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AGFPDLSQVLAWPTQHLTDAARHWEAVGERSYSVIHQVWRDGLSSDWRGRAADALHAATHDDAGKTSGVA DQLRAAAGVARSGASELVAARSRVRYAVEDAMRSGFDVYEDMSVADRSTGGSAAQRAARQAQAQAFAGDI RRRAAELVALDQQVAGRVTAATAGIRDTFPQTPDSDAPQRKPKFQAVDHHTFKEDPPPNGSYPVNEVVAE ATDLDGNHVVLRRGYYNAEKREGWGWDKAYWRHGVVNPNVFKDLISHSRPEHQPDGTLRYDVLINRVHCA SGPLGIASCQDTGESLTMRIVVDPRVGRADVPGGEQKGVITMFPLEGGSGVIQLGPKWTWTPPWVNNNVP IN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3143 | - | - | 100% (353) | hypothetical protein MAV_3143 |
| M. avium 104 | MAV_1108 | - | 1e-68 | 65.78% (187) | hypothetical protein MAV_1108 |
| M. avium 104 | MAV_1450 | - | 9e-37 | 48.95% (190) | hypothetical protein MAV_1450 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2102c | - | 1e-35 | 43.35% (203) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1972 | - | 7e-14 | 31.41% (191) | hypothetical protein Mflv_1972 |
| M. tuberculosis H37Rv | Rv2077c | - | 1e-35 | 43.35% (203) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0016 | - | 3e-13 | 29.14% (175) | hypothetical protein MAB_0016 |
| M. marinum M | MMAR_0482 | - | 2e-69 | 62.56% (211) | hypothetical protein MMAR_0482 |
| M. smegmatis MC2 155 | MSMEG_5600 | - | 8e-14 | 29.38% (160) | hypothetical protein MSMEG_5600 |
| M. thermoresistible (build 8) | TH_3926 | - | 6e-21 | 32.86% (210) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. ulcerans Agy99 | MUL_1133 | - | 2e-45 | 61.78% (157) | hypothetical protein MUL_1133 |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | 8e-17 | 33.13% (166) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0482|M.marinum_M -------MAASGIPDLSALLAWPTDHLTEAAAHWDNVGEHTYAVAHQLWR
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAV_3143|M.avium_104 ---------MAGFPDLSQVLAWPTQHLTDAARHWEAVGERSYSVIHQVWR
TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA
Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD
Mb2102c|M.bovis_AF2122/97 -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
Rv2077c|M.tuberculosis_H37Rv -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ
MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ
MAB_0016|M.abscessus_ATCC_1997 ------------MPTKSEILNWRTDHLGAAAKTWGDQATQLDTAVNGAQG
MMAR_0482|M.marinum_M ---DATSIDWSGHAAGALRAATHADLQTTSAAVDQLQEAARVARNGASDL
MUL_1133|M.ulcerans_Agy99 -----------------MRAATHADLQTTSAAVDQLQEAARVARNGASDL
MAV_3143|M.avium_104 ---DGLSSDWRGRAADALHAATHDDAGKTSGVADQLRAAAGVARSGASEL
TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAAMV
Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGSAI
Mb2102c|M.bovis_AF2122/97 ---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
Rv2077c|M.tuberculosis_H37Rv ---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDI
MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSADI
MAB_0016|M.abscessus_ATCC_1997 ---LLDGLRGSGQFVEAFRTRLKSYIDKTRPKVDKLKSAKQVAESSEQQL
. : . * . :
MMAR_0482|M.marinum_M YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA
MUL_1133|M.ulcerans_Agy99 YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA
MAV_3143|M.avium_104 VAARSRVRYAVEDAMRSGFDVYEDMSVADRSTGGSAAQRAARQAQAQAFA
TH_3926|M.thermoresistible__bu DQAKEEALLVVRVAGALAFDVREDLSLVDRLATGSPAATAVRLQQSNVLA
Mvan_5711|M.vanbaalenii_PYR-1 EAAKHEALTVIAATNAMGFEVADDLTVWNRMG------AALRRNDAELLG
Mb2102c|M.bovis_AF2122/97 DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
Rv2077c|M.tuberculosis_H37Rv DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
Mflv_1972|M.gilvum_PYR-GCK QGARSRVLEAIAEAEQDDFTVGEDLSVTDNRAYD-LETAAARMTAATEHA
MSMEG_5600|M.smegmatis_MC2_155 SAAKRDALQSISDAEADGFEVNEDLSVRDTSRVD-VSTMAARYTAAREHA
MAB_0016|M.abscessus_ATCC_1997 KGAKDKAVYAVHDPEDEDFNVNEDLSVTERRSHS-GLDRLKRAIRRRWLQ
*: . : . * * :*::: : *
MMAR_0482|M.marinum_M GDLRQRAAQLVGLDAQVATKVTAAVAGIGSSFPQIPAPA-----------
MUL_1133|M.ulcerans_Agy99 GDLPQRAAQLVGLDAQVATKVTAAVAGIGSSFPQIPAPA-----------
MAV_3143|M.avium_104 GDIRRRAAELVALDQQVAGRVTAATAGIRDTFPQTPDSD-----------
TH_3926|M.thermoresistible__bu ATVRVGAAQLVSTDHAVAQRLREATDDFDSFDFARN--------------
Mvan_5711|M.vanbaalenii_PYR-1 ISVRTGAAQLAAVDHAVATELDSVTAGFDALNIGEG--------------
Mb2102c|M.bovis_AF2122/97 GDIRLRVGQLVAAENEVSGQLAATTGDVGNVRFAG---------------
Rv2077c|M.tuberculosis_H37Rv GDIRLRVGQLVAAENEVSGQLAATTGDVGNVRFAG---------------
Mflv_1972|M.gilvum_PYR-GCK EFIRWRVEQLVATDALIGQQLQANAAELEGIRFEGDRDGNGTDPTIRLVD
MSMEG_5600|M.smegmatis_MC2_155 ENIQWNANQLLATDTLIGRRLTAKAAELNGVRFDDEPEG-----------
MAB_0016|M.abscessus_ATCC_1997 GILHTRAQELVATDNAIARKLHEIAQDLSNFHLEGPDGN-----------
: . :* . : :. .: . .
