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M. ulcerans Agy99 MUL_1655 (pks9)

annotation: polyketide synthase Pks9
coordinates: 1817861 - 1820953
length: 1030

VMSRATSLRRQHGDGDQEFASAVAIIGVACRIPGAANPGEFWELVSEGHEVAKPIDHVGDFDAEFFNVSP
REATAMDPRQRLALELAWELFEDARIVAESVRGEPIAVYLGAMNDDYALLTLDQAPDKLDHYSFAGASRG
MIANRVSSGFALHGPSMTVDCGQSSSLVAVHLAPGYLRGAGDATMAIAGGIHLNLASETGRLETEFGAVS
ASGRTYAFDARADGYVRSEGGGLVLLKPLRAALEDGNSIRAVILGEAVGSAGHTAGGLAAPSAAAEADVM
RRAMASAGVDPNQIDYIEAHGTGTRIGDTTEAQALSEVFATRETPVWLGSVKSNIGHTGAAAGAAGLIKT
VLSLENGAIPASLNFVGDSAGTDMESHGLHVSTTLTPWPRGAGPRRAGVSSFGMGGTNAHVIVQQAPIPQ
EAVADPDGTEATVPWLVSARSRAALAGQAQRLAAWVAELPSIDVADVGWSLLSTRSVFEHRAVLVGGDRG
GFMAGLAALASGEPGVNLVAGRAGSGGKTVLVFPGQGAQWLGMGRDLYGRFPAFAKAFDTVADALDEHLR
LPLREVIWGADASLLEGTEFAQPALFALEVALAALLQACGVVADLVMGHSVGEISAAHVAGVLSLTDAAR
LVSARGRLMAQLPPGGVMVAVAASAAQVAPMLQEGVSIAAVNGPDSVVISGPEAATAVVADRLTGQGCRA
HRLAVSHAFHSALMEPMMVQFGATISGIVAHEPRIALVSNMTGQLAAAGYGTASYWVEHVRKPVRFADGV
ALAESLGAATFLETGPSAGLGTSVALLAKGRPEVESLLTAMGQLYVDGADLDWRAAFAGLRARTVTLPTY
SFARQRFWLGEGAGRKADSSDESGLRPRLDSVDSKERFRQLVDLVCLHAAIATGHSNSHQIDAERAFQGL
GFESMTGVELRNRLRAVTGLALSRTIIFDYTTPMALARHLDEQLSGGNHEESDDDKIWSVLRTIPVRELR
RSGMLDKLLLLAGQDERPAPDAAVSDDVIDSLSPEALVAMALDSEDDDPD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1655pks9-100% (1030)polyketide synthase Pks9
M. ulcerans Agy99MUL_2005pks15/10.046.72% (899) polyketide synthase Pks15/1
M. ulcerans Agy99MUL_2266pks120.045.22% (889) polyketide synthase, Pks12

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1692pks90.062.97% (1018) polyketide synthase pks9
M. gilvum PYR-GCKMflv_0405-1e-15638.80% (897) beta-ketoacyl synthase
M. tuberculosis H37RvRv1664pks90.063.06% (1018) polyketide synthase pks9
M. leprae Br4923MLBr_00135-0.045.19% (894) putative polyketide synthase
M. abscessus ATCC 19977MAB_0939-1e-15639.13% (892) polyketide synthase
M. marinum MMMAR_2473pks90.098.54% (1029) polyketide synthase Pks9
M. avium 104MAV_3107-0.061.64% (1027) polyketide synthase
M. smegmatis MC2 155MSMEG_0408-1e-15338.29% (888) type I modular polyketide synthase
M. thermoresistible (build 8)TH_4458-1e-14034.35% (1080) PUTATIVE putative Fatty acyl-AMP ligase FadD28_1 and polyketide
M. vanbaalenii PYR-1Mvan_0269-1e-15739.09% (898) beta-ketoacyl synthase

