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MNFPMLPPEINSARMFAGAGSGPMLSAAMAWDGLAVELGSAAESFGSVTSGLVGSSWQGAAAAAMSAAAA PYVSWLNAAAVRAGEAALQAKEVVSAFEAARAAMIHPLAVAANRNALVQLVLTNLFGQNAPAIAAAEGSY EQMWAADVAAMLGYHGGASAAASGLASWQQALQGLAGPAASVIPGLSIGNIGVGNLSIGNIGDFNLGGGN AGNLNLGGGNTGNANLGSGNNGFFNLGSGNTGNTNFGNGNRGNLNWGSGNLGNANVGFGNFLGQGNFGFG NRVGDANLGSGNLGNANFGNGNLGDTNLGSGNNGFSNVGFGNLGSNNLGFGNNGDNNIGFGLTGNNQVGI NFAGLNGGIGNIGLGNSGDNNVGFFNSGSNNVGFFNSGDGNFGFANAGDTNTGFWNAGRVNTGFGNGGNF NLGFGNGGAANVGVGNGGGGNMGFGNSGTENTGSFNSGGDNGPNGGNTGSFNSGYVNTGFFNSGSTNTGL FNAGSVNTGIGSPDTQPGSISGFGNTGAGVSGFNNSGDATSGFMNVATTFGFTSGINNVGDYQVGLFNTG FGNAGIANSGNATFGIANSGALSSGISNSGTNSSGGFNTGDDQSGFFN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1139 | - | - | 100% (608) | PPE family protein |
| M. marinum M | MMAR_4319 | - | 0.0 | 65.02% (629) | PPE family protein |
| M. marinum M | MMAR_1402 | - | 0.0 | 63.05% (636) | PPE family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3184c | PPE70 | 0.0 | 67.29% (642) | PPE family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 4e-28 | 29.22% (486) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3159c | PPE53 | 0.0 | 64.43% (610) | PPE family protein |
| M. leprae Br4923 | MLBr_01182 | - | 7e-28 | 35.42% (192) | PPE-family protein |
| M. abscessus ATCC 19977 | MAB_4284c | - | 3e-24 | 27.80% (518) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4704 | - | 1e-51 | 56.11% (180) | PPE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 7e-25 | 27.96% (515) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3113 | - | 5e-23 | 37.97% (158) | PUTATIVE PPE protein |
| M. ulcerans Agy99 | MUL_0902 | - | 0.0 | 98.36% (608) | PPE family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 2e-29 | 28.97% (611) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1139|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1139|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1139|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MMAR_1139|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
MMAR_1139|M.marinum_M -----------------------------------MN---FPMLPPEINS
MUL_0902|M.ulcerans_Agy99 -----------------------------------MN---FPMLPPEINS
Mb3184c|M.bovis_AF2122/97 -----------------------------------MN---YSVLPPEINS
Rv3159c|M.tuberculosis_H37Rv -----------------------------------MN---YSVLPPEINS
MAV_4704|M.avium_104 -----------------------------------MTNPHFAWLPPEVNS
MLBr_01182|M.leprae_Br4923 -------------------------------------MFDFAALSPETNS
TH_3113|M.thermoresistible__bu -----------------------------------------MALPPEVHS
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MAB_4284c|M.abscessus_ATCC_199 EAALAN----------------AGLSAVSAAQVGAVMPVVAESVASNYGY
:
MMAR_1139|M.marinum_M ARMFAGAGSGPMLSAAMAWDGLAVELGSAAESFGSVTSGLVGSSWQGAAA
MUL_0902|M.ulcerans_Agy99 ARMFAGAGSGPMLSAAMAWDGLAVELGSAAESFGSVTSGLVGSSWQGAAA
Mb3184c|M.bovis_AF2122/97 LRMFTGAGSAPMLAASVAWDGLAAELAVAASSFGSVTSGLAGQSWQG-AA
Rv3159c|M.tuberculosis_H37Rv LRMFTGAGSAPMLAASVAWDRLAAELAVAASSFGSVTSGLAGQSWQGAAA
MAV_4704|M.avium_104 ALIYSGPGPGPLLAAAAAWDGLAEELASSAQSFSSVTSDLASGSWQGASS
MLBr_01182|M.leprae_Br4923 TRMYLGPGSSPILTAAAAWVVLAKELTAAAQGLQSAV-EALLTTFEGESA
TH_3113|M.thermoresistible__bu TLLRTGPGPGALSAAADAWRMLSDEYRAAAVELAAVVSQTCATAWEGVGA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MAB_4284c|M.abscessus_ATCC_199 QSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDT
* .. .