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAV_3143|M.avium_104 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK NKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAESAEGADTAES
MSMEG_5600|M.smegmatis_MC2_155 ------------------------------------TIRAASFGDGFKQS
MAB_0016|M.abscessus_ATCC_1997 --------------------------------------------------
MMAR_0482|M.marinum_M -------------APPMGNPVRAVDNRTFKQN------------------
MUL_1133|M.ulcerans_Agy99 -------------APPMGNPVRAVDNRTFKQN------------------
MAV_3143|M.avium_104 -------------APQRKPKFQAVDHHTFKED------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 -------------APVVAHSAVQLVDFFKQDG------------------
Rv2077c|M.tuberculosis_H37Rv -------------APVVAHSAVQLVDFFKQDG------------------
Mflv_1972|M.gilvum_PYR-GCK PLEALLGEGETAEGQQRSSLDEALTEVAGKPVDAPPTALERILSQHTGTG
MSMEG_5600|M.smegmatis_MC2_155 PFDDLLT-----KEQALAAWEKLQTDIASYNSRCAVNIVG----------
MAB_0016|M.abscessus_ATCC_1997 -----TDFSGDPNHPKIMGPAKPLGPIEQEDYDLGYTFLD----------
MMAR_0482|M.marinum_M ----------PPPAPVDPK-DMTAEE-------------------ARAAW
MUL_1133|M.ulcerans_Agy99 ----------PPPAPVDPK-DMTAEE-------------------ARAAW
MAV_3143|M.avium_104 ----------PPPNGSYPVNEVVAEA-------------------TDLDG
TH_3926|M.thermoresistible__bu ----------PIIQPLSTDS-------------------------DEHHF
Mvan_5711|M.vanbaalenii_PYR-1 ----------PVIAPIAAGD-------------------------DGQSF
Mb2102c|M.bovis_AF2122/97 ----------PTPPPPGAPHPSGG---------------------ADGPY
Rv2077c|M.tuberculosis_H37Rv ----------PTPPPPGAPHPSGG---------------------ADGPY
Mflv_1972|M.gilvum_PYR-GCK RGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESAQGALDDALA
MSMEG_5600|M.smegmatis_MC2_155 ----------PLPPPQYAACQQELAFLQG----------------QEAAL
MAB_0016|M.abscessus_ATCC_1997 --------ENGNPLPMLDENGNVVIDPKTG------------RPVPDSVW
MMAR_0482|M.marinum_M ADINSEIGKYNARCG-------------RTFVLPTEQGAYDACIADKGPL
MUL_1133|M.ulcerans_Agy99 ADINSEIGKYNARCG-------------RTFVLPTEQGAYDACIADKGPL
MAV_3143|M.avium_104 NHVVLRRGYYNAEK--------------------REGWGWDKAYWRHG--
TH_3926|M.thermoresistible__bu GTCFAESFKEDVG-------------------KNMVQGVFVG--------
Mvan_5711|M.vanbaalenii_PYR-1 GQCFADRFKDDIG-------------------ENMVQGVFVG--------
Mb2102c|M.bovis_AF2122/97 SDPITSMMLPPAG--------------TEAPVSDATKRWVDNMVNELAAR
Rv2077c|M.tuberculosis_H37Rv SDPITSMMLPPAG--------------TEAPVSDATKRWVDNMVNELAAR
Mflv_1972|M.gilvum_PYR-GCK QSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLNAAADEVGQG
MSMEG_5600|M.smegmatis_MC2_155 RARLADFGIHPG----------------EAPSSTSSGGDLTATATQIG--
MAB_0016|M.abscessus_ATCC_1997 GDPADNNADGSPRVPHP--------PRDHHFADMDANDPYRTLPTGTTVG
MMAR_0482|M.marinum_M LDRQAAIRARLGQLGIPVEGEDPTHPGTAEPPFPPPTRINGLTEHGAQRV
MUL_1133|M.ulcerans_Agy99 LDRQAVIRARLGQLGIPVEGEDPTHPGTAEPPFPPPTRINGLTEHGAQRV
MAV_3143|M.avium_104 -----VVNPNVFKDLISHSRPEHQPDGTLRYDVLINRVHCASGPLGIASC
TH_3926|M.thermoresistible__bu ---------------------GAIGAARGALMGILGGPIGVFGGGVLGFV
Mvan_5711|M.vanbaalenii_PYR-1 ---------------------GALGALRGAVLGVLGGPLGMLGGSVAGFV
