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MSFAVLPPEINSLRIFAGAGSAPMLEAAVAWDGLSAELGTAAESFASVTSGLTGQAWQGAAAKAMAAVAA PYSSWLSAAAARAAGAAGQAKMVASAFEAARSAMVHPLAVAANRNVFVQLVMSNLFGQNAPAIAATEGTY EEMWAADVAAMVGYHGGASAAASGLPSWQQALSGLPGIGQAAAAPAAALFNLPTVNTGLGNSGQWNLGGG NNGSFNLGSGNFGNLNLGGGNIGNLNLGGGNFGFANLGNGNIGNTNFGSGNNGNLNFGGGNLGSGNFGLG NFGSGNFGNANGMDPVSFSTGNNIGDANLGAFNLGSANIGLSNIGLANIGNNNFGFGNVGNNNIGFGLTG DNQVGIGSLNAGTGNFGFGNSGDNNIGFFNSGSGNVGVFNSGDGNTGFGNSGGVNSGFWNSGGLNTGFGN AGANNLGFSNAGSSNVGDSNAGGSNMGSGNAGYSNTGFFNSGGSATFIGGNTGFFNSGDLNTGGGNAGSV NTGFLNSGDFNTTVGSADTPAGATQSGFWNTGDNVSGFNNTNDAMFGGGVSGFQNMNTGFFSVGSGFGNT GEYQVGFNNAGTGFNTGVGNTGSFNTGFNVTGSGSSGFGHSGDGSSGLANSGDSSSGAFNETDNTAGFFG QS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1402 | - | - | 100% (632) | PPE family protein |
| M. marinum M | MMAR_1139 | - | 0.0 | 63.05% (636) | PPE family protein |
| M. marinum M | MMAR_4319 | - | 0.0 | 60.84% (641) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3184c | PPE70 | 0.0 | 68.42% (646) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-28 | 25.53% (658) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3159c | PPE53 | 0.0 | 59.65% (637) | PPE family protein |
| M. leprae Br4923 | MLBr_01182 | - | 2e-29 | 40.22% (179) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_0669 | - | 7e-23 | 34.86% (175) | PPE-family protein |
| M. avium 104 | MAV_4704 | - | 1e-48 | 53.85% (182) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 8e-30 | 29.94% (531) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3113 | - | 8e-25 | 38.46% (182) | PUTATIVE PPE protein |
| M. ulcerans Agy99 | MUL_0902 | - | 0.0 | 62.58% (636) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 5e-31 | 25.51% (682) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1402|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1402|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1402|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1402|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 -----------------------------------MN---YSVLPPEINS
Rv3159c|M.tuberculosis_H37Rv -----------------------------------MN---YSVLPPEINS
MUL_0902|M.ulcerans_Agy99 -----------------------------------MN---FPMLPPEINS
MMAR_1402|M.marinum_M -----------------------------------MS---FAVLPPEINS
MAV_4704|M.avium_104 -----------------------------------MTNPHFAWLPPEVNS
MAB_0669|M.abscessus_ATCC_1997 -----------------------------------MTAPIWMAEPPEVHS
TH_3113|M.thermoresistible__bu -----------------------------------------MALPPEVHS
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MLBr_01182|M.leprae_Br4923 -------------------------------------MFDFAALSPETNS
: .
Mb3184c|M.bovis_AF2122/97 LRMFTGAGSAPMLAASVAWDGLAAELAVAASSFGSVTSGLAGQSWQG-AA
Rv3159c|M.tuberculosis_H37Rv LRMFTGAGSAPMLAASVAWDRLAAELAVAASSFGSVTSGLAGQSWQGAAA
MUL_0902|M.ulcerans_Agy99 ARMFAGAGSGPMLSAAMAWDGLAVELGSAAESFGSVTSGLVGSSWQGAAA
MMAR_1402|M.marinum_M LRIFAGAGSAPMLEAAVAWDGLSAELGTAAESFASVTSGLTGQAWQGAAA
MAV_4704|M.avium_104 ALIYSGPGPGPLLAAAAAWDGLAEELASSAQSFSSVTSDLASGSWQGASS
MAB_0669|M.abscessus_ATCC_1997 ALLSAGPGPGAVLAAAVQWQEIGNNYANTAVELAQVLAGVRAGSWQGPSA
TH_3113|M.thermoresistible__bu TLLRTGPGPGALSAAADAWRMLSDEYRAAAVELAAVVSQTCATAWEGVGA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MLBr_01182|M.leprae_Br4923 TRMYLGPGSSPILTAAAAWVVLAKELTAAAQGLQSAVEALLTT-FEGESA
* . .. : * ..
