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MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQHVLAPGGTEWEGDAKDAALE RATQNLNTVRAAGDIARSAADLAENSSADISAAKRDALQSISDAEADGFEVNEDLSVRDTSRVDVSTMAA RYTAAREHAENIQWNANQLLATDTLIGRRLTAKAAELNGVRFDDEPEGTIRAASFGDGFKQSPFDDLLTK EQALAAWEKLQTDIASYNSRCAVNIVGPLPPPQYAACQQELAFLQGQEAALRARLADFGIHPGEAPSSTS SGGDLTATATQIGAEIATFPPGTRADALAERMTGLHLNQADAARATDIAAARIWGETGGTSKMPDGSIIV LPANIRQTDVMKVFPDGSVTVLRGVDVTQYLPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5600 | - | - | 100% (383) | hypothetical protein MSMEG_5600 |
| M. smegmatis MC2 155 | MSMEG_5460 | - | 4e-48 | 51.65% (182) | hypothetical protein MSMEG_5460 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2102c | - | 4e-22 | 33.87% (186) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1972 | - | 3e-49 | 54.02% (174) | hypothetical protein Mflv_1972 |
| M. tuberculosis H37Rv | Rv2077c | - | 4e-22 | 33.87% (186) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0016 | - | 3e-11 | 28.16% (174) | hypothetical protein MAB_0016 |
| M. marinum M | MMAR_0482 | - | 1e-27 | 31.27% (307) | hypothetical protein MMAR_0482 |
| M. avium 104 | MAV_2254 | - | 3e-24 | 39.16% (166) | hypothetical protein MAV_2254 |
| M. thermoresistible (build 8) | TH_3926 | - | 7e-18 | 31.15% (183) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. ulcerans Agy99 | MUL_1133 | - | 2e-22 | 32.53% (249) | hypothetical protein MUL_1133 |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | 6e-20 | 34.95% (186) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2102c|M.bovis_AF2122/97 -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
Rv2077c|M.tuberculosis_H37Rv -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
MAV_2254|M.avium_104 -----------MPATLSQIEAWSTEHLIDAAAYWTQTADRWEDAFLTMRN
MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ
Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ
TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA
Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD
MMAR_0482|M.marinum_M -------MAASGIPDLSALLAWPTDHLTEAAAHWDNVGEHTYAVAHQLWR
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 ------------MPTKSEILNWRTDHLGAAAKTWGDQATQLDTAVNGAQG
Mb2102c|M.bovis_AF2122/97 ---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
Rv2077c|M.tuberculosis_H37Rv ---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
MAV_2254|M.avium_104 ---QAQSITWHGAGGDALRQRTGADLSVVSGKADLLRQAAGIARNGASDI
MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSADI
Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDI
TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAAMV
Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGSAI
MMAR_0482|M.marinum_M ---DATSIDWSGHAAGALRAATHADLQTTSAAVDQLQEAARVARNGASDL
MUL_1133|M.ulcerans_Agy99 -----------------MRAATHADLQTTSAAVDQLQEAARVARNGASDL
MAB_0016|M.abscessus_ATCC_1997 ---LLDGLRGSGQFVEAFRTRLKSYIDKTRPKVDKLKSAKQVAESSEQQL
. : . * . :
Mb2102c|M.bovis_AF2122/97 DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
Rv2077c|M.tuberculosis_H37Rv DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
