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RAATHADLQTTSAAVDQLQEAARVARNGASDLYAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQ RAARQAQAQAFAGDLPQRAAQLVGLDAQVATKVTAAVAGIGSSFPQIPAPAAPPMGNPVRAVDNRTFKQN PPPAPVDPKDMTAEEARAAWADINSEIGKYNARCGRTFVLPTEQGAYDACIADKGPLLDRQAVIRARLGQ LGIPVEGEDPTHPGTAEPPFPPPTRINGLTEHGAQRVEGRDGHGVNDNAMQDAVAHPIEPPQFMPDQYGG TWRYIGKDATVSLNENGQVTTAWANSRNGWRNP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1133 | - | - | 100% (314) | hypothetical protein MUL_1133 |
| M. ulcerans Agy99 | MUL_1136 | - | 1e-17 | 39.87% (153) | hypothetical protein MUL_1136 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1984c | - | 1e-64 | 47.23% (307) | hypothetical protein Mb1984c |
| M. gilvum PYR-GCK | Mflv_1972 | - | 1e-08 | 25.00% (308) | hypothetical protein Mflv_1972 |
| M. tuberculosis H37Rv | Rv1949c | - | 6e-68 | 46.77% (325) | hypothetical protein Rv1949c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0016 | - | 2e-08 | 35.42% (96) | hypothetical protein MAB_0016 |
| M. marinum M | MMAR_0482 | - | 0.0 | 99.36% (314) | hypothetical protein MMAR_0482 |
| M. avium 104 | MAV_1108 | - | 8e-48 | 58.72% (172) | hypothetical protein MAV_1108 |
| M. smegmatis MC2 155 | MSMEG_5600 | - | 2e-22 | 32.53% (249) | hypothetical protein MSMEG_5600 |
| M. thermoresistible (build 8) | TH_3926 | - | 9e-10 | 34.91% (106) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | 4e-08 | 32.11% (109) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA
Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD
Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ
MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0482|M.marinum_M -------MAASGIPDLSALLAWPTDHLTEAAAHWDNVGEHTYAVAHQLWR
Mb1984c|M.bovis_AF2122/97 --------------------------------------------------
Rv1949c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1108|M.avium_104 -------------------MAWPTDHLTEAADYWETVSERTFGIAHQVWR
MAB_0016|M.abscessus_ATCC_1997 ------------MPTKSEILNWRTDHLGAAAKTWGDQATQLDTAVNGAQG
TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAAMV
Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGSAI
Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDI
MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSADI
MUL_1133|M.ulcerans_Agy99 -----------------MRAATHADLQTTSAAVDQLQEAARVARNGASDL
MMAR_0482|M.marinum_M DATS---IDWSGHAAGALRAATHADLQTTSAAVDQLQEAARVARNGASDL
Mb1984c|M.bovis_AF2122/97 -----------------------------------MRQASGLAREGAGTI
Rv1949c|M.tuberculosis_H37Rv ----------------WLRQRTGADLQIVSGIAEHLRQASGLAREGAGTI
MAV_1108|M.avium_104 DALS---ADWRGAAAETLRGATHADMTSTSAVADQLRAAASVARGGASDL
MAB_0016|M.abscessus_ATCC_1997 ---LLDGLRGSGQFVEAFRTRLKSYIDKTRPKVDKLKSAKQVAESSEQQL
. * . :
TH_3926|M.thermoresistible__bu DQAKEEALLVVRVAGALAFDVREDLSLVDRLATGSPAATAVRLQQSNVLA
Mvan_5711|M.vanbaalenii_PYR-1 EAAKHEALTVIAATNAMGFEVADDLTVWNRMG------AALRRNDAELLG
Mflv_1972|M.gilvum_PYR-GCK QGARSRVLEAIAEAEQDDFTVGEDLSVTDNRAYDLET-AAARMTAATEHA
MSMEG_5600|M.smegmatis_MC2_155 SAAKRDALQSISDAEADGFEVNEDLSVRDTSRVDVST-MAARYTAAREHA
MUL_1133|M.ulcerans_Agy99 YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA
MMAR_0482|M.marinum_M YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA
Mb1984c|M.bovis_AF2122/97 GAAQRRVIYAVQDAHNAGFNVEEDLSVTDTRTSRTFAEQAARQAQAQALA
Rv1949c|M.tuberculosis_H37Rv GAAQRRVIYAVQDAHNAGFNVEEDLSVTDTRTSRTFAEQAARQAQAQALA
MAV_1108|M.avium_104 SAARSRVRYAVEDAHSAGFDVGEDLSIRDRTVGGSTAQRAARQAQARALA
MAB_0016|M.abscessus_ATCC_1997 KGAKDKAVYAVHDPEDEDFNVNEDLSVTERRSHSG-LDRLKRAIRRRWLQ
*: . : . * * :**:: : *
TH_3926|M.thermoresistible__bu ATVRVGAAQLVSTDHAVAQRLREATDDFDSFD---------FAR------
Mvan_5711|M.vanbaalenii_PYR-1 ISVRTGAAQLAAVDHAVATELDSVTAGFDALN---------IGE------
Mflv_1972|M.gilvum_PYR-GCK EFIRWRVEQLVATDALIGQQLQANAAELEGIR---------FEGDRDGNG
MSMEG_5600|M.smegmatis_MC2_155 ENIQWNANQLLATDTLIGRRLTAKAAELNGVR---------FDDEPEG--
MUL_1133|M.ulcerans_Agy99 GDLPQRAAQLVGLDAQVATKVTAAVAGIGSS----------FPQIPAPAA
MMAR_0482|M.marinum_M GDLRQRAAQLVGLDAQVATKVTAAVAGIGSS----------FPQIPAPAA
Mb1984c|M.bovis_AF2122/97 GDIRQRATQLIGVEHEVAAKIATATAPLNTVGFHEP---PIAPSLPTPVP
Rv1949c|M.tuberculosis_H37Rv GDIRQRATQLIGVEHEVAAKIATATAPLNTVGFHEP---PIAPSLPTPVP
MAV_1108|M.avium_104 GDIRQRAAQLVSLDQEVAGKITAAVAGVRDT----------FPHDPTANR
MAB_0016|M.abscessus_ATCC_1997 GILHTRAQELVATDNAIARKLHEIAQDLSNFHLEGPDGNTDFSGDPNHPK
: . :* . : :. .: . .