MMAR_1139|M.marinum_M AAMSAAAAPYVSWLNAAAVRAGEAALQAKEVVSAFE--------AARAAM
MUL_0902|M.ulcerans_Agy99 TAMSAAAAPYVSWLNAAAVRAGEAALQAKEVVSAFE--------AARAAM
Mb3184c|M.bovis_AF2122/97 AAMAAAAAPYAGWLAAAAARAAGASAQAKAVASAFE--------AARAAT
Rv3159c|M.tuberculosis_H37Rv AAMAAAAAPYAGWLAAAAARAAGASAQAKAVASAFE--------AARAAT
MAV_4704|M.avium_104 AAMMTVANQYVSWLSAAAAQAEEVSHQASAIATAFE--------VALAAT
MLBr_01182|M.leprae_Br4923 AALAERVTPYEKWLTQNAASAELTATQLTVAANAYE--------TAFTMT
TH_3113|M.thermoresistible__bu DAYAAAHGPYLFWLTDTAAAAAAAGAQLEAAAAAHA--------SALAAM
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
MAB_4284c|M.abscessus_ATCC_199 DFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDG
: .
MMAR_1139|M.marinum_M IHPLAVAANRNALVQLVLTNLFGQNAPAIAAAEGS---------------
MUL_0902|M.ulcerans_Agy99 IHPLAVAANRNALVQLVLTNLFGQNAPAIAAAEGS---------------
Mb3184c|M.bovis_AF2122/97 VHPMLVAANRNAFVQLVLSNLFGQNAPAIAAAEAM---------------
Rv3159c|M.tuberculosis_H37Rv VHPMLVAANRNAFVQLVLSNLFGQNAPAIAAAEAM---------------
MAV_4704|M.avium_104 VQPAVVAANRALVQALAATNWLGQNTPAIADIEAA---------------
MLBr_01182|M.leprae_Br4923 VPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKEAE---------------
TH_3113|M.thermoresistible__bu PTMAELTANRTTHAALVATNFFGVNTIPIAVNEAD---------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
MAB_4284c|M.abscessus_ATCC_199 AVAVGGSNSGPIASGQGSTAVNGDVRDSNIINADHG----------SNVG
. : * .
MMAR_1139|M.marinum_M YEQMWAADVAAMLGYHGGASAAASGLASWQQALQGLAG----------PA
MUL_0902|M.ulcerans_Agy99 YEQMWAADVAAMLGYHGGASAAASGLASWQQALQGLAG----------PA
Mb3184c|M.bovis_AF2122/97 YEQMWAADVAAMVGYHGGASAAAAALPSWQQALRGLPGLGQVASAISGGA
Rv3159c|M.tuberculosis_H37Rv YEQMWAADVAAMVGYHGGASAAAAQLSSWSIGLQ----------------
MAV_4704|M.avium_104 YEQMWASDVAAMFGYHADASAAVAKLPPWNEVLQ----------------
MLBr_01182|M.leprae_Br4923 YTEMWIQDAAAMTSYQASVLEAVGATKAFTAPP-----------------
TH_3113|M.thermoresistible__bu YARMWIQAATTMATYEAVASAAVSATPRTVAPPP----------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
MAB_4284c|M.abscessus_ATCC_199 VDQSQTRVGGDYTNVSGHGSADIDKSVTVVDDHS----------------
.
