For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
LRQASGLAREGAGTIGAAQRRVIYAVQDAHNAGFNVEEDLSVTDTRTSRTFAEQAARQAQAQALAGDIRQ RATQLIGVEHEVAAKIATATAPLNTVGFHEPPIAPSLPTPVPHNEKPQIHAVDRSWKQDPPSPMPGDPKD MTAVQARAAWDAVNADIARYNARCGRTFVLPNEQAAYDACIADKGSLLERQAAIRARLGELGVPVEGEPP PAPDPAGPQPNEGLPPPGVSPPAESNLTVGPPSRPIQQARGGESLWDENGGEWRYFPGDNYRYPHWDYNP HDSPTARWQNIPIGDLPTHK
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1984c | - | - | 100% (300) | hypothetical protein Mb1984c |
M. bovis AF2122 / 97 | Mb2102c | - | 2e-29 | 53.33% (135) | transmembrane protein |
M. bovis AF2122 / 97 | Mb0631 | - | 1e-12 | 39.44% (142) | hypothetical protein Mb0631 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_1972 | - | 7e-07 | 34.02% (97) | hypothetical protein Mflv_1972 |
M. tuberculosis H37Rv | Rv1949c | - | 1e-180 | 99.67% (300) | hypothetical protein Rv1949c |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0016 | - | 3e-07 | 28.71% (101) | hypothetical protein MAB_0016 |
M. marinum M | MMAR_0482 | - | 1e-65 | 47.88% (307) | hypothetical protein MMAR_0482 |
M. avium 104 | MAV_3647 | - | 7e-30 | 67.01% (97) | hypothetical protein MAV_3647 |
M. smegmatis MC2 155 | MSMEG_5600 | - | 3e-21 | 29.67% (273) | hypothetical protein MSMEG_5600 |
M. thermoresistible (build 8) | TH_3926 | - | 1e-09 | 31.43% (105) | PUTATIVE putative hypothetical protein Mvan_5711 |
M. ulcerans Agy99 | MUL_1133 | - | 1e-64 | 47.23% (307) | hypothetical protein MUL_1133 |
M. vanbaalenii PYR-1 | Mvan_5711 | - | 2e-06 | 29.13% (103) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment Mb1984c|M.bovis_AF2122/97 -------------------------------------------------- Rv1949c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0482|M.marinum_M -------MAASGIPDLSALLAWPTDHLTEAAAHWDNVGEHTYAVAHQLWR MUL_1133|M.ulcerans_Agy99 -------------------------------------------------- MAV_3647|M.avium_104 -----------MPVTLSQVRAWTTEHLVNAASYWSKTADQWEDVFLQMRN Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD MAB_0016|M.abscessus_ATCC_1997 ------------MPTKSEILNWRTDHLGAAAKTWGDQATQLDTAVNGAQG Mb1984c|M.bovis_AF2122/97 -----------------------------------MRQASGLAREGAGTI Rv1949c|M.tuberculosis_H37Rv ----------------WLRQRTGADLQIVSGIAEHLRQASGLAREGAGTI MMAR_0482|M.marinum_M DATS---IDWSGHAAGALRAATHADLQTTSAAVDQLQEAARVARNGASDL MUL_1133|M.ulcerans_Agy99 -----------------MRAATHADLQTTSAAVDQLQEAARVARNGASDL MAV_3647|M.avium_104 QSYS---ITWKGAGGDGLRQRTGADLSVVSGKADQLRKAAGIARNGASDI Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDI MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSADI TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAAMV Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGSAI MAB_0016|M.abscessus_ATCC_1997 ---LLDGLRGSGQFVEAFRTRLKSYIDKTRPKVDKLKSAKQVAESSEQQL . * . : Mb1984c|M.bovis_AF2122/97 GAAQRRVIYAVQDAHNAGFNVEEDLSVTDTRTSRTFAEQAARQAQAQALA Rv1949c|M.tuberculosis_H37Rv GAAQRRVIYAVQDAHNAGFNVEEDLSVTDTRTSRTFAEQAARQAQAQALA MMAR_0482|M.marinum_M YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA MUL_1133|M.ulcerans_Agy99 YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA MAV_3647|M.avium_104 GAAQRRVLYAVEDAQNAGFTVGEDLSVTDTRSSTTPADHAARQARAEAFA Mflv_1972|M.gilvum_PYR-GCK QGARSRVLEAIAEAEQDDFTVGEDLSVTDNR-AYDLETAAARMTAATEHA MSMEG_5600|M.smegmatis_MC2_155 SAAKRDALQSISDAEADGFEVNEDLSVRDTS-RVDVSTMAARYTAAREHA TH_3926|M.thermoresistible__bu DQAKEEALLVVRVAGALAFDVREDLSLVDRLATGSPAATAVRLQQSNVLA Mvan_5711|M.vanbaalenii_PYR-1 EAAKHEALTVIAATNAMGFEVADDLTVWNRMG------AALRRNDAELLG MAB_0016|M.abscessus_ATCC_1997 KGAKDKAVYAVHDPEDEDFNVNEDLSVTERR-SHSGLDRLKRAIRRRWLQ *: . : . * * :**:: : * Mb1984c|M.bovis_AF2122/97 GDIRQRATQLIGVEHEVAAKIATATAPLNTVGFHEPPIAPSLPTPVPHNE Rv1949c|M.tuberculosis_H37Rv GDIRQRATQLIGVEHEVAAKIATATAPLNTVGFHEPPIAPSLPTPVPHNE MMAR_0482|M.marinum_M GDLRQRAAQLVGLDAQVATKVTAAVAGIGSS-------FPQIPAPAAPPM MUL_1133|M.ulcerans_Agy99 GDLPQRAAQLVGLDAQVATKVTAAVAGIGSS-------FPQIPAPAAPPM MAV_3647|M.avium_104 GDIRARAEQLEGVDRKVARELTTTTADLGTVG------------TVASSG Mflv_1972|M.gilvum_PYR-GCK EFIRWRVEQLVATDALIGQQLQANAAELEGIRFEGDRDGNGTDPTIRLVD MSMEG_5600|M.smegmatis_MC2_155 ENIQWNANQLLATDTLIGRRLTAKAAELNGVRFDDEPEG----------- TH_3926|M.thermoresistible__bu ATVRVGAAQLVSTDHAVAQRLREATDDFDSFD------------------ Mvan_5711|M.vanbaalenii_PYR-1 ISVRTGAAQLAAVDHAVATELDSVTAGFDALN------------------ MAB_0016|M.abscessus_ATCC_1997 GILHTRAQELVATDNAIARKLHEIAQDLSNFHLEGPDGNTDFSGDPNHPK : . :* . : :. .: . : Mb1984c|M.bovis_AF2122/97 K----------------------------------PQIHAVD-RSWKQDP Rv1949c|M.tuberculosis_H37Rv K----------------------------------PQIHAVD-RSWKQDP MMAR_0482|M.marinum_M G----------------------------------NPVRAVDNRTFKQNP MUL_1133|M.ulcerans_Agy99 G----------------------------------NPVRAVDNRTFKQNP MAV_3647|M.avium_104 R----------------------------------DDVQPVD---AVAGL Mflv_1972|M.gilvum_PYR-GCK NKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAESAEGADTAES MSMEG_5600|M.smegmatis_MC2_155 ------------------------------------TIRAASFGDGFKQS TH_3926|M.thermoresistible__bu ----------------------------------------------FARN Mvan_5711|M.vanbaalenii_PYR-1 ----------------------------------------------IGEG MAB_0016|M.abscessus_ATCC_1997 IMGPAKPLG--------------------PIEQEDYDLGYTFLDENGNPL Mb1984c|M.bovis_AF2122/97 PSPMPGDPKDMTAVQARAAWDAVNADIARYNARCGRTFVL---------- Rv1949c|M.tuberculosis_H37Rv PSPMPGDPKDMTAVQARAAWDAVNADIARYNARCGRTFVL---------- MMAR_0482|M.marinum_M P-PAPVDPKDMTAEEARAAWADINSEIGKYNARCGRTFVL---------- MUL_1133|M.ulcerans_Agy99 P-PAPVDPKDMTAEEARAAWADINSEIGKYNARCGRTFVL---------- MAV_3647|M.avium_104 PPDIPDRIHVVCIEHARGMPWEFECLVAYPDGTTDIYHTD---------- Mflv_1972|M.gilvum_PYR-GCK PLEALLGEGETAEGQQRSSLDEALTEVAGKPVDAPPTALERILSQHTGTG MSMEG_5600|M.smegmatis_MC2_155 PFDDLLT-----KEQALAAWEKLQTDIASYNSRCAVNIVG---------- TH_3926|M.thermoresistible__bu PIIQPLSTDSDEHHFGTCFAESFKEDVGKNMVQG--VFVG---------- Mvan_5711|M.vanbaalenii_PYR-1 PVIAPIAAGDDGQSFGQCFADRFKDDIGENMVQG--VFVG---------- MAB_0016|M.abscessus_ATCC_1997 