MAV_2254|M.avium_104 SAAQRRVLYGVEDALNAGFTVGEDLSVTDTRSTSP-AERAARQAQAEAFA
MSMEG_5600|M.smegmatis_MC2_155 SAAKRDALQSISDAEADGFEVNEDLSVRDTSRVDVST-MAARYTAAREHA
Mflv_1972|M.gilvum_PYR-GCK QGARSRVLEAIAEAEQDDFTVGEDLSVTDNRAYDLET-AAARMTAATEHA
TH_3926|M.thermoresistible__bu DQAKEEALLVVRVAGALAFDVREDLSLVDRLATGSPAATAVRLQQSNVLA
Mvan_5711|M.vanbaalenii_PYR-1 EAAKHEALTVIAATNAMGFEVADDLTVWNRMG------AALRRNDAELLG
MMAR_0482|M.marinum_M YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA
MUL_1133|M.ulcerans_Agy99 YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA
MAB_0016|M.abscessus_ATCC_1997 KGAKDKAVYAVHDPEDEDFNVNEDLSVTERRSHSG-LDRLKRAIRRRWLQ
*: . : . * * :**:: : *
Mb2102c|M.bovis_AF2122/97 GDIRLRVGQLVAAENEVSGQLAATTGDVGNVRFAG---------------
Rv2077c|M.tuberculosis_H37Rv GDIRLRVGQLVAAENEVSGQLAATTGDVGNVRFAG---------------
MAV_2254|M.avium_104 ADIRLRAEQLDGADTKVSGQLTAATAGLSGGGFAQNSTSN----------
MSMEG_5600|M.smegmatis_MC2_155 ENIQWNANQLLATDTLIGRRLTAKAAELNGVRFDDEPEG-----------
Mflv_1972|M.gilvum_PYR-GCK EFIRWRVEQLVATDALIGQQLQANAAELEGIRFEGDRDGNGTDPTIRLVD
TH_3926|M.thermoresistible__bu ATVRVGAAQLVSTDHAVAQRLREATDDFDSFDFAR---------------
Mvan_5711|M.vanbaalenii_PYR-1 ISVRTGAAQLAAVDHAVATELDSVTAGFDALNIGE---------------
MMAR_0482|M.marinum_M GDLRQRAAQLVGLDAQVATKVTAAVAGIGS-SFPQIPAPAAPPMG-----
MUL_1133|M.ulcerans_Agy99 GDLPQRAAQLVGLDAQVATKVTAAVAGIGS-SFPQIPAPAAPPMG-----
MAB_0016|M.abscessus_ATCC_1997 GILHTRAQELVATDNAIARKLHEIAQDLSNFHLEGPDGNTDFSGD-----
: . :* . : :. .: . . :
Mb2102c|M.bovis_AF2122/97 ----------------------------------------APVVAHSAVQ
Rv2077c|M.tuberculosis_H37Rv ----------------------------------------APVVAHSAVQ
MAV_2254|M.avium_104 ---------------RGGRAQNSSGNGGQPQPGHNAGQPQPATTNHNGVR
MSMEG_5600|M.smegmatis_MC2_155 ------------------------------------TIRAASFGDGFKQS
Mflv_1972|M.gilvum_PYR-GCK NKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAESAEGADTAES
TH_3926|M.thermoresistible__bu ------------------------------------NPIIQPLSTDSDEH
Mvan_5711|M.vanbaalenii_PYR-1 ------------------------------------GPVIAPIAAGDDGQ
MMAR_0482|M.marinum_M ------------------------------------NPVRAVDNRTFKQN
MUL_1133|M.ulcerans_Agy99 ------------------------------------NPVRAVDNRTFKQN
MAB_0016|M.abscessus_ATCC_1997 -----------------------------PNHPKIMGPAKPLGPIEQEDY
Mb2102c|M.bovis_AF2122/97 LVDFFKQDGPTP-PPPGAPHPSGGADGPYSDPITSMMLPP----------
Rv2077c|M.tuberculosis_H37Rv LVDFFKQDGPTP-PPPGAPHPSGGADGPYSDPITSMMLPP----------
MAV_2254|M.avium_104 LVDFTQDNASGPNPPPFAPWDNPDGAPPAPAPVQPGVIPQ----------
MSMEG_5600|M.smegmatis_MC2_155 PFDDLLT-----KEQALAAWEKLQTDIASYNSRCAVNIVG----------
Mflv_1972|M.gilvum_PYR-GCK PLEALLGEGETAEGQQRSSLDEALTEVAGKPVDAPPTALERILSQHTGTG
TH_3926|M.thermoresistible__bu HFG--------------TCFAESFKEDVGKNMVQGVFVGG----------
Mvan_5711|M.vanbaalenii_PYR-1 SFG--------------QCFADRFKDDIGENMVQGVFVGG----------
MMAR_0482|M.marinum_M PPPAPVDPKDMTAEEARAAWADINSEIGKYNARCGRTFVLP---------
MUL_1133|M.ulcerans_Agy99 PPPAPVDPKDMTAEEARAAWADINSEIGKYNARCGRTFVLP---------
MAB_0016|M.abscessus_ATCC_1997 DLGYTFLDENGNPLPMLDENGNVVIDPKTGRPVPDSVWGDP---------
.