CLUSTAL 2.0.9 multiple sequence alignment


MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      MDSAENPIESTPRFAIIGYAARFPGAADAEEFWDVLREGRDAISEVPADR
Mvan_0269|M.vanbaalenii_PYR-1       MGSAEHPNGPAPRFAIVGYAARFPGAPDADAFWDVLREGRDAISDVPRDR
Mflv_0405|M.gilvum_PYR-GCK          MGSAAHQGESAHRFAIVGYAGRFPGARDAESFWELLADGRDAISEVPEDR
MSMEG_0408|M.smegmatis_MC2_155      MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDR
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      WDAEEFFDPEPGAPGKVVTRRAGFVEDVTGFDAPFFGMSTREVRLMDPQH
Mvan_0269|M.vanbaalenii_PYR-1       WDAEEFFDPEPGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRMMDPQH
Mflv_0405|M.gilvum_PYR-GCK          WDVEAFFDPDPSTPGKVVTRRAGFVDDVSGFDAPFFGMSTREVRLMDPQH
MSMEG_0408|M.smegmatis_MC2_155      WDIEEFFDPDPSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQH
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      RLLLETAWRAVEHSGIAPTDLAETNSGVFVGLATHDYLGMASDELTFPEI
Mvan_0269|M.vanbaalenii_PYR-1       RLLLETAWRAVEHSGTAPTALAGSNTGVFVGLATHDYLGMASDELTYPEI
Mflv_0405|M.gilvum_PYR-GCK          RLLLETAWRAIEHSGTAPSELANTNTGVFVGLATHDYLGMASDELSYPEI
MSMEG_0408|M.smegmatis_MC2_155      RILMETAWRAVEHSGIAPTSLANSNTGVFVGLATHDYLGMASDELTYPEI
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      EAYMAIGTSNAAAAGRISYRLGLQGPSVAVDTACSSSLVAIHQACQALQL
Mvan_0269|M.vanbaalenii_PYR-1       EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
Mflv_0405|M.gilvum_PYR-GCK          EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
MSMEG_0408|M.smegmatis_MC2_155      EAYMAIGTSNAAAAGRISYRLGLQGPAVAVDTACSSSLVAIHQACQALRL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      GECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDAAADGYVRGEG
Mvan_0269|M.vanbaalenii_PYR-1       GECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
Mflv_0405|M.gilvum_PYR-GCK          GECDLALAGGANVILTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
MSMEG_0408|M.smegmatis_MC2_155      NECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDAAADGYVRGEG
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      SGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
Mvan_0269|M.vanbaalenii_PYR-1       CGVIVIKRLEDAVRDGDRIRAVIRGSSINQDGASGGLTVPNGVAQQRVIA
Mflv_0405|M.gilvum_PYR-GCK          CGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIG
MSMEG_0408|M.smegmatis_MC2_155      CGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      DALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAGAAYGIGRETNDPLLI
Mvan_0269|M.vanbaalenii_PYR-1       DALKRSDLEPKDVGYLEAHGTGTSLGDPIEAQAAGAVLGAGREPSRPLLI
Mflv_0405|M.gilvum_PYR-GCK          DALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAGAALGPGREPQRPLLI
MSMEG_0408|M.smegmatis_MC2_155      DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLI
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      GSAKTNIGHLEAAAGIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLP
Mvan_0269|M.vanbaalenii_PYR-1       GSAKTNIGHLEAAAGIAGVIKVILSLEHRTLPKHLNFENPSPHIPWDRLA
Mflv_0405|M.gilvum_PYR-GCK          GSAKTNIGHLEAAAGIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDRLP
MSMEG_0408|M.smegmatis_MC2_155      GSAKTNIGHLEAAAGIAGVIKVVMALENETLPKHLNFETPSPHIPWERLP
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      VEVVREARPWGRN---GRPRIAGVSSFGFAGTNAHVILEEAPVVSRDAVE
Mvan_0269|M.vanbaalenii_PYR-1       VEVVKETIPWERD---GGPRIAGVSSFGFAGTNAHVILEEAP--EQAAAP
Mflv_0405|M.gilvum_PYR-GCK          VEVVKESIPWRRGQRGGRPRIAGVSSFGFAGTNAHVILEEAP---LAAEP
MSMEG_0408|M.smegmatis_MC2_155      IEVVRETVPWQRN---GKPRIAGVSSFGFAGTNAHVILEEAPAVGTPATT
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      PPAPAGGRKFSILPLSARTPAALAQLADKYRAWLNAHPEAALADLCFTAG
Mvan_0269|M.vanbaalenii_PYR-1       GPVQQPDRRFSLLPLSARTPAALTQLAGQYRDWWTAHPEATLADVCFTAG
Mflv_0405|M.gilvum_PYR-GCK          AQESVDDGRFTLLPLSARTPAALMAVADRYRDWLVANPDATLADLCFTAG
MSMEG_0408|M.smegmatis_MC2_155      EPVE-DPRRYSVLPLSARTPEALVRLAGEYRDWLRAHPQARLADVSHTAG
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      VGRAHLEHRAALVVNTREAAVELLSAVADDRPAPGLGRGESHDTPKTAWL
Mvan_0269|M.vanbaalenii_PYR-1       AGRAHLEHRAALVVNSAESAVELLGALADDRPAPGLVRGESHDTPKTAWL
Mflv_0405|M.gilvum_PYR-GCK          TARSHLEHRAALVVNTREAALDLLGALADDRPAPGLVRGESHDTPKTAWL
MSMEG_0408|M.smegmatis_MC2_155      TARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEAPKTAWL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      FTGQGSQYPGMARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVD-
Mvan_0269|M.vanbaalenii_PYR-1       FTGQGSQYPGMARELYDTEPVFAETLNRCAEAVADVLEKPLLDVIFDAE-
Mflv_0405|M.gilvum_PYR-GCK          FTGQGSQYPGMSRELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDG
MSMEG_0408|M.smegmatis_MC2_155      FTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDAD-
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      --GPEAEETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYS
Mvan_0269|M.vanbaalenii_PYR-1       --ADDAEKTLQNTCYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYS
Mflv_0405|M.gilvum_PYR-GCK          VLDTDSNETLRHTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYA
MSMEG_0408|M.smegmatis_MC2_155      ELDGDTESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYS
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      AACVAEVFSLEDGARLIAERGRLFSSLPAGGRMAAVFTDAERAERLTDEF
Mvan_0269|M.vanbaalenii_PYR-1       AACVAGVFSLTDGARLMAERGRLFGSLPEGGRMVAVFTTAERAEAMTDEF
Mflv_0405|M.gilvum_PYR-GCK          AACVAGVLSLRDGARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEY
MSMEG_0408|M.smegmatis_MC2_155      AACVAGVFDVEDGARLIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEY
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      PSLSVAAYNGANTVLSGPAQDLEKAIAALVADGVRCDFLETSHAFHSALL
Mvan_0269|M.vanbaalenii_PYR-1       PSLSVAAYNGTNTVLSGPAGDLEKAVATLSADGVRCDWLDTSHAFHSALL
Mflv_0405|M.gilvum_PYR-GCK          PALSVAAYNGANTVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALL
MSMEG_0408|M.smegmatis_MC2_155      PSLSVAAYNGANTVLSGPAKDLESAVATLVADGVRCDWLDTSHAFHSALL
TH_4458|M.thermoresistible__bu      ------------------LLSLLRQRSERYGDKIAFDYCTGEQEHSRLTY
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      DPILDEFEAYANQFNYKTPQRILIDNRTGTALGRSVKLDGAYWRRHARQP
Mvan_0269|M.vanbaalenii_PYR-1       DPILDDFESYANQFDFAAPQRILIDNRTGTALGRSVQLDGTYWRRHARQP
Mflv_0405|M.gilvum_PYR-GCK          DPILDDFESYARGITFTAPQRILIDNRTGAALGRSVTLDAAYWRRHARQP
MSMEG_0408|M.smegmatis_MC2_155      DPILDDFESFAQKLEYREPQRILIDNRTGSALGRSTRLDGAYWRRHARQP
TH_4458|M.thermoresistible__bu      QELDIRARAIAAHLQDQGVAGERVLVLCPSGLDFITAMFGCFYVGAVAVP
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      VEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAWPDPATAPRAIASLRR
Mvan_0269|M.vanbaalenii_PYR-1       VEFAKSVRTLAEMNCKLLVEIGPRPVLTAAALGAWPDPATAPRVIASLRR
Mflv_0405|M.gilvum_PYR-GCK          VEFAKSVHTLADMNCKLLVEIGPRPVLTAAALSAWPDPATSPRVIASLRR
MSMEG_0408|M.smegmatis_MC2_155      VEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVLASLRP
TH_4458|M.thermoresistible__bu      VHPPVHNRLLSRVASIVADVRATSVLTTAATRADLKEILDGLHDGDPLRW
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      NTADHRQITEAAADAYVLGHLPDFGAFQHAPARKLDLPTYPFERRQYWFS
Mvan_0269|M.vanbaalenii_PYR-1       TAADHRQITEAVADAYVLGHLPEFGAFRDAGARKLDLPTYPFEHRQYWFR
Mflv_0405|M.gilvum_PYR-GCK          TTADQRQITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFS
MSMEG_0408|M.smegmatis_MC2_155      TTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFS
TH_4458|M.thermoresistible__bu      LAVDTIEADDETSWTPTTVDTDSVAFVQYTSG------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      DKRDGDNRDAGNRQQNNGGPRTEAVRLLEDGKIEELANLLGGVDGDQQTL
Mvan_0269|M.vanbaalenii_PYR-1       DNQDPD----GSEALQPRTPSTEAVRLLEDGRIEELATLLDGAAGDQQTL
Mflv_0405|M.gilvum_PYR-GCK          DSREPV------AAAPQRGARTETVRLLEDGRIEELAALLGGTVDDPFTF
MSMEG_0408|M.smegmatis_MC2_155      DNRAIDRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTL
TH_4458|M.thermoresistible__bu      ----------------------------------STSTPKGVVLTHHNLL
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      NVLTKLAAQHNLQRTTQTIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVA
Mvan_0269|M.vanbaalenii_PYR-1       DVLSRLAAQHNQQRSSQSITNDRYEIRWEQSAAALSGAETDEVSSWILVG
Mflv_0405|M.gilvum_PYR-GCK          DVLNRLAAQHNQQRSTESIADDRYQIRWETAAEPPVGADAADGITWLLVG
MSMEG_0408|M.smegmatis_MC2_155      RVLNKLAARHNQQRSTHVDPDARYEIRWDAIAS--AAASTGAAADWILVG
TH_4458|M.thermoresistible__bu      ANLESISRDAGQGDEARVVSWLPLHHDMGLIGGIFGVVHFGGTAYLMPPS
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      DAAGAAQPLLDVLTARGQQHRVLALPVSDADEAELVEALRSAADEDSALR
Mvan_0269|M.vanbaalenii_PYR-1       DDTEATRPLVDVLSARGQRYRIFGLPVSDADEEQLGEALRLAAAEDSTLR
Mflv_0405|M.gilvum_PYR-GCK          DDTDATRPLVDVLAARGHRYRILGLPKSGAEEHELADTLRDAAADATDLR
MSMEG_0408|M.smegmatis_MC2_155      DDTAAVLEFADALTAGGHRHQIVALPGSDADEAQLVDTLRAASAG--ELY
TH_4458|M.thermoresistible__bu      SFIQRPMSWLEAISWHGANISVGPNFGYQLCVERSTPEERATLDLSTWVR
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      IVHVAALAGQ----GSSSAQSLLRIQHQVLGGTRRLFRAAAAAELRAPIW
Mvan_0269|M.vanbaalenii_PYR-1       IVHVGGLDSDPDPGTAPSMRSLLRMQHRILGGTRRLFRAAAAAELRTPIW
Mflv_0405|M.gilvum_PYR-GCK          IVHVAALDAA---ESDTSMKSLLRMQHRVLGGTRRLFGAAVAAQLRSPMW
MSMEG_0408|M.smegmatis_MC2_155      VVHIAAGDGA-----AAPMRDLLRVQHRTLGGLRRLFRAANDAELRSPIW
TH_4458|M.thermoresistible__bu      AYCGAEPVRAATMRRFTEAFAPAGFRADAFHPVYGLAEATLFVSGRPENV
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      IVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDAGTDE
Mvan_0269|M.vanbaalenii_PYR-1       VVTRRAQHVTATDTVAPDQSCLWGFGRAAALELPQLWGGLADLADGTADE
Mflv_0405|M.gilvum_PYR-GCK          LVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGGTSDE
MSMEG_0408|M.smegmatis_MC2_155      LVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSG-ADTE
TH_4458|M.thermoresistible__bu      LPTVRSLDNAALREHRVVPAAADDANAAAVVGCGPAAYGEEIVIVDPATR
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      WAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVRSD
Mvan_0269|M.vanbaalenii_PYR-1       WSRLLNRITAPHGPAVREDQIALRDHAVYVPRLVRRAGRPAGKPLQLRDD
Mflv_0405|M.gilvum_PYR-GCK          WSRLLNRIAATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLRAD
MSMEG_0408|M.smegmatis_MC2_155      WPRLIARITSPRD---GEDQIALRGDAVYAPRLVRRTGEPSDTPLPVRED
TH_4458|M.thermoresistible__bu      REFPPDVVGEIWVAGENVAQGYLGKPSESAETFAAHLADSGRGPFLRTGD
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      ATYLVTGGLGSIGLEIAGYLAGRGAKHLVLTSRREPGEAARQRIDALAAQ
Mvan_0269|M.vanbaalenii_PYR-1       ATYLVTGGLGSIGLEIAGYLAAHGARHLVLTSRRAPGDATQQRIDALGAQ
Mflv_0405|M.gilvum_PYR-GCK          ATYLVTGGLGSLGLEIAGYLAANGAGHLVLTSRRTPDEAAASRIEALRER
MSMEG_0408|M.smegmatis_MC2_155      RTYLVTGGLGAIGLEVAGYLASHGAGHVVLTSRREPGDDARRRLDGLREQ
TH_4458|M.thermoresistible__bu      YGFLLDG------------------------ELFVTGRLKDLIIIRGRNY
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      G-CEVRAVTADVADGHDVARLLAGIQAELPPLAGIVHAAGEIGTTPLSDL
Mvan_0269|M.vanbaalenii_PYR-1       HSCQIRVVAADVADAHDVARLLAAVAAELPPLAGIVHAAGEIGTTPLVSL
Mflv_0405|M.gilvum_PYR-GCK          HGCEVRVVTADVADAHAVARLLATVQAEMPPLAGIVHAAGEIGTTPLADL
MSMEG_0408|M.smegmatis_MC2_155      YACDVRVITADVADAHDVARLMTTVAAELPPLAGIVHAAGEIGTTPLSGL
TH_4458|M.thermoresistible__bu      HPNDIEATVQEVHPALMSGRGAAFAVSPDPSGTEQLVIVQEVDRGRLGEV
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      EDAEVDRVFAGKVWGAWHLSEAAAGLK--LDFFINTSSIAAVWGGYGQTA
Mvan_0269|M.vanbaalenii_PYR-1       EDSEVDRVFAGKVWGAWHLSEAAADLQ--LDFFLGTSSIASVWGGYGQTA
Mflv_0405|M.gilvum_PYR-GCK          DDAEVDRVFAGKVWGAWHLSEATSDLQ--LDFFISTSSIASVWGGFGQAA
MSMEG_0408|M.smegmatis_MC2_155      DDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSSIASVWGGFGQTA
TH_4458|M.thermoresistible__bu      DTDELIAAIRTAVTSQHDIGVHTVVLVDPLRIPTTSSGKIRRRTCRQRFL
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      YSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAESRARLEQRGIKT
Mvan_0269|M.vanbaalenii_PYR-1       YGAANAFLDGLAWRLREQGISGVSINFGPWSAGMADAESRARLDQRGVRT
Mflv_0405|M.gilvum_PYR-GCK          YGAANAFLDGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLEQRGIKT
MSMEG_0408|M.smegmatis_MC2_155      YGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQRGVRT
TH_4458|M.thermoresistible__bu      DGELDAFAEWRLATPRPAQPVPAADEQADEQAGAGPGAGPGADEIRAWFV
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      LSPTDALAGLADVVAASGS-NAVQGVIARIDWARFLPLYQQAGKRGFLAE
Mvan_0269|M.vanbaalenii_PYR-1       LSPADALAGLADVVTAAEAPGPAQGIVARIDWERFLPLYQQAGRRAFLAE
Mflv_0405|M.gilvum_PYR-GCK          LSPADALAGLSDAVISAAP----HPVVARVDWSRFLPLYQQAGRRGFLAE
MSMEG_0408|M.smegmatis_MC2_155      LSPAEALAGMADVVAGPVQ-----GVVAKIDWSRFLPLYQQAGRRAFLSE
TH_4458|M.thermoresistible__bu      AQLAGELG------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          --------------------------------------------------
MAB_0939|M.abscessus_ATCC_1997      LDREVPSHLAGV--AGAQSGSTQLVERLANAPVQQRKKLLTDYLRDAVAE
Mvan_0269|M.vanbaalenii_PYR-1       LEREVPDTAP----AATPSGRTELVERLTNAPVQQRKKLLTDYLRTAVAE
Mflv_0405|M.gilvum_PYR-GCK          LERELPAAPAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAE
MSMEG_0408|M.smegmatis_MC2_155      LESELPAAATGAAAPATVPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAE
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          ---------------------------------------MTASVEGADQK
MAB_0939|M.abscessus_ATCC_1997      VTRVDVSEIREDAGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPR
Mvan_0269|M.vanbaalenii_PYR-1       ITRVDATEIREDAGFFDLGMDSLMAVELRRRIEQGVGREIPATLAMDHPR
Mflv_0405|M.gilvum_PYR-GCK          VTRVDAAEIREDAGFFDLGMDSLMAVELRRRIETGVGKEIPVTLVMDHPR
MSMEG_0408|M.smegmatis_MC2_155      VTRVDADEIRDEAGFFDLGMDSLMAVELRRRIEQGVGKDIPVTLVMDHPR
TH_4458|M.thermoresistible__bu      ---LSPDDIDTGQPFAYYGLDSVRAIQLMTALEAWSGIKVAPTLAYDHPT
                                                                                      