PMLDENGNVVIDPKTGRPVPDSVWGDPADNNADGSPRVPHP--------- * . Mb1984c|M.bovis_AF2122/97 ----------PNEQAAYDACIADKGSLLER----------------QAAI Rv1949c|M.tuberculosis_H37Rv ----------PNEQAAYDACIADKGSLFER----------------QAAI MMAR_0482|M.marinum_M ----------PTEQGAYDACIADKGPLLDR----------------QAAI MUL_1133|M.ulcerans_Agy99 ----------PTEQGAYDACIADKGPLLDR----------------QAVI MAV_3647|M.avium_104 ----------EDESGIFP-------------------------------- Mflv_1972|M.gilvum_PYR-GCK RGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESAQGALDDALA MSMEG_5600|M.smegmatis_MC2_155 ----------PLPPPQYAACQQELAFLQG----------------QEAAL TH_3926|M.thermoresistible__bu --------------GAIGAARG---------------------------- Mvan_5711|M.vanbaalenii_PYR-1 --------------GALGALRG---------------------------- MAB_0016|M.abscessus_ATCC_1997 --------PRDHHFADMDANDPYRTLPTG---------------TTVGPN Mb1984c|M.bovis_AF2122/97 RARLGELGVPVE---------------GEPPPAP---DPAGPQPN--EG- Rv1949c|M.tuberculosis_H37Rv RARLGELGVPVE---------------GEPPPAP---DPAGPQPN--EG- MMAR_0482|M.marinum_M RARLGQLGIPVE---------------GEDPTHPGTAEPPFPPPTRING- MUL_1133|M.ulcerans_Agy99 RARLGQLGIPVE---------------GEDPTHPGTAEPPFPPPTRING- MAV_3647|M.avium_104 -------------------------------------------------- Mflv_1972|M.gilvum_PYR-GCK QSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLNAAADEVGQG MSMEG_5600|M.smegmatis_MC2_155 RARLADFGIHPG----------------EAPSSTSSGGDLTATATQIG-- TH_3926|M.thermoresistible__bu -ALMGILGGPIG-------------------------------------- Mvan_5711|M.vanbaalenii_PYR-1 -AVLGVLGGPLG-------------------------------------- MAB_0016|M.abscessus_ATCC_1997 GERIALVSRPPD-------------DPAWAENQTKNGKSVYVTQTEAYD- Mb1984c|M.bovis_AF2122/97 --------------LPPPGVSPPAESNLTVGPPSRPIQQARGG-----ES Rv1949c|M.tuberculosis_H37Rv --------------LPPPGVSPPAESNLTVGPPSRPIQQARGG-----ES MMAR_0482|M.marinum_M --------------LTEHGAQR-VEGRDGHGVNDNAMQDAVAHPIEPPQF MUL_1133|M.ulcerans_Agy99 --------------LTEHGAQR-VEGRDGHGVNDNAMQDAVAHPIEPPQF MAV_3647|M.avium_104 -------------------------------------------------- Mflv_1972|M.gilvum_PYR-GCK RVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDVAHDIDVFRN MSMEG_5600|M.smegmatis_MC2_155 ----------AEIATFPPGTRADALAERMTGLHLNQADAARATDIAAARI TH_3926|M.thermoresistible__bu --------------VFGGGVLGFVGGAAGGALISGPARTAVTSAWDCL-- Mvan_5711|M.vanbaalenii_PYR-1 --------------MLGGSVAGFVGGAAGGAMISGPARTAVTSAWDCL-- MAB_0016|M.abscessus_ATCC_1997 ------------VTRQPPQSLGKLQGVDGSKVYQGSIVYDKASGRMYVVG Mb1984c|M.bovis_AF2122/97 LWDENG------------------GEWRYFPGDNYRYPHWDYNPHDSPTA Rv1949c|M.tuberculosis_H37Rv LWDENG------------------GEWRYFPGDNYRYPHWDYNPHDSPTA MMAR_0482|M.marinum_M MPDQYG------------------GTWRYIGKD----ATVSLNENGQVTT MUL_1133|M.ulcerans_Agy99 MPDQYG------------------GTWRYIGKD----ATVSLNENGQVTT MAV_3647|M.avium_104 -------------------------------------------------- Mflv_1972|M.gilvum_PYR-GCK WSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEHAVDAVNAGRHVDDAL MSMEG_5600|M.smegmatis_MC2_155 WGETG------------GTSKMPDGSIIVLPANIRQTDVMKVFPDGSVTV