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK TDPTIRLVDNKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAES
MSMEG_5600|M.smegmatis_MC2_155 ---------------------------------------------TIRAA
MUL_1133|M.ulcerans_Agy99 PP----------------------------------------MGNPVRAV
MMAR_0482|M.marinum_M PP----------------------------------------MGNPVRAV
Mb1984c|M.bovis_AF2122/97 HN----------------------------------------EKPQIHAV
Rv1949c|M.tuberculosis_H37Rv HN----------------------------------------EKPQIHAV
MAV_1108|M.avium_104 PS----------------------------------------TDGHVRGV
MAB_0016|M.abscessus_ATCC_1997 IMGPAKPLG-----------------------------PIEQEDYDLGYT
TH_3926|M.thermoresistible__bu --------NPIIQPLSTDSDEHHFGTCFAESFKEDVG-------------
Mvan_5711|M.vanbaalenii_PYR-1 --------GPVIAPIAAGDDGQSFGQCFADRFKDDIG-------------
Mflv_1972|M.gilvum_PYR-GCK AEGADTAESPLEALLGEGETAEGQQRSSLDEALTEVAGKPVDAPPTALER
MSMEG_5600|M.smegmatis_MC2_155 SFGDGFKQSPFDDLLT-----KEQALAAWEKLQTDIASYNSRCAVNIVG-
MUL_1133|M.ulcerans_Agy99 DNRTFKQNPP-PAPVDPKDMTAEEARAAWADINSEIGKYNARCGRTFVLP
MMAR_0482|M.marinum_M DNRTFKQNPP-PAPVDPKDMTAEEARAAWADINSEIGKYNARCGRTFVLP
Mb1984c|M.bovis_AF2122/97 D-RSWKQDPPSPMPGDPKDMTAVQARAAWDAVNADIARYNARCGRTFVLP
Rv1949c|M.tuberculosis_H37Rv D-RSWKQDPPSPMPGDPKDMTAVQARAAWDAVNADIARYNARCGRTFVLP
MAV_1108|M.avium_104 DNHTFKDAPS-------SGMSREQAKAGLKDVNKRIWEHNHIDKPVIEQL
MAB_0016|M.abscessus_ATCC_1997 FLDENGNPLPMLDENGNVVIDPKTGRPVPDSVWGDPADNNADGSPRVPHP
.
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK ILSQHTGTGRGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESA
MSMEG_5600|M.smegmatis_MC2_155 -------------------PLPPPQYAACQQELAFLQG------------
MUL_1133|M.ulcerans_Agy99 T-------------------------------------------------
MMAR_0482|M.marinum_M T-------------------------------------------------
Mb1984c|M.bovis_AF2122/97 N-------------------------------------------------
Rv1949c|M.tuberculosis_H37Rv N-------------------------------------------------
MAV_1108|M.avium_104 P-------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 PRD--------------------------------------------HHF
TH_3926|M.thermoresistible__bu -----KNMVQGVFVGGAIGAAR--------------------GALMGILG
Mvan_5711|M.vanbaalenii_PYR-1 -----ENMVQGVFVGGALGALR--------------------GAVLGVLG
Mflv_1972|M.gilvum_PYR-GCK QGALDDALAQSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLN
MSMEG_5600|M.smegmatis_MC2_155 ----QEAALRARLADFGIHPG----------------EAPSSTSSGGDLT
MUL_1133|M.ulcerans_Agy99 ----EQGAYDACIADKGPLLDRQ----------------AVIRARLGQLG
MMAR_0482|M.marinum_M ----EQGAYDACIADKGPLLDRQ----------------AAIRARLGQLG
Mb1984c|M.bovis_AF2122/97 ----EQAAYDACIADKGSLLERQ----------------AAIRARLGELG
Rv1949c|M.tuberculosis_H37Rv ----EQAAYDACIADKGSLFERQ----------------AAIRARLGELG
MAV_1108|M.avium_104 ----PNDPRRADFHVETEQLNAE----------------KQQYLDVLFHQ
MAB_0016|M.abscessus_ATCC_1997 ADMDANDPYRTLPTGTTVGPNGERIALVSRPPDDPAWAENQTKNGKSVYV
.