Mb2102c|M.bovis_AF2122/97 ----------------PPDDPIAVEARRLAFQALHRPCNSAEWTAAVAGF
Rv2077c|M.tuberculosis_H37Rv ----------------PPDDPIAVEARRLAFQALHRPCNSAEWTAAVAGF
Mflv_1972|M.gilvum_PYR-GCK RVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDVAHDIDVFRN
MSMEG_5600|M.smegmatis_MC2_155 ----------AEIATFPPGTRADALAERMTGLHLNQADAARATDIAAARI
MAB_0016|M.abscessus_ATCC_1997 PNGERIALVSRPPDDPAWAENQTKNGKSVYVTQTEAYDVTRQPPQSLGKL
MMAR_0482|M.marinum_M EGRDGHGVN--------------DNAMQDAVAHPIEPPQFMPDQYGGTWR
MUL_1133|M.ulcerans_Agy99 EGRDGHGVN--------------DNAMQDAVAHPIEPPQFMPDQYGGTWR
MAV_3143|M.avium_104 QDT-GESLT--------------MRIVVDPRVGRADVPGGEQKGVITMFP
TH_3926|M.thermoresistible__bu GGAAG-------------------GALISGPARTAVTSAWDCL-------
Mvan_5711|M.vanbaalenii_PYR-1 GGAAG-------------------GAMISGPARTAVTSAWDCL-------
Mb2102c|M.bovis_AF2122/97 AGSSAG----------------VVGTALAIPAGPADWALLGAALLG--VG
Rv2077c|M.tuberculosis_H37Rv AGSSAG----------------VVGTALAIPAGPADWALLGAALLG--VG
Mflv_1972|M.gilvum_PYR-GCK WSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEHAVDAVNAGRHVDDAL
MSMEG_5600|M.smegmatis_MC2_155 WGETG------------GTSKMPDGSIIVLPANIRQTDVMKVFPDGSVTV
MAB_0016|M.abscessus_ATCC_1997 QGVDGSKVYQGSIVYDKASGRMYVVGNHGDGSGDTARGMWRSDPVDPNHP
. .
MMAR_0482|M.marinum_M YIGKDATVSLNENGQVTTAWANSRNGWRNP--------------------
MUL_1133|M.ulcerans_Agy99 YIGKDATVSLNENGQVTTAWANSRNGWRNP--------------------
MAV_3143|M.avium_104 LEGGSGVIQLGPKWTWTPPWVNN-NVPIN---------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 GSGAAVVNCATK--------------------------------------
Rv2077c|M.tuberculosis_H37Rv GSGAAVVNCATK--------------------------------------
Mflv_1972|M.gilvum_PYR-GCK DAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGNFGFEDANAL
MSMEG_5600|M.smegmatis_MC2_155 LRGVDVTQYLPR--------------------------------------
MAB_0016|M.abscessus_ATCC_1997 NDWVKTLRYQGDVPSLPGSRESSLVALPHGGVALFG-----------ADD
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAV_3143|M.avium_104 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK LQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATADEAASAVST
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 YAPAEGRNMAVGAISAATPEGLLQARPVTDLLPAGKTPWPGGAPYAALPT
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAV_3143|M.avium_104 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK ALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAVTGSTVRVVL
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 GVHWDPALRADVVDTRVSIWRDVPGVRGAYPPVTYQTSVPIFQPNS----
MMAR_0482|M.marinum_M -----------------
MUL_1133|M.ulcerans_Agy99 -----------------
MAV_3143|M.avium_104 -----------------
TH_3926|M.thermoresistible__bu -----------------
Mvan_5711|M.vanbaalenii_PYR-1 -----------------
Mb2102c|M.bovis_AF2122/97 -----------------
Rv2077c|M.tuberculosis_H37Rv -----------------
Mflv_1972|M.gilvum_PYR-GCK KGDGNGGWYVLTGFPKP
MSMEG_5600|M.smegmatis_MC2_155 -----------------
MAB_0016|M.abscessus_ATCC_1997 -----------------