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M. marinum M MMAR_1094 (-)

annotation: PPE family protein
coordinates: 1314278 - 1315420
length: 380

DFGILPPEINSARMYSGPGSSPLLTVASAWSGLAAELSATANDYETVISGLQSQGWVGPSSEAMANSIWP
YVAWLRATAAATEQSASKARIAASAYEAAFAATVPPPQIAANRAELTGLISTNVVGQNSAAIAAAEAQYG
EMWSQDAATMYAYAASCATATSLTPFVSPPQTTNPTAAATQAGTLSRAAATTTGTAQSTLSRLISEVPGV
LQALTSPLASAASSTAGPIERFLEWYAPFANFFYDTLGLPFFGAGITSFFAATAKTAGAIGPAAAAPAAT
VAATGAAEAVGAGPVSASLAQASTVGKLSVPHTWEGATPATSPTTASKFISDVIEPESVEAGGNVIGGVP
MPGPGKGSAGAGPRYGVRLTVMPHPPSAG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1094--100% (380)PPE family protein
M. marinum MMMAR_2516-e-10750.26% (392) PPE family protein
M. marinum MMMAR_1904-1e-9546.12% (399) PPE family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1731cPPE221e-12155.32% (385) PPE family protein
M. gilvum PYR-GCKMflv_0325-1e-3129.52% (376) PPE protein
M. tuberculosis H37RvRv1705cPPE221e-12155.06% (385) PPE family protein
M. leprae Br4923MLBr_01182-1e-5234.69% (418) PPE-family protein
M. abscessus ATCC 19977MAB_4783-4e-3229.35% (402) PPE family protein
M. avium 104MAV_2926-1e-8944.72% (407) PPE family protein
M. smegmatis MC2 155MSMEG_0619-5e-3029.51% (366) PPE family protein
M. thermoresistible (build 8)TH_3113-1e-3229.15% (398) PUTATIVE PPE protein
M. ulcerans Agy99MUL_5078-0.098.16% (380) PPE family protein
M. vanbaalenii PYR-1Mvan_0415-3e-3334.31% (274) PPE protein

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1094|M.marinum_M               -------------MDFGILPPEINSARMYSGPGSSPLLTVASAWSGLAAE
MUL_5078|M.ulcerans_Agy99           -------------MDFRILPPEINSARMYSGPGSSPLLTVASAWSGLAAE
Mb1731c|M.bovis_AF2122/97           -------------MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAE
Rv1705c|M.tuberculosis_H37Rv        -------------MDFGALPPEVNSGRMYCGPGSAPMVAAASAWNGLAAE
MAV_2926|M.avium_104                -----------MMLDYGTFPPEFNSARIYSGPGSGSLVAAASAWSSLAAE
MLBr_01182|M.leprae_Br4923          ------------MFDFAALSPETNSTRMYLGPGSSPILTAAAAWVVLAKE
Mflv_0325|M.gilvum_PYR-GCK          MTSPVASLAPVTSPVWMALPPEVHSTMLSSGPGPGSLLAAGVAWQSLSAE
Mvan_0415|M.vanbaalenii_PYR-1       ----------MSSPVWMALPPEVHSALLSSGPGPGSMLAAAATWQSLSAE
MSMEG_0619|M.smegmatis_MC2_155      ----------MTAPIWMALPPEVHSSLLSSGPGPGSLLAAAGAWQSLSAE
MAB_4783|M.abscessus_ATCC_1997      ----------MTAPVWMAAPPEVHSALLSSGPGPGSLFAAADAWRSLSTE
TH_3113|M.thermoresistible__bu      ----------------MALPPEVHSTLLRTGPGPGALSAAADAWRMLSDE
                                                       .** :*  :  ***...: :.. :*  *: *