Mb3184c|M.bovis_AF2122/97 AAMAAAAAPYAGWLAAAAARAAGASAQAKAVASAFEAARAATVHPMLVAA
Rv3159c|M.tuberculosis_H37Rv AAMAAAAAPYAGWLAAAAARAAGASAQAKAVASAFEAARAATVHPMLVAA
MUL_0902|M.ulcerans_Agy99 TAMSAAAAPYVSWLNAAAVRAGEAALQAKEVVSAFEAARAAMIHPLAVAA
MMAR_1402|M.marinum_M KAMAAVAAPYSSWLSAAAARAAGAAGQAKMVASAFEAARSAMVHPLAVAA
MAV_4704|M.avium_104 AAMMTVANQYVSWLSAAAAQAEEVSHQASAIATAFEVALAATVQPAVVAA
MAB_0669|M.abscessus_ATCC_1997 SEYVAAHLPYLAWLEQAAAESSVIAAQHETTAAAYNSALAAMPTLAELAA
TH_3113|M.thermoresistible__bu DAYAAAHGPYLFWLTDTAAAAAAAGAQLEAAAAAHASALAAMPTMAELTA
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
MLBr_01182|M.leprae_Br4923 AALAERVTPYEKWLTQNAASAELTATQLTVAANAYETAFTMTVPPLMVFV
* . . .
Mb3184c|M.bovis_AF2122/97 NRNAFVQLVLSNLFGQNAPAIAAAEAMYEQ--------------------
Rv3159c|M.tuberculosis_H37Rv NRNAFVQLVLSNLFGQNAPAIAAAEAMYEQ--------------------
MUL_0902|M.ulcerans_Agy99 NRNALVQLVLTNLFGQNAPAIAAAEGSYEQ--------------------
MMAR_1402|M.marinum_M NRNVFVQLVMSNLFGQNAPAIAATEGTYEE--------------------
MAV_4704|M.avium_104 NRALVQALAATNWLGQNTPAIADIEAAYEQ--------------------
MAB_0669|M.abscessus_ATCC_1997 NHITHGVLVGTNFFGINTIPIALNEADYVR--------------------
TH_3113|M.thermoresistible__bu NRTTHAALVATNFFGVNTIPIAVNEADYAR--------------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
MLBr_01182|M.leprae_Br4923 NRAQACLLIMSNIFGQNSTAIAEKEAEYTE--------------------
. : .
Mb3184c|M.bovis_AF2122/97 MWAADVAAMVGYHGGASAAAAALPSWQQALRGLPGLGQVASAIS------
Rv3159c|M.tuberculosis_H37Rv MWAADVAAMVGYHGGASAAAAQLSSWSIGLQ-------------------
MUL_0902|M.ulcerans_Agy99 MWAADVAAMLGYHGGASAAASGLASWQQALQG------------------
MMAR_1402|M.marinum_M MWAADVAAMVGYHGGASAAASGLPSWQQALSG------------------
MAV_4704|M.avium_104 MWASDVAAMFGYHADASAAVAKLPPWNEVLQ-------------------
MAB_0669|M.abscessus_ATCC_1997 MWVQAAATMSAYQATTEAMTSAIPPTQQPPA-------------------
TH_3113|M.thermoresistible__bu MWIQAATTMATYEAVASAAVSATPRTVAPPP-------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
MLBr_01182|M.leprae_Br4923 MWIQDAAAMTSYQASVLEAVGATKAFTAPPLG------------------
: . .