MUL_1655|M.ulcerans_Agy99           ----------MMSRATSLR------------RQHGDGDQEFASAVAIIGV
MMAR_2473|M.marinum_M               -----------MSRATSLR------------RQHGDGDQEFASAVAIIGV
Mb1692|M.bovis_AF2122/97            ---------------------------------------MQPTGIAIIGL
Rv1664|M.tuberculosis_H37Rv         ---------------------------------------MQPTGIAIIGL
MAV_3107|M.avium_104                ---------------------------------------MPPTDVAIIGM
MLBr_00135|M.leprae_Br4923          SEKLISYLKKVVVELDETR------------ARLREYEQRATEPVAVVGI
MAB_0939|M.abscessus_ATCC_1997      ISDVADYLLGDVLGLAEQA--K------PAAQLASAVTGRTDEPIAIVAV
Mvan_0269|M.vanbaalenii_PYR-1       LSDVADYLLGEVLGLAEQAPAK------AGSQPASAAANRTDEPIAIVAV
Mflv_0405|M.gilvum_PYR-GCK          LSDAADYLLGDVLGLTEAA---------TAPKAATVVSTAADEPIAIVAV
MSMEG_0408|M.smegmatis_MC2_155      LSDAADYLLVEVLGLGEQT----------NVRQASTVTARTDDPIAVVAV
TH_4458|M.thermoresistible__bu      IDLAAEHLAGLTHTATSTAADAGVSTGAGRRPEHGPAPDRADEPIAIIGI
                                                                                :*::.:

MUL_1655|M.ulcerans_Agy99           ACRIPG-AANPGEFWELVSEGHEVA-------------------------
MMAR_2473|M.marinum_M               ACRFPG-AANPGEFWELVSEGHEVA-------------------------
Mb1692|M.bovis_AF2122/97            ACRFPT-VVSPGDLWDLLRDGREAT-------------------------
Rv1664|M.tuberculosis_H37Rv         ACRFPT-VVSPGDLWDLLRDGREAA-------------------------
MAV_3107|M.avium_104                ACRFPG-APDPGSFWRLLRDGREVT-------------------------
MLBr_00135|M.leprae_Br4923          GCRFPGGVDSPDRLWDVVSECRDVVSEFPTDRGWDVDGLFDPDPDAEGKT
MAB_0939|M.abscessus_ATCC_1997      SCRFPG-APDPEAFWDVLSGGVDAIREVPEDR-FDIDEFYDPDPEVAGKT
Mvan_0269|M.vanbaalenii_PYR-1       SCRFPG-APDPEAFWEVLAGGVDAIREVPEDR-FDIDEFYDPDPDAAGKT
Mflv_0405|M.gilvum_PYR-GCK          SCRFPG-APNPEAFWDLLSGGVDAIREVPEDR-FDIDEFYDPDPDAAGKT
MSMEG_0408|M.smegmatis_MC2_155      SCRFPG-APDPESFWELLAGGVDAIREVPEDR-WDIDEFYDPDPDTPGKT
TH_4458|M.thermoresistible__bu      GCRFPG-ADGPAAYWRLLREGRDAITATPPER----------WDTDSVGD
                                    .**:*  . .*   * ::    :.                          

MUL_1655|M.ulcerans_Agy99           -----KPIDHVGDFDAEFFNVSPREATAMDPRQRLALELAWELFEDARIV
MMAR_2473|M.marinum_M               -----KPIDHVGDFDAEFFNVSPREAAAMDPRQRLALELAWELFEDARIV
Mb1692|M.bovis_AF2122/97            -----GSIDNVADFDADFFNLSPREASAMDPRQRLALELTWELLEDAFVV
Rv1664|M.tuberculosis_H37Rv         -----GSIDNVADFDADFFNLSPREASAMDPRQRLALELTWELLEDAFVV
MAV_3107|M.avium_104                -----RFAGEAAEFDADFFNLSPREAAAMDPRQRLALELAWELLEDAFIV
MLBr_00135|M.leprae_Br4923          YTRWGAFLDDAAGFDAGFFGIAPSEVLAMDPQQRLMLEVSWEALEYAGID
MAB_0939|M.abscessus_ATCC_1997      YTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYS
Mvan_0269|M.vanbaalenii_PYR-1       YTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGLA
Mflv_0405|M.gilvum_PYR-GCK          YTRYGGFLDHIDEFDPEFFGLSPREAVWIEPQQRLMLETVWEGLERAGYA
MSMEG_0408|M.smegmatis_MC2_155      YTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYA
TH_4458|M.thermoresistible__bu      GTRWGGFLERIDGFDAGFFGISPREAVRIDPQQRLLLEVAWEALEDAGLV
                                                 **. **.::* *.  ::*:*** **  ** :* *   

MUL_1655|M.ulcerans_Agy99           AESVRGEPIAVYLGAMNDDYALLTLDQAPDKLDHYSFAGASRGMIANRVS
MMAR_2473|M.marinum_M               AESVRGEPIAVYLGAMNDDYALLTLDQAPDKLDHYSFAGASRGMIANRVS
Mb1692|M.bovis_AF2122/97            PETLRGQPIAVYLGAMNDDYAVLTL--AADRVDHHAFAGTSRAIIANRVS
Rv1664|M.tuberculosis_H37Rv         PETLRGQPIAVYLGAMNDDYAVLTL--AADRVDHHAFAGTSRAIIANRVS
MAV_3107|M.avium_104                AETLRGEAVSVYLGAMTDDYAALTLRDVPDNVDHHTFTGVSRGMIANRIS
MLBr_00135|M.leprae_Br4923          PLSLRGSATGVFTGIFAPSYGSRDT----GGLQGYGLTGTAVSVASGRVS
MAB_0939|M.abscessus_ATCC_1997      PAALRGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVA
Mvan_0269|M.vanbaalenii_PYR-1       PADLRGSRTGIFVGVAANEYAHLLSSESIEKIEPHFITGNALNAISGRVA
Mflv_0405|M.gilvum_PYR-GCK          PSALRGSRTGVFVGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVA
MSMEG_0408|M.smegmatis_MC2_155      PSDLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVA
TH_4458|M.thermoresistible__bu      PDRLAGSRTGVFTGVSTYDYLHLQLS-HPELIDAYSGTGTASSIAANRLS
                                    .  : *.  .:: *    .*           :: :  :* :    :.*::

MUL_1655|M.ulcerans_Agy99           SGFALHGPSMTVDCGQSSSLVAVHLAPGYLRGAGDATMAIAGGIHLNLAS
MMAR_2473|M.marinum_M               YGFALHGPSMTVDCGQSSSLVAVHLAREYLRGAGDATMAIAGGIHLNLAS
Mb1692|M.bovis_AF2122/97            FAFGLRGPSVTIDSGQSSSLVAVHLACESVR-TGEAPLAIAGGVHLNLAR
Rv1664|M.tuberculosis_H37Rv         FAFGLRGPSVTIDSGQSSSLVAVHLACESVR-TGEAPLAIAGGVHLNLAR
MAV_3107|M.avium_104                YLLGLRGASMTVDSGQSSSLVAVHLGCESVR-SGQAPLAIAGGVHLNLAD
MLBr_00135|M.leprae_Br4923          YVLGLEGPAVSVDTACSSSLVAIHWAMSSLR-SGECDLALAGGVTVMGLP
MAB_0939|M.abscessus_ATCC_1997      FALGFEGPAVAVDTACSSALVAVHQAVQALH-SGDCDLALAGGVNVLLSP
Mvan_0269|M.vanbaalenii_PYR-1       FALGLEGPAVAVDTACSSALVAVHQACQALH-SGDCDLALAGGVNVLLSP
Mflv_0405|M.gilvum_PYR-GCK          FALGLEGPAVAVDTACSSSLVAVHQATQALR-SGDCDMALAGGVNVLLSP
MSMEG_0408|M.smegmatis_MC2_155      FALGFEGPAVAVDTACSSALVAVHQACQALQ-SGDCDLALAGGVNVLLSP
TH_4458|M.thermoresistible__bu      YVFDFRGPSLTLDSACSSSLVAVHQACRSLR-DGECDLALAGGVNIMLSA
                                      : :.*.::::* . **:***:* .   ::  *:. :*:***: :    

MUL_1655|M.ulcerans_Agy99           ETGRLETEFGAVSASGRTYAFDARADGYVRSEGGGLVLLKPLRAALEDGN
MMAR_2473|M.marinum_M               ETGRLETEFGAVSASGRTYAFDARADGYVRSEGGGLVLLKPLRAALEDGN
Mb1692|M.bovis_AF2122/97            ETAMLEQEFGAVSPSGHTYAFDERADGYVPGDGGGLVLLKPVQAALDDGD
Rv1664|M.tuberculosis_H37Rv         ETAMLEQEFGAVSPSGHTYAFDERADGYVPGDGGGLVLLKPVQAALDDGD
MAV_3107|M.avium_104                EIALLEREFGAVSVSGHTYAFDRRADGYVRGEGGGLVLLKPLAAARRDGD
MLBr_00135|M.leprae_Br4923          SIFVGFSRQRGLAADGRCKAFARAADGTGWGEGAGVVVLERLSDAQRLGH
MAB_0939|M.abscessus_ATCC_1997      VTVIAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAERDGD
Mvan_0269|M.vanbaalenii_PYR-1       VTSVAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLGDAVRDGD
Mflv_0405|M.gilvum_PYR-GCK          VTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGILVLKRLSDAVRDGD
MSMEG_0408|M.smegmatis_MC2_155      VTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGD
TH_4458|M.thermoresistible__bu      GIGLNFTRAGVMATDGRCKTFDARADGWVRGEGAGIVVLKPLREALADED
                                           .   ::  *:  :*   ***   .:* *:::*: :  *    .