TH_3926|M.thermoresistible__bu GPIGVFG------------GGVLGFVGGAAG-------------GALISG
Mvan_5711|M.vanbaalenii_PYR-1 GPLGMLG------------GSVAGFVGGAAG-------------GAMISG
Mflv_1972|M.gilvum_PYR-GCK AAADEVGQGRVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDV
MSMEG_5600|M.smegmatis_MC2_155 ATATQIG------------AEIATFPPGTRADALAERMTGLHLNQADAAR
MUL_1133|M.ulcerans_Agy99 IPVEGEDPTHPGTA--EPPFPPPTRINGLTEHGAQR-VEGRDGHGVNDNA
MMAR_0482|M.marinum_M IPVEGEDPTHPGTA--EPPFPPPTRINGLTEHGAQR-VEGRDGHGVNDNA
Mb1984c|M.bovis_AF2122/97 VPVEGEPPPAP-----DPAGPQPN--EGLPPPGVSPPAESNLTVGPPSRP
Rv1949c|M.tuberculosis_H37Rv VPVEGEPPPAP-----DPAGPQPN--EGLPPPGVSPPAESNLTVGPPSRP
MAV_1108|M.avium_104 HPPESVVGPHG--------EQLPGVPSGESAIGPAESGKGWQFSLPPGHA
MAB_0016|M.abscessus_ATCC_1997 TQTEAYDVTRQPPQSLGKLQGVDGSKVYQGSIVYDKASGRMYVVGNHGDG
TH_3926|M.thermoresistible__bu PARTAVTSAWDCL-------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 PARTAVTSAWDCL-------------------------------------
Mflv_1972|M.gilvum_PYR-GCK AHDIDVFRNWSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEHAVDAVN
MSMEG_5600|M.smegmatis_MC2_155 ATDIAAARIWGETG------------GTSKMPDGSIIVLPANIRQTDVMK
MUL_1133|M.ulcerans_Agy99 MQDAVAHPIEPPQFMPD-------------QYGGTWRYIGKD----ATVS
MMAR_0482|M.marinum_M MQDAVAHPIEPPQFMPD-------------QYGGTWRYIGKD----ATVS
Mb1984c|M.bovis_AF2122/97 IQQARGG-----ESLWD-------------ENGGEWRYFPGDNYRYPHWD
Rv1949c|M.tuberculosis_H37Rv IQQARGG-----ESLWD-------------ENGGEWRYFPGDNYRYPHWD
MAV_1108|M.avium_104 GIDPRVTTIRVMEPTAQ-------------YPDGYVVYMNGMG-----QT
MAB_0016|M.abscessus_ATCC_1997 SGDTARGMWRSDPVDPNHPN----DWVKTLRYQGDVPSLPGSRE--SSLV
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK AGRHVDDALDAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGN
MSMEG_5600|M.smegmatis_MC2_155 VFPDGSVTVLRGVDVTQYLPR-----------------------------
MUL_1133|M.ulcerans_Agy99 LNENGQVTTAWANSRNGWRNP-----------------------------
MMAR_0482|M.marinum_M LNENGQVTTAWANSRNGWRNP-----------------------------
Mb1984c|M.bovis_AF2122/97 YNPHDSPTARWQNIPIGDLPTHK---------------------------
Rv1949c|M.tuberculosis_H37Rv YNPHDSPTARWQNIPIGDLPTHK---------------------------
MAV_1108|M.avium_104 VNPFTGRTIPPSDDYAHIPLPE----------------------------
MAB_0016|M.abscessus_ATCC_1997 ALPHGGVALFGADDYAPAEGRNMAVGAISAATPEGLLQARPVTDLLPAGK
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK FGFEDANALLQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATA
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0482|M.marinum_M --------------------------------------------------
Mb1984c|M.bovis_AF2122/97 --------------------------------------------------
Rv1949c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1108|M.avium_104 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 TPWPGGAPYAALPTGVHWDPALRADVVDTRVSIWRDVPGVRGAYPPVTYQ
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK DEAASAVSTALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAV
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0482|M.marinum_M --------------------------------------------------
Mb1984c|M.bovis_AF2122/97 --------------------------------------------------
Rv1949c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_1108|M.avium_104 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 TSVPIFQPNS----------------------------------------
TH_3926|M.thermoresistible__bu --------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------
Mflv_1972|M.gilvum_PYR-GCK TGSTVRVVLKGDGNGGWYVLTGFPKP
MSMEG_5600|M.smegmatis_MC2_155 --------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------
MMAR_0482|M.marinum_M --------------------------
Mb1984c|M.bovis_AF2122/97 --------------------------
Rv1949c|M.tuberculosis_H37Rv --------------------------
MAV_1108|M.avium_104 --------------------------
MAB_0016|M.abscessus_ATCC_1997 --------------------------