSAFVMFSSMAGLVGSSGQG
MAV_2450|M.avium_104 TSLTPQRIDTVLRAKVDAAWNLHELTRDLDVGAFVMFSSIAGLAGASGQG
MLBr_00135|M.leprae_Br4923 TSLTPDRVDTVLRAKVDAAWNLHEATRDLDLLMFVLCSSIAATVGSPGQG
MAB_0939|M.abscessus_ATCC_1997 GQQSVERFRTTLAPKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGSPGQS
Mvan_0269|M.vanbaalenii_PYR-1 SQQSLERFRTTLAPKAFGACHLDRLTAGDDLDFFIMSSSVSSLFGSPGQA
Mflv_0405|M.gilvum_PYR-GCK SQQSVERFRTALAPKAFGAVHLDRLTRVDDLDFFLVSSSVSSLFGSPGQS
MSMEG_0408|M.smegmatis_MC2_155 SAQNPERFRTTLAPKAYGASHLDRLTRDDDLDFFIVSSSVSSLFGSPGQA
TH_4621|M.thermoresistible__bu DRRGAQLCDEFARGEQGAQRNQHRTDAGEGQRDAHPPGAVGHDQPDPGAL
: . . . ..
MMAR_0707|M.marinum_M TTTALHGWISGLIRAG----------------------------------
Rv0405|M.tuberculosis_H37Rv IATEIHDWISGLVRGPHR--------------------------------
Mb2074c|M.bovis_AF2122/97 NYAAANSFLDALAAHRRAHGLPAISLGWGLWDQASAMTSGLATVDFKRFA
MUL_2266|M.ulcerans_Agy99 NYAAANSFLDGLAVHRQAHGLPAISLGWGLWDQASNMTGGLAAVDFKRFA
MAV_2450|M.avium_104 NYAAGNSFLDGLAAHRRAHGLPAISLGWGLWDQASAMTGGLGAADLARFG
MLBr_00135|M.leprae_Br4923 NYSAANAFLDGLAAYRQAAGLAGTSLAWGLWEQPGGMNAHLSSRDLARIS
MAB_0939|M.abscessus_ATCC_1997 NYATANALLDGLIAQRRAQGLPATGINFGPWGQGGMASSEAATANIS---
Mvan_0269|M.vanbaalenii_PYR-1 NYATANALLDGLTAHRRARGLPATGVNFGPWAQGGMASSEAATANIG---
Mflv_0405|M.gilvum_PYR-GCK NYATANAFLDGLVAQRRAQGLPATGVNFGPWARGGMASSEAAAANIS---
MSMEG_0408|M.smegmatis_MC2_155 NYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEAATANIT---
TH_4621|M.thermoresistible__bu SDTGLDERGGQFPGVGVQIPVADPGVGIDHRGAVRVDSGVPAQQGVDG--
: . . :
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 RDGIVAMSSADALQLFDTAMIVDEPFMLPAHIDFAALKVKFDGGTLPPMF
MUL_2266|M.ulcerans_Agy99 RDGIVAMSSDEALGLLDTAMVLGEPFMLPAHIDFAALRVKFDGGTLPPMF
MAV_2450|M.avium_104 RDGIVAMSSQEALELMDTALIVDEPFLLPAHIDLAALRVKFDGGTLPPMF
MLBr_00135|M.leprae_Br4923 RSGLAPMNPAQALELFDAALVIDHPFMVTALLDRAALDAQAQAGALPPLF
MAB_0939|M.abscessus_ATCC_1997 ---------AQGLIPLDPSAALAALAEVVANGTGQATILKANWQRAAKVL
Mvan_0269|M.vanbaalenii_PYR-1 ---------AQGLVPLEPSAALGALAEVLANGTGQAAVLKANWQRAAKVL
Mflv_0405|M.gilvum_PYR-GCK ---------AQGLIPLEPSAALTAMAEVVANGTAQATVLKANWQRAAKVL
MSMEG_0408|M.smegmatis_MC2_155 ---------AQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVL
TH_4621|M.thermoresistible__bu -------------------------EVVRHRTLSSVRSGRSSRWTAPGSR
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 VDLINAPTRRQVDDSLAAAKSKSALAHRLHGLPEDEQHAVLLDLVRSHIA
MUL_2266|M.ulcerans_Agy99 VDLINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQHAILLNLVRSHIA
MAV_2450|M.avium_104 VDLINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQQAVLLDLVRSNIA
MLBr_00135|M.leprae_Br4923 SRLVRRSRRRQIEDPGDATQSKLALVQRLQGLAANRQLELLVGVVCLQAA
MAB_0939|M.abscessus_ATCC_1997 GSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGFVTEFLQREVQ
