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MTTTDATSPRSRAKSDRRGQLIGAAERLIAEHGYLAVRLEDIGAAAGISGPAIYRHFPNKEALLVELLVG ISTRLLAGAVEVVDRAGDDADSALEGLIDFHLDFVFGEPDLIRIQDRDLGNLPPAAKRQVRRKQRQYVEI WVDVLRRRTPGLTETDARLMAHAAFGLLNSTPHGVKPGLNKAAEASSRTVLRTMTVAALTSAGRRA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4092 | - | - | 100% (206) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0360 | - | 3e-26 | 37.80% (164) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3985 | - | 8e-20 | 35.95% (153) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 8e-72 | 69.15% (201) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2551 | - | 3e-89 | 81.95% (205) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2506 | - | 8e-72 | 69.15% (201) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01733 | - | 4e-08 | 26.04% (169) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4541 | - | 6e-60 | 60.10% (198) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3853 | - | 6e-74 | 73.74% (198) | putative regulatory protein |
| M. avium 104 | MAV_1669 | - | 1e-67 | 69.23% (195) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4718 | - | 4e-73 | 73.47% (196) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2795 | - | 2e-12 | 26.19% (168) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3785 | - | 1e-73 | 73.23% (198) | putative regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2534|M.bovis_AF2122/97 --------------------------------------------------
Rv2506|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1669|M.avium_104 --------------------------------------------------
MMAR_3853|M.marinum_M --------------------------------------------------
MUL_3785|M.ulcerans_Agy99 --------------------------------------------------
Mvan_4092|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2551|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4718|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4541|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2795|M.thermoresistible__bu MSAAGSDAHRNGRHRPKNRKALIARASADAFGAQGYHAVSMEEIAARVGI
MLBr_01733|M.leprae_Br4923 --------------------------------------------------
Mb2534|M.bovis_AF2122/97 --------------------------------------------------
Rv2506|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1669|M.avium_104 --------------------------------------------------
MMAR_3853|M.marinum_M --------------------------------------------------
MUL_3785|M.ulcerans_Agy99 --------------------------------------------------
Mvan_4092|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2551|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4718|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4541|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2795|M.thermoresistible__bu SPAALYRHSQGKYDLFRDSVLGLGQLLVDATDFGDDVDPAEDPHGLLAAL
MLBr_01733|M.leprae_Br4923 --------------------------------------------------
Mb2534|M.bovis_AF2122/97 --------------------------------------------------
Rv2506|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1669|M.avium_104 --------------------------------------------------