MMAR_1139|M.marinum_M ASVIPGLSIGNIGVG----NLSIGNIGDFNLGGGNAGNLNLGGGNTGNAN
MUL_0902|M.ulcerans_Agy99 ASVILGLSIGNTGVG----NLSIGNIGVFNLGGGNAGNLNLGGGNTGNAN
Mb3184c|M.bovis_AF2122/97 ASMFAAPAAATAAVTPPALNTGLGNIGSWNLGGGNVGLLNLGSGNFGSLN
Rv3159c|M.tuberculosis_H37Rv QALPAAPSALAAAIG-------LGNIGVGNLGGGNTGDYNLGSGNSGNAN
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
MAB_4284c|M.abscessus_ATCC_199 --QRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHNQANIGTSTSAGGSAA
MMAR_1139|M.marinum_M LGSGNNGFFNLG--------------------------------------
MUL_0902|M.ulcerans_Agy99 LGSGNNGFFNLG--------------------------------------
Mb3184c|M.bovis_AF2122/97 LGGGNTGNANLG--------------------------------------
Rv3159c|M.tuberculosis_H37Rv VGSGNSGNANVG--------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --LGVN--------------------------------------------
TH_3113|M.thermoresistible__bu -ILGAGTGESAT--------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
MAB_4284c|M.abscessus_ATCC_199 VGGNAGLAGNAG--------------------------------------
MMAR_1139|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1139|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1139|M.marinum_M --------------------------------------------------
MUL_0902|M.ulcerans_Agy99 --------------------------------------------------
Mb3184c|M.bovis_AF2122/97 --------------------------------------------------
Rv3159c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1139|M.marinum_M --------------SGNTGNTNFGNGNRGNLNWGS---------------
MUL_0902|M.ulcerans_Agy99 --------------SGNTGNTNFGNGNRGNLNWGS---------------
Mb3184c|M.bovis_AF2122/97 --------------GGNWGFANLGSGNIGNTNFGN---------------
Rv3159c|M.tuberculosis_H37Rv --------------SGNDGATNLGSGNIGNTNLGS---------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 ----------------------EVGLAQEVVEEVV---------------
TH_3113|M.thermoresistible__bu --------------AAITGAHVTAELRAAESRTLL---------------
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
MAB_4284c|M.abscessus_ATCC_199 -------------LAGNAGLAGNAGLAGNAGLAGN---------------
MMAR_1139|M.marinum_M ---GNLGNANVGFGNFLGQGNFGFGNRVGDANLGSGNLGNANFGNGNLGD
MUL_0902|M.ulcerans_Agy99 ---GNLGNANVGFGNFLGQGNFGFGNRVGDANLGSGNLGNANFGNGNLGD
Mb3184c|M.bovis_AF2122/97 ---GNQGNLNFGSGNLLGNGNFGFGNAFGDGNLGSGNVGSTNLGSGNFGS
Rv3159c|M.tuberculosis_H37Rv ---GNVGNVNLGSGNR-GFGNLGNGN-FGSGNLGSGNTGSTNFGGGNLGS
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 ---EEVVEEVVEAEQAISQAALDQAVNEGMEATVVPQVDQQVN-------
TH_3113|M.thermoresistible__bu ---DEINELIDRLFAPLFPPGFADALPDGLLGTLLAPLLPGATGDGPPMA
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
MAB_4284c|M.abscessus_ATCC_199 ---AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG
MMAR_1139|M.marinum_M TNLGSGNNGFSNVGFGNLGSNNLGFGNNGDNN------------------
MUL_0902|M.ulcerans_Agy99 TNLGSGNNGFSNVGFGNLGSNNLGFGNNGDNN------------------
Mb3184c|M.bovis_AF2122/97 FNVGSGNMGMSNIGFGNLGNNNLGFGNNGNNN------------------
Rv3159c|M.tuberculosis_H37Rv FNLGSGNIGSSNIGFGNNGDNNLGLGNNGNNN------------------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 -------------------------VDVATPQ------------------
TH_3113|M.thermoresistible__bu TIMSFLLMGLSNPAYLFPVLVYLLFTGVVHTT------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAG-----NAGLAGNAGLAGNAG------------------
MMAR_1139|M.marinum_M -------------IGFGLTGNNQVGINFAGLNGGIGNIGL----------
MUL_0902|M.ulcerans_Agy99 -------------IGFGLTGNNQVGINFAGLNGGIGNIDL----------
