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AASGIPDLSALLAWPTDHLTEAAAHWDNVGEHTYAVAHQLWRDATSIDWSGHAAGALRAATHADLQTTSA AVDQLQEAARVARNGASDLYAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFAG DLRQRAAQLVGLDAQVATKVTAAVAGIGSSFPQIPAPAAPPMGNPVRAVDNRTFKQNPPPAPVDPKDMTA EEARAAWADINSEIGKYNARCGRTFVLPTEQGAYDACIADKGPLLDRQAAIRARLGQLGIPVEGEDPTHP GTAEPPFPPPTRINGLTEHGAQRVEGRDGHGVNDNAMQDAVAHPIEPPQFMPDQYGGTWRYIGKDATVSL NENGQVTTAWANSRNGWRNP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0482 | - | - | 100% (371) | hypothetical protein MMAR_0482 |
| M. marinum M | MMAR_3572 | - | 2e-60 | 46.75% (308) | hypothetical protein MMAR_3572 |
| M. marinum M | MMAR_0116 | - | 1e-40 | 46.86% (207) | hypothetical protein MMAR_0116 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1984c | - | 9e-66 | 47.88% (307) | hypothetical protein Mb1984c |
| M. gilvum PYR-GCK | Mflv_1972 | - | 8e-14 | 24.93% (369) | hypothetical protein Mflv_1972 |
| M. tuberculosis H37Rv | Rv1949c | - | 4e-69 | 47.38% (325) | hypothetical protein Rv1949c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0016 | - | 7e-14 | 31.41% (156) | hypothetical protein MAB_0016 |
| M. avium 104 | MAV_3143 | - | 2e-69 | 62.56% (211) | hypothetical protein MAV_3143 |
| M. smegmatis MC2 155 | MSMEG_5600 | - | 1e-27 | 31.27% (307) | hypothetical protein MSMEG_5600 |
| M. thermoresistible (build 8) | TH_3926 | - | 2e-19 | 34.13% (167) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. ulcerans Agy99 | MUL_1133 | - | 0.0 | 99.36% (314) | hypothetical protein MUL_1133 |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | 2e-17 | 32.35% (170) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA
Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD
Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ
MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ
MMAR_0482|M.marinum_M -------MAASGIPDLSALLAWPTDHLTEAAAHWDNVGEHTYAVAHQLWR
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
Mb1984c|M.bovis_AF2122/97 --------------------------------------------------
Rv1949c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3143|M.avium_104 ---------MAGFPDLSQVLAWPTQHLTDAARHWEAVGERSYSVIHQVWR
MAB_0016|M.abscessus_ATCC_1997 ------------MPTKSEILNWRTDHLGAAAKTWGDQATQLDTAVNGAQG
TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAAMV
Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGSAI
Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDI
MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSADI
MMAR_0482|M.marinum_M DATS---IDWSGHAAGALRAATHADLQTTSAAVDQLQEAARVARNGASDL
MUL_1133|M.ulcerans_Agy99 -----------------MRAATHADLQTTSAAVDQLQEAARVARNGASDL
Mb1984c|M.bovis_AF2122/97 -----------------------------------MRQASGLAREGAGTI