MMAR_3853|M.marinum_M --------------------------------------------------
MUL_3785|M.ulcerans_Agy99 --------------------------------------------------
Mvan_4092|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2551|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4718|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4541|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2795|M.thermoresistible__bu VDALINVTIANRTAGGLYRWEGRYLREPDRDILERQIQLVNRRLQRPLRV
MLBr_01733|M.leprae_Br4923 --------------------------------------------------
Mb2534|M.bovis_AF2122/97 ------------------------------------------------MT
Rv2506|M.tuberculosis_H37Rv ------------------------------------------------MT
MAV_1669|M.avium_104 --------------------------------------------------
MMAR_3853|M.marinum_M ------------------------------------------------MA
MUL_3785|M.ulcerans_Agy99 ------------------------------------------------MA
Mvan_4092|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2551|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_4718|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4541|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2795|M.thermoresistible__bu MRPELGSRQRWTLTASALSAIGSIADHSAPLSVPGIRSFLASVVEDLLAA
MLBr_01733|M.leprae_Br4923 --------------MTRRSIHTRKPLKWSGCAGQHVRSGKVFDVGRISLS
Mb2534|M.bovis_AF2122/97 ASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIG
Rv2506|M.tuberculosis_H37Rv ASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIG
MAV_1669|M.avium_104 -------------------MKSDRRLQLLSAAERLFAERGFLAVRLEDIG
MMAR_3853|M.marinum_M ASAPDEQTATP---NRRSQQKSDRRLQLLSAAERLFAERGFLAVRLEDIG
MUL_3785|M.ulcerans_Agy99 ASAPDEQTATP---NRRSQQKSDRRLQLLSAAERLFAERGFLAVRLEDIG
Mvan_4092|M.vanbaalenii_PYR-1 -------MTTTDATSPRSRAKSDRRGQLIGAAERLIAEHGYLAVRLEDIG
Mflv_2551|M.gilvum_PYR-GCK -------MAPTEISSPRSRAKSDRRDQLVAAAERLFAEHGYLAVRLEDIG
MSMEG_4718|M.smegmatis_MC2_155 -------MSS---VTRRSQAKSDRRSQLIAAAERLVAERGYLAVRLEDIG
MAB_4541|M.abscessus_ATCC_1997 ---MTNLIPESETPNKRERAKADRRDQLLRAAARLLAMRGYARVRLEDLG
TH_2795|M.thermoresistible__bu DLPTPRRRRAPDPPPPRVTLAAGIYECVLHESIQMFHERGFRDTGMDDIA
MLBr_01733|M.leprae_Br4923 YPSMKPGVKIDARSERWREHRKKVRGEIVDAAFRALDRLG-PEVSVREIA
:: : : . * . : ::.
Mb2534|M.bovis_AF2122/97 AAAGVSGPAIYRHFPNKESLLVELLVGVSARLLAGARDVTT-RSANLAAA
Rv2506|M.tuberculosis_H37Rv AAAGVSGPAIYRHFPNKESLLVELLVGVSARLLAGARDVTT-RSANLAAA
MAV_1669|M.avium_104 ASAGVSGPAIYRHFPNKESLLVELLVGISTRLLAGARQVRA-RSADAAAA
MMAR_3853|M.marinum_M AAAGISGPAIYRHFPNKESLLVELLVGISSRLLAGARQVTT-NSNDAAAA
MUL_3785|M.ulcerans_Agy99 AAAGISGPAIYRHFPNKESLLVELLVGISSRLLAGARQVTT-NSNDAAAA
Mvan_4092|M.vanbaalenii_PYR-1 AAAGISGPAIYRHFPNKEALLVELLVGISTRLLAGAVEVVDRAGDDADSA
Mflv_2551|M.gilvum_PYR-GCK SAAGISGPAVYRHFPNKEALLVELLVGISTRLLAGATDVVG-ADDDAAST
MSMEG_4718|M.smegmatis_MC2_155 AAVGVSGPAIYRHFPNKEAMLVELLVGISTRLLDGAREVVE-THDDPAKA
MAB_4541|M.abscessus_ATCC_1997 SAVGISGPAIYRHFPNKEALLVDLLTDVSRRLLEGGMTVAA-AASSPAEA
TH_2795|M.thermoresistible__bu AAVGVPTTGIYRYFPGKADILAASLRRAVDRTSQDLARITA-ATADPHTA
MLBr_01733|M.leprae_Br4923 EEAGTAKPKIYRHFTDKSDLFEAIGIRLRDMLWAAIFPAIDLATDSAREI
.* . . :**:*..* :: .