Mb3184c|M.bovis_AF2122/97 ------GGAASMFAAPAAATAAVTPPAL-NTGLGNIGSWNLGGGNVGLLN
Rv3159c|M.tuberculosis_H37Rv ---------QALPAAPSALAAAIG--------LGNIGVGNLGGGNTGDYN
MUL_0902|M.ulcerans_Agy99 ---------LAGPAASVILGLSIGNTGVGNLSIGNIGVFNLGGGNAGNLN
MMAR_1402|M.marinum_M --------LPGIGQAAAAPAAALFNLPTVNTGLGNSGQWNLGGGNNGSFN
MAV_4704|M.avium_104 -------------------------------------------------N
MAB_0669|M.abscessus_ATCC_1997 -----------------------------------------------ILS
TH_3113|M.thermoresistible__bu -----------------------------------------------ILG
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
MLBr_01182|M.leprae_Br4923 -----------------------------------------------VNE
Mb3184c|M.bovis_AF2122/97 LGSGNFGSLNLG--------------------------------------
Rv3159c|M.tuberculosis_H37Rv LGSGNSGNANVG--------------------------------------
MUL_0902|M.ulcerans_Agy99 LGGGNTGNANLG--------------------------------------
MMAR_1402|M.marinum_M LGSGNFGNLNLG--------------------------------------
MAV_4704|M.avium_104 LGFSNASTAVTR--------------------------------------
MAB_0669|M.abscessus_ATCC_1997 PGG-----------------------------------------------
TH_3113|M.thermoresistible__bu AGTGESATAAITG-------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
MLBr_01182|M.leprae_Br4923 VGLAQEVVEEVV--------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1402|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 ----GGNTGNANLGGGNWGFANLGS-------------------GNIGNT
Rv3159c|M.tuberculosis_H37Rv ----SGNSGNANVGSGNDGATNLGS-------------------GNIGNT
MUL_0902|M.ulcerans_Agy99 ----SGNNGFFNLGSGNTGNTNFGN-------------------GNRGNL
MMAR_1402|M.marinum_M ----GGNIGNLNLGGGNFGFANLGN-------------------GNIGNT
MAV_4704|M.avium_104 ----PAGSGAVARG------------------------------------
MAB_0669|M.abscessus_ATCC_1997 ----EARSDQS---------------------------------------
TH_3113|M.thermoresistible__bu -AHVTAELRAA---------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 NFGNGNQGNLNFGS------------------------------------
Rv3159c|M.tuberculosis_H37Rv NLGSGNVGNVNLGS------------------------------------
MUL_0902|M.ulcerans_Agy99 NWGSGNLGNANVGF------------------------------------
MMAR_1402|M.marinum_M NFGSGNNGNLNFGG------------------------------------
MAV_4704|M.avium_104 -YTSRIAGFLAPRA------------------------------------
MAB_0669|M.abscessus_ATCC_1997 DVPGSPDQIMKMLQ------------------------------------
TH_3113|M.thermoresistible__bu ESRTLLDEINELID------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
MLBr_01182|M.leprae_Br4923 --EEVVEEVVEAEQ------------------------------------
Mb3184c|M.bovis_AF2122/97 -----------GNLLGNGNFGFGNAFGDGNLGSGN---------------
Rv3159c|M.tuberculosis_H37Rv -----------GNR-GFGNLGNGN-FGSGNLGSGN---------------
MUL_0902|M.ulcerans_Agy99 -----------GNFLGQGNFGFGNRVGDANLGSGN---------------
MMAR_1402|M.marinum_M -----------GNL-GSGNFGLGN-FGSGNFGNANGMD------------
MAV_4704|M.avium_104 -----------PQ-------------------------------------
MAB_0669|M.abscessus_ATCC_1997 -----------GFQQWFEKMGFNPAT------------------------
