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MAAAIGSLPTLSNLMAWPTEHLTEAAASWTAAGHRWYEVFNQIWRDSLSVDWKGIGADALHTRTHADHTK VSGLVDQLHEAARIARVGASDLYAARSRVRYAVEDAHDAGFVVGEDLSVTDYSTGGSLVERATRQAQAQA LAADIRQRAGLLISLDGQLAGKVTTAMAGIGNVFPADNPTTTTTPPPLPPARCDPEDVAELMQKVDEWNQ RDAQLTDEINAYNREKRDFNLNDPEERRKAADYIRRGQELQAKKDKLLDDQRDLIREVTECGAKIVDSHI EWPNGSTSPTPSPTPTPTPTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3572 | - | - | 100% (301) | hypothetical protein MMAR_3572 |
| M. marinum M | MMAR_0482 | - | 1e-60 | 46.75% (308) | hypothetical protein MMAR_0482 |
| M. marinum M | MMAR_0116 | - | 1e-40 | 49.72% (177) | hypothetical protein MMAR_0116 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2102c | - | 1e-41 | 44.88% (205) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1972 | - | 4e-15 | 32.97% (182) | hypothetical protein Mflv_1972 |
| M. tuberculosis H37Rv | Rv2077c | - | 1e-41 | 44.88% (205) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0016 | - | 6e-12 | 28.41% (176) | hypothetical protein MAB_0016 |
| M. avium 104 | MAV_3143 | - | 8e-55 | 60.82% (171) | hypothetical protein MAV_3143 |
| M. smegmatis MC2 155 | MSMEG_5600 | - | 3e-12 | 29.31% (174) | hypothetical protein MSMEG_5600 |
| M. thermoresistible (build 8) | TH_3926 | - | 2e-18 | 32.04% (181) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. ulcerans Agy99 | MUL_1133 | - | 3e-40 | 44.84% (252) | hypothetical protein MUL_1133 |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | 5e-15 | 30.86% (175) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA
Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD
MAV_3143|M.avium_104 ---------MAGFPDLSQVLAWPTQHLTDAARHWEAVGERSYSVIHQVWR
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3572|M.marinum_M -----MAAAIGSLPTLSNLMAWPTEHLTEAAASWTAAGHRWYEVFNQIWR
Mb2102c|M.bovis_AF2122/97 -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
Rv2077c|M.tuberculosis_H37Rv -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ
MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ
MAB_0016|M.abscessus_ATCC_1997 ------------MPTKSEILNWRTDHLGAAAKTWGDQATQLDTAVNGAQG
TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAAMV
Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGSAI
MAV_3143|M.avium_104 DGLS---SDWRGRAADALHAATHDDAGKTSGVADQLRAAAGVARSGASEL
MUL_1133|M.ulcerans_Agy99 -----------------MRAATHADLQTTSAAVDQLQEAARVARNGASDL
MMAR_3572|M.marinum_M DSLS---VDWKGIGADALHTRTHADHTKVSGLVDQLHEAARIARVGASDL
Mb2102c|M.bovis_AF2122/97 QAHA---IAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
Rv2077c|M.tuberculosis_H37Rv QAHA---IAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDI
MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSADI
MAB_0016|M.abscessus_ATCC_1997 LLDG---LRGSGQFVEAFRTRLKSYIDKTRPKVDKLKSAKQVAESSEQQL
. : . * . :
TH_3926|M.thermoresistible__bu DQAKEEALLVVRVAGALAFDVREDLSLVDRLATGSPAATAVRLQQSNVLA
Mvan_5711|M.vanbaalenii_PYR-1 EAAKHEALTVIAATNAMGFEVADDLTVWNRMG------AALRRNDAELLG
MAV_3143|M.avium_104 VAARSRVRYAVEDAMRSGFDVYEDMSVADRSTGGSAAQRAARQAQAQAFA
MUL_1133|M.ulcerans_Agy99 YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA
MMAR_3572|M.marinum_M YAARSRVRYAVEDAHDAGFVVGEDLSVTDYSTGGSLVERATRQAQAQALA
Mb2102c|M.bovis_AF2122/97 DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
Rv2077c|M.tuberculosis_H37Rv DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
Mflv_1972|M.gilvum_PYR-GCK QGARSRVLEAIAEAEQDDFTVGEDLSVTDNRA-YDLETAAARMTAATEHA
MSMEG_5600|M.smegmatis_MC2_155 SAAKRDALQSISDAEADGFEVNEDLSVRDTSR-VDVSTMAARYTAAREHA
MAB_0016|M.abscessus_ATCC_1997 KGAKDKAVYAVHDPEDEDFNVNEDLSVTERRS-HSGLDRLKRAIRRRWLQ
*: . : . * * :*::: : *
TH_3926|M.thermoresistible__bu ATVRVGAAQLVSTDHAVAQRLREATDDFDSFDFA----------------
Mvan_5711|M.vanbaalenii_PYR-1 ISVRTGAAQLAAVDHAVATELDSVTAGFDALNIG----------------
MAV_3143|M.avium_104 GDIRRRAAELVALDQQVAGRVTAATAGIRDTFPQTPDSDAPQ--------
MUL_1133|M.ulcerans_Agy99 GDLPQRAAQLVGLDAQVATKVTAAVAGIGSSFPQIPAPAAPP--------
MMAR_3572|M.marinum_M ADIRQRAGLLISLDGQLAGKVTTAMAGIGNVFP-----------------
Mb2102c|M.bovis_AF2122/97 GDIRLRVGQLVAAENEVSGQLAATTGDVGNVRFAGAPVVAHS--------
Rv2077c|M.tuberculosis_H37Rv GDIRLRVGQLVAAENEVSGQLAATTGDVGNVRFAGAPVVAHS--------
Mflv_1972|M.gilvum_PYR-GCK EFIRWRVEQLVATDALIGQQLQANAAELEGIRFEGDRDGNGTDPTIRLVD
MSMEG_5600|M.smegmatis_MC2_155 ENIQWNANQLLATDTLIGRRLTAKAAELNGVRFDDEPEG-----------
MAB_0016|M.abscessus_ATCC_1997 GILHTRAQELVATDNAIARKLHEIAQDLSNFHLEGPDGNTDFSGDPNHPK
: . * . : :. .: .