Mvan_0269|M.vanbaalenii_PYR-1 GSSRPPILDLVLPRPEGEVAGDSELLRQLQEIPVAQRAGFVTEFLQREVQ
Mflv_0405|M.gilvum_PYR-GCK GSSRPPILDLVLPSAVGEITGDSELLKQLQEIPVPQRAGFVTEFLQKEVQ
MSMEG_0408|M.smegmatis_MC2_155 GSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQ
TH_4621|M.thermoresistible__bu CGSGRRYGGESCRRTTGPAAGAAARRGRTRRRRRPRRPPPPPDRVRHRAG
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 TVLGSASPEAIDPDRAFQDLGFDSLTAVEMRNRLKSATG--LSLSPTLIF
MUL_2266|M.ulcerans_Agy99 TVLGNSSPDAIDPDRAFQELGFDSLTAVEMRNRLKSATG--LALSPTLIF
MAV_2450|M.avium_104 TVLGSSSPEAIHPDRAFQELGFDSLTAVEMRNRLKAATG--LALSPTLIF
MLBr_00135|M.leprae_Br4923 AVLGRPSPEDIDPNTKFQDLGFDSLTAVELRNRLKSATG--LTLPPTVIF
MAB_0939|M.abscessus_ATCC_1997 NFLRLAQPPAATSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVF
Mvan_0269|M.vanbaalenii_PYR-1 NFLRLAQPPAATSR--FLDLGTDSLMAIELRNRLHSQFGGAFTINATAVF
Mflv_0405|M.gilvum_PYR-GCK NFLRLAQPPAATSR--FLDLGTDSLMAIELRNRLHSQFGGAFTINATAVF
MSMEG_0408|M.smegmatis_MC2_155 NFLRLASPPAASSR--FLDLGTDSLMAIELRNRLHSQFGGKFTINATAVF
TH_4621|M.thermoresistible__bu PAHGPVRR------------------------------------------
MMAR_0707|M.marinum_M --------------------------------------------------
Rv0405|M.tuberculosis_H37Rv --------------------------------------------------
Mb2074c|M.bovis_AF2122/97 DYPNSAALAGYMRRELLGSSPQ-DTSAVAAGEAELQRIVASIPVKRLRQA
MUL_2266|M.ulcerans_Agy99 DYPNSAALAGYMHRELVGASPQSDTTAEAPGEAELQRVVASIPVKRLRQA
MAV_2450|M.avium_104 DYPNSAALAGYMYRELVGTSEQ-PTAAAAPGEAEIQRVVGSIPVKRLRQA
MLBr_00135|M.leprae_Br4923 DHPTPTAVAEYVAQQMLKSRPA----------------------------
MAB_0939|M.abscessus_ATCC_1997 DYPTIGGLAEYLVGQLPDADAE----------------------------
Mvan_0269|M.vanbaalenii_PYR-1 DYPTIGGLAEYLVGQLPDSDAA----------------------------
Mflv_0405|M.gilvum_PYR-GCK DYPTIGGLAEYLVAQLPD--------------------------------
MSMEG_0408|M.smegmatis_MC2_155 DYPTIGGLAEYLVGQLPD--------------------------------
TH_4621|M.thermoresistible__bu --------------------------------------------------
MMAR_0707|M.marinum_M -------------------------------------------------
Rv0405|M.tuberculosis_H37Rv -------------------------------------------------
Mb2074c|M.bovis_AF2122/97 GVLDLLLALANETETSGQDPALAPTAEQEIADMDLDDLVNAAFRNDDE-
MUL_2266|M.ulcerans_Agy99 GVLELLLALANETGGNGQAAVTAETSEEDLADMDLDALVNAAFMNDDE-
MAV_2450|M.avium_104 GVLELLLALANESTGTAQSATPAVTTEKDIADMDLDDLVNAALLDDDDE
MLBr_00135|M.leprae_Br4923 -----------ESGDETSQAVEPKVEEVSVHA-----------------
MAB_0939|M.abscessus_ATCC_1997 ---------SAEAPPAVESAEAESGAGPAAASDAVSELKE---------
Mvan_0269|M.vanbaalenii_PYR-1 ---------AGETPATETSPIDHNHPDREADSPG---------------
Mflv_0405|M.gilvum_PYR-GCK ----------AETPQAAPQSESEPGPDVTE-------------------
MSMEG_0408|M.smegmatis_MC2_155 ----------AEAPETA--------------------------------
TH_4621|M.thermoresistible__bu -------------------------------------------------