TH_3113|M.thermoresistible__bu -----------RLFAPLFPPGFADALPDGLLGTLL---------------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 ----VGSTNLGSGNFGSFNVGSGNMGMSNIGFGNLGNNNLGFGNNGNNNI
Rv3159c|M.tuberculosis_H37Rv ----TGSTNFGGGNLGSFNLGSGNIGSSNIGFGNNGDNNLGLGNNGNNNI
MUL_0902|M.ulcerans_Agy99 ----LGNANFGNGNLGDTNLGSGNNGFSNVGFGNLGSNNLGFGNNGDNNI
MMAR_1402|M.marinum_M PVSFSTGNNIGDANLGAFNLGSANIGLSNIGLANIGNNNFGFGNVGNNNI
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 ------------SAVLAVIMLFLYDLLWYPYYAS----------------
TH_3113|M.thermoresistible__bu --APLLPGATGDGPPMATIMSFLLMGLSNPAYLFPVLVYLLFTGVVHTTV
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
MLBr_01182|M.leprae_Br4923 ------------AISQAALDQAVNEGMEAT--------------------
Mb3184c|M.bovis_AF2122/97 GFGLTGDNLVGIG--ALNSGIGNMGF------------------------
Rv3159c|M.tuberculosis_H37Rv GFGLTGDNLVGIG--ALNSGIGNLGF------------------------
MUL_0902|M.ulcerans_Agy99 GFGLTGNNQVGINFAGLNGGIGNIDL------------------------
MMAR_1402|M.marinum_M GFGLTGDNQVGIG--SLNAGTGNFGF------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 --------------YLLPFLIPALS-------------------------
TH_3113|M.thermoresistible__bu AVSGMLAQLVPLMPALLPVAVAALG-------------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1402|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
Mvan_1264|M.vanbaalenii_PYR-1 AG-----------DGLGGTGGTGG----TGGFGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1402|M.marinum_M --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ
Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGQGG-LGGVGGTG-----------------------GT
MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 ------------------------------GNSGNNNIGFFNSGNGNVGF
Rv3159c|M.tuberculosis_H37Rv ------------------------------GNSGNNNIGFFNSGNNNVGF
MUL_0902|M.ulcerans_Agy99 ------------------------------GNSGDNNVGFFNSGSNNVGF
MMAR_1402|M.marinum_M ------------------------------GNSGDNNIGFFNSGSGNVGV
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 --------------------------------------GLS----GLAAL
TH_3113|M.thermoresistible__bu --------------------------------------GLAGVWAGLSGL
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 FNSGDGNTGFGNAGDVNTGFWNGGPFNTGFGNGGNTNFGFGNAGFQNMGH
Rv3159c|M.tuberculosis_H37Rv FNSGNNNFGFGNAGDINTGFGNAGDTNTGFGNAGFFNMGIGNAGNEDMGV
MUL_0902|M.ulcerans_Agy99 FNSGDRNFGFANSGDTNTGFWNAGRVNTGFGNGGNFNLGFGNGGAANVGV
MMAR_1402|M.marinum_M FNSGDGNTGFGNSGGVNSGFWNSGGLNTGFGNAGANNLGFSNAGSSNVGD
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 MHLR-----PAAPGPVPAAALSPGDRPIRRPTQHVEPNLAALPLPTSSVV
TH_3113|M.thermoresistible__bu AGLAGLTAVPAADGGASAAPVPAGG-PSLPSGSSAPPAPTGSAAPTTGTA
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA
MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL
MLBr_01182|M.leprae_Br4923 ----------VVPQVDQQVNVDVATPQTAVPDSSSAAAPQLWGGFAQHLS
Mb3184c|M.bovis_AF2122/97 GNAGGVNVGSGNAGLANTGDFNSGG------VVSGIGGNTGSFNSGNLNT
Rv3159c|M.tuberculosis_H37Rv GNGGSFNVGVGNAGNQSVG-FGNAG------TLN-----VGFANAGSINT