TH_3926|M.thermoresistible__bu ------------------------------------------------RN
Mvan_5711|M.vanbaalenii_PYR-1 ------------------------------------------------EG
MAV_3143|M.avium_104 ---------------------------------RKPKFQAVDHHTFKEDP
MUL_1133|M.ulcerans_Agy99 ---------------------------------MGNPVRAVDNRTFKQNP
MMAR_3572|M.marinum_M ----------------------------------------ADNPTTTTTP
Mb2102c|M.bovis_AF2122/97 ---------------------------------AVQLVDFFKQDGPTPPP
Rv2077c|M.tuberculosis_H37Rv ---------------------------------AVQLVDFFKQDGPTPPP
Mflv_1972|M.gilvum_PYR-GCK NKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAESAEGADTAES
MSMEG_5600|M.smegmatis_MC2_155 ------------------------------------TIRAASFGDGFKQS
MAB_0016|M.abscessus_ATCC_1997 IMGPAKPLG--------------------PIEQEDYDLGYTFLDENGNPL
TH_3926|M.thermoresistible__bu PIIQPLSTDSDEHHFGTCFAESFKEDVGKNMVQG----------------
Mvan_5711|M.vanbaalenii_PYR-1 PVIAPIAAGDDGQSFGQCFADRFKDDIGENMVQG----------------
MAV_3143|M.avium_104 PPNGSYPVNEVVAEATDLDGNHVVLRRGYYNAEK----------------
MUL_1133|M.ulcerans_Agy99 PPAPVDPK-DMTAEEARAAWADINSEIGKYNARCGRTFVL----------
MMAR_3572|M.marinum_M PPLP-------PARCDPEDVAELMQKVDEWNQRD----------------
Mb2102c|M.bovis_AF2122/97 PGAPHPSGGADGPYSDPITSMMLPPAGTEAPVSD----------------
Rv2077c|M.tuberculosis_H37Rv PGAPHPSGGADGPYSDPITSMMLPPAGTEAPVSD----------------
Mflv_1972|M.gilvum_PYR-GCK PLEALLGEGETAEGQQRSSLDEALTEVAGKPVDAPPTALERILSQHTGTG
MSMEG_5600|M.smegmatis_MC2_155 PFDDLLT-----KEQALAAWEKLQTDIASYNSRCAVNIVG----------
MAB_0016|M.abscessus_ATCC_1997 PMLDENGNVVIDPKTGRPVPDSVWGDPADNNADGSPRVPHP---------
*
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3143|M.avium_104 -----------REGWGWDKAYWRHG-----------------------VV
MUL_1133|M.ulcerans_Agy99 ----------PTEQGAYDACIADKGPLLD----------------RQAVI
MMAR_3572|M.marinum_M --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK RGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESAQGALDDALA
MSMEG_5600|M.smegmatis_MC2_155 ----------PLPPPQYAACQQELAFLQG----------------QEAAL
MAB_0016|M.abscessus_ATCC_1997 -----------PRDHHFADMDANDPYRTLPTGTTVGPNGERIALVSRPPD
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3143|M.avium_104 NPNVFKDLISHS------------------RPEHQPDGTLRYDVLINR--
MUL_1133|M.ulcerans_Agy99 RARLGQLGIPVE------------------GEDPTHPGTAEPPFPPPT--
MMAR_3572|M.marinum_M -AQLTDEINAYN------------------REKRD----FNLNDPEER--
Mb2102c|M.bovis_AF2122/97 ATKRWVDNMVNE------------------LAARPPDDPIAVEARRLA--
Rv2077c|M.tuberculosis_H37Rv ATKRWVDNMVNE------------------LAARPPDDPIAVEARRLA--
Mflv_1972|M.gilvum_PYR-GCK QSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLNAAADEVGQG
MSMEG_5600|M.smegmatis_MC2_155 RARLADFGIHPG----------------EAPSSTSSGGDLTATATQIG--
MAB_0016|M.abscessus_ATCC_1997 DPAWAENQTKNGKS--------------VYVTQTEAYDVTRQPPQSLGKL
TH_3926|M.thermoresistible__bu ---------------------VFVGGAIGAARGALMGILGGPIGVFGGGV
Mvan_5711|M.vanbaalenii_PYR-1 ---------------------VFVGGALGALRGAVLGVLGGPLGMLGGSV
MAV_3143|M.avium_104 -----------VHCASGPLGIASCQDT-GESLTMRIVVDPRVGRADVPGG
MUL_1133|M.ulcerans_Agy99 -----------RINGLTEHGAQRVEGRDGHGVNDNAMQDAVAHPIEPPQF