Rv1949c|M.tuberculosis_H37Rv ----------------WLRQRTGADLQIVSGIAEHLRQASGLAREGAGTI
MAV_3143|M.avium_104 DGLS---SDWRGRAADALHAATHDDAGKTSGVADQLRAAAGVARSGASEL
MAB_0016|M.abscessus_ATCC_1997 ---LLDGLRGSGQFVEAFRTRLKSYIDKTRPKVDKLKSAKQVAESSEQQL
. * . :
TH_3926|M.thermoresistible__bu DQAKEEALLVVRVAGALAFDVREDLSLVDRLATGSPAATAVRLQQSNVLA
Mvan_5711|M.vanbaalenii_PYR-1 EAAKHEALTVIAATNAMGFEVADDLTVWNRMG------AALRRNDAELLG
Mflv_1972|M.gilvum_PYR-GCK QGARSRVLEAIAEAEQDDFTVGEDLSVTDNRAYDLET-AAARMTAATEHA
MSMEG_5600|M.smegmatis_MC2_155 SAAKRDALQSISDAEADGFEVNEDLSVRDTSRVDVST-MAARYTAAREHA
MMAR_0482|M.marinum_M YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA
MUL_1133|M.ulcerans_Agy99 YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA
Mb1984c|M.bovis_AF2122/97 GAAQRRVIYAVQDAHNAGFNVEEDLSVTDTRTSRTFAEQAARQAQAQALA
Rv1949c|M.tuberculosis_H37Rv GAAQRRVIYAVQDAHNAGFNVEEDLSVTDTRTSRTFAEQAARQAQAQALA
MAV_3143|M.avium_104 VAARSRVRYAVEDAMRSGFDVYEDMSVADRSTGGSAAQRAARQAQAQAFA
MAB_0016|M.abscessus_ATCC_1997 KGAKDKAVYAVHDPEDEDFNVNEDLSVTERRS-HSGLDRLKRAIRRRWLQ
*: . : . * * :*::: : *
TH_3926|M.thermoresistible__bu ATVRVGAAQLVSTDHAVAQRLREATDDFDSFD------FAR---------
Mvan_5711|M.vanbaalenii_PYR-1 ISVRTGAAQLAAVDHAVATELDSVTAGFDALN------IGE---------
Mflv_1972|M.gilvum_PYR-GCK EFIRWRVEQLVATDALIGQQLQANAAELEGIR------FEGDRDGNGTDP
MSMEG_5600|M.smegmatis_MC2_155 ENIQWNANQLLATDTLIGRRLTAKAAELNGVR------FDDEPEG-----
MMAR_0482|M.marinum_M GDLRQRAAQLVGLDAQVATKVTAAVAGIGSS-------FPQIPAPAAPP-
MUL_1133|M.ulcerans_Agy99 GDLPQRAAQLVGLDAQVATKVTAAVAGIGSS-------FPQIPAPAAPP-
Mb1984c|M.bovis_AF2122/97 GDIRQRATQLIGVEHEVAAKIATATAPLNTVGFHEPPIAPSLPTPVPHN-
Rv1949c|M.tuberculosis_H37Rv GDIRQRATQLIGVEHEVAAKIATATAPLNTVGFHEPPIAPSLPTPVPHN-
MAV_3143|M.avium_104 GDIRRRAAELVALDQQVAGRVTAATAGIRDT-------FPQTPDSDAPQ-
MAB_0016|M.abscessus_ATCC_1997 GILHTRAQELVATDNAIARKLHEIAQDLSNFHLEGPDGNTDFSGDPNHPK
: . :* . : :. .: . :
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK TIRLVDNKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAESAEG
MSMEG_5600|M.smegmatis_MC2_155 ------------------------------------------TIRAASFG
MMAR_0482|M.marinum_M ---------------------------------------MGNPVRAVDNR
MUL_1133|M.ulcerans_Agy99 ---------------------------------------MGNPVRAVDNR
Mb1984c|M.bovis_AF2122/97 ---------------------------------------EKPQIHAVD-R
Rv1949c|M.tuberculosis_H37Rv ---------------------------------------EKPQIHAVD-R
MAV_3143|M.avium_104 ---------------------------------------RKPKFQAVDHH
MAB_0016|M.abscessus_ATCC_1997 IMG--------------------------PAKPLGPIEQEDYDLGYTFLD
TH_3926|M.thermoresistible__bu -----NPIIQPLSTDSDEHHFGTCFAESFKEDVG----------------
Mvan_5711|M.vanbaalenii_PYR-1 -----GPVIAPIAAGDDGQSFGQCFADRFKDDIG----------------