MMAR_1094|M.marinum_M               LSATANDYETVISGLQSQGWVGPSSEAMANSIWPYVAWLRATAAATEQSA
MUL_5078|M.ulcerans_Agy99           LSATANDYETVISGLQSQGWVGPSSEAMANSIWPYVAWLRATAAATEQSA
Mb1731c|M.bovis_AF2122/97           LSVAAVGYERVITTLQTEEWLGPASTLMVEAVAPYVAWMRATAIQAEQAA
Rv1705c|M.tuberculosis_H37Rv        LSVAAVGYERVITTLQTEEWLGPASTLMVEAVAPYVAWMRATAIQAEQAA
MAV_2926|M.avium_104                LNAAALSYDKVVTALASEEWLGSASASMASAVAPYVGWMSTTAAQAEEAA
MLBr_01182|M.leprae_Br4923          LTAAAQGLQSAVEALLTT-FEGESAAALAERVTPYEKWLTQNAASAELTA
Mflv_0325|M.gilvum_PYR-GCK          YASAAAELTSILAGVQSGAWEGPSSQQYVAAHTPYLAWLAQQSAVSAATA
Mvan_0415|M.vanbaalenii_PYR-1       YAAAAAELSSILADVQAGAWEGPSSEQYVAAHTPYLAWLAQQSAAGAAAA
MSMEG_0619|M.smegmatis_MC2_155      YAAAAAELTSVLSAVQAGSWEGPSSEQYVAAHAPYLQWLAQQSANSAAAA
MAB_4783|M.abscessus_ATCC_1997      YSSAANELTTTLGSVRAGVWDGASAEQYQTAHVPYLSWLHETSAVSAGVA
TH_3113|M.thermoresistible__bu      YRAAAVELAAVVSQTCATAWEGVGADAYAAAHGPYLFWLTDTAAAAAAAG
                                       :*      :    :  : * .:        **  *:   :      .

MMAR_1094|M.marinum_M               SKARIAASAYEAAFAATVPPPQIAANRAELTGLISTNVVGQNSAAIAAAE
MUL_5078|M.ulcerans_Agy99           SKARIAASAYEAAFAATVPPPQIAANRAELTGLISTNVVGQNSAAIAAAE
Mb1731c|M.bovis_AF2122/97           SQARAAAAAYETAFAAIVPPPLIAANRARLTSLVTHNVFGQNTASIAATE
Rv1705c|M.tuberculosis_H37Rv        SQARAAAAAYETAFAAIVPPPLIAANRARLTSLVTHNVFGQNTASIAATE
MAV_2926|M.avium_104                SQARAAAAAYEAALAASVPPPLIAANRMQVSQLQATNVLGQNTPLIAQLE
MLBr_01182|M.leprae_Br4923          TQLTVAANAYETAFTMTVPPLMVFVNRAQACLLIMSNIFGQNSTAIAEKE
Mflv_0325|M.gilvum_PYR-GCK          VQHDTAAAAYTTALATMPTLPELALNHTTHAVLVGTNFLGINTIPIALNE
Mvan_0415|M.vanbaalenii_PYR-1       AQHEAAAAAYSTALATMPTLPELALNHTTHAVLVATNFLGINTIPIAMTE
MSMEG_0619|M.smegmatis_MC2_155      VQHETAAAAYSTALATMPTMAELALNHTMHGVLVATNFFGINTIPIALNE
MAB_4783|M.abscessus_ATCC_1997      AQTETAATAYSEALATMPTLGELAANHATHGALVATNFFGINTIPIAVNE
TH_3113|M.thermoresistible__bu      AQLEAAAAAHASALAAMPTMAELTANRTTHAALVATNFFGVNTIPIAVNE
                                     :   ** *:  *::   .   :  *:     *   *..* *:  **  *

MMAR_1094|M.marinum_M               AQYGEMWSQDAATMYAYAASCATATSLTPFVSPP----------------
MUL_5078|M.ulcerans_Agy99           AQYGEMWSQDAATMYAYAASCATATSVTPFVSPP----------------
Mb1731c|M.bovis_AF2122/97           AQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPP----------------
Rv1705c|M.tuberculosis_H37Rv        AQYAEMWAQDAMAMYGYAGSSATATKVTPFAPPP----------------
MAV_2926|M.avium_104                AQYGEYWAQDAAAMYSYAGQSASASKVTPFQKAP----------------
MLBr_01182|M.leprae_Br4923          AEYTEMWIQDAAAMTSYQASVLEAVGATKAFTAPPLGVNEVGLAQEVVEE
Mflv_0325|M.gilvum_PYR-GCK          ADYVRMWIQAATTMATYQSVSGAALAATPTSAPAPSVLLP--------GV
Mvan_0415|M.vanbaalenii_PYR-1       ADYVRMWIQAATTMATYQAVSGAALAATPTATPAPFVLAP--------GV
MSMEG_0619|M.smegmatis_MC2_155      ADYVRMWIQAATTMSTYQAVSGAAVAAAPVSAPAPFLLKP--------GV
MAB_4783|M.abscessus_ATCC_1997      ADYIRMWIQAATVMSTYQAVSESSVSAAPPTSPAPPVLSP--------DS
TH_3113|M.thermoresistible__bu      ADYARMWIQAATTMATYEAVASAAVSATPRTVAPPPILGA--------GT
                                    *:* . * * * .*  * .    :   :    ..                