TH_3926|M.thermoresistible__bu -------------------------------------------------- Mvan_5711|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0016|M.abscessus_ATCC_1997 NHGDGSGDTARGMWRSDPVDPNHPNDWVKTLRYQGDVPSLPGSRESSLVA Mb1984c|M.bovis_AF2122/97 RWQNIPIGDLPTHK------------------------------------ Rv1949c|M.tuberculosis_H37Rv RWQNIPIGDLPTHK------------------------------------ MMAR_0482|M.marinum_M AWANSRNGWRNP-------------------------------------- MUL_1133|M.ulcerans_Agy99 AWANSRNGWRNP-------------------------------------- MAV_3647|M.avium_104 -------------------------------------------------- Mflv_1972|M.gilvum_PYR-GCK DAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGNFGFEDANAL MSMEG_5600|M.smegmatis_MC2_155 LRGVDVTQYLPR-------------------------------------- TH_3926|M.thermoresistible__bu -------------------------------------------------- Mvan_5711|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0016|M.abscessus_ATCC_1997 LPHGGVALFGADDYAPAEGRNMAVG------AISAATPEGLLQARPVTDL Mb1984c|M.bovis_AF2122/97 -------------------------------------------------- Rv1949c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0482|M.marinum_M -------------------------------------------------- MUL_1133|M.ulcerans_Agy99 -------------------------------------------------- MAV_3647|M.avium_104 -------------------------------------------------- Mflv_1972|M.gilvum_PYR-GCK LQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATADEAASAVST MSMEG_5600|M.smegmatis_MC2_155 -------------------------------------------------- TH_3926|M.thermoresistible__bu -------------------------------------------------- Mvan_5711|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0016|M.abscessus_ATCC_1997 LPAGKTPWPGGAPYAALPTGVHWDPALRADVVDTRVSIWRDVPGVRGAYP Mb1984c|M.bovis_AF2122/97 -------------------------------------------------- Rv1949c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0482|M.marinum_M -------------------------------------------------- MUL_1133|M.ulcerans_Agy99 -------------------------------------------------- MAV_3647|M.avium_104 -------------------------------------------------- Mflv_1972|M.gilvum_PYR-GCK ALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAVTGSTVRVVL MSMEG_5600|M.smegmatis_MC2_155 -------------------------------------------------- TH_3926|M.thermoresistible__bu -------------------------------------------------- Mvan_5711|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_0016|M.abscessus_ATCC_1997 PVTYQTSVPIFQPNS----------------------------------- Mb1984c|M.bovis_AF2122/97 ----------------- Rv1949c|M.tuberculosis_H37Rv ----------------- MMAR_0482|M.marinum_M ----------------- MUL_1133|M.ulcerans_Agy99 ----------------- MAV_3647|M.avium_104 ----------------- Mflv_1972|M.gilvum_PYR-GCK KGDGNGGWYVLTGFPKP MSMEG_5600|M.smegmatis_MC2_155 ----------------- TH_3926|M.thermoresistible__bu ----------------- Mvan_5711|M.vanbaalenii_PYR-1 ----------------- MAB_0016|M.abscessus_ATCC_1997 -----------------