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VRAIAMVSNDHSGERVDGRRLRYRDRRGEILDAVMAHLLEHGISGMSFRTLAAAAGVSHITLRHHFGTKD ELLVEIFGVIGARVQIPDHFGADDVESLVRKMWQRWTEPQSDRRSRLVFEAYAHAVRSPDEYRAFLDRVV TGWIEIIRYHALLAGCPSDEADTFATLLLAQLRGLQFDFLATGDRVRIGTALESVIDGIHHQRAQWARVA SR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1597 | - | - | 100% (212) | transcriptional regulatory protein |
| M. marinum M | MMAR_0108 | - | 1e-78 | 67.66% (201) | transcriptional regulatory protein |
| M. marinum M | MMAR_1645 | - | 9e-17 | 32.93% (167) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0335 | - | 2e-10 | 28.32% (173) | TetR/AcrR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2327 | - | 3e-05 | 26.97% (178) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0328 | - | 2e-10 | 28.32% (173) | TetR/AcrR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1518 | - | 9e-06 | 47.83% (46) | hypothetical protein MAB_1518 |
| M. avium 104 | MAV_3916 | - | 3e-18 | 32.57% (175) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4070 | - | 1e-23 | 35.56% (180) | transcriptional regulator, TetR family protein, putative |
| M. thermoresistible (build 8) | TH_4019 | - | 8e-09 | 42.86% (63) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1881 | - | 2e-16 | 31.55% (168) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4092 | - | 1e-06 | 35.90% (78) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0335|M.bovis_AF2122/97 -------------------MQQQRTNRDKLLDGALACLRERGYGNTSSRD
Rv0328|M.tuberculosis_H37Rv -------------------MQQQRTNRDKLLDGALACLRERGYGNTSSRD
MAV_3916|M.avium_104 ----------------MA-RTPDRQRRRELLDGLIAEFAAGGIGDRSLRR
MUL_1881|M.ulcerans_Agy99 ----------------MA-RTPDLQRRRQLLDALVEDFATHGVGDRSLRD
MSMEG_4070|M.smegmatis_MC2_155 ----------------MAGRPVDHQRRAELLDAIVDYAVEHGFSELTWRP
MMAR_1597|M.marinum_M MRAIAMVSNDHSGERVDGRRLRYRDRRGEILDAVMAHLLEHGISGMSFRT
TH_4019|M.thermoresistible__bu --------MVDAGETTDGRRARGQRRRAEIIDATLAVVERDGAAGVTHRA
MAB_1518|M.abscessus_ATCC_1997 ---------------METVDPDDLTARARIRDAALREFGDKGYDGATIRG
Mflv_2327|M.gilvum_PYR-GCK ------------MAERWTKERRTEHTRQILLDAAEEVFARKGLTGAALEE
Mvan_4092|M.vanbaalenii_PYR-1 ---------MTTTDATSPRSRAKSDRRGQLIGAAERLIAEHGYLAVRLED
* : .. * .
Mb0335|M.bovis_AF2122/97 IARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRVQEAFDHSRAAGP
Rv0328|M.tuberculosis_H37Rv IARAAGVNIASINYHFGSKDALLDDALGRCFSTWNQRVQEAFDHSRAAGP
MAV_3916|M.avium_104 VAEAVGTSHRMLLHHFGSREGLLLAIVEEVERRQMRVLTELP-----REP
MUL_1881|M.ulcerans_Agy99 VAAAVGTSHRMLLHHFGSRDNLLVAVVEEVERRQMSLLPELP-----TSP
MSMEG_4070|M.smegmatis_MC2_155 VAAALGVTSNTLVHHFGTKEQMFQAVLERLRARLLVATDELLGS--RTDL
MMAR_1597|M.marinum_M LAAAAGVSHITLRHHFGTKDELLVEIFGVIGAR-VQIPDHFG----ADDV
TH_4019|M.thermoresistible__bu VAAEAGIPASLTAYYFATLDDLLVAALSSVADGYTERIREIIE-----RP
MAB_1518|M.abscessus_ATCC_1997 IAARAGVSSGLLRHHFGSKQELRDACDEYLVKTMRDINEQVQANVERGDV
Mflv_2327|M.gilvum_PYR-GCK IADAAGFTRGAIYSQFGAKEKLFLAVVDRQRERFLDGFADVMDS--FHRL
Mvan_4092|M.vanbaalenii_PYR-1 IGAAAGISGPAIYRHFPNKEALLVELLVGISTRLLAGAVEVVDR-AGDDA
:. * * : : .