MUL_1655|M.ulcerans_Agy99           SIRAVILGEAVGSAGHTAGGLAAPSAAAEADVMRRAMASAGVDPNQIDYI
MMAR_2473|M.marinum_M               RIRAVILGAAVGSAGHTAGGLAAPSAAAEADVMRRAMASAGVDPNQIDYI
Mb1692|M.bovis_AF2122/97            RIHAIIRGSAVGNAGHSATGLTVPSVAGQVDVIRRAMSGAGVDCHQVHYV
Rv1664|M.tuberculosis_H37Rv         RIHAIIRGSAVGNAGHSATGLTVPSVAGQVDVIRRAMSGAGVDCHQVHYV
MAV_3107|M.avium_104                RIHAVIRATAVGNAGHGAPAQTLPSAAAEADVIGRALAEAGLGGADIDYV
MLBr_00135|M.leprae_Br4923          TVLAVVRGSAVNQDGASN-GLTAPNGLAQQRVIQAALTNAGLSSADVDVV
MAB_0939|M.abscessus_ATCC_1997      RVLAVIPGSAVNQDGASS-GLTVPNGGAQQRLIGSVLARAGLVGGDVDYL
Mvan_0269|M.vanbaalenii_PYR-1       RVCAVIPSSAVNQDGASS-GLTVPNGGAQQRLIGMALARAGLSGGDVDYL
Mflv_0405|M.gilvum_PYR-GCK          RVCAVIAGSAVNQDGASS-GLTVPNGGAQQRLIGTVLARAGITGGEVDYL
MSMEG_0408|M.smegmatis_MC2_155      RVCAVIPASSVNQDGASS-GLTVPNGGAQQRLIEATLARAGLSGADVDYL
TH_4458|M.thermoresistible__bu      PIYAVIRGSAVNQDGRTN-GLMAPSRTAQEVVLTDAYRRAGVSPGVVQYV
                                     : *:: . :*.. *    .   *.  .:  ::  .   **:    :. :

MUL_1655|M.ulcerans_Agy99           EAHGTGTRIGDTTEAQALSEVFATR---ETPVWLGSVKSNIGHTGAAAGA
MMAR_2473|M.marinum_M               EAHGTGTRIGDTTEAQALSEVFATR---ETPVWLGSVKSNIGHTGAAAGA
Mb1692|M.bovis_AF2122/97            EAHGTGTKIGDPIEARALGEIFAARQ--RRPVSVGSVKTNIGHTGGAAGI
Rv1664|M.tuberculosis_H37Rv         EAHGTGTKIGDPIEARALGEIFAARQ--RRPVSVGSVKTNIGHTGGAAGI
MAV_3107|M.avium_104                EAHGTGTRVGDAVETQALGRIFAERS--HHPVSVGSVKTNIGHAASAAGI
MLBr_00135|M.leprae_Br4923          EAHGTATTLGDPIEAQALLATYGQGRPADQPLWVGSIKSNMGHTQAAAGV
MAB_0939|M.abscessus_ATCC_1997      EAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMGSVKSNIGHTESASGA
Mvan_0269|M.vanbaalenii_PYR-1       EAHGTGTPLGDPIEVQAAAAAYGASRDADRPLLMGSVKTNIGHLESASGA
Mflv_0405|M.gilvum_PYR-GCK          EAHGTGTPLGDPIEVQAAAAAYAGARDADRPLLMGSVKTNIGHTESASGA
MSMEG_0408|M.smegmatis_MC2_155      EAHGTGTPLGDPIEVQAAAAAYGAGRDADRPLLMGSVKTNIGHTESASGA
TH_4458|M.thermoresistible__bu      EAQGIGTPVGDAIEVGALGTVLAEDRPPDSPCLIGSVKTNIGHLEAAAGI
                                    **:* .* :**. *. *     .       *  :**:*:*:**  .*:* 

MUL_1655|M.ulcerans_Agy99           AGLIKTVLSLENGAIPASLNFVGDSAGTDMESHGLHVSTTLTPWPRGAGP
MMAR_2473|M.marinum_M               AGLIKTVLSLENGAIPASLNYVGDSAGTDMESHGLHVSTTLTPWPRGAGP
Mb1692|M.bovis_AF2122/97            AGLLKAVLAIENAVIPPSLNYVG--APIDLDSLGLRVDTALTPWPVADEP
Rv1664|M.tuberculosis_H37Rv         AGLLKAVLAIENAVIPPSLNYVG--AAIDLDSLGLRVDTALTPWPVADEP
MAV_3107|M.avium_104                AGLLKAVLAIEHAAIPPNLHFERPDPDIDLNRLGLRVNTALAPWPDRGGP
MLBr_00135|M.leprae_Br4923          AGVIKMVQAMRHHVMPATLHVDEPSPRVDWTTGAVSVLTEARDWSVEGRP
MAB_0939|M.abscessus_ATCC_1997      AGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQANGRP
Mvan_0269|M.vanbaalenii_PYR-1       AGLIKVVLSLQHNLLPQSLHFENPSPHIPWDSLPVRVVDKAIPWQADGRP
Mflv_0405|M.gilvum_PYR-GCK          AGLIKVVLSLQHETLPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQPNGRP
MSMEG_0408|M.smegmatis_MC2_155      AGLIKVVLSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRV
TH_4458|M.thermoresistible__bu      AGLIKVALALRHRMIPPTLNFTEPNPTIEFDKLPVRVAQTLTPWPDDSGR
                                    **::* . ::.:  :* .*:     .        : *      *      

MUL_1655|M.ulcerans_Agy99           RRAGVSSFGMGGTNAHVIVQQAPIP--------------QEAVADPDGTE
MMAR_2473|M.marinum_M               RRAGVSSFGMGGTNAHVIVQQAPIP--------------QEAVADPDGTE
Mb1692|M.bovis_AF2122/97            RRAGVSSFGMGGTNAHVILEQGPTQSPEI---------VESVAAAGSNAP
Rv1664|M.tuberculosis_H37Rv         RRAGVSSFGMGGTNAHVILEQGPTQSPEI---------VESVAAAGSNAP
MAV_3107|M.avium_104                RRAGVSSFGMGGTNAHVIVEQDAAQ--------------QNPTPASAPAD
MLBr_00135|M.leprae_Br4923          RRAGVSSFGISGTNAHVILEEAPTP---V---------EASYSTADQQRL
MAB_0939|M.abscessus_ATCC_1997      RRAGVSSFGFTGTNAHVLIEEAPQPQATP----------DEDDASTPQSA
Mvan_0269|M.vanbaalenii_PYR-1       RRAGVSSFGFTGTNAHVLIEEAPLPQAAD----------PVEEPDT-RAL
Mflv_0405|M.gilvum_PYR-GCK          RRAGVSSFGFTGTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPA
MSMEG_0408|M.smegmatis_MC2_155      RRAGVSSFGFTGTNAHVLVEEAPPQLHTADAAP----VEPAATAEAGTDD
TH_4458|M.thermoresistible__bu      AVAGVSAFGFGGTNAHVVLAEAPQVR-------------AAATADDHADG
                                      ****:**: ******:: : .                    .      

MUL_1655|M.ulcerans_Agy99           ATVPWLVSARSRAALAGQAQRLAAWVAELPSIDVADVGWSLLSTRSVFEH
MMAR_2473|M.marinum_M               ATVPWLVSARSRAALAGQAQRLAAWVAELPSIDVADVGWSLLSTRSVFEH
Mb1692|M.bovis_AF2122/97            VAVPWVLAARSPQALTNQAGRLLAHLTADDGLTALDVGWSLVSTRSVFDH
Rv1664|M.tuberculosis_H37Rv         VAVPWVLAARSPQALTNQAGRLLAHLTADDGLTALDVGWSLVSTRSVFDH
MAV_3107|M.avium_104                VALPWVLSARSERALALQAQRLSAHLAERPQASPLDVGWSLVSARAVFEH
MLBr_00135|M.leprae_Br4923          SVVPWVVSGRSTAALMAQASRLAFYVQADPEVDPVDVGCALA-ARSVFEH
MAB_0939|M.abscessus_ATCC_1997      PVSVLPLSARSPEALAAVAQRYESWLAAHPDVDLEDVCLTAGRGRSHFEH
Mvan_0269|M.vanbaalenii_PYR-1       PVGVLALSARSPEALTALAQRYEAWLSAHPDADLADVCRTAGTGRSHFEH
Mflv_0405|M.gilvum_PYR-GCK          PVEVLPLSARSPEALVALAQRYETWLTAHPEADLADVCRTAGTGRSHFEH
MSMEG_0408|M.smegmatis_MC2_155      SPQVLALSARSPEALVELARRYDDWLSATPGLDIADVCHTAGVGRSHFEY
TH_4458|M.thermoresistible__bu      FVEILPLSARSQAALDALAERYESALTG--GVPPADLCHTAGARRAHHDH
                                          ::.**  **   * *    :         *:  :    *: .::