MMAR_1094|M.marinum_M               ---QTTNPTAAATQAGTLSRAAATTTGTAQSTLSRLISEVP---------
MUL_5078|M.ulcerans_Agy99           ---QTTSPTAAATQAGTLARAAATTAGTAQSTLSRLISEVP---------
Mb1731c|M.bovis_AF2122/97           ---NTTSPSAAATQLSAVAKAAGTSAGAAQSAIAELIAHLP---------
Rv1705c|M.tuberculosis_H37Rv        ---NTTSPSAAATQLSAVAKAAGTSAGAAQSAIAELIAHLP---------
MAV_2926|M.avium_104                ---QVTNPSGQAAQSAAVSTATANSTSTNTTKALQSLAQPA---------
MLBr_01182|M.leprae_Br4923          VVEEVVEEVVEAEQAISQAALDQAVNEGMEATVVPQVDQQV---------
Mflv_0325|M.gilvum_PYR-GCK          GEAGRAAADMSAFAAQPMAAQAGAAFD-VSNIIADIIRLYG------EVL
Mvan_0415|M.vanbaalenii_PYR-1       GEAGRAAADVTAFAAQAQAAEAGSALD-LSNIIADLIRAYG------ELL
MSMEG_0619|M.smegmatis_MC2_155      GEAGSASASVQQMSAQATAAESGSSLD-LSSIISDLLNQYL------QGV
MAB_4783|M.abscessus_ATCC_1997      GAAART-------AAQDATKPPPIVPD-PNDPIEMLLKNS-------QHF
TH_3113|M.thermoresistible__bu      GESATAAITGAHVTAELRAAESRTLLDEINELIDRLFAPLFPPGFADALP
                                         .            :                 .             

MMAR_1094|M.marinum_M               -----------------------GVLQALTSPLASAASSTAGP-------
MUL_5078|M.ulcerans_Agy99           -----------------------GVLQALTSPLASAASSTAGP-------
Mb1731c|M.bovis_AF2122/97           -----------------------NTLLGLTSPLSSALTAAATPGW-----
Rv1705c|M.tuberculosis_H37Rv        -----------------------NTLLGLTSPLSSALTAAATPGW-----
MAV_2926|M.avium_104                -----------------------SSSTTATKAATTAASTTSTDPLSEIWF
MLBr_01182|M.leprae_Br4923          -----------------------NVDVATPQTAVPDSSSAAAPQLWG---
Mflv_0325|M.gilvum_PYR-GCK          RFLFEPIFNFLR-------DPIGNTFALITDFLTNPVQALITWGPFLLAV
Mvan_0415|M.vanbaalenii_PYR-1       RFLFEPIFDFLR-------DPLGNTIKLITDFLTNPAQALITWGPFLAAV
MSMEG_0619|M.smegmatis_MC2_155      PGG-QAILDFLK-------DPLGNLGRLLTDFMTNPAGALATWWPFLFGV
MAB_4783|M.abscessus_ATCC_1997      LGMYRALKGLIT-------DPVGTIVRIIIDFSTNPAAAIVTWTPLFYVF
TH_3113|M.thermoresistible__bu      DGLLGTLLAPLLPGATGDGPPMATIMSFLLMGLSNPAYLFPVLVYLLFTG
                                                                                      