Mb3184c|M.bovis_AF2122/97 -------------IGFGLTGDNLVGIG--ALNSGIGNMGF----------
Rv3159c|M.tuberculosis_H37Rv -------------IGFGLTGDNLVGIG--ALNSGIGNLGF----------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 -------------TAVPDSSSAAAPQLWGGFAQHLSPIN-----------
TH_3113|M.thermoresistible__bu -------------VAVSGMLAQLVPLMPALLPVAVAALGG----------
Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
Mvan_1264|M.vanbaalenii_PYR-1 AG-----------DGLGGTGGTGG----TGGFGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
MAB_4284c|M.abscessus_ATCC_199 ------------LAGNAGLAGNAGLAGNAGLAGNAAVAGN----------
MMAR_1139|M.marinum_M ------------------------------------------------GN
MUL_0902|M.ulcerans_Agy99 ------------------------------------------------GN
Mb3184c|M.bovis_AF2122/97 ------------------------------------------------GN
Rv3159c|M.tuberculosis_H37Rv ------------------------------------------------GN
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------------------
TH_3113|M.thermoresistible__bu ------------------------------------------------LA
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ
Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGQGG-LGGVGGTG-----------------------GT
MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------------------AAV
MMAR_1139|M.marinum_M SGDNNVGFFNSGSNNVGFFNSGDGNFGFANAGDTNTGFWNAGRVNTGFGN
MUL_0902|M.ulcerans_Agy99 SGDNNVGFFNSGSNNVGFFNSGDRNFGFANSGDTNTGFWNAGRVNTGFGN
Mb3184c|M.bovis_AF2122/97 SGNNNIGFFNSGNGNVGFFNSGDGNTGFGNAGDVNTGFWNGGPFNTGFGN
Rv3159c|M.tuberculosis_H37Rv SGNNNIGFFNSGNNNVGFFNSGNNNFGFGNAGDINTGFGNAGDTNTGFGN
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 ---DTLSMINN------------------HAGMANAGLSLVNGMGSAMKS
TH_3113|M.thermoresistible__bu GVWAGLSGLAG------------------LAGLTAVPAADGGASAAPVPA
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
MAB_4284c|M.abscessus_ATCC_199 AGNAAVAGNAAVGGVLNTGVSGAIGGSSHVGGAINESLGGSGSVGGSTAV
MMAR_1139|M.marinum_M GGNFNLGFGNGGAANVGVGNGGGGNMGFGNSGTENTGSFNSGGDNGPNGG
MUL_0902|M.ulcerans_Agy99 GGNFNLGFGNGGAANVGVGNGGGGNLGFGNSGTENTGSFNSGGDNGRNGG
Mb3184c|M.bovis_AF2122/97 GGNTNFGFGNAGFQNMGHGNAGGVNVGSGNAGLANTGDFNSGGVVSGIGG
Rv3159c|M.tuberculosis_H37Rv AGFFNMGIGNAGNEDMGVGNGGSFNVGVGNAGNQSVG-FGNAGTLN----
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 LAPTTTKAAESAFKAMGSAVQSTGRGLLGSSS----GGHVTAQLGR----
TH_3113|M.thermoresistible__bu GGPSLPSGSSAPPAPTGSAAPTTGTAPGGAGSPPPAGHSVPPAPHS----
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGTA
MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL
MAB_4284c|M.abscessus_ATCC_199 GGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGV
MMAR_1139|M.marinum_M NTGSFNSGYVNTGFFNS--------------GSTNTGLFNAGSVNTGIGS
MUL_0902|M.ulcerans_Agy99 NTGSFNSGYVNTGFFNS--------------GSTNTGLFNAGSVNTGIGS
Mb3184c|M.bovis_AF2122/97 NTGSFNSGNLNTGFGNA--------------GDLNTGLFNSGDVNTGIGS
Rv3159c|M.tuberculosis_H37Rv -VGFANAGSINTGFANS--------------GSINTGGFDSGDRNTGFGS
MAV_4704|M.avium_104 ----------NLGFSNA--------------STAVTRPAGSGAVARGYTS
MLBr_01182|M.leprae_Br4923 ---AASIGSLRVPQTWT--------------TASQPVTAATRALSPARVA
TH_3113|M.thermoresistible__bu ---APPVGTSGPPYLIA--------------AQPAPGVARRSAGARRAAS
Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG
Mvan_1264|M.vanbaalenii_PYR-1 GVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSAG
MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG
MAB_4284c|M.abscessus_ATCC_199 GGGVSTGVGVGSHVGGG-----------ISESLGGSGSVGGSTAVGGGAH
.