MUL_1655|M.ulcerans_Agy99           RAVLVGGDRGGFMAGLAALASGEPGVNLVAGRAGSGGKT--VLVFPGQGA
MMAR_2473|M.marinum_M               RAVLVGGDRGGFMAGLAALASGEPGVNLVAGRAGSGGKT--VLVFPGQGA
Mb1692|M.bovis_AF2122/97            RAVVVGADRGRLMAGLAGLAAGEPGAGVVVGRARSVGKT--VFVFPGQGS
Rv1664|M.tuberculosis_H37Rv         RAVVVGADRGRLMAGLAGLAAGEPGAGVVVGRARSVGKT--VFVFPGQGS
MAV_3107|M.avium_104                RAVLVGCERGVLATGLAGVASGRPDAATVVGRARATGKT--VLVFPGQGS
MLBr_00135|M.leprae_Br4923          RAVVVGESREQLIAGLAGLAVGESGAGVAIGQAAPLGKT--VVVFPGQGA
MAB_0939|M.abscessus_ATCC_1997      RAALVVDSIQTAREGLLELAQNRLRPGVVRGEHTNHPTT--AWLFTGQGS
Mvan_0269|M.vanbaalenii_PYR-1       RAALVVDSVAAAREGLAELAQNRLRPGVVRGEHTHHPTT--AWLFTGQGS
Mflv_0405|M.gilvum_PYR-GCK          RAALVVDSVESARIALTDLAQNRLRPGVVRGEHLNHPTT--AWMFTGQGS
MSMEG_0408|M.smegmatis_MC2_155      RAALVVDSVERAREGLAALAEGRTPAGVVRGEHVHRPTT--AWLFTGQGS
TH_4458|M.thermoresistible__bu      RLAVVGASRAELIGALAAYRRGEPHPGVFTGRSQSGHRSGVVFVFSDEGS
                                    * .:*  .      .*     ..       *.      :  . :*..:*:

MUL_1655|M.ulcerans_Agy99           QWLGMGRDLYGRFPAFAKAFDTVADALDEHLRLPLREVIWGAD-------
MMAR_2473|M.marinum_M               QWLGMGRDLYGRFPAFAKAFDTVADALDEHLRLPLREVIWGAD-------
Mb1692|M.bovis_AF2122/97            QWLGMGRQLYGRYSVFARAFDEVVAVLDGQLRLSVRQVMWGAD-------
Rv1664|M.tuberculosis_H37Rv         QWLGMGRQLYGRYSVFARAFDEVVAVLDGQLRLSVRQVMWGAD-------
MAV_3107|M.avium_104                QTLGMGRQLYERFVVFARALDEAVAVVDEHSRLSVREVMWGAD-------
MLBr_00135|M.leprae_Br4923          QRIGMGRELCSQLPVFAEEFDAVTGELDRHMRLPLRDVVWGAD-------
MAB_0939|M.abscessus_ATCC_1997      QYPGMARELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGGKA
Mvan_0269|M.vanbaalenii_PYR-1       QFPGMARELFETEPVFADAVTRCADAVKDILPRPLLEVLFAADRESG---
Mflv_0405|M.gilvum_PYR-GCK          QYPGMARELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGGREAGVPP
MSMEG_0408|M.smegmatis_MC2_155      QYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETA---
TH_4458|M.thermoresistible__bu      QWRGMAQRLYAEDQVFRTALAECDRALRRHMEISPLSELLADPS------
                                    *  **.: *     .*   .      :      .  . : .         

MUL_1655|M.ulcerans_Agy99           ASLLEGTEFAQPALFALEVALAALLQACGVVADLVMGHSVGEISAAHVAG
MMAR_2473|M.marinum_M               ASLLEGTEFAQPALFALEVALAALLQACGVVADLVMGHSVGEISAAHVAG
Mb1692|M.bovis_AF2122/97            AGLLESTEFAQPALFVVQVALAALLQDWGVLPDLVMGHSVGEIAAAYVAG
Rv1664|M.tuberculosis_H37Rv         AGLLESTEFAQPALFVVQVALAALLQDWGVLPDLVMGHSVGEIAAAYVAG
MAV_3107|M.avium_104                PELLQSTEFAQPALFVFEVALAALWESLGVTPDVVMGHSVGEIAAACVAG
MLBr_00135|M.leprae_Br4923          AGLLDSTEFAQPALFAVEVALFAVLQHWGLQPDFVMGHSIGELAAAYVAG
MAB_0939|M.abscessus_ATCC_1997      GEALRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAG
Mvan_0269|M.vanbaalenii_PYR-1       -EALRHTSFAQPAIFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAG
Mflv_0405|M.gilvum_PYR-GCK          TETLRHTSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAACVAG
MSMEG_0408|M.smegmatis_MC2_155      -DLLQHTSFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAG
TH_4458|M.thermoresistible__bu      HSRMDEVTIASPALFAVQVALAALWQSWGVEPAAVIGHRMGEVAAAHVAG
                                       :  . :*.**:*..::.*  : :  .: .  *:** :*: :** ***

MUL_1655|M.ulcerans_Agy99           VLSLTDAARLVSARGRLMAQLPPGGVMVAVAASAAQVAPMLQEG--VSIA
MMAR_2473|M.marinum_M               VLSLTDAARLVSARGRLMAQLPPGGVMVAVAASAAQVAPMLEEG--VSIA
Mb1692|M.bovis_AF2122/97            ALSLVDAARVVAARGRLMQALPAGGVMVAVAASEDEVAPLLTEG--VCIA
Rv1664|M.tuberculosis_H37Rv         ALSLVDAARVVAARGRLMQALPAGGVMVAVAASEDEVAPLLTEG--VCIA
MAV_3107|M.avium_104                VLSLRDAARLVAARGALMAALPPGGVMVAVTATEAQVAPLVGGG--VSIA
MLBr_00135|M.leprae_Br4923          VLAPADAAMLVVARGRLMQSMPAGGTMWAVAASEDEVVSLLGEG--VGIA
MAB_0939|M.abscessus_ATCC_1997      VFSIEDGARLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPRVSVG
Mvan_0269|M.vanbaalenii_PYR-1       VFSLEDGARLMAERGRMFGSLPEGGRMVAVFTDAKLVEEIAGDFPRVSVG
Mflv_0405|M.gilvum_PYR-GCK          VFSLEDGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAADFPRVSVG
MSMEG_0408|M.smegmatis_MC2_155      VFSLDDGARLMAERGRMFGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVG
TH_4458|M.thermoresistible__bu      VLGLDDAAALLCGRTRLSRLASTG--------------------------
                                    .:.  *.* ::  *  :    . *                          

MUL_1655|M.ulcerans_Agy99           AVNGPDSVVISGPEAATAVVADRLTGQGCRAHRLAVSHAFHSALMEPMMV
MMAR_2473|M.marinum_M               AVNGPDSVVISGPEAATAVVADRLTGQGCRAHRLAVSHAFHSALMEPMMA
Mb1692|M.bovis_AF2122/97            AVNAPESVVISGEQAAVGVVVDRLVGLGRRVRRLAVSHAFHSVLMDPMVE
Rv1664|M.tuberculosis_H37Rv         AVNAPESVVISGEQAAVGVVVDRLVGLGRRVRRLAVSHAFHSVLMDPMVE
MAV_3107|M.avium_104                AVNGPDAVVLSGEQEAVSAVAERLAGSGARVHRLAVSHAFHSALMEPMLD
MLBr_00135|M.leprae_Br4923          AINAPESVVISGPQAAVSAIADKFAAQGRRVHQLAVSHAFHSPLMEPMLE
MAB_0939|M.abscessus_ATCC_1997      AYNGPN-TVLSGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDPILD
Mvan_0269|M.vanbaalenii_PYR-1       AYNGPN-TVLSGPGEDLEQIVDRFGDDGVRCTWLQTSHAFHSELLDPVLD
Mflv_0405|M.gilvum_PYR-GCK          AYNGPN-TVLSGPGEDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLD
MSMEG_0408|M.smegmatis_MC2_155      AYNGPN-TVLSGPGEDLEEIVERFEDEGIRCTWLATSHAFHSELLDPVLD
TH_4458|M.thermoresistible__bu      ----------------------------------------------AVRE
                                                                                  .:  

MUL_1655|M.ulcerans_Agy99           QFGATISGIVAHEPRIALVSNMTG-QLAAAGYGTASYWVEHVRKPVRFAD
MMAR_2473|M.marinum_M               QFGATISGIVAHEPRIALVSTMTG-QLAAAGYGTASYWVEHVRKPVRFAD
Mb1692|M.bovis_AF2122/97            EFSKVLADVCVRAPRIGLVSNVTG-QLAGAGYGSPAYWVEHVRKPVRFFD
Rv1664|M.tuberculosis_H37Rv         EFSKVLADVCVRAPRIGLVSNVTG-QLAGAGYGSPAYWVEHVRKPVRFFD
MAV_3107|M.avium_104                GFAAAAAGIEPRPPRIPLVSNLTG-QLAGPGYGTPQYWVEHVRRPVRFVD
MLBr_00135|M.leprae_Br4923          EFVRVAAQVEVRKPQIGLVSNVTG-ELAGPDFGSPQYWGEHVSRAVRFVD
MAB_0939|M.abscessus_ATCC_1997      EFESYAAQVQFAAPTLPLVCNRTGAVLTAQTPIDGQYWRRHSRQPVQFAE
Mvan_0269|M.vanbaalenii_PYR-1       EFESYAAQFQFATPTLPLVCNRTGTVLTAQTPLDAQYWRRHSRQPVQFAE
Mflv_0405|M.gilvum_PYR-GCK          EFESYAAQLQFAAPTLPLVCNRTGAVLTGQTSLDAQYWRRHSRQPVQFAE
MSMEG_0408|M.smegmatis_MC2_155      EFEAYAAQFQFAAPTLPLVCNRTGAVLTGQTPLDAQYWRRHSRQPVQFAE
TH_4458|M.thermoresistible__bu      GLDGLLANLRPDDPRIPLYSTVTGDAVTGRGFG-AAHWMENLHSPVRFSA
                                     :    : .    * : * .. **  ::.       :* .:   .*:*  

