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PVARTPDLQRRRQLLDALVEDFATHGVGDRSLRDVAAAVGTSHRMLLHHFGSRDNLLVAVVEEVERRQMS LLPELPTSPAESFTAMWADVRRPELRQLERLFFECYSRAAQGEKRFAQMVPRAVYGWLAEANAVTEGSAD PALVRLGLAVIRGLLLDLVATDDDAGVDAAARAFAQLLSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1645 | - | - | 100% (181) | transcriptional regulatory protein |
| M. marinum M | MMAR_0108 | - | 1e-17 | 34.34% (166) | transcriptional regulatory protein |
| M. marinum M | MMAR_1597 | - | 7e-17 | 32.93% (167) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1251c | - | 1e-06 | 35.62% (73) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_0973 | - | 1e-05 | 38.46% (52) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1219c | - | 1e-06 | 35.62% (73) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_00949 | - | 1e-05 | 33.33% (66) | hypothetical protein MLBr_00949 |
| M. abscessus ATCC 19977 | MAB_3199c | - | 3e-08 | 47.37% (57) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3916 | - | 1e-69 | 72.47% (178) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4070 | - | 4e-24 | 37.64% (178) | transcriptional regulator, TetR family protein, putative |
| M. thermoresistible (build 8) | TH_4015 | - | 8e-09 | 27.57% (185) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1881 | - | 1e-96 | 98.88% (179) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4792 | - | 3e-05 | 34.38% (64) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1645|M.marinum_M ----------------------------MPVARTPDLQRRRQLLDALVED
MUL_1881|M.ulcerans_Agy99 ------------------------------MARTPDLQRRRQLLDALVED
MAV_3916|M.avium_104 ------------------------------MARTPDRQRRRELLDGLIAE
MSMEG_4070|M.smegmatis_MC2_155 -----------------------------MAGRPVDHQRRAELLDAIVDY
Mb1251c|M.bovis_AF2122/97 -------------------------------MRSADLTAHARIREAAIEQ
Rv1219c|M.tuberculosis_H37Rv -------------------------------MRSADLTAHARIREAAIEQ
MAB_3199c|M.abscessus_ATCC_199 -------------------------MTRAGTKGMPRAERERQILDAACQE
TH_4015|M.thermoresistible__bu VVPRRRVDNGSNEQGVASDATGGDRMNRPLPPTARGRRSRRALLDAAKEV
Mvan_4792|M.vanbaalenii_PYR-1 ---------------------------------MPAEDPRQRAIDAAVEL
MLBr_00949|M.leprae_Br4923 -----------------------MTTSARTHRWAKTGAIQRRILDAAIEV
Mflv_0973|M.gilvum_PYR-GCK ---------------------------MSGDSTRAGGPTRRRLIDVAIEL
. :
MMAR_1645|M.marinum_M FATHGVGDRSLRDVAAAVGTSHRMLLHHFGSRDNLLVAVVEEVERRQ---
MUL_1881|M.ulcerans_Agy99 FATHGVGDRSLRDVAAAVGTSHRMLLHHFGSRDNLLVAVVEEVERRQ---
MAV_3916|M.avium_104 FAAGGIGDRSLRRVAEAVGTSHRMLLHHFGSREGLLLAIVEEVERRQ---
MSMEG_4070|M.smegmatis_MC2_155 AVEHGFSELTWRPVAAALGVTSNTLVHHFGTKEQMFQAVLERLRARL---
Mb1251c|M.bovis_AF2122/97 FGRHGFG-VGLRAIAEAAGVSAALVIHHFGSKEGLRKACDDFVAEEI---
Rv1219c|M.tuberculosis_H37Rv FGRHGFG-VGLRAIAEAAGVSAALVIHHFGSKEGLRKACDDFVAEEI---
MAB_3199c|M.abscessus_ATCC_199 FGRSGYVGMSLAAVAAAVGVSKPMVLAYFGSKEQLYIACVERAGATVGDH
TH_4015|M.thermoresistible__bu FARDGFADARITDIADAAGTAHGSFYRYFDSKEEIFIELLRELVEEL---
Mvan_4792|M.vanbaalenii_PYR-1 FHREGFGAVGIDRLTTSIGMSKRTLYKYFDSKDDLLLAVLDSCEGMA---
MLBr_00949|M.leprae_Br4923 FATRSFTTATMTDAMTGSGAIIGSIYHHFGGKRKLFLAIFEQMGRQR---
Mflv_0973|M.gilvum_PYR-GCK FKRYSVAGTSLQMISDELGLTKSAIYHHFRTRDELLTAVMEPLIAEVA--
. * . :* : :
MMAR_1645|M.marinum_M ---------------MSLLPELP---TSPAESFTAMWADVRRPELRQLER
MUL_1881|M.ulcerans_Agy99 ---------------MSLLPELP---TSPAESFTAMWADVRRPELRQLER
MAV_3916|M.avium_104 ---------------MRVLTELP---REPAEGFAAMWADLRRPELREFER
MSMEG_4070|M.smegmatis_MC2_155 ---------------LVATDELLGSRTDLASAARLAWELSSDPKRGPEFR
Mb1251c|M.bovis_AF2122/97 ---------------RSSKAAALK--SNDPTTWLAQMAEIES--YAPLMA
Rv1219c|M.tuberculosis_H37Rv ---------------RSSKAAALK--SNDPTTWLAQMAEIES--YAPLMA
MAB_3199c|M.abscessus_ATCC_199 IEAAMTAAPPTLALPRAVLQAIFQALAPRPSDWLVIWDQTLPEGSEALAA