Mb0335|M.bovis_AF2122/97 AGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAGY-ADV
Rv0328|M.tuberculosis_H37Rv AGQILAVLEATVDSFEQIRPAVYACVESYAPALRSEALRERLAAGY-ADV
MAV_3916|M.avium_104 AEGFAAMWADLRR--PELREFERLFFECYSRAAQGEKPFARMLPDA-VDD
MUL_1881|M.ulcerans_Agy99 AESFTAMWADVRR--PELRQLERLFFECYSRAAQGEKRFAQMVPHA-VYG
MSMEG_4070|M.smegmatis_MC2_155 ASAARLAWELSSD--PKRGPEFRLFFAVYGRALQAPEQFTNFLQRV-VAD
MMAR_1597|M.marinum_M ESLVRKMWQRWTE--PQSDRRSRLVFEAYAHAVRSPDEYRAFLDRV-VTG
TH_4019|M.thermoresistible__bu GDRLRGLAELIVESAGPGRERALAERELSTLAARRP-----ALQPV-ARR
MAB_1518|M.abscessus_ATCC_1997 HYVSARIPVGQYQAYITRALVEGSAGQLFDEMVAMTEGWLAVADQNRAYP
Mflv_2327|M.gilvum_PYR-GCK SDVDIDELAQRWRQLSSGADRAALGYELTLYLLRNPDARASVAAQR-RET
Mvan_4092|M.vanbaalenii_PYR-1 DSALEGLIDFHLDFVFGEPDLIRIQDRDLGNLPPAAKRQVRRKQRQYVEI
Mb0335|M.bovis_AF2122/97 RQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPR
Rv0328|M.tuberculosis_H37Rv RQHSVDLAGAALAGTDIAPPENLSTIVSVLMAVIDGLMIQWIADPSATPR
MAV_3916|M.avium_104 WLRQAETHAGAP-----FDPAMAR----LGLAVIRGLLLDLVATGDEAGV
MUL_1881|M.ulcerans_Agy99 WLAEASAVTEGS-----ADPALVR----LGLAVIRGLLLDLVATDDDAGV
MSMEG_4070|M.smegmatis_MC2_155 WMGSLCKAQGPE-----VEPAAARQRATLVIATIRGLLLDLLATDDQDRV
MMAR_1597|M.marinum_M WIEIIRYHALLAG----CPSDEADTFATLLLAQLRGLQFDFLATGDRVRI
TH_4019|M.thermoresistible__bu WRDNVAELASTLT----DDPQAIA----ALVAASDGLCTAILIDNAPADV
MAB_1518|M.abscessus_ATCC_1997 AAVDVKSRAAVITAMALAVPLLQQHVSRGLGVDIDSPEGDLKMAATLVDV
Mflv_2327|M.gilvum_PYR-GCK IRALGEFISKNVARIGGTLTIEAETLARIVLAANDGVTLDSHIDGEDLYR
Mvan_4092|M.vanbaalenii_PYR-1 WVDVLRRRTPGLTET--DARLMAHAAFGLLNSTPHGVKPGLNKAAEASSR
.
Mb0335|M.bovis_AF2122/97 STEVIRALASIGAVVTSQLR----
Rv0328|M.tuberculosis_H37Rv STEVIRALASIGAVVTSQLR----
MAV_3916|M.avium_104 DAAARAFVNLLNAGA---------
MUL_1881|M.ulcerans_Agy99 DAAARAFAQLLSR-----------
MSMEG_4070|M.smegmatis_MC2_155 RDAAEAFLTSL-------------
MMAR_1597|M.marinum_M GTALESVIDGIHHQRAQWARVASR
TH_4019|M.thermoresistible__bu DFAHGVLRRALGVPAEHQP-----
MAB_1518|M.abscessus_ATCC_1997 YANPLLTPEQAKSAQEDLARRMR-
Mflv_2327|M.gilvum_PYR-GCK PYLQLVMSSVQTPH----------
Mvan_4092|M.vanbaalenii_PYR-1 TVLRTMTVAALTSAGRRA------