Mflv_1972|M.gilvum_PYR-GCK ADTAESPLEALLGEGETAEGQQRSSLDEALTEVAGKPVDAPPTALERILS
MSMEG_5600|M.smegmatis_MC2_155 DGFKQSPFDDLLT-----KEQALAAWEKLQTDIASYNSRCAVNIVG----
MMAR_0482|M.marinum_M TFKQNPP-PAPVDPKDMTAEEARAAWADINSEIGKYNARCGRT-------
MUL_1133|M.ulcerans_Agy99 TFKQNPP-PAPVDPKDMTAEEARAAWADINSEIGKYNARCGRT-------
Mb1984c|M.bovis_AF2122/97 SWKQDPPSPMPGDPKDMTAVQARAAWDAVNADIARYNARCGRT-------
Rv1949c|M.tuberculosis_H37Rv SWKQDPPSPMPGDPKDMTAVQARAAWDAVNADIARYNARCGRT-------
MAV_3143|M.avium_104 TFKEDPPPNGSYPVNEVVAEATDLDGNHVVLRRGYYNAEKREG-------
MAB_0016|M.abscessus_ATCC_1997 ENGNPLPMLDENGNVVIDPKTGRPVPDSVWGDPADNNADGSPR-------
* .
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK QHTGTGRGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESAQGA
MSMEG_5600|M.smegmatis_MC2_155 ----------------PLPPPQYAACQQELAFLQG---------------
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
Mb1984c|M.bovis_AF2122/97 --------------------------------------------------
Rv1949c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3143|M.avium_104 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3926|M.thermoresistible__bu --KNMVQGVFVGGAIGAAR--------------------GALMGILGGPI
Mvan_5711|M.vanbaalenii_PYR-1 --ENMVQGVFVGGALGALR--------------------GAVLGVLGGPL
Mflv_1972|M.gilvum_PYR-GCK LDDALAQSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLNAAA
MSMEG_5600|M.smegmatis_MC2_155 -QEAALRARLADFGIHPG----------------EAPSSTSSGGDLTATA
MMAR_0482|M.marinum_M FVLPTEQGAYDACIADKGP-------------------LLDRQAAIRARL
MUL_1133|M.ulcerans_Agy99 FVLPTEQGAYDACIADKGP-------------------LLDRQAVIRARL
Mb1984c|M.bovis_AF2122/97 FVLPNEQAAYDACIADKGS-------------------LLERQAAIRARL
Rv1949c|M.tuberculosis_H37Rv FVLPNEQAAYDACIADKGS-------------------LFERQAAIRARL
MAV_3143|M.avium_104 WGW--DKAYWRHGVVNPNV-------------------FKDLISHSRPEH
MAB_0016|M.abscessus_ATCC_1997 VPHPPRDHHFADMDANDPYR---------------TLPTGTTVGPNGERI
TH_3926|M.thermoresistible__bu GVFG------------GGVLGFVGGAAGGALIS-------------GPAR
Mvan_5711|M.vanbaalenii_PYR-1 GMLG------------GSVAGFVGGAAGGAMIS-------------GPAR
Mflv_1972|M.gilvum_PYR-GCK DEVGQGRVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDVAHD
MSMEG_5600|M.smegmatis_MC2_155 TQIG------------AEIATFPPGTRADALAERMTGLHLNQADAARATD
MMAR_0482|M.marinum_M GQLGIPVEGEDPTHPGTAEPPFPPPTRINGLTEHGAQR-VEGRDGHGVND
MUL_1133|M.ulcerans_Agy99 GQLGIPVEGEDPTHPGTAEPPFPPPTRINGLTEHGAQR-VEGRDGHGVND
Mb1984c|M.bovis_AF2122/97 GELGVPVEGEPPPAP---DPAGPQPN--EGLPPPGVSPPAESNLTVGPPS
Rv1949c|M.tuberculosis_H37Rv GELGVPVEGEPPPAP---DPAGPQPN--EGLPPPGVSPPAESNLTVGPPS
MAV_3143|M.avium_104 QPDGTLRYDVLINRVHCASGPLGIASCQDTGESLTMRIVVDPRVGRADVP
MAB_0016|M.abscessus_ATCC_1997 ALVSRPPDDPAWAENQTKNGKSVYVTQTEAYDVTRQPPQSLGKLQGVDGS
.