MUL_1655|M.ulcerans_Agy99           GVALAESLGAATFLETGPSAGLGTSV--------------ALLAKGRPEV
MMAR_2473|M.marinum_M               GVALAESLGAATFLETGPSAGLGTSV--------------ALLAKGRPEV
Mb1692|M.bovis_AF2122/97            GVGLAESLGARVFVEVGPGAGLEASV--------------ALLARDRPEV
Rv1664|M.tuberculosis_H37Rv         GVGLAESLGARVFVEVGPGAGLEASV--------------ALLARDRPEV
MAV_3107|M.avium_104                GVRLAESQGAGVFLEVGPGAALTAAVDQSLSTEGAT--AIATLPKDRPET
MLBr_00135|M.leprae_Br4923          SARHLQTLGATHFIESGPSSGLMGAIEQSLAPAEAV--VVSMMGKDRPEL
MAB_0939|M.abscessus_ATCC_1997      SVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPRAIVSLRKGVEDR
Mvan_0269|M.vanbaalenii_PYR-1       SVRTVAALGCSVLMEIGPQPVLTGSAVQVWPEHLAAPRAIVSLRKGVSDR
Mflv_0405|M.gilvum_PYR-GCK          SVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIASLRKGVADR
MSMEG_0408|M.smegmatis_MC2_155      SVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVADR
TH_4458|M.thermoresistible__bu      AVRRLLGRGHDAFLEISAHPMLLSAVQEDAADLGRSCTTLVSMRRGECGR
                                    ..      *   ::* .. . *  :                 : :.    

MUL_1655|M.ulcerans_Agy99           ESLLTAMGQLYVDGADLDWRAAFAGLRARTVTLPTYSFARQRFWLG----
MMAR_2473|M.marinum_M               ESLLTAMGQLYVDGADLDWRAAFAGLRARTVTLPTYSFARQRFWLG----
Mb1692|M.bovis_AF2122/97            ESVLAGVGRLFAEGVAVDWSSVFAGLGGRRVELPTYGFARQRFWLG----
Rv1664|M.tuberculosis_H37Rv         ESVLAGVGRLFAEGVAVDWSSVFAGLGGRRVELPTYGFARQRFWLG----
MAV_3107|M.avium_104                ESALHAAGHLFTRGHRLDWAGVFAGLPARRVDLPTYAFARERFWLGGASL
MLBr_00135|M.leprae_Br4923          ASVLGAAGQLFATGMPVEWPAVFAGSSRRRVTLPTYAFQRRRFWETPG--
MAB_0939|M.abscessus_ATCC_1997      RQIADALASAYVSGHRPNFAALQR-HPRRTVELPTYPFQRRRFWPKSSG-
Mvan_0269|M.vanbaalenii_PYR-1       RQITEALAAAYVGGHRPDFGALYR-RPGRAVALPTYPFQRRRFWPKTSG-
Mflv_0405|M.gilvum_PYR-GCK          RQIADALAAAYIGGHKPDFAALHE-QRGVRLELPTYPFQRRRFWPKSAG-
MSMEG_0408|M.smegmatis_MC2_155      RQIADALASAYVGGHRPDFAAVHR-QPRRPVELPTYPFQRRRFWPKASS-
TH_4458|M.thermoresistible__bu      DVLMTSLAALYASGHAVDWARVHP-HGSHCTAAPTYPWQRQRFWLDIDR-
                                         . .  :  *   ::              *** : *.***      

MUL_1655|M.ulcerans_Agy99           ----EGAGRKAD----------SSDESGLRPRLDSVDS------------
MMAR_2473|M.marinum_M               ----EGAGRKAD----------SSDESGLRPRLDSVDS------------
Mb1692|M.bovis_AF2122/97            ---DNGELSVDQ----------TGKDAGAIARLQSLAP------------
Rv1664|M.tuberculosis_H37Rv         ---DNGELSVDQ----------TGKDAGAIARLQSLAP------------
MAV_3107|M.avium_104                AGAPAGAAPVGG----------GTRAPELAHRLHALPR------------
MLBr_00135|M.leprae_Br4923          ---TDGTASVSG----------LGLGSTEHALLGAVVERPDSGGVVLTGR
MAB_0939|M.abscessus_ATCC_1997      TAIEGGGGLPSG--ILGRGEDLASGDSVYISRLSVRSQPWLSDHVIYG--
Mvan_0269|M.vanbaalenii_PYR-1       ITTDG--PAVSG--ILGSAKDLASGDTVYTSRWSVRSQPWLADHVIYG--
Mflv_0405|M.gilvum_PYR-GCK          MAIDGRVGASAGSGILGSGKDLASGDSVYTSRLSVKTQPWLSDHVIYG--
MSMEG_0408|M.smegmatis_MC2_155      IAVDGG-TAASG--ILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYG--
TH_4458|M.thermoresistible__bu      --CDTGDGAGTG---------GTAERTVVPAPLPAPSAS-----------
                                                              .                       

MUL_1655|M.ulcerans_Agy99           ---------------------------------KERFRQLVDLVCLHAAI
MMAR_2473|M.marinum_M               ---------------------------------KERFRQLVDLVCLHAAI
Mb1692|M.bovis_AF2122/97            ---------------------------------PELQRQLVELVCFHAAI
Rv1664|M.tuberculosis_H37Rv         ---------------------------------PELQRQLVELVCFHAAI
MAV_3107|M.avium_104                ---------------------------------DEQQRVLRELVCEHAAA
MLBr_00135|M.leprae_Br4923          LSLANQPWLADHVIGGVVLFPGAGFVELVIRAGDEVGCAGVEELVLAAPL
MAB_0939|M.abscessus_ATCC_1997      ------------------TVVVPGATYAAMALAAVGTPARAKDVFFYEPI
Mvan_0269|M.vanbaalenii_PYR-1       ------------------TVVVPGATYAAMALAAVGTPARVKDVFFYEPI
Mflv_0405|M.gilvum_PYR-GCK          ------------------TVVVPGATYAAMALAAVGTPAHAKDVFFYEPI
MSMEG_0408|M.smegmatis_MC2_155      ------------------TVVVPGATYAAMALAAVGTPARLKDVFFYEPI
TH_4458|M.thermoresistible__bu      --------------------AAPTVDEVLLCADQRERRELLESYLRDRVA
                                                                             .        

MUL_1655|M.ulcerans_Agy99           ATGHSNSHQIDAERAFQGLG------------------------------
MMAR_2473|M.marinum_M               VTGHSNSHQIDAERAFQDLG------------------------------
Mb1692|M.bovis_AF2122/97            VLGRKSSHDIDPECAFQDLG------------------------------
Rv1664|M.tuberculosis_H37Rv         VLGRKSSHDIDPECAFQDLG------------------------------
MAV_3107|M.avium_104                VLGHPGGDAIDPDRAFADLG------------------------------
MLBr_00135|M.leprae_Br4923          VLHPGSGVQVQVVVAAADESSRRAVSVYSRGDQSHGGWLLNAEGLLEVDA
MAB_0939|M.abscessus_ATCC_1997      ILPEKSSREVQLTLHPLEDGSGSKFQVHSRPYGERDVDWSLNAEGTVVTG
Mvan_0269|M.vanbaalenii_PYR-1       ILPEKASREVQLTLHPSEDG-GQKFQVHSREYGERGTEWSLNAEGTVASG
Mflv_0405|M.gilvum_PYR-GCK          ILPEKSSREVQLTVHPSVDG-ESKFQVHSRPYGERGAEWALNAEGVVASG
MSMEG_0408|M.smegmatis_MC2_155      ILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTA
TH_4458|M.thermoresistible__bu      AELGVLPPLLDVAAPLSTLG------------------------------
                                             ::        .                              

MUL_1655|M.ulcerans_Agy99           -------------------------------------FESMTGVELRNR-
MMAR_2473|M.marinum_M               -------------------------------------FESMTGVELRNR-
Mb1692|M.bovis_AF2122/97            -------------------------------------FDSMSGVELRNR-
Rv1664|M.tuberculosis_H37Rv         -------------------------------------FDSMSGVELRNR-
MAV_3107|M.avium_104                -------------------------------------FDSLIGVELRNR-
MLBr_00135|M.leprae_Br4923          AEATVDLSLWPPEGAESVDISDAYPQLAERGYAYGPAFQGLVAIWRRGSE
MAB_0939|M.abscessus_ATCC_1997      IGDDAEPAPE----AAEPAEPVDAAIERMERMRPMELFEIFADLELAWGP
Mvan_0269|M.vanbaalenii_PYR-1       VDENPQ---------AEPSGPVDEAIERLNRMRPQDLFETFADMELAWGP
Mflv_0405|M.gilvum_PYR-GCK          VGDSPAAAG-------DLEDPVDEAIERLNRMRPQELFETFADLELAWGP
MSMEG_0408|M.smegmatis_MC2_155      GSDPDAAAD-------EQSDPVDEVIERLERMRPQDLFETFADLELAWGP
TH_4458|M.thermoresistible__bu      -------------------------------------IDSLTAAELRAR-
                                                                         :: :         

MUL_1655|M.ulcerans_Agy99           ----------------------LRAVT---GLALSRT-------------
MMAR_2473|M.marinum_M               ----------------------LRAVT---GLALSRT-------------
Mb1692|M.bovis_AF2122/97            ----------------------LQMAIGLPGLSLPRT-------------
Rv1664|M.tuberculosis_H37Rv         ----------------------LQMAIGLPGLSLPRT-------------
MAV_3107|M.avium_104                ----------------------LTTHT---GTALSRT-------------
MLBr_00135|M.leprae_Br4923          LFAEVVAPTGVVVDGMGMHPALLDAVLHALGLAIENTQATTEMRLPFCWR
MAB_0939|M.abscessus_ATCC_1997      TWSG-----------------SLKSLWLGEGEAIGDVLVGEELAEQLGTE
Mvan_0269|M.vanbaalenii_PYR-1       TWSG-----------------SLKSLWLGEGEAIGDILVGEELAEQLGTE
Mflv_0405|M.gilvum_PYR-GCK          TWSG-----------------SLKSLWLGEGEAIGDILVGAELAEQLGTE
MSMEG_0408|M.smegmatis_MC2_155      TWSG-----------------SLKSLWLGDGEAVGDILVGAELAEQLGSE
TH_4458|M.thermoresistible__bu      -------------------------VERDLGIVIPVA-------------
                                                                  *  :                