MUL_0902|M.ulcerans_Agy99 GNGGGGNLGFGNSGTENTGSFNSGG------DNGRNGGNTGSFNSGYVNT
MMAR_1402|M.marinum_M SNAGGSNMGSGNAGYSNTGFFNSGG------SATFIGGNTGFFNSGDLNT
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 PSGGSSVPVSTPTAPAHTVSSVPAP------SAAISYAIPGLVPPGVSFG
TH_3113|M.thermoresistible__bu PGGAGSPPPAGHSVPPAPHSAPPVG------TSGPPYLIAAQPAPGVARR
Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1 GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
MLBr_01182|M.leprae_Br4923 PINDTLSMINNHAGMANAGLSLVNG-------MGSAMKSLAPTTTKAAES
Mb3184c|M.bovis_AF2122/97 GFGNAGDLNTGL----------------FNSGDVNTGIGSTVDQP-GSVS
Rv3159c|M.tuberculosis_H37Rv GFANSGSINTGG----------------FDSGDRNTGFGSSVDQS-VSSS
MUL_0902|M.ulcerans_Agy99 GFFNSGSTNTGL----------------FNAGSVNTGIGSPDTQP-GSIS
MMAR_1402|M.marinum_M GGGNAGSVNTGF----------------LNSGDFNTTVGSADTPAGATQS
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 PKSTEKSSESAV----------------DTVAAVAAARGAVAAQARRRLR
TH_3113|M.thermoresistible__bu SAGARR-AASIV----------------EPAGSAAAAAAARESAPIRRRR
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
MLBr_01182|M.leprae_Br4923 AFKAMGSAVQST-----------------GRGLLGSSSGGHVTAQLGRAA
Mb3184c|M.bovis_AF2122/97 GFGNTGTSVSGFNNS-----GNLTSGFGNMNSNVFDSTSGFQNIGDANVG
Rv3159c|M.tuberculosis_H37Rv GFGNTGMNSSGFFNT-----GNVSAGYGNNG----DVQSGINNT------
MUL_0902|M.ulcerans_Agy99 GFGNTGAGVSGFNNS-----GDATSGFMNVATT-FGFASGINNV------
MMAR_1402|M.marinum_M GFWNTGDNVSGFNNTNDAMFGGGVSGFQNMNTGFFSVGSGFGNTGEYQVG
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 GKNKAEAG------------GRRHEYLEETAGMGATATADVPAY------
TH_3113|M.thermoresistible__bu GQ-KDGLH------------GHRHEHQQPASMSAATAPSAAGIR------
Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
MLBr_01182|M.leprae_Br4923 SIGSLRVP----------------QTWTTASQPVTAATRALSPAR-----
Mb3184c|M.bovis_AF2122/97 FFNS-GNSNEGFFNTGMFNNGIYNS------GVASTGIANSGNASSGVAN
Rv3159c|M.tuberculosis_H37Rv --NS-GGFNVGFYNSGAGTVGIANS------GLQTTGIANSGTLNTGVAN
MUL_0902|M.ulcerans_Agy99 -----GDYQVGLFNTGFGNAGIANS------GNATFGIANSGALSSGISN
MMAR_1402|M.marinum_M FNNAGTGFNTGVGNTGSFNTGFNVT------GSGSSGFGHSGDGSSGLAN
MAV_4704|M.avium_104 --------------------------------------------------
MAB_0669|M.abscessus_ATCC_1997 ----------AATGRGTGPLGFAGT------APAAASTHVAATVRLSSDE
TH_3113|M.thermoresistible__bu ----------VLG--GAGRISRTRG------SVPHAEITPGDPTEPSSPT
Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN
MLBr_01182|M.leprae_Br4923 ---------VAVATESESAPLLGGG------LPMAPMVPGGGSGTGGVNT
Mb3184c|M.bovis_AF2122/97 SGDNSSGAFNQGDNQAGFFGQP-----
Rv3159c|M.tuberculosis_H37Rv TGDHSSGGFNQGSDQSGFFGQP-----
MUL_0902|M.ulcerans_Agy99 SGTNSSGGFNTGDDQSGFFN-------
MMAR_1402|M.marinum_M SGDSSSGAFNETDNTAGFFGQS-----
MAV_4704|M.avium_104 ---------------------------
MAB_0669|M.abscessus_ATCC_1997 ARQVIPMLPSTWDADGGDQN-------
TH_3113|M.thermoresistible__bu DRAHRPAEPN-----------------
Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGGADGTPGTAGTTGANNP
MLBr_01182|M.leprae_Br4923 ALRLQPRAFVMPRNPAAG---------