MMAR_1094|M.marinum_M               -----------IERFLEWYAPFANFFYDTLGLPFFGAGITS---------
MUL_5078|M.ulcerans_Agy99           -----------IERFLEWYAPFANFFYDTLGLPFFGAGITS---------
Mb1731c|M.bovis_AF2122/97           -----------LEWFINWYLPISQLFYNTVGLPYFAIGIGN---------
Rv1705c|M.tuberculosis_H37Rv        -----------LEWFINWYLPISQLFYNTVGLPYFAIGIGN---------
MAV_2926|M.avium_104                LLTGQTTLPTSLGSAVNGYSPFASLFYNTEGLPYFSTGMAN---------
MLBr_01182|M.leprae_Br4923          ----------GFAQHLSPINDTLSMINNHAGMANAGLSLVN---------
Mflv_0325|M.gilvum_PYR-GCK          VYQA----VSWVGASILYPSLFLLPLLATT--LAIVAGVGQ---HLLSLL
Mvan_0415|M.vanbaalenii_PYR-1       AYQA----VSWVGASILYPSLLLLPLVATT--LAIVLGVGA---YLLENL
MSMEG_0619|M.smegmatis_MC2_155      AYQVFFNLVGWPTWGMIFASPFLIPALAALGITGLVLLIDH---VLNNPV
MAB_4783|M.abscessus_ATCC_1997      AYAA-----TFAVMGTPIYAAIMGPAAGISIPLAITLAS------LSQMP
TH_3113|M.thermoresistible__bu      VVHTTVAVSGMLAQLVPLMPALLPVAVAALGGLAGVWAGLSGLAGLAGLT
                                                                                      

MMAR_1094|M.marinum_M               --------------------FFAATAKTAGAIGPAAAAPAATVAATG---
MUL_5078|M.ulcerans_Agy99           --------------------LFAATAKTAGAIGPAAAAPAATVAATG---
Mb1731c|M.bovis_AF2122/97           --------------------SLITSWRALGWIGPEAAEAAAAAPAAV---
Rv1705c|M.tuberculosis_H37Rv        --------------------SLITSWRALGWIGPEAAEAAAAAPAAV---
MAV_2926|M.avium_104                --------------------TFTQIAKSVGAIGGAAPAAAKALPGLGGLG
MLBr_01182|M.leprae_Br4923          --------------------GMGSAMKSLAPTTTKAAESAFKAMGSAVQS
Mflv_0325|M.gilvum_PYR-GCK          NTPPAEEAAEEPAPAQSAPSRPDQQSFPATMSAPPPPSGAPIAANTVSAG
Mvan_0415|M.vanbaalenii_PYR-1       PAPAEDAPAEEPAASSPAPTRADQPSPAIAVSAPPPPSSAAATVGTVATG
MSMEG_0619|M.smegmatis_MC2_155      DVPAEDEAPQEVAAAP----RTDQP-LAVGISPAGVPGSAATAAAPAPAP
MAB_4783|M.abscessus_ATCC_1997      EAPPVDAPAETVPARIDQPHAVAMGGAPAPTASTAAP--TPTTTSPATPG
TH_3113|M.thermoresistible__bu      AVPAADGGASAAPVPAGGPSLPSGSSAPPAPTGSAAPTTGTAPGGAGSPP
                                                               .        .             

MMAR_1094|M.marinum_M               ------------AAEAVGAGPVSASLAQASTVGKLSVPHTWEGATPATSP
MUL_5078|M.ulcerans_Agy99           ------------AAEAVGAGPVSASLAQASTVGKLSVPHTWEGATPATSP
Mb1731c|M.bovis_AF2122/97           ------------GAAVGGTGPVSAGLGNAATIGKLSVPPNWAGASPSLAP
Rv1705c|M.tuberculosis_H37Rv        ------------GAAVGGTGPVSAGLGNAATIGKLSLPPNWAGASPSLAP
MAV_2926|M.avium_104                GML---------GGGAAAAHPVAALGGAGSIGGKLSVPVAWSGAPATPAL
MLBr_01182|M.leprae_Br4923          TGRG--------LLGSSSGGHVTAQLGRAASIGSLRVPQTWTTASQPVTA
Mflv_0325|M.gilvum_PYR-GCK          SP-----PAPGAPAAAAATFVPYVVAGRDPYEGFSPTVRDSTGAKAPAGT
Mvan_0415|M.vanbaalenii_PYR-1       TA-----PAPGAPAAATASFVPYAVAGRDPGTGFSPTVRDSTSAKAPASG
MSMEG_0619|M.smegmatis_MC2_155      AG-----TTVAAPAPAAATFVPYAVANRDPGEGFTPTLGNKSQVAAPASG
MAB_4783|M.abscessus_ATCC_1997      SA-----PAP-TPPPAGAEGLGYAVRGDGPGFGFGPTIGASTGATAHAPS
TH_3113|M.thermoresistible__bu      PAGHSVPPAPHSAPPVGTSGPPYLIAAQ-PAPGVARRSAGARRAASIVEP
                                                                 .  *          .      