MUL_1655|M.ulcerans_Agy99           -------------IIFDYTTPMALARHLDE--------------------
MMAR_2473|M.marinum_M               -------------IIFDYPTPMALARHLDE--------------------
Mb1692|M.bovis_AF2122/97            -------------LIFDYPTASALAECLG---------------------
Rv1664|M.tuberculosis_H37Rv         -------------LIFDYPTASALAECLG---------------------
MAV_3107|M.avium_104                -------------LIFDYPTPAALADHLRQ--------------------
MLBr_00135|M.leprae_Br4923          GVSLHAGGAGRVRARFTSAGADAIAVDIADSAGLPVL-------------
MAB_0939|M.abscessus_ATCC_1997      PMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLKEKMPRRF
Mvan_0269|M.vanbaalenii_PYR-1       PMHPVLMDLCTGVAFPAFPALLAAEQGVSDLFLPLRYGQVTLRDKMPRRF
Mflv_0405|M.gilvum_PYR-GCK          PMHPVLMDLCTGVAFPAFPALLAAEQGVNDLYLPLRYGQVSLQEKMPRRF
MSMEG_0408|M.smegmatis_MC2_155      PMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLAEKMPRRF
TH_4458|M.thermoresistible__bu      -------------QLLNGPSVSDLAEWIST--------------------
                                                      .        :                      

MUL_1655|M.ulcerans_Agy99           ---------------------------QLSGGNHEESDDDKIWSVLRT--
MMAR_2473|M.marinum_M               ---------------------------QLSGGNHEESDDDKIWSVLRT--
Mb1692|M.bovis_AF2122/97            ---------------------------QLLGGQHESSDDESIWQLLKN--
Rv1664|M.tuberculosis_H37Rv         ---------------------------QLLGGQHESSDDESIWQLLKN--
MAV_3107|M.avium_104                ---------------------------QLLHDEDPESDDERIWSALRR--
MLBr_00135|M.leprae_Br4923          --------TVRSLVTRAMTAEQLRTAVTAAGGALEQGPMDLVWSPIPLSS
MAB_0939|M.abscessus_ATCC_1997      YCRARWHESPLDSETQVFDLDYLDRDGRHLGGIREFTVKRAPREALLRGL
Mvan_0269|M.vanbaalenii_PYR-1       YCRATWHTSELDSETQVFDLDFLDRDGRHLGGIREFTVKRAPREALLRGL
Mflv_0405|M.gilvum_PYR-GCK          YCRATWHEAPLDSETQVFDLEYLDRDGRHLGGVREFTVKRAPREALLRGL
MSMEG_0408|M.smegmatis_MC2_155      YCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGL
TH_4458|M.thermoresistible__bu      ----------------------------TMVGFGSTTPEPESAGVPGR--
                                                                   .                  

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          DGHGGGLPSVVSWADYCAGRGN----------------------------
MAB_0939|M.abscessus_ATCC_1997      GGDATRLLYTLGWHEVAVPPVAGEGEESAASIGTWLIAGFDELAAKVPGC
Mvan_0269|M.vanbaalenii_PYR-1       GGDATRLLYTLGWHEVPAPASG-----DAALNGNWLIAGFDELAAGVPGC
Mflv_0405|M.gilvum_PYR-GCK          GGDATRLLYTLGWHEVPVPESG----DGAAPQGTWLIGGFDELAVSVPGC
MSMEG_0408|M.smegmatis_MC2_155      GGDATRLLYTLGWHEVPPPPSA------DDAVGTWLIAGFDELAAKVPGC
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           ----------------------------IPVRELRRS-------------
MMAR_2473|M.marinum_M               ----------------------------IPVRELRRS-------------
Mb1692|M.bovis_AF2122/97            ----------------------------IPIHQLRRT-------------
Rv1664|M.tuberculosis_H37Rv         ----------------------------IPIHQLRRT-------------
MAV_3107|M.avium_104                ----------------------------IPLRELRRT-------------
MLBr_00135|M.leprae_Br4923          -------------------------DTGVVVWEFGSASAGAQAPVDSVAA
MAB_0939|M.abscessus_ATCC_1997      IPLNRETDPELLGEVLVAAKERGVPFSGVVWRAAGPGATES--TTESAAR
Mvan_0269|M.vanbaalenii_PYR-1       IPFDRSTDPEPLGQLLAQAHERGIGFSGVVWRAAAPSADES--STAMAAR
Mflv_0405|M.gilvum_PYR-GCK          IPADR-TNPESLRQLLTDAHGRGLPFSGVVWRAARSDGDES--DAEVAAR
MSMEG_0408|M.smegmatis_MC2_155      VPIDRNTDLQVLGEVLSQAHARGAGFSGVVWRCATPGRKESGSASAESAR
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           ------GMLDKLLLLAG-----QDER------PAPDAAVSDDVIDSLSPE
MMAR_2473|M.marinum_M               ------GMLDKLLLLAG-----QDES------PAPDAAVSDDVIDSLSPE
Mb1692|M.bovis_AF2122/97            ------GLLDKLLLLAG-----QPEE------SLAGRTVSDEVIDSLSPE
Rv1664|M.tuberculosis_H37Rv         ------GLLDKLLLLAG-----QPEE------SLAGRTVSDEVIDSLSPE
MAV_3107|M.avium_104                ------GLLDKLLLLAG-----MPET------ATTDAKISDADIDSLSPD
MLBr_00135|M.leprae_Br4923          VYSATHAALQVLQFWFG-----QDRAGTLVVLTRGAVGLVGEGISDLAAA
MAB_0939|M.abscessus_ATCC_1997      LEGEIAHLLSAVHTVQNSAQNGVKLPGGLWIVTERAVATESGEPVDPVQA
Mvan_0269|M.vanbaalenii_PYR-1       IETEIADLLSAVHTVQN---GAVKLPGGLWIVTERAVATESGEPVDPVQA
Mflv_0405|M.gilvum_PYR-GCK          LEAEIAELLGAVHTVQG---GEVKLPGGLWIVTERAVATESGEPVDPVQA
MSMEG_0408|M.smegmatis_MC2_155      LEAEITNLLSAVHAAQG---PSVKLPGGLWIVTEHGVACESGEPVDPVQA
TH_4458|M.thermoresistible__bu      ------SRPPDGAVASG------SGDGGRWIELLNQMPEVSDDTVDELLR
                                                    .                       .    .    

MUL_1655|M.ulcerans_Agy99           ALVAMALDSEDDDPD-----------------------------------
MMAR_2473|M.marinum_M               ALVAMALDSEDDDPD-----------------------------------
Mb1692|M.bovis_AF2122/97            ALIGLALDEDENDIR-----------------------------------
Rv1664|M.tuberculosis_H37Rv         ALIGLALDEDENDIR-----------------------------------
MAV_3107|M.avium_104                ALIAMALNSADDDEAE----------------------------------
MLBr_00135|M.leprae_Br4923          AVWGMVRSAQSEHSGKIVLID--------TDSAVDVAVLADLGESQLLVR
MAB_0939|M.abscessus_ATCC_1997      ALWGFGRTTINEEPALRAKLVDGDGSPEAVQALARLLVTP-VDEPEIAVR
Mvan_0269|M.vanbaalenii_PYR-1       ALWGFGRTTINEEPALRCRLVDVDGSPEAVLALAGLLAAP-VDEPELAVR
Mflv_0405|M.gilvum_PYR-GCK          ALWGFGRTAINEEPALRCRLVDCDGSPQAVQALAALLSTP-VDEPELAVR
MSMEG_0408|M.smegmatis_MC2_155      ALWGFGRTTINEEPALHCRLVDCDGSSEAVDLLAALLAAPGIQEPEIAVR
TH_4458|M.thermoresistible__bu      QLLAAGENHDDTQLH-----------------------------------
                                     : .      . .                                     