TH_3926|M.thermoresistible__bu TAVTSAWDCL----------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 TAVTSAWDCL----------------------------------------
Mflv_1972|M.gilvum_PYR-GCK IDVFRNWSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEHAVDAVNAGR
MSMEG_5600|M.smegmatis_MC2_155 IAAARIWGETG------------GTSKMPDGSIIVLPANIRQTDVMKVFP
MMAR_0482|M.marinum_M NAMQDAVAHPIEPP--------QFMPDQYGGTWRYIGKD----ATVSLNE
MUL_1133|M.ulcerans_Agy99 NAMQDAVAHPIEPP--------QFMPDQYGGTWRYIGKD----ATVSLNE
Mb1984c|M.bovis_AF2122/97 RPIQQARGG-------------ESLWDENGGEWRYFPGDNYRYPHWDYNP
Rv1949c|M.tuberculosis_H37Rv RPIQQARGG-------------ESLWDENGGEWRYFPGDNYRYPHWDYNP
MAV_3143|M.avium_104 GGEQKGVIT---------------MFPLEGGSG-----------VIQLGP
MAB_0016|M.abscessus_ATCC_1997 KVYQGSIVYDKASG------RMYVVGNHGDGSGDTARGMWRSDPVDPNHP
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK HVDDALDAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGNFGF
MSMEG_5600|M.smegmatis_MC2_155 DGSVTVLRGVDVTQYLPR--------------------------------
MMAR_0482|M.marinum_M NGQVTTAWANSRNGWRNP--------------------------------
MUL_1133|M.ulcerans_Agy99 NGQVTTAWANSRNGWRNP--------------------------------
Mb1984c|M.bovis_AF2122/97 HDSPTARWQNIPIGDLPTHK------------------------------
Rv1949c|M.tuberculosis_H37Rv HDSPTARWQNIPIGDLPTHK------------------------------
MAV_3143|M.avium_104 KWTWTPPWVNNNVPIN----------------------------------
MAB_0016|M.abscessus_ATCC_1997 NDWVKTLRYQGDVPSLPGSRESSLVALPHGGVALFGADDYAPAEGRNMAV
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK EDANALLQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATADEA
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
Mb1984c|M.bovis_AF2122/97 --------------------------------------------------
Rv1949c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3143|M.avium_104 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 GAISAATPEGLLQARPVTDLLPAGKTPWPGGAPYAALPTGVHWDPALRAD
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK ASAVSTALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAVTGS
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
Mb1984c|M.bovis_AF2122/97 --------------------------------------------------
Rv1949c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3143|M.avium_104 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 VVDTRVSIWRDVPGVRGAYPPVTYQTSVPIFQPNS---------------
TH_3926|M.thermoresistible__bu -----------------------
Mvan_5711|M.vanbaalenii_PYR-1 -----------------------
Mflv_1972|M.gilvum_PYR-GCK TVRVVLKGDGNGGWYVLTGFPKP
MSMEG_5600|M.smegmatis_MC2_155 -----------------------
MMAR_0482|M.marinum_M -----------------------
MUL_1133|M.ulcerans_Agy99 -----------------------
Mb1984c|M.bovis_AF2122/97 -----------------------
Rv1949c|M.tuberculosis_H37Rv -----------------------
MAV_3143|M.avium_104 -----------------------
MAB_0016|M.abscessus_ATCC_1997 -----------------------