MMAR_1094|M.marinum_M               TTASK---FISDVIEPESVEAG-GNVIGG---------------------
MUL_5078|M.ulcerans_Agy99           TTASK---FISDVIEPESVEAG-GNVIGG---------------------
Mb1731c|M.bovis_AF2122/97           TVGSASAPLVSDIVEQPEAGAA-GNLLGG---------------------
Rv1705c|M.tuberculosis_H37Rv        TVGSASAPLVSDIVEQPEAGAA-GNLLGG---------------------
MAV_2926|M.avium_104                GHAIP----VSSISAAPEAAGGPGNLLGG---------------------
MLBr_01182|M.leprae_Br4923          ATRALSPARVAVATESESAPLLGGGLPMA---------------------
Mflv_0325|M.gilvum_PYR-GCK          IPAAASGIAASAAERRKRRRRQKEEIKGRGYADAYADYEELPDDGPPEQP
Mvan_0415|M.vanbaalenii_PYR-1       IPAAASGVAASAAERRKRRRRQKDEIAGRAYADAYADYEPEPDDEPPVRQ
MSMEG_0619|M.smegmatis_MC2_155      VPAAASGVAASLASRRKRRRKKGAQIEERGYADAYMDYEE-PDEDPAPQP
MAB_4783|M.abscessus_ATCC_1997      SAVSAAAALACNPATGKSRRRRRRTIDDRGYRHEYATMDDHTPTGP--QD
TH_3113|M.thermoresistible__bu      AGSAAAAAAARESAPIRRRRGQKDGLHGHRHEHQQPASMS----------
                                                             :                        

MMAR_1094|M.marinum_M               ---VPMPGPGKG--SAGAGPRYGVRLTVMPHPPSAG--------------
MUL_5078|M.ulcerans_Agy99           ---VPMPGPGEG--SAGAGPRYGVRLTVMPHPPSAG--------------
Mb1731c|M.bovis_AF2122/97           ---MPLAGSGTG--TGGAGPRYGFRVTVMSRPPFAG--------------
Rv1705c|M.tuberculosis_H37Rv        ---MPLAGSGTG--TGGAGPRYGFRVTVMSRPPFAG--------------
MAV_2926|M.avium_104                ---MPLAGAGAGG-HGAAGPKYGFRPTVMARPPFAG--------------
MLBr_01182|M.leprae_Br4923          ---PMVPGGGSGTGGVNTALRLQPRAFVMPRNPAAG--------------
Mflv_0325|M.gilvum_PYR-GCK          APRVTASTRGAGPMGFAGTVSRG-DEQAGGLTTLAGDSFGGGPREPMLPG
Mvan_0415|M.vanbaalenii_PYR-1       EPRIAATERGAGPMGFAGTVSRD-AAQAGGLTTLPGDPFGGGPKAPMLPG
MSMEG_0619|M.smegmatis_MC2_155      EPRVRASERGSDAMGFTGTVTRH-DVTAAGLTTLTGDTFDDRPVTPMLPG
MAB_4783|M.abscessus_ATCC_1997      PVTAVASGTGAGRLGFAGVHTATTAVEATGLSTLDGDAEN--RTIPMLPG
TH_3113|M.thermoresistible__bu      -AATAPSAAGIRVLGGAGRISRT-RGSVPHAEITPGDPTE--PSSPTDRA
                                          .  *                 .       *              

MMAR_1094|M.marinum_M               ---------------------------
MUL_5078|M.ulcerans_Agy99           ---------------------------
Mb1731c|M.bovis_AF2122/97           ---------------------------
Rv1705c|M.tuberculosis_H37Rv        ---------------------------
MAV_2926|M.avium_104                ---------------------------
MLBr_01182|M.leprae_Br4923          ---------------------------
Mflv_0325|M.gilvum_PYR-GCK          TWDPDATDDRHTDGRDGHDGHDGKEKP
Mvan_0415|M.vanbaalenii_PYR-1       TWDPDTEPD------ERHNHHDGKDSQ
MSMEG_0619|M.smegmatis_MC2_155      TWDGDENPAP------SPDDPEGGPRR
MAB_4783|M.abscessus_ATCC_1997      TWDVTDDDR------------------
TH_3113|M.thermoresistible__bu      HRPAEPN--------------------