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          CNTVHAARLSPAPQLLALPVGESMWRLAADGGGTLEDLVIQPCPEVQAPL
MAB_0939|M.abscessus_ATCC_1997      QGKLLASRLLPWSRTGHLTVPRGSDYVLAPTERGAIDNLRITEKEVPAP-
Mvan_0269|M.vanbaalenii_PYR-1       QGKLLASRLLPWARSGHLTVPRSADYVLAPTERGAIDNLRLTETDVAPP-
Mflv_0405|M.gilvum_PYR-GCK          QGKLLASRLLPWSRSGHLTVPRGGDYVLAPTERGAIDNLRLTDSEVPPP-
MSMEG_0408|M.smegmatis_MC2_155      QGKLLASRLLPWARSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVPEP-
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          QAGHMRVAVAAVGVNFRDVVAALGMYPGQAPPLGAEGAGVVIEIGPEVTG
MAB_0939|M.abscessus_ATCC_1997      DEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGIVTQLGEGVTG
Mvan_0269|M.vanbaalenii_PYR-1       AEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGSGVTG
Mflv_0405|M.gilvum_PYR-GCK          AEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGEGVTG
MSMEG_0408|M.smegmatis_MC2_155      DEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSG
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          VAVGDAVMGFLGGAGPLAV-VHQQLITQMPQGWSLAEAAAVPVVFLTALF
MAB_0939|M.abscessus_ATCC_1997      VEVGQRVYGSMQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVR-
Mvan_0269|M.vanbaalenii_PYR-1       LEVGQRVYGFMQGAFASRFNVPAQLLAPIPDGIGAVDAATIPAAALTAR-
Mflv_0405|M.gilvum_PYR-GCK          LDVGQRVYGSMQGAFASRFNVPGQFLAPIPDGVSAVEAATIPAAALTVR-
MSMEG_0408|M.smegmatis_MC2_155      LEIGQRVYGSMQGAFASRFNVPAQFLAPIPDGIGAVEAATIPAAALTVR-
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          GLADLAGIRAGESVLIHAGTGGVGMAAVQFARHWGVEIFVTASRGKWDTL
MAB_0939|M.abscessus_ATCC_1997      LSFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQFGAEVFATASTFKRATL
Mvan_0269|M.vanbaalenii_PYR-1       LAFDWAQLKPGDRVLIHAASGGVGLAAIQMAQQHGAVVFATASTYKRATL
Mflv_0405|M.gilvum_PYR-GCK          LSFDWAQVKSGDKVLIHAASGGVGLAAVQMAQQCGAEVYATASTFKRATL
MSMEG_0408|M.smegmatis_MC2_155      LAFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQSGAEVFATASTFKRSTL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          RDMGFDDDHIGDSRTLEFEEKFLAVTDGRGVDVVLDSLAGD-FVDASLRL
MAB_0939|M.abscessus_ATCC_1997      RKLG--VKYVYDSRTTDFADQILADTDGAGVDVVLNSLTSEGFIEATLRA
Mvan_0269|M.vanbaalenii_PYR-1       RKLG--VDHVYDSRTTEFADQILADTDGEGVDVVLNSLTNEGFIEATVRA
Mflv_0405|M.gilvum_PYR-GCK          RKLG--VKHVYDSRTTDFAEQILADTDGAGVDVVLNSLTSEGFIEATLRA
MSMEG_0408|M.smegmatis_MC2_155      RRLG--VKYVYDSRTTDFADQILADTNGAGVDVVLNSLTSAGFVEATLKA
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          LVRGGRFLEMGKTDIRDAQEIAANYPGVQYRAFDLS---EAGPVRMQEML
MAB_0939|M.abscessus_ATCC_1997      TAKNGRFAEIAKRDIWTTEQMAQSRPDIAYEIVALDTVMFQEPDRIRVLL
Mvan_0269|M.vanbaalenii_PYR-1       TAQNGRFAEIAKRDIWTPEQMAAARPDIAYEIVALDTVTLLEPERIRGLL
Mflv_0405|M.gilvum_PYR-GCK          TAQHGRFAEIAKRDIWTVEQMAAARPDLAYEIVALDTVMFTEPDRIRDLL
MSMEG_0408|M.smegmatis_MC2_155      TAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          CEVRELFDTQ------VLHRLPVTSWDVRCAPAAFRFMSQARHIGKVVLT
MAB_0939|M.abscessus_ATCC_1997      TEVSEGLAKG------EWTPLPAEIYPLTEARTAFRRMQQARHIGKIVCQ
Mvan_0269|M.vanbaalenii_PYR-1       GEVSDGLGKADGSSRAEWVPLPAEIYPLTEARAAFRRMQQARHVGKIVLQ
Mflv_0405|M.gilvum_PYR-GCK          TEVSAGLRDG------AWTPLPAEVYPLTEARAAFRRMQQARHIGKIVVQ
MSMEG_0408|M.smegmatis_MC2_155      TEVSDGMARG------EWTPLPAEIYPITEARSAFRRMQQARHIGKIVLQ
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          MPSALADGLAEGTVLITGASGAIGGVLARHMVSAYGVRHLVLASRRGDRA
MAB_0939|M.abscessus_ATCC_1997      MPNPLAP-RPDRTYLITGGLGAIG-LHTAAYLAQLGAGDIVLTSRRAPDT
Mvan_0269|M.vanbaalenii_PYR-1       MPKPLQP-RADRSYLITGGLGAIG-LHTAAYLAQLGAGDLVLTSRRAPDA
Mflv_0405|M.gilvum_PYR-GCK          IPNPLQP-QPDRSYLITGGLGAIG-LHTAGYLAQLGAGDIVLTSRRAPDA
MSMEG_0408|M.smegmatis_MC2_155      VPKPLQP-QQDRSYLITGGLGAIG-LHTAAYLAQLGAGDIVLTSRRDPDE
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          EGAVELAAELVGAGAKIQVVACDVADNDAVRGLFAQLSREFPPVRGVIHA
MAB_0939|M.abscessus_ATCC_1997      DAQRVIGEITERSKTRIHVFTADVGAESEVAGLLERIRAELPPLAGVAHL
Mvan_0269|M.vanbaalenii_PYR-1       DARRAIEEITERYKCRVHTFCADVGDESQVAELLARIRAELPPLAGVAHL
Mflv_0405|M.gilvum_PYR-GCK          AAQQAIADIADRTKARLHVFTADVGVEADVAALLERIRAELPPLAGVAHL
MSMEG_0408|M.smegmatis_MC2_155      SAQRAIDEITERHKCRIHTYAADVGDEAQVADLLARIRAELPPLAGIAHL
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          AGVLDDGAITSLTPDRVDTVLRAKVDAAWNLHEATRDLDLLMFVLCSSIA
MAB_0939|M.abscessus_ATCC_1997      AGVLDDALLGQQSVERFRTTLAPKAFGAEYLDRLTKGDDLDFFIVSSSVS
Mvan_0269|M.vanbaalenii_PYR-1       AGVLDDALLSQQSLERFRTTLAPKAFGACHLDRLTAGDDLDFFIMSSSVS
Mflv_0405|M.gilvum_PYR-GCK          AGVLDDALLSQQSVERFRTALAPKAFGAVHLDRLTRVDDLDFFLVSSSVS
MSMEG_0408|M.smegmatis_MC2_155      AGVLDDALLSAQNPERFRTTLAPKAYGASHLDRLTRDDDLDFFIVSSSVS
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          ATVGSPGQGNYSAANAFLDGLAAYRQAAGLAGTSLAWGLWEQPGGMNAHL
MAB_0939|M.abscessus_ATCC_1997      SLFGSPGQSNYATANALLDGLIAQRRAQGLPATGINFGPWGQGGMASSEA
Mvan_0269|M.vanbaalenii_PYR-1       SLFGSPGQANYATANALLDGLTAHRRARGLPATGVNFGPWAQGGMASSEA
Mflv_0405|M.gilvum_PYR-GCK          SLFGSPGQSNYATANAFLDGLVAQRRAQGLPATGVNFGPWARGGMASSEA
MSMEG_0408|M.smegmatis_MC2_155      SLFGSPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASSEA
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          SSRDLARISRSGLAPMNPAQALELFDAALVIDHPFMVTALLDRAALDAQA
MAB_0939|M.abscessus_ATCC_1997      ATAN---ISAQGLIPLDPSAALAALAEVVANGTG-QATILKANWQRAAKV
Mvan_0269|M.vanbaalenii_PYR-1       ATAN---IGAQGLVPLEPSAALGALAEVLANGTG-QAAVLKANWQRAAKV
Mflv_0405|M.gilvum_PYR-GCK          AAAN---ISAQGLIPLEPSAALTAMAEVVANGTA-QATVLKANWQRAAKV
MSMEG_0408|M.smegmatis_MC2_155      ATAN---ITAQGLIPLDPSAALHALAEVIANGSG-QATVLKANWQRAAKV
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          QAGALPPLFSRLVRRSRRRQIEDPGDATQSKLALVQRLQGLAANRQLELL
MAB_0939|M.abscessus_ATCC_1997      LGSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGFVTEFLQREV
Mvan_0269|M.vanbaalenii_PYR-1       LGSSRPPILDLVLPRPEGEVAGDSELLRQLQEIPVAQRAGFVTEFLQREV
Mflv_0405|M.gilvum_PYR-GCK          LGSSRPPILDLVLPSAVGEITGDSELLKQLQEIPVPQRAGFVTEFLQKEV
MSMEG_0408|M.smegmatis_MC2_155      LGSARPPILDLVLPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREV
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          VGVVCLQAAAVLGRPSPEDIDPNTKFQDLGFDSLTAVELRNRLKSATG--
MAB_0939|M.abscessus_ATCC_1997      QNFLRLAQPP----------AATSRFLDLGTDSLMAIELRNRLHSQFGGK
Mvan_0269|M.vanbaalenii_PYR-1       QNFLRLAQPP----------AATSRFLDLGTDSLMAIELRNRLHSQFGGA
Mflv_0405|M.gilvum_PYR-GCK          QNFLRLAQPP----------AATSRFLDLGTDSLMAIELRNRLHSQFGGA
MSMEG_0408|M.smegmatis_MC2_155      QNFLRLASPP----------AASSRFLDLGTDSLMAIELRNRLHSQFGGK
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           --------------------------------------------------
MMAR_2473|M.marinum_M               --------------------------------------------------
Mb1692|M.bovis_AF2122/97            --------------------------------------------------
Rv1664|M.tuberculosis_H37Rv         --------------------------------------------------
MAV_3107|M.avium_104                --------------------------------------------------
MLBr_00135|M.leprae_Br4923          LTLPPTVIFDHPTPTAVAEYVAQQMLKSRPAESGDETSQAVEPKVEEVSV
MAB_0939|M.abscessus_ATCC_1997      FTINATAVFDYPTIGGLAEYLVGQLPDADAESAEAPPAVESAEAESGAGP
Mvan_0269|M.vanbaalenii_PYR-1       FTINATAVFDYPTIGGLAEYLVGQLPDSDAAAGETPATETSPIDHNHPDR
Mflv_0405|M.gilvum_PYR-GCK          FTINATAVFDYPTIGGLAEYLVAQLPD-----AETPQAAPQSESEPGPDV
MSMEG_0408|M.smegmatis_MC2_155      FTINATAVFDYPTIGGLAEYLVGQLPD-----AEAPETA-----------
TH_4458|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

MUL_1655|M.ulcerans_Agy99           ------------
MMAR_2473|M.marinum_M               ------------
Mb1692|M.bovis_AF2122/97            ------------
Rv1664|M.tuberculosis_H37Rv         ------------
MAV_3107|M.avium_104                ------------
MLBr_00135|M.leprae_Br4923          HA----------
MAB_0939|M.abscessus_ATCC_1997      AAASDAVSELKE
Mvan_0269|M.vanbaalenii_PYR-1       EADSPG------
Mflv_0405|M.gilvum_PYR-GCK          TE----------
MSMEG_0408|M.smegmatis_MC2_155      ------------
TH_4458|M.thermoresistible__bu      ------------