Mb2534|M.bovis_AF2122/97 LDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQRQYVEVWVG
Rv2506|M.tuberculosis_H37Rv LDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQRQYVEVWVG
MAV_1669|M.avium_104 LDGLIDFHLDFALNEPDLIRIQDRDLAYLPKPAERQVRKAQRQYVEVWVG
MMAR_3853|M.marinum_M LDGLIDFHLDFALGEPDLIRIQDRDLGHLPAAAERQVRKAQRQYVEIWVG
MUL_3785|M.ulcerans_Agy99 LDGLIDFHLDFALGEPDLIRIQDRDLGHLPAAAERQVRKAQRQYVEIWVG
Mvan_4092|M.vanbaalenii_PYR-1 LEGLIDFHLDFVFGEPDLIRIQDRDLGNLPPAAKRQVRRKQRQYVEIWVD
Mflv_2551|M.gilvum_PYR-GCK LENLIDFHLDFALDESDLIRIQDRDLGNLPPAAKRQVRRKQRQYVEIWVD
MSMEG_4718|M.smegmatis_MC2_155 LDALVDFHLDFAFDESDLIRIQDRDLAHLPDTAKRQVRRAQRQYVEIWVS
MAB_4541|M.abscessus_ATCC_1997 LDGLIDFHLDFALNESDLIRVQDRDLDSLPENARRQVRQYQRRYVEAWVQ
TH_2795|M.thermoresistible__bu LTQLVRAYLDQFRERPALAYVQHTERRNLPESEARVVERIEQSLVDSWAR
MLBr_01733|M.leprae_Br4923 IRRSVDEYVSLVDKHPNVLRVFIQGRFSAQSEATVRTLDEGREITLTMAE
: : ::. .. : : . : . .
Mb2534|M.bovis_AF2122/97 VLR--ELNPGLAEADARLMAHAVFGLLNSTPHSMKAADS---KPARTVRA
Rv2506|M.tuberculosis_H37Rv VLR--ELNPGLAEADARLMAHAVFGLLNSTPHSMKAADS---KPARTVRA
MAV_1669|M.avium_104 VLR--ELNPELAEADARLTAHAVFGLLNSTPHSMKSQDSGRGKPARAARS
MMAR_3853|M.marinum_M VLR--QLDPGLAEADARLMAHAAFGLLNSTPHSMKSADT---KSACAPHS
MUL_3785|M.ulcerans_Agy99 VLR--QLDPGLAEADARLMAHAAFGLLNSTPHSMESADT---KSACAPHS
Mvan_4092|M.vanbaalenii_PYR-1 VLR--RRTPGLTETDARLMAHAAFGLLNSTPHGVKPGLN--KA--AEASS
Mflv_2551|M.gilvum_PYR-GCK VLR--RCTPGLSEADARLMAHGTFGLLNSTAHSMKPGTT--KT--AEAGS
MSMEG_4718|M.smegmatis_MC2_155 VLT--RLRRDLPEEEARVMAHATFGLLNSTPHSVKPAVT--KAQSSTAQS
MAB_4541|M.abscessus_ATCC_1997 VLC--RSQQGLDESDARIKAHAAFGLMNSTPYSAGRSAP--------SQT
TH_2795|M.thermoresistible__bu LVT--EQRPELTVATARYAVYCAFALVTDLGRLTDSHAS-------PSAQ
MLBr_01733|M.leprae_Br4923 MFNNELREMELNRAASELAAFAAFGSVASATEWWLGPEPDSPRRMPREQF
:. * :. .. .*. : .
Mb2534|M.bovis_AF2122/97 RAVLRAMTVAALSAADRCL---------------------
Rv2506|M.tuberculosis_H37Rv RAVLRAMTVAALSAADRCL---------------------
MAV_1669|M.avium_104 RAIMRAMTVAALAAGNQCP---------------------
MMAR_3853|M.marinum_M RAVMRAMTVAALTVDVGA----------------------
MUL_3785|M.ulcerans_Agy99 RAVMRAMTVAALTVDVGA----------------------
Mvan_4092|M.vanbaalenii_PYR-1 RTVLRTMTVAALTSAGRRA---------------------
Mflv_2551|M.gilvum_PYR-GCK RTVLREMTVAALTSAERRRG--------------------
MSMEG_4718|M.smegmatis_MC2_155 RGVLRRMTVAALTATG------------------------
MAB_4541|M.abscessus_ATCC_1997 RTVLRQMVVAALRS--------------------------
TH_2795|M.thermoresistible__bu AAVQHLMEVVLLGG--------------------------
MLBr_01733|M.leprae_Br4923 VAHLTIIMMAVIVGTAETLGISMNPDRPIHDAVPLDRSAS
: :. :