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METVDPDDLTARARIRDAALREFGDKGYDGATIRGIAARAGVSSGLLRHHFGSKQELRDACDEYLVKTMR DINEQVQANVERGDVHYVSARIPVGQYQAYITRALVEGSAGQLFDEMVAMTEGWLAVADQNRAYPAAVDV KSRAAVITAMALAVPLLQQHVSRGLGVDIDSPEGDLKMAATLVDVYANPLLTPEQAKSAQEDLARRMR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1518 | - | - | 100% (208) | hypothetical protein MAB_1518 |
| M. abscessus ATCC 19977 | MAB_1360c | - | 7e-14 | 56.25% (64) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1861c | - | 2e-12 | 28.75% (160) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1251c | - | 4e-15 | 33.80% (142) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2198 | - | 1e-16 | 31.22% (189) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1219c | - | 4e-15 | 33.80% (142) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_4219 | - | 3e-19 | 38.12% (160) | transcriptional regulator |
| M. avium 104 | MAV_4046 | - | 8e-90 | 77.29% (207) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5074 | - | 2e-15 | 34.75% (141) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0547 | - | 2e-16 | 35.46% (141) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_1500 | - | 3e-17 | 34.17% (199) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4498 | - | 2e-16 | 32.46% (191) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1251c|M.bovis_AF2122/97 --MR-SADLTAHARIREAAIEQFGRHGFG-VGLRAIAEAAGVSAALVIHH
Rv1219c|M.tuberculosis_H37Rv --MR-SADLTAHARIREAAIEQFGRHGFG-VGLRAIAEAAGVSAALVIHH
MMAR_4219|M.marinum_M --MR-SVDLTAAARIRDAAIEQFGQHGFG-VSLRAIAEGAGVSAALVIHH
MSMEG_5074|M.smegmatis_MC2_155 -----MDDRTAMARIRDTAIEQFGQHGFN-VGLRSIAEAAGVSAALVIHH
TH_0547|M.thermoresistible__bu --MRSADDRTAAARIRDAAIDQFGRHGFD-VSVRAIAEAAGVSPALVIHH
Mflv_2198|M.gilvum_PYR-GCK --MRSVDDLTAAARIRDAAVELFGAEGFA-VSVRTIAAAAGVSPGLVIHH
Mvan_4498|M.vanbaalenii_PYR-1 --MRSADDLTAAARIRDAAIDLFGRDGFA-VGVRSIASAAGVSPGLVIHH
MAB_1518|M.abscessus_ATCC_1997 METVDPDDLTARARIRDAALREFGDKGYDGATIRGIAARAGVSSGLLRHH
MAV_4046|M.avium_104 MTTTDPDDLTARARIRHAALREFGEKGYEGATIRSIAAAAGVSSGLLRHH
MUL_1500|M.ulcerans_Agy99 -MHLATDDRTARARIRDEALRLFAERGPDAVTMRDIATAAGVSPALLIRH
* ** ****. *: *. * . :* ** ****..*: :*
Mb1251c|M.bovis_AF2122/97 FGSKEGLRKACDDFVAEEIRSSKAAALKSNDPTTWLAQMAEIESY-----
Rv1219c|M.tuberculosis_H37Rv FGSKEGLRKACDDFVAEEIRSSKAAALKSNDPTTWLAQMAEIESY-----
MMAR_4219|M.marinum_M FGSKEGLRKACDNYVAEEIRSEKLTAMQSNDPATWLGQLAQVESY-----
MSMEG_5074|M.smegmatis_MC2_155 FGSKEGLRKACDDHVAEVILELKTESMHASDPATWLAYVAEIESY-----
TH_0547|M.thermoresistible__bu FGSKDNLRKACDDHIAEEIRSGKSAAIRSNDPATWFAQIAELESY-----
Mflv_2198|M.gilvum_PYR-GCK FGSKDQLHKACDAYVAETVRAAKSESIQTSDPATWLAQMAEIEEY-----
Mvan_4498|M.vanbaalenii_PYR-1 FGSKDGLRKACDDFVAETVRASKSEAIQSSDPATWLAQIAEIEEY-----
MAB_1518|M.abscessus_ATCC_1997 FGSKQELRDACDEYLVKTMRDINEQVQANVERGDVHYVSARIPVG-----
MAV_4046|M.avium_104 FGSKQELRQACDDYLVKTMRDLNAQVQDNAKRGDVHYVSARIRLG-----
MUL_1500|M.ulcerans_Agy99 YGSKDGLIEAVDNHVIAIFEVLLTEATRETEAVGLGQAAVGGLLDGLATH
:***: * .* * .: . . .