MMAR_1139|M.marinum_M PDTQPGSISGFG---------------NTGAGVSGFNNSGDATSGFMNVA
MUL_0902|M.ulcerans_Agy99 PDTQPGSISGFG---------------NTGAGVSGFNNSGDATSGFMNVA
Mb3184c|M.bovis_AF2122/97 TVDQPGSVSGFG---------------NTGTSVSGFNNSGNLTSGFGNMN
Rv3159c|M.tuberculosis_H37Rv SVDQSVSSSGFG---------------NTGMNSSGFFNTGNVSAGYGNNG
MAV_4704|M.avium_104 ------RIAGFL---------------APRAPQ-----------------
MLBr_01182|M.leprae_Br4923 VATESESAPLLG---------------GGLPMAPMVPGGG----------
TH_3113|M.thermoresistible__bu IVEPAGSAAAAA---------------AARESAPIRRRRGQKDGLHGHRH
Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
Mvan_1264|M.vanbaalenii_PYR-1 SAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA
MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV
MAB_4284c|M.abscessus_ATCC_199 TGVGGGVNTGVG---------VGSHVGGGISESLGGSGSVGGSTAVGGGA
MMAR_1139|M.marinum_M TT-FGFTSGINNV----------GDYQVGLFNTGFGNAGIANS-------
MUL_0902|M.ulcerans_Agy99 TT-FGFASGINNV----------GDYQVGLFNTGFGNAGIANS-------
Mb3184c|M.bovis_AF2122/97 SNVFDSTSGFQNIGDANVGFFNSGNSNEGFFNTGMFNNGIYNS-------
Rv3159c|M.tuberculosis_H37Rv ----DVQSGINNT--------NSGGFNVGFYNSGAGTVGIANS-------
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 --------------------------------------SGTGG-------
TH_3113|M.thermoresistible__bu EHQQPASM----------------SAATAPSAAGIRVLGGAGR-------
Mflv_5091|M.gilvum_PYR-GCK GATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-------
Mvan_1264|M.vanbaalenii_PYR-1 GATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-------
MSMEG_0868|M.smegmatis_MC2_155 QAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKS
MAB_4284c|M.abscessus_ATCC_199 HTSAINDALGGSGSVGGSTAVGGGAHTSAINESMNSSINASHSSS-----
MMAR_1139|M.marinum_M -------------------------------GNATFGIANSGALSSGISN
MUL_0902|M.ulcerans_Agy99 -------------------------------GNATFGIANSGALSSGISN
Mb3184c|M.bovis_AF2122/97 -------------------------------GVASTGIANSGNASSGVAN
Rv3159c|M.tuberculosis_H37Rv -------------------------------GLQTTGIANSGTLNTGVAN
MAV_4704|M.avium_104 --------------------------------------------------
MLBr_01182|M.leprae_Br4923 -------------------------------VNTALRLQPRAFVMPRNPA
TH_3113|M.thermoresistible__bu -------------------------------ISRTRGSVPHAEITPGDPT
Mflv_5091|M.gilvum_PYR-GCK ----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG-
Mvan_1264|M.vanbaalenii_PYR-1 ----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG-
MSMEG_0868|M.smegmatis_MC2_155 GGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGN
MAB_4284c|M.abscessus_ATCC_199 -------------------------------MNESFGSSMGSHGAAGTGF
MMAR_1139|M.marinum_M SGTNSSGGFNTGDDQSGFFN-------
MUL_0902|M.ulcerans_Agy99 SGTNSSGGFNTGDDQSGFFN-------
Mb3184c|M.bovis_AF2122/97 SGDNSSGAFNQGDNQAGFFGQP-----
Rv3159c|M.tuberculosis_H37Rv TGDHSSGGFNQGSDQSGFFGQP-----
MAV_4704|M.avium_104 ---------------------------
MLBr_01182|M.leprae_Br4923 AG-------------------------
TH_3113|M.thermoresistible__bu EPSSPTDRAHRPAEPN-----------
Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GGNGGNGGNGGADGTPGTAGTTGANNP
MAB_4284c|M.abscessus_ATCC_199 EAQGHAQGHASETAHTTLPGAEHH---