MMAR_3572|M.marinum_M -----------RKAADYIRRGQELQAK-----KDKLLDDQRDLIREVTEC
Mb2102c|M.bovis_AF2122/97 -----------FQALHRPCNSAEWTAAVAGFAGSSAGVVGTALAIPAGPA
Rv2077c|M.tuberculosis_H37Rv -----------FQALHRPCNSAEWTAAVAGFAGSSAGVVGTALAIPAGPA
Mflv_1972|M.gilvum_PYR-GCK RVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDVAHDIDVFRN
MSMEG_5600|M.smegmatis_MC2_155 ----------AEIATFPPGTRADALAERMTGLHLNQADAARATDIAAARI
MAB_0016|M.abscessus_ATCC_1997 QGVDGSKVYQGSIVYDKASGRMYVVGNHGDGSGDTARGMWRSDPVDPNHP
TH_3926|M.thermoresistible__bu LGFVGG---------------------AAGGALISGPARTAVTSAWDCL-
Mvan_5711|M.vanbaalenii_PYR-1 AGFVGG---------------------AAGGAMISGPARTAVTSAWDCL-
MAV_3143|M.avium_104 EQKGVI----------------TMFPLEGGSGVIQLGPKWTWTPPWVNN-
MUL_1133|M.ulcerans_Agy99 MPDQYG----------------GTWRYIGKDATVSLNENGQVTTAWANSR
MMAR_3572|M.marinum_M GAKIVD----------------SHIEWPNGSTSPTPSPTPTPTPTR----
Mb2102c|M.bovis_AF2122/97 DWALLG----------------AALLGVGGSGAAVVNCATK---------
Rv2077c|M.tuberculosis_H37Rv DWALLG----------------AALLGVGGSGAAVVNCATK---------
Mflv_1972|M.gilvum_PYR-GCK WSEASSDDRA-----GAVLDVAGAAPIP-GGKLVTEGLEHAVDAVNAGRH
MSMEG_5600|M.smegmatis_MC2_155 WGETG-----------------GTSKMPDGSIIVLPANIRQTDVMKVFPD
MAB_0016|M.abscessus_ATCC_1997 NDWVKTLRYQGDVPSLPGSRESSLVALPHGGVALFGADDYAPAEGRNMAV
.
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3143|M.avium_104 NVPIN---------------------------------------------
MUL_1133|M.ulcerans_Agy99 NGWRNP--------------------------------------------
MMAR_3572|M.marinum_M --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK VDDALDAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGNFGFE
MSMEG_5600|M.smegmatis_MC2_155 GSVTVLRGVDVTQYLPR---------------------------------
MAB_0016|M.abscessus_ATCC_1997 GAISAATPEGLLQARPVTDLLPAGKTPWPGGAPYAALPTGVHWDPALRAD
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3143|M.avium_104 --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3572|M.marinum_M --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK DANALLQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATADEAA
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 VVDTRVSIWRDVPGVRGAYPPVTYQTSVPIFQPNS---------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_3143|M.avium_104 --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3572|M.marinum_M --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK SAVSTALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAVTGST
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 --------------------------------------------------
TH_3926|M.thermoresistible__bu ----------------------
Mvan_5711|M.vanbaalenii_PYR-1 ----------------------
MAV_3143|M.avium_104 ----------------------
MUL_1133|M.ulcerans_Agy99 ----------------------
MMAR_3572|M.marinum_M ----------------------
Mb2102c|M.bovis_AF2122/97 ----------------------
Rv2077c|M.tuberculosis_H37Rv ----------------------
Mflv_1972|M.gilvum_PYR-GCK VRVVLKGDGNGGWYVLTGFPKP
MSMEG_5600|M.smegmatis_MC2_155 ----------------------
MAB_0016|M.abscessus_ATCC_1997 ----------------------