Mb2102c|M.bovis_AF2122/97 ------------------------------------------------AG
Rv2077c|M.tuberculosis_H37Rv ------------------------------------------------AG
MAV_2254|M.avium_104 ------------------------------------------------LE
MSMEG_5600|M.smegmatis_MC2_155 ----------PLPPPQYAACQQELAFLQG----------------QEAAL
Mflv_1972|M.gilvum_PYR-GCK RGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESAQGALDDALA
TH_3926|M.thermoresistible__bu -----------------------------------------------AIG
Mvan_5711|M.vanbaalenii_PYR-1 -----------------------------------------------ALG
MMAR_0482|M.marinum_M --------------------------------------------TEQGAY
MUL_1133|M.ulcerans_Agy99 --------------------------------------------TEQGAY
MAB_0016|M.abscessus_ATCC_1997 -----------------------------------------------ADN
Mb2102c|M.bovis_AF2122/97 TEAPVSDATKR---------------------------------------
Rv2077c|M.tuberculosis_H37Rv TEAPVSDATKR---------------------------------------
MAV_2254|M.avium_104 QSMTAPPAPKPG--------------------------------------
MSMEG_5600|M.smegmatis_MC2_155 RARLADFGIHPG----------------EAPSSTSSGGDLTATATQIG--
Mflv_1972|M.gilvum_PYR-GCK QSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLNAAADEVGQG
TH_3926|M.thermoresistible__bu AARGALMGILGG--------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 ALRGAVLGVLGG--------------------------------------
MMAR_0482|M.marinum_M DACIADKGPLLDR-------------------------------------
MUL_1133|M.ulcerans_Agy99 DACIADKGPLLDR-------------------------------------
MAB_0016|M.abscessus_ATCC_1997 NADGSPRVPHPPRD------------------------------------
Mb2102c|M.bovis_AF2122/97 -------WVDNMVNELAARPPDDPIAVEARRLAFQALHRPCNSAEWTAAV
Rv2077c|M.tuberculosis_H37Rv -------WVDNMVNELAARPPDDPIAVEARRLAFQALHRPCNSAEWTAAV
MAV_2254|M.avium_104 -------PPASPLPSPSVTPLPNPAAVGP--AAAAPAKPPCSPYDATKAI
MSMEG_5600|M.smegmatis_MC2_155 ----------AEIATFPPGTRADALAERMTGLHLNQADAARATDIAAARI
Mflv_1972|M.gilvum_PYR-GCK RVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDVAHDIDVFRN
TH_3926|M.thermoresistible__bu -----------PIGVFGGGVLGFVGGAAGGALISGPARTAVTSAWDCL--
Mvan_5711|M.vanbaalenii_PYR-1 -----------PLGMLGGSVAGFVGGAAGGAMISGPARTAVTSAWDCL--
MMAR_0482|M.marinum_M -----QAAIRARLGQLGIPVEGEDPTHPGTAEPPFPPPTRINGLTEHGAQ
MUL_1133|M.ulcerans_Agy99 -----QAVIRARLGQLGIPVEGEDPTHPGTAEPPFPPPTRINGLTEHGAQ
MAB_0016|M.abscessus_ATCC_1997 -HHFADMDANDPYRTLPTGTTVGPNGERIALVSRPPDDPAWAENQTKNGK
Mb2102c|M.bovis_AF2122/97 AGFAG------------SSAGVVG---TALAIPAGPADWALLGAALLGVG
Rv2077c|M.tuberculosis_H37Rv AGFAG------------SSAGVVG---TALAIPAGPADWALLGAALLGVG
MAV_2254|M.avium_104 LEPPI------------GMVGILTAVPESLTIAGIPAALTQIGVGTVAVA
MSMEG_5600|M.smegmatis_MC2_155 WGETG------------GTSKMPDGSIIVLPANIRQTDVMKVFPDGSVTV
Mflv_1972|M.gilvum_PYR-GCK WSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEHAVDAVNAGRHVDDAL
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0482|M.marinum_M RVEGRDGHGVNDNAMQDAVAHPIEPPQFMPDQYGGTWRYIGKDATVSLNE
MUL_1133|M.ulcerans_Agy99 RVEGRDGHGVNDNAMQDAVAHPIEPPQFMPDQYGGTWRYIGKDATVSLNE
MAB_0016|M.abscessus_ATCC_1997 SVYVTQTEAYDVTRQPPQSLGKLQGVDGSKVYQGSIVYDKASGRMYVVGN
Mb2102c|M.bovis_AF2122/97 GSGAAVVNCATK--------------------------------------
Rv2077c|M.tuberculosis_H37Rv GSGAAVVNCATK--------------------------------------
MAV_2254|M.avium_104 DGLDAADKCLP---------------------------------------
MSMEG_5600|M.smegmatis_MC2_155 LRGVDVTQYLPR--------------------------------------
Mflv_1972|M.gilvum_PYR-GCK DAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGNFGFEDANAL
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0482|M.marinum_M NGQVTTAWANSRNGWRNP--------------------------------
MUL_1133|M.ulcerans_Agy99 NGQVTTAWANSRNGWRNP--------------------------------
MAB_0016|M.abscessus_ATCC_1997 HGDGSGDTARGMWRSDPVDPNHPNDWVKTLRYQG-----------DVPSL
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2254|M.avium_104 --------------------------------------------------
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK LQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATADEAASAVST
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 PGSRESSLVALPHGGVALFGADDYAPAEGRNMAVGAISAATPEGLLQARP
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2254|M.avium_104 --------------------------------------------------
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK ALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAVTGSTVRVVL
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 VTDLLPAGKTPWPGGAPYAALPTGVHWDPALRADVVDTRVSIWRDVPGVR
Mb2102c|M.bovis_AF2122/97 -------------------
Rv2077c|M.tuberculosis_H37Rv -------------------
MAV_2254|M.avium_104 -------------------
MSMEG_5600|M.smegmatis_MC2_155 -------------------
Mflv_1972|M.gilvum_PYR-GCK KGDGNGGWYVLTGFPKP--
TH_3926|M.thermoresistible__bu -------------------
Mvan_5711|M.vanbaalenii_PYR-1 -------------------
MMAR_0482|M.marinum_M -------------------
MUL_1133|M.ulcerans_Agy99 -------------------
MAB_0016|M.abscessus_ATCC_1997 GAYPPVTYQTSVPIFQPNS