Mb1251c|M.bovis_AF2122/97 ----APLMAYLVRSMQSGGELAKMLWQKMIDNAEEYLDEGVRAGTVKPSR
Rv1219c|M.tuberculosis_H37Rv ----APLMAYLVRSMQSGGELAKMLWQKMIDNAEEYLDEGVRAGTVKPSR
MMAR_4219|M.marinum_M ----APLMAYLVRSMQSGGELAMMLWQQMIDNAEEYLAVGVRAGTIKASR
MSMEG_5074|M.smegmatis_MC2_155 ----APLMAYLVRSMQSGSELAKKFWRRMVDNAEQYLEEGVRTGMLKPSR
TH_0547|M.thermoresistible__bu ----APIMAYLVRSMQSGSDLAKMLWQKMIDDTRWYLDEGERAGTVKPSR
Mflv_2198|M.gilvum_PYR-GCK ----APLMAYLVRSLQAGGELGKMLWRTMTNDVEQYLEDGVRAGTVKPSA
Mvan_4498|M.vanbaalenii_PYR-1 ----APLMAYLVRTLQTGGELAKMLWQNMIDNAEQYIEEGVRAGTVKPSA
MAB_1518|M.abscessus_ATCC_1997 -----QYQAYITRALVEGSAG--QLFDEMVAMTEGWLAVADQNRAYPAAV
MAV_4046|M.avium_104 -----QYQDYITRALVEGGAG--ELFDALVSMTEEWLASADEHRAEPADV
MUL_1500|M.ulcerans_Agy99 LPPDSAVPAYLSRMLISGGTAGPGLFARLFRLSQDTLNAMAAAGTASPGA
*: * : *. :: : . : .
Mb1251c|M.bovis_AF2122/97 DPRARARFLAITGGGGFLLYLQMHENPTDLRAALRDYAHDMVLPSLEVYT
Rv1219c|M.tuberculosis_H37Rv DPRARARFLAITGGGGFLLYLQMHENPTDLRAALRDYAHDMVLPSLEVYT
MMAR_4219|M.marinum_M DPKARAKFLAITGAGGFLLYLQMHQTPTDLRAVLRDYARDMLLPSLEIYT
MSMEG_5074|M.smegmatis_MC2_155 DPRARARFLAICGGGGFLLYLQMHDNPTDLRAVLRDYGEDMMLPALEIYS
TH_0547|M.thermoresistible__bu DPKARARFLAISGGGSFLLYLQLHDNPTDLAAVLRDYSRDMMLPALEIYT
Mflv_2198|M.gilvum_PYR-GCK DPRARAFFLSMASGGGFLLYLQLHES-TDIRVVLRDYSEAMVLPALELYT
Mvan_4498|M.vanbaalenii_PYR-1 DPRGRARFLAMAGGGGFLLYLQMHDNPTDLRAVLRDYSEEMVLPALELYT
MAB_1518|M.abscessus_ATCC_1997 DVKSRAAVITAMALAVPLLQQHVSRG-LGVDIDSPEGDLKMAATLVDVYA
MAV_4046|M.avium_104 DAKSRATLITAMALAIPLLRQHISRG-LGVDISTEQGDLRVAAILVDIYS
MUL_1500|M.ulcerans_Agy99 DPAVRAAFLLVNDLAVLTLRPRLIEV-LGVDPLTDAGMRRWAGEVFAVYR
* ** .: . * :: .: . :*
Mb1251c|M.bovis_AF2122/97 EGLLADRAMYEAFLAEAQQGEAHVG------------------
Rv1219c|M.tuberculosis_H37Rv EGLLADRAMYEAFLAEAQQGEAHVG------------------
MMAR_4219|M.marinum_M EGLMADSTMYDAFLAQDNQGESHGH------------------
MSMEG_5074|M.smegmatis_MC2_155 HGLMADTTMYETFLHQREAGVPFTGTSEEAT------------
TH_0547|M.thermoresistible__bu HGLMADSTMFDAFVARETQQLSDQGGAHDDDVAAV--------
Mflv_2198|M.gilvum_PYR-GCK HGLLTDSTMYDAFVAERAHDHSSPSTG-ARDA-----------
Mvan_4498|M.vanbaalenii_PYR-1 NGLMTDSTMYDAFVARRAQGIPFTSTEGAHDD-----------
MAB_1518|M.abscessus_ATCC_1997 NPLLTPEQAKSAQEDLARRMR----------------------
MAV_4046|M.avium_104 NPLLTPEQAKSARDDLAGRLSAAAGPPGRPGRAAAAGRRPAPR
MUL_1500|M.ulcerans_Agy99 DGLVSD-------------------------------------
. *::