TH_4015|M.thermoresistible__bu ---------------RQPVRTDAGTEPKNPYERILRANRTYLEAYRANRA
Mvan_4792|M.vanbaalenii_PYR-1 ---------------LRDLPDEDDDSSPRDRILAVFDAQAKYCTDPDFAG
MLBr_00949|M.leprae_Br4923 --------------------------RPPHRRGDATSGPIRPSGDRSAAG
Mflv_0973|M.gilvum_PYR-GCK ---------------EIVDAAEEQRTPHARADHMLVGYASIAARHRTLIP
MMAR_1645|M.marinum_M LFFECYSRAAQGEK------------RFAQMVPRAVYGWLAEA-------
MUL_1881|M.ulcerans_Agy99 LFFECYSRAAQGEK------------RFAQMVPHAVYGWLAEA-------
MAV_3916|M.avium_104 LFFECYSRAAQGEK------------PFARMLPDAVDDWLRQA-------
MSMEG_4070|M.smegmatis_MC2_155 LFFAVYGRALQAPE------------QFTNFLQRVVADWMGSL-------
Mb1251c|M.bovis_AF2122/97 YLVRSMQSGGELAK------------MLWQKMIDNAEEYLDEG-------
Rv1219c|M.tuberculosis_H37Rv YLVRSMQSGGELAK------------MLWQKMIDNAEEYLDEG-------
MAB_3199c|M.abscessus_ATCC_199 ARVARTRLAALAGQGVAAVGSAATQLRDAQDIGVLTQGWMGMVGAMITWW
TH_4015|M.thermoresistible__bu IMIVWEQVASLNEH----------VEQLRREYSDRFAARIERAIIR----
Mvan_4792|M.vanbaalenii_PYR-1 CFFVNIATEFRDPD------------HRAVRIAADHKAKLTQFLVR----
MLBr_00949|M.leprae_Br4923 IRSPRTGPTSRRCG----------------KTGTRPGCCRPET-------
Mflv_0973|M.gilvum_PYR-GCK LLSGDPGVVALLRT--------------RSEWGDLVRRQLALFS------
MMAR_1645|M.marinum_M NAVTEGSADPALVR----LGLAVIRGLLLDLVATDDDA------------
MUL_1881|M.ulcerans_Agy99 SAVTEGSADPALVR----LGLAVIRGLLLDLVATDDDA------------
MAV_3916|M.avium_104 ETHAGAPFDPAMAR----LGLAVIRGLLLDLVATGDEA------------
MSMEG_4070|M.smegmatis_MC2_155 CKAQGPEVEPAAARQRATLVIATIRGLLLDLLATDDQD------------
Mb1251c|M.bovis_AF2122/97 VRAGTVKPSRDPRARARFLAITGGGGFLLYLQMHENPT------------
Rv1219c|M.tuberculosis_H37Rv VRAGTVKPSRDPRARARFLAITGGGGFLLYLQMHENPT------------
MAB_3199c|M.abscessus_ATCC_199 IRHPEQSAEQMAERASRLIGIIASAGISEAEAPEGGAVPRPGTPVRGSGS
TH_4015|M.thermoresistible__bu -WQEAGLADPAIDPRYAAAALSGMLSNFAYRWSVQDAD------------
Mvan_4792|M.vanbaalenii_PYR-1 QARLAGVAAPDDLAEQLTVLHTGAADYALLYGHYPDST------------
MLBr_00949|M.leprae_Br4923 --HLQASRSPVATA------------------------------------
Mflv_0973|M.gilvum_PYR-GCK --EVEPGLGGQVKAALAMSGIASAAGVDYGGDVDDDTLR-----------
MMAR_1645|M.marinum_M ---------------------GVDAAARAFAQLLSR--------------
MUL_1881|M.ulcerans_Agy99 ---------------------GVDAAARAFAQLLSR--------------
MAV_3916|M.avium_104 ---------------------GVDAAARAFVNLLNAGA------------
MSMEG_4070|M.smegmatis_MC2_155 ---------------------RVRDAAEAFLTSL----------------
Mb1251c|M.bovis_AF2122/97 ---------------------DLRAALRDYAHDMVLPSLEVYTEGLLADR
Rv1219c|M.tuberculosis_H37Rv ---------------------DLRAALRDYAHDMVLPSLEVYTEGLLADR
MAB_3199c|M.abscessus_ATCC_199 GQPLNAAFDLFGRRWAILVVWELRSGTKTLPELKAEMGDASSSVLATRLK
TH_4015|M.thermoresistible__bu --------------------YDLDTAAEQLSLLWANALGVRVPAHHEPAH
Mvan_4792|M.vanbaalenii_PYR-1 -----------------------RTAVAALLTAAGL--------------
MLBr_00949|M.leprae_Br4923 --------------------------------------------------
Mflv_0973|M.gilvum_PYR-GCK --------------------DQLIAAGRRALGLRNSRTGAVTARR-----
MMAR_1645|M.marinum_M -------------------------------------------
MUL_1881|M.ulcerans_Agy99 -------------------------------------------
MAV_3916|M.avium_104 -------------------------------------------
MSMEG_4070|M.smegmatis_MC2_155 -------------------------------------------
Mb1251c|M.bovis_AF2122/97 AMYEAFLAEAQQGEAHVG-------------------------
Rv1219c|M.tuberculosis_H37Rv AMYEAFLAEAQQGEAHVG-------------------------
MAB_3199c|M.abscessus_ATCC_199 ELTAAHIVRNQDGQYSLTTVGKGLLVALAPLHLWAKAWSASVR
TH_4015|M.thermoresistible__bu A------------------------------------------
Mvan_4792|M.vanbaalenii_PYR-1 -------------------------------------------
MLBr_00949|M.leprae_Br4923 -------------------------------------------
Mflv_0973|M.gilvum_PYR-GCK -------------------------------------------